Journal of
Pharmacognosy and Phytotherapy

  • Abbreviation: J. Pharmacognosy Phytother.
  • Language: English
  • ISSN: 2141-2502
  • DOI: 10.5897/JPP
  • Start Year: 2009

JPP Articles

September 2018

Clinopodium nubigenum (Kunth) Kuntze essential oil: Chemical composition, antioxidant activity, and antimicrobial test against respiratory pathogens

The essential oil of leaves and flowers of Clinopodium nubigenum (Kunth.) Kuntze (Lamiaceae) collected in the province of Pichincha-Ecuador was steam distilled and analyzed by gas chromatography mass spectrometry (GC/MS) to determine its chemical composition. The majority of the compounds identified were carvacrol acetate (42.1%), carvacrol (20.6%), pulegone (6.3%) and thymol (5.5%). Antioxidant activity was assessed by...

Author(s): Paco Fernando Noriega, Tatiana de Los Ángeles Mosquera, Edison Antonio Osorio, Pablo Guerra and Andrea Fonseca

September 2018

Anti-inflammatory property of the methanol leaf extract of Parinari kerstingii (ENGL) in rats

The anti-inflammatory effect of the extract of Parinari kerstingii leaves was investigated using egg albumin-induced rat paw oedema, leukocyte mobilization, and acetic acid-induced vascular permeability assay methods. Heat and hypotonicity-induced heamolysis of human red blood cell membrane were also used to assess its membrane stabilizing effect and to determine its inhibitory property on phospholipase A2 activity....

Author(s): Odu Nwamaka Maureen, Tchimene Kenne Michel, Ogugua Victor Nwadiogu, ObongaWilfred, Sunday Patrick Gaza Anze and Nwanguma Bennett Chima  

September 2018

Genotoxic effects of Peganum harmala L. in relation to traditional use

Peganum harmala L. is a well-known medicinal plant, widely distributed and used in folk medicine. Recently, numerous reports have been published regarding the pharmacological and therapeutic effects of P. harmala and its major alkaloids components. However, mammalian toxicity due to P. harmala alkaloids extract has been rarely investigated. The present research aimed to study the genotoxic effects of harmala plant...

Author(s): Salim M. Abderrahman, Sameh Soliman and Mohammad G. Mohammad  

September 2018

In vitro anticancer screening of Colombian plants from Piper genus (Piperaceae)

Historically, knowledge of ethnobotany, which has revealed different phytochemical and pharmacological compounds from traditional plants, has formed the basis for new anticancer drug discovery. The use of some Piper species in traditional medicine against cancer, suggests that genus Piper is a promising source of new compounds with anticancer activity. A total of 28 ethanolic extracts were obtained from 16 different...

Author(s): Diego R. Muñoz, Adrián G. Sandoval-Hernandez, Wilman A. Delgado, Gonzalo H. Arboleda and Luis E. Cuca  

August 2018

Evaluation of the therapeutic and toxicological knowledge of herbalists on the most notified plants in the poison control and pharmacovigilance center of Morocco

According to the World Health Organization, 80% of the population in developing countries is engaged in traditional medicine. Consequently, the issue of poisoning by plants is not negligible. The objective of this study is to evaluatethe therapeutic and toxicological knowledge of herbalists of the most reported plants in the anti-poison center of Morocco. Field study by direct interview with 20 herbalists of the...

Author(s): Imane Zakariya, Jihane Ifezouane, Amal Addaoui, Souad Skalli and Yassir Bouslimane

August 2018

The Mexican mistletoe Struthanthus venetus (HBK Blume) inhibits proliferation and synergizes antagonistic actions of Tamoxifen and Fulvestrant in breast cancer MCF-7 cells

Mistletoes are hemi-parasitic plants widely distributed around the world, used in folk medicine to treat many diseases including diabetes, hypertension, menopausal syndrome and as complementary or adjuvant treatment for cancer. The objective of the present work was the evaluation of oestrogenic activity of hydromethanolic extract of mistletoe Struthanthus venetus dried leaves (StvHME), to evaluate its potential benefits...

Author(s): Marte Lorenzana-Jiménez, María Estela Avila, Alejandra Figueroa, Lorena Mendiola-Almaraz, Gil Alfonso Magos Guerrero and Cristina Lemini  

August 2018

Protective effect of ethanolic extract of Cucurbita maxima (PUMPKIN) leaf on acetaminophen-induced acute liver toxicity

Ethanolic extract of dried leaves of Cucurbita maxima (Pumpkin) were screened for their phytochemical composition. The in vitro antioxidant property was determined by assessing the free radical (DPPH) scavenging activity. Twenty rats divided into four groups were used for this study with group 4 pre-treated with the extract and later intoxicated with 2 g/kg single dose of acetaminophen. The hepatoprotective effect of...

Author(s): Michael Okey Enemali, Titilayo Oluwayemisi Bamidele and Mohammed Abdullahi Ubana

July 2018

Pulcandi a healing natural ash coal against gastric acidity: Scientific comprehension

As a coal, Pulcandi possesses the property of removing excess gastric and intestinal gas. Pulcandi powder has anti-diarrhea activity by decreasing intestinal fluid content and adsorbing microbes and toxins. The aim of this study was to demonstrate and to establish consequences of Pulcandi powder use on gastric acidity. For evaluating these consequences, it was investigated in vitro kinetic tests on acidity. These tests...

Author(s): Akpalo Edéfia, Aba Eklu Gudrun, Awaga  Kwami Lumo and Aba Eklu Abatévi

July 2018

Comparative evaluation of the protective effect of leaf extracts of Vernonia amygdalina (bitter leaf) and Ocimum canum (curry) on acetaminophen induced acute liver toxicity

The quest for alternate medicine in preventing and combating hepatotoxicity led to the screening of aqueous and ethanol extracts of dried leaves of Vernonia amygdalina Delile (bitter leaf) and Ocimum canum Linn (curry leaf) for phytochemicals and in vitro antioxidant properties. Some rats were pretreated with the extracts and later administered with 2g/kg of body weight single dose of acetaminophen and the...

Author(s): Michael Okey Enemali and Stanley Chidi Udedi  

June 2018

Fungal metagenomes in polyherbal medicines used for the treatment of tuberculosis

The traditional systems of medicine have significantly become more accepted in the developed and developing countries due to their curative property, less toxicity and minimal side effects. However, several studies have shown that they are associated with microbial contaminants. This study aimed at identifying fungi in nine polyherbal medicines used for the treatment of tuberculosis in Eastern Cape Province, South...

Author(s): Elizabeth Bosede Famewo, Anna Maria Clarke and Anthony Jide Afolayan

May 2018

Ethnopharmacological studies of plants used for the treatment of rheumatic affections in Ouagadougou, Burkina Faso

Plants are a considerable source of active substances which are exploited in the treatment of several diseases, among which are rheumatic affections. This study aimed to explore the knowledge of traditional practitioners and patients on medicinal plant species of Ouagadougou, Burkina Faso, used for the treatment of rheumatic affections. Direct interviews with open-ended and closed-ended questionnaires were used to...

Author(s): Estelle Noëla Hoho Youl, Joëlle W. Stephanie Tiendrebeogo, Fasteylah Y. Hounlidji, Frank Edgard R. Zongo, Aminata Nacoulma, Innocent Pierre Guissou and  Dieu-Donné Ouedraogo  

April 2018

Pharmacognostic evaluation of the leaf of Microtrichia perotitii DC. (Asteraceae)

Microtrichia perotitii DC. belongs to the family Asteraceae (Compositeae) and it is a herb found in the West African countries. The aim of this research was to establish pharmacognostic standards for M. perotitii through macroscopic, microscopic, chemo-microscopic and physico-chemical investigations. The macroscopic studies revealed the shape of the leaf as small with acute apex, asymmetric base, pubescent surface with...

Author(s): Abdullahi, M. N., Ilyas, N., Hajara, I. and Kabir, Y. M.  

April 2018

Effect of Ethiopian high land green tea (Camellia sinensis) leaf extract on highly active anti-retroviral therapy induced dyslipidemia in Albino Wistar rats

Highly active antiretroviral therapy (HAART) is considered toxic and has other life-threatening side effects including dyslipidemia. There is no research report on the health effects of Ethiopian highland green tea. Previous work data from elsewhere suggest that lipid abnormalities are associated with cardiovascular morbidity and mortality. The aim of this study was to investigate the possible protective effect of green...

Author(s): Tesaka Wondimnew, Natesan Gnanasekaran and Solomon Genet  

March 2018

Antimicrobial activities from extracts of seven medicinal plant species against multidrug-resistant bacteria and fungi

This is the first to report the antimicrobial effects of extracts of seven endemic medicinal plants. Flower extracts of Onopordum jordanicolum exhibited antibacterial activity against Staphylococcus aureus, MRSA, Klebsiella pneumonia, and Proteus mirabillis. Ethanol extract displayed significant antibacterial activity against S. aureus with the best MIC and MMC values. Onopordum blancheanum flower extracts produced...

Author(s): Maher Obeidat

March 2018

The impact of seasonal variation on the volatile oil profile of leaves of Severinia buxifolia (Poir.) and its antimicrobial activity

The effect of the time of collection on the quality and quantity of the oil obtained from Severinia buxifolia leaves as well as its antimicrobial activity was studied. The chemical composition of the hydro-distilled oils of the leaves of S. buxifolia (Poir.)Tenore, collected at the four seasons was determined by GC/MS analysis. Moreover, antimicrobial activity was studied, for the oil sample regarding the yield and...

Author(s): Safaa A. Nour, Mostafa A. Abdel Kawy, Maha M. Salama, and Mohamed S. Hifnawy  

March 2018

Ethnobotanical study of medicinal plants used to treat human ailment in Guduru District of Oromia Regional State, Ethiopia

This research was carried out to document ethnobotanical data and threats affecting medicinal plants. Semi-structured interviews, questionnaires, face to face discussion, and field visit was employed to gather the required data. A total of 92 informants 21 key and 71 randomly selected informants), of which 48 males and 44 females were used. The study documented 57 plants species which belongs to 55 genera and 41...

Author(s): Abiyot Tadesse, Birhanu Kagnew and Firew Kebede  

February 2018

Anticancer activities and safety evaluation of selected Kenyan plant extracts against breast cancer cell lines

Breast cancer is a leading cause of deaths among women suffering from cancer in Kenya. The current study was done to determine anticancer activities of medicinal plant extracts against breast cancer cell lines (HCC 1395 and 4T1). Vero cells were used for evaluation of safety of extracts. Thiazoly blue tetrazolium bromide (MTT) assay was used in this study. Reference drugs were 5 fluorouracil and cyclophosphamide....

Author(s): Onyancha Jared M., Gikonyo Nicholas K., Wachira Sabina W., Mwitari Peter G. and Gicheru Michael M.

February 2018

Pharmacognosy and phytochemical standardization of Albizia Ferruginea (Guill and Perr) pulps

In Africa and Cameroon in particular, people tend to use medicinal plants as the first approach to cure their illness or disease. In order to improve the safety and the progressive integration of those plants in our health systems, it is important to set a system and protocol that would permit an easy characterization, quality and safety control of medicinal plants through a standardization of their recipes. Thus, we...

Author(s): Rose Ngono Mballa Abondo, Aude P´erine Minyem Ngombi, Joseph Ngoupayo, Bonaventure Ngadjui Tchaleu and Beyeme Fridoline-Victorine

February 2018

Diterpenes of the pimarane type isolated from Viguiera arenaria: Promising in vitro biological potential as therapeutic agents for endodontics

Viguiera arenaria, family Asteraceae, is a plant that contains diterpenoids, which make this species potentially applicable in endodontics. More specifically, V. arenaria contains diterpenes of the pimarane type, which display various classic biological activities. This study evaluates the antibiofilm activity, the time-kill curve, and the inhibitory concentration index of diterpenes of the pimarane type...

Author(s): Soraia Marangoni, Thais da S. Moraes, Susane H. Utrera, Luciana A. Casemiro, Maria G. M. de Souza, Pollyanna F. de Oliveira, Rodrigo C. S. Veneziani, Sérgio R. Ambrósio, Denise C. Tavares and Carlos H. G. Martins

January 2018

Amelioration potentials of Vernonia calvaona ethanol leaf extract in paracetamol-treated rats

Paracetamol toxicity due to overdose amongst people living in the developing countries has been on the increase. This study investigated the amelioration potentials of Vernonia calvaona ethanol leaf extract in paracetamol-treated rats. Thirty five Wistar rats were divided into five groups of seven rats each. Hepatic damage was induced by administering 2 g/kg b.wt of paracetamol p.o for four day to all the groups except...

Author(s): Eyong Ubana Eyong, Godwin Eneji Egbung and Victor Ndubuisi Ndiodimma

January 2018

Chemical composition and in vitro investigation of biological activities of Hemizygia bracteosa (Benth.) Briq leaves

Hemizygia bracteosa (Benth.) Briq (Lamiaceae) is used in the treatment of mental disease, memory loss, HIV, malaria and had antimicrobial and hypoglycemic properties. To the authors’ knowledge, no scientific study has been done on these properties except antimicrobial and hypoglycemic properties. The phytochemical investigation focused on the quantification of phenolic compounds, flavonoids, tannins, anthocyanins...

Author(s): Marthe Dominique Chodaton Zinsou, Fidèle M. Assogba, Fernand Gbaguidi and Mansourou Moudachirou

December 2017

Phytochemical and biological analyses of Citharexylum spinosum

The phytochemical screening of Citharexylum spinosum L. aerial parts resulted in the presence of flavonoids, tannins, carbohydrates and/or glycosides, triterpenes and/or sterols and saponins. The percentage of hydrocarbons and sterols in C. spinosum petroleum ether extract were 99.57 and 0.3%, respectively. In petroleum ether extract, saturated fatty acids (78.76%) and unsaturated fatty acids (9.14%) were found....

Author(s): Amel M. Kamal, Mohamed I. S. Abdelhady#, Heba Tawfeek#, Maha G. Haggag# and Eman G. Haggag#

December 2017

Phytochemical analysis, antioxidant and antimicrobial activities of leaves and flowers ethyl acetate and n-butanol fractions from an Algerian endemic plant Calycotome spinosa (L.) Link

Calycotome spinosa (L.) Link is one of the important plants in traditional medicine especially in Algeria. The present work deals with the phytochemical screening, the flavonoids extraction from leaves and flowers of this plant, the quantification of total polyphenols and flavonoids, as well as the evaluation of antioxidant and antimicrobial properties of ethyl acetate and n-butanol fractions. While, the rest,...

Author(s): Radia Cherfia, Mounira Kara Ali, Imen Talhi, Akila Benaissa and Noreddine Kacem Chaouche

November 2017

Evaluation of some biological activities of Trigonella hamosa aerial parts

The antimicrobial activity of T. hamosa aerial parts extract against Bacillus subtilis, Staphylococcus aureus, Enterococcus fecalis, Escherichia coli, Pseudomonas auregenosa, Candida albicans, Fusarium sp. and Aspergilus niger was evaluated by disc diffusion method. The minimum inhibitory concentrations (MICs) for susceptible test microorganisms were further determined. Also the antioxidant and α-amylase...

Author(s): Sameer H. Qari and Nayer M. Fahmy

October 2017

Ethnobotanical survey of plants used in the management of mental illnesses in some selected local government areas of Plateau State, Nigeria

Mental illness refers to all diagnosable mental disorders which are characterised by abnormalities in thinking, feelings or behaviours. Ethnobotanical study surveyed the different types of medicinal plants used for the treatment of mental illness in Bassa, Pankshin, and Kanke Local Government Areas of Plateau State, Nigeria. Information was obtained from traditional medicine practitioners, herbalist and herb sellers,...

Author(s): Ior L. D., Otimenyin S. O., Okwori V. A., Umar D. M. and Azila J. J.

October 2017

Pharmacognostic evaluation of the leaves and roots of Cassia sieberiana DC.

Cassia sieberiana DC. (Leguminosae - Caesalpinioideae), commonly known as drumstick and ‘aridantooro’ in Yoruba, is a perennial tree native to Africa. It is used in ethno-medicine to manage arthritis and rheumatism. Pharmacological activities such as myorelaxant, antispasmodic, anti-inflammatory, and antimicrobial have been reported in literature. Pharmacognostic investigation including microscopy,...

Author(s): Fatokun Omolola T., Esievo Kevwe B., Ibrahim Jemilat A. and Kunle Oluyemisi F.

September 2017

Antioxidant potential and cytotoxicity of Randia dumetorum Lam. leaf extract

The aim of the current study was to explore the antioxidant potential and cytotoxicity of different ’fractions from the leaf extract of Randia dumetorum. Proximate analysis and phytochemical screening were done with standard protocol. The antioxidant activity was evaluated by using reducing power assay, total antioxidant capacity determination, determination of total phenolic content, determination of total...

Author(s): Abdullah-Al-Ragib, Md. Tanvir Hossain, Javed Hossain and Md. Jakaria,

August 2017

Phytochemical and zootechnical studies of Physalis peruviana L. leaves exposured to streptozotocin-induced diabetic rats

This is a phytochemical and zootechnical study on Physalis peruviana leaves in streptozotocin induced diabetic rats. This was part of a scientific development program of plant resources used in Congolese traditional medicine for the treatment of diabetes mellitus in which individual and community consequences are well established. Different fractions with hexane, ethyl acetate and the residue were obtained from the...

Author(s): C. N. Fokunang, F. K. Mushagalusa, E. Tembe-Fokunang, J. Ngoupayo, B. Ngameni, L. N. Njinkio, J. N. Kadima, F. A. Kechia, B. Atogho-Tiedeu, W. F. Mbacham and B. T. Ngadjui

August 2017

Pharmacognostic studies and elemental analysis of Cassytha filiformis Linn

Cassytha filiformis, a leafless and perennial vine with small scales as a replacement of the leaves is currently being used in the treatment of various disease conditions such as jaundice. Macroscopic/ organoleptic characters, microscopic, chemo-microscopic characters, numerical standards, and elemental analysis were determined from the whole plant of C. filiformis. Findings from this study revealed the presence of some...

Author(s): Adamu A. Ambi, Garba F. Nuru, Ahmed T. Mora and Abubakar Ahmad

July 2017

Potential health benefits and scientific review of ginger

Ginger has been known for its several scientific properties and valued for the last 2500 years in different parts of the globe. Ginger has rich phytochemistry and several health promoting perspectives. In ginger family, Zingiber officinalis is one of most widely used species and it is found in several foods and beverages. Ginger has been used commonly to treat diarrhea, stomach upset, indigestion and nausea. It also has...

Author(s): Najim A. Jabir Al-Awwadi

July 2017

Assessment of the effect of aqueous leaf extract of cassava (Mannihot esculenta) on adult Wistar rats

This study aimed to explore the effect of aqueous leaf extract of Mannihot esculenta on the morphology and histology of the kidney of adult Wistar rats. Three groups of Wistar rats were used. Group A served as the control treated with 0.3 ml of normal saline, while groups B and C served as the experimental groups. Group B and C were treated with aqueous extract of M. esculenta orally at 0.2 and 0.5 ml, respectively for...

Author(s): Kebe E. Obeten, Imasa E. Ushie, Gabriel Udoaffah and Obi O. Ndifon

June 2017

In vivo anti-plasmodial activity and histopathological analysis of water and ethanol extracts of a polyherbal antimalarial recipe

Anthocleista djalonensis A. Chev. (stem bark), Azadirachta indica A. Juss (stem bark and leaf), Cajanus cajan (L.) Huth. (leaf), Crescentia cujete L. (stem bark), Lawsonia inermis L. (leaf), Lophira alata Banks ex C.F. Gaertn. (stem bark), Myrianthus pruessii Engl. (leaf), Nauclea latifolia Sm. (stem bark), Olax subscorpioidea Oliv. (root), and Terminalia glaucescens Planch ex Benth. (stem bark and root) are combined...

Author(s): Mojirayo Rebecca Ibukunoluwa

June 2017

Ethnopharmacological survey of plants used for the treatment of diabetes in the town of Sidi Slimane (Morocco)

The study aimed to screen the antidiabetic plants used by 700 diabetic patients in the town of Sidi Slimane (northwestern Morocco). The results identified 59 species belonging to 28 botanical families, four of which are predominant (Lamiaceae: 9 species; Apiaceae: 7 species; Asteraceae: 5 species; Fabaceae: 4 species). The most used species are: Trigonella foenum-graecum, Oreganum vulgare, Salvia officinalis, Marrubium...

Author(s): M. Laadim, M. L. Ouahidi, L. Zidane, A. El Hessni, A. Ouichou and A. Mesfioui

May 2017

Phytochemical and biological investigation of Eugenia uniflora L. cultivated in Egypt

Eugenia uniflora L. (Myrtaceae) is a plant species used in folk medicine for treatment of various disorders. This study aims to quantify the phenolic and flavonoid contents of E. uniflora aqueous methanolic extract (AME), identification of its major constituents, as well as the evaluation of its biological activity. Quantification was performed using colorimetric assays. Column chromatographic separation was used for...

Author(s): Riham O. Bakr, Shaza A. Mohamed and Nermien E. Waly

May 2017

Chemical constituents and biological activities of different solvent extracts of Prosopis farcta growing in Egypt

Different solvent extracts from the aerial part of Prosopis farcta growing in Egypt have been biologically evaluated by studying their antimicrobial, anticancer and antioxidant activities. Furthermore, the chemical analysis using GC/MS has been performed for the promising extracts n-hexane and methylene chloride, and this analysis led to the identification of twenty six and thirty two compounds respectively from...

Author(s): Amal Mohamed Saad, Mosad Ahmed Ghareeb, Mohamed Sayed Abdel-Aziz, Hassan Mohamed Fawzy Madkour, Omar Maajal Khalaf, Ahmed Kamel El-Ziaty and Mamdouh Abdel-Mogib

April 2017

Mystroxylon aethiopicum chloroform root bark extracts phytochemical analysis using gas chromatography mass spectrometry

Mystroxylon aethiopicum has been used by many ethnic groups in Africa for the management of hemorrhagic diarrhea, stomachache, respiratory tract infections, urinary tract infections coughs, hypertension and gonorrhea. This study was carried out to identify low molecular weight phytochemicals present in the root bark extract of M. aethiopicum with the aid of gas chromatography-mass spectrometry (GC-MS) technique. The...

Author(s): Mhuji Kilonzo, Patrick A. Ndakidemi and Musa Chacha

April 2017

Anti-asthma potential of dried Draco Spilopterus Wieg. 1834 (Philippine Flying Dragon) using mesenteric mast cell count by atopic allergy method

Decocted Draco spilopterus has been utilized in the Philippines for the treatment of asthma associated with its strong folkloric beliefs however no scientific evidence was available to prove such claims. Thus, the researchers ventured into this study to determine the anti - asthma potential of dried D. spilopterus on male albino rats using mesenteric mast cell count by atopic allergy method. Fifteen D. spilopterus were...

Author(s): Gerard Lee L. See, Aj Et War Yazsine A. Ocampos, Nicole Angelli Y. Yap and Florencio V. Arce, Jr.

March 2017

Biochemical and antioxidants activity of crude, methanol and n-hexane fractions of Vernonia calvoana on streptozotocin induced diabetic rats

This study is aimed at evaluating the biochemical effects and antioxidants activity of extracts of Vernoia calvoana Hook. f (V.C) on STZ induced diabetic rats. Thirty-six rats weighing (100 to 150 g), were divided into 6 groups of 6 animals each. Groups 1 and 2 representing normal and diabetic controls (NC and DC), respectively, receiving placebo, while groups 3 to 6 represented diabetic treated, receiving 500 mg/kg...

Author(s): Iwara Arikpo Iwara, Godwin Oju Igile, Friday Effiong Uboh, Kelvin Ngwu Elot and Mbeh Ubana Eteng

March 2017

Phytochemical profile of stem bark extracts of Khaya senegalensis by Gas Chromatography-Mass Spectrometry (GC-MS) analysis

The phytochemical constituents of stem bark extracts of Khaya senegalensis were isolated and analyzed using Gas Chromatography-Mass Spectrometry (GC-MS). A shade-dried stem bark of K. senegalensis was extracted using methanol and water as solvents. The main chemical compositions of the extracts were analyzed by GC-MS and preliminary phytochemical analysis was performed to confirm the various classes of active chemical....

Author(s): Celestine Uzoma Aguoru, Christopher Gbokaiji Bashayi and Innocent Okonkwo Ogbonna

February 2017

Antioxidant and hepatoprotective effect of Urtica Dioica extract against N-nitroso methyl urea induced injuries in mice

The aim of this study is to investigate the antioxidant and protective effect of an aqueous extract from Urtica dioica on liver injuries, induced by one of the most potent dietary carcinogenic agents N- Nitroso methyl urea (NMU). Firstly, the free radical scavenging activity of U. dioica extract was assessed by measuring its capability to scavenge the radical 2,2-diphenyl-1-picrylhydrazyl (DPPH). Liver injury was...

Author(s): El Ouar Ibtissem, Tartouga Maya Abir , Loucif Oumayma Rokeya and Naimi Dalila,

January 2017

Chemical composition and anticancer activity of Achillea fragrantissima (Forssk.) Sch. Bip. (Asteraceae) essential oil from Egypt

The aerial parts of Achillea fragrantissima (Forssk.) Sch. Bip., wildly grown in Egypt, yielded 0.8 and 1.5% (v/w) of essential oils prepared by hydrodistillation (HD), or by conventional volatile solvent extraction method (preparation of the “absolute”, SE), respectively.  The volatile components of this essential oil were determined by GC–MS analyses. Twenty eight compounds were identified in...

Author(s): Mouchira Aly Choucry

January 2017

Antibacterial and antifungal activities of leaf extracts of Phyllanthus amaru Schum and Thonn.

The leaf extracts of Phyllanthus amarus Schum and Thonn. a common Western Nigerian weed, was investigated for phytochemical constituents and antimicrobial activities. Hexane extracts demonstrated the highest extraction of 59% followed by Acetone (57%) and water (48%). Saponins, tannins, alkaloid flavonoids, balsam, anthraquinones and phenols were extracted in an acidic medium. Twelve microorganisms (8 bacterial species...

Author(s): Senjobi, C.T., Ettu, A. O. and Otujo, C.O.

January 2017

Brown seaweeds administration generate psychotherapeutic response associated with brain norepinephrine modulation in rats

Research in the area of herbal psychopharmacology has increased considerably over the past few decades in search of panacea for neuroprotection. Seaweeds are one of the herbal sources consumed in many Asian countries as medicine due to their remarkable bioprospecting properties and evident health benefits. Keeping in view the bioactive potential of seaweeds, the present study was designed to evaluate the...

Author(s): Adnan Khan, Nizam Uddin, Saima Khaliq, Shazia Nawaz, Munawwer Rasheed, Ahsana Dar, Muhammad Hanif and Pirzada Jamal Ahmed Siddiqui

December 2016

Phytochemical and antioxidant studies of methanol and chloroform extract from leaves of Azadirachta indica A. Juss. in Tropical region of Nepal

This research was carried out with the aim of phytochemical analysis and determining antioxidant activity present in methanol and chloroform leaf extracts of Azadirachta indica. Due to its potential in curing various ailments as well as wide spread application of antioxidant activity such as in the field of cosmetology, the plant was selected for the study. The total phenolics contained in the plant extracts were also...

Author(s): Dhakal S., Aryal P., Aryal S., Bashyal D. and Khadka D.

December 2016

Preliminary bioactivity investigation of Styrax officinalis fruit extract as potential biopesticide

Styrax officinalis is a deciduous large shrub that grows in many Mediterranean countries. Active ingredients are localized in the fruit pericarp. Primary phytochemical analysis showed the presence of saponins, tannins and triterpenes and absence of alkaloids and flavonoids. No antimicrobial, but strong ichthyotoxic and molluscicidal effects were observed in the saponin-rich extract .Toxicity tests with the snail Cornu...

Author(s): Robert Dib, Karim Makhoul and Rita Maalouf

November 2016

Antioxidant, hypolipidemic and preventive effect of Hawthorn (Crataegus oxyacantha) on alcoholic liver damage in rats

The use of alcoholic beverages is more common and accepted by our society despite the health risks. Alcohol catabolism produces free radicals that cause oxidative stress and damage in liver principally. Hawthorn (Crataegus oxyacantha) is a medicinal plant that has been shown to have wide variety of polyphenolic compounds with antioxidant and hypolipidemic effect. The objective of this study was the evaluation of...

Author(s): José Luis Martínez-Rodríguez, Claudia Araceli Reyes-Estrada, Rosalinda Gutiérrez-Hernández and Jesús Adrián López

October 2016

Amaranthus viridis modulates anti-hyperglycemic pathways in hemi-diaphragm and improves glycogenesis liver function in rats

Amaranthus viridis is an ecumenical species in the botanical family of Amaranthaceae, which has been traditionally used to treat several skin diseases along with some antilipidemic activities. The present study was carried out to investigate the anti-hyperglycemic effect of 75% ethanolic extract of A. viridis in Neonatal streptozotocin (N-STZ) induced rats’ hemi-diaphragm, including screening for secondary plant...

Author(s): Shihab Uddin, Md. Mahmodul Islam, Md. Mynul Hassan, Amrita Bhowmik and Begum Rokeya

October 2016

Evaluation of antioxidant and anti-tyrosinase activities as well as stability of green and roasted coffee bean extracts from Coffea arabica and Coffea canephora grown in Thailand

Coffea arabica (Arabica) and Coffea canephora (Robusta) are the economic plants in Thailand that are widely cultivated in Northern and Southern Thailand. This study aims to evaluate the antioxidant, anti-tyrosinase activities, toxicity, stability and identify chemical components of the coffee bean extracts. The best extract that showed good biological activities will be further used to develop cosmeceutical products....

Author(s): Kanokwan Kiattisin, Thananya Nantarat and Pimporn Leelapornpisid

September 2016

Effect of seasonal changes on the quantity of phytochemicals in the leaves of three medicinal plants from Limpopo province, South Africa

The study was carried out to investigate the effect of seasonal changes on the quantity of phytochemicals in leaves of three medicinal plants: Barleria dinteri, Grewia flava and Jatropha lagarinthoides, collected from Limpopo province in South Africa. Three medicinal plants were collected during different seasons of the year and phytochemicals were quantified on plant samples collected in each season. Alkaloids and...

Author(s): S. S. Gololo, L. J. Shai, N. M. Agyei and M. A. Mogale

August 2016

Comparative study between effects of ethanol extract of Zingiber officinale and Atorvastatine on lipid profile in rats

Zingiber officinale is known for its cholesterol-lowering and antioxidant properties. The use of traditional medicine reduces the use of drugs with a risk of toxicity. This study aims to assess the effects of ethanol extract of Z. officinale and atorvastatin on lipid parameters in rats fed with high-fat diet. The experiment was carried out on 40 rats during 9 weeks. The animals were divided into 4 groups; group 1...

Author(s): Abdelkrim Berroukche, Abdelkrim Attaoui and Mustafa Loth

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