Journal of
Pharmacognosy and Phytotherapy

  • Abbreviation: J. Pharmacognosy Phytother.
  • Language: English
  • ISSN: 2141-2502
  • DOI: 10.5897/JPP
  • Start Year: 2009

JPP Articles in press

Anti-atherosclerosis effect of the 3,4-Dihydroxybenzaldehyde Screening from Gastrodia elata Blume

Article in Press

Gastrodia elata Blume (GEB) is a traditional Chinese medicine used to treat central nervous system diseases and related conditions. Previous studies implicated GEB has a protective effect in Atherosclerosis (AS), and that the underlying mechanism is related to anti-platelet hyperactivity. The present study investigated the potential protective effects and mechanisms of a phenolic component, 3,4-Dihydroxybenzaldehyde...

Author(s):Jianjun Cheng, Jubeng Yang, Chun Xiao, Falong Nie, Fangyan He, Jin Yu, Xiufang Li,Rong Dai

Epidemiological status of coronavirus diseases and the potentials of remedy with medicinal plants in Africa

Article in Press

This review aimed at exploring the epidemiological status of coronavirus disease (COVID-19) and assemblage of various plant species that have prophylactic or therapeutic potentials on the disease. Epidemiological data were obtained from various health authorities worldwide and articles published in standard journals from 2002-2020 totaling 103 on medicinal plants used in treating the disease and similar diseases....

Author(s):Lateef Ariyo Adeniran, Emmanuel Segun Oguntade and Toba Samuel Anjorin

Bee propolis: production optimization and applications in Nigeria

Article in Press

Propolis is a resinous substance produced by bees with a wide range of medicinal uses. It is collected by bees from buds, leaves and bark exudates of several plants in both tropical and temperate regions. Propolis is sometimes referred to as “bee glue” as it is produced by bees for sealing and protection of their hives. Exploration and research into propolis and its biologically active constituents is increasing. Bee...

Author(s):Okhale SE, Nkwegu C, Ugbabe GE, Ibrahim JA, Egharevba HO, Kunle OF, Igoli JO

Green Synthesis of Silver Nanoparticles through Reduction with Euphorbia nivulia Buch.-Ham., stem bark extract: Characterization and Antimicrobial Activity

Article in Press

Nanoparticles, because of their diversified applications in the field of modern medicine gained lot of importance thrust area. In the present investigation, synthesis and characterization of Silver nanoparticles (AgNPs) and their antimicrobial effect on certain pathogenic bacteria were studied. AgNPs were prepared by green synthesis process using stem extract of Euphorbia nivulia, from 1mM AgNO3 solution. The color...

Author(s):Naidu Sarojini Devi, Y. Padma and R.R. Venkata Raju

Screening of Potential Antioxidant with Inhibition of Free Radicals from the Extract Seluang Belum Roots (Luvunga sarmentosa (Blume) Kurz.) by ABTS Assay

Article in Press

An unhealthy lifestyle will usually cause free radical compounds that are reactive against cells and tissues of the body. Therefore free radical reactions in the body can be muted with the use of antioxidants that can help protect the body from free radical attack and resist its negative impact. The synthetic antioxidants such as BHA and BHT can cause damage to the liver and carcinogenic. Some scientific studies around the...

Author(s):Elsa Trinovita

Comparative studies on bioactive constituents of methanol extract of Picralima nitida : A medicinal plant frequently used in South-eastern Nigerian folk medicine

Article in Press

Picralima nitida is a medicinal plant of the family Apocynaceae, frequently used in South- eastern Nigerian traditional medicine for its therapeutic properties. This study is a comparative evaluation on the chemical constituents and bioactivity of Picralima nitida seed, leaf, root and stem back methanol extracts. The phytoconstituents present were identified using GC-MS (Gas Chromatography-Mass Spectrometry) analysis. The...


Hepatoprotective potential of Blepharis persica (burm. f.) o. kuntze.

Article in Press

This study aimed to assess the hepatoprotective activity of ethanol (90%) extract of Blepharis persica seeds (BPEE) in rats. The plant extract showed a remarkable hepatoprotective activity against acetaminophen-induced hepatotoxicity as judged from the serum marker enzymes and histopathological studies on liver tissues. The acetaminophen-induced group shows a significant rise in the serum enzymes. Treatment of rats with...

Author(s):Vichitra Kaushik, Gagandeep Chaudhary, Shoaib Ahmad, Vipin Saini, A. Pandurangan, Manish Kumar and G. Arunachalam

Characterization of the chemical composition of Lippia alba Mill. essential oil in the dry and rainy seasons

Article in Press

Lippia alba is a native species popularly known as "lemon balm", used in folk medicine for the treatment of several diseases. This work aims to study the ethnobotany of L. alba and to determine the chemical composition of essential oils from the fresh leaves of L. alba during both rainy and dry seasons. The volatile contents of the oil samples were determined by Gas Chromatography coupled to Mass Spectrometry - GC/MS. The...

Author(s):Rodrigo Dias Alves, Ianara Mendonça da Costa, Francisca Overlânia Vieira lima, Luciana Cristina Borges Fernandes, Dinalva Brito de Queiroz, Eduardo Pereira de Azevedoc, Jacqueline do Carmo Barreto and Fausto Pierdoná Guzen

Medicinal Value of the Seed Essential Oil of Eucalyptus citriodora Hook

Article in Press

Eucalyptus essential oil is an important aroma-therapeutic agent in the treatment of diverse diseases and ailments in human and animals. The aim of this study was to determine the composition and pharmacological properties of the seed essential oil of E. citriodora from Nigeria. The essential oil was extracted by hydro-distillation using Clevenger-type apparatus and analyzed using GC-MS. The total phenolic content,...

Author(s):Ololade, Z.S. and Olawore, N.O.

Acute and subchronic toxicity assessment of Melastomastrum capitatum Fern. leaf methanol extract in Wistar albino rats

Article in Press

This study was carried in order to determine short-term (acute) and long-term(subchronic) effects of Melastomastrum capitatum leaf methanol extract in the management and treatment of certain diseases in traditional and complementary medicines by many villages in Mambila Nigeria. Acute and subchronic toxicities were carried out in accordance with the Organization for Economic Cooperation and Development (OECD) guidelines....

Author(s):Cletus Anes Ukwubile, Abubakar Ahmed, Umar Adamu Katsayal, Jamilu Ya'u and Henry I. Nettey


Article in Press

The roots of Chasmanthera dependens were studied to determine their active constituents and antimicrobial activity. A phytochemical investigation of C. dependens using chloroform and methanol extracts led to the isolation and identification of the following secondary metabolites; alkaloids, flavonoids, tannins, phenolics, carbohydrates, reducing sugars, terpenoids, steroids, saponins. The antimicrobial activities of these...

Author(s):Anosike, Chioma Assumpta., Nwachukwu, Justus Nmaduka, Ogbozor, Chinedu. Samuel and Madueke, Chidi Augustine.


Article in Press

Objective: To study detailed Pharmacognostic profile and preliminary phytochemical investigation of the leaves of Indigofera tinctoria Linn. commonly known as ‘indigo’ belongs to the family Fabaceae. It is distributed through the hotter parts of India. Medicinal uses include the juice of the leaves as a prophylactic against hydrophobia, and as a decoction for blennorrhagia; plant extract as the treatment for epilepsy,...

Author(s):Dhanapal Venkatachalam


Article in Press

Objectives: This study covers the microscopic studies, the phytochemical screening, acute toxicity evaluation and anti-inflammatory activity of the methanol extract of the leaves of Sabiceabrevipes. This plant has not been studied extensively; even when such studies were done; the focus was on the root rather than the leaf, which is easier to harvest and more abundant. Method: Free hand sections were used for anatomical...

Author(s):Michel Kenne Tchimene, Sunday Patrick Gaza Anze, Christopher Obodike Ezugwu and Maurice Mmaduakolam Iwu

Comparative Proximate Composition and Hypoglycemic Properties of Three Medicinal Plants (Verononiaamygdalina, AzadirachtaindicaandMoringaoleifera).

Article in Press

The present study sought to investigate proximate composition in relation to the short and long term hypoglycemic effects of ethanol/water extracts of Verononiaamygdalina, AzadirachtaindicaandMoringaoleifera on hyperglycemic rats. Hyperglycemia was induced by single intra-peritoneal injection of 0.1 mol/L alloxan monohydrate in citrate buffer (pH = 4.5); dosage = 140 mg/kg; b/w.Hyperglycemic rats received separate dose of...

Author(s):Chikezie P.C and Ojiko O.A

Anti-inflammatory and antioxidant activity of Ixora coccinea stems

Article in Press

Background and objective: Ixora coccinea has mentioned in Ayurveda as Paranti and traditionally stems used in inflammatory diseases like sprains, eczema, contusions and boils. Present study deals with assessment of anti-inflammatory and antioxidant activity of extracts of I. coccinea stem. Methodology: Anti-inflammatory activity was accessed by in vivo carrageenan-induced paw edema in rat and in vitro human red blood...

Author(s):Ajaykumar Rikhabchand Surana and Rajendra Dayaram Wagh


Article in Press

Tea and coffee have been consumed for hundreds of years for their flavour and stimulating properties. Nowadays, caffeine is receiving an increasing interest in food and pharmaceutical industries due to its central nervous system CNS stimulating properties, peripheral vasoconstriction, relaxation of the smooth muscle and myocardial stimulation. Caffeine constitutes an average of 4% of tea leaf and 1.5% of coffee bean. The...

Author(s):Hattem Mohamed Mekky


Article in Press

Diabetes mellitus is a metabolic disorder in the endocrine system. This dreadful disease is found in all parts of the world and is becoming a serious threat to mankind health. There are lots of chemical agents available to control and to treat diabetic patients, but total recovery from diabetes has not been reported up to this date. Alternative to these synthetic agents, plants provide a potential source of hypoglycemic...

Author(s):Maninder Kaur

Fungal metagenomes in polyherbal medicines used for the treatment of tuberculosis

Article in Press

The traditional systems of medicine have significantly become more accepted in the developed and developing countries due to their curative property, less toxicity and minimal side effects. However, several studies have shown that they are associated with microbial contaminants. This study aimed at identifying fungi in nine polyherbal medicines used for the treatment of tuberculosis in Eastern Cape Province, South Africa....

Author(s):Elizabeth Bosede Famewo, Anna Maria Clarke and Anthony Jide Afolayan

Antimicrobial activity of leaf and flower extracts of Ocimum gratissimum on selected microorganisms

Article in Press

The antimicrobial activities of flower and leaf extract of Ocimum gratissimum obtained from the garden of the Faculty of Pharmacy and Pharmaceutical Sciences, Kwame Nkrumah University of Science and Technology Ghana, was tested against Staphylococcus aureus, Bacillus subtilis (Gram positive bacteria), Klebsiella pneumonia, Pseudomonas aeruginosa, Escherichia coli (Gram negative bacteria) and Candida albicans (fungi). These...

Author(s):Aryee Feizel Ayitey

Development of Validated High performance thin layer chromatography method for simultaneous determination of quercetin and kaempferol in Thespesia populnea

Article in Press

Thespesia populnea L. (Family: Malvaceae) is a well-known medicinal plant distributed in tropical regions of world and cultivated in south Gujarat and indicated to be useful in cutaneous affections, psoriasis, ringworm and eczema. Bark and fruits are indicated in the diseases of skin, urethritis and gonorrhea. The juice of fruits is employed in treating certain hepatic diseases. The plant is reported to contain flavanoids,...

Author(s):Hiteksha Panchal, Aeshna Amin and Mamta Shah

Potential of Kelakai plants (Stenochlaena palustris (Burm.F.) Bedd.) from Central Kalimantan as aphrodisiac

Article in Press

The necessity for traditional medicine is efficacious as aphrodisiac increases every year. Dayak community believes that Kelakai roots have efficacy as an aphrodisiac drug, but no studies were conducted relating to the efficacy of the Kelakai roots.Traditional medicinal products are efficacious as aphrodisiac have a hormone-like effect, usually contain active ingredients that have estrogenic properties among other things...

Author(s):Fahruni, Rezqi Handayani and Susi Novaryatiin


Article in Press

Garcinia hanburyi belongs to the family Clusiaceae. The whole plant was dried, extracted to obtain Xanthone rich extract. Phytochemical studies of extract showed the presence of Phenols, Alkaloids, steroids, resins and saponins. The natural sources such as a plants are an abundant source having various medicinal properties. In the present study, Garcinia hanburyi has been selected to test for the Anti-inflammatory activity...

Author(s):J. Narayanan and V.CHITRA

Biochemical and antibacterial activity of Jojoba Oil ‘Simmondsia chinensis’ in rats

Article in Press

This study has evaluated the antibacterial effect of Jojoba oil (J.O) in vivo against Staphylococcus aureus. One hundred mature male Sprague Dawley rats were divided into four groups, including the control groups and the groups treated with J.O. as part of the diet mixture (2.5% of total body weight). Our findings suggest a significant increase in body weight gain (94.0 ±5.404 g for J.O treated rats in comparison to 72.0...

Author(s):Shahd Abuhelal

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