Journal of
Medicinal Plants Research

  • Abbreviation: J. Med. Plants Res.
  • Language: English
  • ISSN: 1996-0875
  • DOI: 10.5897/JMPR
  • Start Year: 2007
  • Published Articles: 3835

Full Length Research Paper

In vivo study of antiplasmodium and histological activity of Garcinia kola and Aloe vera extracts against falciparum malaria

Onyinyechi Cecilia Amobi-Alor
  • Onyinyechi Cecilia Amobi-Alor
  • Department of Biological Sciences, Godfrey Okoye University, P.M.B. 01014, Enugu, Nigeria.
  • Google Scholar
Adanna Cynthia Eze
  • Adanna Cynthia Eze
  • Department of Biological Sciences, Godfrey Okoye University, P.M.B. 01014, Enugu, Nigeria.
  • Google Scholar
Chineye Lucy Ugwute
  • Chineye Lucy Ugwute
  • Department of Biological Sciences, Godfrey Okoye University, P.M.B. 01014, Enugu, Nigeria.
  • Google Scholar
Nneka Mariam Unachukwu
  • Nneka Mariam Unachukwu
  • Department of Biological Sciences, Godfrey Okoye University, P.M.B. 01014, Enugu, Nigeria.
  • Google Scholar
Chika Udeh
  • Chika Udeh
  • Department of Biological Sciences, Godfrey Okoye University, P.M.B. 01014, Enugu, Nigeria.
  • Google Scholar
Simeon Okolo
  • Simeon Okolo
  • Department of Biological Sciences, Godfrey Okoye University, P.M.B. 01014, Enugu, Nigeria.
  • Google Scholar
Chidimma Claribel Chikezie
  • Chidimma Claribel Chikezie
  • Department of Biological Sciences, Godfrey Okoye University, P.M.B. 01014, Enugu, Nigeria.
  • Google Scholar
Kelechi Mbah-Omeje
  • Kelechi Mbah-Omeje
  • Department of Applied Microbiology and Brewing, Enugu State University of Science and Technology, Enugu, Nigeria.
  • Google Scholar
Felix Chukwuebuka Onyia
  • Felix Chukwuebuka Onyia
  • Department of Biological Sciences, Godfrey Okoye University, P.M.B. 01014, Enugu, Nigeria.
  • Google Scholar


  •  Received: 14 June 2020
  •  Accepted: 24 November 2020
  •  Published: 31 May 2021

References

Adaramoye O, Akinpelu T, Kosoko A, Okorie P, Kehinde A, Falade C, Ademowo O (2014). Antimalarial potential of kolaviron, a biflavonoid from Garcinia kola seeds against Plasmodium berghei infection in Swiss albino mice. Asian Pacific Journal of Tropical Medicine 7(2):97-104.
Crossref

 

Adegboye MF, Akinpelu DA, Okoh AI (2008). The bioactive and phytochemical properties of Garcinia kola (Heckel) seed extract on some pathogens. African Journal of Biotechnology 7(21):3934-3938.

 

Airaodion AI, Ekenjoku JA, Ngwogu KO, Ngwogu AC (2020). Ethanolic extract of Garcinia kola (Heckel) seed possesses antiplasmodialproperties against Plasmodium berghei. Asian Journal of Medical Principles and Clinical Practice 3(1):33-39.

 

Baird JK, Caneta-Miguel E, Masba S, Bustos DG, Abrenica JA, Layawen AV, Calulut JM, Leksana B, Wignall FS (1996). Survey of resistance to chloroquine of falciparum and vivax malaria in Palawan, The Philippines. Transactions of the Royal society of Tropical Medical Hygiene 90:413-414.
Crossref

 

Damian DC, Nweze EI, Onyeke CC (2017). The In vivo anti-plasmodium activity of Garcinia kola Heckel. Journal of BasicPharmacology and Toxicology 1(2):27-31.

 

European Medicine Agency (EMEA) (2013). Quality of Herbal Medicinal Products. Guidelines. European Agency for the Evaluation of Medicinal Products (EMEA), London.

 

Hay SI, Guerra CA, Tatem AJ, Noor AM, Snow RW (2004). The global distribution and population at risk of malaria: past, present and future. Lancet Infectious Diseases 4:327-336.
Crossref

 

Koshy AS, Anila L, Vijayalakshmi NR (2001). Flavonoids from Garcinia cambogia lower lipid levels in hypercholesterolemic rats. Food and Chemical Toxicology 72(3):289-294.
Crossref

 

Matotoka MM, Masoko P (2018). Phytochemical screening and pharmacological evaluation of herbal concoctions sold at Ga Maja Limpopo Province. South African Journal of Botany 117:1-10
Crossref

 

Ndukwe KC, Okeke IN, Lamikanra A, Adesina SK, Aboderin OJ (2005). Antibacterial activities of aqueous extracts of selected chewing sticks. Journal of Contemporary Dental Practice 6(3):86-94.
Crossref

 

Nwaokorie, F., Coker, A., Akitoye, C. Folasade, O., Gaetti-Jardim, E., Oyedele, G., Ayanbadejo, P., Abdurrazag, T. and Umezudike, A. (2010). Antimicrobial activity of Garcinia kola on oral Fusobacterium nucleatum and biofilm. African Journal of Microbiological Research, 4(7):509- 514.

 

Rowe AK, Rowe SY, Snow RW, Korenromp EL, Armstrong JR, Stein C, Nahlen BL, Bryce J, Black R, Steketee RW (2006). The burden of malaria mortality among African children in the year 2000. International Journal of Epidemiology 35(3):691-704.
Crossref

 

Surjushe A, Vasani R, Saple DG (2008). Aloe vera: A short review. Indian Journal of Dermatology 53(4):163-166.
Crossref

 

Thompson PE, Werbel LM (1972). Antimalarial agents: chemistry and pharmacology. In: de Stevens G, editor. Medicinal chemistry, Academic Press, Inc. New York

 

World Health Organization (2010). Basic malaria microscopy: part I. Learner's guide, second edition, WHO Press, World Health Organization, Geneva, Switzerland P 75.

 

World Malaria Report (2005). Information available to WHO and UNICEF at the end of 2004.