Journal of
Medicinal Plants Research

  • Abbreviation: J. Med. Plants Res.
  • Language: English
  • ISSN: 1996-0875
  • DOI: 10.5897/JMPR
  • Start Year: 2007
  • Published Articles: 3654

JMPR Articles

April 2015

Haematological parameters, semen characteristics and sperm morphology of male albino rat (wistar strain) treated with Aloe vera gel

Haemograms, semen characteristics and sperm morphology of the male albino rat (wistar strain) treated with Aloe vera gel was studied. A. vera gel has been widely used for both medicinal and non-medicinal purposes. Fifteen male clinically healthy albino rats weighing between 0.15 to 0.24 kg and 16 to 20 weeks of age were randomly assigned to three groups A, B and C. Groups A and B were the experimental groups while Group...

Author(s): Matthew Olugbenga Oyeyemi and Olumide Samuel Ajani

April 2015

Antioxidant and α-amylase inhibition activities in vitro of various solvent extracts of Thymus schimperi Ronniger

Thymus schimperi Ronniger is a wild endemic herb to Ethiopia, and is traditionally used as food flavoring, preservative as well as medicinal ingredient. This paper reports the total phenolic and flavonoid contents, antioxidant capacity and α-amylase inhibition activity of various solvent extracts of the dried leaves. The acetone extracts contained the highest total phenolic content (122.0±11.6 mg GAE/g)....

Author(s): Engeda Dessalegn, Geremew Bultosa, Gulelat Desse Haki and H. P. Vasantha Rupasinghe

April 2015

Isolation and characterization of filaricidal compounds from the stem bark of Voacanga africana, a plant used in the traditional treatment of onchocerciasis in Cameroon

This study was carried out to isolate active ingredients from Voacanga africana Stapf (Apocynaceae) used as herbal medicine in Cameroon, and also to assess the efficacy of the compounds on Onchocerca ochengi and Loa loa worms. The compounds were isolated using solvent partitioning, column chromatography and fractional crystallization. The O. ochengi worms were isolated from cow skin while Loa loa was isolated from...

Author(s): Smith Babiaka Borakaeyabe, James Ajeck Mbah, Fidelis Cho-Ngwa, Jonathan Alunge Metuge, and Simon Mbua Ngale Efange,  

April 2015

Identification of phenolic compounds by high performance liquid chromatography/mass spectrometry (HPLC/MS) and in vitro evaluation of the antioxidant and antimicrobial activities of Ceratonia siliqua leaves extracts

Ceratonia siliqua is a typical plant of the Mediterranean area, which is mainly used as animal and human food and in folk medicine for treating some diseases such as antidiarrheal and diuretic. The present study was planned to evaluate the potential of antimicrobial and antioxidant activities of C. siliqua leaves extract and the identification of bioactive compounds by high performance liquid chromatography/mass...

Author(s): Anis Ben Hsouna, Mohamed Trigui, Raoudha Mezghani Jarraya, Mohamed Damak and Samir Jaoua

April 2015

Effects of 1.8-cineole (eucalyptol) on the spontaneous contractile activity of smooth muscles fibre

Eucalyptus oil is frequently used in phytotherapy. The objective of the present paper was to investigate to what extent 1.8-cineole influences the activity of smooth muscle fibres. The effects of 1.8-cineole on the spontaneous contractile activity were investigated in in vitro experiments with circular smooth muscle fibres of guinea pig stomach. 1.8-cineole was found to have agonistic effects on the a1 and a2 adrenergic...

Author(s): Sagorchev Plamen, Lukanov Julian and Beer André-Michael

April 2015

Morelloflavone and its semisynthetic derivatives as potential novel inhibitors of cysteine and serine proteases

This article reports the three biflavonoids isolated from the fruit pericarp of Garcinia brasiliensis Mart. (Clusiaceae): Morelloflavone-4```-glycoside (compound 1), (±)-Fukugiside (compound 2), and Morelloflavone (compound 3). Structural modifications by acylation and alkylation reactions were performed on the natural biflavonoid (±) morelloflavone to obtain three semisynthetic compounds:...

Author(s): Vanessa Silva Gontijo, Jaqueline Pereira Januário, Wagner Alves de Souza Júdice, Alyne Alexandrino Antunes, Ingridy Ribeiro Cabral, Diego Magno Assis, Maria Aparecida Juliano, Ihosvany Camps, Marcos José Marques, Claudio Viegas Junior and Marcelo Henrique dos Santos

April 2015

One-pot synthesis of potential antioxidant agents, 3-carboxylate coumarin derivatives

A simple and efficient route to synthesize 3-carboxylate coumarin derivatives through three-component one-pot reaction in a single step has been recommended. This method provides a direct and rapid access to get 3-carboxylate coumarin derivatives. The structures of these synthetic products were identified and the antioxidant activities were tested by inhibiting DPPH· and ·OH radicals capacities. The data...

Author(s): Lijuan Han, Bing Huang, Zhiwei Xiong and Chunyan Yan  

April 2015

Antioxidant and cytotoxic activity of black and green tea from Vaccinium meridionale Swartz leaves

Tea is a beverage made from leaves with high contents of polyphenolic substances that vary based on the process they are subjected to. In this study, the apical and young leaves from Vaccinium meridionale (named mortiño) were processed to obtain two kinds of tea: green and black tea. This was done in order to compare their antioxidant activity, content of secondary metabolites at different temperatures of...

Author(s): Isabel Cristina Zapata-Vahos, Verónica Villacorta, María Elena Maldonado, Dagoberto Castro-Restrepo and Benjamín Rojano  

April 2015

Antioxidant capacity of different African seeds and vegetables and correlation with the contents of ascorbic acid, phenolics and flavonoids

The antioxidant capacity of 2 African seeds and 8 vegetables were analyzed using ferric reducing antioxidant power assay (FRAP assay) after water and acetone extractions. The contents of ascorbic acid, phenolics and flavonoids were determined and their correlations with FRAP value were investigated. The results showed that Vernonia amygdalina was stronger (4.84 mM/100 g dry weight (DW)) than other vegetables analyzed in...

Author(s): Edet E. E., Ofem J. E., Igile G. O., Ofem O. E., Zainab D. B. and Akwaowo G.  

April 2015

Effect of Commiphora swynnertonii resin extract on various physiological parameters in chickens

In the current study, various haematological and biochemical parameters of chickens were evaluated following an oral administration of resin extract from Commiphora swynnertonii. Sixty chickens (8 months old) were randomly assigned into 5 groups (n=12): G1 served as a negative control, that is, chickens received normal saline only, while G2 to G5 chickens were given different doses of the resin extract orally for 14...

Author(s): Bakari G. G., Max R. A., Mdegela H. R., Pereka A. E., Phiri E. C. J. and Mtambo M. M. A.  

March 2015

Evaluation of antibacterial activity and modulatory effect of the hexane fraction from methanol extract of Cordia verbenacea DC leaves

Medicinal plants have been used since the beginning of civilization, and even today, it is still widely used mainly due to the lack of necessary information on their physical and chemical components. Cordia verbenacea DC is a typical plant of the Brazilian coast, popularly known as "grass whaling" and is mainly used as antimicrobial agents, anti - inflammatory and analgesic. This study was conducted in order...

Author(s): ALVES Erivania Ferreira, SANTOS Beatriz Sousa, COUTINHO Henrique Douglas Melo, AGUIAR José Junior dos Santos,COSTA José Galberto Martins and MATIAS Edinardo Fagner Ferreira

March 2015

Hepatoprotective medicinal plants used by the Gond and Bhill tribals of District Raisen Madhya Pradesh, India

The ethnobotanical survey of the medicinal plants used in the management of jaundice (hepatic disorder) was carried out in the District Raisen of Madhya Pradesh. The herbalists, herb sellers and traditionalists were interviewed by the administration of questionnaires. Floristically, the area is placed in Malwa plateau region of Madhya Pradesh. Aims of the study were to document the medicinal plant resources and their...

Author(s): Zahoor Ahmad Lone, Yaqoob Lone, Shaukat Saeed Khan, Aijaz Ahmad Wani and Mohd Imran Reshi

March 2015

Anti-inflammatory effects of Portulaca oleracea L. on the LPS-induced RAW 264.7 cells

Portulaca oleracea L. (Portulacaceae) has been widely used as a folk medicine in many countries. The present study investigated the effects of aqueous extract of P. oleracea (PO) on pro-inflammatory mediators secreted from lipopolysaccharide (LPS) - activated macrophage cells (RAW 264.7) as an established inflammation model. The reference drug indomethacin was used for comparison purpose. PO did not show cytotoxic...

Author(s): Young-Ock Kim, Sang-Won Lee, Sae Won Na, Hye Ran Park and Eun Suk Son  

March 2015

Content and chemical composition of the essential oil from Byrsonima verbascifolia Rich. ex a. Juss. collected in different seasons and times of day

Certain factors may influence the special metabolite production in plants. Leaves of Byrsonima verbascifolia (MALPIGHIACEAE) were collected during different seasons and times of day, to determine the concentration and chemical composition of volatile oils. Chemical analysis indicated that oxygenated sesquiterpenes were the most concentrated, and oxygenated monoterpenes were the least concentrated. The primary components...

Author(s): Henrique Antônio de Oliveira Lourenço, Juliana de Fátima Sales, Fabiano Guimarães Silva, Nathália Lopes Ribeiro, Jéssica Leal de Freitas e Souza and Paulo Sérgio Pereira  

March 2015

Note on somatic embryogenesis and synthetic seed production in Angelica glauca: A valuable medicinal plant of Himalaya

This is the first report of somatic embryogenesis and synthetic seed production in Angelica glauca, a valuable medicinal plant of Himalaya. Somatic embryogenesis protocol was developed using leaf explants from newly sprouted rhizomes. Mature leaf explants were inoculated in Murishige and Skoog (MS) medium supplemented with 3 µM 2,4-dichlorophenoxyacetic acid (2,4-D) induced 86% callus. Calli (0.5 g) subcultured...

Author(s): Anil Kumar Bisht, Arvind Bhatt and U. Dhar  

March 2015

Acute toxicity and histopathological assessment of methanol extract of Cleome viscosa (Linn.) whole plant.

Cleome viscosa Linn (Cleomaceae) is a medicinal plant used widely in Nigeria for the management of various ailments.  This research appraised the toxic potential of the plant with a view to validating or contesting its safety. Acute oral toxicity of the methanolic whole plant extract of Cleome viscosa was evaluated in mice using modified Lorke’s method. Signs accompanying toxicity and possible death of...

Author(s): Taiwo O. Elufioye and Joel O. Onoja

March 2015

In vitro antimicrobial activity of “Antibact”, an herbal medicinal product against standard and clinical bacterial isolates

In vitro antimicrobial activities of ethanol and aqueous “Antibact”, herbal products consisting of a combination of the leaves and branches of four different plants were evaluated against twenty one pathogenic bacteria. Saponins, reducing sugars, phenolics, polyuronides, and triterpenes were the major phyto-constituents of both the aqueous and ethanol “Antibact”. The LD50 analysis revealed the...

Author(s): Felix Charles Mills-Robertson, Cynthia Igbukolu Onyeka , Samuel Crowther Kofi Tay and Williams Walana  

March 2015

Antimicrobial activity of Thymus schimperi Ronninger (Lamiaceae) against standard and clinical isolates of human pathogenic bacteria

Thymus schimperi Ronninger (Lamiaceae) locally known as Tosign, is a multipurpose endemic plant that has been used for various remedies as constituents of traditional medicine in Ethiopia. The objective of this study is to evaluate antibacterial activity of water, ethanol, methanol and chloroform extracts of T. schimperi using agar well diffusion and broth dilution methods against human pathogenic bacterial strains....

Author(s): Abreham Bekele, Rahel Abera, Taye Mebratu, Workabebe Dessie, Awokech Getu, Birtukan Getnet

March 2015

Systematic significance and pharmaceutical potentials of trichomes in accessions of Sesamum indicum L. Pedaliaceae

Fresh leaves of twelve accessions of Sesamum indicum were collected after 12 weeks of planting and morphological-histology of trichomes were studied. These features may be used for the delimitation and determination of pharmaceutical potentials of the accessions. These accessions were found to exhibit high degree of heterogeneity in their trichome features. Nine types of trichomes were observed: unicellular, glandular...

Author(s): Daniel Andrawus Zhigila, Fatima BJ Sawa and Suleiman D. Abdul  

March 2015

Assessment of antioxidant capacity of ethanolic extract of Portulaca oleracea leaves in vitro and in vivo

The purpose of the present study was to prepare ethanol extract of Portulaca oleracea L. leaves (PLE) that is rich in phenolic compounds and investigate there in vitro and in vivo antioxidative activities using ethanol to induce oxidative stress in the liver. This study includes two phases. The first phase includes assessment of antioxidant capacity in vitro using 1,1- Diphenyl-2-picrylhydrazyl (DPPH) assay and...

Author(s): Hefnawy Taha and Ali Osman

March 2015

Antimicrobial and efflux pumps inhibitory activities of Eucalyptus grandis essential oil against respiratory tract infectious bacteria

Essential oils obtained by hydrodistillation from the fresh and dry leaves of Eucalyptus grandis were analyzed by gas chromatography (GC) and gas chromatography mass spectrometry (GC-MS). The main components of the fresh leaf oil were α-pinene (29.6%), p-cymene (19.8%), 1,8-cineole (12.8%) and α-terpineol (6.4%). While, the dry leaf oil had 1,8-cineole (47.4%), limonene (13.3%), α-pinene (7.5%) and...

Author(s): Soyingbe Oluwagbemiga Sewanu, Myeni Cebile Bongekile, Osunsanmi Oluwagbemiga Folusho, Lawal Oladipupo Adejumobi, and Opoku Andrew Rowland  

March 2015

Determination of alkaloid compounds of Ricinus communis by using gas chromatography- mass spectroscopy (GC-MS)

In this study, the alkaloid compounds of Ricinus communis have been evaluated. The chemical compositions of the leaf ethanol extract of R. communis were investigated using gas chromatography-mass spectroscopy (GC-MS). GC-MS analysis of R. communis alkaloid leaf ethanol extract revealed the existence of the n-haxadecanoic acid, octadecanoic acid, 1-hexadecanol. 2-Methyl, gibb-3-ene-1. 10decarboxylic acid , 2,4a....

Author(s): Ameera Omran Hussein, Imad Hadi Hameed, Huda Jasim and Muhanned Abdulhasan Kareem

March 2015

Karyotype analysis of obtained tetraploid in medicinal plant (Platycodon grandiflorus)

Platycodon grandiflorus is an important medicinal plant in China. Induction of polyploidy was successfully attempted in this medicinal plant using 0.05% colchicine semi-solid under 72 h by apical shoot tip treatment of young seedlings, and then 50% mutant plants were obtained. It was testified by the chromosome number in mitosis and its karyotype analysis for diploid control and obtained mutants. The results showed that...

Author(s): Fuhong Yang, Lingjiao Li, Erhua Rong, Yongbo He, Xiaoming Zhao and Yuxiang Wu  

March 2015

Comparison of allopathic and herbal medicine for the treatment of Entamoeba histolytica: A double blind clinical trial

This parallel, randomized, double blind clinical trial was designed to compare allopathic drugs [a combination of metronidazole + diloxanide furoate (MDF)] with Endemali (herbal product) for therapeutic cure rate and side effects in order to find out the most suitable drug for this killer disease. This double blind randomized clinical trial was conducted in two areas of Karachi, Pakistan after approval from ethical...

Author(s): Muhammad Irfanullah Siddiqui, and Khan Usmanghani  

March 2015

Phytochemical, antioxidant and cytotoxic analysis of Brazilian cerrado plants: Preliminary evidence of their antitumor activity

The aim of this study was to analyze the antitumor activity of Anacardium humile A. St.-Hil., Brosimum gaudichaudii Trécul and Tabebuia avellanedae Lorentz ex Griseb species, which are distributed in the Cerrado region of Brazil. Qualitative and quantitative analyses were also conducted on the bark and leaf extracts and antioxidant and cytotoxic activities were studied. The results showed that the bark and leaf...

Author(s): Thiago Antônio de Sousa Araújo⊃,⊃, Tadeu José da Silva Peixoto Sobrinho⊃, Jaciana dos Santos Aguiar⊃, Ana Carolina Oliveira da Silva⊃, Felipe Uchôa Brito⊃, Teresinha Gonçalves da Silva⊃, Elba Lucia Cavalcanti de Amorim⊃ and Maria Cristina da Silva Pranchevicius,  

March 2015

Podophyllotoxin content in rhizome and root samples of Podophyllum hexandrum Royle populations from Indian Himalayan region

The podophyllotoxin content in rhizome and root samples of Podophyllum hexandrum Royle (with leaf morphological variants, that is, 1, 2 and 3L), an endangered perennial herb and a source of highly valued aryltetralin lignan, collected from 17 different populations (2800 to 3600 m asl) spread across Uttarakhand State of Indian Central Himalaya were analyzed by high performance liquid chromatography (HPLC).  In...

Author(s): Hemant Pandey, Anil Kumar, Lok Man S. Palni, and Shyamal K. Nandi  

March 2015

Alkaloid constitution of Nerium oleander using gas chromatography-mass spectroscopy (GC-MS)

Oleander is an evergreen shrub or small tree from 5 to 25-ft tall containing gummy sticky sap in the dogbane family Apocynaceae. In this study, the alkaloid compounds of Nerium oleander (NO) have been evaluated. The chemical compositions of the leaf ethanol extract of N. oleander were investigated using gas chromatography-mass specroscopy (GC-MS). GC-MS analysis of N. oleander alkaloid leaf ethanol extract revealed the...

Author(s): Imad Hadi Hameed, Huda Jasim, Muhanned Abdulhasan Kareem and Ameera Omran Hussein  

February 2015

Lectin isolated from Brazilian seeds of velvet bean (Mucuna pruriens (L) DC.) presents analgesic, anti-inflammatory and antihemolytic action

Lectins are proteins present in all living beings capable of interacting specifically and reversibly to carbohydrates or glycoconjugates form. They stand out in this family of lectins legumes, which are of special scientific interest because they have different biological functions. This study investigated the presence of a lectin in Brazilian seeds of Mucuna, proceeding with their isolation and evaluation of its...

Author(s): Rodrigo Rodrigues e Lacerda, Italo Cordeiro Moreira, Jader Sabino Jacó do Nascimento, Ana Carenina Sampaio de Lacerda, Natasha Lucena Cabral, Daniel Luna Lucetti, Glauce Socorro de Barros Viana, Cícero Francisco Bezerra Felipe, Hilzeth de Luna Freire Pessoa, Carlos Alberto de Almeida Gadelha and Tatiane Santi-Gadelha  

February 2015

Essential oil of Cymbopogon flexuosus, Vernonia polyanthes and potassium phosphite in control of bean anthracnose

This study evaluated essential oils of Cymbopogon flexuosus (EOC), Vernonia polyanthes (EOV), and potassium phosphite (PP) in control of bean anthracnose caused by Colletotrichum lindemuthianum. This study assessed mycelial growth and conidial germination in vitro, scanning electron microscopy (SEM), and enzymes peroxidase (POX) and phenylalanine ammonia-lyase (PAL). EOC and EOV in doses 1,450 and 1,320 μL L-1...

Author(s): Jhonata Lemos da Silva, Paulo Estevão de Souza, Eduardo Alves, Jose Eduardo Brasil Pereira Pinto, Suzan Kelly Vilela Bertolucci, Marcelo Loran Oliveira Freitas, Camila Cristina Lage de Andrade and Mario Lucio Vilela Resende  

February 2015

In vitro anti-Salmonella activity of extracts from selected Kenyan medicinal plants

The aim of this study was to determine in vitro anti-Salmonella activity of extracts of five selected Kenyan medicinal plants against Salmonella ser. Typhi and Salmonella ser. Typhimurium. The extracts from Tithonia diversifolia, Warburgia ugandesis, Croton megalocarpus, Carissa edulis and Launae cornuta plants traditionally used in treatment of typhoid fever were screened for anti-Salmonella activity using disc...

Author(s): Peter Ogoti, Esther Magiri, Gabriel Magoma, Daniel Kariuki and Christine Bii

February 2015

Ameliorative potentials of medicinal plants on the pathophysiological complications of diabetes mellitus: A review

Diabetes mellitus is a metabolic disorder with grievous pathophysiological complications which affect various parts of the body and manifesting in different ways which include acute and chronic neuropathy, nephropathy, gastropathy, retinopathy, micro and macro cardiovascular disorders and erectile dysfunction. Incidence and prevalence of diabetes mellitus is fast becoming high in middle and low income countries where...

Author(s): Adeyi Akindele O., Nneji Lotanna, M. and Idowu Babatunde A.  

February 2015

Lipid profile status of streptozotocin induced diabetic rats treated with ethanolic leaf extract of Solenostemon monostachyus

Lipid profile status of streptozotocin induced diabetic rats treated with ethanolic leaf extract of Solenostemon monostachyus was assessed. A total of 24 rats were used for the experiments and were divided into four groups (that is, Diabetic Control (DC), Normal Control (NC), Insulin Treated (INS) and S. monostachyus (SM) treated groups), with 6 rats each. The extract, 250 mg/kg body weight, was administered twice daily...

Author(s): Dennis Amaechi, E. O. Udosen, E. E. Edet, E. E. Asanga and I. E. Mbakwe  

February 2015

Influence of extraction method on antibacterial activity of ethanolic extracts of Ocimum gratissimum L.

The aim of this study was to define whether novel extraction methods such as microwave and ultrasound could obtain the most effective ethanolic extracts of Ocimum gratissimum as antibacterial agents. These extracts were compared with respect to extractive yield, eugenol content, antibacterial activity and brine-shrimp (Artemia salina) toxicity with extracts obtained by the classical procedures of maceration and Soxhlet....

Author(s): Lenise de Lima Silva, Clarissa Giesel Heldwein, Luiz Gustavo Brenner Reetz, Rosmari Hörner, Diogo Pompéu de Moraes, Fábio Andrei Duarte, Érico Marlon de Moraes Flores, Renato Zanella, Ana Maria Soares Pereira and Berta Maria Heinzmann,  

February 2015

Identification of flavonol glycosides and in vitro photoprotective and antioxidant activities of Triplaris gardneriana Wedd

Triplaris gardneriana belongs to the family Polygonaceae, known for producing a number of biologically important molecules. The present study was aimed at identifying and quantify its total flavonoid content and determining the antioxidant and photoprotective potential of the plant’s leaves. The flavonoids present in the extract and fractions were analyzed using Liquid chromatography–mass spectrometry...

Author(s): Macedo Sandra Kelle Souza, Almeida Tamires dos Santos, Ferraz Christiane Adrielly Alves, Oliveira Ana Paula, Anjos Victor Hugo Almeida, Siqueira Filho José Alves, Araújo Edigênia Cavalcante da Cruz, Almeida Jackson Roberto Guedes da Silva, Silva Naiane Darklei Santos and Nunes Xirley Pereira  

February 2015

Pharmaco-toxic characterization of the aqueous extract from Pereskia grandifolia leaves

Medicinal plants are rich sources of bioactive compounds with potential for therapeutic, cosmetic and food use, and the species Pereskia grandifolia is widely used by low-income populations for nutritional and medicinal purposes. The objective of this study was to evaluate the pharmaco-toxic potential of the aqueous extract from P. grandifolia leaves, in order to obtain information on the safety of its use. P....

Author(s): Anderson Assaid Simão, Angelita Duarte corrêa, Thaís Cristina Lima de Carvalho, Pedro Henrique Souza Cesar, Carlos Henrique de Moura Oliveira and Silvana Marcussi  

February 2015

Assessment of the genotoxic and antigenotoxic potential of crude extracts and fractions of Schwartzia brasiliensis (Choisy) Bedell ex Giraldo-Cañas

Schwartzia brasiliensis (Marcgraviaceae) is a native Brazilian shrub species with neotropical distribution in shoal environments. Recent studies have revealed its medicinal potential for some human diseases; therefore, this study aimed to evaluate the genotoxic and antigenotoxic potential of extracts and fractions obtained from different organs of S. brasiliensis. To accomplish this, plant extracts at different...

Author(s): Mello G. S., De Mattos J. C. P., Amaral A. C. F., Amorim L. M. F., Caldeira-de-Araujo A. and Albarello N.

February 2015

Ethnobotanical survey and in vitro antiplasmodial activity of medicinal plants used to treat malaria in Kagera and Lindi regions, Tanzania

Tanzania has over 12,000 plant species, some of which are endemic and have potential to yield useful medicines. This study seeks to document such plants used as traditional medicines for treatment of malaria in Kagera region of northwestern Tanzania and Lindi region in south eastern Tanzania. The study also reports on the antiplasmodial activity against chloroquine-resistant Plasmodium falciparum (Dd2) strain of some of...

Author(s): Ramadhani S.O. Nondo, Denis Zofou, Mainen J. Moshi, Paul Erasto, Samuel Wanji, Moses N. Ngemenya, Vincent P.K. Titanji, Abdul W. Kidukuli and Pax J. Masimba  

February 2015

Comparative studies between the chemical constituents and biological properties of the extracts from the leaves and barks of Myracrodruon urundeuva Fr. All.

The present study describes the comparation between the chemical constituents and biological properties of leaves and barks of Myracrodruon urundeuva for proposing the medicinal use of the plant from leaves, avoiding the degradation by remotion of the barks. The results of chromatographic profile of the hydroalcoholic extracts and fractions of leaves and barks showed similarities in the composition of the...

Author(s): Bárbara Caroline Ferreira Mota, Vanessa de Andrade Royo, Jaciara Maria Soares Fonseca, Ariadna Conceição dos Santos, Afrânio Farias de Melo Júnior, Elytânia Veiga Menezes, Viviane Rodrigues Esperandim and Rosangela da Silva Laurentiz  

February 2015

The effect of growth regulators on two different in vitro-cultured explants of Carapa guianensis

Carapa guianensis Aubl. (Meliaceae), known locally as andiroba, is a multi-use species from Amazonia. Andiroba oil is considered an important natural product in the Brazilian market, and international demand is increasing due to its cosmetic and pharmaceutical potential. C. guianensis trees produce seed irregularly over different harvest periods, leading to inconsistent oil production and difficulties with supply. No...

Author(s): Larisse Lobo de Oliveira, Anaíze Borges Henriques, Andrea Furtado Macedo,  

February 2015

Antioxidant evaluations of polar and non-polar fractions of Cajanus cajan seeds

Cajanus cajan (L) Millsp., named Arhar in Hindi and Pigeon pea in English, is an important grain crop of rain-fed agriculture in semi-arid tropics, belonging to family Leguminosae. It is a food and a forage crop, rich in proteins with amino acids like methionine, lysine and tryptophan. Extensive studies on chemical composition of C. cajan have been done during last few decades. This article presents an overview of...

Author(s): Raisa Khanum, Farhana Mazhar and Muhammad Jahangir

February 2015

Light spectra affect the morphoanatomical and chemical features of clonal Phyllanthus tenellus Roxb. grown in vitro

Phyllanthus tenellus Roxb. is a widely distributed tropical medicinal plant and highly valued for its therapeutic properties. Since variable light conditions can significantly alter phenolic compounds that are the main therapeutic constituents of P. tenellus, including tannins and flavonoids, the development of this plant and its chemical metabolism in response to different light spectra were investigated. To accomplish...

Author(s): Cristiane Pimentel Victório, Marcos Vinicius Leal-Costa, Eliana Schwartz Tavares, Ricardo Machado Kuster and Celso Luiz Salgueiro Lage,  

February 2015

Effect of Ginkgo biloba extract on sperm quality, serum testosterone concentration and histometric analysis of testes from adult Wistar rats

Ginkgo biloba extract is a widely consumed phytotherapic used mainly in the treatment of dementia and Alzheimer’s disease, and it has also been employed to treat erectile dysfunction and as an aphrodisiac. This work was aimed at evaluating its effect on sperm quality, serum testosterone concentration and on the histometric analysis of the testes from adult male Wistar rats. Three-month-old Wistar rats were treated...

Author(s): Leonardo Toshio Oshio, Cláudia Cristina Teixeira Ribeiro, Renato Macedo Marques, Martha de Oliveira Guerra, Sérgio Luis Pinto da Matta, João Evangelista de Paula Reis, Rita de Cássia da Silveira e Sá, Leandro Vespoli Campos  and Vera Maria Peters  

February 2015

In vitro and in vivo evaluation of quinones from Auxemma oncocalyx Taub. on Leishmania braziliensis

The effect of a quinone fraction (QF) isolated from the heartwood of Auxemma oncocalyx Taub. was investigated in vitro and in vivo on Leishmania braziliensis. Although QF (1-10 μg/mL) showing marked in vitro anti-Leishmania activity (81 to 94%), the oral treatment with the compound did not protect hamsters against progressive L. braziliensis infection. When QF was administered intraperitoneally (20 mg/kg) the lesion...

Author(s): Sayonara de Melo Viana, Maria Augusta D. Ferreira, Priscila Valera Guerra, Glauce S. Barros Viana and Maria Jania Teixeira  

February 2015

Libidibia ferrea (Mart. ex Tul.) L. P. Queiroz: A review of the biological activities and phytochemical composition

Libidibia ferrea (Mart. ex Tul.) L. P. Queiroz is a medicinal plant widely known in Brazil as “jucá” or “pauferro” that belongs to the Fabaceae family. The species is native to Brazil and is mainly found in the North and Northeastern regions. It has been studied for its biological activities and chemical composition. Scientific literature has reported that this species contains different...

Author(s): Magda Rhayanny Assunção Ferreira, and Luiz Alberto Lira Soares,  

February 2015

Evaluation of membrane stabilizing, anthelmintic, antioxidant activity with phytochemical screening of methanolic extract of Neolamarckia cadamba fruits

The current study was directed on methanolic extract of Neolamarckia cadamba fruits, belonging to the family Rubiaceae, to reveal the possible phytochemicals existence and also to evaluate the membrane stabilizing, anthelmintic, antioxidant properties. To estimate the membrane stabilizing activity, both heat and hypotonic solution induced haemolysis techniques were used. The anthelmintic test was conducted on earthworm...

Author(s): Tairin Islam, Abhijit Das, Kumar Bishawjit Shill, Palash Karmakar, Shafiul Islam and Mohammad Mafruhi Sattar  

January 2015

Antioxidant activity and total phenolic contents of some date varieties from Saravan Region, Baluchistan, Iran

In this study, fruits of six soft cultivars of date palm (Phoenix dactylifera L.) commonly grown in Saravan (Sistan and Baluchistan province) were analysed for their antioxidant activities using 2,2-diphenyl-1-picrylhydrazyl (DPPH) and ferric reducing antioxidant power (FRAP) methods. As well, total phenolic contents were evaluated by Folin-Ciocalteu reagent. The antioxidant power of fruits was in range of 236.82 to...

Author(s): Zahra Sadeghi, Jafar Valizadeh and Omid Azizian Shermeh  

January 2015

Pharmacognostic analyses and evaluation of the in vitro antimicrobial activity of Acmella oleracea (L.) RK Jansen (Jambu) floral extract and fractions

Acmella oleracea (L) RK Jansen is a typical plant species of Northern Brazil, used in gastronomy and in the Amazonian folk medicine of Para State as analgesic, to treat diseases of the mouth and throat. In industry, extracts of this genus have been used in oral hygiene products and in food compositions, as refreshing and flavoring agent, and is also used in cosmetics and toiletry. This paper reports the pharmacognostic...

Author(s): Bianca Nascimento de Alcantara, Yuri Teichi Kobayashi, Karla Fabiana Barroso, Ianna Dias Ribeiro da Silva, Milton Begeres de Almeida and Wagner Luiz Ramos Barbosa  

January 2015

Antimicrobial and antioxidant activities of Blumea lanceolaria (Roxb.)

Medicinal plants are being used for the treatment of several ailments by the local tribes in Mizoram, North East India. The present study was focused to analyze the antibacterial and antioxidant activities of a widely used traditional medicinal plant, Blumea lanceolaria. Total phenol content was found to be high in the ethanolic extract of leaf (33.91 mg GAE/g DW) in comparison to root and stem of the plant. Reducing...

Author(s): Vineet Kumar Mishra, Ajit Kumar Passari, K. Vanlalhmangaihi, Nachimuthu Senthil Kumar and Bhim Pratap Singh

January 2015

Antitermitic activity of plant essential oils and their major constituentsagainst termite Heterotermes sulcatus (Isoptera: Rhinotermitidae)

Termiticide potential of six plant derived essential oils and their thirteen major active chemical constituents were investigated for their termiticidal activities against the termites, Heterotermes sulcatus Mathews 1977 (Isoptera: Rhinotermitidae) using no-choice bioassay method. Responses varied with different plant essential oils and their major chemical constituents at a fixed oil concentration. Among the essential...

Author(s): Mayra L. S. Almeida, Angélica S. Oliveira, Allane A. Rodrigues, Gabriel S. Carvalho, Luciana B. Silva, João H. G. Lago and Fabiana E. Casarin,  

January 2015

Anti-inflammatory and immunoregulatory properties of fractions from Sargentodoxa cuneata ethanol extract

Sargentodoxa cuneata is widely used in the treatment of rheumatic arthritis in China. This study was conducted to investigate the anti-inflammatory and immunoregulatory activities of the ethanol extracts from S. cuneata and analyze the bioactive constituents. The ethyl acetate (ESCe), dichloromethane (ESCd) and aqueous (ESCa) fractions at a dose of 200 mg/kg significantly inhibited mice ear edema. Furthermore, the ethyl...

Author(s): Ruili Ma, Huifang Sun, Jian Tang#, Opeyemi Olatunji, Rong Zhang, Aun Raza Zhaoliang Su, Fusheng Wang, Zhen Ouyang and Huaxi Xu  

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