African Journal of
Biochemistry Research

  • Abbreviation: Afr. J. Biochem. Res.
  • Language: English
  • ISSN: 1996-0778
  • DOI: 10.5897/AJBR
  • Start Year: 2007
  • Published Articles: 381

AJBR Articles

July 2013

Effects of organic manures on the physicochemical properties of crude oil polluted soils

  The impact of crude oil pollution on the edaphic physicochemical parameters and the influence of incorporation of different types of organic manures in the polluted soils were investigated. The factorial set of treatments were six levels of crude oil pollution (0, 30, 60, 90, 120 and 150 ml), while amendment treatments were done after two weeks of pollution treatment, using the following organic manures:...

Author(s): N. A. Obasi, Eberechukwu Eze, D. I. Anyanwu and U. C. Okorie

  • Article Number: E2098ED11490

July 2013

Seed oil diversity of Ethiopian linseed (Linum usitatissimum L.) landraces accessions and some exotic cultivars

  Keeping in view, lack  of adequate information on  genetic  diversity  in  the  Ethiopian linseed (Linum ustatisimum L.) landraces on one hand and its immense importance in the agricultural systems on the other hand in Ethiopia, 49 accessions collected from five regions of Ethiopia together  with fifteen exotic cultivars were  used  in  this ...

Author(s): Mulusew Fikere, Firew Mekbib and Adugna Wakjira

  • Article Number: 163771D11498

July 2013

Protein sparing effects of carbohydrate in African catfish, Clarias gariepinus

  Feeding trial was conducted to examine the protein sparing effects of carbohydrate in Clarias gariepinus, an attempt to reduce the feed cost. C. gariepinus fingerlings mean weights of 8.32 ±0.04 g were randomly allotted into a group of 15 fishes per tank in triplicate of 10 treatments. They were fed on nine experimental diets and a commercial Catfish Reference Diet (CRD). The formulated...

Author(s): Orire A. M. and Sadiku S. O. E.

  • Article Number: DF0BF5011565

July 2013

The effect of quinine on myeloperoxidase activities in the neutrophil

  Quinine has been known to impair the functions of polymorphonuclear neutrophils (PMN). Myeloperoxidase is the most abundant enzyme found in the neutrophil. The enzyme is known to catalyse the formation of hypochloride from hydrogen peroxide and chloride, as part of the normal cellular defence system in the polymorphonuclear neutrophil. This study was carried out to investigate the effect of quinine on...

Author(s): J. B. MINARI, O. B. OLOYEDE and T. A. OLADIJI

  • Article Number: F7CECBF11576

July 2013

Stability study of smoked fish, horse mackerel (Trachurus trachurus) by different methods and storage at room temperature

  The present study assessed the effect of hot smoke using wood and charcoal dry heat on keeping quality of Trachurus trachurus fish fillet, skin, head and bones (SHB). T. trachurus was smoked using the altona kiln at 80 to 105°C for eight hours, placed in cain woven baskets to cool off, packaged in sealed transparent polythene bags and left on shelf for 7 days at ambient...

Author(s): O. T. Adeyemi, O. O. Osilesi, F. Onajobi, O. Adebawo and A. J. Afolayan

  • Article Number: 3A426FD11586

June 2013

Effects of water stress on physiological processes and yield attributes of different mungbean (L.) varieties

  In order to investigate the effect of water stress on Mungbean varieties and its physiological responses to yield, a field experiment was carried out according to split plot design with twenty treatments combination and three replications during 2010 and 2011 at Crop Research Centre of Sardar Vallabhbhai Patel University of Agriculture and Technology, Meerut (Uttar Pradesh). The results indicated that drought...

Author(s): R.K. Naresh, Purushottam, S.P.Singh, Ashish Dwivedi and Vineet Kumar

  • Article Number: A17DA4611458

June 2013

Study of interaction between lysozyme-aminoglycosides and penicillin

  The interaction between aminoglycosides-lysozyme and penicillin-lysozyme was studied by using UV and IR spectroscopy. The study was started with the purification of lysozyme from hen, quail, duck and pigeon and designated as HEWL, QEWL, DEWL and PEWL, respectively. Aminoglycosides (kanamycin and streptomycin) and penicillin (ampicillin) interactions with lysozyme were explored in this investigation. The study...

Author(s): Anand Krishnamurthy, Sudarsanam D, Anantharamanan R. and Najmeh Alirezaie

  • Article Number: 1BA17A511469

May 2013

Effects of sub-chronic exposure to moderate intensity static magnetic field (SMF) on oxidative stress parameters of male rats

  Increasing exposure to electromagnetic fields has become inevitable for people living in industrialized environments. Magnetic fields can increase the production of free radicals; reports also suggest that extremely low frequency magnetic fields (ELF-MF) can increase free radical life-span. This study evaluated the effects of moderate intensity static magnetic field (SMF) (56 Hz, 41 mT, 6 h/day) on the...

Author(s): A. A. Omonkhua and D. D. Abajingin

  • Article Number: 08ABC1D11432

May 2013

Hot water and molybdenum dips: The case of antioxidant assays in lemon flavedo during cold storage

  Antioxidants are part of the plant’s defense system, protecting tissue against oxidative stress. In citrus fruit, oxidative stress can occur during extended cold storage ultimately result in chilling injury. Citrus fruit contain certain rind antioxidants which occur in different forms (lipophilic and hydrophilic). Previous studies demonstrated a synergistic relationship between hot water dips (HWD) and...

Author(s): Nhlanhla Mathaba, and Isa Bertling

  • Article Number: CCC149211443

April 2013

Biochemical markers of ethnic Pakistanis: A correlation between genetic-aloofness and nutritional status affecting average age of each group

  The nutritional status and ethnic-aloofness (non mixed genomes owing to lack of cross marriages) might have direct impact on the average age and quality of health of the individuals belonging to different racial groupings. North Western region of Balochistan around Quetta, Pakistan, has diverse ethnic populations which afford a unique genomic pattern in addition to specific life style, pattern of eating,...

Author(s): Abrar Hussain Khan, Muhammad Azhar Sherkheli, Muhammad Asif, Mahmood Rasool  and Agha Muhammad Raza

  • Article Number: 967FCE211405

April 2013

Tomato supplement ameliorates castration-induced oxidative stress in the rat

  Castration has previously been shown to induce oxidative stress. Previous studies have shown tomato to be a potent anti-oxidant which reduces oxidative stress in many disease conditions. However, the likely role of tomato in ameliorating castration-induced oxidative stress has not been studied and was of interest to us. The present study looked into the effect of tomato supplement on the plasma level of...

Author(s): Ayobami Oladele Afolabi, Oluwatosin Oluwaseun Osho and Isiaka Abdullateef Alagbonsi

  • Article Number: 4DF2AC811419

March 2013

Comparative osmotic fragility of three erythrocyte genotypes (HbAA, HbAS and HbSS) of male participants administered with five antimalarial drugs

n vivo study was carried out to ascertain the mean corpuscular fragility (MCF) index and corresponding stability of three erythrocyte genotypes (HbAA, HbAS and HbSS) before (control; t = 0 h) and after (tests; that is, at t = 3, 6 and 18 h) five (5) antimalarial drugs (FansidarTM, HalfanTM, Quinine, CoartemTM, and Chloroquine phosphate) were administered to male participants. Clinically confirmed healthy...

Author(s): P. C. Chikezie, A. A. Uwakwe and C.C. Monago

  • Article Number: AB649E611104

February 2013

Nutrigenomic studies of orange juice and vitamin c on gene expressions in neuronal tissues of Sprague Dawley rats

  Nutrigenomics, a nascent field in nutrition and molecular biology plays a pivotal role in understanding the influence of bioactive dietary components on the structure, integrity and functions of the genome. In this study, the comparative effects of vitamin C (Vit C) and Nigerian local orange juice on the gene expression levels of superoxide dismutase (sod), tumour necrosis factor receptor...

Author(s): Osaretin Albert T.  Ebuehi, Yusuf Salami, Ayorinde B. James and Imelda N. Mgbeadichie

  • Article Number: BC57E8111380

February 2013

Oxalate metabolism by Sclerotinia sclerotiorum, a fungal pathogen in soybeans

  Pathogenesis of Sclerotinia sclerotiorum mainly depends on production of oxalate (Lib.) de Bary, but the mechanism by which the oxalate is produced is not well understood. Control of Sclerotinia stem rot (SSR) in soybean which is caused by this ubiquitous phytopathogenic fungus requires the knowledge of oxalate synthesis by S. sclerotiorum. Nine isolates from infected soybeans and soils were...

Author(s): Mbiri A., Gatebe E., Ndung’u M., Kariuki W. and Mwangi E.

  • Article Number: 1C5E17D11392

January 2013

Serum ghrelin levels in Syrian obese patients with diabetes mellitus type II

  The serum ghrelin levels had been studied in three groups of subjects׃ First group was normal weight (11 men and 9 women), non obese, non diabetic, 38 ± 12 years old, with BMI mean about 23.8 kg/m2 and did not take any drugs. The second group was overweight (18 men and 13 women), non diabetic, 40.6 ± 9.9 years old, with BMI mean about 36.34 kg/m2. This group was apparently healthy and...

Author(s): Moayad A. Saad, Younes M. Kabalan and Faizah A. Al-Quobaili

  • Article Number: A6D8E9911350

January 2013

Plasma concentration of acylated ghrelin in patients with Alzheimer’s disease

  Ghrelin is a hormone produced in the stomach and tightly linked to the regulation of energy balance and cognitive processes. It may be altered in Alzheimer’s disease (AD), a dementia syndrome markedly influenced by metabolic diseases. The aim of this study was to evaluate the changes in the plasma concentration of acylated ghrelin in patients with AD. The study included 71 people 37 in the case...

Author(s): Akbarzadeh S, Yusefi F, Jafari SM, Khosravizadegan F, Moula A, Salimipour H, Eghbali SS, Motamed N, Hajian N, Rahbar A, Abdi MR, Hazrati S and Movahed A

  • Article Number: 1E7A72111363

December 2012

Effects of Emilia praetermissa leaf extract on the haematological and biochemical parameters of stress induced ulcerated Wistar rats

Effects of Emilia praetermissa leaf extract on the haematological and biochemical parameters of cold-water stress induced ulceration in albino rats were the focus of this study. Blood samples collected from stress induced ulcerated Wistar rats by cold water immersion were used to evaluate the haematological and biochemical parameters. This study was conducted using twenty rats randomly divided into four...

Author(s): A. O. Ebunlomo, A. O. Odetola, O. Bamidele, J. N. Egwurugwu, S. Maduka and J. Anopue

December 2012

Assessment of the potency of some selected anti-malaria drugs on the supplements of vitamin B2 and orange fruit juice (combination therapy)

Current practice in treating cases of malaria is based around the concept of combination therapy, since this offers several advantages - reduced risk of treatment failure, reduced risk of developing resistance, enhanced convenience and reduced side-effects. The effect of the supplements vitamin B2 (Riboflavin) and orange fruit juice on the potency and efficacy of some selected anti-malaria drugs (Armact, Coartem, Waipa...

Author(s): Adumanya O. C., Uwakwe A. A., Odeghe O. B., Essien E. B. and Okere T. O.

November 2012

Antioxidant screening of ethanolic and aqueous extracts of Organum vulgare L. in-vitro

The present study was envisaged to assess the rationality for the use of traditionally invogue herb Organum vulgare as an anti-oxidant agent. Potential antioxidative activity of O. vulgare was evaluated using various in vitro methods including post mitochondrial supernatant (PMS) and microsomal lipid peroxidation, DNA sugar damage, 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical...

Author(s): Rubina Majid, Latief Ahmad and M. A. Zargar

November 2012

A Biflavonoid and a Carotenoid from Rhus leptodictya: Isolation, Characterization and Antibacterial Properties

Acetone extracts of the leaves of Rhus Leptodictyawere studied for antibacterial activity usingbioautography and micro titre plate assay techniques against four nosocomial bacterial pathogens - Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, andEnterococcus faecalis. A bioassay guided fractionation showed that the activity was concentrated in the carbon tetrachloride fraction. A...

Author(s): Songca SP, Sebothoma C, Samuel BB and Eloff JN

October 2012

Effects of methanol extract of Vernonia amygdalina leaf on survival and some biochemical parameters in acute Trypanosoma brucei brucei infection

The effects of methanol extract of Vernonia amygdalina leaf (chosen from several extracts tested) on survival, parasitaemia, packed cell volume and some biochemical parameters were investigated in acute Trypanosoma brucei brucei infection. Results showed that the extract was relatively safe with median lethal dose, LD50 ≥5000 mg/kg/day. Although none of the extracts tested cured infected...

Author(s): Yusuf, Aminu Bashir, Umar, Ismail Alhaji and Nok, Andrew Jonathan

October 2012

Measurement of cholesterol sub-fractions, high density lipoprotein 2 and high density lipoprotein 3, in HIV infected patients treated with highly active antiretroviral therapy in Burkina Faso

This paper described dyslipidemia caused by the metabolic effects of HIV and exposure to antiretroviral therapy. The aim of this study was to appreciate the interest of the measurement of HDL sub-fractions in the monitoring of human immunodeficiency virus (HIV) infected patients on antiretroviral treatment. A case-control study was carried out on 31 HIV infected before (naive) highly active antiviral therapy (HAART...

Author(s): Jean Sakandé, Josiane B Kaboré, Elie Kabré, Boblwendé Sakandé and Mamadou Sawadogo

June 2012

Heavy metals distribution and lipid profile in the stomach of cow grazed in Akungba-Akoko, Ondo State, Nigeria

Essential oils were obtained by hydro distillation of dried leaves from two kinds of Plectranthus tenuicaulis (Hook f.) J. k. Morton grown in Gabon and were analyzed using GC-FID, GC-MS, 1H and 13C NMR. The main constituent was (R), (E)-6,7-epoxyocimene [(E)-myroxide] (72.2 to 83.8%) with small amounts of (Z)-6,7-epoxyocimene (0.6 to 1.3%), (E) and (Z)-β-ocimene (1.1 to...

Author(s): Bikanga Raphaël, Obame-Engonga Louis-Clément, Agnaniet Huguette, Makani Thomas, Anguile Jean Jacques, Lebibi Jacques, and Menut Chantal

June 2012

Heavy metals distribution and lipid profile in the stomach of cow grazed in Akungba-Akoko, Ondo State, Nigeria

The distribution of heavy metals: manganese, chromium, cadmium, copper, arsenate, iron and lead together with lipid profiles were investigated in the stomach of cow grazed in Akungba-Akoko region of Ondo State, Nigeria. This sample was analyzed using Atomic Absorption Spectrophotometric method (AAS) with wet digestion method. The results showed that the heavy metals concentrations in the stomach of the cows are: Mn...

Author(s): Elekofehinti O. O., Omotuyi I. O., Olaremu A. G. and Abayomi T. G.

May 2012

In vitro anthelmintic potentials of Xylopia aethiopica and Monodora myristica from Nigeria

Monodora myristica and Xylopia aethiopica are two spices that have been traditionally used as a vermifuge in Ayurveda. The main aim of the research work was to investigate the phytochemical constituents of the aqueous, ethanol and methanol extracts of the two spices and the anthelmintic activity of the extracts of their seeds against Eudrilus eugeniae. The four concentrations (10, 20, 50 and 100...

Author(s): Ekeanyanwu R. C. and Etienajirhevwe O. F.

May 2012

Effect of certain insect growth regulators on the lipid content of some tissues of the desert locust Schistocerca gregaria

The present study was carried out to investigate the metabolic effects of pyriproxyfen, tebufenozide or lufenuron on the lipid content in two different tissues: hemolymph and fat body of the early-, mid- and late-aged old nymphs as well as 1- and 4-days old adult females. Hemolymph lipid content of the early-aged nymphs had been subjected to a reducing effect after treatment with high concentration of insect growth...

Author(s): Hamadah Kh.Sh., Ghoneim K.S. and Tanani M.A.

May 2012

Thermogenic response of guinea pig adipocytes to noradrenaline and β3-AR agonists

Brown adipocytes isolated from warm acclimated guinea pig do not respond to noradrenaline (NA) in spite of their marked thermogenic response in vivo. In contrast, in cold-acclimated guinea pigs, isolated brown adipocytes show substantial increase in capacity for a thermogenic response to NA. Chronic stimulation with a β3-AR agonist increased insulin-sensitivity of brown adipose tissue (BAT) in the guinea pig....

Author(s): Ghorbani Masoud and Mehdi Shafiee Ardestani

May 2012

Intraspecific diversity of Egyptian and foreign new lines of chickpea based on Sodium dodecyl sulfate polyacrylamide gel electrophoresis (SDS-PAGE) and isozyme markers

Four Egyptian and 21 foreign new lines of kabuli chickpea (Cicer arietinum L.) were analyzed by using biochemical molecular markers to gain insight into the genetic diversity between accessions. Polyacrylamide gel electrophoresis (PAGE) was applied on the total soluble seed proteins by using sodium dodecyl sulphate (SDS) and five isozyme systems to examine the storage and functional components, respectively. The storage...

Author(s): Maged Mahmoud Abou-El-enain and Shawkat Mahmoud Ahmed

April 2012

Effect of vitrifying solutions, ethylene glycol and 1, 2-propandiol, on intracellular K+ and lactate dehydrogenase (LDH) of hepatocytes in primary culture

Shortage of donor liver tissue for the isolation of hepatocytes requires the development of improved cryopreservation techniques for long-term storage of these cells for more efficient use. The aim of this study is to compare two cryoprotectants for preserving living cells in culture by vitrification. The viability of hepatocytes after cryopreservation was determined by the intracellular concentration of potassium...

Author(s): Diallo Mouhamadou, Nguer Cheikh Momar, Gueye Papa El Hadji Omar, Ndongo Souhaibou, Sarr Ousmane and Mboup Souleymane

April 2012

Toxicological investigation of aqueous leaf extract of Calotropis procera (Ait.) R. Br. in Wister albino rats

The pathological changes due to the oral administration of the aqueous extract of the leaves ofCalotropis procera were studied in rats over a period of sixty days. The leaf extract was administered orally to rats in three groups receiving doses of 500, 1000 and 1500 mg/kg. The fourth group served as a control and received distilled water only. Result showed that, oral administration of the aqueous extract...

Author(s): Mohammed A., Ibrahim S. I. and Bilbis L. S.,

April 2012

In-vitro assessment of antioxidant potential and phenolic capacity of Temnocalyx obovatus leaves

Temnocalyx obovatus is widely found in many areas in Zimbabwe, Nigeria and Zambia where it is used to treat a variety of ailments. Phenolic compounds in T. obovatus assessed by Folin-Ciocalteu method varied from 1.18 to 2.89 mg tannic acid g-1. Acetone extract showed the greatest flavonoids, flavonols and proanthocyanidins content 5.12, 4.13 and 3.07 mg catechin g-1respectively. 2,...

Author(s): P. Dzomba, E. Togarepi and C. Mahamadi

April 2012

Effect of boiling on the phytochemical constituents and antioxidant properties of African pear Dacryodes edulis seeds in vitro

  African pear, Dacryodes edulis, seed extract has been used for the treatment of ailments in traditional medicine. However, the effect of boiling on its antioxidant properties is still poorly understood. Therefore, the present study investigates the effect of boiling on the antioxidant properties of D. edulis seed extract using in vitro parameters such as free radical scavenging ability against 2, 2- diphenyl...

Author(s): T. Ogunmoyole, I. J. Kade, O. D. Johnson and O. J. Makun

March 2012

Levels of matrix metalloproteinases (MMPs) in tear fluid of mustard gas exposed patients with chronic dry-eye symptoms

The purpose of this study is to compare the levels of MMP-1, 2, 8, 9 in tear fluids of people exposed to mustard gas in the war between Iraq and Iran who had the chronic dry-eye symptoms compared to the normal group. In this study, 25 of the patients who were exposed to mustard gas and had chronic dry eye symptoms were compared to 25 patients as control group; consisting of 25 people who had common chronic dry eye...

Author(s): Reza Haji Hosseini and Malek Ashtar Esfandiary

March 2012

Antioxidant capacity of bioactive compounds extracted from selected wild and domesticated cereals of Zimbabwe

Bioactive compounds were extracted from 6 wild and 4 domesticated cereal grains of Zimbabwe, using 50% methanol with the aim of testing their capability to prevent phospholipid peroxidation and β-carotene bleaching. The highest yield of phenolic compounds was obtained from Eleusine indica (a wild cereal) with 7.16 mg GA/100 mg sample, while the least yield was obtained from Amaranthus...

Author(s): Kudakwashe Chitindingu, Jill J. F. Chitindingu, Mudadi A. N. Benhura, Amos Marume, Isaac Mutingwende, Michael Bhebhe and Maud Muchuweti

March 2012

Effects of harvest time and cultivar on yield and physical properties fibers of kenaf (Hibiscus cannabinus L.)

Kenaf (Hibiscus cannabinus L.) is an annual non wood plant which has shown great potential as an alternative source of papermaking fiber. No information is available on kenaf cultivation in south-Iran in spite of the need to replace imported long fibers through local production of alternative sources. The purpose of this research is to investigate the effect of kenaf cultivars and harvest times on component yield...

Author(s): Jalal Shakhes, Farhad Zeinaly, Morteza A. B Marandi and Tayebe Saghafi

March 2012

Chemical composition and in vitro antioxidant, cytotoxicity activities of Zingiber officinale Roscoe essential oil

This study was designed to examine the in vitro antioxidant and cytotoxicity activities of Zingiber officinale Roscoe (ginger) rhizome essential oil. GC-MS analysis of the essential oil resulted in the identification of 7 compounds, representing 90.06% of the oil, the major constituents were described as α-zingiberene (52.35%), β-pinene (14.20%) and β-sesquiphellandrene (12.11%). The...

Author(s): Wei Wang, Lin Zhang, Nan Li, and Yuangang Zu,

February 2012

Comparative phenolic profile of Persian walnut (Juglans regia L.) leaves cultivars grown in Iran

In this study Walnut leaves from 11 different cultivars (Mayette, Fernor, Mellanaise, Elit, Orientis, Lara, Hartley, Franquette, Parisienne, Arco and Marbot) were studied for their phenolic compounds. The evolution of major phenolic compounds amounts was monitored from May to September. Two extractive procedures were assayed and the best results were obtained using acidified water (pH 2) and a solid phase...

Author(s): Amir Jalili and Asra Sadeghzade

February 2012

Bacteriological characterization of snacks sold in Rivers State University of Science and Technology, Port Harcourt, Nigeria

Two types of pastry snacks (Moin-moin and Buns) were bought from four different hawkers in the Rivers State University of Science and Technology, Port Harcourt, from four locations viz. Student Residential area, Faculty of Science, Faculty of Engineering and the Old Administrative area. Ten representative bacterial isolates from each of the snacks from the locations were tentatively identified separately from...

Author(s): Lovet T. Kigigha and Henry C. Uge

February 2012

Effect of essential oil of the leaves of Eucalyptus globulus on heamatological parameters of wistar rats

The study was designed to evaluate the effect of essential oil extract of Eucalyptus globulus on haematological parameters of wistar rats. Twenty-five adult wistar rats weighing between 80 to 130 g were used. The rats were divided into five groups; with group one as the control group. Increasing doses (12.5, 25.0, 50.0, 72.5 mg/ml) of the extract were administered orally daily to the other four groups for a...

Author(s): OYESOMI, Tajudeen Oyesina, AJAO, Moyosore Salihu, OLAYAKI, luquman Aribidesiand ADEKOMI, Damilare Adedayo

February 2012

Unutilized energy reserves and mineral contents of fibroid tissues suggesting perturbed membrane transport processes

Compositions of intramural uterine fibroid (IUF) and subserous uterine fibroid (SUF) tissues were studied. Results showed that IUF and SUF, respectively, contained (%) 77.26 ± 0.05 and 77.49 ± 0.02 moisture and 22.74 ± 0.05 and 22.52 ± 0.02 dry matter, on wet-weight basis. Their respective moisture, crude fat, crude protein, ash and total carbohydrates (%) were 4.67 ± 0.05 and 4.38...

Author(s): Ibegbulem C. O., Agha N. C. and Emeka-Nwabunnia I.

January 2012

Effect of electromagnetic field on acetylcholinesterase activity: In vitro study

The in vitro effects of extremely low frequency (ELF)-electromagnetic field (EMF) (frequencies of 50, 100, 217 Hz, induction 300 µT) on the structure and activity of acetylcholinesterase (AChE) was investigated. AChE activity was measured with UV-vis spectroscopy. Circular dichroism spectroscopy and fluorescence spectroscopy were used for investigating the secondary and tertiary structure of enzyme. The...

Author(s): Ezzatollah Fathi and Raheleh Farahzadi

January 2012

Matrix metalloproteinases activity in fibrosarcoma Wehi-164 cells

Fibrosarcoma is a malignant disorder of fibroblasts and extremely metastatic cancer. Angiogenesis plays an important role in metastasis. Several factors including matrix metalloproteinases (MMPs) involve in angiogenesis. MMPs are a large group of endopeptidases which degredate the extracellular matrix. The present study was conducted to evaluate the patterns of MMP-2/MMP-9 activity in Wehi-164 cells in vitro....

Author(s): Fatemeh Hajighasemi and Fatemeh Rezaeian

January 2012

The significance of artemisinin in roll back malaria partnership programmes and cancer therapy

The role of the natural product, artemisinin, is discussed, with a view to elucidating its importance as an antimalarial, essential to sustainable global development, especially in the health and welfare industry. An estimated 243 million cases of malaria led to an estimated 863,000 deaths in 2008. The Roll Back Malaria (RBM) Partnership is a global network for co-ordinated action against malaria, launched in 1998 by...

Author(s): Obimba, Kelechukwu Clarence

January 2012

Maternal oxidative stress and enzymatic antioxidant status in premature rupture of membranes

Premature rupture of the fetal membrane is a major cause of preterm birth and it is associated with infant morbidity. To examine the relationship between maternal oxidative stress (OS) and antioxidant statue and premature rupture of membranes (PROM). 30 pregnant women with PROM and 30 normal pregnant women were compared for maternal malonaldihyde concentration, erythrocyte glutathione (GSH) concentration, glutathione...

Author(s): Jafar Maleki, Ladan Haghighi, Mohsen Korani, Soudabeh Fallah, Mohsen Firozrai and Morteza Seifi

January 2012

The significance of artemisinin in roll back malaria partnership programmes and cancer therapy

The role of the natural product, artemisinin, is discussed, with a view to elucidating its importance as an antimalarial, essential to sustainable global development, especially in the health and welfare industry. An estimated 243 million cases of malaria led to an estimated 863,000 deaths in 2008. The Roll Back Malaria (RBM) Partnership is a global network for co-ordinated action against malaria, launched in 1998 by...

Author(s): Obimba, Kelechukwu Clarence

January 2012

Maternal oxidative stress and enzymatic antioxidant status in premature rupture of membranes

Premature rupture of the fetal membrane is a major cause of preterm birth and it is associated with infant morbidity. To examine the relationship between maternal oxidative stress (OS) and antioxidant statue and premature rupture of membranes (PROM). 30 pregnant women with PROM and 30 normal pregnant women were compared for maternal malonaldihyde concentration, erythrocyte glutathione (GSH) concentration, glutathione...

Author(s): Jafar Maleki, Ladan Haghighi, Mohsen Korani, Soudabeh Fallah, Mohsen Firozrai and Morteza Seifi

December 2011

Screening of antioxidant activity, total phenolics and gas chromatography-mass spectrophotometer (GC-MS) study of ethanolic extract of Aporosa lindleyana Baill

The present study was carried out for the identification of phytochemicals present in the roots ofAporosa lindleyana and also to evaluate the total phenol, total flavonoids and antioxidant activity. Total phenol was carried out by Folin Ciocalteu method and the phenolic content was 31.20 mg/100 g of gallic acid equivalent (GE) and the flavonoid content was 203.10±0.9. Antioxidant activity was evaluated by...

Author(s): S. Ramakrishnan and R. Venkataraman

  • Article Number: 3E134BF12944

December 2011

Alterations in the biochemical components and photosynthetic pigments of mulberry (Morus Spp.) attacked by leaf – roller (Diaphania pulverulentalis) pest

Leaf roller (Diaphania pulverulentalis Hampson) is a serious pest of mulberry (Morus alba L.), which is the sole food for silkworm – Bombyx mori L. It attacks the tender leaves of the host causing considerable damage which alters the leaf quality. An attempt was made to know the changes in the biochemical components (free amino acids, total soluble proteins, total reducing sugars, total soluble...

Author(s): A. Mahadeva and V. Nagaveni

  • Article Number: 76C9F1A12954

December 2011

The apoptotic and cytotoxic effects of Polygonum avicular extract on Hela-S cervical cancer cell line

Cervical cancer is the second main cause of cancer leading death in women. Therefore, targeting it, preferably with natural compounds derived from medicinal plant such as Polygonum avicular as an herbal extract have astringent properties. Herbal medicines in all regions of the developing world are widely used. Unlike the heavy use, there are very little information about the health and efficiency of the treatment by...

Author(s): Rahmati Mohammad, Bannazadeh Hossein, Fazli Davood, Tahmasebzadeh Farnaz, Farrokhi Ali and Rasmi Yusef

  • Article Number: EB92BD812962

November 2011

Anti-atherogenic effects of supplementation with vitamin B6 (Pyridoxine) in albino rats

Elevation of serum lipids have been implicated to predispose to cardiovascular disorders which includes hypertension, stroke, atherosclerosis etc. Various studies have reported links between supplementation with vitamin B complex and reduction in oxidative stress and inflammatory reactions, two events associated with cardiovascular disorders. Data on possible direct regulation on lipid profile by vitamin B6 is very...

Author(s): Adekunle Adeniran S. and Adedeji Adebayo L.

  • Article Number: DEDA70112912

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