African Journal of
Pharmacy and Pharmacology

  • Abbreviation: Afr. J. Pharm. Pharmacol.
  • Language: English
  • ISSN: 1996-0816
  • DOI: 10.5897/AJPP
  • Start Year: 2007
  • Published Articles: 2184

Table of Content: 8 February 2014; 8(5)

February 2014

Phytochemical screening, gas chromatography-mass spectrometry (GC-MS) analysis of phytochemical constituents and anti-bacterial activity of Aerva lanata (L.) leaves

The present study is aimed to determine the phytochemical screening and anti-bacterial activity of the extracts (acetone, ethyl acetate and ethanol) of medicinal plant, Aerva lanata leaves against bacterial strains. Acetone, ethyl acetate and ethanol extracts of A. lanata leaves were prepared using Soxhlet apparatus. These extracts of A. lanata leaves were checked for their anti-bacterial activity by well diffusion,...

Author(s): Arun Thangavel , Senthilkumar Balakrishnan, Aarthy Arumugam, Senbagam Duraisamy and Sureshkumar Muthusamy

February 2014

Evaluation of antioxidant capacity of the aqueous extract of Cynara scolymus L. (Asteraceae) in vitro and in Saccharomyces cerevisiae

The present study evaluated the antioxidant capacity of the aqueous extract of the leaves of Cynara scolymus on Saccharomyces cerevisiae strains, proficient and deficient in antioxidant defenses, and by in vitro methods with 1,1-diphenyl-2-picrylhydrazyl (DPPH•), 2,2'-azinobis-3-ethylbenzothiazoline-6-sulfonic acid (ABTS•+), inhibition of hydrogen peroxide, lipid peroxidation, formation of nitric oxide,...

Author(s): George Laylson da Silva Oliveira, Francisco Rodrigo de Asevedo Mendes de Oliveira, Marcus Vinícius Oliveira Barros de Alencar, Antonio Luiz Gomes Junior, Alexandre Araujo de Souza, Ana Amélia de Carvalho Melo Cavalcante and Rivelilson Mendes de Freitas

February 2014

Effects of volatile oils of the Microlobius foetidus on trypsin, chymotrypsin and acetylcholinesterase activities in Aedes aegypti (Diptera: Culicidae)

Volatile oils of Microlobius foetidus were used for the evaluation of mortality, trypsin, chymotrypsin and acetylcholine inhibition and Aedes aegypti morphology. Bioassays were made with different concentrations (25, 50 and 100 μg/ml) and alterations in the gut of 4th stage larvae were observed. Volatile oils affected larvae in all stages, with 100% mortality for the 100 μg/ml concentration (LD50 >33.02). The...

Author(s): Cristiane B. da Silva, Luciane Dalarmi, Josiane F. G. Dias, Sandra M.W. Zanin,  Katlin S. Rech, Juliana D. Kulik, Vitor A. Kerber, Euclésio Simionatto, Nilva Ré- Poppi, Sâmya S. Gebara, Obúlio G.Miguel and Marlis D. Miguel

February 2014

Evaluation of activity exerted by a steroid derivative on injury by ischaemia/reperfusion

There are reports which indicate that some steroid derivatives have activity atcardiovascular level; nevertheless, there is scarce information about the effects exerted by the progesterone derivatives on cardiac injury caused by ischemia/reperfusion. In this study, a new steroid (progesterone derivative) was synthetized with the objective of evaluating its activity on ischemia/reperfusion injury. The Langendorff...

Author(s): Lauro Figueroa-Valverde, Francisco Díaz-Cedillo, Marcela Rosas-Nexticapa, ElodiaGarcía-Cervera, Eduardo Pool-Gómez, Maria López-Ramos, Betty Sarabia-Alcocer and Isamar Damian-Hernandez

February 2014

Evaluation of clarity and consistency in dosing directions and measuring devices for pediatric over the counter liquid medications used in United Arab Emirates

The aim of this study was to evaluate the clarity and consistency prevalent in dosing directions and measuring devices used for over the counter (OTC) liquid pediatric medications available in United Arab Emirates (UAE). 130 pediatric oral liquid OTC medications with dosing information for children younger than 12 years were studied. The study specifically focused on issues like the inclusion of a measuring device,...

Author(s): Nazima Abdulrazaq, Areeg Anwer Ali, Mahmoud Mowloud, Dima Hamada and Umar Quraishi