Journal of
Toxicology and Environmental Health Sciences

  • Abbreviation: J. Toxicol. Environ. Health Sci.
  • Language: English
  • ISSN: 2006-9820
  • DOI: 10.5897/JTEHS
  • Start Year: 2009

JTEHS Articles

November 2018

Human kidney injury molecule-1 and interleukin-18 as predictive markers of nephrotoxicity in acute organophosphorus poisoned patients in Zagazig University hospitals

Organophosphorus (OP) poisoning is a major common cause of mortality and morbidity in most countries. Some clinical cases developed renal injury after acute OP poisoning. The aim of our study is to evaluate the levels of kidney injury molecule-1(KIM-1) and interleukin -18(IL-18) in acute OP poisoned patients as early predictors of OP induced nephrotoxicity. Over a period of one year, the observational cross sectional...

Author(s): Arwa A. El-Sheikh, Eman El-Sayed Khayal and Reem Allam  

November 2018

Influence of dry erase ink solvent mixtures on eye irritation

Teaching is the process of imparting knowledge by teachers in learners. To enhance this, methods of presenting information visually to a full room of students at once are used. This includes writing on whiteboards written using whiteboard marker pens. Dry erase ink for whiteboard marker pen is composed of volatile solvent vehicle which easily vaporizes allowing the mark to dry on the surface of the whiteboard. Different...

Author(s): Sabina Muthoni Muchemi, Wilkister Nyaora Moturi, George Morara Ogendi  

July 2018

The amelorative effect of L-arginin and omega-3 fatty acid against sodium valproate induced hepatotoxicity

Sodium valproate (VPA) used in epilepsy and has hepatotoxic effect in mammals. This work is to assess the role of L-arginin and omega-3 fatty acid against VPA oxidative stress on liver. This study was carried out on 70 rats divided into 7 groups each of 10 rats treated orally once daily 6days/ week; Group I (control), Group II ( L-arginin): each rat was received 300 mg/kg L-arginin, Group III (omega-3): each rat...

Author(s): Dalia M. Amin, Marwa T. Abaza, Walaa M. Sarhaan, Amany I. Ahmed, Amr A. Moustafa  

June 2018

Biochemical analysis and toxicity studies of some heavy metals and their correlation with different diseases

The problem of heavy metal toxicity is a burning issue all over the world and more prominent in countries like Pakistan, India and Bangladesh. Often times, it is seen that the people of the affected areas are unaware of the toxic effects of these metals. Medical practitioners at the same time did not investigate the presence of heavy metals in the body. The present study aims to analyze the concentration of toxic heavy...

Author(s): Muhammad Jahangir, Hafiz Muhammad Faizan Haider, Zafar Niaz, Sajid Abaidullal and Dawood Ilyas Minhas

May 2018

Organochlorine pesticides contamination in human milk in Abidan (Côte d’Ivoire)

Organochlorine pesticides belong to the class of persistent organic pollutants (POPs). They are deeply involved in environmental issues and represent a real threat for human health. The aim of this study was to assess the level of organochlorine pesticides contamination in human milk through two studies of POPs biomonitoring performed in 2010 and 2015 in Côte d'Ivoire. Primiparous breastfeeding mothers...

Author(s): Manda Pierre,  Adepo Aholia Jean-Baptiste and Dano Djédjé Sébastien

April 2018

Novel expression of the biomarker, Nε-hexanoyl lysine in gibberellic acid induced bone toxicity in adult albino rats

Plants hormones are widely used in agriculture to alter plant characteristics as growth regulators. Gibberellic acid (GA3) plays important role in promoting plant growth, and cell differentiation. This work was performed to investigate the relationship between lipooxidative damage marker (HEL) and bone damage induced by GA3 in adult albino rats. This study was carried out on 20 adult albino rats for 4 weeks treated 6...

Author(s): Dalia M. Amin, Aisha A. Abohashem, Ola A. Harb, Walaa M. Sarhan and Marwa A. Shabana

December 2017

Effects of contaminated natural soil by Glyphosan SL on biochemical responses of the earthworm Eisenia sp.

Biochemical biomarkers are widely used for the monitoring environmental quality since they can act as early warning signals, for potential ecosystem degradation caused by contaminants. In order to investigate the acute and chronic effects of a commercial formulation of glyphosate on antioxidant defenses (glutathione peroxidase, GPx; glutathione-S-transferase, GST; and reduced glutathione, GSH) and oxidative damage...

Author(s): Leida Marcano, Juanny Hernández, Edgar Zapata-Vívenes and Analía León

November 2017

Hematotoxicity status of lead and three other heavy metals in cow slaughtered for human consumption in Jos, Nigeria

Heavy metals are of public health concern worldwide due to their damaging effects on human and animal health, the environment and life in general. This study assessed concentration levels of some toxic heavy metals: Cadmium (Cd), lead (Pb), copper (Cu) and magnesium (Mg) in blood samples of ten (10) cattle slaughtered in two areas (Jos North and South) of Plateau State, Northern Nigeria. The results were compared with...

Author(s): Lucky Legbosi Nwidu and Temitayo Lucia Ohemu

October 2017

Lactate and creatine phosphokinase as potential independent predictors of organophosphrus poisoning severity in Zagazig University Hospital Patients, Egypt

This study aimed to assess the correlation of serum lactate and creatine phosphokinase (CPK) levels, and their association with severity of organophosphrus poisoning in order to use one of them or both as tools in predicting prognosis. This study was conducted over one year and 68 organophosphate (OP)-poisoned patients were enrolled. Clinical severity of cases was categorized according to Peradeniya organophosphorus...

Author(s): Manar H. Arafa, Nashwa M. Shalaby and Hebatallah H. Atteia

July 2017

Investigation of possible human exposure to metals concentration in vegetables

This study assesses the health risk of metals concentration in spinach and onions obtained from different suppliers (suppliers 1, 2, 3, 4 and 5) in Mafikeng, South Africa. The following elemental concentrations of As, Ba, Bi, Cu, Cr, Co, I, Mn, Ni, Pb, Sr, Th, Rb, V and U were tested in spinach and onions using inductively coupled plasma–mass spectrometry (ICP-MS). The result shows that Bi, I, Th, Pb and U were...

Author(s): Hilma Rantilla Amwele, Lebogang Motsei, Gideon Kalumbu, Nnenesi Kgabi, Raymond Limen Njinga, and Victor Makondelele Tshivhase

June 2017

Analysis of the incidence of the deficit of sanitation on the health of the populations in a context of urban growth: Case of the municipalities Yopougon, Abobo and Treichville' (Abidjan, Ivory Coast)

The emergence of pathologies and their impacts on the health of the populations were studied in the municipalities of Yopougon, Abobo, and Treichville. This study highlights the conditions of noxious life and the health of the populations. To achieve this, a transverse investigation with the households was conducted on 300 households in 2013. It is concerned with the sources of water supply. It was noticed that 80% of...

Author(s): Yapo Toussaint Wolfgang, , Amin N’cho Christophe, Yapo Ossey Bernard, and Mambo Veronique

June 2017

Maternal and foetal toxicity induced by exposure to mixture of dimethoate and cypermethrin in albino rats

The use of pesticide mixture to combat increased resistance by pest, to single chemical insecticide has brought about an increase in the use of pesticide mixture from different class, with its attendant toxicity. The objective of this study was to evaluate the maternal and foetal toxicity associated with dimethoate and cypermethrin, the two insecticides that are normally mixed to reduce pest resistance. 100...

Author(s): S. B. Ramon-Yusuf, Y. O. Aliu, O. A. Salawu, I. Chahoud and S. F. Ambali

May 2017

Biosorption of heavy metals onto different eco-friendly substrates

Fungi play an important role in biosorption of heavy metals in heavily contaminated soil. Five metals-tolerant fungal species were isolated from two different contaminated soil (soils 1 and 2). The number of fungal colonies isolated from the contaminated soil 2 was higher than that of soil 1. The most resistant fungal species for the toxic studied metals (Pb, Cd, Cu and Zn) was Rhizopus stolonifier followed by...

Author(s): Eman M. Fawzy, Fatma F. Abdel-Motaal and Soad A. El-zayat

May 2017

Evaluation of occupational exposure to metal dust on the liver of road construction workers in Abuja metropolis

Increasing air pollution levels due to rapid urbanization and growth in infrastructural facilities coupled with low level of standard safety procedures have been observed in Nigeria, and become a major source of concern. The study evaluated the effects of occupational exposure to metal dust on the liver of road construction workers in Abuja metropolis. Blood samples were used in the measurement of Lead, cadmium,...

Author(s): Ojevwe, D. D. and Osadolor, H. B.

April 2017

Evaluation of biomedical waste in Kogi State University Teaching Hospital, Anyigba, Kogi State, Nigeria

Adequate handling, efficient treatment and effective methods of biomedical waste play a vital role in the hospital infection control programme. Inadequate management of healthcare waste is a serious concern in many developing countries due to the risks posed to human health and environment. This study evaluates the biomedical waste generated at the Kogi State University Teaching Hospital, Anyigba. Seven wards were...

Author(s): Sawyerr H. O., Adeolu A. T., Salami O. O., and Adejoh P. A.

March 2017

Heavy metal contamination in Thelesperma megapotamicum

This study describes heavy metal (HM) contamination in the most commonly used herbal tea in several American Indian (AI) communities in northwestern New Mexico. The Navajo (Diné) reservation is located in an area that was heavily impacted by contamination associated with Uranium (U) mining that occurred from 1945 to 1988 and where more than 1,100 unreclaimed abandoned U mines and structures remain. The study...

Author(s): Christine Samuel-Nakamura, Felicia S. Hodge, Jane L. Valentine, and Wendie A. Robbins

March 2017

Herbal teas heavy metal evaluation with renal function assessment in regular consumers in Benin

Herbal teas are openly sold in markets and main streets of big cities like Cotonou in Benin. Most people treat themselves at low cost with wide variety of herbal plants with proven therapeutic properties. The purpose of this research was to evaluate the content of heavy metals in herbal teas sold daily in Cotonou. In addition, we would evaluate if this heavy metal content of herbal teas could affect the renal function...

Author(s): Allabi A. C., Adounkpe F., Vigan J., Gbegbe M., Topanou A., and Fayomi B.

February 2017

Modification of biochemical and haematological parameters during 90-days subchronic toxicity assessment of Carissa edulis in Wistar rats

A 90-days subchronic toxicity assay was evaluated on the aqueous extract of Carissa edulis leaves. Wistar rats were fed daily with oral doses of 125, 31.25 and 7.87 mg/kg of C. edulis leaves extracts. Toxic effects were assessed using physiological observation, body weight, relative organ weights, feed consumption, biochemical, haematological and histopathological parameters. Many changes of biological values were...

Author(s): Osseni Razack , Adanle Etienne, Adjagba Marius,  Bonaventure Awede,  Hountohotègbè Tatiana,  Bigot andré, Raphaël Darboux and Anatole Lalèyè

January 2017

Ameliorative effects of melatonin on brain biochemical changes induced by subchronic co-administration of chlorpyrifos and cypermethrin in male Wistar rats

The present study was aimed at evaluating the ameliorative effects of melatonin on chlorpyrifos and cypermethrin induced brain biochemical changes involving malonadialdehyde (MDA), catalase, superoxide dismutase, glutathione peroxidise and acetyl cholinesterase in male Wistar rats. The fifty adult male Wistar rats used for this study were divided into 5 groups of 10 animals each. Group I was administered distilled...

Author(s): S. B. Idris, S. F. Ambali and M. M. Suleiman

December 2016

Spirulina protects against tacrolimus-induced hepatic and renal toxicity in rats: A biochemical and histological study

Tacrolimus is a powerful immunosuppressive agent with hepatotoxic and nephrotoxic effects. It has a protective role against many toxicants. This study was conducted to evaluate the possible protective role of spirulina against tacrolimus induced hepatotoxicity and nephrotoxicity. Forty adult male albino rats divided into 4 groups. Group I, control group, Group II, spirulina group (received spirulina 500 mg/Kg body...

Author(s): Zakaria A. Elzawahry, Marwa A. Abass, Manal R. Abd El-Haleem, Reda A. Abdel Hamid and Hebatallah H. Atteia

December 2016

Hypothetical adjustment of the acceptable daily intake and correction of the underrated risk: A case study of glyphosate-based herbicides

Following the introduction of genetically-engineered glyphosate-resistant (GEGR) crops, commercially known as Roundup Ready (RR), no pesticide’s active principle has been used as much as glyphosate; yet its safety measures have been sternly disputed.  After its classification by the International Agency for Research on Cancer (IARC) as probably carcinogenic to humans in 2015, scientists, activists, regulators...

Author(s): Yehia A. Ibrahim

December 2016

Fast food premium toys as a significant source of lead and chromium to the environment

Electronic fast food premiums were investigated for their ability to leach toxic metals into the environment. Low levels of the metals barium, cadmium, chromium, and mercury were detected. Significant quantities of lead were found, up to 177 mg/L, over thirty five times the permissible levels. Key words: Waste, management, toxic, metal, leachate, lead, toys.

Author(s): Short D. B., Badger P., Lorenzi A., Mentzer B., Bearer H., Graves P. S., Harris J. V., Mahoney K. E., Schwaderer A. M., Shennan C. M., Siters A. and Warner C.

November 2016

Assessment of Ochratoxin A intake due to consumption of coffee and cocoa derivatives marketed in Abidjan (Côte d’Ivoire)

Ochratoxin A is a mycotoxin produced by moulds belonging to the Aspergillus and Penicillium species, and is a common contaminant of various food products. Ochratoxin A is known for its nephrotoxic and carcinogenic effects; protective actions to protect consumer health must be established. The aim of this study was to assess the level of contamination of manufactured coffee and cocoa-based products marketed in Abidjan to...

Author(s): Pierre Manda, Aholia Jean Baptiste Adepo, Jean Verdier Ngbé and Djédjé Sébastien Dano

October 2016

Accumulation and distribution of organochlorine and organophosphorus pesticide residues in water, sediments and fishes, Heteropneustis fossilis and Puntius ticto from Kali River, India

The present study focused on distribution pattern of persistent organochlorine and organophosphorus pesticides residues found in water, sediments and fish tissues from the Kali River. The total 10 pesticides were observed viz., monochrotophos, parathione, phorete, malathion, α- BHC, β- BHC, γ-BHC, δ-BHC, endrine and endosulfon using gas chromatography electron capture detector technique. The...

Author(s): P. K. Maurya and D. S. Malik

September 2016

Assessment of heavy metals and estimation of human health risk in Tilapia fish from Naik Lake of Nagpur, India

Gills and muscles of Tilapia fish from Naik lake of Nagpur city were estimated for heavy metals (Zinc, Lead, Nickel, Copper and Cadmium) using inductively coupled plasma optical emission spectrometry (ICP-OES). Results showed higher concentrations of heavy metals in gills than in muscles of tilapia fish. Trends of heavy metal concentrations in gills and muscles of tilapia fish were found Zn > Pb> Ni> Cu...

Author(s): Manisha D. Giripunje, Abhay B. Fulke, and Pravin U. Meshram

August 2016

Analysis of potential mutagenic effects of World Trade Center dust on in vitro systems

Thousands of tons of particulate matter were inhaled and ingested by rescue workers and the residents of New York City (NYC) after the attack on the World Trade Center (WTC) on September 11, 2001. This study examined the chemical and physical effects of dust from WTC, in addition to possible mutagenic evidence with in vitro methods and hopes to add credibility to the link between World Trade Center dust inhalation and...

Author(s): Barbara Soares, Patricia Rivera, Felix Dailey and Ann Marie DiLorenzo

July 2016

Combined arsenic and di-(2-ethylhexyl) phthalate exposure elicits responses in brain ATPases different from hepatic and renal activities in rats

Arsenic and di-(2-ethylhexyl) phthalate (DEHP) are environmentally ubiquitous and epidemiologically important toxic agents that millions of people are currently exposed to, worldwide. Although the adverse impact due to exposure to either arsenic or DEHP are documented, the toxicological effects of co-exposure to these agents are largely unknown. In this study, exposure to these chemicals was investigated for their...

Author(s): Olusegun K. Afolabi, Regina N. Ugbaja and Oladipo Ademuyiwa

May 2016

Heavy metal contamination of food in a developing country like Bangladesh: An emerging threat to food safety

This review paper highlighted possible ways of heavy metal contamination of food chain in a developing country like Bangladesh as it is considered an emerging threat for food safety. The review paper was prepared over a period of six months by searching and collecting data of various studies done in Bangladesh from original articles of many national and international journals. Also, data were taken from related review...

Author(s): Hezbullah, M., Sultana, S. , Chakraborty, S. R. and Patwary, M. I.

August 2015

Determination of some selected heavy metals in spinach and irrigated water from Samaru Area within Gusau Metropolis in Zamfara State, Nigeria

Due to insufficient clean water resources, wastewater is largely used for irrigation of vegetables and fruits in many developing countries like Nigeria. As a result of this, vegetables in spite of providing nutrients also accumulate toxic metals and causes health risks. In the present study, the levels of heavy metals (lead (Pb), cadnium (Cd), iron (Fe), zinc (Zn), and copper (Cu)), were analyzed using Atomic Absorption...

Author(s): Salawu K., Barau M. M., Mohammed D., Mikailu D. A., Abdullahi B. H. and Uroko R. I.

July 2015

Teratogenic and embryotoxic effects of orally administered cypermethrin in pregnant albino rats

Lack of consensus in published works regarding cypermethrin's ability to produce teratogenic and embyotoxic effects has led to postulations. The aim of this study was to evaluate the teratogenic and embryotoxic effects of cypermethrin in 5% vegetable oil using albino rats. Acute toxicity study of cypermethrin was evaluated using Probit analysis method. Percentage mortality was calculated and LD50 was...

Author(s): Emeka Promise Madu

July 2015

Evaluation of five medicinal plants at gas flaring site, using foliar photomicrography

Gas flaring is a recognized polluting agent in the environment, affecting all forms of life. The gases and particulate matters (dust, mist and fog) follow the same diffusive pathway with carbon IV oxide into the plant leaf, where they react with enzymes, hormones, and other biochemical molecules, resulting in the deformation of organelles with adverse consequences. In this study, foliar photomicrography analysis of five...

Author(s): Otuu F. Chibuisi, Nwadinigwe Alfreda and Okwuosa, C.N.

June 2015

Prevalence and determinants of pesticide use in informal households in Mulago II parish, Kampala Uganda

The indiscriminate use of pesticides in developing countries has impacted negatively on the environment and public health. Despite that informal households in Uganda carry a high pest burden, the safe use and disposal of pesticides is poorly studied. We determined the prevalence and pesticide use practices among the informal households in Mulago, a suburb of Kampala city. A cross-sectional survey was conducted among...

Author(s): Kibuule Dan and Kagoya Harriet Rachel

May 2015

Gross and histopathological studies of Diclofenac, Ibuprofen and Nimesulide induced toxicity in broilers

The present experimental work was conducted to elucidate the gross and histopathological studies in broiler chicks when treated with Diclofenac sodium, Ibuprofen and Nimesulide. For this study, 120 apparently healthy broiler chicks of either sexes were randomly divided into 10 groups comprising of 10 birds in 9 groups and 30 birds in control group. The broilers of Diclofenac groups were given 10, 20 and 30 mg/kg body...

Author(s): Majid Shafi, Omer Khalil Baba and Umesh Kumar Garg  

May 2015

Influence of starch addition on properties of methylolated urea/starch copolymer blends for application as a binder in the coating industry

Urea formaldehyde resin was reactively blended with various concentrations (10 to 70%) of Cassava starch in order to formulate a paint binder for emulsion paint formulation. Some physical properties and formaldehyde emission of the blended resin were investigated. Viscosity initially decreased before a gradual increase was noted with increase in starch concentration. Refractive index and elongation at break increased...

Author(s): S. A. Osemeahon, O. N. Maitera, A. J. Hotton and B. J. Dimas  

April 2015

Sub-lethal effect of cypermethrin on acetylcholinesterase (AChE) activity and acetylcholine (Ach) content in selected tissues of Channa striatus (Bloch.)

This study was carried out to investigate the sub-lethal effect of cypermethrin on acetylcholinesterase (AChE) activity and acetylcholine (ACh) content in various organ tissues of Channa striatus. Activity of AChE and ACh content was estimated in the tissues of brain, gills, liver, kidney, intestine and muscle of the exposed fish at regular intervals of 1, 7, 15 and 30 days. The study revealed that the inhibition of the...

Author(s): Osman Ahmed, S. A. Mastan, S. Rabia Banu and P. Indira

March 2015

Evaluation of the fungitoxic and fungistatic potential of the root extractsof male papaya plant and female papaya plant (Carica papaya L.)

The fungicidal and fungistatic potential of methanolic root extract of male Carica papaya against Phomopsis vexans which affects egg plants (Solanum melongena L.) leading to the condition called the “Phomopsis blight” was investigated. Result of the experiments revealed that the aqueous extract did not show significant activity, but comparatively the methanol extract of male root demonstrated significant...

Author(s): Gowthami Yaram, Chandrasehar Govindan, Deepa Venkataramulu, Darsana Rajaputhran,Chitrikha Thirunavukkarasu and Goparaju Anumolu  

February 2015

Exposure to ZnO-NPs enhanced gut- associated microbial activity in Eisenia fetida

With advent of the nanotechnology era, the environmental risk has continuously been receiving engineered nanomaterials, as well as their derivatives. Our current understanding of the potential impact of nanomaterials and their effect on soil organism is limited. The present study fills the gap between effect of manufactured nanomaterials (NPs) and their available natural scavengers. In the study,  earthworm Eisenia...

Author(s): Shruti Gupta, Tanuja Kushwah and Shweta Yadav

February 2015

Haemato-pathological effect of dichlorvos on blood picture and liver cells of albino rats

The effect of intraperitonal exposure of dichlorvos an organophosphate (OP) pesticide, on haematology parameters and liver pathology of Wister rats was investigated.  Thirty male albino rats grouped into six (6) of five rats each were injected with 0, 3.7, 7.4, 11.1, 14.8 and 18.5mg/kg of dichlorvos (DDVP) (1 ml/kg) respectively. The haematological parameters measured were red blood cells, haemoglobin; packed cell...

Author(s): Brown Holy, Kenanagha, B   and Onwuli, D.O

January 2015

Phorate poisoning of a leopard (Panthera pardus) in the Nilgiris

India is an agricultural country; animal husbandry has always been associated with agriculture. People still thrive upon animal products such as milk, meat and manure intensely for their essentialities. India has a huge cattle population and most of them graze in areas close to forests and their fringes competing for their pastoral needs with other wild animals. This then leads to human-wildlife conflicts, which tends...

Author(s): Boon Allwin and Stalin Vedamanickam

January 2015

Evidence of micronuclei in fish blood as a biomarker of genotoxicity due to surface run off agricultural fungicide (Propiconazole)

Micronuclei, nucleoplasmic bridges and nuclear buds are biomarkers of genotoxic events and chromosomal instability. In laboratory, these genome damages can be measured easily. The measurement of cytogenetic alterations in-vivo has considered an initial step in the risk assessment procedures by genotoxic agents. In fishes, micronucleus assay has shown useful in vivo techniques for genotoxicity testing, and potential for...

Author(s): Pallavi Srivastava and Ajay Singh

December 2014

Ameliorative effect of seed extract of Pterocarpus santalinus on coragen induced haematological alterations and serum biochemical changes in Charles Foster rats

In the present study, the ameliorative effect of an aqueous extract of Pterocarpus santalinus against coragen induced haematological changes, biochemical alterations and oxidative damage in Charles foster rats was undertaken. Coragen administration (1000 mg kg-1 body weight orally for 6 weeks) was associated with significant rise in serum levels of alkaline phosphatase, urea, uric acid and creatinine and enhanced lipid...

Author(s): Khushboo Dutta, Mohammad Ali, Azim Najam, Ranjit Kumar and Arun Kumar  

December 2014

Naturally contaminated feed with low levels of fumonisins with anti-mycotoxin additive and its impact in the immune cells and blood variables in broiler chickens

Ninety six one-day-old broiler chickens were used to evaluate the effect of feeding naturally contaminated rations with low levels of fumonisins (FBs) and the protective effect of a commercial anti-mycotoxin additive (AMA) on circulating and intestinal immune cells, blood biochemistry, hematological variables and biomarkers of FBs exposure. Birds were assigned in three groups: Negative control (NC), positive control...

Author(s): Pedro Celso Machado Júnior, Breno Castello Branco Beirão, Tobias Fernandes Filho, Max Ingberman, Celso Fávaro Júnior, and Luiz Felipe Caron,  

November 2014

Occurrence of some pesticides in Bhoj wetland Bhopal and their effect on phytoplankton community: An ecological perspective

The present communication deal with the analysis of water samples from Bhoj wetland to detect three pesticides (chlorpyrifos, monocrotophos and endosulfan) and to assess their individual toxicity to the phytoplankton community. Higher concentration of most of the pesticides was found to be in the pre-monsoon (March to May) 0.9 µg/l (monocrotophos) and post-monsoon (September to December) 1 µg/l...

Author(s): Ayaz A. Naik and Wanganeo A.

November 2014

The use of planktons as tools for monitoring water quality in oil polluted streams of the Niger Delta, Nigeria

The Niger Delta ecosystems of Nigeria, typically consisting of mangrove swamps and riparian forests, have come under threat in the last six decades as a result of environmental pollution from oil exploration, drilling, refining and transportation. This study examines two Niger Delta streams (Ogba Evie and Otor) to ascertain the extent of hydrocarbon and heavy metal pollution and the status of the biotic communities in...

Author(s): Amaeze Nnamdi Henry and Onyema Ikenna Charles  

October 2014

Determination of the effects of some artificial sweeteners on human peripheral lymphocytes using the comet assay

In this study, the genotoxicity of the artificial sweeteners acesulfame potassium, aspartame, saccharin, and sorbitol, which are used in food industry and by patients with diabetes, was investigated in human peripheral lymphocyte cells using the single-cell gel electrophoresis (comet) technique. Human lymphocyte cells were treated with the substances for three hour at each of the three dosages (1.25, 2.5, and 5 ppm)....

Author(s): Zeynep Fındıklı and Şifa Türkoğlu

October 2014

Bioaccumulation of heavy metals in cane rat (Thryonomys swinderianus) in Ogun State, Nigeria

Wild animals have provided complimentary protein for human populations across the world over the centuries. This study investigated on bioaccumulation of heavy metals in different organs of cane rat (Thryonomys swinderianus) and the health implications of its consumption. Four carcasses were collected from each of the four ecotomes (Mosinmi, Agbara, Omo forest reserve and Ibese) and concentrations of 7 heavy metals (Fe,...

Author(s): Durojaye A. Soewu, Olufemi M. Agbolade, Rasheed Y. Oladunjoye and Ibukun A. Ayodele

October 2014

Effect of dipentyl phthalate in 3-dimensional in vitro testis co-culture is attenuated by cyclooxygenase-2 inhibition

Exposure to phthalate esters is associated with changes in steroidogenesis, leading to the hypothesis that this is a primary mechanism of phthalate reproductive toxicity. However, some phthalate-induced male reproductive toxicity has been demonstrated in the absence of changes to testosterone production, suggesting additional mechanisms of action. There is evidence that phthalate exposure increases expression of the...

Author(s): Susanna Wegner, Xiaozhong Yu, Hee Yeon Kim, Sean Harris, William C. Griffith, Sungwoo Hong and Elaine M. Faustman

September 2014

Mitigating potential and antioxidant properties of aqueous seed extract of Leea guineensis against dichlorovos-induced toxicity in Wistar rats

  This work was carried out to access the mitigating potential of Leea guineensis aqueous seed extract against dichlorovos (DDVP)-induced toxicity in Wistar rats for ten days. Twenty Wistar albino rats (weighing 90 to 106 g) were divided into four groups (Normal, DDVP-induced untreated, DDVP-induced treated with 200 mg/kg of L. guineensis seed and DDVP-induced treated with 400 mg/kg L. guineensis seed by oral...

Author(s):   Ajiboye B.O., Salawu S.O., Okezie B., Oyinloye B.E., Ojo A.O., Onikanni S.A., Oso A.O., Asoso O.S. and Obafemi T.O.

September 2014

Identification and quantification of heavy metals in local drinks in Northern Zone of Nigeria

  Nine heavy metals were studied in locally prepared drinks, namely, “Zobo” and “Kunnu Zaki”. The samples were prepared from the outer covering (calyx) of the fruits of roselle Hibiscus sabdariffa and cereals (millet or guinea corn), respectively. Twenty samples of “Zobo” coded Zb1-Zb20 and twenty samples of “Kunnu Zaki” coded Kz1-Kz20 were bought from different...

Author(s):   Bakare-Odunola M. T. and Mustapha K. B.

August 2014

Response of liver and gills of Mystus gulioto the heavy metal pollutants and metacercarian infection

  Mystus gulio collected from the polluted waters of Veli lake in the Thiruvananthapuram district of Kerala, India was subjected to histopathological observations to study the effect of the pollutants on the tissue of the fishes. The epithelial layer of the secondary lamellae was lifted and detached from the underlying tissue, and was also seen in a degenerative form. The hepatocytes have lost their shape and...

Author(s):   Sherly Williams E., Beena V. S., Razeena Karim L. and Seethal Lal S.

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