April 2011

Chemical composition and biological activity of the volatile oils of Hyptis spicigera against Trypanosoma brucei brucei, (Tbb) found in Northern Nigeria

The hydrodistillation of the fresh leaves of Hyptis spicigera gave a colourless volatile oil with yield of 0.65%.The volatile oil gave forty compounds on the basis of  gas chromatography-mass spectroscopy (GC-MS) with low composition of cineole(4.11%) and caryophyllene (2.61%) while α-pinene (12.16%) β-pinene(9.47%) and α-phellandrene (10.19%) were predominant compounds. The...

Author(s): Z. Ladan, J. O. Amupitan, O. A. Oyewale, E. M. Okonkwo, E. O. Ladan, B. Odjobo and N. Habila

April 2011

Synthesis, characterization and trypanocidal activity of some aromatic thiosemicarbazones and their 1,3,4-thiadiazolines derivatives

The thiosemicarbazones of six aromatic ketones were synthesized as well as their 1,3,4-thiadiazolines derivatives obtained by cyclization under acetylating condition with yields going from 40 to 90%. The products purity was confirmed by mass spectrometry coupled with high-performance liquid chromatography (LC/MS) and there were characterized using spectrometry IR, NMR 1H and 13C (nuclear magnetic...

Author(s): Houssou Raymond Fatondji, Fernand Gbaguidi, Salomé Kpoviessi, Joanne Bero, Veronique Hannaert, Joëlle Quetin-Leclercq, Jacques Poupaert, Mansourou Moudachirou and Georges Coffi Accrombessi

April 2011

Preliminary phytochemical and antimicrobial screening of the leaf extract of Cassia singueana Del

Ethanolic and aqueous extracts of Cassia singueana Del. leaves were screened for their antimicrobial activity against Staphylococcus aureus, Streptococcus pyogen,Escherichia coli, Salmonella typii and Shigella dysentery. The result indicated that the extracts inhibited the growth of one or more test pathogens. The ethanolic extract showed a broad spectrum of...

Author(s): Olusola Adeyanju, Olajide Olutayo O, Afolayan Michael and Khan IZ

April 2011

Multiple regression analyses of kinetics of aquation reactions of some chromium (III) – alkyl amine complexes in mixed solvent media- A study of solvation mechanics

Molecular dynamics of the aquation reactions of the complexes  [Cr(en)2Cl2]Cl,[Cr(tn)2Cl2]Cl,[Cr(tetren)Cl]Cl2, [Cr(pn)2Cl2]Cl, [Cr(trien)Cl2]Cl and [Cr(dien)Cl3] have been extensively studied in mixed solvent media. Kinetics and thermodynamic parameters have been evaluated and the results are interpreted carefully in the light of statistical and regression models.   Key words: Cr (III) complexes,...

Author(s): A. Rajendran and K. Anbalagan