Journal of
Toxicology and Environmental Health Sciences

  • Abbreviation: J. Toxicol. Environ. Health Sci.
  • Language: English
  • ISSN: 2006-9820
  • DOI: 10.5897/JTEHS
  • Start Year: 2009
  • Published Articles: 208

Full Length Research Paper

L-Theanine: Neuroprotective Against Trichloroethylene-induced Parkinson’s Disease Hallmarks

Justin Shen
  • Justin Shen
  • Jericho Senior High School, Jericho, New York.
  • Google Scholar


  •  Received: 20 July 2020
  •  Accepted: 11 August 2020
  •  Published: 31 August 2020

References

Ball N, Teo W, Chandra S, Chapman J (2019). Parkinson's Disease and the Environment. Frontiers in Neurology, Volume 10.
Crossref

 

Ben P, Zhang Z, Xuan C, Sun S, Shen L, Gao Y, Cao X, Zhou Y, Lan L, Yin Z, Luo L (2015). Protective Effect of l-Theanine on Cadmium-Induced Apoptosis in PC12 Cells by Inhibiting the Mitochondria-Mediated Pathway. Neurochemical Research 40(8): 1661-1670.
Crossref

 

Bonvallot N, Harrison P, Loh M (2010). WHO guidelines for indoor air quality: Selected pollutants. Copenhagen: WHO.

 

Braak H, Rüb U, Gai WP, Tredici KD (2003). Idiopathic Parkinson's disease: Possible routes by which vulnerable neuronal types may be subject to neuroinvasion by an unknown pathogen. Journal of Neural Transmission 110(5): 517-536.
Crossref

 

Braak H, Tredici KD, Rüb U, Vos RA, Steur EN, Braak E (2003). Staging of brain pathology related to sporadic Parkinson's disease. Neurobiology of Aging 24(2): 197-211.
Crossref

 

Brookes PS, Yoon Y, Robotham JL, Anders MW, Sheu S (2004). Calcium, ATP, and ROS: A mitochondrial love-hate triangle. American Journal of Physiology-Cell Physiology 287:4.
Crossref

 

Catalá A, Díaz M (2016). Editorial: Impact of Lipid Peroxidation on the Physiology and Pathophysiology of Cell Membranes. Frontiers in Physiology, Volume 7. 
Crossref

 

Chan FK, Moriwaki K, Rosa MJ (2013). Detection of Necrosis by Release of Lactate Dehydrogenase Activity. Methods in Molecular Biology Immune Homeostasis pp. 65-70.
Crossref

 

Channel SR, Latendresse JR, Kidney JK, Grabau JH, Lane JW, Steel-Goodwin L, Gothaus MC (1998). A Subchronic Exposure to Trichloroethylene Causes Lipid Peroxidation and Hepatocellular Proliferation in Male B6C3F1 Mouse Liver. Toxicological Sciences 43(2):145-154.
Crossref

 

Chatterjee S, Chatterjee A, Roy S, Bera B, Bandyopadhyay SK (2014). L-Theanine healed NSAID-induced gastric ulcer by modulating pro/antioxidant balance in gastric ulcer margin. Journal of Natural Medicines 68(4):699-708.
Crossref

 

Chen S, Wang Z, Ma Y, Zhang W, Lu J, Liang Y, Zheng X (2018). Neuroprotective Effects and Mechanisms of Tea Bioactive Components in Neurodegenerative Diseases. Molecules 23(3):512.
Crossref

 

Cheng H, Ulane CM, Burke RE (2010). Clinical progression in Parkinson disease and the neurobiology of axons. Annals of Neurology 67(6):715-725.
Crossref

 

Cho H, Kim S, Lee S, Park JA, Kim S, Chun HS (2008). Protective effect of the green tea component, l-theanine on environmental toxins-induced neuronal cell death. NeuroToxicology 29(4):656-662.
Crossref

 

Deb S, Dutta A, Phukan BC, Manivasagam T, Thenmozhi AJ, Bhattacharya P, Borah A (2019). Neuroprotective attributes of L-theanine, a bioactive amino acid of tea, and its potential role in Parkinson's disease therapeutics. Neurochemistry International 129:104478.
Crossref

 

DeMaagd G, Phillip A (2015). Parkinson's Disease and Its Management. Pharmacy and Therapeutics 40(8): 504-510.

 

Doherty RE (2000). A History of the Production and Use of Carbon Tetrachloride, Tetrachloroethylene, Trichloroethylene and 1,1,1-Trichloroethane in the United States: Part 2--Trichloroethylene and 1,1,1-Trichloroethane. Environmental Forensics 1(2):83-93.
Crossref

 

Emamzadeh FN, Surguchov A (2018). Parkinson's Disease: Biomarkers, Treatment, and Risk Factors. Frontiers in Neuroscience P. 12.
Crossref

 

Gash DM, Rutland K, Hudson NL, Sullivan PG, Bing G, Cass WA, Prince TS (2008). Trichloroethylene: Parkinsonism and complex 1 mitochondrial neurotoxicity. Annals of Neurology 63(2):184-192.
Crossref

 

Goldman SM (2010). Trichloroethylene and Parkinson's disease: Dissolving the puzzle. Expert Review of Neurotherapeutics 10(6):835-837.
Crossref

 

Guehl D, Bezard E, Dovero S, Boraud T, Bioulac B, Gross C (1999). Trichloroethylene and parkinsonism: A human and experimental observation. European Journal of Neurology 6(5):609-611.
Crossref

 

Inamdar N, Arulmozhi D, Tandon A, Bodhankar S (2007). Parkinsons Disease: Genetics and Beyond. Current Neuropharmacology 5(2):99-113.
Crossref

 

Khare S, Gokulan K, Williams K, Bai S, Gilbert KM, Blossom SJ (2018). Irreversible effects of trichloroethylene on the gut microbial community and gut-associated immune responses in autoimmune-prone mice. Journal of Applied Toxicology 39(2):209-220.
Crossref

 

Krasnic T (2017). Preliminary Information on Manufacturing, Processing, Distribution, Use, and Disposal: Trichloroethylene [PDF]. United States Environmental Protection Agency.

 

Li C, Tong H, Yan Q, Tang S, Han X, Xiao W, Tan Z (2016). L-Theanine Improves Immunity by Altering TH2/TH1 Cytokine Balance, Brain Neurotransmitters, and Expression of Phospholipase C in Rat Hearts. Medical Science Monitor 22:662-669.
Crossref

 

Liu M, Choi D, Hunter RL, Pandya JD, Cass WA, Sullivan PG, Bing G (2010). Trichloroethylene induces dopaminergic neurodegeneration in Fisher 344 rats. Journal of Neurochemistry 112(3):773-783.
Crossref

 

Mahajan SD, Law W, Aalinkeel R, Reynolds J, Nair BB, Yong K, Schwartz SA (2012). Nanoparticle-Mediated Targeted Delivery of Antiretrovirals to the Brain. Methods in Enzymology Nanomedicine - Infectious Diseases, Immunotherapy, Diagnostics, Antifibrotics, Toxicology and Gene Medicine pp. 41-60.
Crossref

 

Muñoz E, Pastor P, Martí MJ, Valldeoriola F, Tolosa E, Oliva R (2001). Enfermedad de Parkinson esporádica y familiar: Estudio comparativo. Medicina Clínica 116(16):601-604.
Crossref

 

Nango H, Kosuge Y, Miyagishi H, Sugawa K, Ito Y, Ishige K (2017). Prostaglandin E2 facilitates neurite outgrowth in a motor neuron-like cell line, NSC-34. Journal of Pharmacological Sciences 135(2):64-71.
Crossref

 

Rietdijk CD, Perez-Pardo P, Garssen J, Wezel RJ, Kraneveld AD (2017). Exploring Braak's Hypothesis of Parkinson's Disease. Frontiers in Neurology P. 8.
Crossref

 

Russell HH, Matthews JE, Sewell GW (1992). TCE Removal from Contaminated Soil and Ground Water [PDF]. United States Environmental Protection Agency.

 

Saqcena M, Menon D, Patel D, Mukhopadhyay S, Chow V, Foster DA (2013). Amino Acids and mTOR Mediate Distinct Metabolic Checkpoints in Mammalian G1 Cell Cycle. PLoS ONE 8:8.
Crossref

 

Sharma N, Nehru B (2017). Curcumin affords neuroprotection and inhibits α-synuclein aggregation in lipopolysaccharide-induced Parkinson's disease model. Inflammopharmacology 26(2):349-360.
Crossref

 

Sharma RK, Candelario-Jalil E, Feineis D, Bringmann G, Fiebich BL, Akundi RS (2017). 1-Trichloromethyl-1,2,3,4-tetrahydro-beta-carboline (TaClo) Alters Cell Cycle Progression in Human Neuroblastoma Cell Lines. Neurotoxicity Research 32(4):649-660.
Crossref

 

Sugiyama T, Sadzuka Y, Tanaka K, Sonobe T (2001). Inhibition of glutamate transporter by theanine enhances the therapeutic efficacy of doxorubicin. Toxicology Letters 121(2):89-96.
Crossref

 

Thangarajan S, Deivasigamani A, Natarajan SS, Krishnan P, Mohanan SK (2014). Neuroprotective activity of L-theanine on 3-nitropropionic acid-induced neurotoxicity in rat striatum. International Journal of Neuroscience 124(9):673-684.
Crossref

 

Triarhou LC (2013). Dopamine and Parkinson's Disease. Austin, Texas: Landes Bioscience.

 

Yokogoshi H, Terashima T (2000). Effect of theanine, r-glutamylethylamide, on brain monoamines, striatal dopamine release and some kinds of behavior in rats. Nutrition 16(9):776-777.
Crossref

 

Yulug B, Ozansoy M, Cankaya S (2019). A different view on the pathophysiology of Parkinson's disease: A descendent neurochemical hypothesis? Neural Regeneration Research 14(10):1717.
Crossref

 

Zaheer F, Slevin JT (2011). Trichloroethylene and Parkinson Disease. Neurologic Clinics 29(3):657-665.
Crossref

 

Zhu Q, Shen T, Ding R, Liang Z, Zhang X (2005). Cytotoxicity of trichloroethylene and perchloroethylene on normal human epidermal keratinocytes and protective role of Vitamin E. Toxicology 209(1):55-67.
Crossref

 

Ziv I, Zilkha-Falb R, Offen D, Shirvan A, Barzilai A, Melamed E (1997). Levodopa induces apoptosis in cultured neuronal cells-A possible accelerator of nigrostriatal degeneration in Parkinson's disease? Movement Disorders 12(1):17-23.
Crossref