African Journal of
Pharmacy and Pharmacology

  • Abbreviation: Afr. J. Pharm. Pharmacol.
  • Language: English
  • ISSN: 1996-0816
  • DOI: 10.5897/AJPP
  • Start Year: 2007
  • Published Articles: 2288

Full Length Research Paper

A comparative study on antioxidant activity of ten different parts of Nelumbo nucifera Gaertn.

Yan-Bin Wu 1#, Li-Jun Zheng 1#, Jun Yi 2, Jian-Guo Wu1, Chun-Jiang Tan1, Ti-Qiang Chen 3, Jin-Zhong Wu 1* and Ka-Hing Wong4*
1Academy of Integrative Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian 350108, P.R. China. 2Department of Chemistry and Life Science, Fujian institute of education, Fuzhou, Fujian 350001, China. 3Institute of Edible and Medicinal Fungi, Fujian Academy of Agricultural Sciences, Fuzhou 350013, China. 4Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hong Kong, China.
Email: [email protected], [email protected]

  •  Accepted: 08 July 2011
  •  Published: 15 December 2011

Abstract

The in vitro antioxidant activity of ten different parts of lotus (Nelumbo nucifera Gaertn.) was evaluated and compared. Among the ten lotus extracts, the receptacle did not only possessed the highest phenolic, flavonoid and proanthocyanidin contents, but its 2-picrylhydrazyl free (DPPH) and 2, 2'-Azinobis (3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) radical scavenging activities, reducing power as well as total antioxidant activity were also comparable to, if not better than those of the butylated hydroxytoluene (BHT)  control (p < 0.05). Compared with the BHT, all ten lotus extracts even exhibited significantly (p < 0.05) higher metal chelating activity. Nevertheless, the hydroxyl radical scavenging ability of all ten lotus extracts was significantly (p < 0.05) lower than that of the ascorbic acid control. In contrast to the metal chelating ability, phenolic compounds in the ten lotus extracts would likely be responsible for their DPPH and ABTS radical scavenging activities.

 

Key words: Louts (Nelumbo nucifera), total phenolic content, total flavonoid content, total proanthocyanidin content, antioxidant activity.