African Journal of
Pharmacy and Pharmacology

  • Abbreviation: Afr. J. Pharm. Pharmacol.
  • Language: English
  • ISSN: 1996-0816
  • DOI: 10.5897/AJPP
  • Start Year: 2007

AJPP Articles in press

A review on chemical and pharmacological profile of a novel class of antihyperglycemic drugs: Dipeptidyl protease-4 inhibitors

Article in Press

The dipeptidyl peptidase-4 (DPP-4) inhibitors are a new class of anti hyperglycemic agents which were developed for the treatment of type-2 diabetes mellitus by rational drug design, based on an understanding of the mechanism of action and knowledge of the structure of the target enzyme. Glucagon-like peptide-1 (GLP 1) and gastric inhibitory polypeptide (GIP) are hormones secreted by the enteroendocrine cells of the gut in...

Author(s):Himanshu Joshi, Abdul Wadood Siddiqui, Zia Ur Rehman, Afrin Salma and Deepanshu Sharma

FORMULATION AND EVALUTION OF ORAL FAST DISSOLVING FILM OF FEXOFENADINE HYDROCHLORIDE BY QbD APPROACH

Article in Press

The objective of the present investigation was to formulate, evaluate and optimize oral film of Fexofenadine HCl using (Box Behnken) design. In the present investigation an attempt was made to develop mouth dissolving films of Fexofenadine HCl to achieve fast disintegration and dissolution characteristics with improved bioavailability by oral route. Oral films of Fexofenadine HCl were formulated using HPMC E15 premium...

Author(s):Bhusnure O.G

In vivo assessment of the antipyretic activity of tilmicosin

Article in Press

The aim of the present study was to assess the antipyretic activity of the macrolide antibiotic, tilmicosin, at dose levels of 20 and 40 mg/kg of body weight, subcutaneously, in Brewer's yeast-induced fever model in mice. Pyrexia was induced by subcutaneous injection of 20 mL/kg of 20% (w/v) Brewer’s yeast suspension into the animal’s scruff region. Eighteen hours later, feverish animals were treated with either tilmicosin...

Author(s):A. M. El-Mahmoudy, I. M. Gheith, A. A. Elmajdoub and S. K. Awidat

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