African Journal of
Pharmacy and Pharmacology

  • Abbreviation: Afr. J. Pharm. Pharmacol.
  • Language: English
  • ISSN: 1996-0816
  • DOI: 10.5897/AJPP
  • Start Year: 2007
  • Published Articles: 2142

Table of Content: 8 August, 2015; 9(29)

August 2015

Properties of constituents from Maytenus gonoclada against Entamoeba histolytica and two leukemia cell strains

Species of genus Maytenus represents promising sources of bioactive compounds, mainly pentacyclic triterpenes of medicinal interest. The properties of crude extracts and three known triterpenes obtained from branches and roots of Maytenus gonoclada, against Entamoeba histolytica and human promyelocytic leukemia HL-60 (myeloid leukemia), and Jurkat (lymphocytic leukemia) cells were in vitro evaluated. For crude extracts,...

Author(s): Thaisa H. S. Fonseca, Fernando C. Silva, Haendel G. N. O. Busatti, Michelle O. Chacon, Carla R. A. Batista, Caryne M. Bertollo, Elaine M. Souza-Fagundes, Sidney A. Vieira-Filho, Lucienir P. Duarte and Maria A. Gomes

August 2015

Evaluation of curcumin toxicity in rats through biochemical and hematological parameters

Curcumin is a natural compound known for hepatic and nephroprotective actions, however, there is little research related to its possible side effects. The research aimed to study hematological, biochemical parameters and histopathology of hepatic and renal tissues to evaluate the effects of curcumin toxicity in male rats. A group of Wistar male rats (n = 10) was orally treated for five days with 100 mg/kg of curcumin...

Author(s): Ketllyn S. Voncik, Raissa H. de Mattos, Weber C. F. N. da Silva, Guilherme B. L. de Freitas, Timothy G. Cavazzatto, João B. T. da Rocha, Najeh M. Khalil and Juliana S. Bonini

August 2015

Effects of aqueous root bark extract of Citropsis articulata (Swingle & Kellerman) on sexual function in male rats

About 80% of the world’s population uses herbal medicine for the treatment of various health conditions. Erectile dysfunction is one of the conditions commonly treated using traditional herbs on large scale.  In this study, our goal was to determine the safety and effects of the aqueous root bark extract of Citropsis articulata on sexual function in male Wistar rats. This study aimed to carry out...

Author(s): Joseph Oloro, Paul E. Alele, Martin Amanya, Julius K. Tanayen, Joseph O. Chukwujekwu Ezeonwumelu, and Amon G. Agaba