Journal of
Cancer Research and Experimental Oncology

  • Abbreviation: J. Cancer Res. Exp. Oncol.
  • Language: English
  • ISSN: 2141-2243
  • DOI: 10.5897/JCREO
  • Start Year: 2009
  • Published Articles: 58

JCREO Articles

Epidemiology and association of risk factors with molecular data of oral cancer in Senegal sub-Sahara region

January 2024

Oral cavity cancers appear to be more common among head and neck cancers (HNCs). Its incidence and etiology vary from country to country. In this study, the aim is to describe the epidemiological profile and emerge the risk factors for oral cancer in Senegal and their association with genetic alterations. The study is prospective and was conducted on 54 patients and 54 controls. Epidemiological and clinicopathological...

Author(s): Mame Diarra Samb, Fatimata Mbaye, Henri Diatta, Mouhamadou Makhtar Ndiaye, Silly Toure and Mbacke Sembene  

Patient feeding experience during cancer chemotherapy in Ouagadougou

February 2023

This study describes the influence of chemotherapy on patients' eating habits in the context of resource-limited countries. This is a descriptive and analytical cross-sectional study of patients who have been prescribed chemotherapy and followed throughout this treatment at the Yalgado Ouedraogo University Hospital. We collected data on the initial eating habits and dietary coping strategies during chemotherapy...

Author(s): Augustin Tozoula Bambara, Yams Djamiratou Ouédraogo, Okobalemba Etienne Atenguena, Alice Cynthia Sama, Fayçal Akanni and Roger Sombié,  

Assessment of alternative approaches of primary cervical cancer screening among women in low-income environments

May 2021

Alternative techniques for detecting cancer of the cervix uteri alongside its early precancerous lesions still remain necessary for low income environments since morbidity and mortality due to cervical cancer continues to be on the rise. We recruited one thousand and seventy-seven women aged 15-55 years from selected study hospitals in Eastern Uganda and examined them using Papanicolaou (Pap) smear, direct visual...

Author(s): Emmanuel Eilu, Saheed Adekunle Akinola, Julius Tibyangye, Rasheed Omotayo Adeyemo, Martin Odoki, Aliero Almustapha Adamu, Sarah Kemuma Onkoba, Moindi Jeridah Kemunto, Ismail Adebayo Abyola and Charles Drago Kato,  

Prevalence of cervical intraepithelial neoplasia and its associated factors among women attending healthcare services in Eastern Uganda

May 2020

Cervical malignancy is still the leading cause of death for middle-aged women in the developing world. In Uganda, literature has shown that, cervical cancer incidence and death rates was 45.6 and 25 per 100,000 women respectively. However, the actual magnitude of cervical malignancy in Uganda might be higher since most of the cases are never reported. This study assessed the prevalence of cervical intraepithelial...

Author(s): Emmanuel Eilu, Adamu Almustapha Aliero, Martin Odoki, Julius Tibyangye, Saheed Adekunle Akinola, Ibrahim Ntulume, Okweny David, Matilda Angella Okech, and Charles Drago Kato,  

Head and neck lipomas: A clinicopathologic analysis of 36 cases

November 2019

Lipomas are common benign soft tissue tumors, with 15 to 20% of the cases affecting the head and neck region and 1 to 4% involving the oral cavity. The literature has many reported cases of head and neck lipoma but few comprehensive studies hence, the aim of this study was to review and analyze the clinical and histopathologic features of head and neck lipomas in Nigerians. A fifteen-year retrospective study evaluated...

Author(s): Stephen Babatunde Aregbesola, Bamidele Adetokunbo Famurewa, Olujide Oladele Soyele and Akinwumi Oluwole Komolafe  

Human natural killer (NK) cell activation by luteolin from Brucea javanica leaves

December 2018

There is growing interest in using natural substances from plants to potentially enhance anticancer activity. A key target in this respect is natural killer (NK) cells in order to generate an anticancer-immune response. Luteolin used in this study was derived from a local plant Brucea javanica leaves extract; through a bioassay-guided fractionation. The expression of interleukin-2 (IL-2) and interferon-γ...

Author(s): Norzila Ismail, Hasmah Abdullah, Veronique Seidel and Dino Rotondo  

The influence of life behaviour, diet, physical activities on the incidence of breast cancer among women attending Obafemi Awolowo University Teaching Hospital Complex, Ile-Ife

January 2018

The aetiopathogenesis of cancer has been linked to life behaviour in a significant percentage of cases. Overweight, sedentary lifestyle, smoking and the excessive use of alcohol have been shown to play important roles. This study is aimed at determining the effect of life behavioural patterns and diets in the incidence of breast cancer in Nigerians population. A prospective case-controlled study of 125 breast cancer...

Author(s): Arowolo O. A., Olasehinde O., Oyekunle A. A., Adisa A. O., Alatise O.I. and Adesunkanmi A. R. K.

Detection of cervical human papillomavirus in women attending for cervical cancer screening by visual inspection in Côte d' Ivoire

October 2017

Human papillomaviruses (HPV) cause precancerous lesions and cancers of the cervix. In Côte d'Ivoire, cervical cancer screening program based on visual inspection is the gold standard. This study aimed to detect high risk (HR) HPV DNA on women attending cervical cancer screening program based on visual inspection after application of acid acetic and Lugol. From March to December 2015, cervical samples from...

Author(s): Ouattara Abdoulaye, Yeo Alain, Blavo-Kouame E. B., Koffi Tchibeh F., Saraka Nguessan D., Oura Pierre K., Faye-Kette Hortense and Dosso Mireille

Retrospective study on gastrointestinal tract tumors in humans in Zaria, Kaduna State, Nigeria

May 2017

A retrospective study of gastrointestinal tract (GIT) tumors of humans in Zaria was carried out to determine the prevalence rates. Of the 124 human cases recorded in Ahmadu Bello University Teaching Hospital (ABUTH) Zaria, 39 (31.45%) had upper GIT tumors while 42 (33.87%) had tumors located in the lower GIT. All age groups were affected. The risk for developing tumors increased with age in cases studied. The affected...

Author(s): Mbuk E. U. and Amber E. I.

Prevalence of unilateral arm lymphedema among breast cancer patients one year after completing treatment at Cancer Diseases Hospital in Lusaka

September 2016

Lymphedema of the arm and/or hand is a long-term complication of breast cancer treatment.  Accurate estimates of the incidence and prevalence of lymphedema are lacking, as are the effects of this condition on overall quality of life. The objective of this study was to determine the prevalence of unilateral arm lymphedema among breast cancer patients one year after completion of treatment at Cancer Diseases...

Author(s): Victoria Mwiinga-Kalusopa, Catherine Ngoma

Mean platelet volume and mean platelet volume/platelet count ratio as markers for hepatocellular carcinoma in patients with chronic hepatitis C virus related cirrhosis

September 2016

Hepatocellular carcinoma (HCC) is the most common primary malignant tumor of the liver. The lack of efficient and precise HCC biomarkers prevents early detection resulting in a poor prognosis. Recently, mean platelet volume (MPV) and MPV/platelet count (PC) ratio have been proposed as potential markers of HCC. This study was carried out to verify MPV and MPV/PC ratio in diagnosis of HCC in Egyptian patients with chronic...

Author(s): Khaled Metwaly, Eman Abdel Sameea, Gasser El-Azab, Medhat Assem, Mohamed Abbasy, Talaat Zakareya and Gamal Abo Raia

Health related quality of life among breast cancer patients with unilateral arm lymphedema at cancer diseases hospital in Lusaka, Zambia

August 2016

This study aims to determine health-related quality of life (HRQOL) of breast cancer patients with unilateral arm lymphedema one year after completion of treatment at Cancer Diseases Hospital. The study design comprises of a cross sectional study, where we assessed the HRQoL controlling for patient demographics, cancer stages and treatment types. Short form of 36 interview schedule was used to assess HRQol and to...

Author(s): Victoria Mwiinga-Kalusopa, , Catherine Ngoma and Kennedy Lishimpi

Immunotherapy against cancer: A comprehensive review

July 2016

The endeavor of this paper was to review cancer immunotherapy which means the modulating and using of the patient’s own immune system to target the cancer cells rather than using an extrinsic means of therapy. The best way to prevent and remove infections is through the natural 'sterilising' action of the immune response that combines elements of both innate and adaptive immunity to ward off foreign...

Author(s): Minda Asfaw Geresu, Awel Feku Sultan, Seifudin Kassim Ahmed and Gezahegne Mamo Kassa

Diallyl disulfide protects against rectal cancer in vivo model of male rabbits: II-Analysis of histological and cytogenetic variations

April 2016

The present work was conducted to perform a short-term comparative analysis and evaluate the anti-neoplastic effects of diallyl disulfide on rectal carcinogenicity via histopathological changes, chromosomal aberrations, and mitotic index induced by 1,2-dimethylhydrazine on male rabbits (Orectolagus cuniculus). The histological changes that can be seen microscopically showed that 1,2-dimethylhydrazine at the suggested...

Author(s): Tito N. Habib, Mohammed O. Altonsy, Soheir A. Abd El-Raheem and Yassmin R. Bakeer

Clinicopathological and survival significance of BAT-25 and BAT-26 instability in breast cancer among Senegalese patients

August 2015

In some tumors, defects in mismatch repair enzymes lead to errors in the replication of simple nucleotide repeat segments. This condition is commonly known as microsatellite instability (MSI) because of the frequent mutations of microsatellite sequences. The primary aim of this study is to evaluate the clinicopathological and survival significance of BAT-25 and BAT-26 instability, in 60 patients with breast cancer....

Author(s): Fatimata Mbaye, Sidy Ka, Ahmadou Dem, Mamadou Kane and Mbacké Sembéne,

Review on vaccine design strategies against cancer

March 2015

Cancer is a leading cause of death worldwide, resulting in 8.2 million or 14.6% of all human deaths worldwide in 2012. More than 70% of all cancer deaths occurred in low and middle income countries; although the risk of developing/dying from it is still higher in the developed regions of the world, and tobacco use is the cause of about 22% of cancer deaths which is still a major public health problem worldwide that...

Author(s): Yimer Muktar, Negassa Feyissa, Tesfaye Sisay, Teshager Dubie, Jelalu Kemal and Yitagle Terefe

Oncogenic human papillomavirus (HPV) in women from Ghana

December 2014

Gynaecological or cervical cancer remains a significant public health problem worldwide, a situation from which Ghana is not exempt. Human papilloma virus (HPV) is an important agent of pre-invasive and invasive cervical cancer. Currently, over 70 genotypes of the virus have been identified, of which twenty or more have actually been isolated from or are reportedly associated with female genital lesions. Anecdotal...

Author(s): Brandful J. A. M.⊃, Bonney E.Y.⊃, Asmah R. H.⊃ and Apea-Kubi K. A.  

Detecting cancer at primary care level in developing nations by involving youth of a country

September 2014

After witnessing two cancer deaths in my family, I understood how hard it is for a family to bear the loss. So I strongly feel that a planned approach towards prevention and elimination of cancer, and especially lifestyle related cancers, is the need of the hour in developing nations where resources are limited. A large proportion of a nation’s population is comprised of young adults. They can make a huge...

Author(s): Smile Kajal

Effects of omega-3 fatty acids against Ehrlich carcinoma-induced hepatic dysfunction

March 2014

Omega-3 essential fatty acids (ω-3 FATs); found in the highest concentrations in fish oil, claim a plethora of health benefits. The present study aims to evaluate the biological effects of ω-3 FATs supplementation against Ehrlich carcinoma (EC) induced inflammation, oxidative stress, biochemical and histopathological alterations in the liver tissue of albino mouse. ω-3 FATs were orally administered via...

Author(s): Ussama Z. Said, Neamat H. Ahmed, Amina M. Medhat and Mustafa M. Mustafa

The prognostic value of IgA/[EBNA1+VCA-p18] on survival of nasopharyngeal cancer patients

March 2014

Undifferentiated (World Health Organization (WHO) 3) type of nasopharyngeal cancer (NPC) is strongly correlated with Epstein-barr (EBV) virus latent infection. Post-treatment viral reactivation is associated with relapsed or recurrence of NPC. Viral activation can be measured indirectly via plasma IgA responses towards EBV proteins such as EBNA1 and VCA-p18. This study aims at determining the prognostic value of...

Author(s): Kartika Widayati Taroeno-Hariadi, Djohan Kurnianda, Jajah Fachiroh, Bambang Hariwiyanto, Sagung Rai Indrasari, Camelia Herdini, Ibnu Purwanto, Salugu Maesadji, Retno Dwi Danarti, Mardiah Suci Hardianti, Ahmad Harijadi and Sofia Mubarika Haryana

Levonorgestrel-releasing intrauterine device for management of tamoxifen-induced menorrhagia in breast cancer patients

January 2014

This study aimed to evaluate the therapeutic yield of levonorgestrel-releasing intrauterine device (LNG-IUD) for management of tamoxifen induced menorrhagia in women who had mastectomy for treatment of breast cancer. This study included 34 patients who had breast cancer, underwent mastectomy, were maintained on tamoxifen post-operatively for at least 6 months, and had also newly developed menorrhagia throughout their...

Author(s): Mohamed Anwar El-Nory,  Gamal I. El-Habbaa and Gamal Ibrahim Rageh

Hypertrophic pulmonary osteoarthropathy as the presenting symptom of non-small cell lung cancer: A case report

January 2014

Hypertrophic pulmonary osteoarthropathy (HOA) is a disabling condition that may occur secondarily to primary lung carcinoma. Management of joint pain in patients with HOA is challenging, and treatment options are experimental. Here we report an unusual case of HOA in a 54 year-old man who presented with fever, rash and arthralgia as initial symptoms of an underlying non-small cell lung cancer. He did not respond to...

Author(s): Sheila Nguyen and Mehrnaz Hojjati

Solid-phase total synthesis of cyclic pentapeptide Longicalycinin A, by using 2-chlorotrityl chloride resin

November 2013

Naturally isolated cyclic pentapeptide Longicalycinin A, which showed cytotoxicity to Hep G2 cancer cell line with an IC50 value 13.52 μg/mL, has been successfully synthesized by solid-phase methodology with Fmoc/t-Bu protecting schemes via solution-phase macrocyclization. 2-chlorotrityl chloride resin was used as solid support. Solution phase macrocyclization of linear pentapeptide precursor was carried out by two...

Author(s): Waqar Ahmad, Farzana Shaheen, Yunshan Zhou and Lijuan Zhang

Mapping Angiogenic Cells CD31 (PECAM1) and CD45 in PCa and BPH Biopsies

November 2013

  Molecular characterization of PCa and BPH using the angiogenic tissue markers CD31 and CD45 to differentiate between the two major types of prostate gland disorders is investigated. 8 clinically characterized biopsies were analyzed at the Histopathology Laboratory of the Ekiti State University Teaching Hospital; the tissue sections were processed for antigen retrieval and were labeled with anti-CD45 and...

Author(s): Adegun P.T, Ogundele O.M, Falode D.T, Taiwo O.J, Ajonijebu D.C, Omoaghe A.O and Kobomoje O.S

Erythrina velutina and Bryothamnion seaforthii lectins binding to proteins of primary central nervous system tumors

November 2012

This research was done to examine the interaction of lectins with glycoconjugates expressed on Primary CNS tumors using lectins from marine algal Bryothamnion seaforthii(BSL) and seeds of Erythrina velutina (EVL) Fluorescein isothiocyanate (FITC)-labeled. Samples of different tumor types obtained from the Neurology Service of Sobral-Brazil were processed for histopathologic...

Author(s): Felipe M. Conrado, Luis E. T. A. Furtado, Alrieta H. Teixeira, Nara L. P. Coutinho, Alexandre H. Sampaio, Benildo S. Cavada, Mirna M. Bezerra, Antonio Alfredo R. Silva, Francisco Cesar B. Barbosa, Hellíada V. Chaves, Gerardo C. Filho and Vicente P. T. Pinto

A review of clinical trials of chemotherapy for pancreatic cancer

November 2012

Chemotherapy is playing an important role in treating pancreatic cancer, either when used alone or when combined with surgery and radiotherapy. We summarized 80 eligible clinical trials published from January in 2006 to June in 2011 and discussed the future development of chemotherapy in the treatment of pancreatic cancer. All the clinical trials were divided into 5 groups: single-agent regimen (14 trials), binary...

Author(s): Hui Zhu, Xinwei Wang, Xiagang Luo, Xiang Yu and Chunzhao Yu

Evidence of a positive correlation between accelerated oestrogen receptor phosphorylation and breast cancer progression

December 2011

Estrogen receptor beta (ERβ) is predicted to play an important role in prevention of breast cancer development and metastasis. Phosphorylation of Estrogen receptor alpha (ERα) has been proven to be involved in the progression of breast cancer and it is believed oestrogen receptor beta too phosphorylated at multiple sites within the protein upon ligand binding although the exact function of this...

Author(s): Mohamed Fareez Meerasahib and Amer Hamzah Asseri

Loss of heterozygosity (LOH) of deleted in colorectal cancer (DCC) gene and predisposition to colorectal cancer: Significant association in colorectal cancer patients of Kashmir

November 2011

Loss of heterozygosity (LOH) of deleted in colorectal cancer (DCC) gene, a putative tumour suppressor gene has been implicated in development of various cancers. Here we aim to study the frequency of LOH of DCC gene in colorectal cancer (CRC) patients of Kashmir and further to assess any association with etio-pathological factors. Genomic DNA from 80 confirmed CRC tissue samples as well as adjacent normal...

Author(s): Nighat P. Khan, Arshad A. Pandith, Mahboob U. l. Hussain, Adfar Yousuf, Mosin S. Khan, Mushtaq A. Siddiqi, Khrusheed A. Wani and Syed Mudassar

Antitumor potential of an acetogenin isolated from the seed extracts of Annona squamosa Linn.

November 2011

Ethanolic herbal extract residue of the seeds of Annona squamosa Linn. were tested against Dalton’s Lymphoma Ascites (DLA) tumour cells. Then its effect on the increased lifespan of mice with DLA tumour cells was studied. At high and low dosages, it exhibited 66.67 and 56.25% increase in the lifespan. Percentage of haemoglobin (Hb) and red blood cell (RBC) counts of treated were higher than that of...

Author(s): R. M. Ganesan and K. Muthuchelian

Preliminary analysis of radiation dose effects to rat femora microstructure using synchrotron radiation computed microtomography

October 2011

In this work we investigated the consequences of irradiation in the femur of rats to a radiation dose of 5 Gy. Three different sites in femur specimens were imaged using synchrotron radiation microcomputed tomography to assess trabecular bone microarchitecture: head, distal metaphysis and distal epiphysis. Histomorphometric quantification was extracted directly from the 3D tomographic images using synchrontron...

Author(s): Liebert Parreiras Nogueira, Christiano Jorge Gomes Pinheiro, Regina Cély Barroso, Delson Braz, Carlos Eduardo de Almeida, Cherley Borba Andrade and Giuliana Tromba

Benign breast tumors in Red Sea State, Sudan

October 2011

The majority of breast tumors are benign. Some of these tumors carry risk that change into cancer. So, it is important to know the different histopathological patterns of the benign breast lesions. This will help in the proper diagnosis of the lesion and build up of potent programs against the cancer. This research classifies benign breast diseases according to their frequency in Red Sea State, Sudan and compares them...

Author(s): Ali K. Ageep

Experimental therapy against ovarian cancer by tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) gene driven by human telomerase reverse transcriptase (hTERT) promoter

September 2011

TRAIL functions as a soluble cytokine killing various cancer cells with limited toxicity to most normal cells. Human telomerase reverse transcriptase (hTERT) promoter is known to selectively drive transgene expression in many human cancer cells. In this study, we aimed to determine whether the hTERT promoter could efficiently mediate more specific TRAIL gene therapy in ovarian cancer cells. We demonstrated...

Author(s): Hongmei Li and Yuecheng Yu

Chronic myeloid leukemia: Attributes of break point cluster region-abelson (BCR-ABL)

September 2011

Chronic myeloid leukemia is a molecular fault from neoplastic transformation of hematopoietic stem cells. It is elicited by an extensive spectrum of “fused oncoproteins” which are necessitated in the disease refractoriness. It docks a miscellany of fusion transcripts originating from chromosomal rearrangements. Additionally, vulnerability to genomic rearrangements is particularly enhanced in chronic myeloid...

Author(s): Aamir Rana, , Sabir Hussain Shah, Nazia Rehman, Shaukat Ali, Ghulam Muhammad Ali, Shahzad Bhatti, and Ammad Ahmad Farooqi,

Patient-specific quality assurance for the treatment of intensity modality radiation therapy of nasopharyngeal carcinoma

August 2011

Nasopharyngeal carcinoma is the most common malignant tumor of the nasopharynx. The aim of this study was to assess and evaluate the significant of performing patient specific quality assurance (QA) for patients diagnosed with nasopharyngeal carcinoma treated with intensity modulated radiation therapy (IMRT). Ten pretreatment IMRT plans were selected for this study. The ten selected plans were treated with the...

Author(s): H. I. Al-Mohammed and F. H. Mahyoub

Primary neuroendocrine carcinoma of the breast: A rare and distinct entity

August 2011

Neuroendocrine tumor of the breast is a rare tumor that is under diagnosed and treated. This is a retrospective study over three years of neuroendocrine breast carcinoma cases seen at the National Institute of Oncology in Morocco between May 2007 and 2010. We analyzed various characteristics: Patient demographics, histological diagnosis, disease stage, treatment effects and outcome, in 7 non-metastatic...

Author(s): S. Ghanem, H. Kabaj, S. Naciri, M. Glaoui, N. Ismaili, N. Benjaafar and H. Errihani

Down regulation of galectin-3 in primary tumor tissues of breast predict axillary lymph node metastasis

June 2011

Identification of axillary lymph node metastasis in breast cancer patients is a challenge in routine pathology practice. Serial sectioning and immunohistochemistry is labor intensive and cannot be followed even for sentinel node examination. So identification of a biomarker predicting axillary lymph node metastasis in primary tumor tissue is of great interest. Galectins are a family of low molecular weight...

Author(s): K. Sujathan, Thara Somanathan, Nimi G. K., Preethi Sara George, Elizabeth K. Abraham and P. Remani

Genetic polymorphisms of GSTM1 and GSTT1 genes and endometrial cancer in Basrah, South of Iraq

June 2011

The genes glutathione S- transferase M1 (GSTM1) and GSTT1 involved in phase II metabolism catalyse glutathione – mediated reduction of exogenous and endogenous electrophiles. A case control study was designed to identify association between polymorphisms at GSTM1 and GSTT1 genes and endometrial cancer risk. Genotype frequencies in 50 patient’s women with endometrial cancer...

Author(s): Adnan Issa Al-Badran

Photochemical internalization: Maximizing the potential of siRNA in cancer therapy through spatially and temporally controlled endolysosomal escape

April 2011

A major obstacle for cancer therapies is the lack of targeted delivery of therapeutics. To compensate, existing drug treatments rely on high dosages and frequent administrations. This results in adverse effects in the patient due to the drugs failure to discriminate between normal body cells and tumor cells. The discovery of RNAi (RNA interference) has radically opened possibilities to the advancement of cancer...

Author(s): Md Iqbal Touhid, B. S.

Imaging modalities in head and neck cancer patients-overview

April 2011

Accurate staging and timely assessment in head and neck cancer patients is critical for initiating appropriate treatment strategy. Therefore, pre-treatment imaging in diagnosis is of great importance. Computerized tomography, introduced in the early 70s, followed by magnetic resonance imaging, positron emission tomography, refinements in ultrasonography, and advances in nuclear medicine and applications such as sentinel...

Author(s): M. E. Sham and S. Nishat

Long term remission with 6-Mercaptopurine in refractory Evan’s syndrome

February 2011

The management of Evan’s syndrome remains a challenge and innovative approaches are needed. Initial therapeutic failure, relapses after initial response and refractoriness to treatments are typical. Options for second-line therapy include immunosuppressive drugs, especially cyclosporin or mycophenolate mofetil; vincristine; danazol or a combination of these agents. We report here a long-term remission of...

Author(s): I. Tazi, H. Nafil and L. Mahmal

Correlation between visual inspection of the cervix and pap smear test for cervical cancer screening

January 2011

Cancer of the cervix, although a preventable disease has remained a common genital cancer in Nigeria, where most women rarely ever undergo cervical cancer screening. The reasons commonly cited in several studies for this abysmal situation are the absence of routine and organized screening programme, lack of knowledge about cervical cancer screening and cost. Visual inspection of the cervix, which is easy to do, cheap...

Author(s): S. U. Mbamara, C. O. Ukah, O. Ikpeze, Okonkwo Jen and  V. Onyiaora

The effectiveness of high dose rate brachytherapy using a special applicator set with external beam radiation treatment and chemotherapy followed by surgery as a treatment of adenocarcinoma of the esophagus: A case series of single institution with literature review

January 2011

Our study looked at patients with esophageal adenocarcinoma treated with high dose rate brachytherapy (HDR-BT) followed by external beam radiation treatment (EBRT) and chemotherapy with and without surgery to find local response using special HDR-BT delivery catheter, Bonvoisin-Gerard Esophageal Applicator (BG Applicator). We reviewed eight patients’ charts with adenocarcinoma of esophagus (Median age = 63.5...

Author(s): Mihir Raval, and Nicolas Zouain,

Investigation of breathing maneuvers using free breathing and video biofeedback techniques during radiation therapy treatment for non small cell lung cancer patients

December 2010

The goal of radiation therapy treatment increases as the breathing motion decreases, which then will lead to desirable and accurate conformal dose distributions for mobile lung cancer tumor. Twelve healthy volunteers of age ranges between 18-63 years, (5 females and 7 males) were randomly selected for the study in the breathing training methods using free breathing and video biofeedback breathing. The free breathing...

Author(s): H. I. Al-Mohammed

Lectins isolated from Brazilian beans as markers of membrane glycoconjugates of human colon cancer cells

December 2010

TIn this preliminary study the carbohydrate-binding activity of 10 plant lectins from the Diocleinae subtribe Canavalia ensiformis (Con A), Canavalia brasiliensis (Con Br), Canavalia bonariensis (Con Bo), Canavalia grandiflora (Con Gr), Canavalia maritima (Con M), Dioclea grandiflora (DGL), Dioclea guianensis (Dgui), Dioclea virgata (Dvir), Dioclea violacea (Dvio) and Dioclea rostrata (Dros) was studied to determine...

Author(s): V. P. T. Pinto, E. H. Teixeira, A. H. Teixeira, V. A. Carneiro, G. Cristino-Filho, D. Dus, H. Debray, A. H. Sampaio and B. S. Cavada

Epstein Barr virus latent membrane protein-1 (LMP-1) expression and angiogenesis in Indonesian nasopharyngeal carcinoma (NPC)

November 2010

The pivotal role of Epstein Barr virus latent membrane protein 1 (LMP-1) in angiogenesishas been concluded from several in vitro experiments. However, there were very limited and inconsistent data on the correlation between LMP-1 and angiogenesis from clinical samples. Therefore, we aimed to investigate the correlation between LMP-1 and angiogenesis from Indonesian nasopharyngeal carcinoma (NPC). Forty cases...

Author(s): Mardiah Suci Hardianti, Johan Kurnianda, Harijadi, Kartika Widayati Taroeno-Hariadi, Rizka Humardewayanti Asdie and Bambang Hariwiyanto

Primary renal plasmacytoma: Case report and literature review

November 2010

Extramedullary plasmacytoma (EMP) results from uncontrolled plasma cell proliferation and consists of monoclonal plasmacytic infiltration without bone marrow involvement. These tumors occur most commonly in the head and neck region, followed by gastrointestinal tract, central nervous system, thyroid, breast, parotid gland, testis and lymph nodes. Primary renal plasmacytoma is very rare. We report a primary renal...

Author(s): Gui Fen Yang, Hong Zhu, Long Jiang Zhang and Guang Ming Lu

Ultrastructural changes in premalignant and malignant lesions of the uterine cervix with papillomavirus infection

September 2010

The main purpose of this study was intended to determine the possible ultrastructural relations among the human papilloma virus infection, angiogenesis and cellular infiltrate in premalignant and malignant lesions of uterine cervix. 58 samples of cervix were obtained from patients of the ambulatory “Maria Teresa Toro” Aragua, Venezuela, with cervical intraepithelial neoplasia (CIN) and human papillomavirus...

Author(s): Ivis J. Graterol⊃, Hector J. Finol⊃, Maria Correnti⊃ and Maira Ávila⊃

Survival disparities in non-small cell lung cancer patients receiving radiation treatment: An investigation of race and gender

September 2010

Multiple studies evaluating non-small cell lung cancer disparities reveal male gender and African American race as independent predictors for poorer outcome. This study aims to evaluate the prognostic factors affecting survival of non-small cell lung cancer patients receiving radiation treatment at the University of Washington and to investigate whether race and gender disparities persist at the level of access to...

Author(s): Yogesh Khanal, Julie Eaton, Janelle Pakish, Philemon Yen, Renato Martins, Laurie Carr, Keith Eaton and Shilpen Patel

The popliteal lymph node group as a naturally positioned model for research on lung cancer metastasis

September 2010

Lung cancer originates so close to the pulmonary veins that penetration into the blood circulation is naturally assured. Despite such excellent hematogenous opportunities, it is the lymphogenous route that brings about centrifugal lymph node involvement as low down as the abdomen. Therefore, it is hypothesized that the more distant popliteal nodes should be purposively harvested ethically, cut...

Author(s): W. I. B. Onuigbo

Long survival in patients with metastatic leiomyosarcoma of the uterine corpus: A report of 2 cases

April 2010

Leiomyosarcoma of the uterus is relatively uncommon in Ahmadu Bello University Teaching Hospital, Zaria - Nigeria and generally has a poor prognosis. A report of palliative treatment for invasive leiomyosarcoma of the uterine corpus with pulmonary metastases in 2 women is presented. Both patients presented with advanced bulky locoregional and metastatic disease. The patients had palliative care using multimodality...

Author(s): S. A. Adewuyi, M. S. Zayyan, P. I. Onwuhafua, M. O. A. Samaila, A. H.Rafindadi and A. O. Oguntayo

Page 1 of 2, showing 50 records out of 58 total, starting on record 1, ending on 50