African Journal of
Pharmacy and Pharmacology

  • Abbreviation: Afr. J. Pharm. Pharmacol.
  • Language: English
  • ISSN: 1996-0816
  • DOI: 10.5897/AJPP
  • Start Year: 2007
  • Published Articles: 2296

Full Length Research Paper

Prevalence and the level of evidences supporting off-label prescribing of antidepressant, antipsychotic and antiepileptic drugs in Makkah Almukarramah: A case sectional study

Yosra Al-Hindi
  • Yosra Al-Hindi
  • Department of clinical pharmacy, Faculty of Pharmacy, University of Umm Al-Qura, Makkah, Saudi Arabia.
  • Google Scholar
Amal Al-sulami
  • Amal Al-sulami
  • Department of clinical pharmacy, Faculty of Pharmacy, University of Umm Al-Qura, Makkah, Saudi Arabia.
  • Google Scholar
Aseel Al-ghamdi
  • Aseel Al-ghamdi
  • Department of clinical pharmacy, Faculty of Pharmacy, University of Umm Al-Qura, Makkah, Saudi Arabia.
  • Google Scholar
Nuha Al-Harbi
  • Nuha Al-Harbi
  • Department of clinical pharmacy, Faculty of Pharmacy, University of Umm Al-Qura, Makkah, Saudi Arabia.
  • Google Scholar
Huda Hamdi
  • Huda Hamdi
  • Department of clinical pharmacy, Faculty of Pharmacy, University of Umm Al-Qura, Makkah, Saudi Arabia.
  • Google Scholar
Shooq Al-moqati
  • Shooq Al-moqati
  • Department of clinical pharmacy, Faculty of Pharmacy, University of Umm Al-Qura, Makkah, Saudi Arabia.
  • Google Scholar
Yara Abualkair
  • Yara Abualkair
  • Department of clinical pharmacy, Faculty of Pharmacy, University of Umm Al-Qura, Makkah, Saudi Arabia.
  • Google Scholar
Arwa Fairaq
  • Arwa Fairaq
  • Department of clinical pharmacy, Faculty of Pharmacy, University of Umm Al-Qura, Makkah, Saudi Arabia.
  • Google Scholar


  •  Received: 21 March 2020
  •  Accepted: 20 May 2020
  •  Published: 30 June 2020

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Eguale T, Buckeridge DL, Winslade NE, Benedetti A, Hanley JA, Tamblyn R (2012). Drug, Patient, and Physician Characteristics Associated With Off-label Prescribing in Primary Care. Archives of Internal Medicine 172(10): 
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Onyenwenyi AJ (2008). Off-label prescribing of anticonvulsant drugs. (Order No. 3381471, University of Florida). ProQuest Dissertations and Theses, p. 184.

 

Park Susie H, Pharm D, BCPP, FCSHP (2013). Off-label use of atypical antipsychotics: Lack of evidence for their use in primary insomnia. Formulary 48(11):361-362,365-368,370-376. 

 

Rahajeng B, Ikawati Z, Andayani TM, Dwiprahasto I (2018). A Retrospective Study: The Off-Label Use Of Anticonvulsants At A Private Hospital In Indonesia. International Journal of Pharmacy and Pharmaceutical Sciences 10(5):119. 
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Sartori SB, Singewald N (2019). Novel pharmacological targets in drug development for the treatment of anxiety and anxiety-related disorders. Pharmacology and Therapeutics 107402.
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Shrestha R, Prajapati S (2019). Assessment of prescription pattern and prescription error in outpatient Department at Tertiary Care District Hospital, Central Nepal. Journal of Pharmaceutical Policy and Practice 12(1):16.
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Varghese D, Carroll N (2015). Resource Utilization and costs associated with off-label use of atypical Antipsychotics in a Community-Dwelling Adult Population: Findings from the Medical Expenditure Survey. Value in Health 18(3):
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Walton SM, Schumock GT, Lee K, Alexander GC, Meltzer D, Stafford RS (2008). Prioritizing Future Research on Off-Label Prescribing: Results of a Quantitative Evaluation. Pharmacotherapy. The Journal of Human Pharmacology and Drug Therapy 28(12):1443-1452. 
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Wittich CM, Burkle CM, Lanier WL. (2012). Ten common questions (and theiranswers) about off-label drug use. Mayo Clinic Proceedings. 356:982-90.
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Wong J, Motulsky A, Abrahamowicz M, Eguale T, Buckeridge DL, Tamblyn R (2017). Off-label indications for antidepressants in primary care: Descriptive study of prescriptions from an indication based electronic prescribing system. BMJ 356, j603.
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Wong J, Motulsky A, Eguale T, Buckeridge DL, Abrahamowicz M, Tamblyn R (2016). Treatment Indications for Antidepressants Prescribed in Primary Care in Quebec, Canada, 2006-2015. Jama 315(20):2230.
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