Journal of
Medicinal Plants Research

  • Abbreviation: J. Med. Plants Res.
  • Language: English
  • ISSN: 1996-0875
  • DOI: 10.5897/JMPR
  • Start Year: 2007

JMPR Articles in press

Article in Press

The Effect of Chloroform Extract of Chasmenthera dependens Roots on some Liver marker enzymes on Carbon Tetrachloride (Ccl4) Induced Hepatotoxicity in Wistar Albino Rats.

This study evaluated the phytoconstituents of the chloroform extract of Chasmenthera dependens (C. dependens) roots and the effect of the extract on the liver serum/homogenate enzyme activities of carbon Tetrachloride Induced hepatoxicity in Wistar Albino Rats. Twenty-four (24) female albino rats were used for this study and were divided into groups of four rats each: Groups I rats were normal control. Hepatotoxicity was...

Author(s):CHIOMA ASSUMPTA ANOSIKE, JUSTUS NMADUKA NWACHUKWU, CHINEDU SAMUEL OGBOZOR, CHIDI AUGUSTINE MADUEKEU

Article in Press

Ethnobotanical study of indigenous knowledge on medicinal plants used to treat diseases in selected districts of Amhara regional state, Ethiopia

This study was conducted in four districts of Amhara region, Ethiopia. The aim of the study was to assess medicinal plants found in Menz gera, Siyadebirna Wayu, Antsokiya gemza and Bugna districts, Amhara region, Ethiopia. The ethnobotanical surveys were carried out from September 2017 to June 2018 using a semistructured checklist consisting questions or issues prepared in advance. Two separate questionnaires were...

Author(s):Tewodros Kelemu, Mohammed Said

Article in Press

A Review of the Ethnomedicinal uses of pteridophytes for treating various human ailments in India

Pteridophytes present significant evolutionary innovations such as development of true conducting system with xylem and phloem and dominant saprophytic phase. Pteridophytes are frequently used as ornamental plants because of the green long lasting large foliage and sturdy plant forms. They are being used as bio-indicators for pollution, phytoremediators, and some used as bio-fertilizers. During the invasion of land...

Author(s):Uniyal

Article in Press

Bio-guided anti-cariogenic and phytochemical valorization of Guiera senegalensis and Pseudocedrela kotschyi stem extracts

The objective assigned to the present study is the bio-guided phytochemical investigation of Guiera senegalensis and Pseudocedrela kotschyi stem extracts, two plants used as toothpicks in oral hygiene. The inhibition test revealed a bacteriostatic effect of hexane extract PK1 of P. Kotschyi against Streptococcus mutans ATCC 25175 and Streptococcus salivarius ATCC 20560, two bacterial cariogenic strains, with a decrease...

Author(s):KADJA AMANI BRICE

Article in Press

Comparative analysis of capsaicin in twenty nine varieties of unexplored Capsicum and its antimicrobial activity against bacterial and fungal pathogens

In this study, the capsaicin content of chile pepper extracts from 29 unexplored varieties of Capsicum (twenty five varieties of C. chinense and five of C. annuum) was quantified and correlated with the antimicrobial potential against bacterial and fungal pathogens. The capsaicin content and bactericidal activity against numerous human pathogens (Salmonella, Escherichia coli O157:H7, Listeria monocytogenes,...

Author(s):Morrine Omolo, Zen-Zi Wong, Weih Borh, Grant Hedblom, Kamal Dev and David Baumler

Article in Press

Effect of aqueous extract of Ocimum gratissimum on acetaminophen induced renal toxicity in male wistar rats

ABSTRACT The need for an alternative means of managing renal toxicity has become necessary instead of kidney transplant.. This study investigated the effect of aqueous extract of Ocimum Gratissimum (AEOG) on acetaminophen (ACE) induced renal toxicity. Twenty-five male wistar rats were assigned into five groups (1, 2, 3, 4, 5) of five rats each. Group 1 served as the normal control and received normal saline as placebo....

Author(s):Adaobi Okerulu, Celestine Ani, Jide Uzoigwe, Pamela Okorie, Uzoma Igwe,Choice Nworgu, Deborrah Francis, Anthony Udim

Article in Press

Hepato-Protective Potentials of Sterculia Setigera Stem-bark Extract On Acetominophen Induced Hepato Toxicity In Wistar Albino Rats

The work was set to investigate the potency of stem bark extract of Sterculia setigera as a hepato-protective agent against acute administration (overdose) of acetaminophen in experimental animals. Experimental animals were grouped into six treatments with each group containing five rats. Group 1 was the placebo, group II was the standard treatment orally administered acetaminophen at a dosage of 250mg/kgbw and...

Author(s):

Article in Press

Antibacterial and antioxidant potential of Albizia anthelmintica as a medicinal plant on pathogenic veterinary isolates

Albizia anthelmintica is a medicinal plant belonging to the Fabaceae family. It is widely used by smallholder farmers and pastoralists to treat internal parasites in their livestock. This study aimed to determine the antibacterial and antioxidant potential of A. anthelmintica on pathogenic veterinary isolates. One hundred percent (100%) hexane (He100), 100% chloroform (Ch100), 100% ethanol (E100) and 70% ethanol (E70)...

Author(s):Kabo Wale, Tebogo Elvis Kwape, Laurah Sethibe, Goabaone Gaobotse, Daniel Loeto and Bongani

Article in Press

Antioxidant and antiproliferative activities of ethanolic extracts of Elateriospermum tapos Blume

Phytochemicals possessing free radical scavenging and antiproliferative activities play an important role in cancer chemoprevention. In this study, the ethanolic extracts prepared from fresh and dried leaves, bark, and seed skin of Pra (Elateriospermum tapos Blume.) were tested for their antioxidant activity using a FRAP assay. The antiproliferative activities against four human cancer cell lines, breast (MCF-7), colon...

Author(s):THANASET SENAWONG, PRASAN SWATSITANG, AUAMPORN RATTANASING, SITA TISADONDILOK

Article in Press

Utilization, Cultivation Practice and Economic Role of Medicinal Plants in Debre Markos Town, East Gojjam Zone, Amhara Region, Ethiopia

Medicinal plants are plants that are useful for primary health care and as remedy for diseases and injury, and plants used traditionally for foods and drinks and which are believed to be good for health. Despite the wide role of medicinal-plant, traditional utilization and management practices are not well documented specifically in Debremarkos town. Thus, this study was conducted to assess utilization and cultivation...

Author(s):YEBIRZAF YESHIWAS MELESE, Esubalew Tadele Agidew

Article in Press

In vivo efficacy of Dialium guineense Fruit Pulp on Hemeoxygenase-1 and Angiotensin Converting Enzyme in experimental Diabetes

The study was aimed at investigating the effect of aqueous fruit pulp of Dialium guineense on hemeoxygenase, and insulin release, inhibition of angiotensin converting enzyme (ACE) and possible hypoglycemia in streptozotocin-induced diabetic rats. Twenty four male Wistar rats were grouped into control, diabetic (Dm), diabetic + 300 mg/kg body weight Dialium guineese (Dm+ DG) and diabetic + 100 mg/kg metformin (Dm +MET)....

Author(s):ETAH ETAH NKANU, GABRIEL UJONG OTU, VICTORIA OKON EDEM and ESTHER IDIYAKKE GEORGE

Article in Press

Evaluation of Herbal Cocktail Used In the Treatment of Malaria on Liver Tissue of the Adult Wistar Rat

Interest is renewed in herbal medicine due to less side effects and belief of being safer. In addition there has been continued demand to obtain more drugs from plant sources to alleviate various ailments of mankind. This study is aimed at investigating the antimalarial activity of a herbal cocktail and individual plant extracts contained therein on Plasmodium berghei infected Wistar rats.Thirty five Wistar rats randomly...

Author(s):Anwara

Article in Press

Sub-chronic toxicity studies on the methanol stem bark extract of Uapaca togoensis (pax) in adult Wistar Rats

The stem bark and leaves of Uapaca togoensis has been used in traditional medicine to treat fever, epilepsy, rheumatism, vomiting and fatigue. The present study was designed to evaluate the acute and sub-chronic toxicity profile of the methanol stem bark extract of Uapaca togoensis as there are no reported toxicological studies on the plant. Preliminary phytochemical screening revealed the presence of alkaloids, steroids,...

Author(s):AMINA BUSOLA OLORUKOOBA, BEN AHMED CHINDO and JANE I EJIOFOR

Article in Press

In vitro antibacterial activity and antidiarraheic activity of root barks extracts of anogeissus leiocarpa (combretaceae) during an experimental bacterial diarrhea induced by escherichia coli esbl in albinos wistar rats

The present study was carried out to investigate in vitro and in vivo antibacterial activity of the root bark extracts of Anogeissus leiocarpa (DC) Guill. & Perr, in E. coli ESBL-induced diarrhea in rat. The antibacterial activity was performed in vitro by determining the inhibition zone using standard agar diffusion method as well as in vivo on E. coli infected Wistar rat model. Both minimum inhibitory concentration...

Author(s):Mani Adrien Kouangbe, Kouadio Henri Guillaume Sonan, Mouleymane Méité, Gogo Lucien BOGA, and Jean David N’Guessan

Article in Press

Quantification of bioactive compounds in Leucas biflora through high performance liquid chromatography

L. biflora (Vahl) R. Br. is ethnobotanically considered as cancer plant. It is arare medicinal plant. It is applied for the treatment of conjunctivitis, nasal bleeding, white discharge etc. For the medicinal property identification and quantitation of the bioactive compounds in this plant not been reported previously. Therefore, high performance liquid chromatography fingerprinting profile has been reported till date....

Author(s):Pal

Article in Press

Ethno-Botanical Study on the use and knowledge of medicinal plants at three kebeles of Fedis district of Oromiya regional state; adjacent to the Babile Elephant Sanctuary, Eastern Ethiopia.

This study was carried out to collect and document indigenous knowledge on medicinal plants among the traditional healers of Fedis district of Oromiya regional state, East Ethiopia. The ethnobotanical data were collected from 36 traditional healers (24 male and 12 female) using semi-structured questionnaire, observation and guided field walks. The survey identified 64 medicinal plants distributed into 39 families and 59...

Author(s):AMBERBIR ABEBE

Article in Press

Determination of the total phenolic content and spectral study of the herbal drug, Chromolona odorata Linn by spectrophotometric method

Chromolaena odorata is a medicinal plant that is widely used in folk medicine many Nigerian communities for treatment of several ailments and diseases. In particular, local formulations of the herbal plant are used to treat wounds, burns and skin infections. The plant extracts have also shown anticancer, antidiabetic, hepaprotective, anti-inflammatory, antimicrobial and antioxidant properties. The aim of the study was to...

Author(s):Nworie

Article in Press

Evaluation of the wound healing properties of methanolic bark extract of Samadera indica Gaertner in vivo

In the present study, bark samples of Samadera indica were collected, allowed to shade dry for a week, then coarsely powdered and was extracted with methanol by soxhlation process. The extract was used for wound healing experiment. In the wound healing study using excision wound model, 18 healthy Albino rats of four each with average body weight of 150-200 g was selected randomly for the study, which will be divided into...

Author(s):Rama Bhat, P.

Article in Press

A Review on the Phytochemical contents, medicinal uses and antimicrobial activities of Warburgia ugandensis

Warburgia ugandensis Sprague (Family Canellaceae); commonly known as Ugandan greenheart or pepper bark tree, is a highly valued medicinal plant in traditional medicine with a broad spectrum of antimicrobial activity whose parts especially the leaves and stem bark have for long been used in the treatment and management of many diseases and health conditions such as stomachache, cough, toothache, fever, malaria, oral thrush,...

Author(s):

Article in Press

Selenium-enriched polysaccharides from Pyracantha fortuneana (Se-PFPs) augment docetaxel-induced tumor suppression in human ovarian cancer

Background: Pyracantha fortuneana (Maxim.)(P. fortuneana) is a natural plant containing many healthy ingredients, including selenium-enriched polysaccharides. Selenium-enriched polysaccharides from Pyracantha fortuneana (Se-PFPs) have been proved to have antimutation and anti-oxidation activities. For instance, our previous research also found that Se-PFPs displayed anti-tumor activity in both ovarian cancer and breast...

Author(s):

Article in Press

OPTIMIZATION OF EXTRACTION, CHEMICAL CHARACTERIZATION AND ANTIMICROBIAL ACTIVITY OF ESSENTIAL OIL FROM BLACK CUMIN ( NIGELLA SATIVA L.) SEEDS BY USING CLEVENGER DISTILLATION

Essential oils are secondary metabolities that are highly concentrated substances extracted from flowers, leaves, stems, roots, seeds, barks, resins, or fruit rinds. Essential oils have been recognized as some of the most promising compounds in the development of novel products particularly in the pharmaceutical, agricultural, food and perfumery industries. Black cumin (Nigella sativa L.) belonging to family Rannunculaceae...

Author(s):Demis

Article in Press

Antifungal efficacy of crude extracts of Azadirachta indica and Vernonia amygdalina against Pathogenic Aspergillus niger (ATCC 16404)

This research work was conducted to assess the potency of ethanolic and hot water extract of Azadirachta indica and Vernonia amygdalina against pathogenic Aspergillus niger (ATCC 16404). Potato Dextrose Agar was the medium under which the antimicrobial sensitivity test was carried out. Streptomycin solution was also added to the medium to selectively inhibit the growth of bacterial cell. The results showed that, higher...

Author(s):Ninkuu, V, Adetunde, L.A, Sackey I and Diedong P

Article in Press

Evaluation of the phytochemical composition, antimicrobial and anti-radical activities of Mitracarpus scaber, (Rubiaceae)

Mitracarpus scaber is a medicinal plant used in traditional practices for the treatment of dermatoses and liver diseases. The objective of this study was to quantify the content of phenolic compounds and to evaluate the anti-radical and antimicrobial activities of four types of its total extracts on ten microbial strains. The Folin-Ciocalteu method was used to determine total phenol content, condensed tannin content by the...

Author(s):OUADJA B., ANANI K., DJERI B.., AMEYAPOH Y, KAROU D..S.

Article in Press

Ethnobotanical study on medicinal plants used by indigenous people in Tenta District, South Wollo, Ethiopia

Ethnobotanical study on medicinal plants was conducted in Tenta District, South Wollo, Ethiopia from December 2016 to May 2017. Data were collected using guided field walk, semi-structured interview, group discussion and direct field observation. Data were analysed using descriptive statistics and response compared with chi-square test. The results documented 121 species of medicinal plants under 98 genera and 53 families...

Author(s):Tibebu Tefera and Mesele Yihune

Article in Press

An Evaluation of the antioxidant and antimicrobial activities of Allium ampeloprasum var Iranicum, Echinophora platyloba L and Pistacia atlantica kurdica

The main aims of this study have been finding out the antioxidant and antimicrobial activities and preliminary phytochemical screening of three traditional plants of Iran namely, Allium ampeloprasum var. iranicum, Echinophora platyloba L and Pistacia atlantica kurdica were studied. In this experimental study, the maceration technique was used to prepare alcoholic extract. The effect of extract was analyzed based on disk...

Author(s):Avin Aghemiri, Asrin Aghemiri and Alireza Massiha

Article in Press

Ethnomedicinal importance of Gandrayan (Angelica glauca Edgew.) in the North-Western Indian Himalayan Region

Gandrayan (Angelica glauca Edgew., Family Apiaceae) is a high value medicinal herb and it is native and endemic to the Indian Himalayan Region. Its aromatic roots are used as spice and beside this the industrial demand of its essential oil is increasing for modern herbal medicines and aromatherapy. The present study was carried out to document its ethno-medicinal importance among local inhabitants of three Indian Himalayan...

Author(s):J. S. Butola, R. K. Vashistha, C. P. Kuniyal, A. R. Malik, S. S. Koranga and M. S. Rawat

Article in Press

Antibacterial and antioxidant activities of different cultivars of Zingiber officinale Roscoe grown in Sikkim Himalaya

Antimicrobial and antioxidant properties of different solvent extracts of five cultivars of Zingiber officinale were investigated. Out of the test organisms, Staphylococcus aureus was found most susceptible to chloroform extract of majhauley cultivar (26±0.1mm), while there was no activity recorded against Escherichia coli. The highest total phenol and flavonoid contents were recorded in the chloroform extract of...

Author(s):Sushen Pradhan, Arvind Kumar Goyal , Shiva Kumar Sharma and Pratap J. Handique

Article in Press

An investigation on environmental factors affecting the distribution of medicinal plants in North East Iran

The objective of this research was to investigate the effect of environmental factors on distribution of medicinal plants in Chaharbagh rangelands in North East Iran. Sampling of vegetation was performed in quadrats positioned in the study area using a randomized-systematic method. Vegetation data including medicinal plants and their density were estimated quantitatively within each quadrat. The topographic conditions...

Author(s):Behmanesh, B , Heshmati, G. A. and Mahiny, A. S.

Article in Press

Chemical composition and phytotoxcity of Juniperus phoenicea needles

Leachate (100, 200, 300, 400 and 500 g/l), aqueous (10, 20, 30 and 40 g/l) and organic (petroleum ether, chloroform and acetone, at 2000, 4000 and 6000 ppm) extracts of Juniperus phoenicea needles were tested on radish, lettuce, barley and tomato, to evaluate their phytotoxicity. Pot cultures were conducted by incorporation needles powder (50 and 100 g/kg) in soil and by irrigation with their leachate and aqueous...

Author(s):Kmar M'barek, and Rabiaa Haouala

Article in Press

Antimicrobial potential of parasitic plant Cuscuta reflexa with Nerium oleander host plant successive extract against selected test microbes

Cuscuta reflexa is a parasitic plant having many medicinal properties and used as traditional medicine in Ayurveda for the treatment of various disorders. In the present research work, researchers have investigated antimicrobial ability of C. reflexa with Nerium oleander host plant successive extracts against selected human pathogenic bacteria. Escherichia coli (MTCC 730), Proteus vulgaris (MTCC 1771), Staphylococcus...

Author(s):Pooja Saini , Ekta Menghani and Rekha Mithal

Article in Press

Evaluation of the aqueous and methanolic fresh leaf extracts of Cnidoscolous aconitifolius for anxiolytic activity

Cnidoscolous aconitifolius promotes anxiolysis in humans. Fresh leaf extracts are claimed to possess greater anxiolytic activity as compared to dry leaf extracts. This study investigated the anxiety alleviating activity of two fresh leaf extracts {aqueous fresh leaf extract (AFLE) and methanolic fresh leaf extract (MFLE)} and a dry leaf extract {methanolic dry leaf extract (MFLE)} of C. acontifolius. Swiss albino mice...

Author(s):Adebiyi O. A. , Adebiyi O. O. and Adu T. S.

Article in Press

Antioxidant, DNA protective and antibacterial activities of Terminalia bellerica extracts

Terminalia bellerica Roxb., commonly known as Beleric myrobalan, is a well-known large deciduous tree with various pharmaceutical properties. However, scientific information on T. bellerica, growing in India, as regards to its phytochemical constituents and pharmacological properties is very limited. With this in view, this study investigated the antioxidant, DNA protective and antibacterial activities of different parts...

Author(s):Rasna Gupta and Ram Lakhan Singh

Article in Press

Effect of aqueous leaf extracts of Leptadenia hastata Pers (Decne) on spermiogram and testicular histology in albino rats (Wistar strain)

This study was designed to determine the effects of prolonged oral administration of aqueous leaf extract of Leptadenia hastata Pers (Decne) on sperm concentration, sperm motility and testicular histology in Wistar rats. Rats were given graded doses (200, 400, 600 and 800 mg kg-1) of aqueous leaf extract of L. hastata orally for 28 days. Weekly changes in sperm concentration and motility as well as testicular weight and...

Author(s):Victoria Adam Maina, Innocent Damudu Peter, Dauda Yahi, Umar Kyari Sandabe and Godwin Onyeamaechi Egwu

Article in Press

Isolation, characterization and biological activity of organic extractives from Calodendrum capense (L.f.) Thunb.(Rutaceae)

A novel prenylfuroquinoline alkaloid capensenin (1), an alkaloid confusameline (2), two furanocoumarins psolaren (3) and bergapten (4), were isolated from hexane and dichloromethane crude extracts of stem bark, leaves and fruit pericarp of Calodendrum capense. Limonin (5) was also isolated from the stem bark, while limonin diosphenol (6) was isolated from the seeds. Capensenin (1) showed weak antimicrobial activity against...

Author(s):Okwemba R. I., Tarus P. K., Machocho A. K., Wanyonyi A. W., Waweru, I. M., Onyancha J. M., Onani M. O. and Amuka O.

Article in Press

Comparative quantification of Baicalein and heavy metal in various aerial parts of Oroxylum indicum (L.) Kurz from Jharkhand and Uttrakhand states of India

Oroxylum indicum (L.) Kurz (Shyonak, Indian trumpet tree, Midnight horror) belongs to the family Bignoniaceae and has been used as a single drug or as a component of certain poly-herbal drug preparations in Indian Ayurvedic system of medicine. Oroxylum indicum is reported to contain flavonoids, namely, chrysin, oroxylin-A, scutellarin, and baicalein. Baicalein is reported to have anti-cancerous activity and inhibits...

Author(s):Swati Sinha, Tapan K Nailwal and Anupam Pandey

Article in Press

Pharmaceutical topical gel containing proanthocyanidin polymers-rich fraction from Stryphnodendron adstringens

The stem bark of Stryphnodendron adstringens, popularly known in Brazil as "barbatimão", has many biological activities, including antifungal activity. Considering the increasing interest of using "barbatimão" extract in the treatment of vaginal candidiasis, the aim of this study was to propose a pharmaceutical topical gel containing a proanthocyanidin polymers-rich fraction for use as a pharmacological agent in vaginal...

Author(s):Marco Antonio Costa, Andressa Blainski, Vanessa Kaplum, Marli Miriam de Souza Lima, Tânia Ueda-Nakamura, Benedito Prado Dias Filho, João Carlos Palazzo de Mello and Celso Vataru Nakamura

Article in Press

In vitro antiviral activity of Brazilian Cerrado plant extracts against animal and human herpesviruses

The Brazilian savanna known as “Cerrado” is very rich in medicinal plants that are used by the local population for treatment of several illnesses. The herpesvirus is a serious problem worldwide, and affects both animal and human health. This work aimed to study the antiviral activity of eight extracts from plants natives of “Cerrado” region against human (HSV-1), equine (EqHV-1) and swine herpesviruses (SuHV-1). The...

Author(s):Marina A. Padilla, Isabela C. Simoni, Verônica Moreira H. Hoe, Maria J. Bittencourt Fernandes, Clarice W. Arns, Juliana R. Brito and João Henrique G. Lago

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