Journal of
Pharmacognosy and Phytotherapy

  • Abbreviation: J. Pharmacognosy Phytother.
  • Language: English
  • ISSN: 2141-2502
  • DOI: 10.5897/JPP
  • Start Year: 2009
  • Published Articles: 222

JPP Articles

Phytochemical analysis, antioxidant and antimicrobial activities of leaves and flowers ethyl acetate and n-butanol fractions from an Algerian endemic plant Calycotome spinosa (L.) Link

December 2017

Calycotome spinosa (L.) Link is one of the important plants in traditional medicine especially in Algeria. The present work deals with the phytochemical screening, the flavonoids extraction from leaves and flowers of this plant, the quantification of total polyphenols and flavonoids, as well as the evaluation of antioxidant and antimicrobial properties of ethyl acetate and n-butanol fractions. While, the rest,...

Author(s): Radia Cherfia, Mounira Kara Ali, Imen Talhi, Akila Benaissa and Noreddine Kacem Chaouche

Phytochemical and biological analyses of Citharexylum spinosum

December 2017

The phytochemical screening of Citharexylum spinosum L. aerial parts resulted in the presence of flavonoids, tannins, carbohydrates and/or glycosides, triterpenes and/or sterols and saponins. The percentage of hydrocarbons and sterols in C. spinosum petroleum ether extract were 99.57 and 0.3%, respectively. In petroleum ether extract, saturated fatty acids (78.76%) and unsaturated fatty acids (9.14%) were found....

Author(s): Amel M. Kamal, Mohamed I. S. Abdelhady#, Heba Tawfeek#, Maha G. Haggag# and Eman G. Haggag#

Evaluation of some biological activities of Trigonella hamosa aerial parts

November 2017

The antimicrobial activity of T. hamosa aerial parts extract against Bacillus subtilis, Staphylococcus aureus, Enterococcus fecalis, Escherichia coli, Pseudomonas auregenosa, Candida albicans, Fusarium sp. and Aspergilus niger was evaluated by disc diffusion method. The minimum inhibitory concentrations (MICs) for susceptible test microorganisms were further determined. Also the antioxidant and α-amylase...

Author(s): Sameer H. Qari and Nayer M. Fahmy

Ethnobotanical survey of plants used in the management of mental illnesses in some selected local government areas of Plateau State, Nigeria

October 2017

Mental illness refers to all diagnosable mental disorders which are characterised by abnormalities in thinking, feelings or behaviours. Ethnobotanical study surveyed the different types of medicinal plants used for the treatment of mental illness in Bassa, Pankshin, and Kanke Local Government Areas of Plateau State, Nigeria. Information was obtained from traditional medicine practitioners, herbalist and herb sellers,...

Author(s): Ior L. D., Otimenyin S. O., Okwori V. A., Umar D. M. and Azila J. J.

Pharmacognostic evaluation of the leaves and roots of Cassia sieberiana DC.

October 2017

Cassia sieberiana DC. (Leguminosae - Caesalpinioideae), commonly known as drumstick and ‘aridantooro’ in Yoruba, is a perennial tree native to Africa. It is used in ethno-medicine to manage arthritis and rheumatism. Pharmacological activities such as myorelaxant, antispasmodic, anti-inflammatory, and antimicrobial have been reported in literature. Pharmacognostic investigation including microscopy,...

Author(s): Fatokun Omolola T., Esievo Kevwe B., Ibrahim Jemilat A. and Kunle Oluyemisi F.

Antioxidant potential and cytotoxicity of Randia dumetorum Lam. leaf extract

September 2017

The aim of the current study was to explore the antioxidant potential and cytotoxicity of different ’fractions from the leaf extract of Randia dumetorum. Proximate analysis and phytochemical screening were done with standard protocol. The antioxidant activity was evaluated by using reducing power assay, total antioxidant capacity determination, determination of total phenolic content, determination of total...

Author(s): Abdullah-Al-Ragib, Md. Tanvir Hossain, Javed Hossain and Md. Jakaria,

Pharmacognostic studies and elemental analysis of Cassytha filiformis Linn

August 2017

Cassytha filiformis, a leafless and perennial vine with small scales as a replacement of the leaves is currently being used in the treatment of various disease conditions such as jaundice. Macroscopic/ organoleptic characters, microscopic, chemo-microscopic characters, numerical standards, and elemental analysis were determined from the whole plant of C. filiformis. Findings from this study revealed the presence of some...

Author(s): Adamu A. Ambi, Garba F. Nuru, Ahmed T. Mora and Abubakar Ahmad

Phytochemical and zootechnical studies of Physalis peruviana L. leaves exposured to streptozotocin-induced diabetic rats

August 2017

This is a phytochemical and zootechnical study on Physalis peruviana leaves in streptozotocin induced diabetic rats. This was part of a scientific development program of plant resources used in Congolese traditional medicine for the treatment of diabetes mellitus in which individual and community consequences are well established. Different fractions with hexane, ethyl acetate and the residue were obtained from the...

Author(s): C. N. Fokunang, F. K. Mushagalusa, E. Tembe-Fokunang, J. Ngoupayo, B. Ngameni, L. N. Njinkio, J. N. Kadima, F. A. Kechia, B. Atogho-Tiedeu, W. F. Mbacham and B. T. Ngadjui

Assessment of the effect of aqueous leaf extract of cassava (Mannihot esculenta) on adult Wistar rats

July 2017

This study aimed to explore the effect of aqueous leaf extract of Mannihot esculenta on the morphology and histology of the kidney of adult Wistar rats. Three groups of Wistar rats were used. Group A served as the control treated with 0.3 ml of normal saline, while groups B and C served as the experimental groups. Group B and C were treated with aqueous extract of M. esculenta orally at 0.2 and 0.5 ml, respectively for...

Author(s): Kebe E. Obeten, Imasa E. Ushie, Gabriel Udoaffah and Obi O. Ndifon

Potential health benefits and scientific review of ginger

July 2017

Ginger has been known for its several scientific properties and valued for the last 2500 years in different parts of the globe. Ginger has rich phytochemistry and several health promoting perspectives. In ginger family, Zingiber officinalis is one of most widely used species and it is found in several foods and beverages. Ginger has been used commonly to treat diarrhea, stomach upset, indigestion and nausea. It also has...

Author(s): Najim A. Jabir Al-Awwadi

Ethnopharmacological survey of plants used for the treatment of diabetes in the town of Sidi Slimane (Morocco)

June 2017

The study aimed to screen the antidiabetic plants used by 700 diabetic patients in the town of Sidi Slimane (northwestern Morocco). The results identified 59 species belonging to 28 botanical families, four of which are predominant (Lamiaceae: 9 species; Apiaceae: 7 species; Asteraceae: 5 species; Fabaceae: 4 species). The most used species are: Trigonella foenum-graecum, Oreganum vulgare, Salvia officinalis, Marrubium...

Author(s): M. Laadim, M. L. Ouahidi, L. Zidane, A. El Hessni, A. Ouichou and A. Mesfioui

In vivo anti-plasmodial activity and histopathological analysis of water and ethanol extracts of a polyherbal antimalarial recipe

June 2017

Anthocleista djalonensis A. Chev. (stem bark), Azadirachta indica A. Juss (stem bark and leaf), Cajanus cajan (L.) Huth. (leaf), Crescentia cujete L. (stem bark), Lawsonia inermis L. (leaf), Lophira alata Banks ex C.F. Gaertn. (stem bark), Myrianthus pruessii Engl. (leaf), Nauclea latifolia Sm. (stem bark), Olax subscorpioidea Oliv. (root), and Terminalia glaucescens Planch ex Benth. (stem bark and root) are combined...

Author(s): Mojirayo Rebecca Ibukunoluwa

Chemical constituents and biological activities of different solvent extracts of Prosopis farcta growing in Egypt

May 2017

Different solvent extracts from the aerial part of Prosopis farcta growing in Egypt have been biologically evaluated by studying their antimicrobial, anticancer and antioxidant activities. Furthermore, the chemical analysis using GC/MS has been performed for the promising extracts n-hexane and methylene chloride, and this analysis led to the identification of twenty six and thirty two compounds respectively from...

Author(s): Amal Mohamed Saad, Mosad Ahmed Ghareeb, Mohamed Sayed Abdel-Aziz, Hassan Mohamed Fawzy Madkour, Omar Maajal Khalaf, Ahmed Kamel El-Ziaty and Mamdouh Abdel-Mogib

Phytochemical and biological investigation of Eugenia uniflora L. cultivated in Egypt

May 2017

Eugenia uniflora L. (Myrtaceae) is a plant species used in folk medicine for treatment of various disorders. This study aims to quantify the phenolic and flavonoid contents of E. uniflora aqueous methanolic extract (AME), identification of its major constituents, as well as the evaluation of its biological activity. Quantification was performed using colorimetric assays. Column chromatographic separation was used for...

Author(s): Riham O. Bakr, Shaza A. Mohamed and Nermien E. Waly

Anti-asthma potential of dried Draco Spilopterus Wieg. 1834 (Philippine Flying Dragon) using mesenteric mast cell count by atopic allergy method

April 2017

Decocted Draco spilopterus has been utilized in the Philippines for the treatment of asthma associated with its strong folkloric beliefs however no scientific evidence was available to prove such claims. Thus, the researchers ventured into this study to determine the anti - asthma potential of dried D. spilopterus on male albino rats using mesenteric mast cell count by atopic allergy method. Fifteen D. spilopterus were...

Author(s): Gerard Lee L. See, Aj Et War Yazsine A. Ocampos, Nicole Angelli Y. Yap and Florencio V. Arce, Jr.

Mystroxylon aethiopicum chloroform root bark extracts phytochemical analysis using gas chromatography mass spectrometry

April 2017

Mystroxylon aethiopicum has been used by many ethnic groups in Africa for the management of hemorrhagic diarrhea, stomachache, respiratory tract infections, urinary tract infections coughs, hypertension and gonorrhea. This study was carried out to identify low molecular weight phytochemicals present in the root bark extract of M. aethiopicum with the aid of gas chromatography-mass spectrometry (GC-MS) technique. The...

Author(s): Mhuji Kilonzo, Patrick A. Ndakidemi and Musa Chacha

Phytochemical profile of stem bark extracts of Khaya senegalensis by Gas Chromatography-Mass Spectrometry (GC-MS) analysis

March 2017

The phytochemical constituents of stem bark extracts of Khaya senegalensis were isolated and analyzed using Gas Chromatography-Mass Spectrometry (GC-MS). A shade-dried stem bark of K. senegalensis was extracted using methanol and water as solvents. The main chemical compositions of the extracts were analyzed by GC-MS and preliminary phytochemical analysis was performed to confirm the various classes of active chemical....

Author(s): Celestine Uzoma Aguoru, Christopher Gbokaiji Bashayi and Innocent Okonkwo Ogbonna

Biochemical and antioxidants activity of crude, methanol and n-hexane fractions of Vernonia calvoana on streptozotocin induced diabetic rats

March 2017

This study is aimed at evaluating the biochemical effects and antioxidants activity of extracts of Vernoia calvoana Hook. f (V.C) on STZ induced diabetic rats. Thirty-six rats weighing (100 to 150 g), were divided into 6 groups of 6 animals each. Groups 1 and 2 representing normal and diabetic controls (NC and DC), respectively, receiving placebo, while groups 3 to 6 represented diabetic treated, receiving 500 mg/kg...

Author(s): Iwara Arikpo Iwara, Godwin Oju Igile, Friday Effiong Uboh, Kelvin Ngwu Elot and Mbeh Ubana Eteng

Antioxidant and hepatoprotective effect of Urtica Dioica extract against N-nitroso methyl urea induced injuries in mice

February 2017

The aim of this study is to investigate the antioxidant and protective effect of an aqueous extract from Urtica dioica on liver injuries, induced by one of the most potent dietary carcinogenic agents N- Nitroso methyl urea (NMU). Firstly, the free radical scavenging activity of U. dioica extract was assessed by measuring its capability to scavenge the radical 2,2-diphenyl-1-picrylhydrazyl (DPPH). Liver injury was...

Author(s): El Ouar Ibtissem, Tartouga Maya Abir , Loucif Oumayma Rokeya and Naimi Dalila,

Brown seaweeds administration generate psychotherapeutic response associated with brain norepinephrine modulation in rats

January 2017

Research in the area of herbal psychopharmacology has increased considerably over the past few decades in search of panacea for neuroprotection. Seaweeds are one of the herbal sources consumed in many Asian countries as medicine due to their remarkable bioprospecting properties and evident health benefits. Keeping in view the bioactive potential of seaweeds, the present study was designed to evaluate the...

Author(s): Adnan Khan, Nizam Uddin, Saima Khaliq, Shazia Nawaz, Munawwer Rasheed, Ahsana Dar, Muhammad Hanif and Pirzada Jamal Ahmed Siddiqui

Antibacterial and antifungal activities of leaf extracts of Phyllanthus amaru Schum and Thonn.

January 2017

The leaf extracts of Phyllanthus amarus Schum and Thonn. a common Western Nigerian weed, was investigated for phytochemical constituents and antimicrobial activities. Hexane extracts demonstrated the highest extraction of 59% followed by Acetone (57%) and water (48%). Saponins, tannins, alkaloid flavonoids, balsam, anthraquinones and phenols were extracted in an acidic medium. Twelve microorganisms (8 bacterial species...

Author(s): Senjobi, C.T., Ettu, A. O. and Otujo, C.O.

Chemical composition and anticancer activity of Achillea fragrantissima (Forssk.) Sch. Bip. (Asteraceae) essential oil from Egypt

January 2017

The aerial parts of Achillea fragrantissima (Forssk.) Sch. Bip., wildly grown in Egypt, yielded 0.8 and 1.5% (v/w) of essential oils prepared by hydrodistillation (HD), or by conventional volatile solvent extraction method (preparation of the “absolute”, SE), respectively.  The volatile components of this essential oil were determined by GC–MS analyses. Twenty eight compounds were identified in...

Author(s): Mouchira Aly Choucry

Preliminary bioactivity investigation of Styrax officinalis fruit extract as potential biopesticide

December 2016

Styrax officinalis is a deciduous large shrub that grows in many Mediterranean countries. Active ingredients are localized in the fruit pericarp. Primary phytochemical analysis showed the presence of saponins, tannins and triterpenes and absence of alkaloids and flavonoids. No antimicrobial, but strong ichthyotoxic and molluscicidal effects were observed in the saponin-rich extract .Toxicity tests with the snail Cornu...

Author(s): Robert Dib, Karim Makhoul and Rita Maalouf

Phytochemical and antioxidant studies of methanol and chloroform extract from leaves of Azadirachta indica A. Juss. in Tropical region of Nepal

December 2016

This research was carried out with the aim of phytochemical analysis and determining antioxidant activity present in methanol and chloroform leaf extracts of Azadirachta indica. Due to its potential in curing various ailments as well as wide spread application of antioxidant activity such as in the field of cosmetology, the plant was selected for the study. The total phenolics contained in the plant extracts were also...

Author(s): Dhakal S., Aryal P., Aryal S., Bashyal D. and Khadka D.

Antioxidant, hypolipidemic and preventive effect of Hawthorn (Crataegus oxyacantha) on alcoholic liver damage in rats

November 2016

The use of alcoholic beverages is more common and accepted by our society despite the health risks. Alcohol catabolism produces free radicals that cause oxidative stress and damage in liver principally. Hawthorn (Crataegus oxyacantha) is a medicinal plant that has been shown to have wide variety of polyphenolic compounds with antioxidant and hypolipidemic effect. The objective of this study was the evaluation of...

Author(s): José Luis Martínez-Rodríguez, Claudia Araceli Reyes-Estrada, Rosalinda Gutiérrez-Hernández and Jesús Adrián López

Evaluation of antioxidant and anti-tyrosinase activities as well as stability of green and roasted coffee bean extracts from Coffea arabica and Coffea canephora grown in Thailand

October 2016

Coffea arabica (Arabica) and Coffea canephora (Robusta) are the economic plants in Thailand that are widely cultivated in Northern and Southern Thailand. This study aims to evaluate the antioxidant, anti-tyrosinase activities, toxicity, stability and identify chemical components of the coffee bean extracts. The best extract that showed good biological activities will be further used to develop cosmeceutical products....

Author(s): Kanokwan Kiattisin, Thananya Nantarat and Pimporn Leelapornpisid

Amaranthus viridis modulates anti-hyperglycemic pathways in hemi-diaphragm and improves glycogenesis liver function in rats

October 2016

Amaranthus viridis is an ecumenical species in the botanical family of Amaranthaceae, which has been traditionally used to treat several skin diseases along with some antilipidemic activities. The present study was carried out to investigate the anti-hyperglycemic effect of 75% ethanolic extract of A. viridis in Neonatal streptozotocin (N-STZ) induced rats’ hemi-diaphragm, including screening for secondary plant...

Author(s): Shihab Uddin, Md. Mahmodul Islam, Md. Mynul Hassan, Amrita Bhowmik and Begum Rokeya

Effect of seasonal changes on the quantity of phytochemicals in the leaves of three medicinal plants from Limpopo province, South Africa

September 2016

The study was carried out to investigate the effect of seasonal changes on the quantity of phytochemicals in leaves of three medicinal plants: Barleria dinteri, Grewia flava and Jatropha lagarinthoides, collected from Limpopo province in South Africa. Three medicinal plants were collected during different seasons of the year and phytochemicals were quantified on plant samples collected in each season. Alkaloids and...

Author(s): S. S. Gololo, L. J. Shai, N. M. Agyei and M. A. Mogale

Essential oil constituents and in vitro antimicrobial activity of the root of Mondia whitei (Hook. F.) Skeels (Periplocaceae)

August 2016

The composition of the essential oil of the root of Mondia whitei was analysed by gas chromatography-mass spectrometry (GC/MS). The agar-well diffusion technique was used for the antimicrobial assay of the oil against nine clinical pathogenic organisms viz. Bacillus cereus, Escherichia coli, Candida albicans, Klebsiella pneumoniae, Pseudomonas aeruginosa, Proteus mirabilis, Salmonella typhi, Staphylococccus aureus and...

Author(s): Idayat T. Gbadamosi and Sherifat A. Aboaba

Comparative study between effects of ethanol extract of Zingiber officinale and Atorvastatine on lipid profile in rats

August 2016

Zingiber officinale is known for its cholesterol-lowering and antioxidant properties. The use of traditional medicine reduces the use of drugs with a risk of toxicity. This study aims to assess the effects of ethanol extract of Z. officinale and atorvastatin on lipid parameters in rats fed with high-fat diet. The experiment was carried out on 40 rats during 9 weeks. The animals were divided into 4 groups; group 1...

Author(s): Abdelkrim Berroukche, Abdelkrim Attaoui and Mustafa Loth

Anti-cancer efficacy of ethanolic extracts from various parts of Annona Squamosa on MCF-7 cell line

July 2016

Medicinal plant extracts are known to possess breast cancer antidote. The present investigation is focused on anticancer efficacy of various parts of Annona squamosa. The organic (ethanol) extracts from various parts of Annona squamosa were prepared using soxhlet apparatus and tested for in vitro anticancer efficacy on Breast cancer cell line MCF-7 by MTT (3-(4, 5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide)...

Author(s): Sneeha Veerakumar, Safreen Shaikh  Dawood Amanulla and Kumaresan Ramanathan,

Evaluation of anti-bacterial activity and bioactive chemical analysis of Ocimum basilicum using Fourier transform infrared (FT-IR) and gas chromatography-mass spectrometry (GC-MS) techniques

June 2016

The objective of this research was to determine the chemical composition of aerial parts extract from methanol. The phytochemical compound screened by gas chromatography-mass spectrometry (GC-MS) method. Thirty one bioactive phytochemical compounds were identified in the methanolic extract of Ocimum basilicum. The identification of phytochemical compounds is based on the peak area, retention time molecular weight,...

Author(s): Mohanad Jawad Kadhim, Azhar Abdulameer Sosa and Imad Hadi Hameed

Analysis of bioactive chemical compounds of Euphorbia lathyrus using gas chromatography-mass spectrometry and Fourier-transform infrared spectroscopy

May 2016

The aim of this study was determination the phytochemical composition of methanolic seeds extract of Euphorbia lathyrus. Gas chromatography-mass spectrometry (GC-MS) analysis of E. lathyrus revealed the existence of the Carbonic acid, (ethyl)(1,2,4-triazol-1-ylmethyl) diester, 1H-Pyrrole,2,5-dihydro-1-nitroso, Hexanal dimethyl acetal,  Isosorbide dinitrate, DL-Arabinose,...

Author(s): Azhar Abduameer Sosa, Suhaila Husaein Bagi, and Imad Hadi Hameed

Design and optimisation of novel Huperzine A analogues capable of modulating the acetylcholinesterase receptor for the management of Alzheimer’s disease

May 2016

This is a de novo drug design study that aimed to create novel structures based on the alkaloid Huperzine A, capable of inhibiting the acetylcholinesterase (AChE) enzyme ligand binding pocket (AChE_LBP) for the management of Alzheimer’s disease. The X-ray crystallographic model of the Torpedo Californica AChE complexed to Huperzine A was identified from the Protein Data Bank (PDB ID 1VOT). Molecular visualisation...

Author(s): Sara Bonavia and Claire Shoemake

The interaction between the gall wasp Leptocybe invasa and Eucalyptus camaldulensis leaves: A study of phyto-volatile metabolites

April 2016

A comparative study of the volatile terpene fraction isolated from the leaves of Eucalyptus camaldulensis attacked by the gall wasp (Leptocybe invasa) and from the healthy leaves of the plant was carried out using gas chromatography-mass spectrometry. A total of 59 components representing 89.13 and 88.6%, respectively, of their total volatile fraction contents were analyzed. Of these volatiles, 26 compounds with...

Author(s): Maged El-Sayed Mohamed

Study of chemical composition of Foeniculum vulgare using Fourier transform infrared spectrophotometer and gas chromatography - mass spectrometry

March 2016

Medicinal plants are potential sources of natural compounds with biological activities and therefore attract the attention of researchers worldwide. The objective of this research was to determine the chemical composition of seeds extract from methanol. The phytochemical compound screened by gas chromatography - mass spectrometry (GC-MS) method. Fifty six bioactive phytochemical compounds were identified in the...

Author(s): Hussein J. Hussein, Mohammed Yahya Hadi and Imad Hadi Hameed

Phytochemical screening of methanolic dried galls extract of Quercus infectoria using gas chromatography-mass spectrometry (GC-MS) and Fourier transform-infrared (FT-IR)

March 2016

The main objective of this study was to determine the phytochemical composition from the dried galls of Quercus infectoria, using methanolic extraction and report the main functional components by using infrared (IR) technique. The phytochemical compound screened by gas chromatography-mass spectrometry (GC-MS) method. Twelve bioactive phytochemical compounds were identified in the methanolic extract of Q. infectoria....

Author(s): Ameera Omran Hussein, Ghaidaa Jihadi Mohammed, Mohammed Yahya Hadi and Imad Hadi Hameed

Determination of metabolites products by Cassia angustifolia and evaluate antimicobial activity

February 2016

Phytochemicals are chemical compounds often referred to as secondary metabolites. Forty four bioactive phytochemical compounds were identified in the methanolic leaves extract of Cassia angustifolia. The identification of phytochemical compounds is based on the peak area, retention time molecular weight and molecular formula. Gas chromatography-mass spectrometry (GC-MS) analysis of C. angustifolia revealed the existence...

Author(s): Ali Hussein Al-Marzoqi , Mohammed Yahya Hadi and Imad Hadi Hameed

Analysis of bioactive chemical compounds of Nigella sativa using gas chromatography-mass spectrometry

February 2016

Phytochemicals are chemical compounds often referred to as secondary metabolites. Twenty eight bioactive phytochemical compounds were identified in the methanolic extract of Nigella sativa. The identification of phytochemical compounds is based on the peak area, retention time molecular weight, and molecular formula. Gas chromatography-mass spectrometry (GC-MS) analysis of Nigella sativa revealed the existence of the...

Author(s): Mohammed Yahya Hadi, Ghaidaa Jihadi Mohammed and Imad Hadi Hameed

In vitro antibacterial and antifungal activities of Chrysophyllum albidum and Diospyros monbuttensis leaves

January 2016

Despite progress in the development of antibacterial agents, there are still special needs to find new antibacterial agents due to the development of multidrug resistance by bacteria and fungi. This study was conducted to investigate and compare the in vitro antibacterial and antifungal activities of the methanolic and ethanolic extracts of the leaves of Chrysophyllum albidum and Diospyros monbuttensis. Methanolic and...

Author(s): Olasehinde Grace Iyabo, Okolie Zeluch Vianne, Oniha Margaret Ikhiwili, Adekeye Bosede Temitope and Ajayi Adesola Adetutu

Pharmacological studies of methanolic extracts of Sonchus arvensis from Kathmandu

December 2015

Sonchus arvensis, a perennial sowthistle, is a common but underutilized species of Kathmandu, Nepal. Several uses like sedative, antioxidant and kidney stone eradicating properties have been identified till date, but study on other pharmacological activities is not yet explored. Therefore, this plant was collected from Kathmandu; aerial parts of the plant were dried, crushed, and extracted using a Soxhlet apparatus. The...

Author(s): Bhupendra Kumar Poudel, Jagnnath Prasad Sah, Shyam Raj Subedi, Mohan Prasad Amatya, Sadhana Amatya and Tirtha Maiya Shrestha

Hepatoprotective effects of the decoction and macerated leaves of Rhamnus alaternus L. on rats exposed to carbon tetrachloride

October 2015

The plant of Ramnus alaternus L. (Rhamnaceae) has been object of many therapeutic indications for traditional medicine. Many studies have showed a hepatoprotective activity of R. alaternus L. The objective of this study was to compare the hepatoprotective activities of decoction and macerated R. Alaternus L. leaves extracts on rats initially exposed to carbon tetrachloride CCl4 (1 ml/kg). The macerated leaves (250 mg/kg...

Author(s): Abdelkrim Berroukche, Khaled Kahloula, Miloud Slimani, Imane Denai and Kheira Ammour

Phytochemical analysis of Urtica dioica leaves by fourier-transform infrared spectroscopy and gas chromatography-mass spectrometry

October 2015

Phytochemicals are chemical compounds formed during the plants normal metabolic processes. These chemicals are often referred to as secondary metabolites. The objective of this research was to determine the chemical composition of leaves extract from methanol. The phytochemical compound screened by gas chromatography-mass spectrometry (GC-MS) method. Fifteen bioactive phytochemical compounds were identified in the...

Author(s): Huda Jasim Al-Tameme, Mohammed Yahya Hadi and Imad Hadi Hameed

Determination of metabolites products by Penicillium expansum and evaluating antimicobial activity

September 2015

The objectives of this study were to analyze the secondary metabolites of Penicillium expansum and evaluate antibacterial activity. Twenty eight bioactive compounds were identified in the methanolic extract of P. expansum. The identification of bioactive chemical compounds is based on the peak area, retention time molecular weight and molecular formula. Gas chromatography mass spectrometry (GC/MS) analysis of P....

Author(s): Lena Fadhil Hamza, Sabreen A. Kamal and Imad Hadi Hameed

Evaluation of the anthelmintic activity of pumpkin seeds (Cucurbita maxima) in mice naturally infected with Aspiculuris tetraptera

September 2015

The aim of this study was to investigate the anthelmintic effect of pumpkin seeds (Cucurbita maxima) against Aspiculuris tetraptera in naturally infected mice.  For this purpose, the natural infection was determined by the cellophane tape (on the anal region), and the centrifugal flotation methods of stool samples in approximately 150 male Swiss albino mice (27 to 35 g). The infected mice (29 animals) were divided...

Author(s): Erol Ayaz, Cengiz Gökbulut, Hamit CoÅŸkun, Arzu Türker, Åžeyda Özsoy and Kübra Ceylan

Biochemical analysis of Origanum vulgare seeds by fourier-transform infrared (FT-IR) spectroscopy and gas chromatography-mass spectrometry (GC-MS)

September 2015

Medicinal plants are potential sources of natural compounds with biological activities, and therefore attract the attention of researchers worldwide. The objective of this research is to determine the chemical composition of methanolic seed extract. The phytochemical compound screened by spectroscopy and gas chromatography-mass spectrometry (GC-MS) method. Sixteen bioactive phytochemical compounds were identified in the...

Author(s): Huda Jasim Al-Tameme, Imad Hadi Hameed, Salah Ali Idan and Mohammed Yahya Hadi  

Analysis of bioactive chemical compounds of Aspergillus niger by using gas chromatography-mass spectrometry and fourier-transform infrared spectroscopy

August 2015

Bioactives are chemical compounds often referred to as secondary metabolites. Thirty five bioactive compounds were identified in the methanolic extract of Aspergillus niger. The identification of bioactive chemical compounds is based on the peak area, retention time molecular weight and molecular formula. Gas chromatography-mass spectrometry (GC-MS) analysis of Aspergillus niger revealed the existence of the...

Author(s): Imad Hadi Hameed, Lena Fadhil Hamza and Sabreen A. Kamal

Ethnobotanical survey of healing medicinal plants traditionally used in the main Moroccan cities

August 2015

The present study is a survey conducted to indicate the healing medicinal plants, traditionally used by the Moroccan population, and especially to select the healing plants mainly used in the form of essential oils. This survey allowed an inventory of 59 species of healing plants belonging to 37 families. The results showed that the whole plant is the most commonly used part (31%), followed by the leaves (29%). Most...

Author(s): Messaoudi Moussi I., Filali, H., Tazi, A. and Hakkou, F.  

Preliminary screening of anti-inflammatory effect of phytochemicals on chemotaxis of human neutrophils

August 2015

Neutrophils are leukocytes that are actively recruited to sites of tissue infection and/or injury by directed movement (chemotaxis). In vitro assessment of inhibition of neutrophil chemotaxis is a physiologic indicator of anti-inflammatory potential. To identify nontoxic, anti-inflammatory agents, plant-derived compounds (curcumin, resveratrol, rosmarinic acid and piperine) were assessed for effects on in vitro...

Author(s): Uthayashanker R. Ezekiel and Rita M. Heuertz

Identification of five newly described bioactive chemical compounds in methanolic extract of Mentha viridis by using gas chromatography - mass spectrometry (GC-MS)

July 2015

The bioactive compounds were screened by gas chromatography-mass spectrometry (GC-MS) method. Twenty one bioactive phytochemical compounds were identified in the methanolic extract of Mentha viridis using GC-MS method. The identification of phytochemical compounds is based on the peak area, retention time, molecular weight and molecular formula. GC-MS analysis of M. viridis revealed the existence of the...

Author(s): Imad Hadi Hameed, Hussein J. Hussein, Muhanned Abdulhasan Kareem, and Nidaa Shihab Hamad

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