Journal of
Medicinal Plants Research

  • Abbreviation: J. Med. Plants Res.
  • Language: English
  • ISSN: 1996-0875
  • DOI: 10.5897/JMPR
  • Start Year: 2007
  • Published Articles: 3812

Full Length Research Paper

Improvement of the antioxidant activity of apigenin in linoleic acid system by o-prenylation

Benguo Liu1, Jiguo Yang2*, Xiaoai Zhu1 and Guibao Lv1
1School of Food Science, Henan Institute of Science and Technology, Xinxiang 453003, China. 2College of Light Industry and Food Science, South China University of Technology, Guangzhou 510640, China.
Email: [email protected]

  •  Accepted: 28 February 2011
  •  Published: 31 January 2012


With apigenin as raw material, 5-prenyloxy apigenin was synthesized and identified by high performance liquid chromatography - ultra violet - electrospray ionization tandem/ mass spectrometry (HPLC-UV-ESI/MS). And its antioxidant activity in linoleic acid system was superior to that of apigenin, which could support our hypothesis about antioxidant function regions of flavonoids.


Key words: Apigenin, o-prenylation, antioxidant, high performance liquid chromatography electrospray ionization tandem mass spectrometry (HPLC-ESI/MS).