Effect of Hibiscus sabdariffa anthocyanins on 2, 4-dinitrophenylhydrazine-induced tissue damage in rabbits
April 2010
This study examines the effects of anthocyanin extract of the dried calyces of Hibiscus sabdariffa Linn. on the 2, 4 -dinitrophenylhydrazine (2, 4 -DNPH)-induced cytotoxic effects in rabbits. Twenty male adult rabbits used for the study were divided into four groups. Group 1, the control took only water while animals in groups 2 and 4 received 100 mg/kg body weight of the anthocyanin extract of H....
Wastewater COD removal using sol-gel immobilized humic acid
April 2010
In this study, humic acid which contains both hydrophobic and hydrophilic moieties is successfully entrapped in sol-gel matrix which is used to reduce the chemical oxygen demand (COD) of Gaza wastewater. The method was very efficient in which more than 90% reduction of the COD had been achieved, it was found that contact time with the matrix, temperature, pH, particles size, adsorbent dose, and agitation speed effect...
Organic pollution from the Songhua River induces NIH 3T3 cell transformation: Potential risks for human health
December 2009
Epidemiological investigation has shown that organic contamination of the Songhua River is a risk factor for tumor development among residents who live nearby. A mutagenesis is induced by organic contamination using short-term genotoxic bio-assays. To further investigate the risk of carcinogenic potential to human health, the NIH3T3 cell line was used to examine the induction of transformation by diethyl...
Comparative nephrotoxic effect associated with exposure to diesel and gasoline vapours in rats
December 2009
Comparative effect of exposure to 20.7 ± 5.8 cm3 h-1kg-1m-3 day-1 of diesel and gasoline vapours on the kidney functions was assessed in rats. It was observed that exposure to diesel and gasoline vapours produced a significant increase (P < 0.05) in serum creatinine, urea, BUN, uric acid, glucose and K+; and a significant decrease (P < 0.05) in serum Na+ and Cl- levels. However, the percentage...
Contamination profile of major rivers along the highways in Ondo State, Nigeria
August 2009
The quality of major rivers (Oluwa, Owena, Ogbese and Ose) along the highways in Ondo state, Nigeria were investigated using water, surface sediment and African catfish, Clarias gariepinus, as environmental indicators. Results from the study revealed that some of the water quality constituents exceeded the World Health Organization (WHO) standards for drinking water and water meant for other recreational...
Fluoride and thyroid function in children in two villages in China
August 2009
Prevention of renal toxicity from lead exposure by oral administration of Lycopersicon esculentum
July 2009
For decades, lead (Pb) has being known for its adverse effects on various body organs and systems. In the present study, the ability of Pb to lower renal clearance (RC), as an index of renal function, was investigated and tomato (Lycopersicon esculentum: source of antioxidants) paste (TP) was administered orally to prevent the Pb’s adverse effects. 54 Sprague Dawley rats, randomly divided into 3...
Association of interleukin 27 expression and p28 gene polymorphism with chronic hepatitis B virus infection
July 2009
Interleukin 27 (IL-27) is a newly discovered cytokine encoded by 2 genes, EBI3 and p28. We investigated IL-27 serum levels and p28 gene -964 A>G polymorphism in patients with chronic HBV infection and in healthy individuals, with the aims to define the correlation between IL-27 expression and chronic hepatitis B development. 168 patients, 99 recovered individuals and 152 healthy individuals...
Studies on the pollution potential of wastewater from textile processing factories in Kaduna, Nigeria
July 2009
Samples of effluents from 3 textile processing factories F(1), F(2) and F(3), were characterized for their pollution potential. The concentrations of solids were found to be 1020, 790 and 1,380 mg/l total solids for the factories 1, 2 and 3, respectively. The BOD’s and COD’s were 342.8 and 542.4 mg/l for F(1), 123.2 and 224.6mg/l for F(2) and 456 and 738.4mg/l for F(3). The pH for the effluents...
Characterization of industrial waste and identification of potential micro-organism degrading tributyl phosphate
June 2009
The present research study has been carried out in the waste disposal site for characterization of physical, chemical and biological parameters to assess the microbial consortium present in the contaminated site and to isolate the potential microorganism for biodegradation of Tributyl Phosphate. The ambient conditions present in the contaminated site shows the values: pH (6.61), Temperature (35.6), Moisture (50.72%),...
Hydroxocobalamin (vit b12a) effectively reduced extent of cyanide poisoning arising from oral amygdalin ingestion in rats
June 2009
This study investigated the efficacy of hydroxocobalamin in reducing cyanide toxicity arising from amygdalin administration in rats. Amygdalin at its therapeutic dose (20 mg/kg body weight) was co-administered with hydroxocobalamin to rats at two different levels (25 mg/kg and 50 mg/kg body weight) for 14 days. Symptoms of cyanide toxicity in the blood and liver were monitored in the animals and compared with the...
Diclofenac induced toxic manifestations on adjuvant induced arthritic rats pheripheral and reproductive organ of male wistar rats rattus norvegicus
June 2009
Non-Steroidal Anti-inflammatory Drugs (NSAIDs) are the most frequently prescribed therapeutic agents, used for the treatment of rheumatic diseases, because they have analgesic, antipyretic and anti- inflammatory actions. Diclofenac (Voltaren) is a well-known member of the acetic acid family of NSAIDs, used to reduce inflammation and pain associated with arthritis osteoarthritis, and ankylosing spondylitis. There is...
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