Journal of
Toxicology and Environmental Health Sciences

  • Abbreviation: J. Toxicol. Environ. Health Sci.
  • Language: English
  • ISSN: 2006-9820
  • DOI: 10.5897/JTEHS
  • Start Year: 2009
  • Published Articles: 197

JTEHS Articles

October 2019

Safety assessment of Cymbopogon shoenanthus (L.) Spreng. (Poaceae) essential oils: Oral toxicity, dermal and eye irritancy investigations

The side effects prediction is a regulatory requirement prior the effective use of a new product as drug or pesticide constituent is allowed. The handling hazards of Cymbopogon schoenanthus essential oils (CSEO) were determined by investigating their acute and subacute toxicities as well as irritancy potential for eye and skin in compliance with the Organization for Economic Cooperation and Development guidelines. In...

Author(s): Sylvain Ilboudo, Geoffroy G. Ouédraogo, Ignace Sawadogo, Lazare Belemnaba, Sylvin Ouédraogo and Roger Ch. H. Nébié  

September 2019

Effect of lead on the activity of antioxidant enzymes and male reproductive hormones

Environmental exposure to heavy metals such as lead is detrimental to male reproductive system. Lead induced oxidative stress is believed to contribute immensely to male infertility. The study was designed to investigate the influence of environmental lead exposure on the activities of antioxidant enzymes and male reproductive hormones levels in male individuals of Bagega and Kawaye villages of Anka Local Government...

Author(s): S. Rabiu, M. G. Abubakar, D. M. Sahabi and M. A. Makusidi  

July 2019

Cellular energy budget in tropical freshwater fish following exposure to sublethal concentrations of cadmium

Under stressful conditions (toxicity), organisms often try to detoxify by mobilizing available energy sources with costs to various metabolic functions, such as growth or reproduction. Cellular energy allocation (CEA) is a methodology used to evaluate the energetic status and which relates with organisms’ overall condition and response to toxic stress. It consists of the integration of the energy reserves...

Author(s): Ezeonyejiaku Chigozie Damian, Ifedigbo Ikem Innocent , Okoye Charles Obinwanne and Ezenwelu Chijioke Obinna  

June 2019

Therapeutic assessment of Idebenone versus Titanium dioxide nanoparticles induced pulmonary injury in adult albino Rats: Experimental study

Titanium dioxide nanoparticles are extensively used metal in cosmetics, sunscreens, food products, paints and drugs, producing oxidative stress and deoxyribonucleic acid damage. This study aimed to improve the overall (TiO2NP) use and decrease its related health hazards through the following objective among albino rates: To assess the TiO2NPs oral administration pulmonary induced toxic effect and to study the beneficial...

Author(s): Dalia M. Amin, Aisha A. Abohashem, Samar A. Amer, Amany I. Ahmed and Amr A. Moustafa  

May 2019

Spatial distribution and operations of petrol stations in the Kassena-Nankana district (Ghana) and associated health and safety hazards

This study was conducted in Paga to assess the spatial distribution and operations of petrol stations and the associated health and safety hazards. Coordinates of the stations and the distances between them and the nearest residences were elicited and analysed using a GPS and ArcGIS software. Distances between fuel stations’ boundaries and the middle of the N10 highway and the distances between filling...

Author(s): Nang Biyogue Douti, Samuel Kojo Abanyie, Steve Ampofo and Ebenezer Ebo Yahans Amuah  

April 2019

The possible protective effect of Zingiber officinale extract on cyclophosphamide-induced cardiotoxicity in adult male albino rats

Cyclophosphamide, a cytotoxic alkylating agent, is an extensively used antineoplastic agent. Cardio-toxicity is considered as one of the limiting side effects of its use, which is attributed to oxidative stress. Zingiber officinale is powerful antioxidants against free radicals and oxidative attacks. The aim of this study is to investigate the possible protective effects of Z. officinale against cyclophosphamide induced...

Author(s): Nashwa Mohamad M. Shalaby, Abeer Ramzy H. Mahmoud, Nagah El-Sayed M. Ali, Nahla E. Ibrahem and Noura Hussein Abdel H. Mekawy  

March 2019

Poisonings with heavy metals and neoplasms - possible correlations

As a side effect of industrialization, some diseases have developed only recently, becoming a challenge for the medical specialists both in research and medical treatment fields. Among these, the poisoning with heavy metals occupies a certain category that must retain attention, due to since the effects of this kind of poisoning are very serious effects if these injuries poisonings are not properly recognized and...

Author(s): Lucia Bubulac, Dan Octavian Marculescu and Victor Lorin Purcarea  

March 2019

Post-epidemic lead exposure to animals following a decontamination exercise in gold mining village of Bagega, Zamfara State, Nigeria

This study focused on the evaluation of environmental lead contamination due to artisanal gold mining at a Nigerian village of Bagega one year after a clean-up exercise was carried out. Water samples were collected from earthen dams, faucets and wells, while plant and soil samples from grazing fields, residential areas and sites within the vicinity of the gold mine. The collected samples were digested and analyzed for...

Author(s): Mohammed Bashir Tijjani, Bello Mohammed Agaie, Kenneth Idowu Onifade, Abdullahi Sulaiman Mainasara, Ibrahim Lamidi Yusuf and Abdulyakeen Olawale Tijjani  

February 2019

Acute toxicity evaluation of water extract stem barks of Balanites aegyptiaca on adults of three different fish species

A 96 h static toxicity bioassay was carried out to examine fish responses and to determine the median lethal concentration (LC50) of Balanites aegyptiaca stem bark extract on adults of Brycinus nurse, Labeobarbus bynni and Labeobarbus intermedius. Experimental fish were exposed to piscicide plant extract of 0.0 (control), 15.0, 17.5, 20.0, 22.5, and 25.0 mgL-1. Fish exposed to these extracts except the control showed...

Author(s): Alamrew Eyayu, and Abebe Getahun  

February 2019

Ameliorative role of quercetin in iron overload induced heart and brain toxicity in adult male albino rats

Although iron is an essential element for life, its excess is linked to many disorders. The aim of this study is to investigate the effect of quercetin on iron induced toxicity on the heart and brain in adult male albino rats. 50 adult male albino rats were equally divided into groups; Group I (negative control), Group II (positive control) received normal saline 0.9%. Group III (Quercetin group) was treated with...

Author(s): El-Sayed Eman H. K., Zeinab Abdou Mohammed and Mona Mostafa Ahmed

January 2019

Determination of polycyclic aromatic hydrocarbons in blood plasma of neurology patients

The etiology of many neurological cases cannot be easily delineated, making the investigation, and treatment to be challenging. This study aims to screen the blood of neurology patients presenting for the first time in the hospital for Polycyclic Aromatic Hydrocarbons (PAHs) using Flame Ionization Detector – Gas Chromatography. Fourteen PAHs were detected in the samples. The results showed that flourene and...

Author(s): Olabanji Iyabo Oluremi, Asubiojo Olabode Idowu, Komolafe Morenikeji Adedoyin, Akintomide Anthony and Adeniji Ayodeji Oluwole  

December 2018

Potential human risk of dissolved heavy metals in gold mine waters of Gauteng Province, South Africa

This paper evaluates the potential health risks from dissolved heavy metals in water sources around a gold mining area in the Gauteng Province of South Africa. In this study, 29 samples of water were collected around a gold mining area and were analyzed for Arsenic (As), Lead (Pb), Mercury (Hg), Cadmium (Cd), Chromium (Cr), Copper (Cu), Zinc (Zn), Cobalt (Co) and Nickel (Ni) using Inductively Coupled Plasma-Mass...

Author(s): C. Kamunda, M. Mathuthu and M. Madhuku  

November 2018

Human kidney injury molecule-1 and interleukin-18 as predictive markers of nephrotoxicity in acute organophosphorus poisoned patients in Zagazig University hospitals

Organophosphorus (OP) poisoning is a major common cause of mortality and morbidity in most countries. Some clinical cases developed renal injury after acute OP poisoning. The aim of our study is to evaluate the levels of kidney injury molecule-1(KIM-1) and interleukin -18(IL-18) in acute OP poisoned patients as early predictors of OP induced nephrotoxicity. Over a period of one year, the observational cross sectional...

Author(s): Arwa A. El-Sheikh, Eman El-Sayed Khayal and Reem Allam  

November 2018

Influence of dry erase ink solvent mixtures on eye irritation

Teaching is the process of imparting knowledge by teachers in learners. To enhance this, methods of presenting information visually to a full room of students at once are used. This includes writing on whiteboards written using whiteboard marker pens. Dry erase ink for whiteboard marker pen is composed of volatile solvent vehicle which easily vaporizes allowing the mark to dry on the surface of the whiteboard. Different...

Author(s): Sabina Muthoni Muchemi, Wilkister Nyaora Moturi, George Morara Ogendi  

July 2018

The amelorative effect of L-arginin and omega-3 fatty acid against sodium valproate induced hepatotoxicity

Sodium valproate (VPA) used in epilepsy and has hepatotoxic effect in mammals. This work is to assess the role of L-arginin and omega-3 fatty acid against VPA oxidative stress on liver. This study was carried out on 70 rats divided into 7 groups each of 10 rats treated orally once daily 6days/ week; Group I (control), Group II ( L-arginin): each rat was received 300 mg/kg L-arginin, Group III (omega-3): each rat...

Author(s): Dalia M. Amin, Marwa T. Abaza, Walaa M. Sarhaan, Amany I. Ahmed, Amr A. Moustafa  

June 2018

Biochemical analysis and toxicity studies of some heavy metals and their correlation with different diseases

The problem of heavy metal toxicity is a burning issue all over the world and more prominent in countries like Pakistan, India and Bangladesh. Often times, it is seen that the people of the affected areas are unaware of the toxic effects of these metals. Medical practitioners at the same time did not investigate the presence of heavy metals in the body. The present study aims to analyze the concentration of toxic heavy...

Author(s): Muhammad Jahangir, Hafiz Muhammad Faizan Haider, Zafar Niaz, Sajid Abaidullal and Dawood Ilyas Minhas

May 2018

Organochlorine pesticides contamination in human milk in Abidan (Côte d’Ivoire)

Organochlorine pesticides belong to the class of persistent organic pollutants (POPs). They are deeply involved in environmental issues and represent a real threat for human health. The aim of this study was to assess the level of organochlorine pesticides contamination in human milk through two studies of POPs biomonitoring performed in 2010 and 2015 in Côte d'Ivoire. Primiparous breastfeeding mothers...

Author(s): Manda Pierre,  Adepo Aholia Jean-Baptiste and Dano Djédjé Sébastien

April 2018

Novel expression of the biomarker, Nε-hexanoyl lysine in gibberellic acid induced bone toxicity in adult albino rats

Plants hormones are widely used in agriculture to alter plant characteristics as growth regulators. Gibberellic acid (GA3) plays important role in promoting plant growth, and cell differentiation. This work was performed to investigate the relationship between lipooxidative damage marker (HEL) and bone damage induced by GA3 in adult albino rats. This study was carried out on 20 adult albino rats for 4 weeks treated 6...

Author(s): Dalia M. Amin, Aisha A. Abohashem, Ola A. Harb, Walaa M. Sarhan and Marwa A. Shabana

December 2017

Effects of contaminated natural soil by Glyphosan SL on biochemical responses of the earthworm Eisenia sp.

Biochemical biomarkers are widely used for the monitoring environmental quality since they can act as early warning signals, for potential ecosystem degradation caused by contaminants. In order to investigate the acute and chronic effects of a commercial formulation of glyphosate on antioxidant defenses (glutathione peroxidase, GPx; glutathione-S-transferase, GST; and reduced glutathione, GSH) and oxidative damage...

Author(s): Leida Marcano, Juanny Hernández, Edgar Zapata-Vívenes and Analía León

November 2017

Hematotoxicity status of lead and three other heavy metals in cow slaughtered for human consumption in Jos, Nigeria

Heavy metals are of public health concern worldwide due to their damaging effects on human and animal health, the environment and life in general. This study assessed concentration levels of some toxic heavy metals: Cadmium (Cd), lead (Pb), copper (Cu) and magnesium (Mg) in blood samples of ten (10) cattle slaughtered in two areas (Jos North and South) of Plateau State, Northern Nigeria. The results were compared with...

Author(s): Lucky Legbosi Nwidu and Temitayo Lucia Ohemu

October 2017

Lactate and creatine phosphokinase as potential independent predictors of organophosphrus poisoning severity in Zagazig University Hospital Patients, Egypt

This study aimed to assess the correlation of serum lactate and creatine phosphokinase (CPK) levels, and their association with severity of organophosphrus poisoning in order to use one of them or both as tools in predicting prognosis. This study was conducted over one year and 68 organophosphate (OP)-poisoned patients were enrolled. Clinical severity of cases was categorized according to Peradeniya organophosphorus...

Author(s): Manar H. Arafa, Nashwa M. Shalaby and Hebatallah H. Atteia

July 2017

Investigation of possible human exposure to metals concentration in vegetables

This study assesses the health risk of metals concentration in spinach and onions obtained from different suppliers (suppliers 1, 2, 3, 4 and 5) in Mafikeng, South Africa. The following elemental concentrations of As, Ba, Bi, Cu, Cr, Co, I, Mn, Ni, Pb, Sr, Th, Rb, V and U were tested in spinach and onions using inductively coupled plasma–mass spectrometry (ICP-MS). The result shows that Bi, I, Th, Pb and U were...

Author(s): Hilma Rantilla Amwele, Lebogang Motsei, Gideon Kalumbu, Nnenesi Kgabi, Raymond Limen Njinga, and Victor Makondelele Tshivhase

June 2017

Analysis of the incidence of the deficit of sanitation on the health of the populations in a context of urban growth: Case of the municipalities Yopougon, Abobo and Treichville' (Abidjan, Ivory Coast)

The emergence of pathologies and their impacts on the health of the populations were studied in the municipalities of Yopougon, Abobo, and Treichville. This study highlights the conditions of noxious life and the health of the populations. To achieve this, a transverse investigation with the households was conducted on 300 households in 2013. It is concerned with the sources of water supply. It was noticed that 80% of...

Author(s): Yapo Toussaint Wolfgang, , Amin N’cho Christophe, Yapo Ossey Bernard, and Mambo Veronique

June 2017

Maternal and foetal toxicity induced by exposure to mixture of dimethoate and cypermethrin in albino rats

The use of pesticide mixture to combat increased resistance by pest, to single chemical insecticide has brought about an increase in the use of pesticide mixture from different class, with its attendant toxicity. The objective of this study was to evaluate the maternal and foetal toxicity associated with dimethoate and cypermethrin, the two insecticides that are normally mixed to reduce pest resistance. 100...

Author(s): S. B. Ramon-Yusuf, Y. O. Aliu, O. A. Salawu, I. Chahoud and S. F. Ambali

May 2017

Biosorption of heavy metals onto different eco-friendly substrates

Fungi play an important role in biosorption of heavy metals in heavily contaminated soil. Five metals-tolerant fungal species were isolated from two different contaminated soil (soils 1 and 2). The number of fungal colonies isolated from the contaminated soil 2 was higher than that of soil 1. The most resistant fungal species for the toxic studied metals (Pb, Cd, Cu and Zn) was Rhizopus stolonifier followed by...

Author(s): Eman M. Fawzy, Fatma F. Abdel-Motaal and Soad A. El-zayat

May 2017

Evaluation of occupational exposure to metal dust on the liver of road construction workers in Abuja metropolis

Increasing air pollution levels due to rapid urbanization and growth in infrastructural facilities coupled with low level of standard safety procedures have been observed in Nigeria, and become a major source of concern. The study evaluated the effects of occupational exposure to metal dust on the liver of road construction workers in Abuja metropolis. Blood samples were used in the measurement of Lead, cadmium,...

Author(s): Ojevwe, D. D. and Osadolor, H. B.

April 2017

Evaluation of biomedical waste in Kogi State University Teaching Hospital, Anyigba, Kogi State, Nigeria

Adequate handling, efficient treatment and effective methods of biomedical waste play a vital role in the hospital infection control programme. Inadequate management of healthcare waste is a serious concern in many developing countries due to the risks posed to human health and environment. This study evaluates the biomedical waste generated at the Kogi State University Teaching Hospital, Anyigba. Seven wards were...

Author(s): Sawyerr H. O., Adeolu A. T., Salami O. O., and Adejoh P. A.

March 2017

Heavy metal contamination in Thelesperma megapotamicum

This study describes heavy metal (HM) contamination in the most commonly used herbal tea in several American Indian (AI) communities in northwestern New Mexico. The Navajo (Diné) reservation is located in an area that was heavily impacted by contamination associated with Uranium (U) mining that occurred from 1945 to 1988 and where more than 1,100 unreclaimed abandoned U mines and structures remain. The study...

Author(s): Christine Samuel-Nakamura, Felicia S. Hodge, Jane L. Valentine, and Wendie A. Robbins

March 2017

Herbal teas heavy metal evaluation with renal function assessment in regular consumers in Benin

Herbal teas are openly sold in markets and main streets of big cities like Cotonou in Benin. Most people treat themselves at low cost with wide variety of herbal plants with proven therapeutic properties. The purpose of this research was to evaluate the content of heavy metals in herbal teas sold daily in Cotonou. In addition, we would evaluate if this heavy metal content of herbal teas could affect the renal function...

Author(s): Allabi A. C., Adounkpe F., Vigan J., Gbegbe M., Topanou A., and Fayomi B.

February 2017

Modification of biochemical and haematological parameters during 90-days subchronic toxicity assessment of Carissa edulis in Wistar rats

A 90-days subchronic toxicity assay was evaluated on the aqueous extract of Carissa edulis leaves. Wistar rats were fed daily with oral doses of 125, 31.25 and 7.87 mg/kg of C. edulis leaves extracts. Toxic effects were assessed using physiological observation, body weight, relative organ weights, feed consumption, biochemical, haematological and histopathological parameters. Many changes of biological values were...

Author(s): Osseni Razack , Adanle Etienne, Adjagba Marius,  Bonaventure Awede,  Hountohotègbè Tatiana,  Bigot andré, Raphaël Darboux and Anatole Lalèyè

January 2017

Ameliorative effects of melatonin on brain biochemical changes induced by subchronic co-administration of chlorpyrifos and cypermethrin in male Wistar rats

The present study was aimed at evaluating the ameliorative effects of melatonin on chlorpyrifos and cypermethrin induced brain biochemical changes involving malonadialdehyde (MDA), catalase, superoxide dismutase, glutathione peroxidise and acetyl cholinesterase in male Wistar rats. The fifty adult male Wistar rats used for this study were divided into 5 groups of 10 animals each. Group I was administered distilled...

Author(s): S. B. Idris, S. F. Ambali and M. M. Suleiman

December 2016

Spirulina protects against tacrolimus-induced hepatic and renal toxicity in rats: A biochemical and histological study

Tacrolimus is a powerful immunosuppressive agent with hepatotoxic and nephrotoxic effects. It has a protective role against many toxicants. This study was conducted to evaluate the possible protective role of spirulina against tacrolimus induced hepatotoxicity and nephrotoxicity. Forty adult male albino rats divided into 4 groups. Group I, control group, Group II, spirulina group (received spirulina 500 mg/Kg body...

Author(s): Zakaria A. Elzawahry, Marwa A. Abass, Manal R. Abd El-Haleem, Reda A. Abdel Hamid and Hebatallah H. Atteia

December 2016

Hypothetical adjustment of the acceptable daily intake and correction of the underrated risk: A case study of glyphosate-based herbicides

Following the introduction of genetically-engineered glyphosate-resistant (GEGR) crops, commercially known as Roundup Ready (RR), no pesticide’s active principle has been used as much as glyphosate; yet its safety measures have been sternly disputed.  After its classification by the International Agency for Research on Cancer (IARC) as probably carcinogenic to humans in 2015, scientists, activists, regulators...

Author(s): Yehia A. Ibrahim

December 2016

Fast food premium toys as a significant source of lead and chromium to the environment

Electronic fast food premiums were investigated for their ability to leach toxic metals into the environment. Low levels of the metals barium, cadmium, chromium, and mercury were detected. Significant quantities of lead were found, up to 177 mg/L, over thirty five times the permissible levels. Key words: Waste, management, toxic, metal, leachate, lead, toys.

Author(s): Short D. B., Badger P., Lorenzi A., Mentzer B., Bearer H., Graves P. S., Harris J. V., Mahoney K. E., Schwaderer A. M., Shennan C. M., Siters A. and Warner C.

November 2016

Assessment of Ochratoxin A intake due to consumption of coffee and cocoa derivatives marketed in Abidjan (Côte d’Ivoire)

Ochratoxin A is a mycotoxin produced by moulds belonging to the Aspergillus and Penicillium species, and is a common contaminant of various food products. Ochratoxin A is known for its nephrotoxic and carcinogenic effects; protective actions to protect consumer health must be established. The aim of this study was to assess the level of contamination of manufactured coffee and cocoa-based products marketed in Abidjan to...

Author(s): Pierre Manda, Aholia Jean Baptiste Adepo, Jean Verdier Ngbé and Djédjé Sébastien Dano

October 2016

Accumulation and distribution of organochlorine and organophosphorus pesticide residues in water, sediments and fishes, Heteropneustis fossilis and Puntius ticto from Kali River, India

The present study focused on distribution pattern of persistent organochlorine and organophosphorus pesticides residues found in water, sediments and fish tissues from the Kali River. The total 10 pesticides were observed viz., monochrotophos, parathione, phorete, malathion, α- BHC, β- BHC, γ-BHC, δ-BHC, endrine and endosulfon using gas chromatography electron capture detector technique. The...

Author(s): P. K. Maurya and D. S. Malik

September 2016

Assessment of heavy metals and estimation of human health risk in Tilapia fish from Naik Lake of Nagpur, India

Gills and muscles of Tilapia fish from Naik lake of Nagpur city were estimated for heavy metals (Zinc, Lead, Nickel, Copper and Cadmium) using inductively coupled plasma optical emission spectrometry (ICP-OES). Results showed higher concentrations of heavy metals in gills than in muscles of tilapia fish. Trends of heavy metal concentrations in gills and muscles of tilapia fish were found Zn > Pb> Ni> Cu...

Author(s): Manisha D. Giripunje, Abhay B. Fulke, and Pravin U. Meshram

August 2016

Analysis of potential mutagenic effects of World Trade Center dust on in vitro systems

Thousands of tons of particulate matter were inhaled and ingested by rescue workers and the residents of New York City (NYC) after the attack on the World Trade Center (WTC) on September 11, 2001. This study examined the chemical and physical effects of dust from WTC, in addition to possible mutagenic evidence with in vitro methods and hopes to add credibility to the link between World Trade Center dust inhalation and...

Author(s): Barbara Soares, Patricia Rivera, Felix Dailey and Ann Marie DiLorenzo

July 2016

Combined arsenic and di-(2-ethylhexyl) phthalate exposure elicits responses in brain ATPases different from hepatic and renal activities in rats

Arsenic and di-(2-ethylhexyl) phthalate (DEHP) are environmentally ubiquitous and epidemiologically important toxic agents that millions of people are currently exposed to, worldwide. Although the adverse impact due to exposure to either arsenic or DEHP are documented, the toxicological effects of co-exposure to these agents are largely unknown. In this study, exposure to these chemicals was investigated for their...

Author(s): Olusegun K. Afolabi, Regina N. Ugbaja and Oladipo Ademuyiwa

May 2016

Heavy metal contamination of food in a developing country like Bangladesh: An emerging threat to food safety

This review paper highlighted possible ways of heavy metal contamination of food chain in a developing country like Bangladesh as it is considered an emerging threat for food safety. The review paper was prepared over a period of six months by searching and collecting data of various studies done in Bangladesh from original articles of many national and international journals. Also, data were taken from related review...

Author(s): Hezbullah, M., Sultana, S. , Chakraborty, S. R. and Patwary, M. I.

August 2015

Determination of some selected heavy metals in spinach and irrigated water from Samaru Area within Gusau Metropolis in Zamfara State, Nigeria

Due to insufficient clean water resources, wastewater is largely used for irrigation of vegetables and fruits in many developing countries like Nigeria. As a result of this, vegetables in spite of providing nutrients also accumulate toxic metals and causes health risks. In the present study, the levels of heavy metals (lead (Pb), cadnium (Cd), iron (Fe), zinc (Zn), and copper (Cu)), were analyzed using Atomic Absorption...

Author(s): Salawu K., Barau M. M., Mohammed D., Mikailu D. A., Abdullahi B. H. and Uroko R. I.

July 2015

Teratogenic and embryotoxic effects of orally administered cypermethrin in pregnant albino rats

Lack of consensus in published works regarding cypermethrin's ability to produce teratogenic and embyotoxic effects has led to postulations. The aim of this study was to evaluate the teratogenic and embryotoxic effects of cypermethrin in 5% vegetable oil using albino rats. Acute toxicity study of cypermethrin was evaluated using Probit analysis method. Percentage mortality was calculated and LD50 was...

Author(s): Emeka Promise Madu

July 2015

Evaluation of five medicinal plants at gas flaring site, using foliar photomicrography

Gas flaring is a recognized polluting agent in the environment, affecting all forms of life. The gases and particulate matters (dust, mist and fog) follow the same diffusive pathway with carbon IV oxide into the plant leaf, where they react with enzymes, hormones, and other biochemical molecules, resulting in the deformation of organelles with adverse consequences. In this study, foliar photomicrography analysis of five...

Author(s): Otuu F. Chibuisi, Nwadinigwe Alfreda and Okwuosa, C.N.

June 2015

Prevalence and determinants of pesticide use in informal households in Mulago II parish, Kampala Uganda

The indiscriminate use of pesticides in developing countries has impacted negatively on the environment and public health. Despite that informal households in Uganda carry a high pest burden, the safe use and disposal of pesticides is poorly studied. We determined the prevalence and pesticide use practices among the informal households in Mulago, a suburb of Kampala city. A cross-sectional survey was conducted among...

Author(s): Kibuule Dan and Kagoya Harriet Rachel

May 2015

Gross and histopathological studies of Diclofenac, Ibuprofen and Nimesulide induced toxicity in broilers

The present experimental work was conducted to elucidate the gross and histopathological studies in broiler chicks when treated with Diclofenac sodium, Ibuprofen and Nimesulide. For this study, 120 apparently healthy broiler chicks of either sexes were randomly divided into 10 groups comprising of 10 birds in 9 groups and 30 birds in control group. The broilers of Diclofenac groups were given 10, 20 and 30 mg/kg body...

Author(s): Majid Shafi, Omer Khalil Baba and Umesh Kumar Garg  

May 2015

Influence of starch addition on properties of methylolated urea/starch copolymer blends for application as a binder in the coating industry

Urea formaldehyde resin was reactively blended with various concentrations (10 to 70%) of Cassava starch in order to formulate a paint binder for emulsion paint formulation. Some physical properties and formaldehyde emission of the blended resin were investigated. Viscosity initially decreased before a gradual increase was noted with increase in starch concentration. Refractive index and elongation at break increased...

Author(s): S. A. Osemeahon, O. N. Maitera, A. J. Hotton and B. J. Dimas  

April 2015

Sub-lethal effect of cypermethrin on acetylcholinesterase (AChE) activity and acetylcholine (Ach) content in selected tissues of Channa striatus (Bloch.)

This study was carried out to investigate the sub-lethal effect of cypermethrin on acetylcholinesterase (AChE) activity and acetylcholine (ACh) content in various organ tissues of Channa striatus. Activity of AChE and ACh content was estimated in the tissues of brain, gills, liver, kidney, intestine and muscle of the exposed fish at regular intervals of 1, 7, 15 and 30 days. The study revealed that the inhibition of the...

Author(s): Osman Ahmed, S. A. Mastan, S. Rabia Banu and P. Indira

March 2015

Evaluation of the fungitoxic and fungistatic potential of the root extractsof male papaya plant and female papaya plant (Carica papaya L.)

The fungicidal and fungistatic potential of methanolic root extract of male Carica papaya against Phomopsis vexans which affects egg plants (Solanum melongena L.) leading to the condition called the “Phomopsis blight” was investigated. Result of the experiments revealed that the aqueous extract did not show significant activity, but comparatively the methanol extract of male root demonstrated significant...

Author(s): Gowthami Yaram, Chandrasehar Govindan, Deepa Venkataramulu, Darsana Rajaputhran,Chitrikha Thirunavukkarasu and Goparaju Anumolu  

February 2015

Exposure to ZnO-NPs enhanced gut- associated microbial activity in Eisenia fetida

With advent of the nanotechnology era, the environmental risk has continuously been receiving engineered nanomaterials, as well as their derivatives. Our current understanding of the potential impact of nanomaterials and their effect on soil organism is limited. The present study fills the gap between effect of manufactured nanomaterials (NPs) and their available natural scavengers. In the study,  earthworm Eisenia...

Author(s): Shruti Gupta, Tanuja Kushwah and Shweta Yadav

February 2015

Haemato-pathological effect of dichlorvos on blood picture and liver cells of albino rats

The effect of intraperitonal exposure of dichlorvos an organophosphate (OP) pesticide, on haematology parameters and liver pathology of Wister rats was investigated.  Thirty male albino rats grouped into six (6) of five rats each were injected with 0, 3.7, 7.4, 11.1, 14.8 and 18.5mg/kg of dichlorvos (DDVP) (1 ml/kg) respectively. The haematological parameters measured were red blood cells, haemoglobin; packed cell...

Author(s): Brown Holy, Kenanagha, B   and Onwuli, D.O

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