African Journal of
Microbiology Research

  • Abbreviation: Afr. J. Microbiol. Res.
  • Language: English
  • ISSN: 1996-0808
  • DOI: 10.5897/AJMR
  • Start Year: 2007
  • Published Articles: 5233

Full Length Research Paper

Evaluation of gene xpert assay and microscopic examination for detection of Mycobacterium tuberculosis in sputum at Port Harcourt, Nigeria

Confidence Kinikanwo Wachukwu
  • Confidence Kinikanwo Wachukwu
  • Department of Medical Laboratory Science, Rivers State University, Nkpolu-Oroworukwo, Port Harcourt, Rivers State, Nigeria.
  • Google Scholar
Stella Paulinus Okwelle
  • Stella Paulinus Okwelle
  • Department of Medical Microbiology, University of Port Harcourt Teaching Hospital, Choba, Rivers State, Nigeria.
  • Google Scholar
Easter Godwin Nwokah
  • Easter Godwin Nwokah
  • Department of Medical Laboratory Science, Rivers State University, Nkpolu-Oroworukwo, Port Harcourt, Rivers State, Nigeria.
  • Google Scholar
Ollor Amba Ollor
  • Ollor Amba Ollor
  • Department of Medical Laboratory Science, Rivers State University, Nkpolu-Oroworukwo, Port Harcourt, Rivers State, Nigeria.
  • Google Scholar


  •  Received: 25 August 2017
  •  Accepted: 14 December 2017
  •  Published: 14 April 2018

References

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Boehme CC, Sutherland R (2009). Xpert, MTB/RIF Demonstrations for detection of TB and Rifampicin resistance. 

 

Daniel WW (1999). Biostatistics, A foundation for analysis in the Health Sciences. (7th edition), New York: John Willey and Sons. 35-40.

 

Dolin F, Gerald L, Mandell E (2010). Principles and practice of infectious diseases. J. Infect. Dis. 250: 1124-1130.

 

Fred T (2009). Two-hour detection of MTB and resistance to rifampicin. Invitro diagnostic medical device. Diseases and Project-Tuberculosis-Xpert MTB/RIF Review A, 4300-7810 (Accessed 20/7/2015).

 

Grant LR (2012). Procedures for collection of induced sputum specimen from children. Clinic. Infect. Dis. Oxf. J. 54:140-145.

 

Issar S (2003). Mycobacterium tuberculosis pathogenesis and molecular determinants of virulence. Clinic. Microbiol. Rev. 16(3):463-496.
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Lalloo G, Naidoo R, Ambaram A (2006). Recent advances in the medical and surgical treatment of multi-drug resistant tuberculosis. Curre. Opini. Pulmon. Medic. 12:179-185.
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Palomino JC, Martin A, Portcels F (2007). Rapid drug resistance in Mycobaterium tuberculosis. Clinc. Microbio. Infect. 13:754-762.
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Ritu S, Vithal PM (2015). Microscopy as a diagnostic tool in pulmonary tuberculosis. Intern. J. Mycobact. 4(1):1-5.
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Scott LE, McCarthy K, Gous N, Nduna M, Van Rie A, Sanne I, Venter WF, Duse A, Stevens W (2011). Comparisons of Xpert MTB/RIG with other nucleic acid technologies for diagnosing pulmonary tuberculosis in a high HIV prevalence setting: A prospective study. J. Pub Medi. 8(7):1371-1379.

 

Small PM, Pai M (2010). Tuberculosis diagnosis – Time for a game change. New Engl. J. Med. 363:1070-1071.
Crossref

 

Van Rie A, Page-Shipp L, Scott L, Sanne I. Stevens W (2010). Expert MTB/RIF for point-of-care diagnosis of TB in high HIV burden, resource-limited countries: hype or hope? Exp. Rev. Molec. Diagn. 10:937-946.
Crossref

 

World Health Organization (2013). Updated WHO Recommendation for Diagnosis of Pulmonary TB, and Pediatric TB, Extra Pulmonary TB and Rifampicin resistance. 

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