Chlorine dioxide treatment for diabetic foot ulcers: Three case studies
November 2024
Foot ulcers are a major source of morbidity and mortality for individuals suffering from diabetes mellitus. Currently, available treatments for these wounds are often ineffective, which can lead to the progression of these lesions to a point that requires amputation of the affected limb. Despite amputation, these individuals subsequently suffer from an increased risk of mortality. A novel therapy has been suggested to...
Assessment of the practice of exposing infants to sunlight and associated factors among caregivers attending Asella Teaching and Referral Hospital, Southeast Ethiopia
October 2024
This study is an overview of a previous study conducted in Debre Berhan town in 2021, which highlighted that a significant percentage of participants had poor practice in sunlight exposure for infants. It mentions that mothers, particularly housewives or government employees aged 33 and above, believe that sunlight strengthens infant bones and improves their health. Additionally, it states that mothers who received...
Pathophysiology of spinal cord injury and potential health benefits of omega-3 fatty acid
April 2024
Spinal cord injury (SCI), is a life changing threatening neurological condition that completely changes patients’ life. It has been shown that early treatment soon after the injury may improve neurological recovery. To date, no therapeutic modalities exist that have shown very positive effect on neurological outcomes. However, recent clinical and preclinical studies have shown little hope for the treatment of SCI....
Chlorine dioxide and chlorite as treatments for diabetic foot ulcers
March 2024
The global prevalence of diabetes mellitus is rising and is predicted to exceed 10% by 2030. Foot ulcers are a frequent complication of diabetes mellitus. Existing treatments for diabetic foot ulcers are only partially effective and when these ulcers do not heal, amputation of the affected limb may result. It is estimated that an amputation due to diabetic foot infection occurs every 30 seconds somewhere in the...
Awareness of cervical cancer screening services and uptake of free liquid-based cytology test among brothel-based female sex workers in Sokoto State, Nigeria
May 2023
There are few studies on the awareness and uptake of cervical cancer (Ca Cervix) screening services among Female Sex Workers (FSWs) in Nigeria despite the increased risk of Ca Cervix among FSWs and the potential benefit of early screening. The study aimed to assess the awareness, uptake, barriers to and predictors of uptake of Ca Cervix screening services among FSWs. A cross-sectional analytical study was conducted...
Anatomical figures obtained by means of a delineation technique as an additional strategy in the clinical evaluation of the thyroid
May 2023
In patients with morphological alterations of the thyroid, both the physical examination (inspection and palpation) and the imaging studies continue to be the cornerstone for their evaluation, treatment, and long-term follow-up. The realization of anatomical figures, obtained by means of a thyroid morphology delineation technique, is proposed as an additional exploratory intervention strategy in the initial clinical...
Bacterial load reduction efficacy, acceptability and cost benefit of a locally produced Hand sanitizer in a tertiary Hospital in Uyo, Nigeria
July 2022
Local production of hand hygiene products result in increased availability and compliance with hand hygiene in healthcare settings and significant cost saving to hospitals if effective and acceptable. The aim of this study was to compare the effectiveness, acceptability, and cost benefit of a locally produced hand sanitizer to commercial hand sanitizer products. This was a comparative cross sectional study carried out...
Accessibility to and utilization of maternal, neonatal and child health (MNCH) services by rural women: A case study of health centres in Mutare district based on the 3 delays model
July 2022
High maternal, neonatal and child mortality rate constituting about 70% of the population in Zimbabwe. Zimbabwean rural women have faced challenges in accessing and utilizing Maternal, Neonatal and Child Health (MNCH) services. Rural areas in Zimbabwe have had high prevalence of home deliveries and pregnancy related complications associated with lack of access to and utilization of MNCH services, resulting in high...
In-vitro antioxidant potential of conventional herbal decoction aiding diabetes metabolomics
June 2022
Diabetes mellitus (DM) is a risk factor of oxidative stress through the production of reactive oxygen species (ROS). ROS triggers cell damage which enhances the risk of several diabetes associated disorders such as neuropathy. There are many treatment options but no cure, and the quest for the natural, cost-effective treatment regimen is ongoing. Therefore, the present study was conducted to observe the in-vitro...
Assessment of recurrently diagnosed diseases dynamism at Korhogo General Hospital in Northern Côte d’Ivoire from 2014 to 2018.
March 2022
Because of, well established relationship between seasonal variability and diseases dynamism we embarked here in evaluating recurrently diagnosed diseases dynamism at Korhogo General Hospital in Northern Côte d’Ivoire from 2014 to 2018. For this purpose, clinical data with regard 1707 patients were collected and clusterized in 25 diseases cases. Data have been submitted to multivariate and computational...
Antimicrobial susceptibility patterns of Staphylococcus aureus in a tertiary referral hospital in Nairobi, Kenya
November 2021
Staphylococcus aureus is a leading cause of hospital and community acquired infections globally. Methicillin-resistant S. aureus (MRSA) prevalence has been reported to be high in various settings and is associated with increased morbidity, mortality and risk of nosocomial outbreaks. Surveillance of prevalence and antibiotic susceptibility patterns is important to ensure appropriate antibiotic prescription. The objective...
The chlorine dioxide controversy: A deadly poison or a cure for COVID-19?
September 2021
Chlorine dioxide has been condemned as a dangerous poison and has been touted as a cure for COVID-19. This narrative review examines the controversy surrounding the use of aqueous chlorine dioxide by investigating evidence-based research articles, government documents, press reports, and the results of the first clinical trial utilizing chlorine dioxide as a treatment for COVID-19. Chlorine dioxide was found to be...
Prevalence and risk factors of Hepatitis B virus infection among blood donors in Gabonese National Blood Transfusion Center: A cross-sectional and analytic study
June 2021
Hepatitis B virus (HBV) infection is prevalent in Gabon and poses a potential risk of transmission by blood transfusion. However, few studies have examined epidemiological data regarding HBV infection of Gabonese blood donors. This article reports on research conducted to estimate the seroprevalence of HBV and associated risk factors in the urban population of Gabon. A cross-sectional and analytic study survey of blood...
Day case tonsillectomy: A 9 year experience in Delta State Nigeria
May 2021
Tonsillectomy has generally been regarded as an in-patient procedure. Presently though, due to rising costs and space constraints, it has increasingly became popular as a day case procedure world-wide. However, careful selection of patients is advised so as to avoid undue risks and possible resulting mortalities. To find out the suitability or otherwise of day case tonsillectomies in a resource poor country, taking note...
Assessment of renal function tests, serum total protein, and lipid profile concentrations among pregnancy-induced hypertension attending women in Asrade Zewudie Memorable Hospital (ASZMPH), Gojjam, Ethiopia: Case-control study
November 2020
Pregnancy-induced hypertension has remained a significant cause of prenatal morbidity and mortality of mothers. So this study aims to assess renal function test, serum total protein, and lipid profile concentrations among pregnancy-induced hypertension women in Asrade Zewudie Memorable hospital (ASZMPH), Gojjam, Ethiopia. A case-control study was done on 200 pregnant women: 100 with pregnancy-induced hypertension (case...
Demographic and clinical determinants of multi drug resistant tuberculosis among HIV infected patients in Tanzania
September 2020
Multi Drug Resistant Tuberculosis (MDR-TB) is a public health challenge, which itself remains a global public health problem. Its impact is worsened by co-infection with Human immunodeficiency virus (HIV). In order to institute successful TB control strategies, factors for development of MDR-TB must be understood. This study aimed to identify and describe clinical and demographic determinants for development of MDR-TB...
The value of exercise therapy to asthmatic patients as an adjunct treatment
June 2020
Asthma is a chronic respiratory disease that adversely influences the quality of life of many South Africans. The medical management of asthma includes identification, education, medical and pharmaceutical treatment. Literature has inequitably demonstrated that habitual structured exercise therapy can be a beneficial adjunct to general medical and pharmaceutical management strategies. This clinical commentary aims to...
Information and communication technologies and patient empowerment: A complex skein
April 2020
This article aims to explore the relationship between patient empowerment and information and communication technologies (ICTs). Indeed, ICTs are considered important for increasing access to medical information and for patients’ other experiences, thereby nourishing the empowering rhetoric. The paper presents a research study conducted in Italy that focuses on the self-assessments made by online health...
Cause specific and trends of mortality in Nigeria: A six-year study of a tertiary hospital
January 2020
Mortality data necessary for proper healthcare planning, policy formulation, and implementation is hampered by a decline in hospital autopsy practice. Therefore, non-autopsy based death profile reviews provide a framework for the presentation and discussion of reliable mortality data. This study aims to present the general mortality profile of the University of Port Harcourt Teaching Hospital, Rivers State, Nigeria....
Arousal perception/misperception and total sleep time misperception in subjects with sleep disorders
May 2019
Limited studies have examined arousal perception in obstructive sleep apnea (OSA) or other sleep disorders. The aim of this study is to evaluate the factors that affect patients’ arousal and total sleep time perception. This is a retrospective study of 210 subjects divided into 5 groups: Primary insomnia; upper airway resistance syndrome (UARS)/primary snoring; mild, moderate and severe OSA. Perceived arousals...
Common ultramarathon trail running injuries and illnesses: A review (2007-2016)
April 2019
Regardless of the significant growth of ultra-marathon trail-running races over the last 40 years, epidemiological research is lacking. Presently, no review paper exists that integrates the empirical surveillances of ultra-marathon trail runners’ injuries and illnesses. The purpose of this work is to integrate the empirical findings of injuries and illness among trail runners during the period 2007-2016. An...
Correlates and self-management strategies of premenstrual dysphoric disorder (PMDD) among nursing students in a Nigerian teaching hospital
March 2019
Premenstrual dysphoric disorder (PMDD) is a severe premenstrual disorder characterized by distressing symptoms and significant impairments in personal, social and professional functioning. The study aimed to determine the magnitude of Premenstrual syndrome (PMS) and PMDD among nursing students of Usmanu Danfodiyo University Teaching Hospital (UDUTH) Sokoto State, Nigeria. A cross-sectional survey of 135 consenting...
Assessment of the trend and risk factors of under-five diarrhea morbidity and mortality in two selected communities in the West-Mamprusi District
March 2019
Diarrhea episodes among children under five years with its devastating consequences have been a concern to stakeholders in child survival strategy programs. Mothers are key in the prevention of diarrhea among children since they are the care givers. The main aim of this paper is to assess the trend and risk factors of under-five diarrheal disease in the study areas. Descriptive research design was employed for the...
Prevalence of preoperative hypertension and its intraoperative anesthetic management among patients undergoing elective surgery at Hawassa University Comprehensive Specialized Hospital, Southern Ethiopia
February 2019
Overall, twenty of the world’s adult populations live with hypertension. Blood pressure determination forms an integral part of anesthesiologist’s evaluation of the patient prior to and during surgery. 25% of surgical patients have hypertension preoperatively. There are several risks related to untreated preoperative hypertension in perioperative and postoperative phase. The objective of this study was to...
Prevalence and risk factors of acute backache after spinal anesthesia in surgical procedures at Asella Teaching and Referal Hospital, Asella, Ethiopia
January 2019
Spinal anesthesia is one of the routinely anesthetic procedures done in practice. Post spinal backache is one of the complications causing discomfort in patients, leading to rejection of its use for next operations. The aim of this work is to assess the prevalence and factors associated with backache after spinal anesthesia from October to January at Asella Teaching and Referral Hospital, Asella, Ethiopia, 2016....
Cystatin C protection of human umbilical vein endothelial cell against oxidative stress injury through activating autophagy
December 2018
Cystatin C (CysC)-induced autophagy may play a beneficial role in preventing subarachnoid hemorrhage-induced cerebral vasospasm. The role of CysC in endothelial cells (ECs) autophagy is unknown. This study explores the role of CysC during the process of oxidative stress in human umbilical vein endothelial cells (HUVECs). Oxidized LDL (oxLDL) was used to stimulate HUVECs in vitro study. The lactate dehydrogenase (LDH)...
Updating traumatic optic neuropathy
November 2018
Traumatic optic neuropathy (TON) is the affectation of the visual function, secondary to a damage caused by a direct or indirect traumatic mechanism over the optic nerve. It occurs in approximately 0.5 to 5% of closed head injuries, and in 2.5% of patients with maxillofacial trauma and mid-face fractures. The types of TON are direct, anterior indirect, posterior indirect, and chiasmal. This work aims to offer an...
Collodiaphyseal angle in the diagnosis of coxa vara and coxa valga in adult Nigerans
September 2018
Collodiaphyseal angle (CDA) is the angle formed between the femoral neck axis and the diaphysis axis. The aims of this study were to determine the normal range of collodiaphyseal angle in adults and to determine any difference in the collodiaphyseal angle between right and left femur and also between sexes. 340 subjects consisting of 170 (50%) males and 170 (50%) females were included in this study. Plain radiographs...
Diagnostic accuracy of ultrasound scans for the diagnosis of pelvic inflammatory disease keeping laboratory high vaginal swab/urine microscopy culture as gold standard in Anambra State, Nigeria
August 2018
Ultrasound scanning (USS) and high vaginal swab culture and urine microscopy culture and sensitivity (m/c/s) tests are the most common investigations used for the diagnosis of pelvic inflammatory disease (PID) in our locality. The aim of this study was to determine the diagnostic accuracy of ultrasound in the diagnosis of PID keeping laboratory high vaginal swab/urine microscopy, culture as gold standard. The USS, high...
Polycystic ovary syndrome: Impact of obesity and aging on the profile of gonadotrophin and adrenal hormones
July 2018
Many studies have been conducted to understand thoroughly the mechanism of polycystic ovaries syndrome (PCOS), but very few of them came from Africa. The aim of this study, was firstly to make a diagnostic of this syndrome, according to Rotterdam criteria, and secondly to assess the correlation of obesity and age on this pathology. The study was conducted at Bouaké, within the medical School and Hospital, during...
Factors associated with atherogenic dyslipidemia among hypertensive patients at southern Ethiopia
July 2018
Atherogenic dyslipidemia worsens cardiovascular functions and supporting data concerning dyslipidemia among hypertensive patients in Ethiopian situation is very limited. The objective of this study was to assess factors associated with atherogenic dyslipidemia among hypertensive patients at Southern Ethiopia. A cross-sectional study was conducted on 238 hypertensive participants at Hawassa University comprehensive...
Knowledge, attitude and practice of medical students towards complementary and alternate medicine
June 2018
Complementary and alternative medicine has been an important part of Pakistani culture for a long time. Whilst it is widely practiced amongst the general population, this study aims to determine attitude and practices of medical students towards complementary and alternative medicine (CAM), and their willingness to learn about them and give advice to their patients about it in future. Cross sectional study was conducted...
Emerging trends in the profession of Biokinetics: A 10 year perspective (2007-2017)
June 2018
The consistent review of developing patterns in any healthcare profession is important, as this allows the determination of whether the current practitioner registry meets the healthcare demands, or whether the patient market has become oversaturated with practitioners. The South African Biokinetics profession has been established for 35 years, but as never undergone an examination of its developing trends. The aim was...
Prevalence of thyroid cancer among thyroid swelling in Jimma University Medical Center, South West Ethiopia: A five-year retrospective study
May 2018
Thyroid cancer is the most common endocrine malignancies. It is postulated that goiter is a precursor lesion to the development of thyroid cancer. The worldwide prevalence of goiter in the general population is estimated at 4 to 7%. The objective of the study was to assess the burden of thyroid cancer among patients who visited Jimma University Medical Center (JUMC) with thyroid swelling over the past 5 years. The...
Antibiotics prescribing patterns and incidence of respiratory tract infection in children under five years: A study in two hospitals in Accra, Ghana
April 2018
Respiratory tract infections are known to have the highest incidence and mortality rates especially among children in developing countries. Antibiotic use is common in respiratory tract infections (RTI); however, increased rates of antibiotic resistance development have prompted studies on prescribing patterns and recommendations for appropriate antibiotic use. This study aims at monitoring prescription patterns of...
People healed of Ebola and their psychosocial life: About 55 cases at the Donka treatment center (Conakry)
March 2018
Ebola virus disease (EVD), formerly known as Ebola hemorrhagic fever (EHF), is often a severe and fatal disease. The objective of this study is to identify the psychological and social problems as well as the needs of people cured of Ebola. This work is a prospective, cross-sectional, descriptive study done within a period of three months, from 16 November 2014 to 15 February 2015. The population of this research...
Assessment of influence of student perception, knowledge, and area of specilization on ICT utilization for academic purposes in College of Health Technology, Calabar
March 2018
Information Communication Technology (ICT) application in academics and research has come to stay. While the developed world has not only embraced ICT in academics, they have gone ahead to make teaching and learning far more simpler, on the other hand most of the developed world is still grappling with the provision of basic amenities to its citizens that the idea of ICT appears farfetched and elitist. This study was...
Auditory effects of noise and its prevalence among sawmill workers
February 2018
Noise at work could be hazardous, particularly after prolonged period of exposure. Sources of noise include generators, grinding machines, loud music at home, religious houses and clubs. The objective of this study was to find the auditory effects of noise and its effects on sawmill workers. This is a prospective, community based study involving sawmill workers in Ile-Ife. The prevalence of hearing loss was...
Profile and management of community acquired pneumonia in a tertiary care hospital in Karachi
February 2018
The objective of this study was to assess the demographic profile, severity of patient, co morbidity, length of stay (LOS) and management of community acquired pneumonia. The study was a prospective study and consist of 212 patients (>20 years of age) with community acquired pneumonia (CAP) hospitalized to the tertiary care hospital, situated in Karachi between 1st January, 2010 and 31st March, 2012. Information...
Determination, knowledge and prevalence of pregnancy-induced hypertension/eclampsia among women of childbearing age at Same District Hospital in Tanzania
February 2018
Several risk factors including hypertension are common complications of pregnancy with preeclampsia particularly associated with substantial risk to both the mother and fetus. This cross-sectional study involving quantitative approach was conducted in Same District Hospital in Tanzania. Data were collected from all pregnant women in the hospital using questionnaires. Respondents’ knowledge on maternal mortality...
Health service delivery in selected municipalities in Leyte: Inputs for improved health service delivery
January 2018
Utilizing descriptive research design, this study investigated the nature and implementation extent of service delivery related to reproductive health (RH) and tuberculosis (TB) control. Data were gathered using existing data files, survey checklist questionnaires and interview schedule. The questionnaires were pilot-tested then implemented on actual respondents. Findings showed there was adequate number of needed...
The value of C–reactive protein in the diagnosis of septicaemia in children with malaria
January 2018
Malaria and septicaemia, both major causes of infant and early childhood morbidity and mortality in Nigeria, often co-exist and are difficult to differentiate. This study was designed to test the hypothesis that C-reactive protein (CRP) levels could differentiate between malaria and malaria coexisting with septicaemia. One hundred and fifty-one children aged 6 to 60 months with fever without localising signs and 141...
Descriptive analysis of neoplasias diagnosed as pleomorphic adenoma (PA) that presented at the University of Nigeria Teaching Hospital Ituku-Ozalla Enugu
January 2018
Pleomorphic adenoma of the salivary gland is described as a slow growing painless benign tumor characterized histologically by its mixed appearance with epithelial and myoepithelial components. It occurs in both the major and minor salivary glands with the parotid gland as the commonest site for the major gland while the palate is the commonest site for the minor glands. This study was conducted to evaluate the clinical...
External application of moisture exposed burn ointment for phlebitis: A meta-analysis of randomized controlled trials
December 2017
To evaluate the therapeutic effects of moisture exposed burn ointment (MEBO) on phlebitis, seven electronic databases where checked until September, 2016 for randomized controlled trials (RCTs) of MEBO on phlebitis. Risk of bias was assessed using Cochrane handbook guidelines. Thirty eight randomized controlled trials met the inclusion criteria in which the aggregated results indicated that comparison revealed...
Assessment of breast self-examination practice and associated factors among female health professionals in Western Ethiopia: A cross sectional study
December 2017
Breast cancer is the leading cause of cancer mortality worldwide. Breast cancer incidence is increasing both in developed and developing regions. Regular breast self-examination (BSE) is one of the most cost effective methods for early detection of breast cancer in asymptomatic women. The aim of this study is to assess the magnitude of BSE practice and its associated factors among female health professionals working in...
Is moist exposed burn ointment effective for diabetic foot ulcers? A meta-analysis of randomized controlled trials
December 2017
This meta-analysis aimed to assess the effectiveness of moist exposed burn ointment (MEBO) for diabetic foot ulcers (DFU). Two researchers independently assessed the quality and validity of included randomized controlled trials (RCTs) in 7 electronic databases. Risk of bias was assessed using Cochrane handbook guidelines. Twenty seven trials which include 1,979 patients were involved for analysis. Comparison of the same...
Assessments of health professionals’ knowledge towards post-operative pain management in Asella Teaching and Referral Hospital, South East Ethiopia
November 2017
Pain is defined as any an unpleasant sensory and emotional experience associated with actual or potential tissue damage. Adequate postoperative pain management can reduce the patients‟ length of hospitalization and decrease postoperative complications. However, post-operative pain has not been satisfactorily relieved. Thus, the aim of this work is to assess professionals’ knowledge on post-operative pain...
Assessment of respiratory status among workers exposed to cotton dust at Arba Minch Textile Factory, Southern Ethiopia, 2017
November 2017
In many of the textile industries, workers are largely exposed to cotton dust, which can leave workers with respiratory disorders. The aim of this study was to evaluate respiratory status of workers exposed to cotton dust in Arba Minch textile factory, Southern Ethiopia, 2017. A comparative cross sectional study was done and 51 workers exposed to cotton dust in the factory and 51 age and sex matched controls were...
Correlates of abnormal hysteroscopy findings among infertile women in Nigeria
November 2017
This study aimed to evaluate the correlates of abnormal hysteroscopy among infertile women seen in 2 new Fertility/ Gynaecological Endoscopy units in Nigeria. Data was collected on biosocial and clinical characteristics of the patients as well as the findings at hysteroscopy and was analyzed with STATA software, version 12.0 SE (Stata Corporation, TX, USA) for the correlates of abnormal hysteroscopy using the...
Sociodemographic determinants of abnormal cervical cytology among HIV positive women in Nnewi, Nigeria
October 2017
Women living with human immunodeficiency virus (HIV) infection have a higher burden of premalignant lesion of the cervix. This may be influenced by their sociodemographic profile. To study the sociodemographic determinants of abnormal cervical cytology among HIV-positive women attending the adult HIV clinic in Nnamdi Azikiwe University Teaching Hospital Nnewi (NAUTH), Nnewi, Nigeria, the Pap smears of 110 HIV-positive...
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