Journal of
Toxicology and Environmental Health Sciences

  • Abbreviation: J. Toxicol. Environ. Health Sci.
  • Language: English
  • ISSN: 2006-9820
  • DOI: 10.5897/JTEHS
  • Start Year: 2009
  • Published Articles: 212

JTEHS Articles

Effect of Hibiscus sabdariffa anthocyanins on 2, 4-dinitrophenylhydrazine-induced tissue damage in rabbits

April 2010

This study examines the effects of anthocyanin extract of the dried calyces of Hibiscus sabdariffa Linn. on the 2, 4 -dinitrophenylhydrazine (2, 4 -DNPH)-induced cytotoxic effects in rabbits. Twenty male adult rabbits used for the study were divided into four groups. Group 1, the control took only water while animals in groups 2 and 4 received 100 mg/kg body weight of the anthocyanin extract of H....

Author(s): A. Ologundudu, A. O. Ologundudu, O. M. Oluba, I. O. Omotuyi and F. O. Obi 

Wastewater COD removal using sol-gel immobilized humic acid

April 2010

In this study, humic acid which contains both hydrophobic and hydrophilic moieties is successfully entrapped in sol-gel matrix which is used to reduce the chemical oxygen demand (COD) of Gaza wastewater. The method was very efficient in which more than 90% reduction of the COD had been achieved, it was found that contact time with the matrix, temperature, pH, particles size, adsorbent dose, and agitation speed effect...

Author(s): Rafik Helles

Organic pollution from the Songhua River induces NIH 3T3 cell transformation: Potential risks for human health

December 2009

Epidemiological investigation has shown that organic contamination of the Songhua River is a risk factor for tumor development among residents who live nearby. A mutagenesis is induced by organic contamination using short-term genotoxic bio-assays. To further investigate the risk of carcinogenic potential to human health, the NIH3T3 cell line was used to examine the induction of transformation by diethyl...

Author(s): Jia-Ren Liu, , Hong-Wei Dong, Xuan-Le Tang, Jia Yu, Xiao-Hui Han, Bing-Qing Chen, Chang-Hao Sun and Bao-Feng Yang

Comparative nephrotoxic effect associated with exposure to diesel and gasoline vapours in rats

December 2009

Comparative effect of exposure to 20.7 ± 5.8 cm3 h-1kg-1m-3 day-1 of diesel and gasoline vapours on the kidney functions was assessed in rats. It was observed that exposure to diesel and gasoline vapours produced a significant increase (P < 0.05) in serum creatinine, urea, BUN, uric acid, glucose and K+; and a significant decrease (P < 0.05) in serum Na+ and Cl- levels. However, the percentage...

Author(s): F. E. Uboh, M. I. Akpanabiatu, J. I. Ndem, Y. Alozie and P. E. Ebong

Contamination profile of major rivers along the highways in Ondo State, Nigeria

August 2009

The quality of major rivers (Oluwa, Owena, Ogbese and Ose) along the highways in Ondo state, Nigeria were investigated using water, surface sediment and African catfish, Clarias gariepinus, as environmental indicators. Results from the study revealed that some of the water quality constituents exceeded the World Health Organization (WHO) standards for drinking water and water meant for other recreational...

Author(s): I. A. Ololade and A. O. Ajayi

Fluoride and thyroid function in children in two villages in China

August 2009

Author(s): Quanyong Xiang, Liansheng Chen , Youxin Liang, Ming Wu and Bingheng Chen

Prevention of renal toxicity from lead exposure by oral administration of Lycopersicon esculentum

July 2009

For decades, lead (Pb) has being known for its adverse effects on various body organs and systems. In the present study, the ability of Pb to lower renal clearance (RC), as an index of renal function, was investigated and tomato (Lycopersicon esculentum: source of antioxidants) paste (TP) was administered orally to prevent the Pb’s adverse effects. 54 Sprague Dawley rats, randomly divided into 3...

Author(s): Salawu Emmanuel O., Adeleke Adeolu A., Oyewo Oyebowale O., Ashamu Ebenezer A., Ishola Olufunto O., Afolabi Ayobami O. and Adesanya Taiwo A.

Association of interleukin 27 expression and p28 gene polymorphism with chronic hepatitis B virus infection

July 2009

Interleukin 27 (IL-27) is a newly discovered cytokine encoded by 2 genes, EBI3 and p28. We investigated IL-27 serum levels and p28 gene -964 A>G polymorphism in patients with chronic HBV infection and in healthy individuals, with the aims to define the correlation between IL-27 expression and chronic hepatitis B development. 168 patients, 99 recovered individuals and 152 healthy individuals...

Author(s): Shiqun Wang, Chengliang Zhu, Rui Zhang, Li Liu and Jianguo Wu

Studies on the pollution potential of wastewater from textile processing factories in Kaduna, Nigeria

July 2009

Samples of effluents from 3 textile processing factories F(1), F(2) and F(3), were characterized for their pollution potential. The concentrations of solids were found to be 1020, 790 and 1,380 mg/l total solids for the factories 1, 2 and 3, respectively. The BOD’s and COD’s were 342.8 and 542.4 mg/l for F(1), 123.2 and 224.6mg/l for F(2) and 456 and 738.4mg/l for F(3). The pH for the effluents...

Author(s): Asia Imohimi Ohioma, Ndubuisi Obejesi Luke and Odia Amraibure

Characterization of industrial waste and identification of potential micro-organism degrading tributyl phosphate

June 2009

The present research study has been carried out in the waste disposal site for characterization of physical, chemical and biological parameters to assess the microbial consortium present in the contaminated site and to isolate the potential microorganism for biodegradation of Tributyl Phosphate. The ambient conditions present in the contaminated site shows the values: pH (6.61), Temperature (35.6), Moisture (50.72%),...

Author(s): Trupti D. Chaudhari, Susan Eapen and M. H. Fulekar

Hydroxocobalamin (vit b12a) effectively reduced extent of cyanide poisoning arising from oral amygdalin ingestion in rats

June 2009

This study investigated the efficacy of hydroxocobalamin in reducing cyanide toxicity arising from amygdalin administration in rats. Amygdalin at its therapeutic dose (20 mg/kg body weight) was co-administered with hydroxocobalamin to rats at two different levels (25 mg/kg and 50 mg/kg body weight) for 14 days. Symptoms of cyanide toxicity in the blood and liver were monitored in the animals and compared with the...

Author(s): O. I. Oyewole and E. T. Olayinka

Diclofenac induced toxic manifestations on adjuvant induced arthritic rats pheripheral and reproductive organ of male wistar rats rattus norvegicus

June 2009

Non-Steroidal Anti-inflammatory Drugs (NSAIDs) are the most frequently prescribed therapeutic agents, used for the treatment of rheumatic diseases, because they have analgesic, antipyretic and anti- inflammatory actions. Diclofenac (Voltaren) is a well-known member of the acetic acid family of NSAIDs, used to reduce inflammation and pain associated with arthritis osteoarthritis, and ankylosing spondylitis. There is...

Author(s): Sambandam Subramanian

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