Journal of
Toxicology and Environmental Health Sciences

  • Abbreviation: J. Toxicol. Environ. Health Sci.
  • Language: English
  • ISSN: 2006-9820
  • DOI: 10.5897/JTEHS
  • Start Year: 2009
  • Published Articles: 208

Full Length Research Paper

Cadmium toxicity exposure – Induced oxidative stress in postnatal development of Wistar rats

P. Dailiah Roopha1, J. Savarimuthu Michael2, C. Padmalatha1 and A. J. A. Ranjit Singh2*
1Department of Advanced Zoology and Biotechnology, Rani Anna Government College for Women, Tirunelveli-627 008, Tamil Nadu, India. 2Department of Advanced Zoology and Biotechnology, Sri Paramakalyani College, Alwarkurichi-627 412, Tamil Nadu, India.
Email: [email protected]

  •  Accepted: 02 December 2010
  •  Published: 31 July 2011

Abstract

Effect of cadmium on ovary increased reactive oxygen species (ROS) was studied in rat. Lipid peroxidation and the reactive oxygen species, hydrogen peroxide were increased in the ovary of Wistar rat administered with cadmium (50 and 200 ppm) in drinking water on 45 and 65 days of post natal development. Elevation of reactive oxygen species and lipid peroxidation is suggestive of tissue damage in the rat ovary due to cadmium poisoning.

 

Key words: Cadmium, lipid peroxidation, reactive oxygen species, hydrogen peroxide ovary.