Journal of
Medicinal Plants Research

  • Abbreviation: J. Med. Plants Res.
  • Language: English
  • ISSN: 1996-0875
  • DOI: 10.5897/JMPR
  • Start Year: 2007
  • Published Articles: 3654

JMPR Articles

September 2016

Anti-candida biofilm properties of Cameroonian plant extracts

Candida infections can be superficial, invasive or disseminating. The virulence of Candida species has been attributed to several factors, including the promotion of hyphae and biofilm formation, adherence to host tissues, and response to environmental changes and morphogenesis. Resistance to many clinically used antifungal agents has led to the need to identify new compounds and drugs for therapeutic use. Therefore,...

Author(s): Zeuko´o M. Elisabeth, Virginio C. Lopez, Sara M. Soto and Fekam B. Fabrice

September 2016

Antimicrobial activities and preliminary phytochemical tests of crude extracts of important ethnopharmacological plants from Brazilian Cerrado

Screening of native plants with therapeutical effects constitutes a valuable way to enhance biological attributes of medicinal herbs and discover new drugs. Therefore, ethanol and methanol extracts from ten plants collected from Brazilian Cerrado were tested to inhibitory effects against Escherichia coli (ATCC 25922), Staphylococcus aureus (ATCC 25923) and Pseudomonas aeruginosa (ATCC 27853) through disc diffusion. The...

Author(s): Caroline N. Maia, Cláudia M. da Silva, Ronaldo R. Júnior, Dario A. Oliveira, Perácio R. B. Ferreira, Carla Soares Godinho, Elio G. Fernandes and Henrique M. Valério

September 2016

Anti-HIV-1 activity in human primary cells and Anti-HIV-1 RT inhibitory activity of extracts from the red seaweed Acanthophora spicifera

First generation drugs such as zidovudine have been extensively used in clinical practice, resulting in the development of HIV resistance to these nucleoside analogs. Several studies have demonstrated the effective anti-HIV activity of natural products derived from seaweeds, suggesting promising sources of substances for the development of novel antiviral drugs. In this paper, the antiviral effect of extracts from the...

Author(s): Caio Cesar Richter Nogueira, Izabel Christina Nunes de Palmer Paixão, Claudio Cesar Cirne-Santos, Paulo Roberto Soares Stephens, Roberto Campos Villaça, Helena de Souza Pereira and Valéria Laneuville Teixeira

September 2016

Aqueous extract of Bowdichia virgilioides stem bark inhibition of allergic inflammation in mice

This study evaluated the anti-allergenic properties of the aqueous extract of the stem bark from Bowdichia virgilioides (AEBv). Oral administration of AEBv inhibited the plasma protein leakage at 30 min post allergenic challenge in Swiss mice actively sensitized with ovalbumin (OVA). AEBv inhibited OVA-induced histamine release in vitro in tissues obtained from sensitized mice. AEBv-treated mice exhibited a lower influx...

Author(s): Juliane Pereira da Silva, Jamylle Nunes de Souza Ferro, Benisio Ferreira da Silva Filho, Luiz Antônio Ferreira da Silva, Tayhana Priscila Medeiros Souza, Heloisa de Carvalho Matos, Vinicius de Frias Carvalho, Renato Santos Rodarte and Emiliano Barreto

September 2016

Sensitization with babassu mesocarp induces activation of murine splenocytes against tumor cells

Attallea speciosa Mart. (babassu) fruit contains a mesocarp that is rich in carbohydrates with immunomodulatory effects. The induction of the tolerogenic response is a tumor escape mechanism, and immunomodulator adjuvants have been studied to reestablish host immunogenicity. This study evaluates the adjuvant potential of babassu mesocarp carbohydrates in a tumor model. The babassu mesocarp extraction (BME) yield was...

Author(s): Leticia Prince P. Pontes, Josemar M. F. Godinho Jr., Elza Moraes, Diego S. Arruda, Caroline S. C. Almeida, Mayara C. Pinto, Graciomar C. Costa, Rosane N. M. Guerra, Luce M. B. Torres, Vanessa F. Oliveira, Flávia R. F. Nascimento and Ana P. S. Azevedo-Santos

September 2016

Curcuma comosa ameliorates cisplatin-induced nephrotoxicity: COX-2 expression and ultrastructure changes

To determine the protective effects of ethanol extracts of Curcuma comosa on kidney injury by cisplatin, mice were randomly assigned into 4 groups: Control, cisplatin control (12.5 mg/kg body weight (BW), i.p.), C. comosa+cisplatin (pretreatment with C. comosa at dose 200 mg/kg BW orally for 4 consecutive days before cisplatin injection), and C. comosa control groups. After five days, the renal tissues were collected to...

Author(s): Alan Chuncharunee, Valainipa Habuddha and Aporn Chuncharunee

September 2016

Chemical Composition antimicrobial and free radical scavenging activity of essential oil from leaves of Renealmia thyrsoidea (Ruiz &Pav.) Poepp. & Endl.

Renealmia thryrsoidea  (Ruiz & Pav.)  Poepp. & Endl is a plant used by the Amazonian indigenous people of Ecuador for its various medicinal properties. Its leaves exhibit a remarkable aroma with a hint of spiciness. The essential oil extracted from its leaves was analyzed by GM/MS, using two systems with columns of different polarity, in both was confirmed  the presence of terpinolene (26.32%),...

Author(s): Paco F. Noriega, Erika A. Paredes, Tatiana D. Mosquera, Edison E. Díaz, Angelika Lueckhoff, Jessica E. Basantes and Andrea L. Trujillo

September 2016

Bioactivity of Platycerium angolense Flavonoid Fraction on Biochemical Parameters of Acetaminophen-induced Rats

This study evaluated the effect of flavonoid fraction (FF) of Platycerium angolense on acetaminophen-induced liver damage in rat with a view to considering the possibility of utilizing the extracts of the plant for the management and treatment of liver related ailments. Powdered leaves of P. angolense were extracted with methanol 70% (v/v) to yield methanolic extract of P. angolense (MEPA). The MEPA followed successive...

Author(s): Akinlalu, Akintunde Oluseto, Komolafe, Ige Joseph, Ogunsusi Mayowa and Oyedapo, Oluboade Oluokun

September 2016

Distribution of phenolic content and screening for antioxidant capacity of different parts of tea plant (Camellia sinensis L.)

Tea is a medicinal beverage manufactured from the plant, Camellia sinensis L. The bud and two adjacent leaves (tea flush) are generally harvested in this process. Currently, it is also used as an ingredient in cosmetic products. The present study was carried out to screen the antioxidant activity and the distribution of phenolic content in different parts of the tea plant for their utilization in other industries....

Author(s): Piumi Dasanayake, and Preethi Soysa

August 2016

Impact of Colombian yellow fruits and tropical fruits drinks consumption on the antioxidant status of healthy women

Reactive oxygen species are responsible for causing different types of damage in the body which are associated with the onset of chronic non-communicable diseases. A strategy to counteract these effects is by a diet rich in antioxidants compounds found in fruits. The aim of this study was to determine the antioxidant capacity in plasma and the content of total phenolic compounds in healthy women who consumed a drink...

Author(s): Ana Cristina Gómez-García, Jeanine Peñaloza, Julio Cañas, Benjamín Rojano, Ana Rosa Ramos and Maria Elena Maldonado

August 2016

Effects of extraction solvents of dietary plants on lipid lowering activity

The present study aims to investigate the effects of five dietary plants including Azadirachta indica A. Juss. var. siamensis Valeton (flowers), Bombax ceiba Linn (pollen), Citrus hystrix DC (leaves), Polygonum odoratum Lour (leaves), and Solanum torvum Sw (fruits) on activity of pancreatic lipase, micellar cholesterol solubilization and bile acids binding. Two different organic solvents (methanol and ethanol) and...

Author(s): Acharaporn Duangjai, Nanteetip Limpeanchob, Kanittaporn Trisat and Anan Ounaroon

August 2016

Antibacterial, antifungal and in vitro cytotoxic activities of three extracts isolated from mint

A number of reports have been focusing on chemical compositions and functional properties of essential oils isolated from mint. However, there is little data available on the biological activities of non-volatile constituents. In this study, the antibacterial (against 2 gram-positive bacterial strains: Staphylococcus aureus and Bacillus cereus; 2 gram-negative bacterial strains: Escherichia coli and Pseudomonas...

Author(s): Dongbo Liu,, Liqin Hu, Xuehui Liu, Xincong Kang, Yongquan Hu, Hongqi Xie, Zhilan Xia and Ling Xie

August 2016

Versatility and consensus of the use of medicinal plants in an area of cerrado in the Chapada do Araripe, Barbalha - CE- Brazil

This study aimed to conduct an ethnobotanical survey of medicinal species in an área of cerrado vegetation in the chapada do Araripe, Ceara, as well as evaluating and selecting species with potential for bioprospecting, based on the relative importance of the species and the consensus among the informants. The ethnobotanical data were collected through semi-structured interviews and a free list, and by using the...

Author(s): Delmacia G. Macêdo, Irwin R. A. Menezes, Sirleis R. Lacerda, Maria A. P. da Silva, Daiany A. Ribeiro, Maria S. Macêdo, Liana G. S. Oliveira, Manuele E. Saraiva, Sarah R. Alencar, Samara F. Oliveira,  Maria O. Santos, Bianca V. de Almeida, Julimery G. F. Macedo, Francisca F. S. Sousa, Marília A. Soares, Thatiane M. S. de Araújo and Marta M. A. Souza

August 2016

Investigation of the inhibitory effects from the Brazilian medicinal plant Pothomorphe umbellata L. (Piperaceae) on the molecular pathways of cyclooxygenase-2 and nuclear factor kappa B

Presently, medicinal plants, such as Pothomorphe umbellata L. (Piperaceae), have been assessed as sources of potential therapeutic medicines. The inhibitory effects of the crude extract, fractions and 4-nerolidylcathecol, a phenolic compound which has been assigned significant activity in several beneficial properties performed by the plant, on the molecular pathways of cyclooxygenase-2 (COX-2) and nuclear factor kappa...

Author(s): Andrey Pereira Lopes, Bianca Souza Bagatela, Fernando Luiz Affonso Fonseca, Edson Luis Maistro, Jairo Kenupp Bastos, Dhammika Nanayakkara and Fábio Ferreira Perazzo

August 2016

Indigenous knowledge and antibacterial activity of selected herbs used locally to treat common cold in Central Uganda

The study documented the medicinal plants used in the treatment of influenza and common cough and established efficacy of some plants locally used against bacteria causing upper respiratory tract infections in Uganda. It involved an ethnobotanical survey and laboratory experimental investigation to determine the bioactivity against selected bacteria that cause upper respiratory tract infections. Data on medicinal...

Author(s): Joel Walugembe, Jacob S. Iramiot and Esther Katuura

August 2016

Citrus reticulata Blanco cv. Santra leaf and fruit peel: A common waste products, volatile oils composition and biological activities

The components of essential oils from the leaf and fruit peel of Citrus reticulata Blanco cv. Santra (santra mandarin) cultivated in Egypt were explored qualitatively and quantitatively using GLC and GLC/MS and 131 components were identified and quantified. In the leaf oil, one hundred and nine (109) compounds were determined with sabinene (23.10%) and linalool (21.20%) as a major component. The total identified...

Author(s): Dalia I. Hamdan, Maged E. Mohamed, and Assem M. El-Shazly

August 2016

Additive effects of Capsaicin Oleoresin, Irbesartan and Amlodipine Besylate” on the blood pressure of spontaneously hypertensive rats

The effects of oral intake of capsaicin oleoresin (CO) on arterial blood pressure was examined in male spontaneously hypertensive (SHR) rats. Animals were randomized into control (C), capsaicin oleoresin (CO), capsaicin oleoresin-irbesartan (COI) and capsaicin oleoresin-amlodipine besylate (COAB) fed groups. The experimental groups received 50 mg of Capsaicin Oleoresin only, CO with 25 mg of Irbesartan, and CO with 2.5...

Author(s): Oyonumo E. Ntekim, Joanne S. Allard, Julius S. Ngwa, Allan A. Johnson, Chimene Castor, Osi Iyalomhe, Thomas V. Fungwe, Chinwe C. Ntekim and Thomas Obisesan

August 2016

Popular medicinal plants used by the Bantu people and Pygmies living in the administrative territories of Beni and Lubero (DRC)

Medicinal plants occupy the most preponderant place in households in Democratic Republic of the Congo. Indeed, more than three quarters of its population depend on natural resources to survive financially and health wise, due to economic issue and inability of some modern medicines to cure some diseases. An ethno-botanical survey was conducted in Beni and Lubero territories, where Bantu people and Pygmies live. It was...

Author(s): Eric Lukwamirwe Kasika, Valentin Kamabu Vasombolwa and Jean Lejoly

August 2016

Isolation of a novel piperidide from Achillea ‘Moonshine’ using bioactivity guided fractionation for the treatment of acne

Achillea millefolium is a flowering plant in the family, Asteraceae and is known to be used in traditional medicine as astringent, stimulant, tonic, antiphlogistic and for the treatment of cold and influenza. In an earlier study in the authors’ laboratory, four different extracts of a variety of yarrow called Achillea ‘Moonshine’ were tested for anti-acne effect. The petroleum ether extract of Achillea...

Author(s): Rahul M. Shah, Tejal Patel, Cristina Maria Tettamanzi, Jesse Rajan, Mamta Shah and Bela Peethambaran,

August 2016

Effect of adding sacha inchi (Plukenetia volubilis L.) seeds to a prototype of convenience food draft, on the nutritional composition and sensory acceptance

The polyunsaturated fatty acids of Sacha Inchi seeds are important in the development of food products with healthy and nourishing properties. The aim of this study was to evaluate the effect of Sacha Inchi (Plukenetia volubilis L) on a prototype convenience food. The nutritional composition and sensory acceptance was evaluated using a completely randomized experimental design. Fixed effect-balanced factorial multiple...

Author(s): Edwin Darío Betancur-Hoyos, Luz Amparo Urango-Marchena and Luis Fernando Restrepo-Betancur

August 2016

Chemical profile, antimicrobial activity, toxicity on Artemia salina and anti-acetylcholinesterase enzyme essential oil from Bauhinia ungulata L. (Fabaceae) leaves

Bauhinia ungulata L. species, belongs to the genus Bauhinia, popularly known as pata de vaca, is among the species of medicinal employ in Brazil, used to treat diabetes. The aim of this study was to characterize the chemical composition, antimicrobial activity, toxicity on Artemia salina and acetylcholinesterase enzyme inhibition by essential oil from B. ungulata L. The chromatographic analysis revealed 18 components,...

Author(s): Sandra R. N. A. Medeiros, Antonio A. de Melo Filho, Habdel N. R. da Costa, Francisco dos Santos Silva, Ricardo C. dos Santos, Jacqueline A.Takahashi, Vany P. Ferraz, Ana C. G. R. de Melo, Pedro R. E. Ribeiro, Andreina G. de Andrade Laranjeira, Angela K. Kamezaki, Regildo M. G. Martins and Flavio da Silva Paulino

August 2016

Antifungal and cytotoxicity activities of Anacardium othonianum extract

The antifungal activities of the crude ethanolic extract of Anacardium othonianum (Anacardiaceae) leaves (EE) and the n-hexane (HF), EtOAc (EF), n-BuOH (BF) and hydromethanolic (HMF) fractions were assayed against Candida albicans (ATCC 64548) and Trichophyton rubrum (Tr1). Additionally, the cytotoxicities were also evaluated against normal human lung fibroblasts (GM07492A). The EE yielded minimum inhibitory...

Author(s): Flávia Maria Lígia Marangoni Jordão Curado, Ana Paula Gazolla, Rita Cassia Nascimento Pedroso, Letícia Pereira Pimenta, Pollyanna Francielli de Oliveira, Denise Crispim Tavares, Márcio Luis Andrade e Silva, Wilson Roberto Cunha, Rosemeire Cristina Linhari Rodrigues Pietro, Ana Helena Januário, Patrícia Mendonça Pauletti, Juliana de Fátima Sales and Fabiano Guimarães Silva

July 2016

The impact of compounds isolated from Ocimum sp. on apoptotic activity of osteoclast

Periodontal disease has multifactorial etiology. The immune response to the microbial challenge leads to osteoclast activation and resorption of the alveolar bone, resulting in tooth loss. Compounds isolated from Ocimum americanum and Ocimum basilicum were analyzed for apoptotic activity towards osteoclast in this study. Steam distillation was used for the extraction of essential oils (EOs) from dry leaves and flowers....

Author(s): Paulo J. L. Juiz , Roberto Gambari, Roberta Piva, Letizia Penolazzi, Franceli Silva, Reinaldo J. C. Alves, Angélica M. Lucchese and Ana Paula T. Uetanabaro

July 2016

The effects of an aqueous leaf extract of Clausena anisata (Willd.) Hook.f.ex Benth. on blood pressure, urine output, angiotensin II levels and cardiac parameters in spontaneously hypertensive rats

Clausena anisata (Willd.) Hook.f. ex Benth (Rutaceae) is a medicinal plant indigenous to Southern Africa and scientific studies report on its biomedical activities and possible antihypertensive property by demonstrating in vitro angiotensin converting enzyme  inhibition. This study investigated the antihypertensive effects of an aqueous leaf extract of Clausena anisata in a spontaneously hypertensive rat model, and...

Author(s): Ntamo MacDonald Tshepo Lechaba, Paul Jacobus Schutte, Leon Hay, Linde Böhmer and Melvin Megandran Govender

July 2016

Cytotoxic effect and antioxidant activity of Andean berry (Vaccinium meridionale Sw) wine

Vaccinium meridonale Sw or Andean berry has antioxidant properties due to its high content of polyphenols, as anthocyanins and phenolic acids. Polyphenols have been associated with the prevention of chronic and cardiovascular diseases. In the last years, alcoholic drinks have been studied for their composition and health benefits. By this, the aim of this research was to obtain three types of alcoholic beverages from...

Author(s): Isabel Cristina Zapata Vahos, Susana Ochoa,  María Elena Maldonado, Arley David Zapata Zapata and Benjamín Rojano

July 2016

Phytochemical screening, total phenolic content and antioxidant activity of some plants from Brazilian flora

The present study evaluated the total phenolic and flavonoid content as well as the antioxidant activity of methanolic leaf extracts of five plants from Brazilian flora: Abarema cochliacarpos, Croton corchoropsis, Myroxylon peruiferum, Stryphnodendron pulcherrimum and Tanaecium cyrtanthum by 2,2’-azino-bis- (3-ethylbenzothiazoline-6-sulfonate) (ABTS), 2,2-diphenyl-1-picrylhydrazyl (DPPH) and total antioxidant...

Author(s): João da Rocha Lins Neto, Amanda Dias de Araújo Uchôa, Priscila Andrade de Moura, Clovis Macêdo Bezerra Filho, Juciara Carneiro Gouveia Tenório, Alexandre Gomes da Silva, Rafael Matos Ximenes, Márcia Vanusa da Silva, and Maria Tereza dos Santos Correia,

July 2016

Liver damage in an experimental model of peripheral neuropathy induced by Karwinskia humboldtiana (Buckthorn) fruit: Histopathological evidence

Karwinskia humboldtiana (Kh) is a poisonous shrub that causes acute or chronic intoxication in animals and humans. In chronic intoxication, the main sign is the presence of paralysis. Previously we reported a model of intoxication with Kh fruit that reproduces paralysis and clinical phases in humans when they do not die; however, there are no studies that describe damage to liver in this model. The objective was to...

Author(s): Rubén García-Garza, Martha E. Salazar-Leal, Viktor J. Romero-Díaz, Jaime García-Juárez, Carlos Leyva-Orasma, Javier Morán-Martínez, Odila Saucedo-Cárdenas, and Adolfo Soto-Domínguez

July 2016

Characterization of the bioactive constituents of Nymphaea alba rhizomes and evaluation of anti-biofilm as well as antioxidant and cytotoxic properties

Anti-biofilm represents an urge to face drug resistance. Nymphaea alba L. flowers and rhizomes have been traditionally used in Ayurvedic medicine for dyspepsia, enteritis, diarrhea and as an antiseptic. This study was designed to identify the main constituents of Nymphaea alba L. rhizomes and their anti-biofilm activity. 70% aqueous ethanolic extract (AEE) of N. alba rhizomes was analyzed by liquid chromatography, high...

Author(s): Riham Omar Bakr, Reham Wasfi, Noha Swilam and Ibrahim Ezz Sallam

July 2016

Modulatory effects of Hilleria latifolia and Laportea ovalifolia on activity of selected antibiotics

Microorganisms are becoming resistant to almost all existing and newly discovered antimicrobial agents. This has led to ineffective treatment of infectious diseases with increased risk of complications. Few medicinal plants have been found to exhibit the ability of reversing the resistance mechanisms of microbes to antibiotics. The study investigates the influence of leaf methanol extracts of Hilleria latifolia and...

Author(s): Susana Oteng Dapaah, Christian Agyare, Yaw Duah Boakye and Theresa Appiah

July 2016

Evaluation of new protocols to Curcuma longa micropropagation: A medicinal and ornamental specie

Turmeric (Curcuma longa) is an Asian native species used for ornamental, medicinal and food purposes. However, its conventional propagation method is costly and inefficient. Therefore, this study aimed to verify appropriate asepsis methods for shoots from rhizomes, evaluate concentrations of activated charcoal and sucrose, and determine appropriate salt concentrations in Murashige and Skoog (MS) medium for turmeric...

Author(s): Meire Pereira de Souza Ferrari, Dirlane Antoniazzi, Andressa Bezerra Nascimento, Larissa Fiama Franz, Camila Silva Bezerra and  Hélida Mara Magalhães

June 2016

Vitamins C and E levels are enhanced by Azadirachta Indica leaves aqueous extract in paracetamol induced hepatoxicity in Wistar rats

Azadirachta indica, used in many parts of the world as herbal medicine, has been reported to be antioxidative and hepatoprotective. This study investigated the effect of leaves aqueous extract of A. indica on plasma levels of vitamins C and E, liver enzymes alanine transaminase (ALT), aspartate transaminase (AST) and alkaline phosphatase (ALP) in Wistar rats with hepatotoxicity. Four groups of twenty Wistar rats each...

Author(s): Emmanuel Ikechukwu Nwobodo, Dennis C. Nwosu, Harrison U. Nwanjo, Augustine C. Ihim, John Kennedy Nnodim, Chinyere I. Nwobodo and Ukamaka C. Edwrad

June 2016

The antimalaria effect of Momordica charantia L. and Mirabilis jalapa leaf extracts using animal model

Momordica charantia L. (Cucurbitaceae) and Mirabilis jalapa L. (Nyctaginaceae) are medicinal plants used extensively in almost all folklore remedies around the world to treat malaria. This experiment investigated the effects of M. charantia L. and M. jalapa L. on malaria in a 4-day suppressive test. Animals received 50, 100, or 200 mg/kg of methanolic extracts orally. M. charantia and M. jalapa methanolic extracts...

Author(s): Akanji Olufunke Christy, Cyril-Olutayo C. Mojisola, Elufioye O.Taiwo and Ogunsusi Omowumi Ola

June 2016

Farmer's knowledge level and training needs toward the production and conservation of medicinal herbal plants in Jordan

The main purpose of the study is to determine farmer's awareness and training needs towards the production of Medicinal and Herbal (M/H) plants in Jordan. A survey questionnaire described the personal characteristics of M/H farmers with sample size population of 209. Results showed the majority of farmers grow thyme, sage, and mint which is a popular M/H plant grown in Jordan. A majority of farmers, 71%, feel that...

Author(s): Laith Moh’d Rousan and Sammar Faiz Al-Uzaizi

June 2016

Syagrus coronata seed oils have antimicrobial action against multidrug-resistant Staphylococcus aureus

Syagrus coronata (Mart.) Becc. (Arecaceae) is a native Brazilian palm (ouricuri) and despite the use of its derived products by traditional communities, few scientific reports have been published regarding its biomedical activity. This study investigates the chemical composition and anti-Staphylococcus aureus effects of both manufactured oil (SCO) and essential oil (SCEO) from S. coronata seeds. SCO was provided by...

Author(s): Cibele Maria Alves da Silva Bessa, Rodrigo Santana do Nascimento, Renata Carla Corrêa Alves, José Matias Anselmo, Ana Paula Sant&#;Anna da Silva, Alexandre Gomes da Silva, Vera Lúcia de Menezes Lima, Josean Fechine Tavares, Luís Cláudio Nascimento da Silva, Márcia Vanusa da Silva and Maria Tereza dos Santos Correia

June 2016

Ethnobotanical and ethnoveterinary study of medicinal plants used in the municipality of Bom Princípio do Piauí, Piauí, Brazil

Knowledge of medicinal plants has accumulated over centuries and often represents the only therapeutic resource of small municipalities in the interior of Brazil. The objective of this study was to evaluate the knowledge and use of medicinal plants by the population of the municipality of Bom Princípio do Piauí, Piauí state, for the treatment of diseases in humans and domestic animals. Interviews...

Author(s): Karina Neoob de Carvalho Castro, Dolores Wolschick, Roberta Rocha Silva Leite, Ivanilza Moreira de Andrade, João Avelar Magalhães and Simon Joseph Mayo

June 2016

Antimicrobial activity of Piper aduncum leaf extracts against the dental plaque bacteria Streptococcus mutans and Streptococcus sanguinis

Piper aduncum has been widely used for medicinal purposes, and it has also been known to possess antimicrobial activity. Dental plaque is a complex ecosystem that harbors benign and pathogenic bacteria. It is desirable that compounds targeted to treat dental plaque-related diseases should be selective in their action, preserving the benign bacteria and inactivating the pathogenic ones. Thus, the study evaluated the...

Author(s): Chaiana Froés Magalhães, Ezequias Pessoa de Siqueira, Elaine Alves de Oliveira, Carlos Leomar Zani, Rodrigo Loreto Peres, Kênia Valéria dos Santos, and Anderson Assunção Andrade,

June 2016

Toxicity and effects of fig (Ficus carica) leaf aqueous extract on haematology and some biochemical indices of wistar albino rats (Rattus norvegicus)

The toxicity and effects of Ficus carica leaf aqueous extract on the haematology and some biochemical parameters were investigated in wistar albino rats for 4 weeks. Various doses (100, 200 and 400 mg/kg body weight) of the extract were administered orally to the rats. The haematological parameters were determined using a Neubauer-type hemocytometer with Toisson’s solution as the diluting fluid for red blood cell...

Author(s): Odo, G. E., Agwu, J. E., Newze, N., Nwadinigwa, A., Onyeke, C. C., Nzekwe, U., Ajuziogu, G. C., Osayi, E. I. and Ikegbunam, C.

June 2016

Phytochemical screening of Xylopia aethiopica with emphasis on its medicinally active principles

This work aimed at investigating the functional types and compositions of bioactive compounds in Xylopia aethiopica. Plant parts (petiole, leaf, seed, stem bark, and roots) were collected from Vandeikya Local Government Area of Benue State, North Central Nigeria. Extracts were qualitatively screened following standard protocols. Phytochemicals were screened and tested. This was followed by quantitative analysis of...

Author(s): C. U. Aguoru, C. Pilla and J. O. Olasan

June 2016

Evaluation of acaricidal efficacy of Synadenium glaucescens (Euphorbiaceae) against boophilus species

Synadenium glaucescens is a traditional medicinal plant used by some communities in Tanzania for the management of various diseases in animals and human including the use for control of ticks in cattle. The aim of this study was to investigate the ‘acaricidal effect’ of extracts from this plant on Boophilus decoloratus and B. microplus. The methodology involved the use of larval and adult immersion tests....

Author(s): Vitus Alberto Nyigo, Robinson Hermmerton Mdegela, Hamisi Massanja Malebo, Faith Philemon Mabiki and Gerda Fouche

June 2016

Eleutherine bulbous (Mill.) Urb.: A review study

Eleutherine bulbous (Mill.) Urb, Iridaceae, is a native plant and quite common in several regions of America, commonly known as “coquinho” being widely used in the folk medicine for the treatment of giardiasis, amoebiasis and diarrhea. This paper presents a literature review of studies about Eleutherine bulbous including aspects of taxonomy, synonymies, geographical distribution, ethnopharmacology, chemistry...

Author(s): Carolyna L. L. Couto, Denise F.C. Moraes, Maria do Socorro S. Cartágenes, Flavia M. M. do Amaral and Rosane N. Guerra

May 2016

Pharmacological Activities of Plectranthus scutellarioides (L.) R.Br. Leaves Extract on Cyclooxygenase and Xanthine Oxidase Enzymes

Plectranthus scutellarioides (L.) R.Br. (family Lamiaceae) has been widely used in West Java, Indonesia, to cure various diseases. People boiled the leaves of the plant in water and consumed the tea daily until the symptoms reduced. This work was conducted to study the pharmacological activity of P. scutellarioides (L.) R.Br. extract on cyclooxygenases (COXs) and xanthine oxidase (XO) enzymes. The plant was purchased...

Author(s): Jutti Levita, Sri Adi Sumiwi, Tiara Indah Pratiwi, Ekky Ilham, Syafrudin Purnama Sidiq and Moelyono Moektiwardoyo

May 2016

Ethnobotanical survey of medicinal plants used in the treatment of women related diseases in Akoko Region of Ondo-State, Nigeria

An ethnobotanical survey was conducted to document medicinal plants commonly used for the treatment of women related diseases by the inhabitants of Akoko in Ondo-State, Nigeria. A total of 36 plants, belonging to 29 families were documented. The abundance status of the identified plants revealed that 24% of the plants were very abundant, 34% were abundant while 42% were scarce. Aframomum melegueta, Ageratunm conyzoides,...

Author(s): Olanipekun M.K. , Arowosegbe  S.,  Kayode  J.O and Oluwole T.R.

May 2016

Antifungal activity of crude extracts of some medicinal plants against Fusarium sp., the pathogen of dirty panicle disease in rice

Antifungal activity of the ethanolic crude extracts of twenty-four medicinal plants namely, Boesenbergia pandurata, Curcuma longa, Zingiber officinale, Alpinia galanga, Zingiber cassumunar, Amonum xanthioides, Kaempferia galanga, Curcuma aromatica, Curcuma xanthorrhiza, Kaemferia parviflora, Amonum krervanh, Syzygium aromaticum, Allium sativum, Allium ascolonicum, Cymbopogon citratus, Cymbopogon nardus, Leptochloa...

Author(s): Sawatdikarn Sanit

May 2016

Isolation and characterization of terpene from leaves of Croton macrostachyus (Bissana)

Croton macrostachyus, one of the Croton species found in Ethiopia, is used traditionally for treatment of a number of health ailments including diabetes, malaria, stomachache, ascariasis, abdominal pain, gonorrhea, wounds, ringworm infestation and hemorrhoids. In the present study, phytochemical screening of ethanol extract from leaves of C. macrostachyus revealed the presence of terpenes, flavonoids, alkaloids and...

Author(s): Abeje Abebayehu, Fikre Mammo and Belayhun Kibret

May 2016

Phytochemical and pharmacological studies of Citharexylum quadrangulare Jacq. leaves

Chromatographic investigation of the Citharexylum quadrangulare leaves led to isolation of nine compounds viz., stigmasterol (1), β-sitosterol (2), oleanolic acid (3), duranterectoside B (4), durantoside I (5), cirsimaritin 4'-O-β-D-glucopyranoside (6), 5-deoxypulchelloside (7), lamiide (8) and cirsimaritin 4'-O-β-D-glucopyranoside 4"-sodium sulphate (9). The compounds (1, 3 and 4) were...

Author(s): Marwa Hassan Hussaen Mohammed, Ashraf Nageeb El-Sayed Hamed, Hany Ezzat Khalil and Mohamed Salah Kamel

May 2016

Inhibitory activity of fractions of Senna nigricans toward protein tyrosine phosphatase 1B and dipeptidyl peptidase IV

Protein tyrosine phosphatase (PTP) 1B and dipeptidyl peptidase (DPP) IV are important in down regulation and secretion of insulin, respectively. While PTP 1B regulates insulin binding to its receptor, DPP IV hydrolyses incretin, which is an important regulator of postprandial insulin secretion. The study evaluated the in vitro inhibitory effect of different fractions of Senna nigricans against PTP IB and DPP IV and the...

Author(s): Yusuf Saidu, Suleiman Alhaji Muhammad, Lawal Suleiman Bilbis and Babangida Muhammad Sani

May 2016

Antifungal activity and synergistic effect of acetophenones isolated from species Croton against dermatophytes and yeasts

The aim of this study was to evaluate acetophenones isolated from Croton spp. for antifungal activity in vitro against Candida albicans, Microsporum canis and Trichophyton rubrum, and to evaluate the toxicity of these substances in vivo. The minimum inhibitory concentration (MIC) and minimum fungicidal concentration (MFC) were determined using the broth microdilution method. The combined effect of the...

Author(s): Francisca Lidiane Linhares de Aguiar, Selene Maia de Morais, Hélcio Silva dos Santos, Maria Rose Jane Ribeiro Albuquerque, Paulo Nogueira Bandeira, Erika Helena Sales de Brito, Marcos Fábio Gadelha Rocha and Raquel Oliveira dos Santos Fontenelle

May 2016

Leaves of Schinus polygamous (Cav.) Cabrera (Anacardiaceae) are a potential source of hepatoprotective and antioxidant phytochemicals

Phytochemical investigation of the crude ethanol extract of the leaves of Schinus polygamus (Cav.) Cabrera (Anacardiaceae) results in isolation of eight compounds identified as triterpenoids, 3-O-acetyllupeol (I), βeta-sitosterol (II), lupeol (III). In addition to the polyphenols, gallic acid (IV), methyl gallate (V), quercetin-3-α-O-rhamnoside (VI), kaempferol (VII) and quercetin (VIII). In Egypt,...

Author(s): Abeer Mohamed El Sayed

April 2016

Chemical composition and biological activities of Pouteria campechiana (Kunth) Baehni

The present study was conducted to evaluate the analgesic, anti-inflammatory and gastroprotective activities of ethanol, de-fatted ethanol extracts and n-hexane fractions of Pouteria campechiana (Kunth) Baehni leaves and seeds. Further chemical analysis was done to isolate and identify its bioactive compounds. The seeds ethanolic extract produced 85% inhibition of inflammation in the rat paw oedema test at the dose of...

Author(s): Aly M. Elsayed, Nebal D. El-Tanbouly, Sherifa F. Moustafa, Rabab M. Abdou and Sally A. W. El Awdan

April 2016

Antifungal activity of selected medicinal plants against Alternaria species: The pathogen of dirty panicle disease in rice

Antifungal activity of the ethanolic crude extracts from ten plants, namely: Curcuma xanthorhiza, Curcuma aromatica,  Kaempferia parviflora, Syzygium aromaticum, Origanum vulgare, Synedrella nodiflora, Sorghum bicolor, Rosmarinus officinalis, Piper longum and Eupatorium odoratum were tested against Alternaria species (the pathogen of dirty panicle disease in rice) by poisoned food technique at 0, 1,000, 2,500,...

Author(s): Sawatdikarn Sanit

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