Journal of
Medicinal Plants Research

  • Abbreviation: J. Med. Plants Res.
  • Language: English
  • ISSN: 1996-0875
  • DOI: 10.5897/JMPR
  • Start Year: 2007
  • Published Articles: 3654

JMPR Articles

April 2019

Genus Etlingera - A review on chemical composition and antimicrobial activity of essential oils

Essential oil from plants belonging to several species has been extensively used as natural resources in the prevention and treatment of a large number of diseases. The medicinal and aromatic plants of genus Etlingera produces high percentages of essential oil from its every organ and is recommended for a variety of health problems by traditional systems of medicine in south-east Asia. Essential oils from this genus...

Author(s): A. F. M. Shahid Ud-Daula and Mohammad A. Basher

April 2019

Cytotoxic potential of 14 Passiflora species against cancer cells

This work aimed to evaluate the cytotoxic potential against cancer cells of Passiflora genus plant species cultivated in Brazil and identify the mechanism of cytotoxicity induced by the most promising extract. Ethanolic extracts from the leaves of 14 Passiflora species were obtained by accelerated solvent extraction and in vitro cytotoxicity evaluated against cancer cell lines using MTT assay at a single concentration...

Author(s): Ricardo Guimarães Amaral, Silvana Vieira Floresta Gomes, Maria Claudia dos Santos Luciano, Cláudia do Ó Pessoa, Luciana Nalone Andrade, Patrícia Severino, Geraldo Célio Brandão, Larissa Mendes Bomfim, Milena Botelho Pereira Soares, Daniel Pereira Bezerra, Jorge Maurício David and Adriana Andrade Carvalho  

March 2019

Bio-guided identification of antiglycative constituents from the leaves of Mangifera indica L.

Advanced glycation end-products (AGEs) have been shown to be implicated in many degenerative disorders as well as diabetic pathology. Of interest, several natural compounds including phenolic constituents are capable of inhibiting the formation of AGEs. Bio-guided fractionation of a methanol extract from Mangifera indica leaves led to the characterization of six antiglycative constituents including gallic acid (1),...

Author(s): Samba Fama Ndoye, Didier Fraisse, Blandine Akendengué, Rokhaya Sylla Gueye, Cheikh Sall, Mael Gainche, Insa Seck, Catherine Felgines, Matar Seck and François Senejoux  

March 2019

Edraianthus pumilio (Schult.) A. DC.: Phytochemical and biological profile

Edraianthus pumilio is stenoendemic plant native to Dalmatia, Croatia. This paper deals with its phytochemical and biological profile. Phytochemical profile of volatile oil was performed by the gas chromatography–mass spectrometry (GC/MS), while total phenolic content of its aqueous extract was performed by Folin-Ciocalteu method. The phytochemical analysis showed that the main volatile oil compounds were nonanal...

Author(s): Olivera Politeo, Stanislava Talic  and Mirko Ruscic  

March 2019

Protective effects of Pleurotus ostreatus in ameliorating carbon tetrachloride (ccl4) induced liver injury in Wistar rats

Since oxidative stress is implicated in the pathogenesis of liver diseases, this study was carried out to evaluate the hepatoprotective, hematoprotective and hypolipidemic effects of Pleurotus ostreatus (Oyster mushroom) in Carbon Tetrachloride (CCl4) induced liver injury in wistar rats. Thirty rats were used for this study. The rats were divided into five groups of six rats per cage. Group I that served as the normal...

Author(s): Ubhenin, A. E., Adamude F. A., Nweze,C.C., and Dingwoke, E.J.  

March 2019

Identification of annotated metabolites in the extract of Centella asiatica

Plants contribute to 75% of molecular medicines (MM) either directly or indirectly. Centella asiatica (CA) is being extensively used in experimental and clinical studies. However, its scientific approval is not forthcoming. It is well known that every plant contains useful as well as some harmful compounds. Subjecting whole plant extracts containing harmful compounds to modern pharmacological methods will only...

Author(s): Komal Rani, Mitali Tyagi, Akanksha Singh, Vairamani Shanmugam, Annaian Shanmugam, Manoj Pillai and Alagiri Srinivasan,  

February 2019

Essential oil composition, antifungal activity and leaf anatomy of Lippia alba (Verbenaceae) from Brazilian Chaco

This study aims to determine the essential oil chemical composition of Lippia alba (Mill.) N.E.Br. ex Britton & P. Wilson collected in the Brazilian Chaco where plants grow in conditions of high temperatures in the summer, periodic flood, low temperatures and air humidity in the winter. We also evaluate the oil antifungal activity against the animal and plant pathogenic fungi Aspergillus flavus, A. fumigatus, A....

Author(s): Rosani do Carmo de Oliveira Arruda⊃, Cristiane Pimentel Victório⊃, Amanda Galdi Boaretto⊃, Carlos Alexandre Carollo⊃, Cariolando da Silva Farias, Clarice Rossato Marchetti, Ronaldo José dos Santos⊃, Giovana Cristina Giannesi and Denise Brentan Silva⊃  

February 2019

Determination of concentration of some essential and heavy metals in roots of Moringa stenopetala using flame atomic absorption spectroscopy

This study is aimed at determination of concentration of essential (Ca, K, Na and Mg) and heavy (Cd, Cr, Pb, Hg, Cu and Zn) metals using Flame Atomic Absorption Spectroscopy (FAAS) of samples taken from fresh roots of Moringa stenopetala. A wet digestion method involving use of mixture of (HCl and HNO3, ratio 3:1) and 10 ml of 30% H2O2 at an optimum temperature and time duration was deployed during sample preparations....

Author(s): Tsegaye Mega Kaba and Kusse Gudishe Goroya  

February 2019

Aristolochic acids in herbal medicine: Public health concerns for consumption and poor regulation of botanical products in Nigeria and West Africa

Aristolochic acids are naturally occurring biomolecules found in plants of the genus Aristolochia and Asarum belonging to the family Aristolochiaceae. They are reported to be carcinogenic and nephrotoxic; and are implicated in kidney diseases, aristolochic acid nephropathy (AAN) which may result in kidney failure, other health complications and possibly death. Aristolochic acids are highly genotoxic and are linked to...

Author(s): Okhale S. E., Egharevba H. O., Okpara O. J., Ugbabe G. E., Ibrahim J. A., Fatokum O. T., Sulyman A. O.  and Igoli J. O.  

February 2019

In vitro effect and scanning electron microscopic changes of Nigella sativa loaded chitosan nanoparticles on Schistosoma mansoni adult

Nanoparticles can act as drug carriers that can modulate pharmacokinetics, increase bioavailability and target release with minimal toxic effects. The present work aimed to assess the therapeutic effect and electron microscopic changes of Nigella sativa loaded Chitosan Nanoparticles (NSLCN) on adult Schistosoma mansoni in vitro. Adult worms were removed from the portal and mesenteric veins of infected mice after 90...

Author(s): Shereen Magdy Kishik, Ahlam Farag Mohram, Marwa Mohamed Nagib, Hemat Salah Ali and Fatma Fawzi Hendawy  

February 2019

Effect of hormones on the seed germination of Bupleurum species

In Asia, Radix Bupleuri (Bupleurum spp. root) is an important medicine used for treating many diseases over the past 2000 years. However, its cultivation is difficult due to poor germination rates and loss of seedling viability shortly after seeding. In the present study, the effect of 6-benzyl aminopurine (6-BA), daminozide, gibberellin (GA3), paclobutrazol, uniconazole, and mepiquat chloride (MC) on the germination of...

Author(s): Ma Yu, Guihua Lv, Hongzhang, Yuchan Li, Cheng Yuan, Zhikang Tang, Xiaoyan Shu, Chun Sui, Dabin Hou and Jian-He Wei  

January 2019

Exploring the anticoagulant and antiplatelet effect of the extracts of the red marine alga Acanthophora spicifera

Cardiovascular diseases represent the major cause of death and morbidity in the world. An uncontrolled activation of the coagulation cascade and platelet aggregation may lead to the formation of thrombi. Antithrombotic drugs have limitations and may produce side effects, and consequently, alternative therapies have been extensively investigated. Thus, the aim of this work was to evaluate anticoagulant and antiplatelet...

Author(s): Vivian Rodrigues de Souza, Laura de Andrade Moura, Ana Cláudia Rodrigues da Silva, Kelly Ketely Granja Pereira, Caio Cesar Richter Nogueira, Diana Negrão Cavalcanti, Valéria Laneuville Teixeira and André Lopes Fuly  

January 2019

Antibacterial potential of extracts of the roots of Zingiber officinale against bacterial strains commonly associated with nosocomial infections

Zingiber officinale, commonly known as ginger, has been used as a medicinal plant for decades for medical and culinary purposes. This study aimed to determine the antimicrobial potential of ginger root extracts using the Kirby-Bayer agar diffusion method to compare the zones of inhibition of the extracts to those of synthetic antibiotics against five clinical bacterial pathogens (Escherichia coli, Pseudomonas...

Author(s): Hannaty Abuga and Goabaone Gaobotse  

January 2019

Ethnobotanical study on medicinal plants used by indigenous people in Tenta District, South Wollo, Ethiopia

Ethnobotanical study on medicinal plants was conducted in Tenta District, South Wollo, Ethiopia from December 2016 to May 2017. Data were collected using guided field walk, semi-structured interview, group discussion and direct field observation. Data were analysed using descriptive statistics and response compared with chi-square test. The results documented 121 species of medicinal plants under 98 genera and 53...

Author(s): Tibebu Tefera and Mesele Yihune  

January 2019

Protective potential of Avena sativa seed mucilaginous extract against hyperlipidemia indicated by improved biomarkers and histopathology

Hyperlipidemia is one of the major health concerns worldwide. The present study aimed at utilizing clinicopathological tools to investigate the possible improving effect of Avena sativa mucilaginous extract (ASE) on lipid metabolic and liver function profiles in albino rats. The rats were rendered hyperlipidemic by 6-week supplementation of high-fat diet ad libitum. The rats were grouped into seven groups; with...

Author(s): Ibtsam M. Gheith, and Abubakr M. El-Mahmoudy  

January 2019

Assessment of antioxidant and antidiabetic properties of Picralima nitida seed extracts

The study investigated the antioxidant potential as well as the inhibitory potential of the seed extracts of Picralima nitida on α-amylase and α-glucosidase enzymes. The methanolic, aqueous and coconut water extracts were obtained using 70% methanol, distilled water and coconut water, respectively. Antioxidant properties were studied in vitro using DPPH (1, 1-diphenyl-2-pricrylhydrazyl) radical scavenging,...

Author(s): Akinwunmi Kemi Feyisayo and Amadi Chizi Victor  

January 2019

Utilization, cultivation practice and economic role of medicinal plants in Debre Markos Town, East Gojjam Zone, Amhara Region, Ethiopia

Medicinal plants are useful for primary healthcare as a remedy for diseases and injury, while they are also used traditionally as food and beverages. Despite the wide role of medicinal plant, traditional utilization and management practices are not well documented in Debre Markos Town. Thus, this study was conducted to assess utilization and cultivation practice of the medicinal plants and to identify commonly used...

Author(s): Yebirzaf Yeshiwas, Esubalew Tadele and Mahlet Workie  

December 2018

Medicinal plant use and conservation practices by communities in the Togo Plateau Forest Reserve, Ghana

The use of plants for medicine has constituted an important aspect of primary healthcare delivery system of people throughout the world for many centuries. Nonetheless, information on medicinal plants and their conservation are still lacking in some areas, including the Togo Plateau Forest Reserve in Ghana. This paper investigates the ethnobotany of the Togo Plateau Forest Reserve, Ghana, to document the traditional...

Author(s): Gilchrist K. Faith Dogor, Ruby A. Nyarko, Alexander K. Anning and Alfred  Oteng-Yeboah

December 2018

Evaluation of cytotoxic and antitumor activity of perillaldehyde 1,2-epoxide

The study aimed to evaluate cytotoxicity and antitumor activity of perillaldehyde 1,2-epoxide (PE), a p-menthane monoterpene derivative against four human tumor cell lines ovarian cancer (OVCAR-8), colon carcinoma (HCT-116), glioblastoma (SF-295) and leukemia (HL-60) using the colorimetric MTT assay. PE showed a high degree of inhibition of cell proliferation (GI = 95.66 to 99.71%) and IC50 16.14 μM (± 1.86),...

Author(s): Luciana Nalone Andrade, Patrícia Severino, Ricardo Guimarães Amaral, Grace Anne Azevedo Dória, Andressa da Silva, Melina Alves, Ricardo Luiz Cavalcante Albuquerque Júnior, Maria Claudia Santos Luciano, Cláudia Ó Pessoa, Adriana Andrade Carvalho and  Damião Pergentino de Sousa  

December 2018

Diversity and use of wild edible plants by migratory shepherds in the Himachal Pradesh of the Western Himalayas, India

The present study was carried out in Himachal Pradesh of the Western Himalayas, India to obtain information on the wild edible plants used by the migratory shepherds. The shepherds started their migration in July from Chitkul, Rakchham, Batseri, Sangla and Kamru of district Kinnaur (Himachal Pradesh). Questionnaire for the survey, personal field visits and participatory observations were used to collect information...

Author(s): Radha, Sunil Puri and Sanjeev Kumar  

December 2018

Ethnobotanical study of indigenous knowledge on medicinal plants used to treat diseases in selected districts of Amhara Regional State, Ethiopia

This study was conducted in four districts of Amhara Region, Ethiopia. The aim of the study was to assess medicinal plants found in Menz gera, Siyadebirna Wayu, Antsokiya gemza and Bugna districts, Amhara region, Ethiopia. The ethnobotanical surveys were carried out from September 2017 to June 2018 using a semi-structured checklist consisting of questions or issues prepared in advance. Two separate questionnaires were...

Author(s): Tewodros Kelemu and Worku Wolde  

December 2018

Selenium-enriched polysaccharides from pyracantha fortuneana (Se-PFPs) augment docetaxel-induced tumor suppression in human ovarian cancer

Pyracantha fortuneana (Maxim.) contains many healthy ingredients, including selenium-enriched polysaccharides. Selenium-enriched polysaccharides from P. fortuneana (Se-PFPs) have anti-mutation and anti-oxidation activities, along with anti-tumor activity in ovarian cancer and breast cancer cells. Docetaxel (DTX) is widely applied in therapeutic treatment for ovarian cancer. However, its use in clinics is restricted due...

Author(s): Zhengtai Liu, Liyue Gai, Jiayuan Qu, Chong Guo, Yuwen Zhao, Yu Yang, Xiaoyue Wen and Chengfu Yuan

December 2018

Comparative analysis of capsaicin in twenty nine varieties of unexplored Capsicum and its antimicrobial activity against bacterial and fungal pathogens

In this study, the capsaicin content of chile pepper extracts from 29 unexplored varieties of Capsicum (twenty five varieties of Capsicum chinense and five of Capsicum annuum) was quantified and correlated with the antimicrobial potential against bacterial and fungal pathogens. The capsaicin content and bactericidal activity against numerous human pathogens (Salmonella, Escherichia coli O157:H7, Listeria monocytogenes,...

Author(s): Morrine A. Omolo, Zen-Zi Wong, Weih G. Borh, Grant A. Hedblom, Kamal Dev, and David J. Baumler,  

December 2018

Hepato-protective potentials of Sterculia setigera stem-bark extract on acetominophen induced hepato toxicity in Wistar albino rats

The study was set to investigate the potency of stem bark extract of Sterculia setigera as a hepato-protective agent against acute administration (overdose) of acetaminophen in experimental animals. Experimental animals were grouped into six treatments with each group containing five rats. Group 1 was the placebo, Group II was the standard treatment orally administered acetaminophen at a dosage of 250 mg/kgbw and...

Author(s): Garba M. H., Sherifat M. L., Abdul-Majeed A. O., Hafsa L. M., Awal A.B., Sa’adu A. A. and Lekene B. J.  

December 2018

Phytochemical analysis, antioxidant, antibacterial and combinational effects of medicinal plants used by Bapedi traditional healers to prepare herbal mixtures

The aim of this study is to evaluate the biological activities of some plant species used in the preparation of herbal mixtures and determine the combinational effects. The plant materials were collected from traders who use them to prepare herbal mixtures claimed to be blood purifiers, pain-relievers, anti-diarrheal and aphrodisiac medicines. An aqueous decoction of each plant species was prepared. Thin layer...

Author(s): Mashilo Mash Matotoka and Peter Masoko  

November 2018

In vivo efficacy of Dialium guineense fruit pulp on hemeoxygenase-1 and angiotensin converting enzyme in experimental diabetes

The study aims to investigate the effect of aqueous fruit pulp of Dialium guineense on hemeoxygenase, and insulin release, inhibition of angiotensin converting enzyme (ACE) and possible hypoglycemia in streptozotocin-induced diabetic rats. Twenty four male Wistar rats were grouped into control, diabetic (Dm), diabetic + 300 mg/kg body weight Dialium guineese (Dm+ DG) and diabetic + 100 mg/kg metformin (Dm +MET). Apart...

Author(s): Etah E. Nkanu, Gabriel Ujong, Victoria Okon and Iya Eze Bassey  

November 2018

Evaluation of the phytochemical composition, antimicrobial and anti-radical activities of Mitracarpus scaber (Rubiaceae)

Mitracarpus scaber is a medicinal plant used in traditional practices for the treatment of dermatoses and liver diseases. The objective of this study was to quantify the content of phenolic compounds and to evaluate the anti-radical and antimicrobial activities of four types of its total extracts on ten microbial strains. The Folin-Ciocalteu method was used to determine total phenol content, condensed tannin content by...

Author(s): Ouadja B., Anani K., Djeri B., Ameyapoh Y.O. and Karou D. S.  

November 2018

Bio-guided anti-cariogenic and phytochemical valorization of Guiera senegalensis and Pseudocedrela kotschyi stem extracts

The objective of the present study is to carry out bio-guided phytochemical investigation of Guiera senegalensis and Pseudocedrela kotschyi stem extracts. The two plants are used as toothpicks for oral hygiene. The inhibition test revealed a bacteriostatic effect of hexane extract PK1 of P. kotschyi against Streptococcus mutans ATCC 25175 and Streptococcus salivarius ATCC 20560, two bacterial cariogenic strains, with a...

Author(s): Guessan Bi Goblé Landry, , Kadja Amani Brice, Cottet Kevin, Lecouvey Marc, Mamyrbékova-Békro Janat Akhanovna and Békro Yves-Alain  

November 2018

Evaluation of herbal cocktail used in the treatment of malaria on liver tissue of adult Wistar rats

Interest is renewed in herbal medicine since it is believed it has less side effects and is safer. In addition, there has been continued demand to obtain more drugs from plant sources to alleviate various ailments of mankind. This study is aimed at investigating the antimalarial activity in an herbal cocktail and individual plant extracts contained on Plasmodium berghei in infected Wistar rats. Thirty five Wistar rats...

Author(s): Moronkeji Akinpelu, Eze Ikechi Gerald, Bejide Ronald Ayodele, Anwara Ogbonnaya Akpu and Igunbor Michael Chuks  

November 2018

Effect of aqueous extract of Ocimum gratissimum on acetaminophen induced renal toxicity in male wistar rats

The need for an alternative means of managing renal toxicity has become necessary instead of kidney transplant. This study investigated the effect of aqueous extract of Ocimum gratissimum (AEOG) on acetaminophen (ACE) induced renal toxicity. Twenty-five male Wistar rats were assigned into five groups (1, 2, 3, 4, and 5) with five rats in each group. Group 1 served as the normal control and received normal saline as...

Author(s): Okerulu Linda, Celestine Ani, Choice Nworgu, Igwe Uzoma, Ugwuishi Emeka and Nwachukwu Daniel  

November 2018

A review on the botanical aspects, phytochemical contents and pharmacological activities of Warburgia ugandensis

Warburgia ugandensis Sprague (Family Canellacea) commonly known as Ugandan greenheart or pepper bark tree, is a highly valued medicinal plant in traditional medicine with a broad spectrum of antimicrobial activity whose parts especially the leaves and stem bark have for long been used in the treatment and management of many diseases and health conditions such as stomachache, cough, toothache, fever, malaria, oral...

Author(s): Denis Okello, , , Richard Komakech, , Motlalepula Gilbert Matsabisa and Youngmin Kang,  

November 2018

Antibacterial and antioxidant potential of Albizia anthelmintica as a medicinal plant on pathogenic veterinary isolates

Albizia anthelmintica is a medicinal plant belonging to the Fabaceae family. It is widely used by smallholder farmers and pastoralists to treat internal parasites in their livestock. This study aimed to determine the antibacterial and antioxidant potential of A. anthelmintica on pathogenic veterinary isolates. 100% hexane (He100), 100% chloroform (Ch100), 100% ethanol (E100), and 70% ethanol (E70) extracts of the roots...

Author(s): Kabo Wale, Tebogo Elvis Kwape, Laurah Sethibe, Goabaone Gaobotse, Daniel Loeto and Bongani Sethebe

November 2018

In vitro antibacterial and antidiarraheic activity of root bark extract of Anogeissus leiocarpa (Combretaceae) during an experimental bacterial diarrhea induced by Escherichia coli extended-spectrum β-lactamases (ESBL) in albino Wistar rats

The present study was conducted to investigate in vitro and in vivo antibacterial activity of the root bark extracts of Anogeissus leiocarpa (DC) Guill. & Perr, in Escherichia coli extended-spectrum β-lactamases (ESBL)-induced diarrhea in rat. The antibacterial activity was performed in vitro by determining the inhibition zone using standard agar diffusion method as well as in vivo on E. coli infected Wistar...

Author(s): Kouangbé Mani Adrien, Sonan Kouadio Henri Guillaume, Méité Souleymane, Boga Gogo Lucien and N’Guessan Jean David  

November 2018

Antioxidant and antiproliferative activities of ethanolic extracts of Elateriospermum tapos Blume (Euphorbiaceae)

Phytochemicals possessing free radical scavenging and antiproliferative activities play an important role in cancer chemoprevention. In this study, the ethanolic extracts prepared from fresh and dried leaves, bark, and seed skin of Pra (Elateriospermum tapos Blume.) were tested for their antioxidant activity using a ferric reducing ability of plasma (FRAP) assay. The antiproliferative activities against four human...

Author(s): Sita Tisadondilok, Thanaset Senawong, Prasan Swatsitang and Auamporn Rattanasing  

October 2018

In vivo antitumor effect of the aqueous extract of Punica granatum in the sarcoma 180 murine model

Punica granatum, specifically the fruit, has a long ethno medical history and is a phytochemical reservoir of great medicinal value. The phytochemistry and pharmacological actions of all P. granatum components suggest a wide range of clinical applications. The aim of the present study is to investigate the anticancer potential of aqueous extract of P. granatum (AEPG) in experimental models. The chemical composition of...

Author(s): Talita Santos Bastos, Danilo Barauna Nascimento da Costa, Rafael Barreto Vieira Valois, Sara Maria Thomazzi, Marismar Fernandes do Nascimento, Grace Anne Azevedo Dória, Ricardo Guimarães Amaral, Silvana Vieira Floresta Gomes, Isabel Bezerra Lima-Verde, Cláudia Andréa Lima Cardoso, Francine Ferreira Padilha, Margarete Zanardo Gomes, Juliana Cordeiro Cardoso, Adriana Andrade Carvalho andRicardo Luiz Cavalcanti de Albuquerque-Júnior,   

October 2018

Effects of methanolic calyx extract of Hibiscus sabdariffa on body weight, blood cholesterol and liver marker enzymes in Wistar rats

Eighty male albino rats were used to investigate the effects of methanolic calyx extract of Hibiscus sabdariffa on body weight, blood cholesterol and liver enzymes markers. Twenty-eight days oral administration of 100, 200, 400 and 800 mg/kg body weight of the extract showed a significant (p<0.05) time-dependent decrease in the body weights of all the treated groups when compared with the control, with 100 mg/kg...

Author(s): Emmanuel I. Nnamonu, Vincent C. Ejere, Edmund C. Mbegbu, Chiemekam S. Ezechukwu and Anthony O. Ejim  

October 2018

Knowledge of medicinal plants used by residents in two peripheral districts of Boa Vista, Roraima, Northern Brazilian Amazon: Phytotherapy as a new strategy in collective health

The aim of the study was to describe local knowledge about the use of medicinal plants cited by study participants, as well as to examine how phytotherapy serves as an important strategy of integrative and complementary practice in coping with health problems. The research is characterized as an exploratory study of the descriptive type. Non-probabilistic snowball sampling generated a sample of one hundred and ten...

Author(s): Kristiane Alves Araújo, Ires Paula de Andrade Miranda, Calvino Camargo and Maxim Repetto  

October 2018

Antiviral effect of the seaweed Osmundaria obtusiloba against the Zika virus

Zika virus (ZIKV), a mosquito-borne member of the family Flaviviridae, is a human pathogen of global significance. Recently, ZIKV, has become a public health problem with increases in numbers of cases and a strong association between ZIKV outbreaks and the spread of cases of Guillain-Barré Syndrome and microcephaly. In this study, the extracts of the seaweed Osmundaria obtusiloba (O. obtusiloba) (native to the...

Author(s): Claudio Cesar Cirne-Santos, Caroline de Souza Barros, , Caio Cesar Richter Nogueira, Leonardo dos Santos Corrêa Amorim, Renata de Mendonça Campos, Norman Arthur Ratcliffe, Valeria Laneuville Teixeira, Davis Fernandes Ferreira and Izabel Christina Nunes de Palmer Paixão  

October 2018

Malaria parasite clearance rate of crude methanol extract of Cryptolepis sanguinolenta in mice infected with chloroquine sensitive strain of Plasmodium berghei

This study aims to determine the malaria parasite clearance rate of crude methanol extract of Cryptolepis sanguinolenta in mice infected with chloroquine sensitive strain of Plasmodium berghei. P. berghei was injected in mice and left for 3 days for establishment. Blood sample collected and diluted with phosphate buffer saline was used for infection. Five (5) groups of animals (mice) were used in this study each...

Author(s): Eze, Chinelo C., Attama, Anthony A., Ibezim, Emmanuel C., Berebon, Dinebari P. and Agbo, Martina C.

October 2018

Chemical composition, oviposition deterrent and larvicidal activities of the wood extracts of Tabebuia avellanedae from the Cerrado of Brazil

Tabebuia avellanedae is an important timber source belonging to the family of Bignoniaceae. The latter is known for its richness in terms of variety of bioactive chemical constituents, and it has been used in folk medicine for treatment of various diseases. The aim of this work was to investigate the chemical composition, oviposition deterrent and larvicidal activities of the wood extracts of T. avellanedae from the...

Author(s): Jaqueline Cibene Moreira Borges, Eder Alves Pereira e Silva, Tarcísio Castro Alves de Barros, Ilsamar Mendes Soares, Sérgio Donizeti Ascêncio, Rodrigo Ribeiro Fidelis and Raimundo Wagner de Souza Aguiar  

September 2018

Antioxidant activity of extracts from Schinus molle L. and Gleditsia triacanthos L.

Methanolic and chloroform extracts obtained from various parts of Schinus molle and Gleditsia triacanthos were evaluated by DPPH radical scavenging assay. The methanolic extracts from S. molle showed scavenging activity ranging from 35.97±1.02 to 83.38±2.74%, while the chloroform seed extract showed relatively weak scavenging activity ranging from 8.20±1.02 to 68.82±3.17%. The IC50 values of...

Author(s): Manoharan Karuppiah Pillai, Kemelo Sanett Matela, Mosotho Joseph George and Sibusisiwe Magama  

September 2018

Medicinal plants used for the management of hepatic ailments in Katsina State, Nigeria

People in Katsina State, Nigeria have been using medicinal plants to cure several ailments associated with liver since time immemorial; however the use of such plants was never documented. In this study, an ethnobotanical survey was conducted to document the medicinal plants used for the management of hepatic ailments in Katsina State, Nigeria. A semi-structured questionnaire method was adopted to interview 150...

Author(s): Sulaiman Sani Kankara, Abdulazeez Bashir Isah, Abubakar Bello, Abdulhamid Ahmed and Umar Lawal  

September 2018

Evaluation of anti-Mycobacterium tuberculosis activity of fractions from selected medicinal plants used traditionally for treating cough and respiratory disorders in South West of Nigeria

Tuberculosis is a contagious airborne infection that mostly affects the lungs. The causative agent of tuberculosis in human is Mycobacterium tuberculosis. The emergence and dissemination of M. tuberculosis isolates that are resistant to multiple antimicrobial drugs represent a growing public health threat. Fractions from Alafia barteri, Chasmanthera dependence, Chrysophyllum albidum, Emilia coccinea, Mezoneuron...

Author(s): Morufu Adisa Ademoye, Labunmi Lajide, Bodunde Joseph Owolabi, and Catherine Chizoba Onubogu

September 2018

A comparative study of the histopathological modifications of adrenal gland in STZ-induced diabetic Wistar rats administered with selected herbal plants versus Glimepiride

This study investigated the comparative study of four herbal extract versus Glimepiride on the histomorphological modification of adrenal gland in STZ induced diabetic rats with a view to understanding their antidiabetic properties.  Forty- two healthy adult Wistar rats (Rattus novergicus) with an average weight of 153.4 g were randomly divided into seven groups (n=6). STZ (65 mg/kg) dissolved in citrate buffer was...

Author(s): Komolafe Omobola A., Ofusori David A., Odukoya Samson A., Saka Olusola S. and Arayombo Babatunde E.

September 2018

Anti-oxidant and anti-microbial study of Adiantum capillus veneris and Pteris quadriureta L

Adiantum capillus veneris (ACV) and Pteris quadriureta (PQ), two common ferns belonging to Pteridophyta family, has been used in traditional Ayurvedic and Unani medicine against numerous human ailments since ancient times. This study was designed to analyse the presence of various phytochemicals in the ACV and PQ leaves and their pharmacological activities. The methanol extract of ACV and PQ leaves was screened for the...

Author(s): Satabdi Rautray, Sukanya Panikar, Asaithambi Sofia and A. Usha Rajananthini    

August 2018

Evaluation of antiplasmodial potential of Aloe barbadensis and Allium sativum on plasmodium berghei-infected mice

A significant percentage of the developing countries are living in malaria-endemic communities and are prone to contacting the disease. The fight against malaria is faced with the occurrence of widespread resistance of Plasmodium falciparum to the available anti-malarial drugs. Thus, this study evaluates the anti-malarial activity of extracts of Aloe barbadensis and Allium sativum in Plasmodium berghei infected mice. To...

Author(s): Nassar Sulaiman Adebayo and Oyewole Motunrayo  

August 2018

Medicine bottled (garrafada): Rescue of the popular knowledge

Using plants to treat health problems is an ancient practice that is still practiced today. One way that plants are used to improve health is through medicine bottled (garrafada). A medicine bottled is a homemade mixture of medicinal plants added to a solvent. Medicines bottled are medicinal mixtures that have been widely used, especially by residents of rural areas. Therefore, the goal of this study was to determine...

Author(s): Graciela da Silva Miguéis, Rosa Helena da Silva, Germano Guarim-Neto and Geraldo Alves Damasceno Júnior  

August 2018

Comparison of several hydrophilic extracts of Polypodium leucotomos reveals different antioxidant moieties and photoprotective effects in vitro

Oral photoprotection can be used to prevent photocarcinogenesis and photoaging. It is mainly based on the presence of antioxidant moieties in phytochemical extracts. The appearance of different botanical formulations endowed with apparently similar properties requires their side-by-side examination using an unbiased approach. The objectives of this study were to determine the antioxidant properties of several extracts...

Author(s): Salvador González, Silvia R Lucena, Pablo Delgado and Angeles Juarranz  

August 2018

Ethnobotanical study of medicinal plants used by local people in Menz Gera Midir District, North Shewa Zone, Amhara Regional State, Ethiopia

This study was conducted in Menz Gera Midir (Ethiopia) to document medicinal plants and related indigenous knowledge of local people. Data were collected from 72 (12 of them key) informants using semi-structured interview, group discussion and guided field walk. Priority ranking, paired comparison and direct matrix ranking were used in data analysis. A total of 155 medicinal plant species, 104 (67.1%) from natural...

Author(s): Seble W. Yohannis, Zemede Asfaw and Ensermu Kelbessa  

August 2018

Evaluating the antipyretic activities of aqueous and ethanol extracts of leaves of Artemisia Annua in mice

Phytomedicines obtained from herbal sources are in great demand as they are able to cure many infectious diseases. Artemisia annua is an herbaceous plant that belongs to Composite family. As traditional medicine, it is used for cancer, ulcer, rheumatic pain and other ailments including fever in children. The objective of the present study was to evaluate the antipyretic activities of the aqueous and ethanol extracts of...

Author(s): Kassahun Dires Ayenew and Teklit Baraki Kebede  

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