Factors influencing the increase in the choice of nursing as career among students at the Department of Nursing, Njala University, Bo District, Southern Sierra Leone
July 2023
This study assessed the factors influencing the increase in the choice of nursing as career among students at the Department of Nursing, Njala University, Bo District. It adopted a descriptive research design to collect data on a sample size of 96 students. Data was collected the Career Search Questionnaire and was analyzed using descriptive statistics (frequencies, percentages, etc.) and inferential statistics...
Post stroke special clinic in primary care: How well the patients with stroke can be managed in the community?
July 2023
Optimal control of modifiable cardiovascular disease risk factors for patients with stroke is essential to prevent further ischemic events. The aim of this study was to evaluate the performance of the Post-Stroke Special Clinic (PSSC), a public primary care setting run by family specialists, by testing the control of blood pressure, low density lipoprotein, haemoglobin A1c if diabetic and smoking, among patients who had...
Electrocardiogram parameters in patients with hypertensive heart failure in Abakaliki, South-Eastern Nigeria
May 2021
Hypertension and Hypertensive Heart Failure (HHF) constitutes a growing burden of non-communicable forms of cardiovascular disease (CVD) in Africa. This work was designed to investigate Electrocardiogram (ECG) parameters in HHF subjects. A cross-sectional study involving 100 subjects of equal number of HHF and normal subjects were used. Questionnaires were administered; socio-demographic and medical profiles of the...
Choice of contraceptives and determinants influencing utilization among women: The case of Muk-Lami town, western Wollega zone of Oromia Regional State, Ethiopia
August 2019
This study was conducted in Muk-Lami town located at 498 km from Addis Ababa and 54 km far from the Western Wollega zonal city, Ghimbi. The study was concerned with reproductive health and contraception where females in the study area have less exposure to contraceptives, choice and proper utilization of methods. This study attempted to investigate major determinants of contraceptive choice, use and side effects on...
Knowledge, attitudes and perceived barriers to post-operative pain management: Institution based cross sectional study
August 2017
Post-operative pain is a common problem after surgical procedure. Undertreated and uncontrolled post-operative pain reduce physical and social performance, impaired quality of life and patient dissatisfaction, delayed discharge, increased use of health care resources and high cost on their hospital stay. Even if the problem is vast, researches on the area lack adequate data. This study aimed to assess knowledge,...
Predictors of postoperative sore throat among surgical patients at Ethiopian teaching hospitals
November 2016
Post-operative sore throat significantly impact patients’ satisfaction during post-operative period. Many factors can contribute to postoperative sore throat and the incidence varies with the method of airway management. To determine the predictors and incidence of postoperative sore throat. In this facility based cross sectional study, 245 elective gynecologic and general surgical patients who had had surgery at...
Decrease in expression of some proteins among breast cancer patients in Sudan comparison to healthy tissues
August 2015
Breast cancer is one of the most common cancers in women, and rated the second most common cancer and a significant cause of death in females in the Sudan. This study aims to identify tumor protein that elicits humoral immune responses in breast cancer patient in comparison to tissues from healthy individuals as well as from normal tissues of the cancer patient. Serum samples and breast cancer tissue specimens were...
Treatment of recurrent refractory mantle cell lymphoma by thalidomide in combination with interferon
April 2015
Mantle cell lymphoma (MCL) is a highly aggressive non-Hodgkin's lymphoma with poor prognosis. This study aims to explore a new, safe approach for patients with recurrent refractory MCL. A total of six patients with recurrent refractory MCL were recruited. They all accepted thalidomide tablets (100 mg/day) orally every night, accompanied with interferon α-2b (3 million units, injected subcutaneously) every...
Mental health problems of street children in residential care in Zambia: Special focus on prediction of psychiatric conditions in street children
March 2015
This study aims to find out mental health problems and examine their role in prediction of psychiatric conditions in street children in residential care. Five (5) street children residential centres in Lusaka District, as well as a cross-section of street children (74) in residential care aged between 7 and 17 years were used for this study. Overall, 74 (68 males and 6 females) children in residential care were at risk...
Vaginal colonization and resistance profile of group B Streptococcus among pregnant women in Yaoundé Gynecology, Obstetric and Pediatric Hospital in Cameroon
November 2014
In order to obtain reliable data on vaginal carriage of Streptococcus agalactiae in pregnant women and to formulate a prevention program of neonatal Group B Streptococcus (GBS) disease, we carried out a prospective cross sectional study for 6 months. The general objective of the study was to evaluate the prevalence of vaginal carriage and the resistance profile of GBS. The study involved 142 pregnant women presenting...
Using of hemofiltercytological blood test to monitor the quality of patients radically operated on for colorectal cancer adjuvant chemotherapy
June 2014
Application of hemofiltercytological analysis shows its ample opportunities in assessment of polychemotherapy completeness and quality through the study of drug pathomorphosis. The objective of the study was development and studying of the clinical relevance of hemofiltercytological venous blood test as completeness and quality control of patients with colorectal cancer adjuvant chemotherapy. 35 of 39 tested cancer...
Comparative in vitro potency of four fluoroquinolones on clinical isolates over a year period
January 2014
This study aimed at evaluating the efficacy of four common fluoroquinolone drugs over a year period on some clinical isolates. It also aimed at comparing statistically the average effects of each drug on the isolates. Five different clinical samples (urine, sputum, wound, blood and high vaginal swab [HVS]) from patients attending a university medical centre (between June 2011 and May 2012) were analysed for the purpose...
Epistaxis in Kaduna, Nigeria: A review of 101 cases in a resource constrained setting
January 2014
Epistaxis is defined as hemorrhage from the nostril, nasal cavity, or nasopharynx. Sufferers and clinicians may develop significant anxiety despite the fact that majority of patients may be treated successfully by the first attending physician. The objective of this study was to review the incidence, common etiological factors and management modalities of epistaxis in a resource constrained setting. It is a...
A study investigating infant and young child feeding practices in Foni Kansala district, western region, Gambia
October 2013
It has been documented and a well-established fact that good nutrition including appropriate infant and young child feeding practices is central to the growth and development of all infants and young children. A study to investigate infant and young child feeding practices was conducted in Foni Kansala District, The Republic of The Gambia. The overall aim of the study was to explore the situation of infant and young...
Is delayed coagulopathy still difficult to anticipate after snakebite? — An illustrative case report
October 2013
Coagulopathy following snakebite typically occur within 24 h. Occasionally, abnormality of the coagulation system persists into the second week; although clinically, significant bleeding is rare after seven days. Early coagulopathy and concurrent acute renal failure tends to increase the odd of delayed coagulopathy. We report a case of delayed coagulopathy and renal failure occurring after 2 weeks in a previously...
A useful biomarker in talar osteochondral disease activity: Mean platelet volume (MPV)
August 2013
In order to test the role of platelet activation in the talar osteochondral disease, the mean platelet volume (MPV) in patients undergoing treatment of talar osteochondral disease was evaluated. White blood cell count and highly sensitive C-reactive protein were evaluated in 50 patients with osteochondral defect of talus. Disease activity was assessed according to American Orthopedic Foot and Ankle Society scoring....
Comparison of single-incision mid-urethral tape (Ophiraâ„¢) and transobturator tape (Obtryxâ„¢) sub-urethral sling procedures for female stress urinary incontinence
August 2013
This non-randomised study prospectively compared clinical efficacy and patient satisfaction of single-incision mid-urethral tape (Ophira™) against transobturator tape (Obtryx™). Objective cure rates were defined at 12 months follow-up as negative cough stress test and subjective cure was assessed by patient perception of improved symptoms, using the International Consultation on Incontinence Questionnaire...
Correlation between clinical and magnetic resonance imaging (MRI) findings in temporomandibular disorders
June 2013
This study was carried out to determine the value of Magnetic resonance imaging (MRI) as a diagnostic tool in patients with temporomandibular disorders. The clinical presentation and MRI findings on 88 temporomandibular joints belonging to 44 symptomatic patients were retrospectively studied. The disk position, configuration and signal intensity; mandibular condyle morphology and signal intensity; temporomandibular...
Anatomical study of the third head of biceps brachii muscle and its innervation by median nerve in human dissection
June 2013
Several studies have described the biceps brachii muscle as one of the muscles in the upper limb with most frequent anatomical variations. They also reported the presence of this anomaly in varying frequency in different populations. The aim of this study was to assess the anatomical description of the third head of biceps brachii muscle and its abnormal innervation in human autopsies which would be of value for the...
In vitro preventive effects of nitrate tolerance by a polyphenol-enriched extract of Hibiscus sabdariffa
March 2013
Treatment failure or tolerance, which rapidly leads to a reduced hemodynamic effects and therapeutic efficacy is the major limitation of long-term use of nitrates, including nitroglycerin (NTG) in the treatment of coronary artery disease. These effects are most often associated with oxidative stress. Thus, in this work, we were interested in the prevention of nitrate tolerance by the antioxidant compounds...
Coronary artery by pass grafting and lung lobectomy: Functional outcomes at discharge
March 2013
Mortality and complication rates after on-pump versus off-pump coronary artery bypass grafting (CABG), and open lung lobectomy (OL) versus video-assisted lobectomy (VAL), have previously been reported, but further research regarding functional outcomes is needed. This study compared functional recovery at discharge between patients who underwent on-pump versus off-pump CABG, and OL versus VAL. In patients discharged...
Revealing the effect of probiotic combination: Lactobacillus rhamnosus and Lactobacillus acidophilus (Lacidofil®) on acute diarrhea in adult patients
February 2013
The concept of taking probiotic supplementation for better health and improving acute episodes of diarrhea has been well-known. Several studies have indicated that probiotic supplementation bring beneficial effects for patients with diarrhea. However, there is a striking lack of evidence on the supplementation of probiotic products in adult patients with acute diarrhea and prescribing probiotics for acute diarrhea has...
Liquid nitrogen cryotherapy vs. Betamethasone lotion in the management of Alopecia areata
February 2013
Alopecia areata (AA) is a common disease of hair follicles. Cryotherapy has been employed to stimulate hair regrowth. We decided to evaluate the efficacy of this method in patchy AA. Forty patients of age >5 years and with 120 recalcitrant patches were enrolled in this study. AA had covered less than 25% of patients’ scalps. In each individual, one lesion was treated with nitrogen cryotherapy once weekly...
Oxidative stress in myocardial infarction: Advanced glycation end-products causes oxidative stress in older myocardial infarction patients
February 2013
Older patients with type 2 diabetes mellitus have a two- to four-fold increased risk of myocardial infarction. This study aims to determine the association between oxidative stress and advanced glycation end product (AGE). Human serum samples from normal older subjects (n = 31), older diabetic patients without myocardial infarction (n = 33), older diabetic patients with myocardial infarction (n = 32),...
Effect of water-depth on the antidepressant-like actions of furosemide
January 2013
Increase in water-depth increases the sensitivity of the forced swim test (FST) and it was deemed necessary to investigate the antidepressant-like activities of furosemide, bumetanide and nifedipine vis-à-vis the currently used antidepressants, imipramine and sertraline at different water-depths. Groups of mice with six mice each were divided into two batches of 10 groups for the experiments at the different...
Recovery of sertoli cells by Allium cepa in Toxoplasma gondii infected rats
January 2013
Toxoplasma gondii is a protozoan parasite that is globally widespread and it affects men and animals. We investigated the effect of allium cepa (onion juice) on sperm parameters, testestrone level in male rats was experimentally infected by T. gondii.Wistar male rats (n=40) were allocated into four groups: control group (n=10), T1 group that received tachyzoites of T. gondii (n=10),...
Correlation between clinical and magnetic resonance imaging (MRI) findings in temporomandibular disorders
December 2012
This study was carried out to determine the value of Magnetic resonance imaging (MRI) as a diagnostic tool in patients with temporomandibular disorders. The clinical presentation and MRI findings on 88 temporomandibular joints belonging to 44 symptomatic patients were retrospectively studied. The disk position, configuration and signal intensity; mandibular condyle morphology and signal intensity; temporomandibular...
Combined oral and vaginal misoprostol use in therapeutic terminations at 14 to 28 weeks of gestation
December 2012
This study involved an investigation of the effectiveness and complications of oral and vaginal misoprostol use on the termination of second trimester pregnancies. A total of 103 cases were recruited from the medical records of the Gynecology and Obstetrics Clinic of Taksim Research and Training Hospital and Şırnak İdil State Hospital. Women underwent therapeutic termination of pregnancy between the 14 to 28th...
Investigation of influence of inside out transobturator vaginal tape (TVT-O) procedure on objective, subjective cure rates and different quality of life tests in stress urinary incontinence treatment
November 2012
This study was aimed at Investigating the influence of the transobturator tape (TOT) procedure used in surgical treatment of stress urinary incontinence on objective and subjective cure rates, as well as quality of life. A total of 156 patients who were diagnosed as stress incontinence and mixed incontinence with stress predominancy, underwent a TOT operation under spinal anesthesia by one surgeon or two surgeons of the...
Relationship between blood pressure and arterial stiffness in patients undergoing antihypertensive treatment: A pilot study
November 2012
Mean arterial blood pressure is one of the principal modifiable factors which contribute to arterial stiffness. The influence of anti hypertensive drugs on arterial stiffness measured photoplethysmographically has not yet been studied. This pilot study was aimed at exploring the relationship between blood pressure (BP) and parameters of arterial stiffness on initiating antihypertensive treatment. Fourteen newly...
The effect of furosemide on experimentally-induced seizures in mice
October 2012
The aim of this study was to investigate the effect of the loop diuretic, furosemide, on maximal electroshock- and leptazol-induced seizures in mice. Mice were given furosemide, phenytoin and diazepam intraperitoneally and after 30 min they were challenged with maximal electroshock (MES) or leptazol. In MES, furosemide at doses of 25 and 50 mg/kg did not protect against hind limb tonic extension (HLTE) while phenytoin...
Body mass index (BMI) related insulin resistance in polycystic ovarian syndrome among patients referred to gynecology clinic of Imam Reza Hospital, Tehran, Iran
October 2012
Polycystic ovarian syndrome (PCOs) is one of the commonest endocrinopathies of women. The present work has been undertaken with an aim to study insulin resistance rate among army personnel families. Out of 108 women suffering from oligomenorrhea and hirsutism referred to gynecology clinic of Imam Reza hospital from 2009 to 2010, 58 patients with PCOs were evaluated for insulin resistance. Their disease was diagnosed...
Corneal biomechanical characteristics, intraocular pressure and central corneal thickness in patients with type 2 diabetes mellitus
July 2012
To evaluate corneal biomechanical properties, intraocular pressure and central corneal thickness in type 2 diabetic patients by Ocular Response Analyzer (ORA), ORA measurements were performed on the 80 eyes of 40 diabetic patients (group I) and 80 eyes of 40 healthy people who served as the control group (group II). Corneal hysteresis (CH), corneal resistance factor (CRF), intraocular pressure (Goldmann correlated...
Interesting case of coronary artery fistula and coronary anomaly resulting in coronary steal with literature review
July 2012
Coronary artery fistulae are rare and abnormal communications between a coronary artery and a great vessel, which may shunt blood flow away from the myocardial capillary network causing steal phenomenon. We present a 47-year-old man with a unique arteriovenous fistula originating from the proximal portion of the left main coronary artery and entire left anterior descending artery, which then reconstitutes to form a...
Distribution of SPV genes, plasmid profiles and pulsotypes of Salmonella enteritidis isolates of animal and human origins in selected locations of Zimbabwe
May 2012
A total of 49 Salmonella enteritidis isolates identified by culture and biochemical tests were confirmed using multiplex polymerase chain reaction (PCR). The isolates were grouped into two, those with Salmonella plasmid virulence (spv) gene and those without the spv gene. Plasmid and pulsed field gel electrophoresis (PFGE) analysis were performed on both groups. Of the 49 S....
Quality of life after septal surgery
May 2012
To assess the quality of life in patients who has been through the surgical intervention related to nasal septum in ENT department of Abbasi Shaheed Hospital, Karachi. This study was done from January 2008 to August 2008. Case based study, with post-interventional quality of life assessment questionnaire. One hundred patients undergoing nasal septum related surgery, after their full informed and written consent, were...
In vitro and in vivo evaluation of acetylsalicylic acid in Khat (Qat) chewing healthy volunteers
April 2012
Aspirin is being extensively used in Yemen as analgesic, antipyretic, anti-inflammatory and anti-platelets aggregation for prophylaxis of thrombotic heart diseases. The objective of this study was to evaluate 2 common brands of aspirin present in the market, weight variation, disintegration and dissolution, hardness and drug content and the effect of Khat chewing on their bioavailability. 28 healthy male volunteers (14...
A review of the types of presentation among positive angiographic acute coronary syndrome patients in Hospital Universiti Sains Malaysia
April 2012
Atypical presentation of myocardial infarction is recognized as an important manifestation of coronary heart disease associated with unfavorable prognosis. Understanding the spectrum of clinical symptoms and presentations are essential to diagnose and deliver appropriate rapid treatment to patients in the emergency department. Hence, this study was carried out to identify the type of presentation of acute coronary...
The p53 status in patients with common variable immunodeficiency
April 2012
Common variable immunodeficiency (CVID) comprises a heterogeneous group of primary antibody deficiencies with complex clinical and immunological phenotypes. A high risk for cancer has been described for some types of cancer among patients with CVID. Mutations in p53, a critical tumor suppressor gene, are one of the most common genetic alterations in human cancers, therefore contributes to the complex network of...
Management of snake bite in resource-challenged setting: A review of 18 months experience in a Nigerian hospital
March 2012
Snake bite is a worldwide environmental and occupational hazard with significant public health importance. The management of snake bites includes the use of specific anti-venom, use of clotting factors and tetanus prophylaxis. In many developing countries however, specific anti-venoms are not widely available and this might affect the outcome of patient management. The main objective of this work is to analyze the...
Patients disclosure in health plan: Quality of care and physician competence
February 2012
Medical error and tort reform have increasingly taken center stage in the health care debate in our region and all over the world. Patients, policy makers and health care professionals grapple with the striking prevalence and consequences of medical error, may result in patient injury from the health care providers. Fears of malpractice liability, difficulties in communicating with patients and their families,...
Collagen deposition and cellular viability among UVB irradiated human dermal fibroblasts treated by platelets
February 2012
Prolonged or repeated low energy ultraviolet B (UVB) irradiation that can inhibit fibroblast proliferation, collagen synthesis, and stimulate collagen degradation is basic concept of skin photo-aging. Recently, a study showed that human skin fibroblasts treated with platelets resulted in a significant higher proliferation rates compared to placebo. The effect of platelets in...
A review of the types of presentation among positive angiographic acute coronary syndrome patients in Hospital Universiti Sains Malaysia
February 2012
Atypical presentation of myocardial infarction is recognized as an important manifestation of coronary heart disease associated with unfavorable prognosis. Understanding the spectrum of clinical symptoms and presentations are essential to diagnose and deliver appropriate rapid treatment to patients in the...
Enterovirus outbreak among preterm infants in Singapore General Hospital: Level II nursery Tan, Mary Grace S. and Yeo, Cheo Lian
January 2012
To describe the demographic characteristics, clinical presentations and outcome of neonatal enterovirus infection and to evaluate infection control measures effective in preventing the spread of infection. Detailed perinatal history, demography, neonatal conditions and laboratory investigations were retrieved retrospectively from 5 Enterovirus positive patients in the level II nursery of the Singapore General Hospital...
Calculated free testosterone in hemodialysis and renal transplanted men: Comparison of three equations with each other and with free androgen index
January 2012
Free testosterone has been shown to correlate better with androgen status than total testosterone. Assessment of free testosterone level has been recommended by all consensus best practice guidelines; however, its direct measurement is laborious and out of the scope of most clinical service laboratories. Calculating its level using some equations has been advocated in the absence of a direct measuring method. Androgen...
The effect of insulin therapy and plasma glucose levels on corrected QT intervals in patients with type 2 diabetes
January 2012
This study aims is to investigate the effect of medium-term insulin therapy (3 months) and plasma glucose levels on corrected QT intervals (QTc) in patients with type 2 diabetes. The subjects were 17 patients with type 2 diabetes who had poor glycemic control and were changed to insulin therapy from sulfonylurea or diet therapy alone. QTc, fasting plasma glucose (FPG), hemoglobin A1c (HbA1c), serum potassium and body...
The serum levels of P-cresol and Indoxyl sulfate in different hemodialysis vintage
December 2011
Indoxyl sulfate (IS) and para-cresol (p-cresol) belong to the group of protein-bound uremic toxins that are poorly cleared by dialysis and are associated with poor clinical outcomes. The goal of our study was to evaluate the relationship between dialysis time and serum levels of IS and p-cresol in hemodialysis (HD) patients. Our study enrolled 96 stable HD patients who were categorized into 8 subgroups on the basis...
Clinical investigation of neonatal jaundice
December 2011
Serum bilirubin levels of 93 neonates aged between 0 and 14 days were estimated. The bilirubin levels were determined spectrophotometrically at 570 nm (Direct) and 540 nm (Total) at the pediatric unit, Usmanu Danfodiyo University Teaching Hospital (UDUTH), Sokoto, Nigeria using continuous sampling techniques. It was established that the number of neonates with hyperbilirubinemia decreased with age. The mean...
Haemolytic uraemic syndrome associated with Klebsiella empyema-case report and literature review
December 2011
We report a 13 month old male with haemolytic uraemic syndrome (HUS) associated with Klebsiella empyema. He presented with fever, gastroenteritis and respiratory distress. Investigations showed left pleural effusion, and HUS. Blood and pleural exudate cultures grew Klebsiella pneumoniae. He died during chest tube insertion. Post mortem showed fibrinous empyema. Renal histology confirmed HUS. Klebsiella has not been...
Chronic idiopathic polyneuropathy: Patients’ own perception of well-being in correlation to clinical condition
November 2011
Chronic idiopathic polyneuropathy (CIP) is a disease of the elderly where further follow-up is usually not indicated after diagnosis. The aim of the study was to evaluate the self-reported functioning and well-being in patients with CIP in correlation to clinical findings. We examined forty-eight patients with CIP. The Fatigue Severity Scale, Visual Analogue Scale for pain, Disability Rating Index, Berg Balance...
Page 1 of 3, showing 50 records out of 106 total, starting on record 1, ending on 50
