African Journal of
Biochemistry Research

  • Abbreviation: Afr. J. Biochem. Res.
  • Language: English
  • ISSN: 1996-0778
  • DOI: 10.5897/AJBR
  • Start Year: 2007
  • Published Articles: 384

AJBR Articles

January 2011

Comparative effects of the leaves of Vernonia amygdalina and Telfairia occidentalis incorporated diets on the lipid profile of rats

The study compared the effects of the leaves of Vernonia amygdalina (VA) and Telfairia occidentalis(TO) incorporated diet on the lipid profiles of rats. The rats were fed for 28 days on diets specially formulated to contain 5, 15 and 30% by weight respectively of the leaves of each plant while the control group was fed standard rat diet. The serum total cholesterol (TC), triacylglycerol (TG), high-density...

Author(s): C. E. Ugwu, J. E. Olajide, E. O. Alumana and L. U. S. Ezeanyika

  • Article Number: A99BAE412117

January 2011

Antioxidative activity and catechin content of four kinds of Uncaria gambir extracts from West Sumatra, Indonesia

Gambir cubadak (GC), gambir udang (GU), gambir riau mancik (GRm) and gambir riau gadang (GRg) are popular cultivars of Uncaria gambir in Siguntur, West Sumatra, Indonesia. The aqueous extract of gambir has been used as traditional medicine to treat diarrhea, sore throat and some studies have attributed it to the presence of antioxidant properties. The purpose of this study was to characterize the...

Author(s): Tuty Anggraini,, Akihiro Tai, Tomoyuki Yoshino and Tomio Itani

  • Article Number: 11A9BF212127

January 2011

Enrichment methods for revealing lower molecular weight biomarkers in human breast plasma proteome

Breast cancer is the most common malignancy in women, comprising about 18% of all female cancers. The most important tools in screening and early detection are imaging techniques: mammography, ultrasonography and magnetic resonance imaging. However, up to 20% of new breast cancer incidents cannot be detected by these methods. Up to now, poor diagnosis of breast cancer is due to a lack of specific biomarkers....

Author(s): Bechr Hamrita, Hela ben Nasr#, Sami Remadi, Anouar Chaïeb and Karim Chahed,   #Bechr Hamrita and Hela ben Nasr contributed equally to this study and are co-first authors.

December 2010

Correlation between moderate Plasmodium falciparum malarial parasitaemia and antioxidant vitamins in serum of infected children in South Eastern Nigeria

The levels of antioxidant vitamins were estimated in Plasmodium falciparum malarial infected children aged 0 to 12 years. 113 children with P. falciparum infection were selected based on laboratory evidence and clinical symptoms. 87 apparently healthy children with no malarial parasitaemia were included as the control subjects. P. falciparum parasitaemia and serum levels of antioxidant...

Author(s): I. Onyesom, R. C. Ekeanyanwu and N. Achuka

  • Article Number: 988892511708

December 2010

The use of cholinergic biomarker, cholinesterase activity of blue mussel Mytilus edulis to detect the effects of organophosphorous pesticides

The aim of the study was to investigate the effects of organophosphorous pesticide on thecholinesterase activity of different organs of Mytilus edulis. The mussels were exposed to serial dilutions of the pesticides (0, 50, 100, 200, 500, and 1000 µg/l) for 96 h. A significant inhibition of the cholinesterase activity from gill occurred at the lowest concentration, which indicated that gill was the...

Author(s): K. Yaqin and P. D. Hansen

  • Article Number: F8090D911719

December 2010

Biochemical profile of sodium selenite on chemically induced hepatocarcinogenesis in male Sprague-Dawley rats

Despite the success of experimental, clinical and epidemiological studies on selenium as an anti-cancer agent, basic studies on the effects of selenium are still scanty. This study was designed to investigate the biochemical effects of sodium selenite using preventive and therapeutic approaches on chemically induced hepatocarcinogenesis in rats. Rats were divided randomly into 6 groups: negative control, positive...

Author(s): Nasar Yousuf Alwahaibi, Siti Belkis Budin and Jamaludin Mohamed

  • Article Number: EC7479611732

November 2010

Betaine reduces hyperhomocysteinemia and enhances 5-hydroxyindoleacetic acid in ethanol-induced hyperhomocysteinemia in rabbits

Hyperhomocysteinemia is a hypothesis for the association of homocysteine with cerebrovascular diseases, neurodegenerative diseases and depression of mood. Thus, we examined whether oral betaine can act as a preventive agent in ethanol-induced hyperhomocysteinemia on the monoaminergic system. A total of 32 New Zealand White rabbits were divided into four groups (n=8); the Control group (C). The Ethanol group (E) was...

Author(s): Masoud Alirezaei, Mehdi Saeb, Katayoun Javidnia, Saeed Nazifi, Najmeh Khalighyan, and Saeedeh Saeb

  • Article Number: 848A2C811684

November 2010

Biochemical markers in semen and their correlation with fertility hormones and semen quality among Sudanese infertile patients

Several biochemicals in semen are secreted by the accessory glands in the reproductive tract. This biochemical can be used as diagnostic predictors for the disorders in the male reproductive system. To assess the level of biochemical markers in semen, their relation to fertility hormones and spermogram among Sudanese infertile patients were studied. The biochemical markers studied were fructose, citric acid, zinc...

Author(s): Abdelmula M. Abdella, Al-Fadhil E. Omer and Badruldeen H. Al-Aabed

  • Article Number: FBE915211692

October 2010

Effects of vitamin E and folic acid on some antioxidant enzymes activities of female Wistar rats administered combined oral contraceptives

In this study, the effects of vitamin E and folic acid on the superoxide dismutase (SOD), catalase (CAT), malondialdehyde (MDA) production and glutathione-S-transferase (GST) activities in female wistar rats treated with combined oral contraceptives (COC) containing ethinyl estradiol in combination with levonorgestrel were determined. Twenty female rats were divided into four groups: group A (control) received distilled...

Author(s): Akinsanya, Mushafau  A., Adeniyi, Taiwo T., Ajayi, Gabriel O and Oyedele, Musbau A.

  • Article Number: 3634C6D11620

October 2010

The prevalence of malaria infection in pregnant women living in a suburb of Lagos, Nigeria

Malaria during pregnancy continues to be a major health problem in endemic countries with clinical consequences including death of both mother and child. In Nigeria, statistics shows that as many as 300,000 lives especially those of children and pregnant women are lost annually to malaria. This study was aimed at assessing the prevalence of malaria among pregnant women living in Ojo local council, a suburb of Lagos...

Author(s): Raimi, O. G., and Kanu, C. P. 

  • Article Number: A5452CB11650

September 2010

Alpha-amylase inhibitor of amadumbe (Colocasia esculenta): Isolation, purification and selectivity toward α- amylases from various sources

Two proteins (A-1 and B-2) with a-amylase inhibitor activity  were extracted and partially purified from Colocasia esculenta tubers through 80% ammonium sulphate fractionation, ion-exchange chromatography on DEAE-Sephacel and gel-chromatography on Sephadex G-100. The molecular weight of A-1 and B-2 were estimated to be about 17000 and 19000 daltons, respectively. The inhibitors inactivated a-amylases of...

Author(s): R. McEwan, R. P. Madivha, T. Djarova, O. A. Oyedeji and A. R. Opoku

  • Article Number: DC1740A11541

September 2010

Influence of sub-chronic oral exposure to high monosodium glutamate on some serum markers of the renal functions in male Wistar rats

Monosodium glutamate (MSG) is a flavor enhancing food additive that may be present in packaged food without appearing on the label. This could increase the possibility of its inadvertent consumption in high concentration. The study investigated the effects of MSG on some serum markers of renal functions in adult male Wistar rats by daily oral exposure to 3 ml kg-1 dose distilled water (DW) and 15 mg kg-1 MSG...

Author(s): Egbuonu Anthony C. Cemaluk, Ejikeme P. Madus and Obasi L. Nnamdi

  • Article Number: F46700911543

September 2010

Adsorption, metabolism and degradation of erythromycin in giant freshwater prawn and tilapia aquaculture in Mekong River Delta

Adsorption, metabolism and degradation of erythromycin in freshwater prawn and tilapia aquaculture in Mekong River Delta were monitored and evaluated. They were fed practical diets medicated with erythromycin (50 and 100 mg. kg-1 body weight for 7 days). Erythromycin residues in their muscle were determined by the liquid chromatography - mass spectrometry/ mass spectrometry (LC-MS/MS) method. Our study provided...

Author(s): N. P. Minh, T. B. Lam and T. T. D. Trang

  • Article Number: 36BFBCD11581

August 2010

In vitro and in vivo evaluation of free radical scavenging potential of ethanolic extract of Podophyllum hexandrum

The study was aimed at evaluating the antioxidant activity of ethanolic extract of rhizome of Podophyllum hexandrum under in vitro and in vivo situations. The extract was found to contain a large amount of polyphenols and also exhibit an immense reducing ability. At a concentration of 250 µg/ml, 48% of H2O2 radicals could be scavenged by the extract. The extract also inhibited...

Author(s): Showkat Ahmad Ganie, Mohmmad Afzal Zargar, Akbar Masood and Ehtishamul Haq

  • Article Number: A77978711527

August 2010

Expression of chitosanase gene from Aspergillus fumigatus JXSD-97 in Pichia pastoris

In this study, the plasmid pPIC9K-CSN was transformed into Pichia pastorisstrain GS115 by electroporation and the high expression transformants with G418 resistance were obtained. The expression conditions for CSN in P. pastoris, such as the expression time, pH value and methanol concentration in the BMMY were optimized. The maximum activity of CSN is about 100 mg/L under optimized condition (96 h of 0.5%...

Author(s): Yang Li, Yang Ping and Wang Manying

  • Article Number: 83B18F811532

August 2010

Corncob is the optimum carbon resource for the growth of Tremella aurantialba

The minimum medium without carbon source was used to investigate the effects of five kinds of hexoses, four kinds of pentose, four kinds of bi-saccharide and three kinds of polysaccharides on Tremella aurantialba growth. The result demonstrated that (1) The fittest carbon source of T. aurantialba was the five-carbon aldose in all the tested monosaccharides; (2) Polysaccharides linked with...

Author(s): Zhi-Cai Zhang, Mingxia Chen, Xin Li and Wangli Shen

  • Article Number: 8690E2B11535

August 2010

Metabolic engineering of an ethanol-tolerant Escherichia coli MG1655 for enhanced ethanol production from xylose and glucose

Efficient ethanol production will require a recombinant to able to ferment a variety of sugars (pentoses, and hexoses), less formation of by-products, as well as to tolerate high ethanol stress. In this study, a mutant (MGE) that can grow in 60 g ethanol/l was selected from Escherichia coli MG1655 by enrichment method with increasing concentrations of ethanol. The ethanol-tolerant mutant was used as the host...

Author(s): Ruiqiang Ma, Ying Zhang, Haozhou Hong, Wei Lu, Wei Zhang Min Lin and Ming Chen

  • Article Number: ECF1BFD11537

July 2010

Evaluation of nutritional and antinutritional characteristics of Obeche (Triplochition scleroxylon scleroxylon) and several Mulberry (Morus alba) leaves

The biochemical composition of some selected varieties of White Mulberry and Obeche leaves were investigated to ascertain their nutritional and antinutritional values. Three varieties of White Mulberry leaves (S36, S54 and K2) were harvested from Ondo State sericulture centre while Obeche leaves were harvested from Aponmu Forest Reserve located in Ondo State, Southwestern Nigeria, for analysis. Proximate chemical...

Author(s): S. A. Adeduntan and A. S. Oyerinde

  • Article Number: CB3010911484

July 2010

Phytochemical screening and histopathological effects of single acute dose administration of Artemisia annua L. on testes and ovaries of Wistar rats

Artemisia annua L. is a medicinal plant whose derivatives are used in the treatment of malaria. Phytochemical screening and histopathological effects of single acute intraperitoneal dose of the alcoholic extract of A. annua, were investigated in Wistar rats in this study. Thirty five adult albino Wistar rats (109 - 307 g) of both sexes used for the study were randomly assigned on the basis of weight and...

Author(s): P. O. Ajah and M. U. Eteng

  • Article Number: F1CD96411505

July 2010

Standardized alcoholic extract of Phyllanthus fraternus exerts potential action against disturbed biochemical parameters in diabetic animals

Alcoholic extract of Phyllanthus fraternus Webster whole plant (PFAE) prepared by successive solvent treatment was administered at a dose of 500 mg/kg body weight once in a day for 21 days to the alloxan induced diabetic albino rats. Certain biochemical parameters that is lipid profile (total cholesterol, high density lipoprotein, triacylglycerols), kidney functions (urea, creatinine) and liver functions...

Author(s): Munish Garg, Chanchal Garg, V. J. Dhar and A. N. Kalia

  • Article Number: 4402F3611513

July 2010

Screening of antioxidant activity, total phenolics and GC-MS study of Vitex negundo

The present study was carried out for identification of the phytochemicals present in the Vitex negundo leaves and also evaluate the total phenols, total flavonoids and antioxidant activity of the leaf extract. Total phenols was carried out by Folin Ciocalteu method and the phenolic content was 27.72 mg/100 of gallic acid equivalent (GE). Antioxidant activity was evaluated by DPPH method and the leaves...

Author(s): P. Praveen Kumar, S. Kumaravel and C. Lalitha

  • Article Number: 743A94611519

June 2010

Effects of diet-induced hypercholesterolemia on the lipid profile and some enzyme activities in female Wistar rats

The effects of a high dietary soybean oil and cholesterol on serum total cholesterol, low density lipoprotein (LDL-C), high density lipoprotein (HDL-C), and triglycerides were investigated. Total protein, albumin, glucose, gamma glutamyl transferase (GGT), aspartate aminotransferase (AST) and alanine amino transferase (ALT) activities were also investigated in weanling female Wistar rats for eight weeks. Two groups of...

Author(s): Gloria A. Otunola, Oyelola B. Oloyede, Adenike T. Oladiji and Anthony A. Afolayan

  • Article Number: 5D7026911395

June 2010

Malate dehydrogenase from blood stream Trypanosoma vivax exists in isoenzyme forms

Malate dehydrogenase was isolated and partially purified from blood streamTrypanosoma vivax. The enzyme exists in isoenzyme forms (MDH1 and MDH2). The relative molecular weights of MDH1 and MDH2 determined by Sodium dodecyl sulphate polyacrylamide gel electrophoresis were 61 and 63 kdal. respectively. MDH2 lost activity immediately after purification. It has purification fold of 15 and percentage...

Author(s): A. U. Wurochekke, A. J. Nok, H. M. Inuwa and C. E. Gimba

  • Article Number: 2EAA93511418

June 2010

Purification and characterization of the α-amylase isolated from Penicillium camemberti PL21

The amylase family of enzymes is a great significance due to its wide area of potential application. α-amylase from Penicillium camemberti PL21 obtained from I. N. A. (The technological laboratory of Agriculture National Institute Paris- France) and using orange waste as substrates was produced under optimum conditions, after 168 h of incubation and subjected for purification and characterization. The...

Author(s): Tahar Nouadri, Zahia Meraihi, Djekrif-Dakhmouche Shahrazed and Bennamoun Leila

  • Article Number: 3B4802A11438

June 2010

The distribution of cyanide detoxifying enzymes (rhodanese and 3- mercaptopyruvate sulphurtransferase) in different species of the family Cichlidae (Tilapia zillii, Sarotherodon galilaeus and Oreochromis niloticus)

The cyanide metabolising enzymes (rhodanese and mercaptopyruvate sulphurtransferase) were estimated in different tissues of three species of tilapia (Tilapia zilli, Sarotherodon galileus,and Oreochromis niloticus) from two locations (Aiba and Osinmo reservoirs, both in the South-Western region of Nigeria). The enzyme activities were carried out by measuring the amount of thiocyanate produced by the two enzymes...

Author(s): Okonji Raphael Emuebie, Popoola Michael Olaoluwa, Kuku Adenike and Aladesanmi Omolara Titilayo

  • Article Number: B5C8B6211451

June 2010

Characterization of antioxidant and antimicrobial compounds of cinnamon and ginger essential oils

Essential oils obtained from the bark of Cinnamomum zeylanicum (cinnamon) and the rhizomes of Zingiber officinale (ginger) were characterized by analytical TLC and GC/MS, and their antimicrobial and antioxidant compounds were detected by TLC-bio-autography assays. Essential oil of cinnamon bark (CEO) was found to be a unique aromatic monoterpene-rich natural source, with trans-cinnamaldehyde...

Author(s): G. S. El-Baroty, H. H Abd El-Baky, R. S. Farag and M. A. Saleh

  • Article Number: 8D4DEA111465

May 2010

Production of yeast using acid-hydrolyzed cassava and poultry manure extract

Cassava is made up of starch as its major nutritive reserve. Starch which is one of the most important products synthesized by plants is consumed as food and can be used in industrial processes. This investigation seeks to explore the availability of cassava as a source of glucose as well as poultry manure as a source of nitrogen in the production of yeast. Cassava flour was hydrolyzed with 0.5% (v/v) concentrated...

Author(s): L. I. Osumah and N. J. Tonukari

  • Article Number: AFEA22E11312

May 2010

AQY1 gene from Debaryomyces hansenii

Aquaporins are members of the major intrinsic protein superfamily of integral membrane proteins that enable the transport of water, glycerol and other solutes across membranes in diverse organisms. In yeasts, the proposed physiological roles of aquaporins are related to their contribution to freeze tolerance, osmoregulation and water transport. This article reports a contribution to the freeze tolerance in the...

Author(s): Juan Carlos González-Hernández

  • Article Number: 56A587A11332

May 2010

Ginger extract (Zingiber officinale) triggers apoptosis and G0/G1 cells arrest in HCT 116 and HT 29 colon cancer cell lines

Although many studies have shown the antitumor properties of ginger extract (Zingiber officinale), little is known regarding the mechanism of its effects. This study was conducted to determine the mechanism of antitumor effects of ginger extract by evaluating apoptosis rate and cell cycle progression status in colon cancer cell lines HCT 116 and p53 defective HT 29. HCT 116 and HT 29 cells were cultured in the presence...

Author(s): Shailah Abdullah, Siti Amalina Zainal Abidin, Noor Azian Murad, Suzana Makpol, Wan Zurinah Wan Ngah and Yasmin Anum Mohd Yusof

  • Article Number: A5B217C11349

April 2010

Application of acid-hydrolyzed cassava (Manihot esculenta) and cowpea (Vigna unguiculata) for the production of yeast (Saccharomyces cerevisiae)

Much progress has been made in the cultivation and production of cassava (Manihot esculenta) and cowpea (Vigna unguiculata) in Nigeria. In the present study, investigation was carried out on the possibility of using cassava flour as a source of glucose as well as cowpea as source of nitrogen in the production of yeast. Acid hydrolysis (using dilute H2SO4) of cassava and cowpea was undertaken to release the sugars and...

Author(s): Nyerhovwo J. Tonukari and Linda I. Osumah

  • Article Number: E6992CB11198

April 2010

Captopril interferes with some serum biochemical findings

Captopril is a widely used anti-hypertensive drug that acts by inhibiting angiotensin-converting enzyme. This work has been carried out to investigate the effects of captopril on some common biochemical laboratory parametres in the sera of patients receiving the drug. For this study, 40 subjects were included, all within the age range of 40 to 63 years and with newly diagnosed essential hypertension. From each patient,...

Author(s): I. A. Ibrahim, F. S. Al-Joudi , R.  Waleed Sulaiman  and B. Hilal AL-Saffar

  • Article Number: EC757BD11233

April 2010

Effect of ferric oxide nanoparticles on microtubules organization

Nanoparticles (NPs) are widely used in several manufactured products. The small size of nanoparticles facilitates­ their uptake into cells as well as transcytosis across epithelial cells into blood and lymph circulation to reach different sites, such as the central nervous system. Studies have shown different risks of Fe2O3NPs in the neuronal system and other organs. They are membrane-bound layer aggregates or...

Author(s): Ali Khaleghian, Gholam Hossein Riazi, Shahin Ahmadian, Mahmoud Ghafari, Marzieh Rezaie, Akira Takahashi, Yutaka Nakaya and Hossein Nazari

  • Article Number: 1555A4311254

April 2010

Synergistic effects of glucan and resveratrol

Recent data showing that glucan stimulates defense reactions in plants through synthesis of resveratrol, led us to study the possible synergetic effects of a glucan-resveratrol complex on immune reactions in mice. We measured phagocytic activity, expression of CD4 marker on spleen cells, IL-2 secretion and antibody response. In all cases we confirmed the stimulatory effects of glucan. Resveratrol alone had either limit...

Author(s): Vaclav Vetvicka and Zuzana Vancikova

  • Article Number: D4B8D1E11261

April 2010

Assessing the role of RecA protein in the radioresistant bacterium, Deinococcus geothermalis

The moderately thermophilic bacterium Deinococcus geothermalis exhibits extraordinary resistance to ionizing radiation. RecA protein is considered to be one of the most important participants in radioresistance. To assess the role of the RecA protein in D. geothermalis, the recA gene was isolated from D. geothermalisand over expressed in Escherichia coli. After the D. geothermalis RecA...

Author(s): Haïtham Sghaier, Katsuya Satoh, , Hirofumi Ohba,  and Issay Narumi,

  • Article Number: 4122D0C11282

March 2010

Fermentation in cassava (Manihot esculenta Crantz) pulp juice improves nutritive value of cassava peel

A major challenge in using cassava peel as feed for animals is the presence of cyanogenic glycosides and the low concentration of protein. The present study investigated the possibility of upgrading cassava peels using fermented cassava pulp juice. Cassava pulp juice was squeezed out of grated cassava pulp and fermented for 3 days at ambient temperature. The microorganisms in the fermented pulp juice were identified...

Author(s): Naa Ayikailey Adamafio, Maxwell Sakyiamah and Josephyne Tettey

  • Article Number: 8AB81A811059

March 2010

Production of cuticle - degrading proteases by Beauveria bassiana and their induction in different media

The concern for the development of hyphomycete fungi as suitable biocontrol agents of insect pests leads to the isolation of various insect pathogenic fungi. Amongst them, one of the most studied entomopathogenic fungus is Beauveria bassiana. The conidia of mitosporic fungi adhere to the host cuticle and germinate to produce an infectious propagule, and produce a sequential release of extra cellular enzymes to...

Author(s): Priyanka Dhar and Gurvinder Kaur

  • Article Number: 3E2873A11120

March 2010

Optimization of culture parameters to enhance production of amylase and protease from Aspergillus awamori in a single fermentation

Concomitant production of amylase and protease by Aspergillus awamorinakazawa MTCC 6652 was enhanced in a single fermentation by media engineering and optimization of other important parameters. Wheat bran was considered as a suitable substrate for production of amylase and protease by A. awamori in a single fermentation as none of the additional substrate such as powder of peanut, corn, soybean seeds and...

Author(s): Sangeeta Negi and Rintu Banerjee

  • Article Number: E2314C711148

March 2010

Hepatoprotective role of Garcinia kolanut (Heckel) extract on methamphetamine: Induced neurotoxicity in mice

The hepatoprotective effect of aqueous extract of Garcinia kola (AEGK) was studied in 60 mice of mixed sexes. The animals were divided into 6 groups of 10 mice each. Group I received normal saline, Groups II and III got 100 and 200 mg/kg AEGK (orally), respectively. Group IV received 10 mg/kg methamphetamine (MAM) (s.c.) only. Groups V and VI got 100 and 200 mg/kg of AEGK respectively, before 10 mg/kg methamphetamine...

Author(s): Gabriel Oze, Iheanyi Okoro, Austin Obi and Polycarp Nwoha

  • Article Number: 8BCCC2211162

February 2010

Lecithin: Cholesterol acyltransferase, lipoprotein lipase and lipoproteins in adult Nigerians with sickle cell disease

Lecithin: Cholesterol acyltransferase (LCAT) is a glycoprotein enzyme involves in the esterification of plasma cholesterol to form cholesteryl ester and is important in the maturation of high density lipoprotein. Lipid metabolism in sickle cell anaemia patients may be affected. The objective of this study was to determine the activities of serum lecithin: cholesterol acyltransferase, lipoprotein lipase, lipids and...

Author(s): M. A. Emokpae, , P. O. Uadia and H. B. Osadolor

  • Article Number: 8F62AF710949

February 2010

Toxic effect of lead on kidney function in rat wistar

Lead is one of the environmental pollutants that can threat the life of living creatures in many ways. This study was carried out to investigate the effect of lead exposure on kidney function. Fourteen male Wistar rats were divided into 2 groups; group 1 was given a tap water diet and group 2 was given 1000 ppm lead acetate in drinking water for 8 weeks. Lead concentration in blood was determined by atomic absorption....

Author(s): Missoun F, Slimani M and Aoues A

  • Article Number: 547955B10974

February 2010

Changes in haemorrheologic and fibrinolytic activities upon hypertension and diabetic chemotherapy in Calabar diabetic residents, Nigeria

This research was carried out to assess the effect of hypertension on haemorrheologic and fibrinolytic activities in fifty (50) diabetics resident in Calabar municipality and the values obtained were compared with those of fifty (50) age and sex-matched non diabetics in the same locality. Relative plasma viscosity plasma fibrinogen concentration, euglobulin lysis time and fasting blood sugar were determined using...

Author(s): M. S. Edem, A. O. Emeribe and J. O. Akpotuzor

  • Article Number: 3D56F8910989

February 2010

The response to iron deficiency of two sensitive grapevine cultivars grafted on a tolerant rootstock

Two sensitive cultivars were examined, Vittoria and Italia, grafted on a tolerant rootstock (140 Ruggeri). Two levels of iron chlorosis in scions were selected, initial and evident, and compared to the healthy rootstock (control). The fractions of extracellular and cytoplasmatic cations, chloroplastic mobile, loosely linked, strongly linked and residual cations as well as the active fraction were...

Author(s): M. A. Russo, F. Sambuco and A. Belligno

  • Article Number: 2A6DF6E11002

February 2010

The effects of aqueous extracts of the leaves of Hibiscus rosa-sinensis Linn on renal function in hypertensive rats

The leaves of Hibiscus rosa-sinensis Linn (Family Malvaceae) have been used in ethnomedicine for the treatment of various human diseases such as aphrodisiac, hypertension, wound healing, diabetes mellitus and cancer. In this present study, the effect of 200 mg/kg of the aqueous leaf extract on the renal function of hypertensive rats was investigated. The administration of H. rosa-sinensis leaves...

Author(s): Imafidon E. Kate and Okunrobo O. Lucky

  • Article Number: 3CD2F8211018

February 2010

Effects of soaking and boiling and autoclaving on nutritional quality of Mucuna flagellipes (Ukpo)

The effect of soaking and boiling, and autoclaving on nutritional factors (proximate and mineral) and anti-nutritional qualities of legume, Mucuna flagellipes were studied. Batches of seeds were soaked for 6, 12, 18 and 24 h in distilled water at room temperature, then boiled in water for 30, 45, 60 or 90 min respectively. Another batch of the M. flagellipes was autoclaved for different duration of...

Author(s): E. A. Udensi, N. U. Arisa and E. Ikpa

  • Article Number: 6CD16C811036

February 2010

The influence of 950 MHz magnetic field (mobile phone radiation) on sex organ and adrenal functions of male rabbits

Mobile phones are used frequently and held close to the body thus they are potentially dangerous sources of electromagnetic (EM) radiations. The clear effects of EMF (electromagnetic field) on many organs of the body have not been known until now and have puzzled scientists. The objective of this study was the evaluation of the influence of different powers (3 and 6 W) of 950 MHz magnetic field on testosterone, FSH...

Author(s): M. R. Sarookhani, M. Asiabanha Rezaei, A. Safari, V. Zaroushani and M. Ziaeiha

  • Article Number: 898A44712184

January 2010

Effect of egusi melon oil on lecithin: Cholesterol acyltransferase activity in rats fed a cholesterol diet

The effect of feeding egusi melon oil as a supplement to a cholesterol-based diet on serum lecithin: cholesterol acyltransferase activity of rats was evaluated. The rats were divided into two groups designated: control and test respectively. Rats in the test group were fed 5% cholesterol diet supplemented with 5% egusi melon oil while the control rats received 5% cholesterol diet...

Author(s): G. C. Ojieh, G. O. Eidangbe and O. M. Oluba

  • Article Number: C1A9DB910854

January 2010

Assessment of current iodine status of pregnant women in a suburban area of Imo State Nigeria, twelve years after universal salt iodization

Three hundred and two pregnant women participated in this study. Our results showed that the range, mean and median urinary iodine excretion (UIE) were 28.1 to 218.1, 152.09 ± 41.65 and 163.1 µg/l, respectively. The range, mean and median TSH concentration were 0.7 - 5.9, 1.4 ± 0.7 and 1.3 µIU/ml, respectively. Our results showed that none of the women have severe iodine deficiency, 2% had...

Author(s): Cosmas O. Ujowundu, Agwu I. Ukoha, Comfort N. Agha, Ngwu Nwachukwu and Kalu O. Igwe

  • Article Number: 863C90A10886

January 2010

A study on prostate specific antigen (PSA) with the ratio of free to total PSA

Prostate Specific Antigen (PSA) is a glycoprotein produced as a marker by prostate gland for prostate cancer, benign prostate hyperplasia and prostatitis. Study objective is to evaluate f/t PSA ratio to distinguish the Benign Prostate Hyperplasia (BPH) and prostate cancer patients in and around SRM University. To define the age specific reference ranges of PSA in control and test group at Chennai, India. Healthy men...

Author(s): Chavan Atish, Suman Diggi Prasad, Rawal Mukesh, Kandasamy Surendran, Sivapatham Sundaresan, Thangarajan Thangapannerselvem

  • Article Number: 5E4EF1210899

January 2010

Cytoplasmic, peroxisomal and mitochondrial membrane phospholipid alteration in 31-diamino-azo-benzene (31-DAB)-induced hepatocellular carcinoma

Alteration in the cytoplasmic, mitochondrial and peroxisomal membrane phospholipid has been investigated in 31- diamino-azo-benzene (DAB) -induced hepatocellular carcinoma in rats. The cytoplasmic membrane of tumour group shows 27.5, 19.7, 38.7 and 34.7% increase in phosphatidylserine, phosphatidylcholine, phosphatidylethanolamine, and sphingomyelin respectively compared with the control group, mitochondrial membrane...

Author(s): Omotuyi I. O., Ologundudu A., Okugbo T. O., Oluyemi K. A. and Omitade, O. E.

  • Article Number: 7FEE83012077

January 2010

Investigation of antimicrobial and plasma coagulation property of some molluscan ink extracts: Gastropods and cephalopods

The ink secretion of molluscan species was identified as one of the novel sources of bioactive compounds. Aqueous ink extracts of Dollabella auricularia inhibited the growth of Gram-positive and Gram-negative bacteria. In addition to D. auricularia, Octopus vulgaris and Sepia aculeate ink samples showed antifungal activity. The antimicrobial activities of the samples were not due to the...

Author(s): R. Vennila, R. K. Rajesh kumar, S. Kanchana, M. Arumugam and T. Balasubramanian

  • Article Number: 9E95B4E12094

Page 5 of 8, showing 50 records out of 384 total, starting on record 201, ending on 250