African Journal of
Pharmacy and Pharmacology

  • Abbreviation: Afr. J. Pharm. Pharmacol.
  • Language: English
  • ISSN: 1996-0816
  • DOI: 10.5897/AJPP
  • Start Year: 2007
  • Published Articles: 2184

Table of Content: 15 December, 2011; 5(22)

December 2011

Formulation of herbal conditioner shampoo by using extract of fenugreek seeds and evaluation of its physicochemical parameters

Nowadays, people are interested in hair preparations and conditioner materials, such asshampoos. Hair tonic and conditioner formulations containing herbal extracts, such as fenugreek, can prevent hair loss and retain hair conditioning. First of all, the proved...

Author(s): Gholamreza Dehghan Noudeh, Fariba Sharififar, Payam Khazaeli, Ehsan Mohajeriand Javad Jahanbakhsh

December 2011

Immuno-stabilizing effect of thymosin-alpha-1 on post-modified radical mastectomy (MRM) of breast cancer patients

Thymosin-alpha-1 (Tα1), a synthetic thymus hormone, can increase the production of T cells. It may counteract the suppressed immunity of chemotherapy patients, thus restoring normal immune mechanism. This study aims to investigate the effect of thymosin-alpha-1 on the post-operation conditions of patients who have received modified radical mastectomy (MRM). Thirty-six consented patients with invasive breast ductal...

Author(s): Danyang Dou, Wanjun Tao, Lingling Li, Tingjian Jia, Wings TY Loo,, Mary NB Cheung, Louis WC Chow, Yiding Dou and Ziyuan Luo

December 2011

Investigation on intera-specific biodiversity of 6 local silkworm germplasm based on aspartate amino transferase, alanin amino transferase, alkaline phosphatase, phosphorus, sodium, potassium and iron

In the present study, an attempt has been made to analyze the profiles and biochemical composition of aspartate amino transferase (AST), alanin amino transferase (ALT), alkaline phosphatase (ALP), phosphorus, sodium, potassium and iron in six local groups of silkworm,Bombyx mori L. Six local silkworm varieties were used in the present study. These varieties included: (1) Lemon Khorasan; (2) Lemon Haratee, (3) White...

Author(s): Alireza Seidavi

December 2011

Cholesterol metabolism regulation and antioxidant effect of platycodin D on hyperlipidemic emulsion-reduced rats

To study the potential mechanisms underlying cholesterol metabolism regulation and the antioxidant of platycodin D derived from Platycodon grandiflorum A.DC (PD), the male Wistar rats treated with hyperlipidemic emulsion diet for 2 weeks were fed with PD (10, 20 and 30 mg/kg body weight/d) and simvastatin (25 mg/kg body weight/d), respectively by gavage for 28 days. Different doses of PD depressed the serum...

Author(s): Jingtao Wu, #, Guiwen Yang#, Wujun Wen, Fumiao Zhang, Jinduo Yuan and Liguo An

December 2011

A comparative study on antioxidant activity of ten different parts of Nelumbo nucifera Gaertn.

The in vitro antioxidant activity of ten different parts of lotus (Nelumbo nucifera Gaertn.) was evaluated and compared. Among the ten lotus extracts, the receptacle did not only possessed the highest phenolic, flavonoid and proanthocyanidin contents, but its 2-picrylhydrazyl free (DPPH) and 2, 2'-Azinobis (3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) radical scavenging activities,...

Author(s): Yan-Bin Wu #, Li-Jun Zheng #, Jun Yi , Jian-Guo Wu, Chun-Jiang Tan, Ti-Qiang Chen , Jin-Zhong Wu  and Ka-Hing Wong

December 2011

Deer skin glue improves erectile function in rats

Deer skin glue, extracted from deer skin under high temperature and pressure, was a kind of traditional Chinese materia medica, whose tonifying function was recorded a lot. This experiment aimed to investigate its effects on sexual organ index, the level of testosterone (T), luteinizing hormone (LH), endothelial nitric oxide synthase (eNOS) and phosphodiesterase-5(PDE5) expressions in corpus cavernosum....

Author(s): Xiao-hong Tan, Han Dong, Fu-cui Ma and Dai-cheng Liu

December 2011

Efficacy and safety of parecoxib sodium after renal transplantation

Author(s):  Lei Pang, Xin Lian, Yanhui Li, Ling Nan and Haichun Ma

December 2011

The effects of hydrodistillation and solvent free microwave extraction methods on the chemical composition and toxicity of essential oils from the leaves of Mentha longifolia L. subsp. capensis.

The effects of hydrodistillation (HD) and solvent free microwave extraction (SFME) methods on the chemical composition and toxicity of Mentha longifolia subsp. capensis leaves were studied. Colourless oils of 1.52 and 1.63% (wet/dry weight) were obtained from HD and SFME methods, respectively. Analyses of the two oils revealed a total of 21 components. These accounted for about 80% of the total...

Author(s): O. O. Okoh and A. J. Afolayan

December 2011

Adoption of WHO standard operating procedures for blood screening in hospitals of Islamabad, Pakistan

The study was conducted with the objectives to investigate the adoption of WHO standard operating procedures (SOP) for blood screening in hospitals of Islamabad. For the current study, a comprehensive questionnaire was designed and the data were collected from three main hospitals of Islamabad. The study revealed that standard operating procedures were not followed in majority of the hospitals of Islamabad. The SOP was...

Author(s): Atta Ur Rehman

December 2011

Antioxidant properties and cytotoxicity evaluation of methanolic extract of dried and fresh rhizomes of Tulbaghia violacea

The rhizomes of Tulbaghia violacea Harv. used in Eastern Cape of South Africa for the treatment of heart diseases and several human ailments was investigated for antioxidant activity. The phytochemical content and toxicity of the fresh and dried rhizomes was also evaluated. Antioxidant activity was determined by spectrophotometric methods such as 2, 2-diphenyl-2-picrylhydrazyl (DPPH), hydrogen peroxide and...

Author(s): O. S. Olorunnisola, G. Bradley and A. J. Afolayan

December 2011

Effect of the plant growth regulator (4-Chlorophenoxy acetıc acıd) ınto the oxıdatıve stress parameters in rat liver

4-Chlorophenoxy acetic acid (4-CPA) is one of the plant growth regulators that are widely used in greenhouses to increase yield and the quality of products. Plant growth regulators do not produce significant effects on organisms; however, their remnants on plants due to either high dose or inappropriate use may lead to certain adverse effects on humans. High doses of 4-CPA have been reported to cause hepatocellular...

Author(s): Duygu Tozcu Altın, Çiğdem Özer , Ediz Yeşilkaya, Aydan Babül, Aysun Bideciand Peyami Cinaz

December 2011

CXC chemokine ligand 12 (CXCL12) via its cognate receptor (CXCR4) controls the chemotaxis of multiple myeloma cell line (U266) via PI3K/AKT, PLCβ3, RhoA, NFκB and ERK1/2

In multiple myeloma (MM), malignant plasma cells reside in the bone marrow, where they accumulate in close contact with stromal cells. Chemotaxis of malignant plasma cells and stromal cells in the surrounding microenvironment is an essential component of tumour dissemination during progression and metastasis. The mechanisms responsible for the chemotaxis of malignant plasma cells in the bone marrow are still...

Author(s): Gamal Badr,

December 2011

The effects of dialysers on some blood biochemical parameters in hemodialysis patients

The aim of this study is to compare some blood biochemical parameters in hemodialysis (HD) patients treated with different dialyser filters. In 70 hemodialysis patients, in six-month period, the monthly retrospective analysis of blood biochemical values has been studied. The differences in urea input/output, creatine input/output and phosphorus (P) levels were evaluated. The dialyser blood flow rate was found to be...

Author(s): Yazar Hayrullah, Balci Mehmet, Basarali Kemal Mustafa, Gocmen Ayse Yesimand Buyukbas Sadik