African Journal of
Biotechnology

  • Abbreviation: Afr. J. Biotechnol.
  • Language: English
  • ISSN: 1684-5315
  • DOI: 10.5897/AJB
  • Start Year: 2002
  • Published Articles: 12487

Full Length Research Paper

Co-expressing house fly cytochrome P450 6A1 and human cytochrome P450 reductase in Escherichia coli to bioconvert insecticide aldrin

Yating Wu
  • Yating Wu
  • Hubei Provincial Key Laboratory for Protection and Application of Special Plants in Wuling Area of China, College of Life Science, South Central University for Nationalities, Wuhan 430074, PR China.
  • Google Scholar
Yong Li
  • Yong Li
  • Hubei Provincial Key Laboratory for Protection and Application of Special Plants in Wuling Area of China, College of Life Science, South Central University for Nationalities, Wuhan 430074, PR China.
  • Google Scholar
Xiaosheng Liang
  • Xiaosheng Liang
  • Hubei Provincial Key Laboratory for Protection and Application of Special Plants in Wuling Area of China, College of Life Science, South Central University for Nationalities, Wuhan 430074, PR China.
  • Google Scholar
Nan Jiang
  • Nan Jiang
  • Hubei Provincial Key Laboratory for Protection and Application of Special Plants in Wuling Area of China, College of Life Science, South Central University for Nationalities, Wuhan 430074, PR China.
  • Google Scholar
Yunhua Wu
  • Yunhua Wu
  • Hubei Provincial Key Laboratory for Protection and Application of Special Plants in Wuling Area of China, College of Life Science, South Central University for Nationalities, Wuhan 430074, PR China.
  • Google Scholar


  •  Received: 26 April 2018
  •  Accepted: 27 July 2018
  •  Published: 15 August 2018

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Wiseman A, Lewis DFV (2007). 57-Isoform cytochromes P450 for bioconversions. Enzyme and Microbial Technology 40:1469-1474.
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Wu YH (2011). Direct electrochemistry of cytochrome P450 6A1 in mimic bio-membrane and its application for pesticides sensing, Sensors and Actuators B. Chemical 156:773-778.
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Xiao PF, Mori T, Kamei I, Kiyota H, Takagi K, Kondo R (2011). Novel metabolic pathways of organochlorine pesticides dieldrin and aldrin by the white rot fungi of the genus Phlebia. Chemosphere 85:218-224.
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Zhang L, Liu XQ, Wang CT, Liu, XQ, Cheng, G, Wu YH (2010). Expression, purification and direct eletrochemistry of cytochrome P450 6A1 from the house fly, Musca domestica. Protein Expression and Purification 71:74-78.
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Zhang XY, Wang JX, Liu J, Li YH, Liu XJ, Wu HH, Ma E, Zhang JZ (2017). Knockdown of NADPH-cytochrome P450 reductase increases the susceptibility to carbaryl in the migratory locust, Locusta migratoria. Chemosphere 188:517-524.
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