Journal of
Pharmacognosy and Phytotherapy

  • Abbreviation: J. Pharmacognosy Phytother.
  • Language: English
  • ISSN: 2141-2502
  • DOI: 10.5897/JPP
  • Start Year: 2009
  • Published Articles: 215

JPP Articles

Bioactive compounds and antimicrobial potential of the roots extract of Anogeissus leiocarpa, a chewing stick used for oral care in Benin Republic

October 2020

Chewing stick are still used in developing countries for oral hygiene in other to prevent oral diseases. But still, few is known about their phytochemical potential and antimicrobial activity. The present work was devoted to one of these plants used in the Republic of Benin, namely the root of Anogeissus leiocarpa. 2,2-Diphenyl-1-picrylhydrazyl (DPPH) and ferric reducing antioxidant power (FRAP) methods were used for...

Author(s): Olayé Théophile, Tchobo Fidèle Paul, Chabi Nicodème, Koudokpon Hornel, Amoussa Abou Madjid Olatoundé, Lagnika Latifou,  Alitonou Alain Guy, Avlessi Félicien and Sohounhloué Dominique  

Uncaria guianensis (Aubl.) J.F. Gmel. extracts reduce bronchial hyper responsiveness and inflammation in a murine model of asthma

October 2020

Uncaria guianensis (Aubl.) J. F. Gmel. (“cat’s claw”, Rubiaceae) is a plant with potential to treat asthma because of its anti-inflammatory and antioxidant activities. The aim of this study was to evaluate the effects of two extracts of U. guianensis in an animal model of allergic asthma. Balb/c mice were sensitized twice with ovalbumin intraperitoneally one week apart, then challenged with intranasal...

Author(s): Leandra da Silva Zanetti, Andiamira Cagnoni Balestra, Jowanka Amorim, Fernando Silva Ramalho, Carlos Wagner de Souza Wanderley, João Paulo Mesquita Luiz, Piero Giuseppe Delprete, Ana Maria Soares Pereira, Marcos de Carvalho Borges and Fabio Carmona  

Phytochemical screening and antimicrobial activities of hydroethanolic extracts from leaves and roots of Cochlospermum planchonii (Bixaceae)

October 2020

Cochlospermum planchonii is traditionally used in Togo in treating several diseases, including burn wounds which achievement requires anti-infective and good cicatrisation processes. This study aims to evaluate the antimicrobial properties of hydroethanolic extracts from leaves and roots of C. planchonii and its phytochemical composition. Five (05) bacterial strains were suspended in liquid media with plant extracts at...

Author(s): Nakpane Fankibe, Kossi Metowogo, Yendube T. Kantati, Yaovi-Gameli Afanyibo, Povi Lawson-Evi, Aklesso Mouzou, Kwashie Eklu-Gadegbeku and Kodjo A. Aklikokou

In-ovo biological activity of Boswellia dalzielii stem bark extract and fractions against Newcastle disease virus

August 2020

Newcastle disease remains a disease of global concern and serious economic challenge to the poultry industry because of its high mortality rate, in spite of the various intervention programs including vaccination. This research is aimed at studying the antiviral activity of the extract and fractions of Boswellia dalzielii against Newcastle disease virus (NDV) using chicken embryonated eggs. Phytochemical analysis was...

Author(s): Temitayo Lucia Ohemu Abubakar Ahmed, Taiwo Emmanuel Alemika, Solomon Chuwang Chollom, Thomas Philip Yakubu, Dalen Gwatau Dafam, Victoria Akpidi Okwori and Nanle Josephine Damos  

Hypoglycaemic activity of preheated (roasting) Aframomum citratum (C. Pereira) K. Schum and Tetrapleura tetraptera (Schumach & Thonn.) fruits beverage on Streptozotocin-induced rats

May 2020

Tetrapleura tetraptera and Aframomum citratum fruits are used as spices and in the traditional pharmacopeia in Cameroon. They are mostly combined and preheated for many purposes while cooking. The effects of roasting on the phenolic content of spices, phenolic profile of a beverage made with the mix of roasted spices and its hypoglycaemic activity on diabetes complications were investigated. Aqueous extract (infusion:...

Author(s): Eyenga Manga, Takuissu N. G. R., Ziyyat A., Ngondi J. L. and Sindic M.,  

Phytochemical profiling, body weight effect and anti-hypercholesterolemia potentials of Cnidoscolus aconitifolius leaf extracts in male albino rat

April 2020

The present study investigated the phytochemical constituents of Cnidoscolus aconitifolius leaves extracts and its anti-hypercholesterolemia potentials using standard analytical methods. Forty five male albino rats weighing (115-121 g), divided into nine groups of five rats were used.  Group I served as the control while the other groups were administered 200, 400, 600 and 800 mg/kg body weight of aqueous and...

Author(s): Chukwu, Ezinne.C., Osuocha, Kelechi U., Iwueke, Adaku V    

Antioxidant and alpha amylase inhibitory activity of Nepalese medicinal plants from Gorkha district

April 2020

The aim of this study is to evaluate the antioxidant activity, α-amylase inhibition activity, estimation of total phenolic and flavonoid content and the toxicity in ten medicinal plants Woodfordia fructicosa, Tectaria coadunate, Prunus cerasoides, Abrus precatorius, Eclipta prostrate, Poranopsis paniculata, Chenopodium album, Oroxylum indicum, Curcuma caesia, and Butea monosperma collected from Gorkha District of...

Author(s): Junita Rai, Khaga Raj Sharma and Yuba Raj Pokharel  

Macroscopic and microscopic features of diagnostic value for Warburgia ugandensis Sprague leaf and stem-bark herbal materials

April 2020

Warbugia ugandensis is among the ten most utilized medicinal plants in East Africa. Stem-bark and leaves are used as remedies for malaria, stomachache, coughs and several skin diseases. Consequently, the plant is endangered because of uncontrolled harvest from the wild and lack of domestication. There is therefore fear of poor quality commercialized products due to lack of quality control mechanisms. The objective of...

Author(s): Onyambu Meshack Ondora, Nicholas K. Gikonyo, Hudson N. Nyambaka and Grace N.Thoithi  

Phytochemical analysis, antioxidant and antidiarrhoeal activities of methanol extract of Fimbristylis miliacea (L.) Vahl

March 2020

The present study determined phytochemical content, antioxidant and antidiarrhoeal effect of methanol extract of Fimbristylis miliacea. Phytochemical screening showed the presence of flavonoids, saponins, tannins, phenols, alkaloids and cardiac glycosides. Total phenolic, flavonoids, flavonols, tannins, β-carotene, lycopene, chlorophyll-α, and chlorophyll-β contents were found 154.13 mg GAE/g, 83.14 mg...

Author(s): Ummah Hafsa Mukta#, Roni Roy#, A. F. M. Shahid Ud Daula, Mahmuda Ferdous, Anwesha Chowdhury, Sohel Mia, Afroza Akter, Israt Jahan Liya and Mohammad Anwarul Basher  

Review on biological and immunomodulatory properties of Moringa oleifera in animal and human nutrition

February 2020

Moringa oleifera, also called "miracle tree" or "tree for life" is a tree native from India. Highly resistant to drought, M. oleifera grows very well in tropical regions, including Benin. It is a plant with very high nutritional values. The different parts of the plant (leaves, fruiots, seeds, roots, bark and flowers) have multiple uses, both therapeutic and nutritional, with uses in human and...

Author(s): Adouko S. Jacques, Soha S. S. Arnaud, Ohouko O. H. Fréjus and Dougnon T. Jacques  

Pharmacognostic, physicochemical and phytochemical evaluation of the leaves of Fadogia cienkowski Schweinf (Rubiaceae)

October 2019

Fadogia cienkowskii is a shrub used in folklore medicine. Evaluations of the leaves were carried out to determine the macroscopic, microscopic, chemomicroscopic, physicochemical and phytochemical profiles using standard methods. The macroscopic examination revealed fresh leaves are green, odourless with a bitter taste. The leaf is oblong-elliptic in shape and sub-acute at apex; rounded at the base with entire margin....

Author(s): Bruce S. O., Onyegbule F. A. and Ezugwu C. O.  

Tea tree oil a new natural adjuvant for inhibiting glioblastoma growth

October 2019

Tea Tree oil (TTO), the essential oil from the Australian native Melaleuca alternifolia has demonstrated a variety of beneficial efficacies including antimicrobial, antifungal, antiviral and anti-inflammatory. This report discusses data obtained on the in vitro activity of TTO on human glioblastoma cells U87MG. Cell viability was examined by 2-(4,5-dimethyl-2-thiazolyl)-3,5-diphenyl-2H-tetrazolium bromide MTT assay....

Author(s): Antonietta Arcella, Maria Antonietta Oliva, Sabrina Staffieri, Massimo Sanchez, Michele Madonna, Salvatore Castaldo, Felice Giangaspero, and Luigi Frati,  

A comparative study of phytochemical profile and antioxidant activity of Sahelian plants used in the treatment of infectious diseases in northern part of Burkina Faso: Acacia seyal Delile and Acacia tortilis (Forssk.) Hayne subsp. raddiana (Savi)

October 2019

Acacia seyal and Acacia tortilis are used in the treatment of infectious diseases in traditional medicine by population in Northern Burkina Faso. Phytochemical screening by tube test and on HPTLC plates showed the presence of important chemical compounds in these plants. Determination of total phenolic content using method of Folin-Ciocalteu Reagent (FCR) and antioxidant activity by 1, 1-diphenyl-2-picrylhydrazyl (DPPH)...

Author(s): Alphonsine RAMDE-TIENDREBEOGO, Moumouni KOALA, Nabere OUATTARA, Marius LOMPO and Innocent Pierre GUISSOU  

Phytochemistry, acute toxicity and blood profile of albino rats treated with fruit extract of Solanum macrocarpon

September 2019

Phytochemical screening of the methanolic fruit extract of Solanum macrocarpon was performed using standard method. Eighteen male albino mice, assigned into six groups (n=3) were used to determine the acute toxicity (LD50) of the extract. Haematological effect of the extract was determined using forty eight adult male rats assigned into four groups (A-D; n=12). The treatment groups received daily oral administration of...

Author(s): MBEGBU Edmund Chidiebere, EZECHUKWU Chiemekam Samuel, EJERE Vincent Chikwendu, NNAMONU Emmanuel Ikechukwu and UGWU Godwin Chigozie  

The effect of blending of extracts of Sudanese Adansonia digitata and Tamarindus indica on their antioxidant, anti-inflammatory and antimicrobial activities

August 2019

Adansonia digitata (Bombacaceae) and Tamarindus indica (Fabaceae) are the most popular herbal products in Sudan; they are used as food ingredients and in traditional treatments of various diseases. The aim of this study is to investigate phytochemical contents, antioxidant, anti-inflammatory and antimicrobial activities of plants fruit, leaf and bark ethanolic extracts. The phytochemical screening of different extracts...

Author(s): Ayat Ahmed Alrasheid, Shimaa AbdelRahman Ahmed, Sahar Hussein Eltilib,  Mawa Ibrahim Alnour, Marvit Osman Widdatallh, Layla Fathi Yassin, Kowther Isam Eldein, Einas Gamal Mohieldin, Alaa Abdulmoneim Mohamed and Saad Mohamed Hussein Ayoub  

Immunomodulatory activities of polysaccharides isolated from plants used as antimalarial in Mali

August 2019

Medicinal plants used against malaria in Mali have previously been tested for their antiplasmodial activities using their organic solvent and water extracts. As the healers mainly use the water extracts for their treatments of malaria-patients, our aim was to study the water-soluble components from Malian plants used for treatment of malaria. Argemone mexicana (aerial parts), Sarcocephalus latifolius (root bark), Vitex...

Author(s): Adama Dénou,, Adiaratou Togola, Kari Tvete Inngjerdingen, Bing-Zhao Zhang, Abubakar Ahmed, Dalen Gwatau Dafam, John C.Aguiyi Rokia Sanogo, Drissa Diallo, and Berit Smestad Paulsen  

UHPLC-DAD characterization of bioactive secondary metabolites from Ocimum americanum and Pupalia lappacea extracts: Antioxidant activity and antihypertensive effects on L-NAME-induced hypertensive rats

July 2019

Ocimum americanum L. (Lamiaceae) and Pupalia lappacea (L) Juss. (Amaranthaceae) are two plants used in Bénin to manage hypertension. Little scientific data is available on the antihypertensive properties of these plants. Therefore, we investigated the antihypertensive potential of ethanolic extracts of O. americanum and P. lappacea on L-NAME-induced hypertensive rats. The DPPH free radical scavenging potential,...

Author(s): Adjileye Rafatou  Adédoyin Adjokè, Amoussa Abdou Madjid Olatoundé, Rafiou Adamou, Awede Bonaventure, Laleye Anatole and Lagnika Latifou  

Phytochemical investigation and assessment of antimicrobial, anti-inflammatory and antioxidant activities of Sudanese Citrus paradisi peel extract

January 2019

The peel of grape fruit is used in traditional medicine for the treatment of several diseases. The objective of this study was to evaluate the antimicrobial, anti-inflammatory and antioxidant activities of peel extract from Citrus paradisi. Qualitative phytochemical screening of peel indicates the presence of alkaloids, flavonoids, sterols, triterpenes, tannins, saponins, coumarins, glycosides, reducing sugars,...

Author(s): Ayat Ahmed Alrasheid, Alaa Abdulmoneim Mohamed, Einas Gamal Mohieldin, Kowther Isam Eldein, Layla Fathi Yassin, Marvit Osman Widdatallh, Mawa Ibrahim Alnour, Sahar Hussein Eltilib, Shimaa AbdelRahman Ahmed and Saad Mohamed Hussein Ayoub  

Ethnobotanical survey of plants traditionally used for malaria prevention and treatment in indigenous villages of Tepi Town South West Ethiopia

January 2019

Increased resistance to insecticides and established drugs by malaria vectors necessitate the search for alternative cost-effective malaria control tools in the Ethiopia. Traditional remedies are the most important source of therapeutics of the population and more than 85% of the traditional medical preparations in Ethiopia are of plant origin. As the Ethiopian indigenous medicinal plants' knowledge and diversity is...

Author(s): Dagne Abebe and Belachew Garedew  

Phytochemical screening, antioxidant and cytotoxic activity of different morphotypes of Corchorus olitorius L. leaves in the central region of Benin Republic (West Africa)

December 2018

Corchorus olitorius L. which belongs to Tiliaceae family is a cultivated herbaceous plant highly consumed as traditional leafy vegetables in Benin. Extracts from samples of different morphotypes leaves of this species were analysed for their phytochemical compositions, antioxidant and cytotoxicity activities. On each sample extract, qualitative phytochemical tests were used to detect the presence of bioactive molecules...

Author(s): Adjatin A., Hounkpatin A. , Assogba F., Djengue W., Agbotta P., Bénindicte H., Dansi A., Gbenou J. and Amouzou K. S.  

High performance liquid chromatography-diode array detection (HPLC-DAD) profiling, antioxidant and anti-proliferative activities of ethanol leaf extract of Berlinia grandiflora (Vahl) Hutch. & Dalziel

November 2018

Berlinia grandiflora is used for managing numerous ailments including tumor in South-west, Nigeria. The phytochemical contents, antioxidant and antiproliferative activities of B. grandiflora leaf were determined in this study. The absolute ethanol extract was evaluated by high performance liquid chromatography-diode array detection (HPLC-DAD). The antioxidant activity was carried out by standard analytical methods. The...

Author(s): Aliyu Adamu, Kevwe Benefit Esievo, Grace Ugbabe, Samuel Ehiabhi Okhale and Henry Omoregie Egharevba

Catechins as antidiabetic compounds of Bridelia ferruginea Benth root bark extract

October 2018

The present study was carried out to evaluate the antidiabetic activity of catechins isolated from Bridelia ferruginea in previous studies. Epigallocatechin (EGC) and Epigallocatechin gallate (EGCG) isolated from B. ferruginea were administrated to streptozotocin-induced diabetic mice to evaluate their anti-hyperglycemic and anti-hyperlipidemic effects. Then, biochemical parameters were assayed in different groups of...

Author(s): Batomayena Bakoma, Bénédicte Berké, Aboudoulatif Diallo, Kwashie Eklu-Gadegbeku, Kodjo Aklikokou, Messanvi Gbeassor, and Nicholas Moore  

Clinopodium nubigenum (Kunth) Kuntze essential oil: Chemical composition, antioxidant activity, and antimicrobial test against respiratory pathogens

September 2018

The essential oil of leaves and flowers of Clinopodium nubigenum (Kunth.) Kuntze (Lamiaceae) collected in the province of Pichincha-Ecuador was steam distilled and analyzed by gas chromatography mass spectrometry (GC/MS) to determine its chemical composition. The majority of the compounds identified were carvacrol acetate (42.1%), carvacrol (20.6%), pulegone (6.3%) and thymol (5.5%). Antioxidant activity was assessed by...

Author(s): Paco Fernando Noriega, Tatiana de Los Ángeles Mosquera, Edison Antonio Osorio, Pablo Guerra and Andrea Fonseca

Anti-inflammatory property of the methanol leaf extract of Parinari kerstingii (ENGL) in rats

September 2018

The anti-inflammatory effect of the extract of Parinari kerstingii leaves was investigated using egg albumin-induced rat paw oedema, leukocyte mobilization, and acetic acid-induced vascular permeability assay methods. Heat and hypotonicity-induced heamolysis of human red blood cell membrane were also used to assess its membrane stabilizing effect and to determine its inhibitory property on phospholipase A2 activity....

Author(s): Odu Nwamaka Maureen, Tchimene Kenne Michel, Ogugua Victor Nwadiogu, ObongaWilfred, Sunday Patrick Gaza Anze and Nwanguma Bennett Chima  

Genotoxic effects of Peganum harmala L. in relation to traditional use

September 2018

Peganum harmala L. is a well-known medicinal plant, widely distributed and used in folk medicine. Recently, numerous reports have been published regarding the pharmacological and therapeutic effects of P. harmala and its major alkaloids components. However, mammalian toxicity due to P. harmala alkaloids extract has been rarely investigated. The present research aimed to study the genotoxic effects of harmala plant...

Author(s): Salim M. Abderrahman, Sameh Soliman and Mohammad G. Mohammad  

In vitro anticancer screening of Colombian plants from Piper genus (Piperaceae)

September 2018

Historically, knowledge of ethnobotany, which has revealed different phytochemical and pharmacological compounds from traditional plants, has formed the basis for new anticancer drug discovery. The use of some Piper species in traditional medicine against cancer, suggests that genus Piper is a promising source of new compounds with anticancer activity. A total of 28 ethanolic extracts were obtained from 16 different...

Author(s): Diego R. Muñoz, Adrián G. Sandoval-Hernandez, Wilman A. Delgado, Gonzalo H. Arboleda and Luis E. Cuca  

Evaluation of the therapeutic and toxicological knowledge of herbalists on the most notified plants in the poison control and pharmacovigilance center of Morocco

August 2018

According to the World Health Organization, 80% of the population in developing countries is engaged in traditional medicine. Consequently, the issue of poisoning by plants is not negligible. The objective of this study is to evaluatethe therapeutic and toxicological knowledge of herbalists of the most reported plants in the anti-poison center of Morocco. Field study by direct interview with 20 herbalists of the...

Author(s): Imane Zakariya, Jihane Ifezouane, Amal Addaoui, Souad Skalli and Yassir Bouslimane

The Mexican mistletoe Struthanthus venetus (HBK Blume) inhibits proliferation and synergizes antagonistic actions of Tamoxifen and Fulvestrant in breast cancer MCF-7 cells

August 2018

Mistletoes are hemi-parasitic plants widely distributed around the world, used in folk medicine to treat many diseases including diabetes, hypertension, menopausal syndrome and as complementary or adjuvant treatment for cancer. The objective of the present work was the evaluation of oestrogenic activity of hydromethanolic extract of mistletoe Struthanthus venetus dried leaves (StvHME), to evaluate its potential benefits...

Author(s): Marte Lorenzana-Jiménez, María Estela Avila, Alejandra Figueroa, Lorena Mendiola-Almaraz, Gil Alfonso Magos Guerrero and Cristina Lemini  

Protective effect of ethanolic extract of Cucurbita maxima (PUMPKIN) leaf on acetaminophen-induced acute liver toxicity

August 2018

Ethanolic extract of dried leaves of Cucurbita maxima (Pumpkin) were screened for their phytochemical composition. The in vitro antioxidant property was determined by assessing the free radical (DPPH) scavenging activity. Twenty rats divided into four groups were used for this study with group 4 pre-treated with the extract and later intoxicated with 2 g/kg single dose of acetaminophen. The hepatoprotective effect of...

Author(s): Michael Okey Enemali, Titilayo Oluwayemisi Bamidele and Mohammed Abdullahi Ubana

Pulcandi a healing natural ash coal against gastric acidity: Scientific comprehension

July 2018

As a coal, Pulcandi possesses the property of removing excess gastric and intestinal gas. Pulcandi powder has anti-diarrhea activity by decreasing intestinal fluid content and adsorbing microbes and toxins. The aim of this study was to demonstrate and to establish consequences of Pulcandi powder use on gastric acidity. For evaluating these consequences, it was investigated in vitro kinetic tests on acidity. These tests...

Author(s): Akpalo Edéfia, Aba Eklu Gudrun, Awaga  Kwami Lumo and Aba Eklu Abatévi

Comparative evaluation of the protective effect of leaf extracts of Vernonia amygdalina (bitter leaf) and Ocimum canum (curry) on acetaminophen induced acute liver toxicity

July 2018

The quest for alternate medicine in preventing and combating hepatotoxicity led to the screening of aqueous and ethanol extracts of dried leaves of Vernonia amygdalina Delile (bitter leaf) and Ocimum canum Linn (curry leaf) for phytochemicals and in vitro antioxidant properties. Some rats were pretreated with the extracts and later administered with 2g/kg of body weight single dose of acetaminophen and the...

Author(s): Michael Okey Enemali and Stanley Chidi Udedi  

Fungal metagenomes in polyherbal medicines used for the treatment of tuberculosis

June 2018

The traditional systems of medicine have significantly become more accepted in the developed and developing countries due to their curative property, less toxicity and minimal side effects. However, several studies have shown that they are associated with microbial contaminants. This study aimed at identifying fungi in nine polyherbal medicines used for the treatment of tuberculosis in Eastern Cape Province, South...

Author(s): Elizabeth Bosede Famewo, Anna Maria Clarke and Anthony Jide Afolayan

Ethnopharmacological studies of plants used for the treatment of rheumatic affections in Ouagadougou, Burkina Faso

May 2018

Plants are a considerable source of active substances which are exploited in the treatment of several diseases, among which are rheumatic affections. This study aimed to explore the knowledge of traditional practitioners and patients on medicinal plant species of Ouagadougou, Burkina Faso, used for the treatment of rheumatic affections. Direct interviews with open-ended and closed-ended questionnaires were used to...

Author(s): Estelle Noëla Hoho Youl, Joëlle W. Stephanie Tiendrebeogo, Fasteylah Y. Hounlidji, Frank Edgard R. Zongo, Aminata Nacoulma, Innocent Pierre Guissou and  Dieu-Donné Ouedraogo  

Pharmacognostic evaluation of the leaf of Microtrichia perotitii DC. (Asteraceae)

April 2018

Microtrichia perotitii DC. belongs to the family Asteraceae (Compositeae) and it is a herb found in the West African countries. The aim of this research was to establish pharmacognostic standards for M. perotitii through macroscopic, microscopic, chemo-microscopic and physico-chemical investigations. The macroscopic studies revealed the shape of the leaf as small with acute apex, asymmetric base, pubescent surface with...

Author(s): Abdullahi, M. N., Ilyas, N., Hajara, I. and Kabir, Y. M.  

Effect of Ethiopian high land green tea (Camellia sinensis) leaf extract on highly active anti-retroviral therapy induced dyslipidemia in Albino Wistar rats

April 2018

Highly active antiretroviral therapy (HAART) is considered toxic and has other life-threatening side effects including dyslipidemia. There is no research report on the health effects of Ethiopian highland green tea. Previous work data from elsewhere suggest that lipid abnormalities are associated with cardiovascular morbidity and mortality. The aim of this study was to investigate the possible protective effect of green...

Author(s): Tesaka Wondimnew, Natesan Gnanasekaran and Solomon Genet  

Antimicrobial activities from extracts of seven medicinal plant species against multidrug-resistant bacteria and fungi

March 2018

This is the first to report the antimicrobial effects of extracts of seven endemic medicinal plants. Flower extracts of Onopordum jordanicolum exhibited antibacterial activity against Staphylococcus aureus, MRSA, Klebsiella pneumonia, and Proteus mirabillis. Ethanol extract displayed significant antibacterial activity against S. aureus with the best MIC and MMC values. Onopordum blancheanum flower extracts produced...

Author(s): Maher Obeidat

The impact of seasonal variation on the volatile oil profile of leaves of Severinia buxifolia (Poir.) and its antimicrobial activity

March 2018

The effect of the time of collection on the quality and quantity of the oil obtained from Severinia buxifolia leaves as well as its antimicrobial activity was studied. The chemical composition of the hydro-distilled oils of the leaves of S. buxifolia (Poir.)Tenore, collected at the four seasons was determined by GC/MS analysis. Moreover, antimicrobial activity was studied, for the oil sample regarding the yield and...

Author(s): Safaa A. Nour, Mostafa A. Abdel Kawy, Maha M. Salama, and Mohamed S. Hifnawy  

Ethnobotanical study of medicinal plants used to treat human ailment in Guduru District of Oromia Regional State, Ethiopia

March 2018

This research was carried out to document ethnobotanical data and threats affecting medicinal plants. Semi-structured interviews, questionnaires, face to face discussion, and field visit was employed to gather the required data. A total of 92 informants 21 key and 71 randomly selected informants), of which 48 males and 44 females were used. The study documented 57 plants species which belongs to 55 genera and 41...

Author(s): Abiyot Tadesse, Birhanu Kagnew,  Firew Kebede and Mulugeta Kebede    

Anticancer activities and safety evaluation of selected Kenyan plant extracts against breast cancer cell lines

February 2018

Breast cancer is a leading cause of deaths among women suffering from cancer in Kenya. The current study was done to determine anticancer activities of medicinal plant extracts against breast cancer cell lines (HCC 1395 and 4T1). Vero cells were used for evaluation of safety of extracts. Thiazoly blue tetrazolium bromide (MTT) assay was used in this study. Reference drugs were 5 fluorouracil and cyclophosphamide....

Author(s): Onyancha Jared M., Gikonyo Nicholas K., Wachira Sabina W., Mwitari Peter G. and Gicheru Michael M.

Pharmacognosy and phytochemical standardization of Albizia Ferruginea (Guill and Perr) pulps

February 2018

In Africa and Cameroon in particular, people tend to use medicinal plants as the first approach to cure their illness or disease. In order to improve the safety and the progressive integration of those plants in our health systems, it is important to set a system and protocol that would permit an easy characterization, quality and safety control of medicinal plants through a standardization of their recipes. Thus, we...

Author(s): Rose Ngono Mballa Abondo, Aude P´erine Minyem Ngombi, Joseph Ngoupayo, Bonaventure Ngadjui Tchaleu and Beyeme Fridoline-Victorine

Diterpenes of the pimarane type isolated from Viguiera arenaria: Promising in vitro biological potential as therapeutic agents for endodontics

February 2018

Viguiera arenaria, family Asteraceae, is a plant that contains diterpenoids, which make this species potentially applicable in endodontics. More specifically, V. arenaria contains diterpenes of the pimarane type, which display various classic biological activities. This study evaluates the antibiofilm activity, the time-kill curve, and the inhibitory concentration index of diterpenes of the pimarane type...

Author(s): Soraia Marangoni, Thais da S. Moraes, Susane H. Utrera, Luciana A. Casemiro, Maria G. M. de Souza, Pollyanna F. de Oliveira, Rodrigo C. S. Veneziani, Sérgio R. Ambrósio, Denise C. Tavares and Carlos H. G. Martins

Amelioration potentials of Vernonia calvaona ethanol leaf extract in paracetamol-treated rats

January 2018

Paracetamol toxicity due to overdose amongst people living in the developing countries has been on the increase. This study investigated the amelioration potentials of Vernonia calvaona ethanol leaf extract in paracetamol-treated rats. Thirty five Wistar rats were divided into five groups of seven rats each. Hepatic damage was induced by administering 2 g/kg b.wt of paracetamol p.o for four day to all the groups except...

Author(s): Eyong Ubana Eyong, Godwin Eneji Egbung and Victor Ndubuisi Ndiodimma

Chemical composition and in vitro investigation of biological activities of Hemizygia bracteosa (Benth.) Briq leaves

January 2018

Hemizygia bracteosa (Benth.) Briq (Lamiaceae) is used in the treatment of mental disease, memory loss, HIV, malaria and had antimicrobial and hypoglycemic properties. To the authors’ knowledge, no scientific study has been done on these properties except antimicrobial and hypoglycemic properties. The phytochemical investigation focused on the quantification of phenolic compounds, flavonoids, tannins, anthocyanins...

Author(s): Marthe Dominique Chodaton Zinsou, Fidèle M. Assogba, Fernand Gbaguidi and Mansourou Moudachirou

Phytochemical and biological analyses of Citharexylum spinosum

December 2017

The phytochemical screening of Citharexylum spinosum L. aerial parts resulted in the presence of flavonoids, tannins, carbohydrates and/or glycosides, triterpenes and/or sterols and saponins. The percentage of hydrocarbons and sterols in C. spinosum petroleum ether extract were 99.57 and 0.3%, respectively. In petroleum ether extract, saturated fatty acids (78.76%) and unsaturated fatty acids (9.14%) were found....

Author(s): Amel M. Kamal, Mohamed I. S. Abdelhady#, Heba Tawfeek#, Maha G. Haggag# and Eman G. Haggag#

Phytochemical analysis, antioxidant and antimicrobial activities of leaves and flowers ethyl acetate and n-butanol fractions from an Algerian endemic plant Calycotome spinosa (L.) Link

December 2017

Calycotome spinosa (L.) Link is one of the important plants in traditional medicine especially in Algeria. The present work deals with the phytochemical screening, the flavonoids extraction from leaves and flowers of this plant, the quantification of total polyphenols and flavonoids, as well as the evaluation of antioxidant and antimicrobial properties of ethyl acetate and n-butanol fractions. While, the rest,...

Author(s): Radia Cherfia, Mounira Kara Ali, Imen Talhi, Akila Benaissa and Noreddine Kacem Chaouche

Evaluation of some biological activities of Trigonella hamosa aerial parts

November 2017

The antimicrobial activity of T. hamosa aerial parts extract against Bacillus subtilis, Staphylococcus aureus, Enterococcus fecalis, Escherichia coli, Pseudomonas auregenosa, Candida albicans, Fusarium sp. and Aspergilus niger was evaluated by disc diffusion method. The minimum inhibitory concentrations (MICs) for susceptible test microorganisms were further determined. Also the antioxidant and α-amylase...

Author(s): Sameer H. Qari and Nayer M. Fahmy

Ethnobotanical survey of plants used in the management of mental illnesses in some selected local government areas of Plateau State, Nigeria

October 2017

Mental illness refers to all diagnosable mental disorders which are characterised by abnormalities in thinking, feelings or behaviours. Ethnobotanical study surveyed the different types of medicinal plants used for the treatment of mental illness in Bassa, Pankshin, and Kanke Local Government Areas of Plateau State, Nigeria. Information was obtained from traditional medicine practitioners, herbalist and herb sellers,...

Author(s): Ior L. D., Otimenyin S. O., Okwori V. A., Umar D. M. and Azila J. J.

Pharmacognostic evaluation of the leaves and roots of Cassia sieberiana DC.

October 2017

Cassia sieberiana DC. (Leguminosae - Caesalpinioideae), commonly known as drumstick and ‘aridantooro’ in Yoruba, is a perennial tree native to Africa. It is used in ethno-medicine to manage arthritis and rheumatism. Pharmacological activities such as myorelaxant, antispasmodic, anti-inflammatory, and antimicrobial have been reported in literature. Pharmacognostic investigation including microscopy,...

Author(s): Fatokun Omolola T., Esievo Kevwe B., Ibrahim Jemilat A. and Kunle Oluyemisi F.

Antioxidant potential and cytotoxicity of Randia dumetorum Lam. leaf extract

September 2017

The aim of the current study was to explore the antioxidant potential and cytotoxicity of different ’fractions from the leaf extract of Randia dumetorum. Proximate analysis and phytochemical screening were done with standard protocol. The antioxidant activity was evaluated by using reducing power assay, total antioxidant capacity determination, determination of total phenolic content, determination of total...

Author(s): Abdullah-Al-Ragib, Md. Tanvir Hossain, Javed Hossain and Md. Jakaria,

Phytochemical and zootechnical studies of Physalis peruviana L. leaves exposured to streptozotocin-induced diabetic rats

August 2017

This is a phytochemical and zootechnical study on Physalis peruviana leaves in streptozotocin induced diabetic rats. This was part of a scientific development program of plant resources used in Congolese traditional medicine for the treatment of diabetes mellitus in which individual and community consequences are well established. Different fractions with hexane, ethyl acetate and the residue were obtained from the...

Author(s): C. N. Fokunang, F. K. Mushagalusa, E. Tembe-Fokunang, J. Ngoupayo, B. Ngameni, L. N. Njinkio, J. N. Kadima, F. A. Kechia, B. Atogho-Tiedeu, W. F. Mbacham and B. T. Ngadjui

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