International Journal of
Medicine and Medical Sciences

  • Abbreviation: Int. J. Med. Med. Sci.
  • Language: English
  • ISSN: 2006-9723
  • DOI: 10.5897/IJMMS
  • Start Year: 2009
  • Published Articles: 526

IJMMS Articles

The prevalence and management of hypertension in a population of adults with type 2 diabetes in the Adamawa Region (Cameroon): A retrospective analysis

September 2012

  This study aimed to assess the prevalence, treatment and control of hypertension in adult Cameroonian population in Adamawa with type 2 diabetes. Medical files of patients under follow-up at the hypertension and diabetes Unit of the Ngaoundéré Regional Hospital (Adamawa Region, Cameroon) were evaluated over one year period from January 2008 to January 2009. Medical follow-up consisted of a...

Author(s): Olivier Pancha, Adonis Koona Koona, Euloge Yiagnigni and Pierre Ndobo,

Signet ring carcinoma of the esophagogastric junction in a Nigerian man

September 2012

  Globally, the majority of cancers of the esophagogastric junction are adenocarcinomas. Of the four histological subtypes, the signet ring carcinomas are rare. There is a dearth of reports of this relatively rare histological finding from patients in sub-Saharan Africa. We present such a case in 69 year old Nigerian with advanced malignant disease.   Key word: Signet ring carcinoma,...

Author(s): Aderemi O. Oluyemi, Fatimah B. Abdulkareem and Nicholas A. Awolola

Prevalence of hepatitis B virus infection among blood donors with antibodies to hepatitis B core antigen

August 2012

Transfusion associated hepatitis B virus (TAHBV) infection continues to be a major problem despite mandatory screening for hepatitis B surface antigen (HBsAg). This is because HBsAg is not detected during the window period of the infection. The present study was designed to assess the prevalence and socio-demographic distribution of hepatitis B virus (HBV) infection in healthy blood donors of Erode District, Tamil Nadu....

Author(s): V. Lavanya, T. Viswanathan, S. Arul Sheeba Malar, A. Malarvizhi and K. Moorthy

Physicians' attitude about euthanasia and assisted suicide

August 2012

  This study was aimed to assess the physicians’ attitude on euthanasia and assisted suicide. This study was a cross-sectional study on 55 specialist doctors (Male and Female) about euthanasia and physician-assisted suicide (PAS) who worked in different hospital in Ahwaz city 2010. We explained the terms of euthanasia and PAS individually and required their attitudes and practices. All data were entered...

Author(s): Karami Khodabakhsh, Cheraghi Maria and Karami Nasibeh

Fatigue factors among regional pilots in Malaysia

July 2012

    Full Length Research Paper   Fatigue factors among regional pilots in Malaysia   Baba Md Deros1*, Dian Darina Indah Daruis2 and Nuhmandeen Bahurudeen1   1Department of Mechanical and Materials Engineering, Faculty of Engineering and Built Environment,...

Author(s): Baba Md Deros, Dian Darina Indah Daruis and Nuhmandeen Bahurudeen

Molecular prevalence of Hepatitis B virus infection in Khyber Pakhtunkhwa, Pakistan

July 2012

  Hepatitis B virus (HBV) infection is a major health problem in the developing countries including Pakistan. This study aimed to investigate various risk factors and prevalence of HBV in different areas of Khyber Pakhtunkhwa province, Pakistan. A total of 1439 individuals (1021 males and 418 females) suspected for hepatitis B infection were screened for HBsAg. All the samples were blindly analyzed for HBV DNA...

Author(s): Zia Ur Rahman Awan, Abdul Haleem Shah, Sanaullah Khan, Saeed Ur Rahman and Hafiz Munib Ur Rahman

Role of retinoid mediated microphthalmia-associated transcription factor (MITF) in melanoma

April 2012

  Retinoic acid is the most effective therapeutic drug for the treatment of many types of cancer, including melanoma. All-trans retinoic acid (ATRA) increases the protein level of MITF in melanoma cells within 2 to 4 days (Chan, 2007), indicating that RA induced MITF plays a vital role in its anti-proliferative action. On the contrary, MITF silencing can induce senescence in melanoma cells. These two...

Author(s): T. K. Basak, S. Chaudhuri and Shobha Gupta

Erythromelalgia in a patient treated with penicillin

April 2012

  Erythromelalgia is a rare neurovascular peripheral disorder of unknown cause that affects hands or feet causing painful skin redness in affected area. The attacks are periodic and are commonly triggered by heat, pressure, mild activity, exertion, insomnia or stress. Erythromelalgia can occur either as a primary or idiopathic disorder, or as secondary forms associated with hematologic diseases. Drugs have...

Author(s): Lora-Cabral A. and Pardos-Gea J.

Chronic care model for diabetics by pharmacist home health in Bangkok Metropolitan: A community based study

April 2012

  Diabetes was increased in Thailand with increasing burden of morbidity and mortality. There were 42.8% of diabetes patients in Bangkok who had been treated, but the disease conditions were uncontrolled. Diabetes with drug related problems (DRPs) frequently occurred, leading to problems of uncontrolled disease conditions. The objective of this study was to apply chronic care model (CCM) which has been...

Author(s): Sirirat Tunpichart, Rungpetch Sakulbumrungsil, Ratana Somrongthong and Duangtip Hongsamoot

Biological evolution of tryptophan and phenylalanine in the occurrence of breast cancer in Senegalese women

April 2012

  The reports provided by OMS in 2011 revealed that cancer is a major cause of death worldwide, causing 7.6 million deaths in 2008. Breast cancer represents in the world, the most common malignancy of women, and it seems that the low penetrance genes, frequently mutated in the general population would play an important role in the development of this cancer. The purpose of this study is to evaluate the...

Author(s): Fatimata Mbaye, Malick Fall, Ahmadou Dem and Mbacké Sembène,

Nutritional assessment of the diets in rickets prevalent communities in Kaduna State of Nigeria

April 2012

  Absorption (SHIMADZU MODEL 650) was used to determine the levels of calcium and phosphorus in the food samples. Wet digestion method was adopted for the food samples preparation. The results obtained showed that calcium levels in all foods were low with mean values of 0.056±0.02, 0.069±0.04 and 0.127±0.06 mg\kg (S.E.M) in Gonin Gora, Jankasa and Kaso respectively. Phosphorous levels were...

Author(s): Moji Taibat Bakare-Odunola, Turaki Kalik-Zik, Magaji Garba, Rasheed Adekeye Odunola and Kudi Bello-Mustapha

Periodontal myiasis treated by open flap debridement: A case report

March 2012

  Myiasis is an infestation of live vertebrate by dipterous larva, which feeds on living and dead host tissue, host products and byproducts. Here, we report a case of a female aged 35 years old, mentally retarded presented with severe pain, swelling, crawling worms in the upper teeth and lip region. She was a chronic mouth breather with very poor hygiene. On clinical examination, a larvae was seen in the...

Author(s): Syed Ansar Ahamd and Saif Khan

Uterine leiomyosarcoma presented as chronic inversion of uterus- A rare case report

March 2012

Sarcomatous change in uterine fibroid is termed leiomyosarcoma. The tumor originates from smooth muscle cells and is rare, accounting for 2 to 5% of all uterine malignancies. The said patient had the history of irregular bleeding, but not typical menorrhagia, which is the usual presentation in this tumor. A 40 year old, P4+0 women of North Indian origin, was admitted with huge polypoidal fungating mass with bosselated...

Author(s): Rekha Sachan , Pooja Gupta and ML Patel

Klinefelter Syndrome and Specific Learning Disability

March 2012

  47XXY aneuploidy is the most common disorder of gender chromosomes with a prevalence of 1: 700 males. However only 1/3 cases are diagnosed due to phenotypic variability and insufficient professional awareness of the syndrome. School children with Klinefelter syndrome (KS) present with language delay, learning disabilities and behavioral / social problems. Although Klinefelter syndrome (KS) with language based...

Author(s): Gajre Mona P and Rajeshwari Ganesh

Seroprevalence of Toxoplasma gondii in couples in Ramadi City using enzyme linked immunosorbent assay (ELISA)

March 2012

  Toxoplasma gondii is an obligate intracellular protozoan parasite that represents an actual public health problem. This study aims to investigate the prevalence of T. gondii among 91 couples in Ramadi City who were examined for the presence of antibodies against T. gondii using Enzyme Linked Immunosorbent Assay (ELISA). The overall anti-T. gondii (IgM and IgG) in both couples...

Author(s): Mohanad Mohammad, Shehab Ahmed and Abudalla Hussain

A new craniosynostosis syndrome

March 2012

  We report on a patient with bilateral multiple craniosynostosis involving the coronal and lambdoid sutures, high myopia, obesity, vertebral anomalies, minor acral anomalies and normal intelligence. The clinical features are not typical of any known craniosynostosis syndrome. Search of POSSUM, London Dysmorphology Database (LDDB), online Mendelian Inheritance in Man (OMIM), and the medical literature failed to...

Author(s): Cyrus Azimi

Prevalence of β-lactamase producing and non-producing Staphylococcus aureus associated with patients in intensive care unit

March 2012

  A total of one hundred twenty five samples were collected from intensive care unit of two main hospitals in Basrah: 74 clinical samples; Skin, blood, eye, nose, wounds and urine and 51 inanimate samples; bed, wall, instruments and addresses. The total of 334 isolates of bacterial types isolated from various sources as following numbers of isolating and percentages:Staphylococcus aureus 45...

Author(s): Ihsan Edan Abdulkareem AlSaimary

Study of oxidative stress in relation with antioxidant status in chronic bronchitis

March 2012

  Lipid peroxide plays an important role in inflammatory lung diseases. Increased epithelial permeability produced by cigarette smoke is likely to be mediated through depletion of the Total Antioxidant Capacity. Oxidative stress has been recognized as a central feature of smoke induced chronic bronchitis. Imbalance between oxidants and Total Anioxidant Capacity is also an established fact in these patients. 60...

Author(s): Anita M. Raut, A. N. Suryakar and Dilip Mhaisekar

Antimicrobial susceptibility of Enterococcus faecalis and a novel Planomicrobium isolate of bacterimia

February 2012

  During nucleotide sequences of 16SrDNA gene, Enterococcus faecalis was predominant in 322 samples; 11 isolates (100%) were from outpatients' vaginal swabs and 3 isolates (75%) from inpatients' blood samples. The three isolates from the blood showed two frame shift mutations "Deletion" at sequence positions 21 and 1076 bp to be 100% similar with type strain OG1RF. The isolates...

Author(s): Munaff J. Abd Al-Abbas

Frequency of rapid viral response (RVR) and influence of various factors on the response rates in chronic hepatitis C infected patients treated with interferon and ribavirin combination therapy

February 2012

  The aim of this study was to determine the frequency of rapid viral response (RVR) and influence of various factors on the response rates in chronic hepatitis C infected patients treated with interferon and ribavirin combination therapy. This study was conducted in Isra University Hospital, Hyderabad-Pakistan and Liaquat University of Medical and Health Sciences, Jamshoro/ Hyderabad, Pakistan, from July 2007...

Author(s): Memon Sadiq, Shaikh Samiullah, Devrajani Bikha and Shaikh Khalid

Prevalence of dementia varied with age, education and social network in a Senegalese elderly population of patients utilizing the Medico-Social and University Center of IPRES, Dakar-Senegal

February 2012

  With the ageing of the population, dementia is increasing. In Africa, studies on dementia of the elderly are seldom. However, dementia exists and is not well documented in Senegal especially among the elderly population. We conducted a study to estimate the prevalence of this disease among Senegalese elderly population utilizing the Medico Social and University Center of IPRES, Dakar-Senegal. The study was...

Author(s): Touré K., Coumé M., Sow P. G., Ndiaye N. N. D., Basse A., Diagne N., Sow A., Diop M., Seck L., Thiam M. H., Diop A. G. and Ndiaye M. M.

Comparative study of pulmonary functions after administration of albuterol and levalbuterol in patients with moderate to severe bronchial asthma

February 2012

  β2 - adrenoceptor stimulants play a key role in the management of bronchial asthma. This study was carried out on 80 patients of moderate to severe bronchial asthma. Group I (n = 40) received Albuterol 2.5 mg/2.5 ml and Group II (n = 40) received Levalbuterol 0.63 mg/2.5 ml TDS for 4 weeks. Baseline and post-treatment evaluation of lung function, respiratory rate, Total leukocytes Count, Total eosinophil...

Author(s): Kavita Rathore, Tarun Kumar Sharma, M. L. Aseri, Sunil Kumar Mathur, Rakesh Chandra Gupta, Satish Kumar Vardey, G. G. Kaushik and Maheep Sinha

Mixed Plasmodium falciparum and Plasmodium vivax infection with acute viral hepatitis in two brothers: A rare occurrence

January 2012

  Two brothers aged 14 and 17 years presented in our emergency department with complaints of fever and yellowish discoloration of eyes and urine for 6 and 10 days, respectively. They had similar clinical presentation, examination findings, laboratory biochemical derangements and positive results for rapid tests of Plasmodium falciparum and vivax species along with IgMEnzyme-linked...

Author(s): Neeraj Varyani, Sunny Garg, Kamlakar Tripathi, Lalit Prashant Meena, Uma Shankar Rath, Sourav Mishra and Garima Gupta

Ultrasound image acquisition by a personal computer- Application of artificial neural network

January 2012

  Traditional  probes  consist  of  40  to  60  crystals  each attached  to a pin attached  to a specialized cable of minimum 2  to 3 m. Each crystal has piezoelectric properties.   To capture  images by personal computers to  improve  accessibility  and  reduce  the  cost  of  having ...

Author(s): Mitra Ahmad Soltani-MD, MS

A survey of hepatitis B and C virus prevalence in human immunodeficiency virus positive patients in a tertiary health institution in North Eastern Nigeria

January 2012

  Co-infection of hepatotropic virus(es), with HIV has been associated with a reduced survival rate, an increased risk of progression to severe liver disease, and an increased risk of hepatotoxicity associated with active antiretroviral therapy. Information regarding prevalence of HBV and HCV co-infection with HIV in Nigeria is limited. This study was designed to determine the seroprevalence of...

Author(s): Ballah Akawu Denue, Babajide Ajayi, Abubakar Usman Abja, Abubakar Abdullahi Bukar, Cecilia Akawu, Ernest Ekong and Mohammed Bashir Alkali

Clinical effect of chronic osteomyelitis treated by integrated Chinese-Western therapy

December 2011

  Both Western and Chinese medicine have their own advantages in treating chronic osteomyelitis. In this study, we investigated the methods and clinical effect of chronic osteomyelitis treated by integrated Chinese-Western therapy. This is a prospective study. A total of 121 cases of chronic osteomyelitis (treated in the Military Training Medicine Institute hospital from January, 2002 to February, 2010) were...

Author(s): Chang Qi, Huang Tao and Huang Changlin

Study on the knowledge, attitude and practice about HIV/AIDS and its influencing factors among pregnant mothers in the social institute of health and hygiene of Dakar

December 2011

  Pregnant women are at higher risk of transmitting the infections to their foetus. This prompted the “prevention of mother to child transmission (PMTCT) program” in Senegal since 1998. The objective of this cross sectional study was to determine the knowledge, attitude and practice of pregnant mothers in the social Institute of health and hygiene of Dakar towards human immunodeficiency...

Author(s): Sow P. G. ,, Wade F., Toure K.,, Ndiaye I. P., and Traore I.,,

Antibiotic prescription and resistance: A contemporary literature review

December 2011

  Worldwide, antibiotics are among the most commonly used and misused drugs because of the perception in some practitioners and patients that antibiotic resistance is theoretical or only a minor risk. This review therefore aims to update knowledge and promote proper antibiotic prescription with the goal of optimizing use and halting the trend of rising resistance. A literature and internet (Medline, embase,...

Author(s): Godfrey B. S. Iyalomhe, Sarah I. Iyalomhe and Richard E. Eholor

Modulating effect of soy protein on serum cardiac enzymes in cholesterol-fed rats

December 2011

  The effects of soy protein on the activities of serum lactate dehydrogenase (LDH), alanine aminotransaminase (ALT), aspartate aminotransaminase (AST) and gamma-glutamyl transpeptidase (γ-GT) in rats fed cholesterol-diet were investigated. Rats were subjected to feeding over a period of six weeks on formulated diets containing: 20% soy protein with no cholesterol (group A); 20% soy protein with 5%...

Author(s): Nader Saki, Ghasem Saki, Fakher Rahim, Abolfazl Shiravi khoozani and Soheila Nikakhlagh

Human leukocyte antigen (HLA) Cw allele association among psoriasis patients from Western India

December 2011

  Psoriasis a common autoimmune disorder characterized by T cell mediated keratinocyte hyperproliferation known to be associated with the presence of certain specific HLA alleles. In this study our aim was to evaluate distribution of Human leukocyte antigen (HLA-Cw) susceptible allele of psoriasis from patients in Western India. The study included 84 Psoriasis patients and 91 normal individuals from...

Author(s): U. Shankarkumar, A. Shankarkumar and K. Ghosh

A comparative study on ofloxacin and azithromycin in combination with metronidazole to outpatients with pelvic inflammatory disease

December 2011

  This study aims to compare two oral treatments: Ofloxacin and Metronidazole, with Azithromycin and Metronidazole in outpatients with Pelvic Inflammatory Disease. This study was carried out by Randomized Clinical Trial in Al-zahra Women Hospital of Rasht. Two hundred women were selected based on eligibility criteria of having three out of the five following symptoms: lower abdominal pain, vaginal...

Author(s): Fariba Mirblook, Maryam Asgharnia, Kambiz Forghanparast, Mitra Ahmad Soltani

The influence of waist circumference and body mass index on the levels of adipokines, insulin and lipid parameters in normal overweight young Saudi females

November 2011

  Abnormal lipid profile, insulin resistance and hypoadiponectinemia are well recognized risk factors for cardiovascular and metabolic diseases. These risk factors are more prevalent among subjects with increased body adiposity. To study the relationships of body mass index (BMI) and waist circumference (WC) with fasting adipokines (leptin and adiponectin), lipid profile, and insulin sensitivity, a...

Author(s):   Maha Abdelkader Hegazi, Hanan Ahmad Al-Kadi, Eman Mokbel Alissa and Azra Kirmani

Comparison of hospital stay duration following total abdominal hysterectomy for benign disorders in private and general hospitals in Northern Iran (Rasht)

November 2011

  The objective of this study is to present the current data on hospital stay duration after hysterectomy for benign disorders and to compare this data in private with general hospitals in Rasht, Northen Iran. This is a cross-sectional study of all admissions for abdominal hysterectomies for benign conditions in general and private hospitals in Rasht during a six month-period.  Fisher exact and paired...

Author(s): Nader Esmailpour (MD), Fariba Mirblook (MD), Fatemeh Salamat (MSE) and Mitra Ahmad Soltani (MD,MS)

Patterns of electroencephalography (EEG) change against stress through noise and memorization test

November 2011

  This study aims to investigate the appearance of brainwaves due to mental stress caused by memory recall and mental calculation, and physical stress caused by noises. We obtainedElectroencephalography (EEG) data from 34 healthy subjects while they were at memory test interrupted by noises. Noise was accompanied by instability as it significantly decreased the relative power of the alpha wave of the left...

Author(s): Kwang Shin Park, Hyun Choi, Kuem Ju Lee Jae Yun Lee, Kwang Ok An, Eun Ju Kim

Association of socioeconomic status with health and birth outcomes: Maternal variables (Part 1)

November 2011

  Social class is one of the strongest known predictors of health or illness, but paradoxically very little is known about this variable. Adequate data on socioeconomic status (SES) and birth outcomes must be available to monitor socioeconomic inequality in birth outcomes. Our research wasdesigned to respond to this gap. This is the first large-scale survey of this kind in Ontario. Results from large scale...

Author(s): Cyrus Azimi and Mahshid Lotfi

Suppressive effects of Momordica charantia on pituitary-testicular axis and sperm production in male Sprague-Dawley rats

November 2011

  Momordica charantia plant is quite common in Africa and Asia, known in folkloric medicine to affect adversely the reproductive system by mechanism yet to be fully understood. The aim is to determine the effects of M. charantia with and without testosterone administration; on hormonal levels and sperm production (number and motility) in rats. Thirty male Sprague-Dawley rats were used,...

Author(s): Oshiozokhai Eboetse YAMA, Francis Ikechukwu DURU, Ademola Ayodele OREMOSU, Carmen Cressie NORONHA and Abayomi OKANLAWON

Anti-hyperlipidemic effect of aqueous leaf extract of Ocimum gratissimum in alloxan induced diabetic rats

November 2011

  This study aims at evaluating the effect of chronic administration of aqueous leaf extract ofOcimium gratissimum on total cholesterol level, triglycerides (TG), high-density lipoprotein (HDL) and low-density lipoprotein (LDL) in male albino rats. Twenty-one male albino rats of the Wistar strain weighing between 150 and 200 g were randomly assigned into 3 groups of 7 animals per group as control, diabetic...

Author(s): Ayinla M. T, Dada S. O, Shittu S. T, Olayaki L. A, Akiode A. O and Ojulari S. L

Reasons for patient visit to a rural general practitioner (GP) practice in Kwa-Zulu Natal, South Africa compared with those in first world countries

October 2011

  The common symptoms that patients present with, to a rural general practitioner (GP) in South Africa may be different to those of GP practices in urban areas  and different from patient presentations in first world countries. This study looked at the common reasons for which patients visited a GP in Kwa-Dukuza, South Africa over a four month period during 2006. Kwa-Dukuza is located on the North Coast of...

Author(s): I. Indiran Govender and L. H. Mabuza

Hypertension and classical risk factors in ambulatory patients: A hospital-based study in Adamawa region (Northern Cameroon)

October 2011

  The aim of this study was to evaluate the mean levels of blood pressure and hypertension (140 mmHg systolic or 90 mmHg diastolic pressure or treatment for hypertension) in a sample of non random ambulatory subjects attending Regional Hospital in Ngaoundéré (Adamawa region, Cameroon) and to evaluate conventional risk factors for hypertension in patients diagnosed with...

Author(s):  Pancha Mbouemboue Olivier, Koona Koona Adonis and Cacko Joachim

Volumetric measurements and anatomical variants of paranasal sinuses of Africans (Nigerians) using dry crania

October 2011

  The aim is to determine the volume of each sinus and to highlight the anatomical variants that are common in Nigerians’ dry crania. Twenty- four dried skulls of Nigerians from which the temporal bones had earlier been dissected were studied. A 0° sinus endoscopy (Telescope) was utilized to visualize the paranasal sinuses and their degree of pneumatization was noted. Vernier caliper was employed to...

Author(s): Amusa Y. B., Eziyi J. A. E., Akinlade O., Famurewa O. C., Adewole S. A., Nwoha P. U.and Ameye S. A.

Prevalence of stunting among school children of Government Urdu Higher Primary Schools in Azad Nagar and its surrounding area, Bangalore

October 2011

  Children are the future of the country. In India, children under 15 years of age constitute about 40% of the population. School children constitute a large pool of children of this age group. Nutritional status is a major component of school health services. The objectives of the study are (1) To assess the prevalence of stunting among school children of Government Urdu Higher Primary Schools (GUHPS) in Azad...

Author(s): Izharul Hasan, Mohd Zulkifle, and Abdul Haseeb Ansari

Serum markers as better predictors than Ranson, Imrie, and APACHE II systems in identifying the severity of acute pancreatitis

October 2011

  The aim of this paper is to evaluate the predictability of various scoring systems and serum markers in the assessment of the severity of acute pancreatitis. All consecutive patients with acute pancreatitis were prospectively studied. Body mass index was measured at the time of admission. The demographic data, etiology, mean hospital; stay, clinical, radiological, biochemical findings, morbidity, and...

Author(s): Abdu Hassan Alzobydi, Salman Yousuf Guraya and Shaista Salman

Ethnozoological study of traditional medicinal animals used by the people of Kafta-Humera District, Northern Ethiopia

October 2011

  Zootherapy is the healing of human ailments by using therapeutics based medicines obtained from animals. The present study reports the use of drugs of animal origin that have been practiced by the people of Kunama in Kafta-Humera district, Northern Ethiopia. Ethnozoological data was collected from 30 traditional healers who were selected based on their experience and recognition as experts from September to...

Author(s): Gidey Yirga, Mekonen Teferi and Yemane Gebreslassea

Computational design of cardiac activity

October 2011

  Cardiovascular physics is an interdisciplinary research area where the ideas and methods from mathematics, physics, and biology are synergistically applied for advanced medical diagnosis. The research on cardiac activity includes the development of efficient quantitative techniques and theoretical approaches, as well as the use of mathematical reasoning to gain insight into the cardiovascular system. However,...

Author(s): Md. Shoaibur Rahman

Polymorphisms of the deoxyribonucleic acid (DNA) repair gene XRCC1 and risk of colon cancer in Saudi patients

September 2011

  The aim of this study was to investigate the possible association of three single nucleotide polymorphisms (SNPs), C194T, G399A, and G280A, in the X-ray repair cross-complementing group 1 (XRCC1) gene with the risk of developing colon cancer in Saudi patients. Samples of 65 colon cancer patients, aged 45 to 80 years old, and 65 age-matched controls were genotyped. The results demonstrated that...

Author(s): Rowyda N. Al-Harithy and Wedam M. Al-Ghazzawi

Morphometric study of endoscopic approach to the cerebellopontine angle

September 2011

  Cerebellopontine angle (CPA) tumors account for 10% of all intracranial tumors. The endoscopic approach to CPA is being used increasingly as the availability of variable angled endoscope allow for operative views of lesions at angles not visible by the microscope and it is minimally invasive. The authors present findings based on the endoscopic study performed on three cadaveric heads (six sides) through...

Author(s): T. S. Gee, H. K. Pal, A. K. Aaijaz, I. Zul and A. K. Shamim

Radiological findings of breast cancer screening in a newly equipped centre

September 2011

  This study is to appraise the imaging findings of all patients that came into the breast imaging unit for screening and perhaps buttress the importance of a government policy guideline on screening and treatment for breast cancer in Nigeria. This prospective study was carried out among all consecutive patients that came for screening in the breast imaging unit of the University of Ilorin Teaching Hospital...

Author(s): Halimat J. Akande, Olalekan I. Oyinloye, and Bola B. Olafimihan

L-arginine treatment alters the pattern of rat maternal aggressive response toward an intruder entering the homing cage

August 2011

  Maternal aggression toward intruders is temporarily expressed during lactation in association with the rearing and protection of offspring to promote their survival and growth. This normal component of maternal behaviour that requires both the hormonal changes occur at the end of pregnancy and due to the presence of newborn for its establishment analyzed in Wistar rats. The effects of nitric oxide (NO) by...

Author(s): Esther Pérez-Torrero, Margarita I. Hernández-Urbiola, Anaid Cadena-Estrada andCarlos I. Silva-Barrón

Hepatoprotective potentials of Butea monosperma stem bark extract against carbon tetrachloride induced hepatotoxicity in albino rats

August 2011

  Carbon tetrachloride (CCl4) pharmacological tool was used to produce liver damage in rats. Silymarin (100 mg/kg) and extract of Butea monosperma (shown to be hepatoprotective substances) prevented the CCl4 induced toxicity. Hydroalcholic extract of the stem bark of B. monosperma was evaluated for its hepatoprotective. This in vitroefficacy was reinforced by a significant dose...

Author(s): Prashant Tiwari, Kuldeep Kumar, Rajnikant Panik, Alok Pandey, Ashish Pandeyand Pratap Kumar Sahu

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