Journal of
Medicinal Plants Research

  • Abbreviation: J. Med. Plants Res.
  • Language: English
  • ISSN: 1996-0875
  • DOI: 10.5897/JMPR
  • Start Year: 2007

JMPR Articles in press

Article in Press

Hypoglycemic activity of Antidesma bunius (L.) Spreng and Mollugo oppositifolia L. fresh and alcoholic extracts in the db/db diabetic mouse model

Antidesma bunius (L.) Spreng and Mollugo oppositifolia L., also known as “bignay” and “malagoso,” respectively, are commonly used medicinal plants in the Philippines to treat diabetes. However, the hypoglycemic effect of Antidesma bunius (L.) Spreng and Mollugo oppositifolia L. has not been reported to date. Therefore, this study was undertaken to investigate the hypoglycemic effects of the fresh and ethanolic extracts of...

Author(s):N. C. Tanquilut, N. Q. Alonzo, A. E. Jamesd D. K. Rowlands, G. C. Sanchez, R. D. San Jose , E. Yesner, M. R. C. Tanquilut, B. A. S. Reyes

Article in Press

Chromatography and Bioautography of endophytic fungi extracts of Uncaria tomentosa (Willd.) DC with antibacterial activity

Endophytic fungi of different species have already proved their efficacy against a range of pathogenic bacteria. However, the separation of the compounds contained in these extracts that actually have an effective activity is not a constant, but it is essential for the scientific knowledge to formulate a new medication. Thus, this study aimed to separate compounds from two endophytic fungi extracts of Uncaria tomentosa...

Author(s):Fernando Generoso da Silva GONÇALVES; Jonatas Conceição de ARAÚJO; Dionízio da Silva BRASIL; Rodrigo Asfury RODRIGUES; Clarice Maia CARVALHO

Article in Press

DNA methylation as the most important content of epigenetics in traditional Chinese herbal medicine

Traditional Chinese medicine is commonly used in China and so many other Asian and western Countries. Epigenetics relates to heritable alternations in chromatin architecture that do not involve changes in the underlying DNA sequence but profoundly affect gene expression and impact cellular function. Epigenetic regulation is attained by specific mechanisms involving DNA methylation, histone posttranslational modifications...

Author(s):Mohamad Hesam Shahrajabian, Wenli Sun, Qi Cheng

Article in Press

Evaluation of aphrodisiac properties of the aqueous extract of the trunk barks of Spathodea campanulata P. Beauv. (Bignoniaceae) on albino rats (Rattus norvegicus)

Spathodea campanulata P.Beauvois (Bignoniaceae) is a tree from the tropical and subtropical forests of Africa, used in folk medicine for the treatment of several diseases such as gastric pain, rheumatism, lumbago, cataracts and some intestinal parasites. In West Cameroon, traditional healers use a decoction of the bark of the trunk as an aphrodisiac in males. The objective of the present study was to evaluate the...

Author(s):Talla Clovis, Ilyassa Yaya, Nnanga Nga, Dibong Siegfried Didier, Mpondo Mpondo Emmanuel

Article in Press

Chemical composition, in vitro antioxidant and antiparasitic properties of the essential oils of three plants used in traditional medicine in Benin.

Sclerocarya birrea (Sb), Psidium guajava (Pg) and Eucalyptus camaldulensis (Ec) are widely used in traditional medicine for the treatment of many diseases, some of which were related to oxidative stress and parasitic diseases. Our work aims to evaluate the in vitro antioxidant and antiparasitic activities of the essential oils of Sb, Pg and Ec from Benin, as well as their cytotoxicity. The essential oils of Sb, Pg and Ec...

Author(s):Didier Kpadonou, Salomé Kpoviessi, Joanne Bero, Pierre Agbani, Fernand Gbaguidi, Bénédict Kpadonou-Kpoviessi, Brice Sinsin, Michel Frédérich, Joëlle Quetin-Leclercq

Article in Press

An investigation into the practice and perceived essence of medicinal herb authentication by some stakeholders of traditional medicine in Ogbomoso, Oyo state, Nigeria

Reports from extensive surveys have indicated that about 70-80% of the world population; particularly in the developing countries rely on non-conventional medicine mainly of herbal origins for their primary health care. Correct identification and quality assurance of the starting materials are essential prerequisites to ensuring reproducible quality of herbal medicine which will contribute to its safety and efficacy. This...

Author(s):Adepoju Tunde Joseph OGUNKUNLE, Jennifer Ejiro IDEH, Esther Olubukola OBIREMI and Muhammed Adekunle JIMOH

Article in Press

Phytochemical Screening and in vitro Evaluation of Antibacterial Activity of aqueous and Ethanolic extracts of root and stem Bark of Bridelia ferruginea. Benth.[Euphorbiaceae]

This study aimed at analysing the phytochemical content and antimicrobial activity of Bridelia ferrugine aagainst selected bacteria. Methods: Total saponin, alkaloids, tannins, flavonoids and total anthraquinone contents were evaluated using spectrophotometric equivalents of the standards. The antibacterial activity of the plant extracts weredetermined usingMinimum Inhibitory Concentration (MIC) and Minimum Bactericidal...

Author(s):Mela Ilu Leka, Stanley Chukwudozie Onuoha, Vincent Olasoji Oladele, John Aguiyi

Article in Press

Bioactive Compounds and Antioxidant Properties of Different Plant Parts of Andrographis paniculata (Burm. F.) Nees at Young and Mature Development Stage

Plant part such asleaves, stems, branches, twigs, and roots possess different therapeutic functions and activities. Besides that, development stages, either young or mature could cause several effects to the bioactive compounds as well as the antioxidant properties of the plant. Thus, an experiment was conducted using a nested design, with three replications, involved young and mature development stages and three different...

Author(s):Nor Elliza Tajidin, Mahmud Tengku Muda Mohamed, Nor Shariah Salleh, Munirah Mohamad, Bunga Raya Ketaren

Article in Press

Ethno-botanical studies of plants used for the treatment of malaria by some herbalists of the Ghana Federation of Traditional and Alternative Medicine (GHAFTRAM).

The use of medicinal plants for the treatment of diseases including malaria is common in Ghanaian traditional medicine. The objective of this study is to document indigenous knowledge of medicinal plants used for the treatment of malaria through ethno-botanical studies to facilitate the discovery of new sources of drugs. The study was carried out in 2018 at the Centre for Plant Medicine Research (CPMR) among 36 registered...

Author(s):Tonny Asafo-Agyei, Heron R. Blagogee, Susana Oteng Mintah, Mary-Ann Archer, Frederick Ayertey, Alexis Conrad Sapaty, Peter Atta-Adjei Jnr, Daniel Boamah, Jerry Asiedu-Larbi, Alfred Ampomah Appiah

Article in Press

Larvicide and repellent activity of hypenia irregularis (benth.) harley in the alternative control of mosquito Aedes aegypti

Dengue is an emerging epidemic disease that among those transmitted by the Aedes aegypti mosquito is the one with the highest number of cases and cases with death. With the wide dissemination of the beneficial effects of medicinal plants and the use in agriculture as a pesticide, studies on the prospection of plants with toxic activity have been increasing, highlighting extracts and essential oils. The objective of this...

Author(s):Richard Dias Possel, Talita Pereira de Souza Ferreira, Diego Patrick Nusrala Dias, Patrícia Verdugo Pascoal, Giovanna Cardoso Amui, Taciano Peres Ferreira, Ana Claudia Fernandes, Raimundo Wagner de Souza Aguiar

Article in Press

Antimicrobial activity and acetilcolinesterase inhibition of oils and amazon fruit extracts

The present work consists on the evaluation of antimicrobial activity and inhibition of the enzyme acetylcholinesterase (AChE) of fixed oils and hexane extracts of nine fruits with the following native names: abiu (Pouteria caimito), acerola (Malpighia emarginata), araçá (Psidium cattleianum), bacuparí (Rheedia gardneriana), biribá (Rollinia mucosa), camu-camu (Myrciaria dubia), fruta-do-conde (Annona squamosa), graviola...

Author(s):Ismael Montero Fernandez, Selvin Antonio Maldonado

Article in Press

ETHNOMEDICINAL EVALUATION OF SOME ANTIMALARIAL PLANTS USED IN ONDO STATE, NIGERIA

The use of herbs and plant materials have always been popular in the treatment of febrile illness, and it has grown over time in malaria endemic areas. Structured questionnaires were administered in four towns in each of the three senatorial districts of Ondo state to know the most commonly used herbs and the results suggested Mango (Mangifera indica) Siam weed (Chromolaena odorata) and Guava (Psidium guajava) as most...

Author(s):IYABO ADEPEJU SIMON-OKE

Article in Press

Alcoholic Extracts from Alchornea cordifolia (Schumach. & Thonn.) Mull. Arg. improved survival of Drosophila melanogaster infected with virulent Aspergillus spp

Antifungal activity of the ethanolic extract of Alchornea cordifolia plant was evaluated both in vitro and in vivo against Aspergillus fumigatus, and Aspergillus terreus, mostly implicated in plant and animal fungal diseases. Antifungal potential of the extract were evaluated quantitatively in vitro using well diffusion method and in vivo by studying the survival rate of Drosophila melanogaster (Harwich) challenged with...

Author(s):Wuyep Ponchang

Article in Press

Preparation and Pharmaceutical Evaluation of Cream Containing Bioactive Peptides Derived from Soybean

Hyper pigmentation is skin disorders affect the color of skin that may require treatment. There are many chemical agents to treatment of hyper pigmentation such as hydroquinone, retinoids and other agents but do not satisfactory results and may be highly morbid. In addition to consumer prospective natural origin is more acceptable with mush less contraindication. Soybean derived peptides have demonstrated numerous...

Author(s):SHATALEBI MOHAMMADALI

Article in Press

Blood Glucose Lowering, Antioxidant and Nutritional Characteristics of Raw and Fermented African Star Apple Seeds (Chrysophyllum africanum) Flour.

Plant-based foods have health benefits and minimal side effects than synthetic anti-diabetic agents. Therefore, this study evaluated nutritional and anti-hyperglycaemic efficacies of raw African star apple (RASA) and fermented African star apple seeds (FASA). Methodology: The RASA and FASA seeds were processed into flour, and nutritional qualities, antioxidative and antidiabetic activities in wistar rats were evaluated at...

Author(s):Oluwole Steve IJAROTIMI

Article in Press

ANALGESIC AND ANTI-INFLAMMATORY PROPERTIES OF AQUEOUS EXTRACT FROM THE STEM BARK OF Piptadeniastrum Africanum (MIMOSACEAE) IN MICE AND RATS

The stem bark of Piptadeniastrum africanum (Hook. F.) (syn. Piptadenia Africana) Brenan (Mimosaceae) is used in Cameroonian and Gabonese folk medicine for the relief of some painful sicknesses. This study was intended to evaluate the analgesic and anti-inflammatory activities of the aqueous extract of P. africanum. The analgesic investigations were carried out against acute noxious stimuli, that are chemical (acetic...

Author(s):MARIUS MBIANTCHA

Article in Press

Ethno Botanical Perspective of Medicinal Plants in Mulkhow Valley District Upper Chitral, Pakistan

This paper demonstrates the ethnobotanical perspectives of medicinal plant in Mulkhow valley, district Chitral. The main aim of this research work was to gather information to document the medicinal uses of plants in Mulkhow valley. The results of ethnobotanical perspective contain quantitative information of medicinal plants used by indigenous people in Mulkhow valley. The current study conducted between 2015 – 2016...

Author(s):ZAHOOR UL HAQ

Article in Press

Dominant lethal mutations in rats fed on the seed extract of Mucuna urens

Dominant lethal mutation assay (DLMA) was carried out on rats after being treated with graded doses of ethanol extract of the seeds of Mucuna urens. Male albino rats(Wister strain) were caged in four groups labeled, group I, group II, group III and group IV and treated with graded dosages of the ethanol extract of the seeds of M. urens ; 70mg/kg BW, 140mg/kg BW and 210mg/kg BW, respectively, for 14 days. The positive...

Author(s):Hannah Edim Etta

Article in Press

Ethnobotanical Study of Selected Medicinal Plants used against Bacterial infections in Nandi conty, Kenya

Globally, medicinal plants have been used to treat different human ailments from time immemorial. In Kenya, various plants are used by local people in the treatment of various diseases.This is a common practice in Nandi county due to scarce health facilities in the region, traditional beliefs, cultural barriers and availability of medicinal plants. The objective of this study was to carry out an ethnobotanical survey to...

Author(s):Philip A. Ogutu, Charles Mutai

Article in Press

Assessment of Total Content of Secondary Metabolites, In Vitro Free Radical Scavenging Potential and peroxide value on Different Solvent Extracts of Rumex abyssinicus Jacq. Root

Medicinal plants have bioactive compounds which are used for curing of various human diseases and also play an important role in healing. Phytochemicals have two categories. These are primary and secondary constituents. Primary constituents have chlorophyll, proteins sugar and amino acids. Secondary constituents contains like terpenoids, flavonoids, saponins, tannins, alkaloids, glycosides and phenols. Secondary...

Author(s):Limenew Abate

Article in Press

Phenolic Profile from The Leaves Extracts of Annona Muricata L: Their Effect Antioxidant and Antiviral

Soursop (Annona muricata L.) is a perennial tree whose leaves have been used in traditional medicine. To assess the biological properties of Annona muricata L leaves characterizing phenolic compounds by Ultra Performance Liquid Chromatography (UPLC), evaluating their antioxidant effects on human erythrocytes and antiviral effectiveness by using enteric virus surrogates. The phenolics compounds were estimated using UPLC...

Author(s):SILVA BELTRÁN NORMA PATRICIA, BALDERRAMA CARMONA ANA PAOLA, RUÍZ CRUZ SAÚL, CHAIDEZ QUIROZ CRISTÓBAL, LÓPEZ MATA MARCO ANTONIO, NÚÑEZ GASTELÚM JOSÉ A

Article in Press

Antibacterial and Antioxidant Compounds from the Tubers Extracts of Plectranthus edulis

P. edulis is an indigenous plant which has been cultivated for its edible tuber. It is claimed to have antibacterial activity. But this was not supported by scientific investigation. Hence this work explores the antibacterial and antioxidant activities of extracts and isolated compounds from the tuber of P. edulis. The effects of the extracts and isolated compounds of tubers of P. edulis were evaluated against S. aureus,...

Author(s):Yadessa Melaku, Tolessa Duguma

Article in Press

Ethno botanical study of medicinal plants used to treat human disease in and around Ambo town, Western Ethiopia a

Ethiopia has numerous plants that can be used as sources of medicine for those who cannot access modern health care. This study was conducted to document the indigenous knowledge and medicinal plants in and around Ambo town. The study was carried out from April to August 2018. A total of 49 participants were selected randomly from the representative kebeles. Twenty two medicinal plants were collected and documented based...

Author(s):Tilahun Tolossa, Adelegn Bogale

Article in Press

Antibacterial, cytotoxic and antioxidant activities of Boscia Senegalensis and Tapinanthus dodoneifolius

Boscia senegalensis and Tapinanthus dodoneifolius are two plants mostly used by herders to treat animal diseases in the Far North Region of Cameroon. To evaluate the in vitro antibacterial, cytotoxic and antioxidant potentials of these plants. To achieve this, five extracts (water, methanol, chloroform and hexane) of both plants obtained by successive fractionation were used. Antibacterial activities of the different...

Author(s):Ronald Romuald B. Vougat Ngom, Ziebe Roland, Rebecca B. Garabed, Foyet Harquin Simplice

Article in Press

ETHNO-MEDICINAL STUDY OF PLANTS USED FOR TREATMENT OF HUMAN AND LIVESTOCK AILMENTS BY TRADITIONAL HEALERS IN GOBA WOREDA, BALE ZONE, OROMIA, ETHIOPIA

ABSTRACT The investigation of traditional medicinal plants was performed in Bale district from August to October 2018 in three kebeles Kedu, Elasa and Aloshe Tilo. In the study area diverse medicinal plant were used to treat many human and livestock disease. The data were collected from the informants through semi-structured interview, discussion and collected plant samples from the study areas that were used to treat...

Author(s):HABTAMU TEDILA MENGISTU

Article in Press

Acute and Sub-acute toxicity studies of the ethanolic stem and root extract of Aristolochia ringens (vahl) and Securidaca longepedunculata fresens in rats.

Aristolochia ringens (Vahl) and Securidaca longepedunculata Fresens are used in traditional African medicine for the treatment of arthritis, diarrhoea, asthma, snakebites and skin rashes. This present study examines the acute and sub-acute toxicity effects of these plants in rats. The animals (5 per group) were treated daily with the extract at doses of 100, 250, 500 mg/kg orally for 28 days. Control group received...

Author(s):Adedotun Adekunle and Adewale Lawal

Article in Press

Large cardamom (A. subulatum Roxb) is perhaps among the oldest spices to be known for mankind which is one livelihood option for mountain inhabitants

Large cardamom (Amomum. subulatum Roxb) commonly known as a badi elaichi, is a tall, perennial, evergreen, herbaceous monocot plant. Large cardamom is well known spice, which has medicinal value. The present study has been designed to explore the base line morphological characteristics, chemo-profile, to raise superior quality planting materials through micro propagation and large cardamom farming as an appropriate...

Author(s): ARVIND K BHANDARI

Article in Press

An Ethnobotanical Study of Traditionally Used Medicinal Plants for Treatment of Human Diseases in Goba District of Bale Zone, Southeast Ethiopia

An ethnobotanical study of traditionally used medicinal plants to trat human disease was conducted in Goba District of Bale Zone, Ethiopia. Information was gathered from 60 informants using semi-structured interview. For data collection the site and the informants were selected purposivelly. During the study, a total of 42 medicinal plant speceis belonging to 24 families were recorded. The family Euphorbiaceae has four...

Author(s):SEBSIBE AYALEW

Article in Press

Effect of dosage of methanol and omidun extracts of root of V. paradoxa on hematological parameters of diarrhea-induced Albino rats

Investigation was carried out on the effects of 50mg/mL and 100mg/mL concentration of methanol and omidun extracts of root of V. paradoxa on hematological parameters of diarrhea induced albino rats. A total of 5 test organisms ((Shigella dysenteriae, Salmonella typhi, Escherichia coli ATCC 25922,Enteropathogenic Escherichia coli ‘EPEC ATCC 43887’, Enterohemorrhagic Escherichia coli ‘EHEC ATCC 43889’) associated with...

Author(s):Falana M. B

Article in Press

Effects of aqueous mango leaf (Magnifera indica) on alloxan-induced diabetes in albino rats “Rattus rattus”

Studies on the medicinal (hypoglycemic) potential of Magnifera indica (M. indica) have been documented. However, little may still be known about the dose level and the effects it may have on haematocrit, liver enzymes and body weight of a diabetic individual. The present study was designed to investigate the hypoglycemic effect of aqueous M. indica leaves extract on alloxan-induced diabetes in albino rats Rattus rattus....

Author(s):Andong

Article in Press

The Effect of Chloroform Extract of Chasmenthera dependens Roots on some Liver marker enzymes on Carbon Tetrachloride (Ccl4) Induced Hepatotoxicity in Wistar Albino Rats.

This study evaluated the phytoconstituents of the chloroform extract of Chasmenthera dependens (C. dependens) roots and the effect of the extract on the liver serum/homogenate enzyme activities of carbon Tetrachloride Induced hepatoxicity in Wistar Albino Rats. Twenty-four (24) female albino rats were used for this study and were divided into groups of four rats each: Groups I rats were normal control. Hepatotoxicity was...

Author(s):CHIOMA ASSUMPTA ANOSIKE, JUSTUS NMADUKA NWACHUKWU, CHINEDU SAMUEL OGBOZOR, CHIDI AUGUSTINE MADUEKEU

Article in Press

A Review of the Ethnomedicinal uses of pteridophytes for treating various human ailments in India

Pteridophytes present significant evolutionary innovations such as development of true conducting system with xylem and phloem and dominant saprophytic phase. Pteridophytes are frequently used as ornamental plants because of the green long lasting large foliage and sturdy plant forms. They are being used as bio-indicators for pollution, phytoremediators, and some used as bio-fertilizers. During the invasion of land...

Author(s):Uniyal

Article in Press

Sub-chronic toxicity studies on the methanol stem bark extract of Uapaca togoensis (pax) in adult Wistar Rats

The stem bark and leaves of Uapaca togoensis has been used in traditional medicine to treat fever, epilepsy, rheumatism, vomiting and fatigue. The present study was designed to evaluate the acute and sub-chronic toxicity profile of the methanol stem bark extract of Uapaca togoensis as there are no reported toxicological studies on the plant. Preliminary phytochemical screening revealed the presence of alkaloids, steroids,...

Author(s):AMINA BUSOLA OLORUKOOBA, BEN AHMED CHINDO and JANE I EJIOFOR

Article in Press

Quantification of bioactive compounds in Leucas biflora through high performance liquid chromatography

L. biflora (Vahl) R. Br. is ethnobotanically considered as cancer plant. It is arare medicinal plant. It is applied for the treatment of conjunctivitis, nasal bleeding, white discharge etc. For the medicinal property identification and quantitation of the bioactive compounds in this plant not been reported previously. Therefore, high performance liquid chromatography fingerprinting profile has been reported till date....

Author(s):Pal

Article in Press

Ethno-Botanical Study on the use and knowledge of medicinal plants at three kebeles of Fedis district of Oromiya regional state; adjacent to the Babile Elephant Sanctuary, Eastern Ethiopia.

This study was carried out to collect and document indigenous knowledge on medicinal plants among the traditional healers of Fedis district of Oromiya regional state, East Ethiopia. The ethnobotanical data were collected from 36 traditional healers (24 male and 12 female) using semi-structured questionnaire, observation and guided field walks. The survey identified 64 medicinal plants distributed into 39 families and 59...

Author(s):AMBERBIR ABEBE

Article in Press

Determination of the total phenolic content and spectral study of the herbal drug, Chromolona odorata Linn by spectrophotometric method

Chromolaena odorata is a medicinal plant that is widely used in folk medicine many Nigerian communities for treatment of several ailments and diseases. In particular, local formulations of the herbal plant are used to treat wounds, burns and skin infections. The plant extracts have also shown anticancer, antidiabetic, hepaprotective, anti-inflammatory, antimicrobial and antioxidant properties. The aim of the study was to...

Author(s):Nworie

Article in Press

Evaluation of the wound healing properties of methanolic bark extract of Samadera indica Gaertner in vivo

In the present study, bark samples of Samadera indica were collected, allowed to shade dry for a week, then coarsely powdered and was extracted with methanol by soxhlation process. The extract was used for wound healing experiment. In the wound healing study using excision wound model, 18 healthy Albino rats of four each with average body weight of 150-200 g was selected randomly for the study, which will be divided into...

Author(s):Rama Bhat, P.

Article in Press

OPTIMIZATION OF EXTRACTION, CHEMICAL CHARACTERIZATION AND ANTIMICROBIAL ACTIVITY OF ESSENTIAL OIL FROM BLACK CUMIN ( NIGELLA SATIVA L.) SEEDS BY USING CLEVENGER DISTILLATION

Essential oils are secondary metabolities that are highly concentrated substances extracted from flowers, leaves, stems, roots, seeds, barks, resins, or fruit rinds. Essential oils have been recognized as some of the most promising compounds in the development of novel products particularly in the pharmaceutical, agricultural, food and perfumery industries. Black cumin (Nigella sativa L.) belonging to family Rannunculaceae...

Author(s):Demis

Article in Press

Antifungal efficacy of crude extracts of Azadirachta indica and Vernonia amygdalina against Pathogenic Aspergillus niger (ATCC 16404)

This research work was conducted to assess the potency of ethanolic and hot water extract of Azadirachta indica and Vernonia amygdalina against pathogenic Aspergillus niger (ATCC 16404). Potato Dextrose Agar was the medium under which the antimicrobial sensitivity test was carried out. Streptomycin solution was also added to the medium to selectively inhibit the growth of bacterial cell. The results showed that, higher...

Author(s):Ninkuu, V, Adetunde, L.A, Sackey I and Diedong P

Article in Press

An Evaluation of the antioxidant and antimicrobial activities of Allium ampeloprasum var Iranicum, Echinophora platyloba L and Pistacia atlantica kurdica

The main aims of this study have been finding out the antioxidant and antimicrobial activities and preliminary phytochemical screening of three traditional plants of Iran namely, Allium ampeloprasum var. iranicum, Echinophora platyloba L and Pistacia atlantica kurdica were studied. In this experimental study, the maceration technique was used to prepare alcoholic extract. The effect of extract was analyzed based on disk...

Author(s):Avin Aghemiri, Asrin Aghemiri and Alireza Massiha

Article in Press

Ethnomedicinal importance of Gandrayan (Angelica glauca Edgew.) in the North-Western Indian Himalayan Region

Gandrayan (Angelica glauca Edgew., Family Apiaceae) is a high value medicinal herb and it is native and endemic to the Indian Himalayan Region. Its aromatic roots are used as spice and beside this the industrial demand of its essential oil is increasing for modern herbal medicines and aromatherapy. The present study was carried out to document its ethno-medicinal importance among local inhabitants of three Indian Himalayan...

Author(s):J. S. Butola, R. K. Vashistha, C. P. Kuniyal, A. R. Malik, S. S. Koranga and M. S. Rawat

Article in Press

Antibacterial and antioxidant activities of different cultivars of Zingiber officinale Roscoe grown in Sikkim Himalaya

Antimicrobial and antioxidant properties of different solvent extracts of five cultivars of Zingiber officinale were investigated. Out of the test organisms, Staphylococcus aureus was found most susceptible to chloroform extract of majhauley cultivar (26±0.1mm), while there was no activity recorded against Escherichia coli. The highest total phenol and flavonoid contents were recorded in the chloroform extract of...

Author(s):Sushen Pradhan, Arvind Kumar Goyal , Shiva Kumar Sharma and Pratap J. Handique

Article in Press

An investigation on environmental factors affecting the distribution of medicinal plants in North East Iran

The objective of this research was to investigate the effect of environmental factors on distribution of medicinal plants in Chaharbagh rangelands in North East Iran. Sampling of vegetation was performed in quadrats positioned in the study area using a randomized-systematic method. Vegetation data including medicinal plants and their density were estimated quantitatively within each quadrat. The topographic conditions...

Author(s):Behmanesh, B , Heshmati, G. A. and Mahiny, A. S.

Article in Press

Antimicrobial potential of parasitic plant Cuscuta reflexa with Nerium oleander host plant successive extract against selected test microbes

Cuscuta reflexa is a parasitic plant having many medicinal properties and used as traditional medicine in Ayurveda for the treatment of various disorders. In the present research work, researchers have investigated antimicrobial ability of C. reflexa with Nerium oleander host plant successive extracts against selected human pathogenic bacteria. Escherichia coli (MTCC 730), Proteus vulgaris (MTCC 1771), Staphylococcus...

Author(s):Pooja Saini , Ekta Menghani and Rekha Mithal

Article in Press

Evaluation of the aqueous and methanolic fresh leaf extracts of Cnidoscolous aconitifolius for anxiolytic activity

Cnidoscolous aconitifolius promotes anxiolysis in humans. Fresh leaf extracts are claimed to possess greater anxiolytic activity as compared to dry leaf extracts. This study investigated the anxiety alleviating activity of two fresh leaf extracts {aqueous fresh leaf extract (AFLE) and methanolic fresh leaf extract (MFLE)} and a dry leaf extract {methanolic dry leaf extract (MFLE)} of C. acontifolius. Swiss albino mice...

Author(s):Adebiyi O. A. , Adebiyi O. O. and Adu T. S.

Article in Press

Antioxidant, DNA protective and antibacterial activities of Terminalia bellerica extracts

Terminalia bellerica Roxb., commonly known as Beleric myrobalan, is a well-known large deciduous tree with various pharmaceutical properties. However, scientific information on T. bellerica, growing in India, as regards to its phytochemical constituents and pharmacological properties is very limited. With this in view, this study investigated the antioxidant, DNA protective and antibacterial activities of different parts...

Author(s):Rasna Gupta and Ram Lakhan Singh

Article in Press

Effect of aqueous leaf extracts of Leptadenia hastata Pers (Decne) on spermiogram and testicular histology in albino rats (Wistar strain)

This study was designed to determine the effects of prolonged oral administration of aqueous leaf extract of Leptadenia hastata Pers (Decne) on sperm concentration, sperm motility and testicular histology in Wistar rats. Rats were given graded doses (200, 400, 600 and 800 mg kg-1) of aqueous leaf extract of L. hastata orally for 28 days. Weekly changes in sperm concentration and motility as well as testicular weight and...

Author(s):Victoria Adam Maina, Innocent Damudu Peter, Dauda Yahi, Umar Kyari Sandabe and Godwin Onyeamaechi Egwu

Article in Press

Isolation, characterization and biological activity of organic extractives from Calodendrum capense (L.f.) Thunb.(Rutaceae)

A novel prenylfuroquinoline alkaloid capensenin (1), an alkaloid confusameline (2), two furanocoumarins psolaren (3) and bergapten (4), were isolated from hexane and dichloromethane crude extracts of stem bark, leaves and fruit pericarp of Calodendrum capense. Limonin (5) was also isolated from the stem bark, while limonin diosphenol (6) was isolated from the seeds. Capensenin (1) showed weak antimicrobial activity against...

Author(s):Okwemba R. I., Tarus P. K., Machocho A. K., Wanyonyi A. W., Waweru, I. M., Onyancha J. M., Onani M. O. and Amuka O.

Article in Press

Comparative quantification of Baicalein and heavy metal in various aerial parts of Oroxylum indicum (L.) Kurz from Jharkhand and Uttrakhand states of India

Oroxylum indicum (L.) Kurz (Shyonak, Indian trumpet tree, Midnight horror) belongs to the family Bignoniaceae and has been used as a single drug or as a component of certain poly-herbal drug preparations in Indian Ayurvedic system of medicine. Oroxylum indicum is reported to contain flavonoids, namely, chrysin, oroxylin-A, scutellarin, and baicalein. Baicalein is reported to have anti-cancerous activity and inhibits...

Author(s):Swati Sinha, Tapan K Nailwal and Anupam Pandey

Article in Press

Pharmaceutical topical gel containing proanthocyanidin polymers-rich fraction from Stryphnodendron adstringens

The stem bark of Stryphnodendron adstringens, popularly known in Brazil as "barbatimão", has many biological activities, including antifungal activity. Considering the increasing interest of using "barbatimão" extract in the treatment of vaginal candidiasis, the aim of this study was to propose a pharmaceutical topical gel containing a proanthocyanidin polymers-rich fraction for use as a pharmacological agent in vaginal...

Author(s):Marco Antonio Costa, Andressa Blainski, Vanessa Kaplum, Marli Miriam de Souza Lima, Tânia Ueda-Nakamura, Benedito Prado Dias Filho, João Carlos Palazzo de Mello and Celso Vataru Nakamura

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