African Journal of
Microbiology Research

  • Abbreviation: Afr. J. Microbiol. Res.
  • Language: English
  • ISSN: 1996-0808
  • DOI: 10.5897/AJMR
  • Start Year: 2007
  • Published Articles: 5233

Full Length Research Paper

Interactive effect of Zeralenone and Fumonisin B1 on caspace-3 kinetic activity, lactate dehydrogenase leakage, malondialdehyde levels and viability in Caco-2 cells

James H. Kouadio*
  • James H. Kouadio*
  • Department of Biochemistry and Microbiology, University of DALOA (UJLoG), BP 150, Cote d?Ivoire
  • Google Scholar
Serge Moukha
  • Serge Moukha
  • INRA, Centre de Recherches de Bordeaux Aquitaine, UPR 1264- MycSA, P.O. Box 81, 33883 Villenave d?Ornon, France
  • Google Scholar
Brou Kouakou
  • Brou Kouakou
  • Department of Nutrition and Food Safety, University of Nangui-Abrogoua, 02 BP 802, Abidjan Cote d?Ivoire
  • Google Scholar
Amani Georges
  • Amani Georges
  • Department of Nutrition and Food Safety, University of Nangui-Abrogoua, 02 BP 802, Abidjan Cote d?Ivoire
  • Google Scholar


  •  Received: 02 May 2014
  •  Accepted: 12 September 2014
  •  Published: 24 September 2014

References

Abado-Bécognée K, Mobio TA, Ennamany R, Fleurat-Lessart F, Shier WT, Badria F Creppy EE (1998). Cytotoxicity of fumonisin B1/implication of lipid peroxidation and inhibition of protein and DNA syntheses. Arch. Toxicol. 72:233-236.
Crossref

 

Abid-Essefi S, Ouanes Z, Hassen W, Baudrimont I, Creppy EE, Bacha H (2003). Cytotoxicity, inhibition of DNA and Protein syntheses and oxydative damage in cultured cells exposed to zearalenone.Toxicol. In vitro. 192:237-248.
Crossref

 
 

Ayed-Boussema I, Bouaziz C, Rjiba K, Valenti K, Laporte F, Bacha H, Hassen W (2008). The mycotoxin Zearalenone induces apoptosis in human hepatocytes (HepG2) via p53-dependent mitochondrial signaling pathway. Toxicol. in Vitro 22:1671-1680.
Crossref

 
 

Babich H, Borenfreund E (1987). Fathead minnow FHM cells for use in in vitro cytotoxicity assays of aquatic pollutants. Ecotoxicol. Environ. Saf. 14:78-87.
Crossref

 
 

Bezuidenhout SC, Gelderblom WCA, Gorst-Allman CP, Horak RM, Marasas WFO, Spiteller G, Vleggaar RR (1988). Structure elucidation of the fumonisins, mycotoxins from Fusarium moniliforme. J. Chem. Soc., Chem. Commun. 11:743-745.
Crossref

 
 

Boeira LS, Bryce JH, Stewart GG, Flannigan B (2000). The effect of combinations of Fusarium mycotoxins (deoxynivalenol, zearalenon and fumonisin B1) on growth of brewing yeasts. J. Appl. Microbiol. 88:388-403.
Crossref

 
 

Bouaziz C, Sharaf El Dein O, El Golli E, Abid-Essefi S, Brenner C, Lemaire C, Bacha H (2008). Different apoptotic pathways induced by zearalenone, T-2 toxin and ochratoxin A in human hepatoma cells. Toxicology 254:19-28.
Crossref

 
 

Bradford MM (1976). A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72:248-254.
Crossref

 
 

Chu FS, Li GY (1994). Simultaneous occurrence of fumonisin B1 and other mycotoxins in moldy corn collected from the People's Republic of China in regions with high incidences of esophageal cancer. Appl. Environ. Microbiol. 60:847-852.
Pubmed

 
 

Creppy EE (2002). Update of survey, regulation and toxic effects of mycotoxins in Europe. Toxicol. Lett. 127:19-28.
Crossref

 
 

Dawlatana M, Coker RD, Nagler MJ, Wild CP, Hassan MS, Bluden G (2002). The occurrence of mycotoxins in key commodities in Bengladesh: surveillance results from 1993 to 1995. J. Nat. Toxins 11:379-86.
Pubmed

 
 

Desjardins AE, Manandhar G, Platttner RD, Maragos CM, Shrestha K, McCormick SP (2000). Occurrence of Fusarium species and mycotoxin in neplaese maize and wheat and the effect of traditional processinr methods on mycotoxin levels. J. Agric. Food Chem. 48:1377-1383.
Crossref

 
 

Di Pietro A, Vries EG, Gietema JA, Spierings DC, De Jong S (2005). Testicular germ cell tumours: the paradigm of chemo-sensitive solid tumours. Int. J. Biochem. Cell Biol. 37:2437-2456.
Crossref

 
 

Dutton MF (1996). Fumonisins, mycotoxins of increasing importance: Their nature and their effects. Pharmacol. Theorapeutics. 70:137-161.
Crossref

 
 

Ennamany R, Marzetto S, Saboureau D, Creppy EE (1995). Lipid peroxidation induced by Noletu satanas: implicationin m5dC variation in Vero cells related to inhibitin of cells growth. Cell Biol. Toxicol. 11:347-54.
Crossref

 
 

Etienne M, Dourmad Y (1994). Effects of zearalenone or glucosinolates in the diet on reproduction in sows: a review. Livest. Prod. Sci. 40:99-113.
Crossref

 
 

Fotakis G, Timbrell JA (2006). In vitro cytotoxicity assays: Comparison of LDH, neutral red, MTT and protein assay in hepatoma cell lines following exposure to cadmium chloride. Toxicol. Lett. 160:171-177.
Crossref

 
 

Galluzzi L, Aaronson SA, Abrams J, Alnemri ES, Andrews DW, Baehrecke EH, Bazan NG, Blagosklonny MV, Blomgren K, Borner C, Bredesen DE, Brenner C, Castedo M, Cidlowski JA, Ciechanover A, Cohen GM, De Laurenzi V, De Maria R, Deshmukh M, Dynlacht BD, El-Deiry WS, Flavell RA, Fulda S, Garrido C, Golstein P, Gougeon ML, Green DR, Gronemeyer H, Hajnóczky G, Hardwick JM, Hengartner MO, Ichijo H, Jäättelä M, Kepp O, Kimchi A, Klionsky DJ, Knight RA, Kornbluth S, Kumar S, Levine B, Lipton SA, Lugli E, Madeo F, Malomi W, Marine JC, Martin SJ, Medema JP, Mehlen P, Melino G, Moll UM, Morselli E, Nagata S, Nicholson DW, Nicotera P, Nu-ez G, Oren M, Penninger J, Pervaiz S, Peter ME, Piacentini M, Prehn JH, Puthalakath H, Rabinovich GA, Rizzuto R, Rodrigues CM, Rubinsztein DC, Rudel T, Scorrano L, Simon HU, Steller H, Tschopp J, Tsujimoto Y, Vandenabeele P, Vitale I, Vousden KH, Youle RJ, Yuan J, Zhivotovsky B, Kroemer G (2009). Guidelines for the use and interpretation of assays for monitoring cell death in higher eukaryotes. Cell Death Differ. 16:1093-1107.
Crossref

 
 

Gopee NV, Sharma RP (2004). The mycotoxin fumonisin B1 transiently activates nuclear factor-kappaB, tumor necrosis factor alpha and caspase 3 via protein kinase Calpha-dependent pathway in porcine renal epithelial cells. Cell Biol. Toxicol. 20:197-212.
Crossref

 
 

Hassen W, Ayed-Boussema I, Oscoz AA, Lopez Ade C, Bacha H (2007). The role of oxidative stress in zearalenone-mediated toxicity in Hep G2 cells: oxidative DNA damage, gluthatione depletion and stress proteins induction. Toxicology 232:294-302.
Crossref

 
 

Hendricks K (1999). Fumonisins and neural tube defects in South Texas. Epidemiology 10:198-200.
Pubmed

 
 

Kouadio JH, Dano DS, Moukha S, Mobio TH, Creppy EE (2007). Effets of combination of Fusarium mycotoxins (deoxynivalenol, zearalenone and fumonisin B1) on Caco-2 cells viability, inhibition of macromolecules syntheses, malonaldehyde level and DNA methylation and fragmentation. Toxicon 49:306-317.
Crossref

 
 

Kouadio JH, Mobio TH, Baudrimont I, Moukha S, Dano DS, Creppy EE (2005). Comparative study of cytoxicity and oxidative stress induce by deoxynivalenol, zearalenone of fumonisin B1 in Human intestinal cell line Caco-2. Toxicology 213:56-65.
Crossref

 
 

Kuiper-Goodman T, Scott PM, Watanabe H (1987). Risk assessment of the mycotoxin zearalenone. Regulat. Toxicol. Pharmacol. 7:253-306.
Crossref

 
 

Marasas WF, Riley RT, Hendricks KA, Stevens VL, Sadler TW, Gelineau-Vanwaes J, Missmer SA, Cabrera J, Torres O, Gelderblom, WC, Allegood J, Martinez C, Maddox J, Miller JD, Starr L, Sullards MC, Roman AV, Voss KA, Wang E, Merrill AH (2004). Fumonisins disrupt sphingolipid metabolism, folate transport, and neural tube development in embryo culture and in vivo: a potential risk factor for human neural tube defects among populations consuming fumonisin-contaminated maize. J. Nutr. 134:711-716.
Pubmed

 
 

Mobio TA, Tavan E, Baudrimont I, Anane R, Carratu MR, Sanni A, Gbeassor MF, Shier TW, Narbonne JF, Creppy EE (2003). Comparative study of the toxic effects of fumonisin B1 in rat C6 glioma cells and p53-null mouse embryo fibroblasts. Toxicology 183:65-75.
Crossref

 
 

National Toxicology Program (NTP) (1982). Carcinogenesis Bioassay of Zearalenone in F 344/N Rats and F6C3F1 Mice (Technical Report Series No. 235), Research Triangle Park, North Carolina: Department of Health and Human Services, NTP North Carolina.

 
 

Ouanes Z, Ayed-Boussema I, Baati T, Creppy EE, Bacha H (2005). Zearalenone induces chromosome aberrations in mouse bone marrow: preventive effect of 17beta-estradiol, progesterone and Vitamin E. Mutat Res. 565:139-149.
Crossref

 
 

Rheeder JP, Marasas WFO, Thiel PG, Sydenham EW, Shephard GS, Van Schalkwyk DJ (1992). Fusarium moniliforme and fumonisins in corn in relation to human oesophageal cancer in Transkei. Phytopathology 82:353-57.
Crossref

 
 

Rousset M, Laburthe M, Pinto M, Chevalier G, Rouyer-Fessard C, Dussaulx E, Trugnan G, Boige N, Brun JL Zweibaum A (1985). Enterocytic differentiation and glucose utilisation in the human colon tumour cell line Caco-2: modulation by forskolin. J. Cell. Physiol. 123:377-385.
Crossref

 
 

Sangare-Tigori B, Moukha S, Kouadio HJ, Betbeder AM, Dano DS, Creppy EE (2006). Co-occurrence of aflatoxin B1, fumonisin B1, ochratoxin A and zearalenone incereals and peanuts from Cote d'Ivoire. Food Addit. Contam. 23:1000-1007.
Crossref

 
 

Scudamore KA, Livesey CT (1998). Occurence and Significance of mycotoxins in forage crops and silage: a review. J. Sci. Food Agric. 77:1-17.
Crossref

 
 

Seefelder W, Humpf HV, Schwerdt G, Freudinger R, Gekle M (2003). Induction of apoptosis in cultured human proximal tubule cells by fumoninsins and fumonisins metabolites. Toxicol. Appl. Pharmacol. 1634:40-51.

 
 

Shier WT, Shier AC, Xie X, Mirocha CJ (2001). Structure-activity relationships for human oestrogenic activity in zearalenone mycotoxins. Toxicon 39:1435-1438.
Crossref

 
 

Smith SM, Wunder MB, Norris DA, Shellman YG (2011). A Simple Protocol for Using a LDH-Based Cytotoxicity Assay to Assess the Effects of Death and Growth Inhibition at the Same Time. PLoS ONE 6(11):e26908.
Crossref

 
 

Soriano JM, Gonzalez L, Catala AI (2005). Mechanism of action of sphingolipids and their metabolites in the toxicity of fumonisin B1. Prog. Lipid Res. 44:345-356.
Crossref

 
 

Sydenham EW, Thiel PG, Marasas WFO, Shephard GS, Van Schalkwyk DJ, Koch KR (1990). Natural occurrence of some Fusarium mycotoxins in corn from low and high esophageal cancer prevalence in areas of the Transkei, Southern Africa. J. Agric. Food Chem. 38:190-203.
Crossref

 
 

Wyllie AH, Kerr JF, Currie AR (1980). Cell death: the significance of apoptosis. Int. Rev. Cytol. 68:251-306.
Crossref

 
 

Yusup A, Upur H, Baudrimont I, Umar A, Kader T, Begaud B, Creppy EE, Moore N (2005). Cytotoxicity of abnormal Savda Munziq aqueous extract in human hepatoma (HepG2) cells. Fundam. Clin. Pharmacol. 19:465-72.
Crossref

 
 

Yu JY, Zheng ZH, Son YO, Shib X, Jang YO, Lee JC (2011). Mycotoxin zearalenone induces AIF- and ROS-mediated cell death through p53- and MAPK-dependent signaling pathways in RAW264.7 macrophages. Toxicol. In Vitro 25:1654-1663
Crossref

 
 

Zinedine A, Soriano J-M, Molto JC, Man J (2007). Review on the toxicity, occurrence, metabolism, detoxification, regulations and intake of zearalenone: an oestrogenic mycotoxin. Food Chem. Toxicol. 45:1-18.
Crossref