African Journal of
Biochemistry Research

  • Abbreviation: Afr. J. Biochem. Res.
  • Language: English
  • ISSN: 1996-0778
  • DOI: 10.5897/AJBR
  • Start Year: 2007
  • Published Articles: 407

AJBR Articles

Effects of n-butanol fraction of Gongronema latifolium leave extract on some biochemical parameters in CCl4- induced oxidative damage in Wistar albino rats

February 2014

Effects of n-butanol fraction of Gongronema latifolium leave extract on some biochemical parameters in carbon tetrachloride-induced oxidative damage in Wistar albino rats were assessed. Fifty-four (54) Wister albino rats were divided into treatment group and LD50 groups. Group A (normal control) was given feed and water, Group B (vehicle control) was injected with olive oil intraperitoneally, while the rest groups (C,...

Author(s): Okpala, J. C., Sani, I., Abdullahi, R., Ifedilichukwu, H. N. and Igwe, J. C.

Treatment of lead-poisoned rats through oral administration of palm oil extracts

February 2014

The palm fruit (Elaies guineensis) is the source of palmitic-oleic rich semi-solid fat and fat-soluble minor components, made up of vitamin E (tocopherols and tocotrienols), carotenoids and phytosterols. This study was in two parts. Firstly, it examined the effects of palm oil fractionation methods on recovery and concentration of carotenes, tocopherols and tocotrienols which are known to have nutritional and medicinal...

Author(s): Peter Twumasi, Kwabena Nsiah and Emmanuel Yeboah Osei

Serum lipids and oxidized low density lipoprotein levels in sickle cell disease: Assessment and pathobiological significance

February 2014

One hundred and eighteen (118) subjects aged 15 to 36 years divided into control subjects (AA n = 42), heterozygous sickle cell patients (AS n = 33) and homozygous sickle cell patients (SS n = 43) were investigated for a lipid profile including the measurement of oxidized low density lipoprotein (LDL) to assess the risk of early atherosclerosis in sickle cell disease. The results show that total, high density...

Author(s): Diatta Alassane, Cissé Fatou, Guèye Tall Fatou, Diallo Fatou, Touré Fall Awa Oumar, Sarr Gaston Ndéné, Lopez Sall Philomène, Sall Niama Diop and Touré Méïssa

Extraction and comparison of fibrolytic enzyme additives from gut of 11 ungulates

February 2014

Microbial populations in herbivores gut attack, degrade and ferment structural carbohydrates in forage cell walls, producing volatile fatty acids and microbial proteins for the host. Exocellulases, endocellulases and cellobiases are the major cellulolytic enzymes while hemicellulase (xylanase) exposes cellulose for fermentation. This study aimed to isolate proteins that hydrolyse fibre or assist fibrolysis in any way...

Author(s): Fabian Nde Fon, Ignatius Verla Nsahlai and Peter Frank Scogings

Collaborative effects of some anti-diabetic plants on the liver marker enzymes of diabetic rats

January 2014

The leaves of Psidium guajava, Anacardium occidentale, Eucalyptus globulus and fruits of Xylopia aethiopica are used in the management of diabetes mellitus. The phytochemical constituents as well as the acute toxicity of the combined chloroform extracts (A. occidentale + E. globulus and P. guajava + X. aethiopica) and their effects (at graded doses of 100 and 250 mg/kg body weight each) on the activities of alanine...

Author(s): GOMETI Ajiroghene S., OGUGUA Victor N., ODO Christian E., JOSHUA Parker E. and OBI Kelechi N.

The composition of fatty acids stored in liver, muscle and fat tissues of the African lungfish Protopterus annectens (Owen, 1839)

January 2014

The composition and profile (%) of fatty acids stored in liver, muscle, and fat tissues of the fresh-water African lungfish Protopterus annectens were determined by gas chromatography. High content of total fatty acids (TFA) was found in fat (62.06 ± 3.4 g/100 g) followed by liver (50.68 ± 4.72 g/100 g) and muscle tissues (10.9 ± 0.81 g/100 g). Saturated fatty acids (SFA) formed 72.9% TFA in the...

Author(s): H. A. Elagba Mohamed and Jamal N. Al-Sabahi

A microassay for quantification of 2,2-diphenyl-1-picrylhydracyl (DPPH) free radical scavenging

January 2014

Polyphenols are the second largest abundant organic molecules in nature. One of the principal reported biological activities is the antioxidant capacity. 2,2-Diphenyl-1-picrylhydracyl (DPPH) method has been used to quantify polyphenols antioxidant activity in many different products with reproducible and reliable results. We proposed and validated a methodology to analyze this antioxidant activity with smaller amount of...

Author(s): Norma P. Meléndez , Virginia Nevárez-Moorillón, Raúl Rodríguez-Herrera, José C. Espinoza and Cristóbal N. Aguilar

The protective role of oral consumption of N-acetyl cysteine during a single session of exhaustive exercise in untrained subjects

January 2014

The aim of the current study was to verify the effect of N-acetyl cysteine (NAC) supplementation on markers of oxidative stress and inflammatory response during a single session of exhaustive exercise. In a randomized placebo-controlled double-blind clinical trial, thirty healthy, untrained young males and females with a mean age of 21.33±2.39 years, weight of 59.63± 9.24 kg and height of...

Author(s): Iranpour D, Movahed ALI, Goudarzi A, Tarverdizadeh Bahman, Akbarzadeh Samad, Motamed Niloufar, Pakdel Farhad, Hagian Ali Akbar, Seyedian Ramin, Vahdi Saeid and Tahmasebi Rahim

Proximate composition of Rastrineobola argentea (Dagaa) of Lake Victoria-Kenya

January 2014

Proximate composition analysis for crude lipid content, crude protein content, moisture content, total ash content and dry weight of Dagaa (Rastrineobola argentea): a small pelagic fish which constitutes one of the main fish species in Lake Victoria was determined from selected beaches: Paga, Dunga, Rota, Usari and Nduru around Lake Victoria-Kenya. This was done with a view to provide nutritional data to guide food...

Author(s): Ogonda, Lydia Awuor, Muge, Edward Kirwa, Mulaa, Francis Jackim and Mbatia, Betty Nyambura

Ferric reducing antioxidant power and total phenols in Cordia africana fruit

December 2013

Antioxidants are beneficial compounds found in a lot of foods. Cordia africana (Lam.) is a small fruit eaten all over Tigray and other parts of Ethiopia. The fruit was tested for its antioxidant content using the ferric reducing antioxidant power (FRAP) assay and total phenols (TP) measured with Folin Ciocalteu`s reagent, across four different agroecological zones and three land use classes in Tigray. The average FRAP...

Author(s): Tewolde-Berhan Sarah, Remberg Siv Fagertun, Abegaz Kebede, Narvhus Judith, Abay Fetien and Wicklund Trude

Effects of fungal (Lachnocladium spp.) pretreatment on nutrient and antinutrient composition of corn cobs

December 2013

The nutritive value of corn cob following pretreatment by fermentation with fungal species of Lachnocladium spp. was investigated. Corn cob was milled and subjected to incubation with fungal species for a period of one week. Significant increase (p<0.05) in protein, ash and some mineral elements were observed. Calcium, magnesium, zinc and sodium content were observed to be higher in fermented cobs while significant...

Author(s): A. Olagunju, E. Onyike, A. Muhammad, S. Aliyu and A. S. Abdullahi

Impact of Anthocleista vogelii root bark ethanolic extract on weight reduction in high carbohydrate diet induced obesity in male wistar rats

December 2013

Obesity increases the risk of developing a number of diseases such as insulin resistance, type 2 diabetes, hypertension, hypercholesterolemia, stroke and heart attack. The aim of this study was to investigate the impact of ethanolic root bark extract of Anthocleista vogelii on weight reduction in high carbohydrate diet (HCD) induced obesity in male Wistar rats. Thirty male Wistar rats were housed in three...

Author(s): Anyanwu, G. O., Onyeneke, E. C., Usunobun, U. and Adegbegi, A. J.

Physicochemical parameters and selected heavy metals assessment of drinking water at the students’ residences of the Nigerian Premier University

November 2013

Heavy metals contamination of drinking water is an important health risk factor due to the attendant toxic effect linked to it. We therefore assessed the quality of borehole, tap and well water samples in each of the seven students’ residential areas of University of Ibadan. Physicochemical parameters of the water samples including pH, turbidity, total suspended solids (TSS), total dissolved solids (TDS), as well...

Author(s): O.A Odunola, M. A. Gbadegesin, S.E. Owumi, K.A. Akinwumi and B. Ogunbiyi

Production of tannase and gallic acid by Aspergillus tamarii in submerged and solid state cultures

November 2013

The hydrolytic enzyme, tannase and the antioxidant phenolic compound, gallic acid are useful in many biotechnological processes especially in food and pharmaceutical areas. The purpose of this study was to evaluate the production of tannase and gallic acid by Aspergillus tamarii developed in submerged and solid state cultures using tannic acid as substrate. In submerged cultures, maximal tannase activity (20,400...

Author(s): Andrea Miura da Costa, Cristina Giatti Marques de Souza, Adelar Bracht, Marina Kimiko Kadowaki, Aline Cristine da Silva de Souza, Roselene Ferreira Oliveira and Rosane Marina Peralta

Marine fungal metabolites as a rich source of bioactive compounds

November 2013

This paper reviews the recent results of bioactive compounds derived from marine fungi, which are highly diversified and are less explored. Researchers are showing keen interest in isolating novel bioactive compounds with clinical applications. Hence, here we discussed most of the bioactive compounds isolated from marine derived fungi and their possible roles in various efficient biological activities. Key words:...

Author(s): J. Swathi, K. Narendra, K. M. Sowjanya and A. Krishna Satya

Effect of combined use of Ocimum gratissimum and Vernonia amygdalina extract on the activity of angiotensin converting enzyme, hypolipidemic and antioxidant parameters in streptozotocin-induced diabetic rats

October 2013

  This study was aimed at investigating the angiotensin converting enzyme (ACE) inhibitory effect, hypolidemic and antioxidant properties of combined extract of Occimum gratissimum andVernonia amygdalina in streptozotocin-induced diabetic rats. Thirty (30) apparently healthy male Wistar rats were grouped into: control, diabetic, diabetic + insulin, diabetic + 100 mg/kg and diabetic + 250 mg/kg...

Author(s): Abdulazeez Mansurah A., Ibrahim Kassim, Bulus Kenpia, Babvoshia Hope B. and Abdullahi, Yusuf

Effect of oestrous cycle on serum electrolytes and liver enzymes in Red Sokoto goats

October 2013

  This study was carried out to determine changes in serum electrolytes and liver enzymes during the oestrous cycle in Red Sokoto goats. Eleven (11) apparently healthy Red Sokoto goats were synchronized with a single injection of 7.5 mg of PGF2α. The goats were bled via jugular venipuncture in oestrus or late oestrus, metoestrus/early dioestrus, mid-dioestrus and late dioestrus/proestrus. Mean serum...

Author(s): Yaqub, L. S., Kawu, M. U., Ayo, J. O., Ambali, S. F., Habibu, B.

The effects of Yucca schidigera on blood glucose and lipid levels in diabetic rats

October 2013

  The aim of this study was to investigate the effects of Yucca schidigera (YSE) on lipid peroxidation and some biochemical parameters in streptozotocin-induced (STZ) diabetic rats. Four groups of seven rats each were used in this study. Supplementation period was three weeks. The groups were: I. control group (C), normal feed; II. diabetic (DM-YSE), normal feed plus YSE 100 ppm/kg; III. diabetic...

Author(s):   Nuray OZTASAN

Phosphotidylcholine as a new strategy in biocompatible material

September 2013

  Biomaterial has a wide variety of usages in medicine and chemistry. The biomaterials used in medicine and chemistry are often polymers. Polymers used as biomaterial must be compatible to the environment and they must not be poisonous and in case they are broken down they must not provide poisonous products in biological environment. The biomaterial used for each case has certain and specific chemical and...

Author(s): Reihaneh Sabbaghzadeh

Optimization of metalloprotease production by Eupenicillium javanicum in both solid state and submerged bioprocesses

September 2013

  Proteases are enzymes that have great importance in industries and can be produced through bioprocess by microorganisms. Changes in parameters can influence the production rate of these enzymes. The current study evaluated the influence of these parameters on the production of proteases by the fungus Eupenicillium javanicum under both solid state bioprocess (SSB) and submerged bioprocess (SmB), and...

Author(s): Youssef Ali Abou Hamin Neto, Cristina Maria de Souza Motta and Hamilton Cabral

The changes of fatty acid composition in sun dried, oven dried and frozen hake (Merluccius merluccius) and sardinella (Sardinella aurita)

September 2013

  The fatty acid composition and fat quality alteration of the round sardinella (Sardinella aurita) and the European hake (Merluccius merluccius) fillets during the frozen storage (-30°C), sun drying and controlled oven drying (temperature = 60°C, air velocity = 2 m/s and relative humidity = 20%) were investigated. Results show that the fresh fillets of the S. aurita and M....

Author(s): Khaoula Telahigue, Tarek Hajji, Imen Rabeh and M’hamed El Cafsi.

An evaluation of antioxidants and oxidative stress in Iraqi patients with thyroid gland dysfunction

September 2013

The present study evaluates the effects of hypothyroidism and hyperthyroidism states on antioxidant vitamins (A, E, C, β-carotene) and uric acid in Iraqi patients before treatment. Lipid peroxidation, an index of oxidative stress was elevated in hyperthyroidism but reduced in hypothyroidism patients as compared to control. The results showed a highly significant decrease in the sera levels of Vitamins A, E...

Author(s): Salwa H. N. Al-Rubae&#;i and Abass K. Al-Musawi

Tea Artemisia annua inhibits Plasmodium falciparum isolates collected in Pikine, Senegal

August 2013

  Malaria is a major scourge of most countries in Africa which continues to defy science and technology. Several medicinal plants are traditionally used for the treatment of malaria and other protozoa infections. We aimed to assess by the Double-site Enzyme-linked Lactate dehydrogenase enzyme Immuno-detection (DELI) test for the first time in Senegal, Plasmodium falciparum isolates in...

Author(s): Gueye Papa El hadji Omar, Diallo Mouhamadou, Deme Awa Bineta, Badiane Aida Sadikh, Dior Diop Mare, Ahouidi Ambroise, Abdoul Aziz Ndiaye, Dieng Thérése, Lutgen Pierre, Mboup Souleymane and Sarr Ousmane

A pentacyclic triterpene from the leaves of Combretum collinum Fresen showing antibacterial properties against Staphylococcus aureus

August 2013

  Leaf extracts of six different plants, many of which are used by traditional healers, were screened for antibacterial activity. These include Adina microcephaha, Combretum aurea,Combretum bracteosam, Combretum collinum, Filicium decipiens and Ficus moraceae. The highest mass of 118 mg was extracted with acetone from F. decipiens and the lowest mass of 18 mg was extracted...

Author(s): Songca S. P., Ramurafhi E. and Oluwafemi O. S.

Association of SOD2 gene polymorphism with noise induced hearing loss in textile industry employees

August 2013

  Noise exposure leads to hearing loss in industrial workers due to release of superoxide anions which damage cochlear epithelium in the ear. These free radicals are regulated by superoxide dismutase 2 (SOD2) and polymorphism in this gene may abet in predisposition to noise induced hearing loss (NIHL). The current study describes prevalence of polymorphism at two different loci...

Author(s): Afshan Iqbal, Mamoona Naz, Ferhana Hussain, Mahjabeen Saleem and Beenish Kashif Hashmi

Changes in the tissue antioxidant enzyme activities of palm weevil (Rynchophorous phoenicis) larva by the action of 2, 2-dichlorovinyl dimethyl phosphate

August 2013

  The aim of this study was to determine the changes caused by the action of 2,2-dichlorovinyl dimethylphosphate (DDVP) on the three tissues, fat body (FB), gut (GT) and head (H), and the  antioxidant enzymes of African black palm weevil, Rynchophorous phoenicis (Coleoptera: Curculionidae) larva. Larvae of R. phoenics were injected with varied concentrations (0 to 0.66 µg...

Author(s): Olufemi Bamidele, Joshua Ajele, Ayodele Kolawole and Akinkuolere Oluwafemi

Protein sparing effects of carbohydrate in African catfish, Clarias gariepinus

July 2013

  Feeding trial was conducted to examine the protein sparing effects of carbohydrate in Clarias gariepinus, an attempt to reduce the feed cost. C. gariepinus fingerlings mean weights of 8.32 ±0.04 g were randomly allotted into a group of 15 fishes per tank in triplicate of 10 treatments. They were fed on nine experimental diets and a commercial Catfish Reference Diet (CRD). The formulated...

Author(s): Orire A. M. and Sadiku S. O. E.

Seed oil diversity of Ethiopian linseed (Linum usitatissimum L.) landraces accessions and some exotic cultivars

July 2013

  Keeping in view, lack  of adequate information on  genetic  diversity  in  the  Ethiopian linseed (Linum ustatisimum L.) landraces on one hand and its immense importance in the agricultural systems on the other hand in Ethiopia, 49 accessions collected from five regions of Ethiopia together  with fifteen exotic cultivars were  used  in  this ...

Author(s): Mulusew Fikere, Firew Mekbib and Adugna Wakjira

Effects of organic manures on the physicochemical properties of crude oil polluted soils

July 2013

  The impact of crude oil pollution on the edaphic physicochemical parameters and the influence of incorporation of different types of organic manures in the polluted soils were investigated. The factorial set of treatments were six levels of crude oil pollution (0, 30, 60, 90, 120 and 150 ml), while amendment treatments were done after two weeks of pollution treatment, using the following organic manures:...

Author(s): N. A. Obasi, Eberechukwu Eze, D. I. Anyanwu and U. C. Okorie

Stability study of smoked fish, horse mackerel (Trachurus trachurus) by different methods and storage at room temperature

July 2013

  The present study assessed the effect of hot smoke using wood and charcoal dry heat on keeping quality of Trachurus trachurus fish fillet, skin, head and bones (SHB). T. trachurus was smoked using the altona kiln at 80 to 105°C for eight hours, placed in cain woven baskets to cool off, packaged in sealed transparent polythene bags and left on shelf for 7 days at ambient...

Author(s): O. T. Adeyemi, O. O. Osilesi, F. Onajobi, O. Adebawo and A. J. Afolayan

The effect of quinine on myeloperoxidase activities in the neutrophil

July 2013

  Quinine has been known to impair the functions of polymorphonuclear neutrophils (PMN). Myeloperoxidase is the most abundant enzyme found in the neutrophil. The enzyme is known to catalyse the formation of hypochloride from hydrogen peroxide and chloride, as part of the normal cellular defence system in the polymorphonuclear neutrophil. This study was carried out to investigate the effect of quinine on...

Author(s): J. B. MINARI, O. B. OLOYEDE and T. A. OLADIJI

Study of interaction between lysozyme-aminoglycosides and penicillin

June 2013

  The interaction between aminoglycosides-lysozyme and penicillin-lysozyme was studied by using UV and IR spectroscopy. The study was started with the purification of lysozyme from hen, quail, duck and pigeon and designated as HEWL, QEWL, DEWL and PEWL, respectively. Aminoglycosides (kanamycin and streptomycin) and penicillin (ampicillin) interactions with lysozyme were explored in this investigation. The study...

Author(s): Anand Krishnamurthy, Sudarsanam D, Anantharamanan R. and Najmeh Alirezaie

Effects of water stress on physiological processes and yield attributes of different mungbean (L.) varieties

June 2013

  In order to investigate the effect of water stress on Mungbean varieties and its physiological responses to yield, a field experiment was carried out according to split plot design with twenty treatments combination and three replications during 2010 and 2011 at Crop Research Centre of Sardar Vallabhbhai Patel University of Agriculture and Technology, Meerut (Uttar Pradesh). The results indicated that drought...

Author(s): R.K. Naresh, Purushottam, S.P.Singh, Ashish Dwivedi and Vineet Kumar

Hot water and molybdenum dips: The case of antioxidant assays in lemon flavedo during cold storage

May 2013

  Antioxidants are part of the plant’s defense system, protecting tissue against oxidative stress. In citrus fruit, oxidative stress can occur during extended cold storage ultimately result in chilling injury. Citrus fruit contain certain rind antioxidants which occur in different forms (lipophilic and hydrophilic). Previous studies demonstrated a synergistic relationship between hot water dips (HWD) and...

Author(s): Nhlanhla Mathaba, and Isa Bertling

Effects of sub-chronic exposure to moderate intensity static magnetic field (SMF) on oxidative stress parameters of male rats

May 2013

  Increasing exposure to electromagnetic fields has become inevitable for people living in industrialized environments. Magnetic fields can increase the production of free radicals; reports also suggest that extremely low frequency magnetic fields (ELF-MF) can increase free radical life-span. This study evaluated the effects of moderate intensity static magnetic field (SMF) (56 Hz, 41 mT, 6 h/day) on the...

Author(s): A. A. Omonkhua and D. D. Abajingin

Biochemical markers of ethnic Pakistanis: A correlation between genetic-aloofness and nutritional status affecting average age of each group

April 2013

  The nutritional status and ethnic-aloofness (non mixed genomes owing to lack of cross marriages) might have direct impact on the average age and quality of health of the individuals belonging to different racial groupings. North Western region of Balochistan around Quetta, Pakistan, has diverse ethnic populations which afford a unique genomic pattern in addition to specific life style, pattern of eating,...

Author(s): Abrar Hussain Khan, Muhammad Azhar Sherkheli, Muhammad Asif, Mahmood Rasool  and Agha Muhammad Raza

Tomato supplement ameliorates castration-induced oxidative stress in the rat

April 2013

  Castration has previously been shown to induce oxidative stress. Previous studies have shown tomato to be a potent anti-oxidant which reduces oxidative stress in many disease conditions. However, the likely role of tomato in ameliorating castration-induced oxidative stress has not been studied and was of interest to us. The present study looked into the effect of tomato supplement on the plasma level of...

Author(s): Ayobami Oladele Afolabi, Oluwatosin Oluwaseun Osho and Isiaka Abdullateef Alagbonsi

Comparative osmotic fragility of three erythrocyte genotypes (HbAA, HbAS and HbSS) of male participants administered with five antimalarial drugs

March 2013

n vivo study was carried out to ascertain the mean corpuscular fragility (MCF) index and corresponding stability of three erythrocyte genotypes (HbAA, HbAS and HbSS) before (control; t = 0 h) and after (tests; that is, at t = 3, 6 and 18 h) five (5) antimalarial drugs (FansidarTM, HalfanTM, Quinine, CoartemTM, and Chloroquine phosphate) were administered to male participants. Clinically confirmed healthy...

Author(s): P. C. Chikezie, A. A. Uwakwe and C.C. Monago

Oxalate metabolism by Sclerotinia sclerotiorum, a fungal pathogen in soybeans

February 2013

  Pathogenesis of Sclerotinia sclerotiorum mainly depends on production of oxalate (Lib.) de Bary, but the mechanism by which the oxalate is produced is not well understood. Control of Sclerotinia stem rot (SSR) in soybean which is caused by this ubiquitous phytopathogenic fungus requires the knowledge of oxalate synthesis by S. sclerotiorum. Nine isolates from infected soybeans and soils were...

Author(s): Mbiri A., Gatebe E., Ndung’u M., Kariuki W. and Mwangi E.

Nutrigenomic studies of orange juice and vitamin c on gene expressions in neuronal tissues of Sprague Dawley rats

February 2013

  Nutrigenomics, a nascent field in nutrition and molecular biology plays a pivotal role in understanding the influence of bioactive dietary components on the structure, integrity and functions of the genome. In this study, the comparative effects of vitamin C (Vit C) and Nigerian local orange juice on the gene expression levels of superoxide dismutase (sod), tumour necrosis factor receptor...

Author(s): Osaretin Albert T.  Ebuehi, Yusuf Salami, Ayorinde B. James and Imelda N. Mgbeadichie

Plasma concentration of acylated ghrelin in patients with Alzheimer’s disease

January 2013

  Ghrelin is a hormone produced in the stomach and tightly linked to the regulation of energy balance and cognitive processes. It may be altered in Alzheimer’s disease (AD), a dementia syndrome markedly influenced by metabolic diseases. The aim of this study was to evaluate the changes in the plasma concentration of acylated ghrelin in patients with AD. The study included 71 people 37 in the case...

Author(s): Akbarzadeh S, Yusefi F, Jafari SM, Khosravizadegan F, Moula A, Salimipour H, Eghbali SS, Motamed N, Hajian N, Rahbar A, Abdi MR, Hazrati S and Movahed A

Serum ghrelin levels in Syrian obese patients with diabetes mellitus type II

January 2013

  The serum ghrelin levels had been studied in three groups of subjects׃ First group was normal weight (11 men and 9 women), non obese, non diabetic, 38 ± 12 years old, with BMI mean about 23.8 kg/m2 and did not take any drugs. The second group was overweight (18 men and 13 women), non diabetic, 40.6 ± 9.9 years old, with BMI mean about 36.34 kg/m2. This group was apparently healthy and...

Author(s): Moayad A. Saad, Younes M. Kabalan and Faizah A. Al-Quobaili

Effects of Emilia praetermissa leaf extract on the haematological and biochemical parameters of stress induced ulcerated Wistar rats

December 2012

Effects of Emilia praetermissa leaf extract on the haematological and biochemical parameters of cold-water stress induced ulceration in albino rats were the focus of this study. Blood samples collected from stress induced ulcerated Wistar rats by cold water immersion were used to evaluate the haematological and biochemical parameters. This study was conducted using twenty rats randomly divided into four...

Author(s): A. O. Ebunlomo, A. O. Odetola, O. Bamidele, J. N. Egwurugwu, S. Maduka and J. Anopue

Assessment of the potency of some selected anti-malaria drugs on the supplements of vitamin B2 and orange fruit juice (combination therapy)

December 2012

Current practice in treating cases of malaria is based around the concept of combination therapy, since this offers several advantages - reduced risk of treatment failure, reduced risk of developing resistance, enhanced convenience and reduced side-effects. The effect of the supplements vitamin B2 (Riboflavin) and orange fruit juice on the potency and efficacy of some selected anti-malaria drugs (Armact, Coartem, Waipa...

Author(s): Adumanya O. C., Uwakwe A. A., Odeghe O. B., Essien E. B. and Okere T. O.

A Biflavonoid and a Carotenoid from Rhus leptodictya: Isolation, Characterization and Antibacterial Properties

November 2012

Acetone extracts of the leaves of Rhus Leptodictyawere studied for antibacterial activity usingbioautography and micro titre plate assay techniques against four nosocomial bacterial pathogens - Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, andEnterococcus faecalis. A bioassay guided fractionation showed that the activity was concentrated in the carbon tetrachloride fraction. A...

Author(s): Songca SP, Sebothoma C, Samuel BB and Eloff JN

Antioxidant screening of ethanolic and aqueous extracts of Organum vulgare L. in-vitro

November 2012

The present study was envisaged to assess the rationality for the use of traditionally invogue herb Organum vulgare as an anti-oxidant agent. Potential antioxidative activity of O. vulgare was evaluated using various in vitro methods including post mitochondrial supernatant (PMS) and microsomal lipid peroxidation, DNA sugar damage, 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical...

Author(s): Rubina Majid, Latief Ahmad and M. A. Zargar

Measurement of cholesterol sub-fractions, high density lipoprotein 2 and high density lipoprotein 3, in HIV infected patients treated with highly active antiretroviral therapy in Burkina Faso

October 2012

This paper described dyslipidemia caused by the metabolic effects of HIV and exposure to antiretroviral therapy. The aim of this study was to appreciate the interest of the measurement of HDL sub-fractions in the monitoring of human immunodeficiency virus (HIV) infected patients on antiretroviral treatment. A case-control study was carried out on 31 HIV infected before (naive) highly active antiviral therapy (HAART...

Author(s): Jean Sakandé, Josiane B Kaboré, Elie Kabré, Boblwendé Sakandé and Mamadou Sawadogo

Effects of methanol extract of Vernonia amygdalina leaf on survival and some biochemical parameters in acute Trypanosoma brucei brucei infection

October 2012

The effects of methanol extract of Vernonia amygdalina leaf (chosen from several extracts tested) on survival, parasitaemia, packed cell volume and some biochemical parameters were investigated in acute Trypanosoma brucei brucei infection. Results showed that the extract was relatively safe with median lethal dose, LD50 ≥5000 mg/kg/day. Although none of the extracts tested cured infected...

Author(s): Yusuf, Aminu Bashir, Umar, Ismail Alhaji and Nok, Andrew Jonathan

Heavy metals distribution and lipid profile in the stomach of cow grazed in Akungba-Akoko, Ondo State, Nigeria

June 2012

Essential oils were obtained by hydro distillation of dried leaves from two kinds of Plectranthus tenuicaulis (Hook f.) J. k. Morton grown in Gabon and were analyzed using GC-FID, GC-MS, 1H and 13C NMR. The main constituent was (R), (E)-6,7-epoxyocimene [(E)-myroxide] (72.2 to 83.8%) with small amounts of (Z)-6,7-epoxyocimene (0.6 to 1.3%), (E) and (Z)-β-ocimene (1.1 to...

Author(s): Bikanga Raphaël, Obame-Engonga Louis-Clément, Agnaniet Huguette, Makani Thomas, Anguile Jean Jacques, Lebibi Jacques, and Menut Chantal

Heavy metals distribution and lipid profile in the stomach of cow grazed in Akungba-Akoko, Ondo State, Nigeria

June 2012

The distribution of heavy metals: manganese, chromium, cadmium, copper, arsenate, iron and lead together with lipid profiles were investigated in the stomach of cow grazed in Akungba-Akoko region of Ondo State, Nigeria. This sample was analyzed using Atomic Absorption Spectrophotometric method (AAS) with wet digestion method. The results showed that the heavy metals concentrations in the stomach of the cows are: Mn...

Author(s): Elekofehinti O. O., Omotuyi I. O., Olaremu A. G. and Abayomi T. G.

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