October 2011
Juglone: A therapeutic phytochemical from Juglans regia L.
Juglans regia L. is a monoecious, heterodichogamous, deciduous tree species valued for its high-quality timber as well as its nuts. It belongs to the family Juglandaceae. Though, it is native to Central Asia, India, Nepal China and some part of Europe, it is being grown commercially in the USA, France, Italy and Spain for nut production. The nuts and plant parts of J. regia contain the aromatic secondary...
October 2011
Forest cultivated ginseng in Korea: All cure medicinal plants
Forest cultivated ginseng, Panax ginseng C. A. Meyer, is an important pharmaceutical plant in North Eastern Asia. The Korean peninsula is the best place to grow ginseng because the plant has stringent requirements for growth, such as high precipitation during the summer and an appropriately low minimum winter temperature. Advantageously, forest cultivated ginseng requires little maintenance....
October 2011
A review of diabetes mellitus
October 2011
Monograph of Vaccinium macrocarpon
Cranberry (Vaccinium macrocarpon) is a very useful drug in Unani system of medicine and Ayruvedic system of medicine. Research has suggested cranberry may be effective against UTIs (urinary tract infection) because it prevents Escherischia coli, the bacteria that cause most urinary tract infections, from attaching to the walls of the bladder. It only grows in open, sunny, wet areas in the colder...
October 2011
Hypoglycaemic activity of the ethanol extract of Ageratum conyzoides linn. shoots on alloxan-induced diabetic rats
Owing to the increasing prevalence of diabetes in Nigeria, there is a continuous search for antidiabetic phytomedicines. The hypoglycaemic activity of the ethanol extract of shoots ofAgeratum conyzoides Linn. was determined using alloxan-induced rats. Ethanol extract was prepared using a soxhlet extractor. The hypoglycaemic activity of ethanol extract of A. conyzoides was determined using alloxan-induced...
October 2011
Antiasthmatic activity of the methanolic extract of Physalis angulata Linn.
In this study the methanolic leaves extract of Physalis angulata Linn. (Solanaceae) (PAL) was investigated for anti-histaminic activity by usingisolated animal smooth muscle models (guinea pig ileum preparation, guinea pig trachea and rat fundus strip), where the plants extract possess inhibitory efficacy against histamine and 5 – HT. Acute toxicity study of the plant extract was also performed to...
October 2011
Phytochemical screening and antimicrobial activity of the plant extracts of Mimosa pudica L. against selected microbes
Mimosa pudica is the herb that shows sensation on touch. It has been identified as Lajjalu in Ayurveda and has been found to have antiasthmatic, aphrodisiac, analgesic, anti-inflammatory and antidepressant activities. In the present study the active phytocomponents of M. pudica were revealed using phytochemical analysis. The antimicrobial activity ofMimosa was studied using disk diffusion...
October 2011
Pharmacological profile of aqueous extract of Bridelia ferruginea stem bark in the relief of pain and fever
The pharmacological effects of the aqueous stem bark extract of Bridelia ferruginea were studied in rodents. Investigations were carried out on analgesic and antipyretic properties employing different experimental models in mice and rats. The analgesic activity was measured using the acetic acid induced-abdominal constriction and tail immersion tests. The antipyretic effect was assessed using the yeast-induced...
October 2011
The effect of drought stress on growth parameters, essential oil yield and constituent of Peppermint (Mentha piperita L.)
Peppermint (Mentha piperita L.) is one of the most important plants producing essential oil. Two experiments were conducted to determine the effect of drought stress on growth parameters, essential oil constituents and yield of peppermint. 5 levels of water deficit stress including D1 (100% field capacity-control), D2 (85% field capacity), D3 (70% field capacity), D4 (60% field capacity) and D5 (45% field...
October 2011
Effect of simultaneous ultrasonic/microwave assisted extraction on the antioxidant and antibacterial activities of burdock leaves
The effects of different extraction methods on the antioxidant and antibacterial activities of burdock leaves extracts were first investigated. The extracts of burdock leaves were prepared by 10 h maceration extraction (ME) and simultaneous ultrasonic/microwave assisted extraction (UMAE) with a significantly short operation time of 30 s. The UMAE extract exhibited 50.60% inhibition of lipid peroxidation, 51.22%...
October 2011
Medicinal plants as surface activity modifiers
Surface active agents have been used in pharmaceutical formulations for different purposes, so the study of the effect of these agent on biological membranes is necessary. The aim of this study is the evaluation of aqueous extract of Tribulus terrestris L., Trigonella foenum-graecum L. and Echium amoenum Fisch, that contain saponins on red blood cells (RBC) as a model of biological membranes....
October 2011
Antimicrobial and immunomodulatory effects of Aloe vera peel extract
The rapidly emerging rate of antibiotic resistance requires alternative solutions rather than new drugs. Aloe has been used for medical applications and exhibits antimicrobial activity as well as immunomodulation effects. Use of the aloe peel has not been considered, even though it may harbor many useful compounds. In this study, the antimicrobial activity of Aloe vera peel extract in distilled water...
October 2011
Effects of hydrolysis conditions on recovery of antioxidants from methanolic extracts of Nigella Sativa seeds
Nigella sativa (NS) has health promoting beneficial properties including antioxidant activity. In this study, the impact of acid and alkaline hydrolysis conditions on phenolic (TPC), flavonoid (TFC) contents and antioxidant activity of methanolic extracts from N. sativa (NS) seeds powder is evaluated. Total phenolic and flavonoid contents were evaluated according to Folin-Ciocalteu procedure and...
October 2011
Enhancement of induced apoptosis in human melanoma A375 by a combination of natural compounds
Jaceosidin, emodin and magnolol are natural compounds isolated from Chinese herbs and are reported to have anticancer properties; although a combination of natural anticancer drugs could increase the efficacy of anticancer activity. However, the combination of these compounds was examined by using MTT assay, cell cycle arrest, flow cytometry and western blot on melanoma A375. The results showed that the new combinations...
October 2011
Study of antivirus, antibacteria and immune functions of Gaoreqing freeze-dried powder
Gaoreqing freeze-dried powder was effective fraction extracted from Lonicera japonica Thunb.,Scutellaria baicalensis Georgi and Forsythia suspense (Thunb) Vahl. It was confirmed to have certain anti-virus, anti-bacterial effects and immuno-enhancing activities. Cell culture and influenza viral pneumonia model of mouse were used to study its antiviral effect. Plate culture and pathogenic...
October 2011
Sophora alopecuroides L. response to salt stress at germination and seedling growth stages
Sophora alopecuroides L. is a perennial herb that has been widely used in pharmaceutical industry due to the high alkaloid level in its seeds which can be considered for medical usages. In this study, response of S. alopecuroides to five NaCl concentrations (0, 50, 100, 150 and 200 mM) was investigated. The study was evaluated in two steps, seed germination and seedling growth. The results...
October 2011
Effect of fungal elicitor on carbon and nitrogen status and triterpenoid production in cell suspension cultures of Betula platyphylla Suk.
Carbon and nitrogen status, as well as triterpenoid production were investigated in cell suspension cultures of Betula platyphylla Suk. treated with fungal elicitor. The fungal elicitor was observed to inhibit the cell growth and enhanced triterpenoid production. The maximum triterpenoid production was 123.82 mg·L-1 DW in the 1-day elicitated cells, which was two fold higher than that of the...
October 2011
Seven alkaloids and their antibacterial activity from Hypecoum erectum L.
From the aerial part of Hypecoum erectum L., seven alkaloids, Protopine (1), Cryptopine (2), Allocryptopine (3), Hypecorinine (4), (-)-N-Methylcanadine (5), Oxohydrastinine (6) and N-Methylcorydaldine (7) were isolated. The structures of the seven compounds were established by 1H-NMR, 13C-NMR, DEPT and ESI-MS analyses. Compounds 2, 5 and 7 were obtained from this plant for the first time. The...
October 2011
Chemical composition and antifungal activity of Aleppo pine essential oil
The composition of spine essential oil of Aleppo pine tree from Ghazaouet (Tlemcen) extracted by hydro-distillation (yield: 0.3%) was investigated by GC_MS. Twenty-two compounds, representing 93.38% of the essential oil were identified. The main constituents are caryophyllene oxide (52%), thumbergol (9%), and humulene oxide (7.2%). The antifungal activity of this essential oil against Aspergillus flavus,...
October 2011
Effects of Lonicera japonica Thunb. on dextran sulfate sodium-induced experimental colitis in mice
We investigated the effects of buthanol (BuOH) extracts of Lonicera japonica on dextran sulfate sodium (DSS)-inducedq mice colitis. Body weight, histological indices such as crypt injury and inflammation score, biochemical factor such as serum amyloid (SAA) and MPO level data were evaluated. BuOH extracts of L. japonica reduced the crypt injury and inflammation score and showed markedly greater more...
October 2011
Bioactive chalcone from Indigofera pulchra
Extensive phytochemical investigations using silica gel column chromatography, gel filtration and preparative thin layer chromatography (TLC) led to the isolation of 2’ 4’- dihydroxy-4-prenyloxy chalcone from the methanol extract of Indigofera pulchra. The structure of this compound was elucidated with the help of NMR and mass spectroscopy. The analgesic effect of the compound was studied using acetic...
October 2011
Phytochemical properties and toxicity to brine shrimp of medicinal plants in Erute county, Lira district, Uganda
Erute county is known to have a number of medicinal plants that are used commonly as remedies of many ailments. The study was conducted in 54 parishes of Erute county and aimed at determining the phytochemical constituents and toxicity of the medicinal plants used by the community. Questionnaires, semi-structured interviews and focused group discussions were used to obtain ethnobotanical data of these plants. Field...
October 2011
The MAGi DNA extraction method for fresh tissues and dry seeds
The isolation of un-degraded, high-molecular-mass genomic DNA is essential for many DNA based molecular biology applications including long polymerase chain reactions (PCR), multiplex PCR, endonuclease digestion, Southern blot analysis and genomic DNA library construction studies. Although many protocols are available for the extraction of DNA from plant species, most of them require longer times and the size of...
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