November 2011
Effect of arbuscular mycorrhizal fungi and phosphorus concentration on plant growth and phenols in micropropagated Aloe vera L. plantlets
The objective of this work was to investigate the effect of two arbuscular mycorrhizal fungi (AMF) and different phosphorus (P) concentrations on growth and phenolic concentration inAloe vera L. plantlets obtained from micropropagation. Plantlets were multiplied in vitro, acclimatized and inoculated with Glomus claroideum or Glomus fasciculatum at three P concentrations, that is, 0.3,...
November 2011
Antinociceptive profiles and mechanisms of orally administered Aster Koraiensis extract in the mouse
In the present study, the antinociceptive profiles of Aster koraiensis extract (AKE) were examined in ICR mice. AKE administered orally (200 mg/kg) showed an antinociceptive effect as measured by the tail-flick and hot-plate paw-licking tests. In addition, AKE attenuated the writhing numbers in the acetic acid-induced writhing test. Moreover, the cumulative response time of nociceptive behaviors induced by an...
November 2011
Erythrophleum africanum Afzel. (Caesalpiniaceae), an African toothpick: Phytochemical screening, total flavonoid content and antioxidant activity
Erythrophleum africanum is an endangered West African medicinal plant because of the large-scale use of its stems as toothpicks. Phytochemical screening (preliminary test and thin layer chromatography (TLC) method), a quantitative analysis of total flavonoids, anthocyanidins and radical scavenging activity (2,2’-diphenyl-1-picrylhydrazyl (DPPH) method) of stems of E. africanum were undertaken....
November 2011
Validation of a high performance liquid chromatography (HPLC) method for the quality control of the Traditional Chinese Medicine (TCM) formulation, Traditional Chinese formula Huanglianjiedutang (HLJDT)
The aim of this study was to optimize a high performance liquid chromatography (HPLC) method for the simultaneous quantification of the four main compounds geniposide, berberine, baicalin and crocin present in the Traditional Chinese formula Huanglianjiedutang (HLJDT). This formula contains Coptidis Rhizoma, Radix Scutellariae, Cortex Phellodendri and Fructus Gardeniae in a ratio of 1.5: 1: 1:...
November 2011
Intervention study of Ginkgo biloba extract in rat model of lipid-induced insulin resistance
Our research focused on the correlation between IR and glucolipid metabolism, vascular endothelial dysfunction and steatohepatitis. Then to provide evidence of Ginkgo on early-stage prevention of IR related diseases in a rat model. Forty male SD rats were equally randomized to four groups: normal group, model group, Ginkgo group and rosiglitazone group. Blood samples and serum biochemical indicators were...
November 2011
Antioxidative and neuroprotective effects of Loranthus parasiticus (L.) Merr (Loranthaceae) against oxidative stress in NG108-15 cells
The antioxidative and neuroprotective effects of Loranthus parasiticus (L.) Merr(Loranthaceae) were investigated for the first time. L. parasiticus ethanol extract (LPEE), L. parasiticus ethyl acetate fraction (LPEAF), and L. parasiticus aqueous fraction (LPAF) were evaluated and exhibited antioxidative activity in a dose-dependent manner. LPAF exhibited the lowest...
November 2011
Anti-microbial efficacy and biochemical analysis from different parts of Acacia nilotica L. and Ricinus communis L. extracts
The present study was under taken to explore the potential of Acacia nilotica L and Ricinuscommunis L as antimicrobial agents in relation with various important bio-molecules and to check their correlation as antimicrobial agent. In present study water and methanol extract (20%) of different parts of A. nilotica and R. communis showed good inhibition against Gram positive...
November 2011
Status of management of diabetes mellitus by traditional medicine practitioners in Nigeria
Traditional medicine (TM) as practiced in Nigeria is involved with the management of diseases such as (HIV/AIDs), malaria, tuberculosis, diabetes mellitus, hypertension, fungal infections, and cancerous growths among others. Diabetes mellitus is a universal health problem affecting human societies at all stages of development. The prevalence of diabetes mellitus has been increasing steadily in Nigeria and this trend...
November 2011
Protective effect of milk thistle and grape seed extracts on fumonisin B1 induced hepato- and nephro-toxicity in rats
Fumonisin B1 (FB1) is a mold metabolite produced by Fusarium species that is frequently found in corn worldwide, it is toxic to both liver and kidney. Hepato- and nephro-toxicity were induced in rats by feeding them with FB1 contaminated corn. Evidence of those toxicities were observed after 60 days by an increase in the serum activity alanine aminotransferase (ALT) to 78%, creatinine to 65% and urea to 30%,...
November 2011
Effects of salidroside on the protection of diabetic encephalopathy and improvement of abilities of learning and memory in rat
Salidroside, a phenol glycoside isolated from Rhodiola rosea, has been reported to have many pharmacological properties, among which are the protective effects against neuronal death. Salidroside has the best pharmacological effects at the concentration of 50 mg/kg Salidroside (po) for rodents. A diabetic encephalopathy rat model has been generated in this research. After treating with salidroside, the blood...
November 2011
Dan-Shen-Yin has integrated protective effects in diabetic atherosclerosis rat models
Dan-Shen-Yin (DSY) is a famous traditional Chinese formula. We determined its integrated protective effects mechanisms of DSY in diabetic atherosclerosis rat model. DSY (5 or 10 g/kg/day for 4 weeks) was orally administrated to the diabetic atherosclerosis rats, which were induced by nitric oxide inhibition ( L-NAME in drinking water, 1 mg/ml) plus high-fat diet. At the end of the experiments, the serum level of...
November 2011
The Cuscuta kotschyana effects on breast cancer cells line MCF7
Cuscuta kotschyana Boiss is classified as a member of Convolvulaceae family. This plant is mainly a central Asian taxon. Cuscuta is a parasitic plant that wraps around other plants for nourishment. Previous studies have indicated that Cuscuta could possess anticancer and immunostimulatory activities. The chemical constituents of Cuscuta mainly comprise flavonols like quercetin,...
November 2011
Medicinal Resources of the Miombo woodlands of Urumwa, Tanzania: Plants and its uses
A study was done to document different plants and their use for primary health care by communities around the Miombo woodland of Urumwa, Tanzania. Data collection was based on semi-structured interviews and discussion with key stakeholders. G-tests were carried out to seek differences in ethnobotanical knowledge between women and men. 110 plant species were documented to have 74 medicinal uses. Men were found to be...
November 2011
Wound healing properties of Eucheuma cottonii extracts in Sprague-Dawley rats
Wounds are unavoidable events of life and arise due to agents that induce stress or injury. Wound has been a menace the world over and healing is a survival mechanism and represents an adaptation to the maintenance of normal anatomical structure and function. The objective of this study was to evaluate the potential wound healing properties of ethanolic and aqueous extracts of Eucheuma cottonii. A two centimeter...
November 2011
Photochemical targeted drug delivery of liposomal membrane embedded photoreceptor hypericin
Hypericin embedded in liposome loaded with oxytetracyclin as a model drug was used as a drug delivery system. Two liposomal systems were prepared, sample (I) and sample (II). In sample (I), liposomes incorporated with hypericin as a photoreceptor and loaded with oxytetracyclin drug, while in sample (II), liposomes loaded with oxytetracyclin drug and incorporated with hypericin as a photoreceptor and alpha tocopherol...
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