African Journal of
Biotechnology

  • Abbreviation: Afr. J. Biotechnol.
  • Language: English
  • ISSN: 1684-5315
  • DOI: 10.5897/AJB
  • Start Year: 2002
  • Published Articles: 12227

Full Length Research Paper

In vitro evaluation of roots, seeds and leaves of Sesamum indicum L. for their potential antibacterial and antioxidant properties

Sandhya Sharma
  • Sandhya Sharma
  • Department of Bioscience and Biotechnology, Banasthali University, Banasthali- 304022 (Rajasthan), India.
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Priti Gupta
  • Priti Gupta
  • Department of Bioscience and Biotechnology, Banasthali University, Banasthali- 304022 (Rajasthan), India.
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Ashwani Kumar
  • Ashwani Kumar
  • Department of Botany, Ch. Charan Singh P.G. College, Heonra (Saifai), Etawah-206130 (UP), India.
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Jaswant Ray
  • Jaswant Ray
  • Department of Zoology, Mewar University, Rajasthan, India.
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Bipin Kumar Aggarwal
  • Bipin Kumar Aggarwal
  • Department of Zoology, Mewar University, Rajasthan, India.
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Pankaj Goyal
  • Pankaj Goyal
  • Department of Microbiology, Gurukul Kangri University, Hardwar (Uttarakhand), India.
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Anubhuti Sharma*
  • Anubhuti Sharma*
  • Department of Biochemistry, Vivekananda Parvatiya Krishi Anusandhan Sansthan (ICAR), Almora, India.
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  •  Received: 02 April 2014
  •  Accepted: 14 July 2014
  •  Published: 03 September 2014

Abstract

It is important to exemplify different types of medicinal plants for their potential antioxidant and antimicrobial properties as it has been evident that diverse nutrient and non-nutrient molecules which are produced from aromatic and medicinal plants display antioxidant and antimicrobial properties, and can protect human body against cellular oxidation reaction and pathogens. Methanol and aqueous extracts of different parts (seeds, roots and leaves) of Sesamum indicum L. were screened to detect in vitro antioxidant [1,1-diphenyl-2-picryl hydrazyl (DPPH) and thiobarbituric acid (TBA)] and antimicrobial (disc diffusion and deep well diffusion) activity. On the basis of the results, different parts of S. indicum L. showed promising antimicrobial and antioxidant activity in methanol extract instead of aqueous extracts. It has also been observed that S. indicum L. has a powerful antioxidant and antimicrobial activity and can be used as accessible source of natural antioxidants and antimicrobial agent in pharmaceutical industry and as a possible food supplement.

Key words: Sesamum indicum L., 1, 1-diphenyl-2-picryl hydrazyl (DPPH), thiobarbituric acid (TBA), antioxidant, antimicrobial.