Journal of
Infectious Diseases and Immunity

  • Abbreviation: J. Infect. Dis. Immun.
  • Language: English
  • ISSN: 2141-2375
  • DOI: 10.5897/JIDI
  • Start Year: 2009
  • Published Articles: 80

JIDI Articles

July 2011

A prospective clinical study of incidence of hepatorenal and hematological complications in dengue fever and management of symptomatic bleed in bundelkhand region of Northern India with fresh whole blood

Dengue is the most rapidly spreading mosquito-borne viral disease in the world. Besides bleeding, cases of hepatic and renal dysfunction in dengue fever are increasing in incidence. In management of hemorrhagic complications, fresh whole blood is far superior to platelet transfusion and fresh frozen plasma. This work is aimed at studying the incidence of hepatorenal and haematological complications and the management of...

Author(s): JAIN, P. K., SHARMA Awadhesh Kumar, AGARWAL Navneet, SIDDIQUI Mohd Zaki, PAWAL Praveen, GABA Ripudaman and SRIVASTAVA Swati

  • Article Number: 10B13823807

June 2011

Efficacy and mechanism of nasal irrigation with a hand pump against influenza and non-Influenza viral upper respiratory tract infection Huafei Ao1, Qin Wang1, Baofa Jiang2 and Peter He3*

To investigate if nasal irrigation could impact the severity and duration of viral URTI. 22 patients with new onset non-influenza URTI were randomized to Control (Control, N=12) or Nasal Irrigation Group [NI-Flu (-), N=10], and 8 patients with new onset influenza URTI were assigned to Nasal Irrigation Group [NI-Flu (+), N=8]. Patients in control were treated with standard of care, those in Nasal Irrigation Groups...

Author(s): Huafei Ao, Qin Wang, Baofa Jiang and Peter He

  • Article Number: 31B7A463724

June 2011

A study of occurrence and histopathology of Mycoplasma infection in sheep in Tehran suburb, Iran

The authors have requested the retraction of this article.

Author(s): Mohkber Dezfouli M. R., Sadeghian S., Javanbakht J., Hobe Naghi R. and Lakzian A.

  • Article Number: 96E863E3740

June 2011

Clinical profile of children presenting with measles in a Nigerian secondary health-care institution

The prognosis of measles is determined largely by host factors. The objective of this study is to document the clinical profile (host factors) of children presenting with measles in a Nigerian secondary health-care institution. In this case-series study, 77 children with measles (diagnosed clinically), admitted into St Philomena Catholic Hospital, Benin City were recruited over a 4-year period. The age, sex, presenting...

Author(s): Alphonsus N. Onyiriuka

  • Article Number: A99DBD73772

May 2011

Infections of the central nervous system by Candida

At present, the species of Candida are the increasing causes of infections in neutropenic and non neutropenic patients, and they enable the production of important morbimortality. Invasive candidiasis is the most frequent opportunistic mycosis and when there is central nervous system (CNS) involvement, mortality associated to mycosis increase. Unfortunately, studies based in autopsies prove that the prevalence...

Author(s): Natalia Aristizabal Henao and Basilio Vagner,

  • Article Number: 98E16F23669

May 2011

Prevalence of dengue among clinically suspected febrile episodes at a teaching hospital in North India

Dengue is one of the most serious mosquitos borne viral infection mainly affecting tropical and subtropical countries of the world. In absence of specific treatment and vaccine for dengue fever (DF); vector control is the only method by which spread of dengue can be prevented. As effective control and preventive programmes depend upon improved surveillance data, this study was done to report the seroprevalence...

Author(s): Atul Garg, Jaya Garg, Y. K. Rao, G. C. Upadhyay and Suman Sakhuja

  • Article Number: C13CE353684

May 2011

Pattern of default among tuberculosis patients on directly observed therapy in rural primary health care centres in Ogun State, Nigeria

This study was designed to identify risk factors associated with defaulting during TB treatment and indicate specific adjustments to be made. This study is a retrospective, cohort study. Information on all TB patients attending clinic for treatment from 1st April 2004 to 30th June 2007 was collected using a data collection form. A total sample of 938 patients was reviewed. The overall default rate among the TB patients...

Author(s): Amoran O. E., Osiyale O. O. and Lawal K. M.

  • Article Number: 81E88BB3696

April 2011

Aspergillus tracheobronchitis in an immunocompetent critically ill patient

Aspergillus tracheobronchitis (ATB) is a rare cause of respiratory failure in the critical care unit. Most commonly occurring in immunocompromised patients with underlying haematological malignancy, solid organ transplant, or HIV/AIDs, ATB is infrequently encountered in patients without underlying immunologic derangement.  This brief report describes a single case of ATB in a critically ill patient with no...

Author(s): Steve Reynolds, Stephen Blackie and Jason Faulds,

  • Article Number: 63482983559

April 2011

An immunoassay using cord factor antigen of Mycobacterium tuberculosis for the confirmatory diagnosis of intracranial tuberculoma

Demonstration of Mycobacterium tuberculosis bacillus in an intracranial tuberculoma by  bacteriological culture and staining methods are difficult. Hence the objective of this study is to describe an immunoassay to detect the presence of cord factor antigen of M.tuberculosis in intracranial tuberculoma. Cord factor antigen of M. tuberculosis in the surgical specimens of...

Author(s): Mathai A., Neelima R., Harikrishnan V. S. and Radhakrishnan V. V.

  • Article Number: 70C7AC23573

April 2011

Redistribution of fetal blood flow in response to an acute fever episode during pregnancy in comparison with malaria

The objective of the study was to determine if maternal fever during pregnancy alter placental function and induce fetal hypoxia. 31 pregnancies complicated by fever were studied. Uterine (UTRI), umbilical (URI), fetal cerebral (CRI ) Doppler resistance index and amniotic index were measured on admittance (day 0; d0) and after treatment and fever release (day 2 to 4; d2-4). From d0 to d2-4, UTRI decreased in...

Author(s): G. Carles, F. Dallah, G. Helou, N. Alassas, W. El Guindi and P. H. Arbeille

  • Article Number: 49C83073605

April 2011

Helicobacter pylori-DNA in nasal polyp tissues in compare with inferior nasal turbinate tissues: A case-control study in Tehran, Iran

This study is aimed at comparing serum Helicobacter pylori antibodies and H. pylori–DNA in tissue between cases with nasal polyps and controls. A case control study was conducted in the Department of Otorhinolaryngology, Rasul Hospital, Tehran, Persia between 2007 and 2008 upon polyp tissues from 62 nasal polyposis cases and inferior nasal turbinate mucosa from 25 controls. H. pylori-DNA was...

Author(s): Samileh Noorbakhsh, Azardokht Tabatabaei Mohammad Farhadi and Ahmad Reza Shamshiri

  • Article Number: 802E2163634

March 2011

Parry-Romberg syndrome: A possible association with Lyme borreliosis

Parry-Romberg syndrome or progressive facial hemiatrophy is a rare entity of unknown etiology characterized by unilateral atrophy of the skin, subcutaneous tissue and the underlying bony structures. A case of a 4-year-old girl with Parry-Romberg syndrome and borreliosis is reported. No sure link is established between these two entities but their coincident occurrence in our patient is noted.   Key...

Author(s): Filipa Ventura, Joana Gomes, Catarina Vilarinho, Ana Paula Vieira, José Carlos Fernandes, Fernando Mota Garcia and Celeste Brito

  • Article Number: 8170FF33499

March 2011

A cost effectiveness analysis of the H1N1 vaccine strategy for Ontario, Canada

In Ontario, Canada, a mass vaccination strategy was developed and implemented to mitigate the effects of the 2009 pandemic influenza A (pH1N1). This study investigated its cost-effectiveness, mirroring actual events in Ontario, compared to no vaccine strategy. From a societal perspective, 1,780,491 cases and 154 deaths were averted through vaccine administration; the incremental cost effectiveness ratio predicted that...

Author(s): A. Durbin, A. N. Corallo, T. G. Wibisono, D. M. Aleman, B. Schwartz and P. C. Coyte,

  • Article Number: BE7C5743504

March 2011

Targeted indoor insecticide and malaria control in the western highlands Kenya

The study investigated the use of targeted indoor residual spraying (IRS) as a single malaria intervention in the western highlands, Kenya. Houses were randomly selected in study sites and IRS targeted 30% of houses at focal sites ‘hotspots’ at valley bottoms. Indoor resting densities of adult Anopheles gambiae s.s were monitored biweekly by pyrethrum spray capture in sprayed and control houses....

Author(s): Mulambalah Chrispinus S., Siamba Donald N., Ngeiywa Moses M. and Vulule John M.

  • Article Number: 8406F293533

February 2011

Fertility in cimetidine and bromocriptine treated rats

The present study was designed to see the role of drugs affecting serum prolactin upon the morphology of the gonad of male rat by giving bromocriptine to one group of animals concurrently with cimetidine. This study was conducted at the Department of Anatomy, Army Medical College (AMC), Rawalpindi in collaboration with National Veterinary Laboratories (NVL), Chak Shahzad, Islamabad. Ninety adult young male albino rats...

Author(s): Qamar Hamid, Liaqat Ali Minhas and Sadaf Hamid

  • Article Number: 0A6AAC93446

February 2011

Studies on the interaction between IgA, lactoferrin and lysozyme in the breastmilk of lactating women with sick and healthy babies

The IgA, lactoferrin and lysozyme levels in breastmilk samples of mothers with healthy babies and mothers whose babies developed septicaemia were analyzed by the enzyme – linked immunosorbent assay. The IgA level in the milk of mothers with healthy babies decreased from 183.48 ± 114.91 mg/l in colostrum to 147.75 ± 114.6 mg/l in mature milk while the level in mothers whose babies developed...

Author(s): Ella, E. E., Ahmad, A. A., Umoh, V. J., Ogala, W. N., Balogun, T. B. and Musa, A.

  • Article Number: 45F10A83455

February 2011

Tumor necrosis factor gene polymorphisms and susceptibility to rheumatoid arthritis in regional Tunisian population

Rheumatoid arthritis (RA) is a complex multifactorial disease caused by environmental influences and an unknown number of predisposing genes. The present study was undertaken in order to investigate the possible association between RA disease and the TNFgene promoter polymorphisms -308A>G, -1031 T>C and the TNFβ polymorphism+252A>G (LTA252A>G) in the Tunisian population. We compared the...

Author(s): E. Fakhfakh Karray, I. Bendhifallah, K. BenAbdelghani, K. Hamzaoui and L. Zakraoui

  • Article Number: CA0D0C33463

January 2011

Prevalence of gastrointestinal parasites of laboratory animals at Ethiopian Health and Nutrition Research Institute (EHNRI), Addis Ababa

A study on prevalence of gastrointestinal parasites of laboratory animals was conducted from November 2009 to March 2010 at the Ethiopian Health and Nutrition Research Institute (EHNRI), Addis Ababa. For this study, faecal samples were collected from a total of 210 laboratory animals which include 140 mice (Swiss albino), 56 rats (Wistar) and 14 guinea pigs (Cavia porcellus). The collected faecal samples were...

Author(s): Tadesse Gudissa, Hailu Mazengia, S. Alemu and Haileleul Nigussie

  • Article Number: 34872143416

January 2011

siRNA-mediated silencing of translationally controlled tumor protein induces apoptosis and inhibits cell growth

Translationally controlled tumor protein (TCTP) is an evolutionally highly conserved protein which has been implicated in many cellular functions that are related to cell growth, death and tumorigenesis. We used a DNA vector-based RNA interference approach by expressing shRNA to knockdown TCTP in MCF7 cells for evaluating its antitumor effect and its molecular mechanism. TCTP shRNA treatment MCF7 cells...

Author(s): Zeng-Chun Ma, Qian Hong, Yu-Guang Wang, Hong-Ling Tan, Cheng-Rong Xiao, Qian-De Liang, Bei-bei Lu and Yue Gao

  • Article Number: 0E212933425

January 2011

Direct antiglobulin test (Coombs’) positive autoimmune hemolytic anemia induced by Epstein-Barr virus infectious mononucleosis in two children

Primary Epstein-Barr virus infection in children is usually asymptomatic, but some children or young adults manifest infectious mononucleosis with typical symptoms of fever, pharyngitis, lymphadenopathy, hepatosplenomegaly and a typical lymphocytosis. The infection caused by Epstein-Barr Virus (EBV) can be followed by immunological complications. One of these is autoimmune hemolytic anemia (AIHA) that it is rare but...

Author(s): Mehmet Akin, Özlem Şahin, Kazim Küçüktaşci, Burçin  Kaya, Ersin Gozkeser, Murat Çağlar and Firat Erdoğan

  • Article Number: 5FFF20A3430

December 2010

Screening of household members and contacts of patients with acute brucellosis to detect unrecognized cases

Acute brucellosis among household members of index cases due to common food sources is reported. The aim was to screen family members and coworkers of patients with acute brucellosis to detect unrecognized cases. A descriptive study was conducted among contact cases of acute brucellosis patients. Five millilitre of venous blood samples were taken from contact cases to measure Brucella antibody IgM, IgG, and IgA. Thirty...

Author(s): Zohreh Aminzadeh, Babak Farrokhi, Hossein Akhavan Zanjani, Farshid Aliyari, Zivar Baiati, Fatemeh Navaei and Jamal Mirzaei

  • Article Number: 36768344341

December 2010

Increased incidences of Salmonella, Plasmodium falciparum and hepatitis C viral specific circulating immune complexes in participants from malaria endemic and HIV prevalent area of Nigeria

The present study used dissociated circulating immune complexes (CIC) to identity the burden of exposure to certain infectious agents. The participants were divided into HIV seropositive group (n=100) and HIV seronegative  group (n=100). Polyethylene glycol (PEG) 6000 and phosphate buffer techniques were used for precipitation and dissociation of CIC in sera. The dissociated CIC were tested...

Author(s): Chukwudi M. Ezeani, Chinedum C. Onyenekwe, Confidence K. Wachukwu, Chukwuemeka S. Meludu, Ositadimma M. Ifeanyichukwu, Nkiruka R. Ukibe, Anthony O. Igwegbe, Daniel C. Anyiam and Amobi Ilika

  • Article Number: 3835AA54348

November 2010

Virological diagnosis of dengue fever in Jeddah, Saudi Arabia: Comparison between RT-PCR and virus isolation in cell culture

A total of 233 serum samples were collected from patients presenting to King Abdulaziz University Hospital with suspected cases of Dengue Fever (DF) from 2006 to 2008. Dengue virus was successfully isolated from 70 samples by culture on C6/36 and LLC-MK2 cells; it was then detected by indirect immunofluorescence assay (IFA). The cytopathic effect (CPE) of dengue virus on C6/36 appeared in most of the samples within 1-4...

Author(s): Esam Azhar, Moujahed Kao, Matthias Niedrig, Badr Masri, Azad Godus, Raed Badierah, Nassem Khan, Adnan Almazrooa, Ahmad Ashshi and Ghazi Jamjoom

  • Article Number: 17DF2D04311

November 2010

Immunogenic evaluation of a recombinant 49-kilodalton outer membrane protein of Salmonella typhi as a candidate for a subunit vaccine against typhoid

Typhoid poses a global public health concern. Presently available vaccines against typhoid have certain drawbacks that make them unsuitable for mass immunization, especially to children and elderly people. The outer membrane proteins (OMPs) of Salmonella have strong potential for the development of a candidate subunit vaccine against typhoid. We previously reported that a 49 kDa OMP confers protection against...

Author(s): Nowsheen Hamid Bhat and S. K. Jain

  • Article Number: C932D034316

April 2010

Serological evidence for Chlamydia pneumoniae infection following diphtheria-tetanus-pertussis booster vaccination

Increased mortality and morbidity with intracellular pathogens has been reported in females with diphtheria-tetanus-pertussis (DTP) as their most recent vaccination. Within a randomised trial, we investigated the effect of DTP on Chlamydia pneumoniaeserology. Eighteen-month-old children were randomised to DTP booster and oral polio vaccine (OPV) or OPV only. Blood samples collected from 523 children at baseline and...

Author(s): Jane Agergaard, Grethe Lemvik, Ernesto Nante, Marie Helleberg, Jens Nielsen, Christine Stabell Benn, Peter Aaby, and Lars Østergaard

  • Article Number: 7F46DA74277

April 2010

The disease progression associated with pirital virus infection in the Syrian golden hamster

Arenaviruses are negative strand RNA viruses that can cause disease and hemorrhagic fever in humans. Typically, research with the hemorrhagic fever causing - arenaviruses requires working in a Biosafety level (BSL)-4 environment which increases the time and cost of testing vaccine and therapeutics. Therefore, we have expanded on the previously described pirital virus (PIRV) animal model for human arenaviral hemorrhagic...

Author(s): Eric M. Vela, Katherine Knostman, Richard Warren, Jennifer Garver and Rachelle Stammen

  • Article Number: 60A10EB4293

December 2009

Circulating antigens of Schistosoma parasites in urine of schistosomiasis patients in Central Sudan

This study was aimed to detect circulating antigens of the schistosoma parasites in urine of schistosomiasis patients living in two camps, Hababna and Elshajara camps within Tyieba Elshiekh Elgorashi village, located North West from Hassahiesa city in the Gezira state- central Sudan. The prevalence of S. haematobium in the two camps was 15.4% and the prevalence of S. mansoni was 53.8%. Urine samples...

Author(s): Ashraf S. Yousif, Eshtiyag A. Abdelkareem, Salma M. Elhag, Lemeis A. Elgimeaabi, Magdi A. Ahmed, Ehab A. Frah, Ahmed Babiker and Atif A. Elagib

  • Article Number: 0F9FF8C4263

December 2009

Evaluation of Newcastle disease antibody level after different vaccination regimes in three districts of Amhara Region, North-western Ethiopia

Evaluation of the Newcastle Disease (NCD) antibody level after different vaccination regime was conducted on chickens distributed at the age of day-old in three districts of Amahara region using sera analysis. Three vaccination regimes on chicks against Newcastle using live lentogenic stains; Hitchener B1 (at the age of day-old) and La Sota (at the age of 21st and 60th days of age) were used. The overall antibody level...

Author(s): Hailu Mazengia, Esayas Gelaye and Mohamed Nega

  • Article Number: AD719954269

November 2009

Absent uvula and thrombocytopenia in an African infant with job’s syndrome: Case report and review of literature

Job’s syndrome, a subset of the Hyper-immunoglobulin E (IgE) recurrent Infection Syndrome (HIES), is a rare primary immunodeficiency disorder characterized by a classic clinical triad of recurrent staphylococcal abscesses, recurrent cyst-forming pneumonia, and markedly elevated serum IgE level. To date, slightly more than 200 cases have been published worldwide. Here we review HIES and report one case of...

Author(s): James Chipeta, Jackie Banda, Mbinga Mbinga and Somwe Wa-Somwe

  • Article Number: E10D3E74251

November 2009

Prevalence of SCCmec types in methicillin resistant Staphylococcus intermedius in healthy pets from Southeastern United States

Methicillin resistant Staphylococcus aureus (MRSA) and methicillin resistantStaphylococcus intermedius (MRSI) are both major causes of skin and wound infections in humans and domesticated animal populations respectively. In order to investigate the colonization rates in pets, nose, mouth, or skin swabs were taken from 74 healthy pets (61 dogs and 13 cats) in south Louisiana, USA.Staphylococci were...

Author(s): Tessie Rachal, Kasey Leonard, Lauren Martinez, Jenny Gonzales Breaux, Angela Corbin and Rajkumar Nathaniel

  • Article Number: 15FCCB54256

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