African Journal of
Pharmacy and Pharmacology

  • Abbreviation: Afr. J. Pharm. Pharmacol.
  • Language: English
  • ISSN: 1996-0816
  • DOI: 10.5897/AJPP
  • Start Year: 2007
  • Published Articles: 2287

Full Length Research Paper

Evaluation of the antioxidant activity, antimicrobial effect and acute toxicity from leaves of Allophylus edulis (A. St.-Hil., A. Juss. Cambess &.) Hieron. ex Niederl

Cleide Adriane Signor Tirloni
  • Cleide Adriane Signor Tirloni
  • Faculdade de Ciencias da Saude - FCS, Universidade Federal da Grande Dourados, CEP 79804-970, Dourados, Mato Grosso do Sul, Brasil.
  • Google Scholar
Luis Fernando Benites Macorini
  • Luis Fernando Benites Macorini
  • Faculdade de Ciencias da Saude - FCS, Universidade Federal da Grande Dourados, CEP 79804-970, Dourados, Mato Grosso do Sul, Brasil.
  • Google Scholar
Uilson Pereira dos Santos
  • Uilson Pereira dos Santos
  • Faculdade de Ciencias da Saude - FCS, Universidade Federal da Grande Dourados, CEP 79804-970, Dourados, Mato Grosso do Sul, Brasil.
  • Google Scholar
Paola dos Santos da Rocha
  • Paola dos Santos da Rocha
  • Faculdade de Ciencias Biologicas e Ambientais - FCBA, Universidade Federal da Grande Dourados, CEP 79804-970, Dourados, Mato Grosso do Sul, Brasil
  • Google Scholar
Salete Verônica Barros
  • Salete Verônica Barros
  • Faculdade de Ciencias Biologicas e Ambientais - FCBA, Universidade Federal da Grande Dourados, CEP 79804-970, Dourados, Mato Grosso do Sul, Brasil
  • Google Scholar
Adriana Mary Mestriner Felipe de Mello
  • Adriana Mary Mestriner Felipe de Mello
  • Faculdade de Ciencias Biologicas e da Saude, Centro Universitario da Grande Dourados, Jardim Universitario, CEP 79824-900, Dourados, Mato Grosso do Sul, Brasil.
  • Google Scholar
Maria do Carmo Vieira
  • Maria do Carmo Vieira
  • Faculdade de Agronomia - FCA, Universidade Federal da Grande Dourados, CEP 79804-970, Dourados, Mato Grosso do Sul, Brasil.
  • Google Scholar
Kely de Picoli Souza
  • Kely de Picoli Souza
  • 1. Faculdade de Ciencias da Saude - FCS, Universidade Federal da Grande Dourados, CEP 79804-970, Dourados, Mato Grosso do Sul, Brasil., 2. Faculdade de Ciencias Biologicas e Ambientais - FCBA, Universidade Federal da Grande Dourados, CEP 79804-970, Dourados, Mato Grosso do Sul, Brasil.
  • Google Scholar
Edson Lucas dos Santos*
  • Edson Lucas dos Santos*
  • 1. Faculdade de Ciencias da Saude - FCS, Universidade Federal da Grande Dourados, CEP 79804-970, Dourados, Mato Grosso do Sul, Brasil., 2. Faculdade de Ciencias Biologicas e Ambientais - FCBA, Universidade Federal da Grande Dourados, CEP 79804-970, Dourados, Mato Grosso do Sul, Brasil.
  • Google Scholar


  •  Received: 09 January 2015
  •  Accepted: 16 March 2015
  •  Published: 22 March 2015

References

Abreu DCA, Nogueira AC, Medeiros AC de S (2005). Caracterização morfológica de frutos, sementes e germinação de Allophylus edulis (St.-Hil) Radlk. (Sapindaceae). Rev. Bras. Sementes 2:59-66.
crossref
 
Alves EOM, Soares TS, Vieira M do Carmo, Silva CB (2008). Levantamento etnobotânico e caracterização de plantas medicinais em fragmentos florestais de Dourados, MS. Ciênc. Agrotec. 32: 651-658.
crossref
 
Asare GA., Addo P, Bugyei K, Gyan B, Adjei S, Otu-Nyarko LS, Wiredu EK, Nyarko A (2011). Acute toxicity studies of aqueous leaf extract of Phyllanthus niruri. Interdiscip. Toxicol. 4:206-210.
crossref
 
Bakker-Woudenberg IA, van Vianen W, van Soolingen D, Verbrugh HA, van Agtmael MA (2005). Antimycobacterial agents differ with respect to their bacteriostatic versus bactericidal activities in relation to time of exposure, mycobacterial growth phase, and their use in combination. Antimicrob. Agents Chemother. 49(6):2387-2398.
crossref
 
Bandoni ALM, Rondina RVD, Coussio JD (1972). Survey of Argentine medicinal plants. Folklore and phytomedicine screening. Lloydia 35:69-80.
Pubmed
 
Barbosa WLR, Quignard E, Tavares ICC, Pinto LN, Oliveira FQ, de Oliveira RM (2004). Manual para Análise Fitoquímica e Cromatográfica de Extratos Vegetais. Revis. Cient. UFPA 4.
 
Braun CAA (2009). Fisiopatologia: Alterações funcionais na saúde humana. Artmed 1:123-147.
 
Burda S, Oleszek W (2001). Antioxidant and antiradical activities of flavonoids. J. Agric. Food Chem. 49:2774-2779.
crossref
 
Burton GJ, Jauniaux E (2011). Oxidative stress. Best. Pract. Res. Clin. Obst. Gynaecol. 25:287-299.
crossref
 
Bussmann RW, Malca-Garcia G, Glenn A, Sharon D, Chait G, Diaz D, Pourmand K, Jonat B, Somogy S, Guardado G, Aguirre C, Chan R, Meyer K, Kuhlman A, Townesmith A, Effio-Carbajal J, Frias-Fernandez F, Benito M (2010). Minimum inhibitory concentrations of medicinal plants used in Northern Peru as antibacterial remedies. J. Ethnopharmacol. 132: 101-108.
crossref
 
Calixto JB (2005). Twenty-fiveyears of research on medicinalplants in Latin America: A personal view. J. Ethnopharmacol. 100:131-134.
crossref
 
Campos JF, dos Santos UP, Macorini LF, de Melo AM, Balestieri JB, Paredes-Gamero EJ, Cardoso CA, de Picoli Souza K, dos Santos EL (2014). Antimicrobial, antioxidant and cytotoxic activities of propolis from Melipona orbignyi (Hymenoptera, Apidae). Food Chem Toxicol. 65:374-380.
crossref
 
Casagrande JC, Macorini LF, Antunes KA, Santos UP, Campos JF, Dias-Júnior NM, Sangalli A, Lima Cardoso CA, do Carmo Vieira M, Rabelo LA, Paredes-Gamero EJ, Dos Santos EL, de Picoli Souza K (2014). Antioxidant and cytotoxic activity of hydroethanolic extract from Jacaranda decurrens leaves. PLoS One. 9(11):e112748.
crossref
 
Cowan MM (1999). Plant Products as Antimicrobial Agents. Clin. Microbiol. Rev. 12:564-582.
Pubmed
 
Cushnie TP, Lamb AJ (2005). Antimicrobial activity of flavonoids. Int. J. Antimicrob. Agents 26:343-356.
crossref
 
Diaz M, Gonzalez A, Castro-Gamboa I, Gonzalez D, Rossini C (2008). First record of L-quebrachitol in Allophylus edulis (Sapindaceae). Carbohydr. Res. 343:2699-2700.
crossref
 
Díaz M, Castillo L, Díaz CE, Álvarez RG, González-Coloma A, Rossini C (2014). Differential deterrent activity of natural products isolated from Allophylus edulis (Sapindaceae). Advances in Biological Chemistry 4:168-179.
crossref
 
Dryden GW, Song M, McClain C (2006). Polyphenols and gastrointestinal diseases. Curr. Opin. Gastroenterol. 22:165-170.
crossref
 
Engels C, Schieber A, Ganzle MG (2011). Inhibitory spectra and modes of antimicrobial action of gallotannins from mango kernels (Mangifera indica L.). Appl. Environ. Microbiol. 77:2215-2223.
crossref
 
Farber JL (1994). Mechanisms of cell injury by activated oxygen. Environ. Health. Perspct. 102:17-24.
crossref
 
Félix-Silva J, Giordani RB, da Silva-Jr AA, Zucolotto SM, Fernandes-Pedrosa Mde F (2014). Jatropha gossypiifolia L. (Euphorbiaceae): A Review of traditional uses, phytochemistry, pharmacology, and toxicology of this medicinal plant. Evid. Based Complement. Alternat Med. 2014:369204.
crossref
 
Garg V, Dhar VJ, Sharma A, Dutt R (2012). Facts about standardization of herbal medicine: a review. Zhong Xi Yi Jie He Xue Bao 10:1077-1083.
crossref
 
Guay DR (2003). Treatment of bacterial skin and skin structure infections. Expert. Opin. Pharmacother. 4:1259-1275.
crossref
 
Gupta D, Gupta RK (2011). Bioprotective properties of Dragon's blood resin: in vitro evaluation of antioxidant activity and antimicrobial activity. BMC Complement. Altern. Med. 11:13-22.
crossref
 
Halliwell B (1992). Reactive oxygen species and the central nervous system. J. Neurochem. 59: 1609-1623.
crossref
 
Hendra R, Ahmad S, Sukari A, Shukor MY, Oskoueian E (2011). Flavonoid Analyses and Antimicrobial Activity of Various Parts of Phaleria macrocarpa (Scheff.) Boerl. Fruit. Int. J. Mol. Sci. 12:3422-3431.
crossref
 
Kamicker BJ, Sweeney MT, Kaczmarek F, Dib-Hajj F, Shang W, Crimin K, Duignan J, Gootz TD (2008). Bacterial efflux pump inhibitors. Methods. Mol. Med. 142:187-204.
crossref
 
Lee SK, Mbwambo ZH, Chung H, Luyengi L, Gamez EJ, Mehta RG, Kinghorn AD, Pezzuto, JM (1998). Evaluation of the antioxidant potential of natural products. Comb. Chem. High. Throughput. Screen 1:35-46.
crossref
 
Liberio SA, Pereira ALA, Dutra RP, Reis AS, Araújo MJAM, Mattar NS, Silva LA, Ribeiro, MN, Nascimento, FR, Guerra, RN, Monteiro-Neto V (2011). Antimicrobial activity against oral pathogens and immunomodulatory effects and toxicity of geopropolis produced by the stingless bee Melipona fasciculata Smith. BMC Complement. Altern. Med. 11:1–10.
crossref
 
McClatchey, WC, Mahady, GB, Bennett, BC, Shiels, L, Savo, V (2009). Ethnobotany as a pharmacological research tool and recent developments in CNS-active natural products from ethnobotanical sources. Pharmacol. Ther. 123:239-254.
crossref
 
Meda A, Lamien CE, Romito M, Millogo J, Nacoulma OG (2005). Determination of the total phenolic, flavonoid and proline contents in Burkina Fasan honey, as well as their radical scavenging activity. Food Chem. 91:571-577.
crossref
 
Middleton E Jr (1998). Effect of plant flavonoids on immune and inflammatory cell function. Adv. Exp. Med. Biol. 439: 175-182.
crossref
 
Mokale KAL, Ngono Ngane RA, Kuiate JR, Koanga Mogtomo ML, Tchinda Tiabou A, Mouokeu RS, Biyiti L, Amvam Zollo PH (2011). Antibacterial and Antioxidant Properties of the Methanolic Extract of the Stem Bark of Pteleopsis hylodendron (Combretaceae). Chemother Res. Pract. 2011:218750.
 
NCCLS (2005). Performance standards for antimicrobial disk susceptible test: Approved standard M2-A8, 15 ed., CLSI/NCCLS document M100-S15[ISBN 1-56238-556-9 Wayne. Organisation for Economic Co-operation and Development (OECD) (2008). Guide- line 425:Acute Oral Toxicity–Up-and-Down-Procedure, 4. Head of Publications Service, Paris, p. 27.
 
Raposo RBN, Silva FA, Polonini (2014). Antioxidant plants from Brazil. In Dubey NK. Plants as a natural Antioxidants. Chapter 4:97-109.
 
Russell AD (2002). Antibiotic and biocide resistance in bacteria: introduction. Symp. Ser. Soc. Appl. Microbiol. 31:1S-3S.
crossref
 
Silva BM, Santos RP, Mendes LS, de Pinho PG, Valentão P, Andrade PB, Pereira JA, Carvalho M (2011). Dracaena draco L. fruit: Phytochemmical and antioxidant activity assessment. Food. Res. Internat. 44:2182-2189.
crossref
 
Simões CM, Gosman G, Mello JCP, Mentz LA, Petrovick PR (2004). Farmacognosia da planta ao medicamento. Edititora URGS 5:1102. Umeo SH, Ito TM, Yokota ME, Romagnolo MB, Laverde-Junior A (2011). Avaliação das propriedades antioxidantes, anticolinesterásicas e citotóxicas dos frutos de Allophylus edulis (A.St.-Hil., Cambess. & A. Juss.) Radlk. (Sapindaceae). Arq. Cien.Saúde 15:167-171.
 
Valente MJ, Baltazar AF, Henrique R, Estevinho L, Carvalho M (2011). Biological activities of Portuguese propolis: Protection against free radical-induced erythrocyte damage and inhibition of human renal cancer cell growth in vitro. Food Chem. Toxicol. 49:86-92.
crossref
 
Yajia ME, Martí DA, Bidau AG, Amat AG, Silvestroni A (1999). Genotoxicity evaluation of Allophylus edulis (Camb.) Radlk. (Sapindaceae) aqueous extract. Acta Horticul. 501:31-35.