September 2019

Canvassing of biological attributes by In vitro screening of Canarium bengalense

Various Hoang family remedies known as Dai-Thien-Nuong, utilize Canarium bengalense Roxb. (Family: Burseraceae) as a major component for the treatment of tumor and liver damage. This study was performed using the crude methanol extract of C. bengalense Roxb. bark and its petroleum ether, carbon tetrachloride, dichloromethane and aqueous soluble fractions for antioxidant, cytotoxic, thrombolytic, membrane stabilizing and...

Author(s):  Sanjina Saif Karim, Quazi Sufia Islam and Tasnuva Sharmin  

September 2019

Tolerance and observance of methotrexate in the treatment of rheumatoid arthritis at the university Hospital Bogodogo, Burkina Faso

This study is aimed at assessing tolerance and observance of the patients with RA (rheumatoid arthritis) treated by methotrexate at University Hospital Bogodogo, in Burkina Faso. A cross-sectional study was conducted from July to September 2015 in outpatients with rheumatoid arthritis monitored in rheumatology service. Data were obtained from interview, by reviewing medical cards of the patients and consultation report...

Author(s): R. Frank E. Zongo, Joelle S. Zabsonré, Aminata Nacoulma, Souleymane Fofana, Moise W. Sawadogo, Estelle Noella Youl, Moussa Ouédraogo, and Dieu-Donné Ouédraogo,  

September 2019

Use of medicinal plants for the treatment of gastric ulcer in some parts of Southwestern Nigeria

Ulcer is erosion in the lining of the stomach or duodenum. It is caused by disruption of the gastric mucosal defense and repair systems. There has been much interest in natural medicines derived from traditional knowledge of pharmacological properties of plants recently. The major aim of this study was to conduct an ethnobotanical survey of plants used in the treatment of Gastric ulcers in some local government areas of...

Author(s): Idayat A. Akinwumi and Mubo A. Sonibare  

September 2019

Effects of methanolic tuber extract of Cyperus esculentus Linn (tiger nuts) on sub-acute liver damage in albino rats

This study evaluated the effects of Cyperus esculentus methanolic tuber extract (CEME) on carbon tetrachloride (CCl4)-induced sub-acute liver damage in albino rats. Dried tubers of C. esculentus were pulverized and extracted by cold maceration, using 80% methanol. Thirty albino rats, randomly assigned to 6 groups (A–F) of 5 each were used for the study. Sub-acute liver damage was induced in Groups A-E rats using...

Author(s): Thelma Ebele Ihedioha, Rita Ifeoma Odo, Uwakwe Simon Onoja, Chinweike Emmanuel Chiwetalu and John Ikechukwu Ihedioha  

September 2019

24 h pre-incubation of EA.hy926 cells with angiotensin II regulates insulin-dependent activation of eNOS in a concentration-dependent manner

The rennin-angiotensin II system (RAS) and the insulin-PI3kinase signalling pathways cross-interact with important physiological and pathophysiological consequences for cells and the whole organism. Here, the effect of 24 h pre-incubation of EA.hy926 with two different concentrations of angiotensin II, on insulin-mediated activation of the PI3kinase-AKT-eNOS signalling was investigated. Quiescent EA.hy926 cells were...

Author(s): Ejebe D. E.