Formulation and evaluation of gastro-retentive floating tablets of griseofulvin
June 2022 - Vol 16 Num. 6
About 50% of an oral dose of griseofulvin passes through the gastro-intestinal tract unabsorbed and is excreted in faeces. Short residence time of the low soluble griseofulvin, in stomach and small intestine, limits its dissolution. Griseofulvin is highly soluble in acidic pH, and so a gastro-retentive floating...
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