June 2020

Phytochemical screening and toxicological effects of Amblygonocarpus andongensis aqueous stem bark extract in wistar albino rat

Amblygonocarpus andongenesis is being used as antipsychotic. Hence, it may portend high risk of toxicosis. In view of this, phytochemical screening and toxicological effects of aqueous stem bark extract of the plant was studied in wistar albino rats. Qualitative screening of the stem bark extract revealed the presence of alkaloid, hydrolysable tannin, saponin, glycoside, cardiac glycoside, saponin glycoside and...

Author(s): Abdullahi Aliyu Ebbo, Abdullahi Teleh Elsa, Emmanuel Udok Etuk, Muhammad Jengebe Ladan and Saganuwan Alhaji Saganuwan

June 2020

Nutritional characterization pulp of Chrysobalanus icaco L.

After Southeast Asia, Brazil is the second largest producer of tropical fruits having more than 500 species, and many of these have high potential regarding nutritional content that can be marketed. Among them, Chrysobalanus icaco L., which can be found in abundance in several countries of South America stands out. Among its nutritional profile, it had low value of titratable acidity (0.41 ± 0.02%) and lipid...

Author(s): Selvin Antonio Saravia Maldonado, Ismael Montero Fernández, Luis Antonio Beltrán Alemán, Ricardo Santos Alemán and Jhunior Abrahan Marcia Fuentes  

June 2020

Nutrients in Amazonian fruit pulps with functional and pharmacological interest

In this research, nine fruits cultivated in Northern Amazon were studied: Abiu, acerola, araçá, bacupari, biribá, camu-camu, fruta-do-conde, graviola and taperebá, with the objective of carrying out a proximate and nutritional study of the pulps of the Northern Amazon fruits. They were graviola (76.83 ± 0.02 Kcal 100 g-1), bacupari (53.15 ± 0.02 Kcal 100 g-1) and fruta-do-conde...

Author(s): Montero I. F., Saravia S. A. M., Santos R. A., dos Santos R. C., Marcía J. A. F. and da Costa H. N. R.  

June 2020

Prevalence and the level of evidences supporting off-label prescribing of antidepressant, antipsychotic and antiepileptic drugs in Makkah Almukarramah: A case sectional study

Off-label prescribing is very common among physicians, particularly among psychiatrists and there is limited information regarding the extent of the unapproved drug use in Makkah city. The objective of this study was to assess the prevalence of off-label indications for antidepressant, antipsychotic and antiepileptic and the strength of evidence supporting use of the prescribed drug for the respective indication. A case...

Author(s): Yosra Al-Hindi, Amal Al-sulami, Aseel Al-ghamdi, Nuha Al-Harbi, Huda Hamdi , Shooq Al-moqati, Yara Abualkair and Arwa Fairaq  

June 2020

Haematology, serum biochemistry and histopathological findings associated with sub-chronic administration of methanol leaf extract of Pterocarpus santalinoides DC in albino rats

The effects of sub-chronic administration of Pterocarpus santalinoides methanol leaf extract (PSME) on haematology, serum biochemistry and histology of albino rats were evaluated. Twenty female albino rats, randomly assigned into four groups (A-D) of five rats each, were used for the study. Groups A-C were treated orally with 500, 250 and 50 mg/kg PSME, respectively, while Group D was given distilled water as placebo at...

Author(s): Thelma Ebele Ihedioha, Isaac Uzoma Asuzu, Aruh Ottah Anaga and John Ikechukwu Ihedioha