Journal of
Medicinal Plants Research

  • Abbreviation: J. Med. Plants Res.
  • Language: English
  • ISSN: 1996-0875
  • DOI: 10.5897/JMPR
  • Start Year: 2007
  • Published Articles: 3704

JMPR Articles

Isoliquiritigenin and β-sitosterol from Cissus polyantha Tuber Glig and Brandt

September 2015

Chemical investigation into the composition of Cissus polyantha tuber, a plant used in Northern Nigerian ethno medicine for managing inflammatory conditions and conjunctivitis has led to the isolation of a chalcone from the ethyl acetate and a steroid from the hexane soluble fractions of its methanol extract. The structures of these compounds were elucidated by extensive analysis of their spectroscopic data, including 1...

Author(s): Y. M. Sani, A. M. Musa, N. Tajuddeen, S. M. Abdullahi, M. I. Abdullahi, U. U. Pateh and A. Y. Idris

Chemical composition, antimicrobial and anti-acetylcholinesterase activities of essential oil from Lantana camara (Verbenaceae) flowers

September 2015

Lantana camara L. is considered a weed, but is used in agriculture and traditional medicine due to its different pharmacological effects. The objective of this study was to determine the chemical composition and the bioactivity of essential oil from L. camara flowers collected in Boa Vista, Roraima, Brazil. Essential oil was obtained using a Clevenger type apparatus. The oil obtained was analyzed by gas chromatography...

Author(s): Ricardo Carvalho dos Santos, Antonio Alves de Melo Filho, Edvan Alves Chagas, Jacqueline Aparecida Takahashi, Vany Perpetua Ferraz, Ismael Montero Fernández, Pedro Romulo Estevam Ribeiro, Ana Cristina Gonçalves Reis de Melo and Luciana Chaves Holanda

In vitro evaluation of antidiabetic and antioxidant activity of Seabuckthorn (Hippophae rhamnoides L.) leaves

September 2015

Seabuckthorn (Hippophae rhamnoides L.) is thorny nitrogen fixing deciduous shrub native to Asia and Europe. The present study was undertaken to evaluate the antidiabetic and antioxidant effect of two different extracts, namely, methanolic and aqueous of seabuckthorn (H. rhamnoides L.) leaves by in vitro assays. Seabuckthorn leaves were procured from Lahul area of H.P. Leaves were dried and subjected to methanolic and...

Author(s): Pallavi Bhardwaj, Chandresh Varshneya, Kanika Kaistha and Tammana Tandon  

Phytochemical analysis of the roots of Senna didymobotrya

September 2015

Senna didymobotrya is a plant traditionally used for treatment of sexually transmitted diseases, purgative, appetizer, skin diseases, insecticidal and antibiotic. Phytochemical screening of the CH2Cl2/CH3OH (1:1) and CH3OH (100%) roots extract of the plant revealed the presence of phenolic compounds, anthraquinones, tannins, saponins, napthoquinones and terpenes. Silica gel column chromatographic separation of...

Author(s): Israel Alemayehu, Sisay Tadesse, Fikre Mammo, Belayhun Kibret and Milkyas Endale  

Review of twelve West Africa medicinal plants: Active phytochemical combinations in direct biochemically wound healing process

September 2015

The aim of wound care is to promote wound healing in the shortest time possible, and plants are a great source of medicines, especially in traditional medicine. Traditionally, medicinal plants have been used for many years as topical and internal preparations to promote wound repair. This work will give an overview of twelve West Africa medicinal plant studies and their active phytochemicals in direct wound healing. The...

Author(s): Akpalo Edefia, Amivi Tete-Benissan, Kwami Awaga and Koffi Akpagana  

The antibacterial and antidiarreal activities of the crude methanolic Syzygium cordatum [S.Ncik, 48 (UZ)] fruit pulp and seed extracts

September 2015

Diarrheal infections are the major cause of high morbidity and mortality rates, especially in the developing countries. Different parts (roots, bark and leaves) of the species Syzygium cordatum have been used as antidiarrheal extracts with the exception of its fruit-pulps and seeds. This study aimed at evaluating the antibacterial and antidiarrheal activity of S. cordatum pulp and seed extracts so to find newer and more...

Author(s): Maliehe Tsolanku Sidney, Shandu Jabulani Siyabonga and Basson Albertus Kotze  

In-vitro effects of almond oil, barks and leaves extracts of Baillonella toxisperma (Pierre) against Trichophyton soudanense and Trichophyton rubrum

September 2015

The purpose of this study was to evaluate anti-trichophytic effects of Baillonella toxisperma (Pierre) extracts against Trichophyton rubrum and Trichophyton soudanense. The tests were performed by the agar dilution method and the results have showed the effective inhibition of the mycelia growth of theses strains by B. toxisperma (Pierre) extracts. After 7 days of incubation at 28°C, the percentages of mycelia...

Author(s): S. H. Riwom Essama, M. A. Nyegue, C. Ndoye Foe, S. P. Bouopda Tamoand and F. X. Etoa

An aqueous Citrillus colocynthis peel extract inhibits neutrophil reactive oxygen species production and attenuates lung inflammation in mice

August 2015

Citrillus colocynthis peel aqueous extract (CCPAE) is widely used to treat disorders such as inflammation, ulcers and infections, but its pharmacological target is not known. The objectives of this work were to study the effect of C. colocynthis peel aqueous extract, on human neutrophil reactive oxygen species (ROS) production in vitro, and to evaluate its protective effect on lipopolysaccharide (LPS)-induced lung...

Author(s): Fatma Zioud, Amira Ben Mahmoud, Tarak Boussetta, Jamel El-Benna, and Rafik Bachoual

Assessment of Indian medicinal plants for the treatment of asthma

August 2015

The present study documented the traditional knowledge of medicinal plants which are used for the treatment of respiratory diseases asthma in India by various tribal communities. The present study is based on the literature survey from various sources and it provides a comprehensive knowledge about the use of plants and their parts for the treatment of asthma by various tribal communities in India. Ethno-medicinal uses...

Author(s): Kuldip S. Dogra, Sandeep Chauhan and Jeewan S. Jalal

Effect of biofarming techniques on medicinal glori lily (Gloriosa superba L.) and soil fertility status

August 2015

Field experiment was conducted at the farmer’s field at Devanur village of Ariyalur District, Tamil nadu during 2007 to 2008 to study the effect of biofarming techniques on the yield and soil fertility performance of glori lily (Gloriosa superba L.). The treatments consisted of different organic manures viz.,  T1-control, T2-Farm Yard Manure (FYM) at 12.5 t ha-1, T3- Enriched Farm Yard Manure (EFYM) at 750 kg...

Author(s): S. Deivasigamani, K.Thanunathan, R. M. Kathiresan, M. Sudhakar and B. Bharathi Karthikeyan

Evaluation of the effect of crude extract of Datura innoxia on the cardiovascular action of detomidine in rabbits

August 2015

Datura innoxia indigenous shrub in South Asia region belongs to the family Solanaceae which contains medicinal important alkaloids (hyoscine, atropine, hycosamine, etc). Thirty adult rabbits of mixed breed, male and female were pretreated with 0.1 mg/500 mg of crude extract (1% of dimethyl sulfoxide (DMSO) solution) and injected 5 min later with 0.01 mg/500 mg of detomidine (group A, n=15) or Saline (group B, n=15)....

Author(s): S. U. Rehman, H. M. Rafique, F. A. Qureshi and S. Shahid

Ethnobotanical survey of medicinal plants used by the community of Sobradinho, Luís Correia, Piauí, Brazil

August 2015

An ethnobotanical survey of medicinal plants used by the Sobradinho community, Luís Correia, Piauí, Brazil was undertaken to recover and document traditional knowledge with the aim of supporting chemical, biological, agronomic, pharmaceutical and socio-economic studies related to the region's biodiversity. Fifteen research visits to the community were made between March 2013 to January 2014 involving...

Author(s): Silva J. D. A., Nascimento M. G. P., Grazina L. G., Castro K. N. C., Mayo S. J. and Andrade I. M.

A review on antimicrobial potential of species of the genus Vernonia (Asteraceae)

August 2015

Natural products are sources of various biologically active chemicals. Therefore, ethnopharmacological and ethnobotanical studies are essential to discover new substances for the treatment of diseases. In this context, many studies have been conducted of the Asteraceae family demonstrating medicinal properties of its representatives, such as species of the genus Vernonia, which are rich in bioactive substances like...

Author(s): Antonio Carlos Nogueira Sobrinho, Elnatan Bezerra de Souza and Raquel Oliveira dos Santos Fontenelle

Effect of the speed of the drying air on the quality of essential oil from Aristolochia cymbifera Mart. and Zucc.

August 2015

Dehydrating plant material ensures the conservation of active compounds in medicinal plants. Thus, the object of the present study was to evaluate the effect of three drying air speeds on the content and the chemical composition of essential oil from Aristolochia cymbifera Mart. and Zucc. The tests were conducted in a fixed-layer dryer with drying chambers measuring 0.60 x 0.60 x 0.60 m on a plate with 25% perforation....

Author(s): André Luiz Montes, Daniel Emanuel Cabral de Oliveira, Osvaldo Resende, Fabiano Guimarães Silva and Juliana de Fátima Sales

Isolation and analgesic property of lupeol from Diospyros mespiliformis stem bark

August 2015

Diospyros mespiliformis Hochst (Ebenaceae) stem bark is used in traditional medicine for the management of pain related ailments. Several bioactive compounds have previously been isolated from the plant material that includes pentacyclic triterpenes.  This study sequentially extracted and carried out a bioassay-guided fractionation of the plant crude material with solvents of varying polarity using analgesic...

Author(s): Bulus Adzu, Ben Ahmed Chindo, Florence David Tarfa, Oluwakanyinsola Adeola Salawu and Ogbaji John Igoli

Ethnobotanical study of some medicinal plants from Hoggar, Algeria

August 2015

Study was conducted from July, 2011 to March, 2012 to explore and enumerate the medicinal uses of some plants in folkloric medicine of Hoggar (Algerian Sahara). Semi-structured questionnaires were used to conduct interviews with traditional healers, herb sellers and other knowledgeable individuals on use of medicinal plants. The informants (100) consist of 63% females and 37% males of which 6% were traditional healers,...

Author(s): Farah Ramdane, Mahfoud Hadj Mahammed, Mohamed Didi Ould Hadj, Amoura  Chanai, Roukia Hammoudi, Naima Hillali, Houria Mesrouk, Imane Bouafia and Chaima Bahaz  

Impact of certain Solanum species’s natural products as potent cytotoxic and anti-Inflammatory agents

August 2015

The present study was conducted to evaluate both the cytotoxic and anti-inflammatory activities of ethanol extracts (T), and both n-butanol (B) and total glyco-alkaloid fractions (TGA) of Solanum seaforthianum Andr. (SS) and Solanum macrocarpon L. (SM) growing in Egypt. Cytotoxic activity was measured using sulforhodamine B (SRB) assay on prostate cancer cell line (PC-3), breast cancer cell line (MCF7), liver cancer...

Author(s): Muhammad A. Alsherbiny, Shahira M. Ezzat, Fatma S. Elsakhawy, Gehan M. Kamel and Mostafa A. Abdel-Kawy

Effects of organic fertilizer in the capsaicinoids of red pepper (Capsicum baccatum L.)

August 2015

This study aimed to quantify the contents of capsaicinoids (capsaicin, dihydrocapsaicin and nordihydrocapsaicin) in the Capsicum baccatum L. species grown in soil with different concentrations of organic fertilizer (0, 1, 2 and 4%). The quantification of capsaicinoids was made by reverse-phase chromatography using the high-performance liquid technique (HPLC) with ultraviolet (UV) detection. The peppers were harvested...

Author(s): Andréia Assamy Guinoza, Jackeline Guinoza Siraichi, Zilda Cristiani Gazim, Diógenes Aparício Garcia Cortez and Lucia Elaine Ranieri Cortez

Role of sacred groves in the conservation and management of medicinal plants

August 2015

Sacred groves play a vital role in context of sustainable use and conservation of medicinal plants. The involvement of local communities offers several advantages in the management of traditionally known medicinal wealth of forests. Considering the importance of sacred groves in the conservation of medicinal plants, a study was carried out in Phulbani forest division of Odisha to record the status, distribution and use...

Author(s): Manoj Kumar Behera, Tapas Ranjan Pradhan and Jangyeswar Sahoo  

Effect of Mansoa alliacea (Bignonaceae) leaf extract on embryonic and tumorigenic mouse cell lines

August 2015

Mansoa alliacea contains high concentrations of chemicals thought to be associated with the suppression of tumor growth. Additionally, this plant has been reported to possess analgesic, anti-fungal, and anti-bacterial properties, thereby providing other potential benefits for cancer patients. Low doses of a water extract of M. alliacea were applied to a cancerous and non-cancerous cell line. Doses between 1.254 to 10.04...

Author(s): Camden M. Towne, Jan F. Dudt, and Durwood B. Ray

Identification of bio-active components in leaf extracts of Aloe vera, Ocimum tenuiflorum (Tulasi) and Tinospora cordifolia (Amrutballi)

July 2015

Plants are an integral part of life in many indigenous communities. Besides, being the source of food, fodder, fuel, etc., the use of plants as herbal medicines in curing several ailments goes parallel with the human civilization. The present study was carried out to identify the bio-active compounds in various leaf extracts of Aloe vera, Ocimum tenuiflorum and Tinospora cordifolia using different phytochemical...

Author(s): Jyoti V. Vastrad, Giridhar Goudar, Shameembanu A. Byadgi, Rajkumari Dhanalaxmi Devi and Rajashri Kotur

Serjania erecta Radlk. improves endothelial function in isolated aortic rings

July 2015

Arterial hypertension presents a high incidence in the population, and it is a chronic degenerative disease. The roots of Serjania erecta Radlk. popularly known as “cipó-cinco-folhas”, are used as a decoction against hypertension. This plant belongs to the Sapindaceae family and is plentiful in the Brazilian swamps. The present study was designed to study the effects of daily intake of S. erecta root...

Author(s): Camila Maschieto, Tiago Bruder-Nascimento, Roberta G. Coelho, Arnildo Pott, Clélia A. Hiruma-Lima, Sandra Cordellini and Juliana I. F. De Gobbi

A new pterocarpan from the leaves of Abrus precatorius L.

July 2015

A pterocarpan, 2,3,4,8-tetramethoxy-6a,11a-dihydro-6H-benzo[4,5]furo[3,2-c]chromene-7,9-diol (compound 1) was isolated from the dichloromethane extract of the leaves of Abrus precatorius L. The structure of the compound was elucidated by detailed spectroscopic analysis such as 1H NMR, 13C NMR, Distortionless Enhancement by Polarisation Transfer (DEPT), Heteronuclear Multiple-Quantum Correlation (HMQC) and Heteronuclear...

Author(s): Catherine N. Malele, Caroline C. Lang’at-Thoruwa, Anastasia N. Guantai and Sumesh C. Chhabra

Anti-acne activity of Achillea ‘Moonshine’ petroleum ether extract

July 2015

Achillea millefolium (yarrow) is a traditionally used plant to treat wounds. The present study was conducted to evaluate the anti-acne activity of Achillea ‘Moonshine’, a hybrid variety of Achillea. The plant was extracted in four solvents- petroleum ether, ethyl acetate, ethanol and water. These extracts were screened for anti-microbial, free radical scavenging, anti-tyrosinase,...

Author(s):   Rahul Shah, Abhishek Patel, Mamta Shah, Bela Peethambaran ,

Hepatoprotective effect of Amaranthus hypochondriacus seed extract on sodium arsenite-induced toxicity in male Wistar rats

July 2015

The hepatoprotective effect and antioxidant activity of ethanol extract of Amaranthus hypochondriacus seed (ESAH) were evaluated in sodium arsenite (SA) treated rats. Animals were divided into eight groups. The first group was used as control, group II was administered SA (2.5 mg/kg body weight). Groups III, IV and V were administered different doses of ESAH (100, 200 or 300 mg/kg b.w., respectively); groups VI, VII and...

Author(s): Pamela Eloho Akin-Idowu, Oyeronke Adunni Odunola, Michael Adedapo Gbadegesin, Ayodeji Oluwaseyi Aduloju, Solomon Aduvienane Owumi and Ayodeji Mathias Adegoke  

Synergistic activity from Hymenaea courbaril L. and Stryphnodendron adstringens (Mart.) Coville against multidrug-resistant bacteria strains

July 2015

Infections caused by multidrug-resistant bacteria are a problem of public health, turning the search for natural products an alternative to antibiotics of great importance. The aim of this study was to investigate the in vitro antimicrobial activities of Hymenaea courbaril and Stryphnodendron adstringens against bacterial clinical isolates. The crude extracts of both vegetal species in study showed bacteriostatic...

Author(s): Álan Alex Aleixo, Vidyleison Neves Camargos, Karina Marjorie Silva Herrera, Ana Cláudia dos Santos Pereira Andrade, Michelli dos Santos, Vívian Correia Miranda, Rafaella Souza Carvalho, Juliana Teixeira de Magalhães, José Carlos de Magalhães, Luciana Alves Rodrigues dos Santos Lima and Jaqueline Maria Siqueira Ferreira  

Anti-arthritic and cytotoxic effects of methanolic extract of Ixora nigricans leaf

July 2015

This study aimed to evaluate anti-arthritic and cytotoxic effects of methanolic extract of Ixora nigricans leaf. Anti-denaturation method was performed by using bovine serum albumin (BSA) to evaluate the anti-arthritic potential. The screening of cytotoxic activity was done using brine shrimp lethality bioassay. The in vitro study on Ixora nigricans leaf showed the presence of significant anti-arthritic activity. Here,...

Author(s): Mohammad Nazmul Alam, Md. Shahrear Biozid, Ahmad Ibtehaz Chowdhury, Muhammad Moin Uddin Mazumdar, Sudipta Chowdhury and Md. Irfan Amin Chowdury

Testicular damage in Wistar rats caused by methanolic extracts of plants from the North of Mexico

July 2015

The aim of this study was to evaluate the effect of methanolic extract of plants from the north of Mexico, on testicular morphology and spermatic quality in Wistar rats. Methanolic extracts were orally administered to 4 experimental groups (n=6) of rat for 30 days; a control group not treated with plant extract was included. All animals were sacrificed 24 h after the last dose. Samples of testicles were...

Author(s): Rubén García Garza, Adolfo Soto Domínguez, Miguel Angel Tellez López, Nadia Denys Betancourt Martínez, Ruben Daniel Arellano Perez-Vertti, Carlos Leyva Orasma, Benjamín Serrano Gallardo and Javier Morán Martínez

Anti-inflammatory property and redox profile of the leaves extract from Morinda citrifolia L.

June 2015

Morinda citrifolia Linn (Rubiaceae), popularly known as noni, is widely used in folk medicine in the form of decoction and infusion, particularly as anti-inflammatory, depurative, anti-rheumatic and antiulcer remedy. The infusion of M. citrifolia L. leaves is used in popular medicine in Northeast of Brazil to treat inflammatory and painful diseases. The present study was designed to evaluate the antioxidant potential...

Author(s): Mairim Russo Serafini, Emiliano de Oliveira Barreto, Fabiola de Almeida Brito, João Paulo Almeida dos Santos, Bruno dos Santos Lima, Cristiani Isabel Banderó Walker, Francilene Amaral da Silva, Lucindo José Quintans-Junior, Daniel Pens Gelain and Adriano Antunes de Souza Araújo

A review of four common medicinal plants used to treat eczema

June 2015

Many medicinal plants are commonly used to treat skin diseases such as eczema, psoriasis, vitiligo, cellulitis, herpes and cancer. Herbal medicine is as old as civilization. Application of traditional herbal medicine is widespread in different regions of the world. It is more common in villages and desert areas where medical services are less accessible. Herbal treatments are generally perceived as effective and have...

Author(s): Shadi T. Zari and Talal A. Zari

Foliar bioactive compounds in Amburana cearensis (Allemao) A.C. Smith seedlings: Increase of biosynthesis using mycorrhizal technology

June 2015

Amburana cearensis (Allemao) A.C. Smith is a widely used legume by the population due to its medicinal properties. This species establish symbiosis with the arbuscular mycorrhizal fungi (AMF) that can increase the production of secondary metabolites, a fact which has not been clarified for this plant. Therefore, the aim of this study was to examine the contribution of the AMF in the production increase of foliar...

Author(s): Paula Tarcila Félix de Oliveira, Gilberto Dias Alves, Francineyde Alves da Silva and Fábio Sérgio Barbosa da Silva,

Effects of the stem barks aqueous extract of Anthocleista schweinfurthii Gilg (Loganiaceae) on acute and chronic gastric ulcers rats models

June 2015

Anthocleista schweinfurthii is used in the traditional management of gastro-duodenal ulcers; this led us to evaluate the gastro-cytoprotective and healing effects of this plant. Anti-ulcer activity of the stem barks aqueous extract of A. schweinfurthii (EAS) was evaluated using five methods: HCl/ethanol; indomethacin-HCl/ethanol; absolute ethanol; pylorus-ligated (acute gastric lesions); and acetic acid-induced chronic...

Author(s): Christophe Mezui, Frida Longo, Paul Tan, Celine Nkenfou, Ntsayo Fokou and Hamani Salou

Potential medicinal application and toxicity evaluation of extracts from bamboo plants

June 2015

Bamboo plants play a significant role in traditional Asian medicine, especially in China and Japan. Biomedical investigations on the health-benefiting effects as well as toxicity of different parts and species of bamboo have been carried out worldwide since the 1960s. This review summarizes the current scientific findings on the biological effects of bamboo-based products, and contrasts these findings with the...

Author(s): Jun Panee

Antiplatelet aggregation and cytotoxic activity of betulinic acid and its acetyl derivative from Melaleuca bracteata

June 2015

Platelet dysfunctions are implicated in cardiovascular diseases. Management of abnormal platelet aggregations with natural products is a promising approach to the treatment of cardiovascular diseases. In this study, betulinic acid (BA) isolated from Melaleuca bracteata leaf extract, and its acetyl derivative (3-β acetylbetulinic acid) (BAA) were investigated for their antiplatelet aggregation and cytotoxic...

Author(s): Foluso O. Osunsanmi, Oluwagbemiga S. Soyingbe, Idiat B. Ogunyinka, Rebamang A. Mosa  Monisola I. Ikhile, J. Catherine Ngila, Francis O. Shode and Andy R. Opoku  

Antituberculous, antimicrobial, cytotoxicity and phytochemical activity study of Piliostigma thonningii extract fractions

June 2015

World Health Organization studies have demonstrated that 80% of the world’s population depends on medicinal plants for their primary health care. This has prompted increased efforts to the adoption and integration of herbal practices in health systems. This study soughts to answer the question whether Piliostigma thonningii has antitubercular, antibacterial, antifungal and cytotoxic activity. Antimicrobial...

Author(s): Sospeter Ngoci Njeru, Meshack Amos Obonyo, Silas Mwaniki Ngari, Samwel Nyambati Onsarigo, John Mwaniki Njeru, and Paul Kuria Kamweru,

Studies on Chemical and Biological properties of Bryonia epigaea (Rottler)

June 2015

To investigate the phytochemical, antimicrobial and antioxidant potentials of Bryonia epigaea (Rottler). The study was performed by using various in-vitro methods such as 1, 1 Diphenyl 2 picryl hydrazyl (DPPH), and Agar well diffusion method for different concentrations of methanolic extracts. Phytochemical constituents of the three extracts (Hexane, Acetone and Methanol) were determined. Total Phenol content was...

Author(s): K. Narendra, J. Swathi, K.M. Sowjanya, K.V.N. Rathnakar Reddi, M. Maruthi Varaprasad, Ch. Padmavathi, G. Venkata Rao and A. Krishna Satya

A review on gall karkatshringi

June 2015

Karkatasringi (Pistacia integerrima) is a well known medicinal plant which belongs to the family of Anacardiaceae. The plant is indigenous to India and is found in the outer ranges of the North-Western Himalayas at an altitude of 500 to 2500 m. The different parts of the plant like leaf, bark, root and galls are reported to contain the secondary metabolites. Among them, the galls are more used in folk medicines. They...

Author(s): Kaur Barinder and Singh Saurabh

Antimicrobial activity and synergistic effects of an ethyl acetate fraction from methanol extract of Myracrodruon urundeuva bark

June 2015

This study aimed to investigate the antimicrobial action of different methanolic extract fractions from Myracrodruon urundeuva (Anacardiaceae) bark and to evaluate the interaction between the most active fraction and some commercial antibiotics. After methanolic extraction, the extract obtained was submitted to liquid/liquid fractionation using cyclohexane, ethyl acetate, n-butanol and water. All fractions showed...

Author(s): Jannyson José Braz Jandú, Luís Cláudio Nascimento da Silva, Márcia Vanusa da Silva and Maria Tereza dos Santos Correia

Refining the methods of extraction and purification of apigenin from Viola yedoensis makino

May 2015

In this study, the effects of supercritical CO2 extraction and macroporous adsorbent resin on separation and purification of apigenin were compared. A better separation and purification macroporous adsorbent resin was selected according to static adsorption and desorption results. Silica gel column chromatography and LSA-10 macroporous adsorbent resin performed better in the separation and purification procedure. The...

Author(s): Ai-wen Dong, Qi Zhuo, Xiao-ying Bu, Shen-hai Zhu and Guo-qing Wang  

Hypoglycemic activity in diabetic rats of stigmasterol and sitosterol-3-O-β-D-glucopyranoside isolated from Pseuderanthemum palatiferum (Nees) Radlk. leaf extract

May 2015

Two major compounds, stigmasterol (ST) and sitosterol-3-O-β-D-glucopyranoside (SG) were isolated from Pseuderanthemum palatiferum leaf extract which is used traditionally as an antidiabetic. ST and SG at doses of 0.25 and 0.50 mg/kg were fed to diabetic rats for 21 days, and the fasting blood glucose (FBG) level and biochemical data on day 0, 4, 7, 10, 14, 17 and 21 were determined and compared with the...

Author(s): Somsak Nualkaew, Peerawit Padee, and Chusri Talubmook

Nutritional and medicinal potential of Grewia subinaequalis DC. (syn. G. asiatica.) (Phalsa)

May 2015

Grewia subinaequalis DC. (syn. G. asiatica) (Phalsa) is a food plant and can also be used as an herbal medicine for the treatment of various diseases. In traditional folklore medicine, the fruit has been used as astringent, stomachic and cooling agent. When unripe, it has been reported to alleviate inflammation and was administered in respiratory, cardiac and blood disorders, as well as in fever. Root and bark has been...

Author(s): Jyoti Sinha, Shalini Purwar, Satya Kumar Chuhan and Gyanendra Rai  

Anticoagulant and anti-inflammatory activity of a triterpene from Protorhus longifolia stem bark

May 2015

This work evaluated the anticoagulant and anti-inflammatory activity of a lanosteryl triterpene (3β-hydroxylanosta-9,24-dien-21-oic acid) isolated from Protorhus longifolia stem bark. Tail bleeding time assay was used to investigate the ex vivo anticoagulant activity. The effect of the triterpene on the thermally induced aggregation of malate dehydrogenase (MDH) and citrate synthase (CS) was studied. The...

Author(s): Rebamang A. Mosa, Thabo Ndwandwe, Nontando F. Cele and Andy R. Opoku  

Evaluation of extract from leaves of Calophyllum brasiliense Cambess. (Clusiaceae) using micronucleus assay in mouse bone-marrow cells

May 2015

This study evaluated the chomosomal damage potential of the extract from leaves of Calophyllum brasiliense Cambess. (Clusiaceae) in mouse bone-marrow cells. The extract was analyzed by high-performance liquid chromatography (HPLC) to assess the concentration of coumarin (-) mammea A/BB, a compound with antileishmanial activity. The chromosomal damage potential of the extract was evaluated by the micronucleus test in...

Author(s): Lilian Lucy dos Santos, Mislaine Adriana Brenzan, Paula Akemi Honda, Roberto Barbosa Bazotte, Carlos Eduardo Oliveira, Mirian Ueda Yamaguchi, Lucia Elaine Ranieri Cortez and Diógenes Aparício Garcia Cortez

The effect of light quality, temperature and substrate on seed germination and epicotyl development of Carapa guianensis, a multi-use neotropical tree

May 2015

The neotropical tree Carapa guianensis has several economic and medicinal applications, and is valued for both the high-quality oil extracted from its seeds and its mahogany-like wood. Recruitment and expansion of C. guianensis depend mainly on sexual reproduction. However, germination conditions for C. guianensis are poorly studied. This makes the understanding of its germination requirements vital for conservation and...

Author(s): Larisse Lobo de Oliveira and Andrea Furtado Macedo,  

Anti-carcinogenic effects of ethanolic extracts from root and shoot of Lupinus angustifolius on breast carcinoma cell lines MCF-7 and BT20

May 2015

The identification of medicinal plants and derived natural products for development as anti-cancer agents is of long standing interest. We have investigated the anti-proliferative properties of Lupinus angustifolius on breast cancer and, in particular, whether the extracts of roots and shoots of L. angustifolius can be considered as candidates for primary and secondary cancer prevention. Ethanolic extracts of roots and...

Author(s): Stapel, J., Oppermann, C., Richter, D. U., Ruth, W. and Briese, V.  

Antioxidant activity, total phenolic and flavonoids contents in Stachytarpheta cayennensis, (Rich.) Vahl. (Verbenaceae)

May 2015

In recent years, a substantial amount of evidence has pointed to the key role of free radicals and other oxidants as the main culprits for aging and degenerative diseases associated with aging, such as cancer, cardiovascular diseases, cataract, decline of the immune system and brain dysfunctions. The objective of this work was therefore to detect variations in total phenol and flavonoid content, and in the antioxidant...

Author(s): Sideney Becker Onofre , Zípora M. Q. Santos, Francini Y. Kagimura and Shaiana P. Mattiello

GC-MS analysis of esterified fatty acids obtained from leaves of wild and cultivated specimens of Leonotis nepetifolia

April 2015

Leonotis nepetifolia (L.) R. Br. is an African bush that belongs to the Lamiaceae family which was introduced as ornamental plant in all the continents. In Brazil, the plant is known as “cordão de são francisco” or “cordão de frade”. The plant has a traditional use in folk medicine for the treatment of some human diseases. In this study, it was realized for the first time,...

Author(s): Ana Paula de Oliveira, Amanda Leite Guimarães, Edigênia Cavalcante da Cruz Araújo, Izabel Cristina Casanova Turatti, Norberto Peporine Lopes and Jackson Roberto Guedes da Silva Almeida  

Flavonoids from the rhizomes of Elephantorrhiza elephantina and Pentanisia prunelloides

April 2015

This paper is reports on the isolation of flavonoid compounds from two medicinal plant species that are widely used in Southern Africa, Elephantorrhiza elephantina and Pentanisia prunelloides which belong to families Fabaceae and Rubiaceae, respectively.  The identification and comparative analysis of flavonoids in E. elephantina and P. prunelloides as well as the structural elucidation of flavonoids were performed...

Author(s): S. J. Mpofu, T. A. M. Msagati and R. W. M. Krause  

Effect of different water regimes and organic manures on indole acetic acid (IAA), oxidase activity, leaf area, light transmission ratio, chlorophyll stability index, relative water content and yield attributes of noni (Morinda citrifolia L.)

April 2015

An experiment was conducted at Horticultural College and Research Institute, Tamil Nadu Agricultural University, Periyakulam in split plot design with irrigation regimes on main plot (four levels) and organic manures on sub plot (eight levels) with two replications. Among the different treatment combinations, M2S4 (100% WRc through drip irrigation + 50% farmyard manure + 50% vermicompost) exhibited superior performance...

Author(s): S. Muthu Kumar and V. Ponnuswami  

Traditional medicinal plants used by Kunama ethnic group in Northern Ethiopia

April 2015

Utilization of medicinal plants is almost as old as the history of mankind. Semi-structured interview, guided field walk, group discussion and market survey were used to collect ethnobotanical data in Tahitay Adiyabo and Kafta Humera districts in northern Ethiopia. A total of 47 informants (30 males and 17 females) were selected purposefully from three sub-districts: Lemlem (n = 27), Adi-Goshu (n = 10) and Hilet-Coca (n...

Author(s): Meaza Gidey, Tadesse Beyene, Maria Adele Signorini, Piero Bruschi and Gidey Yirga

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