International Journal of
Genetics and Molecular Biology

  • Abbreviation: Int. J. Genet. Mol. Biol.
  • Language: English
  • ISSN: 2006-9863
  • DOI: 10.5897/IJGMB
  • Start Year: 2009
  • Published Articles: 119

IJGMB Articles

December 2019

Characterisation of three morphotypes of Solenostemon rotundifolius [(Poir.) J. K. Morton] cultivated in Burkina Faso using quantitative traits

Evaluation of intra specific variability is a key step toward conservation and sustainable use of species. This study was carried out to describe the morphotypes of Solenostemon rotundifolius (Lamiaceae) based on quantitative traits. Three accessions (E02, E35 and E20), representing the morphotypes “A”, “B” and “C” were characterised in Randomised Complete Block Design with three...

Author(s): Romaric Kiswendsida NANEMA, Zakaria KIEBRE, Renan Ernest TRAORE, Aminata Hamidou BA and Francis KUSI

December 2019

Primary morphological characterization of West African dwarf (Djallonké) ewes from Côte d’Ivoire based on qualitative and quantitative traits

Phenotypic characterization is used to identify and document diversity within and between distinct breeds, based on their observable attributes. Study to assess the body characteristics and variability of 204 Djallonké (West African dwarf) ewes was conducted in three agro-ecological zones (central, western and northern) of Côte d’Ivoire, from November 2016 to April 2017. Animals were described using...

Author(s): N’Goran K. Edouard, Kouadja G. Severin, Kouassi N. Cyrille, Loukou N. Etienne, Eka Jean Yves, Dayo G. K. Charles, Sangare Mamadou and Yapi-Gnaore C. Valentine

December 2019

Assessment of radio-sensitivity for three cowpea genotypes to gamma irradiation

Cowpea (Vigna unguiculata [L.] Walp) is an important food legume. However, production is limited by various biotic and abiotic constraints in sub-Saharan Africa and reduced genetic variability hinders crop improvement efforts. Gamma ray irradiation has been used as a mutagen to create variability but optimal dose determination is a prerequisite to maximize the recovery of mutant plants. In this study, three genotypes...

Author(s): Karidiatou Gnankambary, Teyouré Bénoît Joseph Batieno, Nerbéwendé Sawadogo, Mahamadou Sawadogo, Djibril Yonli and Tinga Jeremy Ouédraogo

December 2019

Coexistence between (TOHO-type and BES-type) extended-spectrum β-lactamase genes of identified enterobacteria at Saint Camille Hospital, Ouagadougou, West Africa

Coexistence between the TOHO-type and Brazilian extended-spectrum (BES)-type of extended-spectrum β-lactamase (ESBL)-produced by bacteria caused public health issue. Several studies have been reported on the coexistence between blaTEM, blaCTX-M and blaSHV genes in ESBL in broad spectrum enterobacteria. The present study involved the prevalence of coexistence of blaTOHO and blaBES genes in enterobacteria identified...

Author(s): Mètuor-Dabiré Amana, Sougué Serge, Tiemtoré Rahimatou Yasmine Wend-kuni, Zohoncon Théodora Mahoukèdè, Bangré Yasmine Aminata, Ouédraogo Paul, Kabré Elie and Simporé Jacques,

December 2019

Inheritance of maize (Zea mays L.) leaf traits

Maize leaf plays an important role in the synthesis of organic compounds. It hosts the interception of light energy and conversion to organic energy, and the capture and assimilation of carbon dioxide in order to produce food. In this study, we explore the heritability of the maize leaf length, leaf width, and the number of leaves of two maize genotypes, JNE and BLC. The estimates of heritability varied from 0.2 to...

Author(s): Seka, D., Bonny, B. S., Adjoumani, K., Alla Eby, Y. G. H., Yoboué, A. N. ,  Sié, R. S. and Adepo-Gourene B.A.  

December 2019

Prevalence and genetic diversity of Plasmodium falciparum in patients attending regional health center in Daloa, Côte d'Ivoire

Malaria is a parasitic disease defined as a major problem of public health in Côte d'Ivoire. One of the constraints of the control of this disease might be the genetic diversity of the main pathogen, Plasmodium falciparum. This study aims to evaluate the genetic diversity of Plasmodium falciparum in individuals at the regional health center in Daloa, Côte d’Ivoire. A total of 380 blood samples were...

Author(s): Mathurin Koffi, Innocent Allepo Abe, Bernardin Ahouty Ahouty, Dieudonné Silué, Thomas Konan Konan and Abiba Sanogo Tidou

June 2019

Investigation of polymorphisms of exon 1 region of OsHKT1;5 gene in high yielding rice

This study was carried out to analyze the polymorphic region of exon 1 of OsHKT1;5 of 22 high yielding rice varieties that are salt tolerant. The result of the phenotypic screening for salinity stress was done using the standard protocol of the International Rice Research Institute which recorded that all rice varieties developed very well under control condition, 85.38% were quite tolerant to salinity treatment of...

Author(s): Nguyen Thi Pha, Nguyen Thi Phung, Nguyen Thi Ngoc Truc, Do Tan Khang and Tran Dinh Gioi

September 2018

The characterization of Citrus sp. from Parang Island Karimunjawa based on morphological, DNA barcoding and nutritional analysis

The Citrus sp. from Parang Island Karimunjawa is a wild type of Citrus plant that grow on salt area and exhibits a high level of vitamin C.  Due to its ability, morphological, molecular and nutritional characterization needs to be carried out to improve its potential. The study was carried out at the Biotechnology Laboratory and the Integrated Laboratory of Diponegoro University from 2016 to 2017. The...

Author(s): Hermin Pancasakti Kusumaningrum, Anto Budiharjo, Agung Suprihadi, Yuriza Eshananda, Annisa Fadillah and Dina Rahayuning Pangestuti  

April 2018

Use of expressed sequence tags-derived simple sequence repeat (SSR) markers for population studies of released and elite sweet potato

Development of improved varieties of sweet potato to meet specific end users in the sub-Saharan African region has the potential of transforming the crop’s market, consumption and health benefits. Molecular biology techniques such as fingerprinting are key to crop improvement, and critical for numerous genetic studies. This study, carried out in Ghana, seeks to determine genetic relatedness among two populations...

Author(s): Marian Dorcas Quain, Kwadwo Adofo, David Appiah-Kubi, Ruth Naa Prempeh, John Asafu-Agyei, Belinda Akomeah and Harrison Dapaah

March 2018

Unravelling genetic make-up of some Musa hybrids and selected Musa accessions using molecular and morphological characterization

Plantains are important staples in sub-Saharan Africa, however, production has been saddled by several constraints including pests and diseases and lack of improved technologies. In regard to genetic study, morphological characterization has identified about 100 local accessions to exist in Ghana. However, limited molecular characterization has been done on plantains. Characterization based on morphologic...

Author(s): Marian D. Quain, Adelaide Agyeman, Emmanuel Okyere and Beloved M. Dzomeku  

December 2017

De novo assembly and characterization of transcriptome and microsatellite marker development for Taro (Colocasia esculenta (L.) Schott.)

Taro (Colocasia esculenta. (L.) Schott) is a genus of perennial plants that is widely distributed in the tropics or subtropics of Asia, Africa and America, which is the fourteenth most consumed vegetable of the world. However, molecular genetic research of Colocasia has been hindered by the insufficient genomic and transcriptome information. Here, the transcriptome of taro variety ‘Jingjiang Xiangsha’ from...

Author(s): Li Wang, Jianmei Yin, Peitong Zhang, Xiaoyong Han, Wenqi Guo and Chunhong Li

November 2017

Broad sense heritability and genetic advance for grain yield and yield components of chickpea (Cicer arietinum L.) genotypes in western Ethiopia

Genetic variability is a prerequisite to crop improvement. The objective of the present study was to assess and quantify the genetic variability, estimate heritability and genetic advance for yield and yield contributing characters of released and pipeline chickpea varieties based on agro- morphological traits. A total of 16 chickpea materials (8 improved varieties, 7 advanced lines, and one local check) were planted in...

Author(s): Biru Alemu, Kassahun Tesfaye,, Teklehaimanot Haileselassie and Dagnachew Lule

May 2017

Genetic polymorphism of vesicular monoamine transporter 1 gene (SLC18A1) in Emirati population

Vesicular monoamine transporters (VMATs) are an important target for biological research in neuropsychiatric disorders. Recent studies indicated that VMAT1 is expressed in the brain, thus making transporter plausible candidate genes for neuropsychiatric disorders. Furthermore, several recent genetic case-control studies have documented an association between common missense variations in the VMAT1 gene and...

Author(s): Abdullah Al Mutery, Walaa Kamal, Hawraa Abduljalil Hussein Al Bloushi, Mary Sebastian Manjuran and Naushad Rais

April 2017

Biodiversity of uncultured bacteria in hypersaline lakes, Siwa oasis, Egypt, as determined by polymerase chain reaction and denaturing gradient gel electrophoresis (PCR-DGGE) of 16S rRNA gene phylotypes

Bacterial populations within hypersaline lakes often exhibit uncultured unique species. Polymerase chain reaction-denaturing gradient gel electrophoresis (PCR-DGGE), followed by sequencing of 16S rRNA gene approach was applied in order to explore, for the first time, the bacterial communities within the hypersaline Lakes, Aghormy, Zeiton and Maraqi, Siwa Oasis, Egypt. The DGGE profile displayed 12 phylotypes of 16S rRNA...

Author(s): Hosam E. Elsaied, Mohamad Saad Abd El-Karim and Mai A. Wassel

March 2017

The cichlid 16S gene as a phylogenetic marker: Limits of its resolution for analyzing global relationship

The phylogenetic utility of the 16S gene in cichlids is assessed. Eighty-six (86) partial sequences belonging to 37 genera of cichlids from the Genbank was analyzed. The alignment had four hundred and sixty three (463) basepairs with 337 conserved sites and 126 variable sites. Base compositional bias is similar to that found in higher organism with Adenine having the highest average of 30.3%, followed by cytosine,...

Author(s): Olusola B. Sokefun

August 2016

Genetic diversity analysis in South African taro (Colocasia esculenta) accessions using molecular tools

Taro [Colocasia esculenta (L) Schott] belongs to the family Araceae. It is an important staple food crop grown mainly by small scale farmers in many parts of the world. Taro is grown in South Africa from the coastal parts of the northern Eastern Cape to the KwaZulu-Natal north coast. Although it is an important staple in South Africa, very little information exists on the genetic diversity of the crop. Knowledge of the...

Author(s): Mwamba Nguluta, Patrick Adebola and Michael Pillay

August 2016

Comparison of Lagostomus maximus amelogenin gene (AMELX) with other mammals

The aim of this study was to compare the Lagostomus maximus AMEL sequence to assess their similarity with the AMEL genes from other mammals. Previously, a sequence of the AMEL gene of L. maximus which corresponds to the intron 3 of the human sequence for AMELX (AMEL on the X chromosome) was reported. The comparisons made, by the use of the algorithm provided by the NCBI (Basic Local Alignment Search Tool: BLAST) allowed...

Author(s): María Beatriz Espinosa

July 2016

Recurrent mutation in the HMGCL gene in a family segregating HMG-CoA lyase deficiency

The gene HMGCL encodes 3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) lyase. Mutations in HMG-CoA lyase cause HMG-CoA lyase deficiency (HMGCLD), which is an autosomal recessive congenital disorder of metabolism. This study was designed to detect mutation in the 3-hydroxy-3-methylglutaryl-CoA lyase (HMGCL) gene in a Saudi family segregating HMG-CoA lyase deficiency (HMGCLD).Methods: Clinical and molecular genetic analysis of a...

Author(s): Essa Alharby, Omhani Malibari, Hamad S. Al-Otaibi, Muhammad Saud, Ghadeer Al-Harbi, Mohammad I. Samman, and Sulman Basit

May 2016

Genotypic restriction patterns of finger millet (Eleusine coracana (l.) Gaertn) landraces in northern Nigeria

The present study was conducted to characterize the genetic diversity of 10 germplasm accessions of finger millet (Eleusine coracana (L) Gaertn) collected from diverse locations spread across the geographical zone of Northern Nigeria.  The digest was carried out using the molecular marker Restriction Fragment Digest (RFD on agarose gel while EcoR1 and Hind III restriction enzymes were used to cut the genomic DNA at...

Author(s): Umar I. D., Kwon-Ndung E. H. and Mailafia S.

January 2016

Association of the extracellular superoxide dismutase Ala40Thr polymorphism with type 2 diabetes mellitus and its complications in Lebanese population

Free radical-induced damage plays a significant role in the development of type 2 diabetes and its complications. Extracellular superoxide dismutase (EC-SOD) or SOD3 is one of the important scavenger enzymes that protects against oxidative damage and the formation of free radicals. EC-SOD is a copper- and zinc-containing secretory enzyme located in tissues and primarily in the extracellular matrix. EC-SOD has been...

Author(s): Nahed Saad, Mohamed E. Moustafa, and Hala A. Chamieh,

August 2015

DYS459, DYS391, DYS388 and DYS19 genetic loci have high allelic frequency in patients with prostate cancer

Prostate cancer is a significant disease in men, and a large number of individuals would benefit if risk factors that increase the susceptibility to develop prostate cancer could be established, which could aid in the early detection of the disease which is crucial for successful treatment. The first objective of this study was detection of allele frequencies of 12 Y-chromosome short tandem repeat loci from Iraqian...

Author(s): Hasanain Khaleel Shareef, Noran Jameel Ibraheem, Imad Hadi Hameed and Muhanned Abdulhasan Kareem

July 2015

Bael, Aegle marmelos (L.) Correa, an Indian medicinal plant protects V79 cells against the genotoxic effect of doxorubicin

Alleviation of doxorubicin (DOX)-induced cytotoxicity and genotoxicity by leaf extract of bael also known as Aegle marmelos (AME) was studied in cultured Chinese hamster V79 cells. The optimum protective dose of AME was determined by treating V79 cells with different concentrations of AME before exposure to 10 µg/ml DOX and then by evaluating the cell survival and micronuclei frequency in the cytokinesis blocked...

Author(s): Ganesh Chandra Jagetia and Ponemone Venkatesh

June 2015

Estimation of genetic parameters for first-lactation test-day milk yield in Holstein Friesian cows fitting random regression models

In this study, the effects of varying order of Legendre polynomials (LP) for permanent environmental (Pe) variance structure on the estimates of genetic parameters for first-lactation milk yield were evaluated fitting random regression (RR) test-day animal models. The total data set included 6850 test-day milk yield records from 800 first-lactation Holstein Friesian cows that calved between 1997 and 2013 and the...

Author(s): Meseret S., Tamir B. and Negussie E.

May 2015

Isolation and sequence analysis of a putative MerR-type-transcriptional regulator and a multidrug efflux protein of Bacillus circulans ATCC 21588: As potential targets of therapeutics

Mercury-type transcriptional regulators (MerR-transcriptional regulator) and major facilitator superfamily (MFS) transporters usually form an important sensor-response transport system in many microorganisms. This system has been shown to be involved in the regulation and transport (efflux) of a wide and diverse array of secondary metabolites including antimicrobial agents, dyes, chemicals, metals and evem harmful...

Author(s): Khaled Mohamed Anwar Aboshanab and Mostafa Mahmoud Elshafey

April 2015

Effects of cytokinin types and their concentration on in vitro shoot induction and multiplication of korarima

Korarima (Aframomum corrorima (Braun) P.C.M. Jansen) is a herbaceous perennial plant that belongs to the family Zingiberaceae in which lack of a steady supply of quality planting material is one of the bottlenecks for the exploitation of the export potential. Thus, the use of micropropagation is suggested to alleviate these problems. In micropropagation, in vitro seed germination and multiplication of hypocotyls/shoot...

Author(s): Rahiel Hagos and Hailay Gebremdhin      

February 2015

Evidence of over-dominance for sickle cell trait in a population sample from Buenaventura, Colombia

Sickle cell disease is a hereditary disease caused by a hemoglobin variant, known as hemoglobin S. This hemoglobin variant has a high frequency in areas where malaria is prevalent, because heterozygous genotype has a protective action against malaria infection. We evaluated evidence of over-dominance or deviation from Hardy- Weinberg equilibrium for the HbS gene in Buenaventura, an afro-descendent population with actual...

Author(s): Diana Carolina Ortega Cristian Fong, Heiber Cárdenas and Guillermo Barreto

November 2014

Multivariate analysis of genetic divergence among Ethiopian mustard (Brassica Carinata A. Braun) landraces in Ethiopia

Characterization of existing genetic variability is a prerequisite for further crop improvement activity. This study was designed to assess genetic variability among randomly selected Ethiopian mustard (Brassica Carinata A. Braun) genotypes from different agro ecology of Ethiopia. The present study was undertaken to determine nature of association of agronomic traits of 36 Ethiopian mustard (Brassica carinata) genotypes...

Author(s): Tesfaye Walle Mekonnen and Adugna Wakjira

November 2014

Genetic polymorphism of blood potassium in goat belonging to the different breeds in Mongolia

In goats belonging to the different breeds and sub breed, the genetic polymorphism at the determinant locus of blood potassium was revealed by flame spectrophotometer method. The kalemic systems in those breeds were characterized by a polymorphism of middle level due to the existence of the two phenotypes and of three genotypes. The polymorphic character of this system is given by the distributional discontinuity of...

Author(s): Myagmarsuren Purevdorj, Battsetseg Badgar, Dungu Dorjsuren and Myagmardulam Uherch

October 2014

Use of simple sequence repeat (SSR) markers to establish genetic relationships among cassava cultivars released by different research groups in Ghanaian

Cassava (Manihot esculenta) is an important staple crop widely cultivated in Ghana. The crop also has diverse industrial applications including starch, beer and alcohol productions. Knowledge about the state of the Ghanaian cassava genetic diversity and population structure is paramount in breeding programmes aimed at cultivar improvements or breeding of new cultivars for specific purposes. This study focused on the use...

Author(s): Peter Twumasi, Eric Warren Acquah, Marian D. Quain and Elizabeth Y. Parkes

March 2014

Heliclobacter pylori associated chronic gastritis: Endoscopic and pathological findings, comparative study

Helicobacter pylori have been established as a major etiologic factor in the pathogenesis of chronic gastritis, peptic ulcer disease and in the development of gastric adenocarcinoma and gastric mucosa-associated lymphoid tissue lymphoma. This study was conducted on 100 patients. All underwent upper endoscopy, and antral and corpus, and duodenal biopsies were taken. Findings of endoscopic gastritis were observed in 83...

Author(s): Awwad K. A. Alenezy and Taha M. M. Hassan

March 2014

Challenges in conserving and utilizing plant genetic resources (PGR)

The problems of food and income security are of global significance and are further compounded by precedential increase in world population resulting in overexploitation of natural resources and by extension plant genetic diversity. Plant genetic resources (PGR) refer to the heritable materials contained within and among plant species of present and potential value. In the recent past, genetic diversity found in...

Author(s): Ogwu, M. C., Osawaru, M. E. and Ahana, C. M.

January 2014

Partitioning and distribution of random amplified polymorphic DNA (RAPD) variation among eggplant Solanum L. in Southwest Nigeria

Solanum L., the largest genus of the Solanaceae family, vary morphologically, is diverse in number and is ecogeographically distributed. In Nigeria, previous studies had focused mainly on chromosome morphology, genome description and medicinal values, which are insufficient for genetic affinities. This study used four highly polymorphic random amplified polymorphic DNA primers to describe both the genetic relatedness...

Author(s): Sifau, Mutiu Oyekunle, Ogunkanmi, Liasu Adebayo, Adekoya, Khalid Olajide, Oboh, Bola Olufunmilayo and Ogundipe, Oluwatoyin Temitayo

January 2014

Variability assessment of seed traits in Jatropha curcas L. for improvement of oil yield

Jatropha curcas has received considerable attention from researchers as a potential source of non-edible vegetable oil which is eminently suitable for production of liquid bio fuel, meeting international standards. For any tree improvement and breeding programme, study of variation among the populations is prerequisite as it helps in the detection of relative performance of various traits of economic value. 28 candidate...

Author(s): Sanjeev Kumar and Sanjay Singh

December 2013

Insilico docking studies and evaluation of volatile oil of Zingiber officinale Rosc. and Aripiprazole for antidepressant activity

The objective of the study was to evaluate the volatile oil of Zingiber officinale Rosc. and Aripiprazole for antidepressant activity and to carry out the docking studies for their respective binding sites. Argus Lab 4.0.1 software (Mark A. Thompson, Planaria Software   LLC, and Seattle, WA, USA) was used to perform the docking studies and the elevated plus maze, forced swim...

Author(s): Sibi P. Ittiyavirah and Meera Paul

December 2013

Application of multiple displacement amplification in detection of five events of genetically modified organisms

In this study, multiple displacement amplification (MDA) was used for transgene detection, and proved to effectively improve the sensitivity of most fluorescence polymerase chain (PCR). Five events of genetically modified plants were chosen for detection in different plant species by MDA and real-time PCRs. Individual primer/probe systems based on each transgene target were used. The extracted DNA of each sample was...

Author(s): Xi Zhou, Hongwei Gao, Liqing Zhao, Wenda Liu, Min Sun and Shubai Wang

November 2013

Low genetic diversity of Hypophthalmus marginatus from the Tocantins River based on cytochrome b sequence data

  In this study, we used a portion of mitochondrial cytochrome b to evaluate the current genetic structure of the Hypophthalmus marginatus Valenciennes 1840, from the Tocantins River in the eastern Amazonia. Genetic diversity was measured in two downstream (Abaetetuba and Cametá), and two upstream (Tucuruí and Itupiranga) stocks under influence of the Tucuruí Hydroelectric Dam....

Author(s):   Emil José Hernández-Ruz, Evonnildo Costa Gonçalves, Artur Silva and Maria Paula Cruz Schneider

November 2013

Multivariate analysis of some Ethiopian field pea (Pisum sativum L.) genotypes

  The information on the nature and degree of diversity in the genotypes is crucial for efficient utilization of existing genetic resources. Thirteen (13) field pea genotypes along with two standard and one local checks were evaluated in triplicate randomized complete block design for three consecutive years to estimate the genetic variability and identify superior genotypes that generate putative transgressive...

Author(s): Seboka Habtamu and Fikreselassie Million

October 2013

Role of apoptosis-related factors in follicular atresia

Follicular atresia is the term used for the fate of follicles which undergo degenerative changes before rupturing during ovulation. Recent studies suggest that granulosa cell apoptosis play a major role in follicular atresia. The factors which lead the cell to apoptosis and which protect the cell death, still remain complicated and more studies are needed to elucidate the whole process. Here in this review, we aimed to...

Author(s): Basak Gumus, Sevtap Kilic and Ebru Zulfikaroglu

October 2013

Effects of organic insecticides, Kingbo and Azdar 10 EC, on mitotic chromosomes in root tip cells of Allium cepa

In this study, two organic insecticides (Kingbo and Azdar 10EC) extracted from plants and used as agricultural pesticides were investigated for cytotoxic and genotoxic effects using root tips of Allium cepa assay. Three different concentrations (0.625, 1.62 mL.L-1 and 2.5 mL.L-1) were used for different periods of time (8, 16 and 24 h). A single treatment of the effects of the two organic...

Author(s): Mona S. Al-Ahmadi

September 2013

Inheritance of primary yield component traits of common beans (Phaseolus Vulgaris L.): Number of seeds per pod and 1000 seed weight in an 8 × 8 diallel cross population

  Thirty six (36) genotypes (eight parents and 28 F1 diallel crosses) were grown in randomized complete block design with two replicates during 2006 at Mandura, North western Ethiopia. The experiment was executed to study the inheritance of two primary yield component traits: number of seeds per pod and 1000 seed weight. Statistical significant difference was observed between genotypes, parents and crosses for...

Author(s): Mulugeta Atnaf, Hussein Mohammed and Habtamu Zelleke

September 2013

Molecular characterization of cotton using simple sequence repeat (SSR) markers and application of genetic analysis

  Cotton is grown worldwide for the production of fiber and an important oil seed crop. Genetic diversity and correlation between varieties are of great importance for cotton breeding. To find out polymorphism and genome changeability, DNA markers are most comprehensively used. The current work was conducted to study the genetic relatedness among 20 cotton genotypes using simple sequence repeats markers using...

Author(s): Ambreen Ijaz, Sadia Ali, Usman Ijaz, Smiullah and Tayyaba Shaheen

August 2013

Two genotypes of Xanthomonas oryzae pv. oryzae virulence identified in West Africa

Bacterial leaf blight (BLB) caused by Xanthomonas oryzae pv. oryzae (Xoo), is a very destructive rice disease worldwide. The aim of the present study was to examine if the Xoo virulence pathotypes obtained using phenotypic pathotyping could be confirmed using molecular approach. After screening of 60 Operon primers with genomic DNA of two Xoo isolates (virulent pathotype, Vr and mildly virulent pathotype, MVr), 12...

Author(s): Onasanya Amos, M. M. Ekperigin, A. Afolabi, R. O. Onasanya, Abiodun A. Ojo and I. Ingelbrecht

August 2013

The genetic relatedness of drug resistant E.coli isolates of human and animal origin in Nigeria

Molecular epidemiology of human and animal ecovariants of Escherichia coli from different regions of Nigeria were studied using their antibiotic susceptibility patterns, plasmid profile and pulsed-field gel electrophoresis (PFGE). E. coli was isolated using eosin methylene blue agar (EMB) and identified by conventional microbiological technique. The isolates were tested against 14 antibiotics using the disc diffusion...

Author(s): Chijioke A. Nsofor, Christian U. Iroegbu, Douglas R. Call and Margaret A. Davies

April 2013

Karyotype and meiosis analysis of four species of Cameroonian Pyrgomorphidae (Orthoptera)

  In this article, the karyotypic features (chromosome number, morphology, size and length and length of X chromosome), and meiosis in Atractomorpha lata, Dictyophorus griseus,Taphronota thaelephora and Zonocerus variegatus (Orthoptera: Pyrgomorphidae: Pyrgomorphinae) were analysed in order to determine similarities and differences amongst them. All four species were...

Author(s): Seino Richard Akwanjoh, Dongmo Alain, Dongmo Tonleu and Manjeli Yacouba

April 2013

Interaction between angiotensin converting enzyme (ACE) insertion/deletion and aldosterone synthase (CYP11B2) -344C/T polymorphisms in relation to type 2 diabetes mellitus risk in Emiratis

  Polymorphism in Renin-Angiotensin-Aldosterone System (RAAS) genes have been studied extensively in various ethnic groups and largely with inconsistent findings on relationship with the risk of developing type 2 diabetes mellitus (T2DM). In this study, we investigated the association of Insertion/Deletion (I/D) polymorphism of angiotensin converting enzyme (ACE) and -344 C/T polymorphism of aldosterone...

Author(s): Habiba Al-Safar, Sarika S. Pillai, Luhaib Jalal Abood, Amrita Singh Chandhoke,Shahina K. Usman, Ahmed Hassoun and Naushad Rais

February 2013

Clinical features in a pediatric population due to chromosome deletions at a third level pediatric Mexican hospital in 19 years period of time: Five case reports

  Chromosome aberrations are considered as alterations in the chromosome number or structure. They are mainly due to gametogenesis inborn error (meiosis) or occur during the zygote first cellular divisions where DNA repair processes are deficient.  Two Wolf Syndrome patients and two criduchat patients or patients with deletion of the short arm of chromosome 4 and 5, respectively, and deletion of chromosome...

Author(s):   Aparicio-Rodríguez J. M., Hurtado-Hernández M. D. L., Barrientos-Pérez M., Zamudio-Meneses R., Palma-Guzmán M., Chavez-Ozeki H. and Chatelain-Mercado S.

February 2013

Genetic variability, heritability and correlation in some faba bean genotypes (Vicia faba L.) grown in Northwestern Ethiopia

  A study was conducted at Dabat, Northwestern Ethiopia, during 2010 cropping season. Genotypic and phenotypic coefficient of variation, heritability and correlation coefficients were performed for yield and its contributing parameters in 10 faba bean genotypes. Analysis of variance for traits studied showed significant (P<0.01) differences among the genotypes. Phenotypic coefficient of variation values for...

Author(s):   Tafere Mulualem, Tadesse Dessalegn and Yigzaw Dessalegn

November 2012

Acute myeloid leukaemia associated to chromosome 6: Clinical and phenotypical implications in two pediatric patients with chromosome trisomy and translocation

  Chromosome aberrations are considered alterations in the chromosome number or structure. They are mainly considered due to gametogenesis inborn error or during the zygote first cellular divisions. Among 4617 chromosomal studies performed during 19 years (from 1992 to 2011), at Hospital Para El Niño Poblano in México, 34.6% (1596 patients) had chromosomal alterations. Among these study...

Author(s):   Aparicio-Rodríguez J. M., Hurtado-Hernández M. L., Marroquín-García I., Rojas-Rivera G. A., Cuellar-López F., Cubillo-León M. A., Garrido-Hernández M. A.and Chatelain-Mercado S.

November 2012

Evaluation of genetic heterogeneity in glutamate carboxypeptidase II (H475Y) and reduced folate carrier (SLC19A1) gene variants increased risk factor for the development of neural tube defects in eastern region of India

In humans, neural tube failure to close during the 4th week of gestation leads to the development of severe congenital malformations of the central nervous system because of an error in maternal folate metabolism associated gene variants. The frequency of genotypic variants of GCP II (H475Y) and folate carrier RFCI (SLC19A1) gene polymorphism (80 G →A) were evaluated as potential candidate gene(s) and also assess...

Author(s): Ajit Kumar Saxena, S. Pandey and L. K. Pandey

December 2011

Uraemic neuropathy: A review

  Uraemic neuropathy is an increasingly common condition, it is therefore important to understand its pathophysiology as well as its clinical manifestations. The objective of this study is to make a clear diagnostic approach and to provide treatment following the patient’s condition.   Key words: Uraemia, dialysis, renal transplantation, kidney failure, chronic kidney disease (CKD)

Author(s): Basilio Vagner Ramírez, and Paula Andrea Bustamante Gómez

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