African Journal of
Microbiology Research

  • Abbreviation: Afr. J. Microbiol. Res.
  • Language: English
  • ISSN: 1996-0808
  • DOI: 10.5897/AJMR
  • Start Year: 2007
  • Published Articles: 5093

Full Length Research Paper

Antimicrobial resistance pattern of Acinetobacter spp. isolated from clinical samples in a tertiary care hospital at Madinah, Saudi Arabia

Samah Ghanem
  • Samah Ghanem
  • Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, Taibah University, Madinah, P. O. Box 3893, Kingdom of Saudi Arabia.
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Hatem M. El Shafey
  • Hatem M. El Shafey
  • Department of Respiratory Therapy, College of Medical Rehabilitation Sciences, Taibah University, P. O. Box 3893 Madinah, Kingdom of Saudi Arabia.
  • Google Scholar
Nikhat Manzoor
  • Nikhat Manzoor
  • Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, Taibah University, Madinah, P. O. Box 3893, Kingdom of Saudi Arabia.
  • Google Scholar


  •  Received: 23 May 2018
  •  Accepted: 31 July 2018
  •  Published: 14 August 2018

Abstract

Multidrug resistance, in rapidly spreading bacterial species, is a matter of concern in health care units. Samples (6840) collected from a Saudi hospital in Madinah, were screened for Acinetobacter spp. and studied for frequency, gender distribution, and seasonal variations besides antimicrobial resistance pattern. Acinetobacter strains represented 5.5% of the clinical isolates from different sources. Of these, 63% were recovered from male samples. The largest numbers of these organisms were isolated from sputum and wound swabs representing about 85% of the samples. Antimicrobial sensitivity pattern showed that colistin was the most effective drug since it inhibited 76% of the Acinetobacter isolates. The remaining drugs did not reveal sensitivity greater than 15%. Results suggest colistin to be a promising drug in the treatment of Acinetobacter infections. It was also observed that percentage of these infections was highest during summers representing 39.15%, followed by autumn (28.17%) and winters (26.48%), while spring season recorded the least percentage with only 6.2% of infections. The present study was an attempt to generate data on the prevalence of resistance pattern and management of Acinetobacter infections.

 

Key words: Acinetobacter, antimicrobial sensitivity pattern, multidrug resistance, nosocomial infections.