Journal of
Toxicology and Environmental Health Sciences

  • Abbreviation: J. Toxicol. Environ. Health Sci.
  • Language: English
  • ISSN: 2006-9820
  • DOI: 10.5897/JTEHS
  • Start Year: 2009
  • Published Articles: 197

JTEHS Articles

January 2015

Phorate poisoning of a leopard (Panthera pardus) in the Nilgiris

India is an agricultural country; animal husbandry has always been associated with agriculture. People still thrive upon animal products such as milk, meat and manure intensely for their essentialities. India has a huge cattle population and most of them graze in areas close to forests and their fringes competing for their pastoral needs with other wild animals. This then leads to human-wildlife conflicts, which tends...

Author(s): Boon Allwin and Stalin Vedamanickam

January 2015

Evidence of micronuclei in fish blood as a biomarker of genotoxicity due to surface run off agricultural fungicide (Propiconazole)

Micronuclei, nucleoplasmic bridges and nuclear buds are biomarkers of genotoxic events and chromosomal instability. In laboratory, these genome damages can be measured easily. The measurement of cytogenetic alterations in-vivo has considered an initial step in the risk assessment procedures by genotoxic agents. In fishes, micronucleus assay has shown useful in vivo techniques for genotoxicity testing, and potential for...

Author(s): Pallavi Srivastava and Ajay Singh

December 2014

Ameliorative effect of seed extract of Pterocarpus santalinus on coragen induced haematological alterations and serum biochemical changes in Charles Foster rats

In the present study, the ameliorative effect of an aqueous extract of Pterocarpus santalinus against coragen induced haematological changes, biochemical alterations and oxidative damage in Charles foster rats was undertaken. Coragen administration (1000 mg kg-1 body weight orally for 6 weeks) was associated with significant rise in serum levels of alkaline phosphatase, urea, uric acid and creatinine and enhanced lipid...

Author(s): Khushboo Dutta, Mohammad Ali, Azim Najam, Ranjit Kumar and Arun Kumar  

December 2014

Naturally contaminated feed with low levels of fumonisins with anti-mycotoxin additive and its impact in the immune cells and blood variables in broiler chickens

Ninety six one-day-old broiler chickens were used to evaluate the effect of feeding naturally contaminated rations with low levels of fumonisins (FBs) and the protective effect of a commercial anti-mycotoxin additive (AMA) on circulating and intestinal immune cells, blood biochemistry, hematological variables and biomarkers of FBs exposure. Birds were assigned in three groups: Negative control (NC), positive control...

Author(s): Pedro Celso Machado Júnior, Breno Castello Branco Beirão, Tobias Fernandes Filho, Max Ingberman, Celso Fávaro Júnior, and Luiz Felipe Caron,  

November 2014

Occurrence of some pesticides in Bhoj wetland Bhopal and their effect on phytoplankton community: An ecological perspective

The present communication deal with the analysis of water samples from Bhoj wetland to detect three pesticides (chlorpyrifos, monocrotophos and endosulfan) and to assess their individual toxicity to the phytoplankton community. Higher concentration of most of the pesticides was found to be in the pre-monsoon (March to May) 0.9 µg/l (monocrotophos) and post-monsoon (September to December) 1 µg/l...

Author(s): Ayaz A. Naik and Wanganeo A.

November 2014

The use of planktons as tools for monitoring water quality in oil polluted streams of the Niger Delta, Nigeria

The Niger Delta ecosystems of Nigeria, typically consisting of mangrove swamps and riparian forests, have come under threat in the last six decades as a result of environmental pollution from oil exploration, drilling, refining and transportation. This study examines two Niger Delta streams (Ogba Evie and Otor) to ascertain the extent of hydrocarbon and heavy metal pollution and the status of the biotic communities in...

Author(s): Amaeze Nnamdi Henry and Onyema Ikenna Charles  

October 2014

Determination of the effects of some artificial sweeteners on human peripheral lymphocytes using the comet assay

In this study, the genotoxicity of the artificial sweeteners acesulfame potassium, aspartame, saccharin, and sorbitol, which are used in food industry and by patients with diabetes, was investigated in human peripheral lymphocyte cells using the single-cell gel electrophoresis (comet) technique. Human lymphocyte cells were treated with the substances for three hour at each of the three dosages (1.25, 2.5, and 5 ppm)....

Author(s): Zeynep Fındıklı and Şifa Türkoğlu

October 2014

Bioaccumulation of heavy metals in cane rat (Thryonomys swinderianus) in Ogun State, Nigeria

Wild animals have provided complimentary protein for human populations across the world over the centuries. This study investigated on bioaccumulation of heavy metals in different organs of cane rat (Thryonomys swinderianus) and the health implications of its consumption. Four carcasses were collected from each of the four ecotomes (Mosinmi, Agbara, Omo forest reserve and Ibese) and concentrations of 7 heavy metals (Fe,...

Author(s): Durojaye A. Soewu, Olufemi M. Agbolade, Rasheed Y. Oladunjoye and Ibukun A. Ayodele

October 2014

Effect of dipentyl phthalate in 3-dimensional in vitro testis co-culture is attenuated by cyclooxygenase-2 inhibition

Exposure to phthalate esters is associated with changes in steroidogenesis, leading to the hypothesis that this is a primary mechanism of phthalate reproductive toxicity. However, some phthalate-induced male reproductive toxicity has been demonstrated in the absence of changes to testosterone production, suggesting additional mechanisms of action. There is evidence that phthalate exposure increases expression of the...

Author(s): Susanna Wegner, Xiaozhong Yu, Hee Yeon Kim, Sean Harris, William C. Griffith, Sungwoo Hong and Elaine M. Faustman

September 2014

Mitigating potential and antioxidant properties of aqueous seed extract of Leea guineensis against dichlorovos-induced toxicity in Wistar rats

  This work was carried out to access the mitigating potential of Leea guineensis aqueous seed extract against dichlorovos (DDVP)-induced toxicity in Wistar rats for ten days. Twenty Wistar albino rats (weighing 90 to 106 g) were divided into four groups (Normal, DDVP-induced untreated, DDVP-induced treated with 200 mg/kg of L. guineensis seed and DDVP-induced treated with 400 mg/kg L. guineensis seed by oral...

Author(s):   Ajiboye B.O., Salawu S.O., Okezie B., Oyinloye B.E., Ojo A.O., Onikanni S.A., Oso A.O., Asoso O.S. and Obafemi T.O.

September 2014

Identification and quantification of heavy metals in local drinks in Northern Zone of Nigeria

  Nine heavy metals were studied in locally prepared drinks, namely, “Zobo” and “Kunnu Zaki”. The samples were prepared from the outer covering (calyx) of the fruits of roselle Hibiscus sabdariffa and cereals (millet or guinea corn), respectively. Twenty samples of “Zobo” coded Zb1-Zb20 and twenty samples of “Kunnu Zaki” coded Kz1-Kz20 were bought from different...

Author(s):   Bakare-Odunola M. T. and Mustapha K. B.

August 2014

Response of liver and gills of Mystus gulioto the heavy metal pollutants and metacercarian infection

  Mystus gulio collected from the polluted waters of Veli lake in the Thiruvananthapuram district of Kerala, India was subjected to histopathological observations to study the effect of the pollutants on the tissue of the fishes. The epithelial layer of the secondary lamellae was lifted and detached from the underlying tissue, and was also seen in a degenerative form. The hepatocytes have lost their shape and...

Author(s):   Sherly Williams E., Beena V. S., Razeena Karim L. and Seethal Lal S.

July 2014

1,1,1-Trichloro-2,2-bis(p-chlorophenyl)ethane (DDT) and its derivatives in marketed Clarius werneri caught from Uganda’s major urban wetlands

The presence of 1,1,1-trichloro-2,2-bis(p-chlorophenyl)ethane (DDT) and derivatives in the Clarius werneri of Uganda’s major urban wetland ecosystems was investigated. Solid dispersion extraction method for extraction, florisil column method for clean-up, gas chromatograph equipped with an electron capture detector (GC-ECD) for analysis and gas chromatograph equipped with mass spectrophotometer (GC-MS) for...

Author(s): Proscovia Nnamuyomba, Jolocam Mbabazi and Muhammad Ntale

May 2014

Whole lung lavage therapy: Treatment for lung injury caused by paraquat poisoning

Paraquat poisoning is characterized by multi-organ failure and pulmonary fibrosis with respiratory failure, resulting in high mortality and morbidity. To serious paraquat patients, the effectiveness of conventional treatments is unsuccessful. Whole lung lavage is a technique that was developed in the 1960s with the purpose of removing lipoproteinaceous material that accumulates in the bronchi of patients with alveolar...

Author(s): Baotian Kan, Xiangdong Jian, Zhongchen Zhang, Qian Zhou, Jieru Wang, Guangcai Yu and Jing Sun

May 2014

Bisphenol A induced reactive oxygen species (ROS) in the liver and affect epididymal semen quality in adults Sprague-Dawley rats

Reactive oxygen species (ROS) generation, induced by Bisphenol A (BPA) may cause mammalian sperm damage according to research findings. BPA is a known contaminant that with increased exposure in the body can exert both toxic and estrogenic effects in mammalians cells. The aim of this study was to evaluate the effect of BPA-induced oxidative stress in the liver on epididymal semen quality in adult rat. BPA was mixed in...

Author(s): Ansoumane Kourouma, Duan Peng, Quan Chao, Yaima M. Lopez T, Liu Changjiang, Wang Chengmin, Fu Wenjuan, Qi Suqin, Yu Tingting and Yang Kedi

March 2014

Development of urea formaldehyde and polystyrene waste as copolymer binder for emulsion paint formulation

Urea formaldehyde, that is, trimethylol urea (TMU) resin was synthesized and blended with polystyrene waste (PS) to develop TMU/PS copolymer binder for emulsion paint formulation. The resulting copolymer was analysed for formaldehyde emission and other physical properties such as viscosity, gel time, density, turbidity, refractive index, melting point and moisture uptake, elongation at break and solubility in water....

Author(s): Osemeahon S. A. and Dimas B. J.

March 2014

Characterization of chrome buffing dust (CBD) generated from NILEST tannery associated with pathogenic fungi

An attempt was made to monitor the level of chromium from chrome buffing dust waste (CBD) from Nilest tannery through preliminary investigation of the physicochemical characteristic of dried buffing dust (CBD) waste: pH, temperature (°C), alkalinity (mg/L), ash content (%), crude fibre (%) for example, using effluent and reference water sample as (control). Comparative study of the mean values of CBD, effluent and...

Author(s): S. D. Emmanueul, I. K. Adamu, A. Ejila, M. I. Ja’afaru, A. Yabaya and B. Habila

February 2014

Taurine alleviated biochemical alterations in male Wistar rats co-exposed to chlorpyrifos and lead

The aim of the study was to investigate the effects of taurine on biochemical parameters in male Wistar rats co-exposed to chlorpyrifos and lead. Fifty rats were divided into five groups of ten rats each. The distilled water (DW) group received distilled water and the soya oil (SO) group received soya oil (1 ml/kg). Other groups were treated sequentially with taurine (50 mg/kg), chlorpyrifos (4.25 mg/kg, 1/20th LD50)...

Author(s): Motunrayo Ganiyat Akande, Yusuf Otaru Aliu, Suleiman Folorunsho Ambali and Joseph Olusegun Ayo

February 2014

Undesirable effects of drinking water chlorination by-products

The fundamental objective of water treatment is the protection of consumers from pathogenic microorganisms. Chlorination of drinking water is essential to prevent waterborne disease. However, chlorine reacts with organic matter present in surface waters to form various by-products suspected of being carcinogenic. In the last decade, several epidemiological studies have been conducted to determine the connection between...

Author(s): Khallef Messaouda, Merabet Rym and Benouareth Djamel Eddine

February 2014

Histopathological and hormonal disrupting effects of Escravos crude oil on the ovary of Chinchilla rabbits

Crude oil is found in water and soil due to pollution resulting from oil exploration and exploitation. It is used as traditional medicine in some countries, especially among rural dwellers in the south-south and south-eastern Nigeria. The aim of this study was to investigate the effects of Escravos crude oil on serum cholesterol, estradiol and progesterone in the ovary of Chinchilla rabbits. A total of thirty female...

Author(s): Okoye Jude Ogechukwu, Ngokere Anthony Ajuluchukwu, Ogenyi Samuel Ifedioranma and Onyemelukwe Anulika Obianuju

January 2014

Coco peat - An alternative artificial soil ingredient for the earthworm toxicity testing

The artificial soil medium recommended for invertebrate toxicity studies by OECD and ISO contains sphagnum peat as an organic component. Sphagnum peat is not widely available in tropical countries especially in the Indian subcontinent. Importing of sphagnum peat is not economically feasible and also time consuming Using of native organic matter source is also much more ecologically relevant for the region. Hence,...

Author(s): R. Shanmugasundaram, T. Jeyalakshmi, Sweatha S. Mohan, M. Saravanan, A. Goparaju and P. Balakrishna Murthy

January 2014

Antibiogram of food-borne pathogens isolated from ready-to-eat foods and Zobo Drinks Sold Within and Around PRESCO Campus of Ebonyi State University (EBSU), Abakaliki, Ebonyi State, Nigeria

Food poisoning (food-borne disease) is an infection that occurs after consuming food contaminated by sufficient numbers of viable pathogens and their toxins. It is a common and costly preventable infection that is of public health concern, and which is treated with available antibiotics. Jellof-rice, abacha, moi-moi and zobo drinks are some ready-to-eat foods sold within the PRESCO campus of Ebonyi State University...

Author(s): Iroha Ifeanyichukwu, Afiukwa Ngozi, Nwakaeze Emmanuel, Ejikeugwu Chika, Oji Anthonia and ILang Donathus

December 2013

Bacterial quality control of domestic and imported brands of bottled water in Saudi Arabia

Water is one of the most abundant and essential commodities of man occupying about 70% of the earth’s surface and 60% of the human body therefore it should be continuously protected against microbial infections. Also, the mineral content in drinking water should be maintained within the acceptable range. Quality control of drinking water emerged with the invention of bottled drinking water. In this study, samples...

Author(s): Amal A. Al Hazzani, Laila W. Al Farra, Amal Asran, Afaf I. Shehata and Nadine M. S. Moubayed

December 2013

Maternal lead exposure and pregnancy outcome in Wistar albino rats

Lead (Pb) is a heavy metal environmental pollutant and toxicant. The present study investigated dose-related effects of maternal Pb exposure on pregnancy outcome. Wistar albino rats were gavaged with Pb nitrate (4 or 8 mg/kg) or vehicle daily from gestation day 0 until delivery. Length of pregnancy was noted. Number, birth weight and physical characteristics of pups were registered. Neonatal mortality was also recorded...

Author(s): J. S. Aprioku and I. M. Siminialayi

September 2013

Effect of some pesticides on growth, nitrogen fixation and nifgenes in Azotobacter chroococcum and Azotobacter vinelandii isolated from soil

This study was designed to evaluate the effects of three pesticides (Imazetapir, Dimethoate and Bayleton 50) at the recommended concentration (in the field), on the growth of pure cultures ofAzotobacter chroococcum and Azotobacter vinelandii, on the amount of fixed nitrogen and nifgenes. Herbicide Imazetapir had no negative effect on nitrogen fixing bacteria, while Dimethoate and Bayleton 50 exhibited...

Author(s): Aras Mohammed Khudhur, and Kasim Abass Askar

September 2013

Estimation of toxic effects of chemically and biologically synthesized silver nanoparticles on human gut microflora containing Bacillus subtilis

Biological silver nanoparticles were successfully synthesized from a simple green and natural route using the extract of Allium cepa (onion) with the use of silver nitrate as precursor and chemically synthesized using silver nitrate and tri sodium citrate. Nanoparticle synthesis was proven under UV-Visible absorption spectroscopy. Toxicity of sliver nanoparticles was tested using ToxTrak test, in which, fresh...

Author(s): Pankaj K. Tyagi, Shruti Tyagi, Charul Verma and Aanchal Rajpal

September 2013

GST polymorphic status modifying the arsenic induced clinical manifestations in people of the southern part of West Bengal, India

Persons chronically exposed to environmental arsenic through their drinking water experience various arsenic induced clinical manifestations which includes keratosis and pigmentary changes in the skin. However the response varies widely among persons. To study whether Glutathione-S-Transferase (GST) gene polymorphism plays any role in this variation, a total of 78 study subjects were recruited from the villages of...

Author(s): Sarmishtha Chanda, Bhaswati Ganguli, Uma B. Dasgupta and Debendranath Guha Mazumder,

  • Article Number: A882A151564

August 2013

Induction of oxidative stress and apoptosis in human neutrophils by p-phenylenediamine

Exposure to paraphenylenediamine (PPD), a derivative of paranitroaniline widely used as an oxidisable hair dye, is often associated with the development of allergic contact dermatitis. Such reactions involve activation of the subject’s immune system and it is known that neutrophils are the first cells to arrive at the site of perturbation. In view of its pivotal role in the initiation and amplification of...

Author(s): Zineb Elyoussoufi, Norddine Habti, Khadija Mounaji, Said Motaouakkil, and Rachida Cadi

August 2013

A comparative study of copper (ii) removal on iron oxide, aluminum oxide and activated carbon by continuous down flow method

The adsorption capacities of iron oxide, aluminum oxide, and activated carbon sorbents for the removal of copper ions were compared by down flow method. For this purpose, the 20 mg L-1aqueous solution of Cu (II) with initial pH of 6.5 was fed through three different packed columns at bed depth of 10 cm and flow rate of 1.85 ml min-1. The experimental breakthrough curves were drawn from the adsorption data of packed bed...

Author(s): Mohammad Hossein Salmani, Mahmoud Vakili and Mohammad Hassan Ehrampoush

August 2013

Lead and cadmium in maternal blood and placenta in pregnant women from a mining-smelting zone of Peru and transfer of these metals to their newborns

The present study was carried out to determine the lead and cadmium concentration in maternal and umbilical cord blood and placental tissue and breast milk, evaluating forty deliveries with normal evolution of pregnant women living in a mining-smelting town in Peru. In this study, mean concentration of lead in the blood of both women and their neonates were 27.2 ± 15.9 and 18.5 ± 13.0 µg/dl,...

Author(s): Castro Jorge, López de Romaña Daniel, Bedregal Patricia, López de Romaña Guillermo, Chirinos Doris

July 2013

The protective role of 3-aminothiazolo[3-2a]benzimadzole-2-carbonitrile against lung and colon injury induced by nitrosomorpholine in adult male albino rat

Nitrites and morpholine are ubiquitous environmental contaminants found in drinking water and food. NMOR can be formed endogenously from nitrite and morpholine. Increased levels of reactive oxygen species/ reactive nitrite species (ROS/RNS) are involved in the mechanism of NMOR toxicity. Certain antimicrobial, antifungal and antioxidant potential were observed in heterocyclic benzimidazole derivatives and dimethyl...

Author(s): Hossam El-Din M. Omar, Heba M. Saad El-Din, Elham A. Abd-Allah and Abdelwareth A. O. Sarhan

July 2013

Modulatory effects of kolaviron (Garcinia kola extract) on spermogram and reproductive system of adult male wistar rats in lead acetate induced toxiocity

This study was designed to determine the effects of the concomitant administration of kolaviron (Garcinia kola extract) with lead on male fertility by evaluating some spermogram and histopathology of the testis. 20 adult male Wistar rats were randomly divided into 4 groups of 5 rats each. The rats in group O (negative control) were given normal saline, while rats in group A were given 6 mg/kg body weight of lead...

Author(s): Jegede Ayoola Isaac, Ajadi Mary Bolanle and Akinloye Oluyemi,

July 2013

Metals bioavailability in the leachates from dumpsites in Zaria Metropolis, Nigeria

Landfill leachates pose a significant threat to both surface water and groundwater especially the wells adjacent to landfills. The study investigated the bioavailability of zinc (Zn), copper (Cu), lead (Pb), cadmium (Cd) and mercury (Hg) from leachates of ten huge dumpsites across the metropolitan city of Zaria. The trends in the mean concentrations of the metals (mg/L) among the fractions were; Zn: total > mobile...

Author(s): Sani Uba, Adamu Uzairu, Muhammad Sani Sallau, Hamza Abba and Okunola Oluwole Joshua

June 2013

The challenge of future landfill: A case study of Malaysia

Landfilling is the most frequent waste disposal method worldwide. It is recognised as being an important option both now and in the near future, especially in low- and middle-income countries, since it is the easiest and the cheapest technology available. Owing to financial constraints, landfills usually lack of environmental abatement measures, such as leachate collection systems and lining materials. As a result, a...

Author(s): Sharifah Norkhadijah Syed Ismail, and Latifah Abd. Manaf

June 2013

Effects of gas flaring on rainwater quality in Bayelsa State, Eastern Niger-Delta region, Nigeria

The aim of the paper was to study the spatial effects of gas flaring on rainwater quality in Bayelsa State, Eastern Niger-Delta, Nigeria. The physicochemical variables were isolated from the analysis of rainwater samples from eight locations in the State, while mean monthly rainfall data for 2011 of the selected areas was collected from the Port Harcourt International Airport which has a distance of 15 km to the...

Author(s): E. E. Ezenwaji, A. C. Okoye and V. I. Otti

June 2013

Acute toxicity test of two pesticides diazinon and deltamethrin on spirlin (Alburnoides bipunctatus) larvae and fingerling

The present research was performed to determine and compare acute toxicity of diazinon and deltamethrin to spirlin larvae and fingerling. Diazinon and deltamethrin are common useful agricultural pesticides. LC50 of 24, 48, 72 and 96 h was attained by probit analysis software SPSS Version 16. Fish samples (21 fish in each test group) were exposed to different...

Author(s): Mohammad Forouhar Vajargah, Sayede Amene Hossaini and Aliakbar Hedayati

May 2013

Prevention of acute ammonia toxicity in bluga (Huso huso), using natural zeolite

The research was accomplished in order to study the efficiency of natural zeolite to prevent acute toxicity of ammonia on Huso huso. The study was performed using Water static method for 96 h. Fish with average weight 46 ± 5 g and total length 22 ± 4 cm were exposed to four different concentrations (15, 30, 50, 75 mg L-1) of ammonia salt. A group of fish was considered as control. Under stable...

Author(s): Mohammad Farhangi, Hosna Gholipour-Kanani, and Faramarz Rostami-Charati

May 2013

Pesticides-induced oxidative damage: Possible in vitro protection by antioxidants

This study was designed to investigate the effect of selenium (Se) and a combination of vitamin E (VE) vitamin C (VC) on pesticides induced biochemical alterations in rat erythrocytes and hepatocytes in vitro. Vitamin E and C and selenium are potential antioxidants, known to be able to protect cells against oxidative damage. In vitro changes in antioxidant systems and protective role of selenium and a...

Author(s): Ahmed K. Salama, Khaled A. Osman and Omran A. Omran

April 2013

Comparison of World Trade Center dust with zinc acetate and lead oxide combinations to determine damage to human lung cells

The exposures of the World Trade Center (WTC) dust of the September 11, 2001 tragedy are linked to increased respiratory problems and emergence of World Trade Center Cough. Zinc (Zn) and Lead (Pb) are among the many heavy metals found in WTC dust. Synergistic effects among several chemicals might be contributing to respiratory illness. The individual toxicity, and combination treatments of Pb and Zn at a particular...

Author(s): Niharika Pattnaik and Ann Marie DiLorenzo

April 2013

A spectrophotometric method for quantification of sulphite ions in environmental samples

This study described an alternative method developed for the quantification of sulphite ions in environmental samples. The method was based on results of an investigation of the reaction of excess pentacyanidonitrosylferrate(II) popularly known as nitroprusside (NP) and the sulphite anion. NP-SO32- reaction product by use of zinc-ethylenediamine complex cation(s) was stabilized. The NP-SO32-  reaction...

Author(s): Peter Musagala, Henry Ssekaalo, Jolocam Mbabazi and Muhammad Ntale

March 2013

Opposite effects of Ca2+ on toxicity by CdCl2 on white blood cells (WBC), protein level and LD50 of rabbits Oryctolagus cuniculus

Heavy metals and their derivatives are a special class of toxic substances. Many metals are useful for industrial, agricultural and medical applications. Indeed, they can go back through the food chain and thus achievable to human being. Our aim is to study an example of heavy metals cadmium (CdCl2) at two concentrations 30 and 60 ppm on biological model Oryctolagus cuniculus that is often used in...

Author(s): Rachid Rouabhi, Bouchiha Hanene, Bouchama Khaled, Berrebbah Houria and Djebar MohamedReda

March 2013

Inclusion of incorrect information on snakebite first aid in school and university teaching materials in Nepal

In previous studies in Nepal, snakebite victims were found to either not have Pressure Immobilization Bandaging (PIB) or Local Compression Pad Immobilization (LCPI) performed for first aid, or had it performed incorrectly. The goal of this study was to evaluate training texts regarding first aid measures for snakebite and the rates of performance of both methods currently recommended, as well as ineffective or harmful...

Author(s): Deb P. Pandey, and Bishnu P. Khanal,

March 2013

Correlation between glutathione S-transferase Mu 1 (GSTM1) and glutathione S-transferase pi gene (GSTP1) polymorphisms and markers of inflammatory stress in pregnant females

The Mother and Child Environmental Cohort (MACE) study piloted in South Africa in 2010 to 2011, collected genetic, biochemical and clinical data from pregnant females residing in south and north Durban. We evaluated birth outcomes and the influence of GSTM1pos→GSTM1null and theGSTP1 (Ile105Val; AA→AG/GG) polymorphisms on the extent of DNA damage and with biomarkers [glutathione (GSH) and...

Author(s): Poovendhree Reddy, Rajen N. Naidoo, Anil Chuturgoon, Kareshma Asharam, Dhaneshree Naidoo, Alisa Phulukdaree and Shivona Gounden

February 2013

Water and sanitation situation in Nima and Teshie, Greater Accra Region of Ghana

This study examined the water and sanitation (WATSAN) situation in Nima and Teshie, Greater Accra Region of Ghana. A number of research instruments and methods of primary and secondary data collection were employed. These were focus group discussions (FGD), field observation, and interviews. Data collected were edited, coded, and analyzed with the aid of Statistical Package for Social Scientists (SPSS) to...

Author(s): Doris A. Fiasorgbor

February 2013

Non-cancer risk assessment from exposure to mercury (Hg), cadmium (Cd), arsenic (As), copper (Cu) and lead (Pb) in boreholes and surface water in Tinga, in the Bole-Bamboi District, Ghana

The study assessed non-cancer human health risk from exposure to mecury (Hg), cadmium (Cd), arsenic (As), copper (Cu), and lead (Pb) in surface and groundwater in Tinga, in the Bole-Bamboi District. A total of 42 water samples were collected for a period of six months. Mean concentration of Hg, Cd, and Pb were found to be (0.050 ± 0.04 mg/L), (0.031 ± 0.02 mg/L) and (0.07 ± 0.05 mg/L), respectively....

Author(s): Samuel Jerry Cobbina, Daniel Nkuah, Damian Tom-Dery and Samuel Obiri

January 2013

Environmental metals pollutants load of a densely populated and heavily industrialized commercial city of Aba, Nigeria

Diseases and their associated health defects are most often related to the quality of the total environment which in itself is also related to the quality and quantity of wastes generated in those areas, as partly defined by the nature of activities carried out by the populace. This environment-health relationship dynamics are particularly evident in most tropical environments like Nigeria where various environmental...

Author(s): Tobias I. Ndubuisi Ezejiofor, A. N. Ezejiofor, A. C. Udebuani, E. U. Ezeji, E. A. Ayalogbu, C. O. Azuwuike, L. A. Adjero, C. E. Ihejirika, C. O. Ujowundu, L. A. Nwaoguand K. O. Ngwogu

January 2013

Determination of median lethal concentration (LC50) of copper sulfate and lead nitrate and effects on behavior in Caspian sea kutum (Rutilus frisii kutum)

The aim of present study was to determine the LC50 value of in Caspian sea kutum. The results indicated that median lethal concentration (LC50) of Caspian sea kutum (Rutilus frisii kutum) for 24, 48, 72 and 96 h of exposure are 2.944, 2.756, 2.562 and 2.310 ppm, respectively and median lethal concentration (LC50) of lead to Caspian sea kutum (R. frisii kutum) for 24, 48, 72 and 96 h of exposure as...

Author(s): Esmail Gharedaashi, Mohammad Reza Imanpour and Vahid Taghizadeh

January 2013

Toxicological assessments of the aqueous extract of Boswellia dalzielli stem bark on the liver and kidney of male mice

The study was conducted to determine the phytochemical constituents and also to assess the toxicity of the aqueous extract of Boswellia dalzielli stem bark on the liver and kidney of male mice. Healthy male mice weighing between 45 to 50 g were used. The mice were grouped into four different groups, each containing four mice, respectively. Different concentrations (200, 400 and 600 mg/kg) of the aqueous...

Author(s): L. J. Goje, P. E. Ghamba, D. N. Bukbuk and I. Lai

December 2012

Cytogenotoxicity effects of industrial effluents on Allium cepa root meristem: A review on positive results and problems of effective compliance to environmental legislations; the Nigeria perspective

Most industries are sited with little or no consideration for environmental and social consequences, especially in developing countries. This has led to the discharge of genotoxic chemicals used for many purposes in the manufacturing processes into environmental compartments such as air, water, soil and sediments. Results of the cytotoxic and genotoxic assays of these wastewaters on Allium cepa root tip...

Author(s): Abu Ngozi E.

December 2012

Effect of lead nitrate on survival rate and chronic exposure on growth performance of grass carp (Ctenopharyngodon idella)

The acute toxicity of lead nitrate to grass carp (Ctenopharyngodon idella) juveniles was assessed in a static renewal bioassay for 96 h. In addition, an experiment was conducted to determine the growth performance during 60-day sublethal (Pb(NO3)2) exposure. The results indicated that median lethal concentration (LC50) of lead nitrate to Grass carp for 96 h of exposure was 246.455 µ. The chronic exposure to...

Author(s): Esmail Gharedaashi, Hamed Nekoubin, Alireza Asgharimoghadam, Mohammad Reza Imanpour and Vahid Taghizade

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