Journal of
Medicinal Plants Research

  • Abbreviation: J. Med. Plants Res.
  • Language: English
  • ISSN: 1996-0875
  • DOI: 10.5897/JMPR
  • Start Year: 2007
  • Published Articles: 3631

JMPR Articles

July 2017

In-ovo biological activities of Phyllanthus amarus leaf extracts against Newcastle disease virus

Newcastle disease virus is a paramyxovirus which causes Newcastle disease in birds. Investigation was done on the effect of leaf extract of Phyllanthus amarus against Newcastle disease virus (NDV) using an in-ovo assay. Nine to eleven day-old viable embryonated chicken eggs (ECE) were used for the assay, these were divided into six groups of six eggs each. Methanol, aqueous and n-hexane extracts of the plant leaves were...

Author(s): Faeji, C. O., Oladunmoye, M. K., Adebayo, I. A. and Adebolu, T. T.

July 2017

Evaluation of essential oils for preventive or curative management of melon gummy stem blight and plant toxicity

Melon cultivation is frequently heavily reliant on synthetic fungicides, including products used to control gummy stem blight caused by Stagonosporopsis cucurbitacearum. The essential oils used in controlling plant pathogens may offer an alternative to chemical pesticides. This study evaluated the effectiveness of essential oils to control the gummy stem blight in melon plants. In vitro tests were carried out using...

Author(s): Mateus Sunti Dalcin, Adalberto Corrêa Café-Filho, Renato de Almeida Sarmento, Ildon Rodrigues do Nascimento, Talita Pereira de Souza Ferreira, Raimundo Wagner de Sousa Aguiar and Gil Rodrigues dos Santos

July 2017

Ethnobotanical importance and herbal medicine in Vindhya region of Eastern Uttar Pradesh, India

Vindhya region is one of the less studied areas and characterized for rich vegetations of India. The plants species observed in the area have immense potential for the management and treatment of various ailments. The present paper reports to the documentation and conservation of ethnomedicinal plants of Sonebhadra district and their socio- economic relationship with the forest and its resources. The ethnobotanical data...

Author(s): Dharm Narayan and Pramod Kumar Singh

July 2017

Antibacterial activity of extracts of Stevia rebaudiana Bertoni against Staphylococcus aureus, Staphylococcus epidermidis and Pseudomonas aeruginosa

Plants have been an important source of secondary metabolites known for their diverse biological activities; some have been shown to inhibit the development of certain pathogenic microorganisms. Herein, the antimicrobial activity of the carbon tetrachloride, hexane, ethanol, and aqueous extracts of leaves of Stevia rebaudiana Bertoni against Staphylococcus aureus (strain 921), Staphylococcus epidermidis (strains 965,...

Author(s): Mariana Miranda-Arámbula, Maricruz Olvera-Alvarado, Marta Lobo-Sánchez, Ivonne Pérez-Xochipa, Ada María Ríos-Cortés and Sandra Luz Cabrera-Hilerio

June 2017

Malva neglecta: A natural inhibitor of bacterial growth and biofilm formation

Malva neglecta, a wild plant that grows in different parts of Lebanon, was noted by residents to have soothing effects if taken during episodes of respiratory tract infections. This study was designed to test for the ability of this plant to inhibit bacterial growth and biofilm formation of clinical bacterial isolates. The results showed that while the aqueous extract of the leaves of the plant did not show any...

Author(s): Elias Keyrouz, Patrick Abou Raji El Feghali, Mohammad Jaafar and Tarek Nawas

June 2017

Comparative effect of Nauclea latifolia leaf fractions on blood glucose and lipid profile parameters of alloxan induced-diabetic rats

The antidiabetic effects of methanol, N-hexane and ethyl acetate leaf fractions of Nauclea latifolia were investigated in diabetic model rats. 150 and 300mg/kg fractions of N. latifolia were administered orally to the experimental animals at two weeks interval, while their blood glucose levels were taken daily. At the end of the experiment, their lipid profiles were assayed using standard methods. The research data...

Author(s): Grace Sylvester Effiong and Grace Emmanuel Essien

June 2017

Antiproliferative and pro-apoptotic effects of Andean berry juice (Vaccinium meridionale Swartz) on human colon adenocarcinoma SW480 cells

Vaccium meridionale Swartz, commonly Andean Berry, has a high content of several phytochemicals, such as anthocyanins, phenolic acids, and other flavonoids. However, in spite of its antioxidant capacity, there is little information about its anticarcinogenic properties. This study evaluated the antiproliferative and pro-apoptotic activity of Andean Berry Juice (ABJ) on human colon adenocarcinoma SW480...

Author(s): Carlos Daniel Agudelo, Sandra Arango, Fabián Cortés-Mancera, Benjamín Rojano and Maria Elena Maldonado

June 2017

Identification of Campsis Flos and its common adulterants using ITS2 sequence of DNA molecular barcoding

Internal transcribed spacer 2 (ITS2) is known as a good sequence of DNA molecular barcoding. In this study, the authors authenticated Campsis Flos and its common adulterants based on ITS2 sequence. Campsis Flos has been used in traditional Chinese medicine for many years as a blood activator to promote menstruation. Among its adulterants in the market, the most common are the flowers of Paulownia tomentosa, Hibiscus...

Author(s): Ye Lu, Baoling Ju, Liang Gao and Jin Wang

June 2017

Comparative studies on the possible antioxidant properties of ethanolic seed extracts of Cola nitida (kola nut) and Garcinia kola (bitter kola) on hydrogen peroxide induced oxidative stress in rats

Oxidative stress and impaired antioxidant system have been implicated in the pathophysiology of diverse disease states. This research was done to investigate comparatively the possible enzymatic and non-enzymatic antioxidant properties of ethanol extracts of Cola nitida and Garcinia kola in H2O2-challenged rats. Thirty (30) Wistar albino rats were used for this study and were divided into 6 groups of 5 rats per group....

Author(s): Joshua P. E, Ukegbu C. Y, Eze C. S, Umeh B. O, Oparandu L. U, Okafor J. O, Nkwocha, C and Ogara A.

June 2017

Application of a degreasing process and sequential ultrasound-assisted extraction to obtain phenolic compounds and elucidate of the potential antioxidant of Siparuna guianensis Aublet

This study investigated appropriate means to determine the total phenolic content and antioxidant activity of the leaves of Siparuna guianensis. Evaluation by thin layer chromatography (TLC) revealed phenolic compounds in all extracts. The results were confirmed by high-performance liquid chromatography (HPLC), with the identification and quantification of catechin, epigallocatechin gallate and rutin. The methanolic...

Author(s): Ilsamar Mendes Soares, Maria de Fátima Ribeiro, Odelio Joaquim da Costa, Éber Eurípedes de Souza, Aline Aires Aguiar, Robson dos Santos Barbosa, Tarso da Costa Alvim, Sérgio Donizeti Ascêncio and Raimundo Wagner de Souza Aguiar

May 2017

Phytochemical and acute toxicity studies of methanolic extracts of selected antimalarial plants of Nupeland, north central Nigeria

Malaria remains one of the most prevalent diseases throughout tropics and subtropical areas and its effective chemotherapy remains a problem. Hence the need to continue to explore plants for their therapeutic potentials. In Nupeland, Lannea barteri (monkey’s faru), Piliostigma thonningii (camel’s foot tree or monkey’s bread), Clerodendrum aculeatum (haggar bush or garden quinine) and Crateva adansonii...

Author(s): Usman Idris Nda-Umar, Mohammed Gbate, Abdulkadir Nda Umar, Yahaya Masaga Alfa and Abdullahi Mann

May 2017

Gas chromatography mass spectrometry/Fourier transform infrared (GC-MS/FTIR) spectral analyses of Tithonia diversifolia (Hemsl.) A. Gray leaves

Medicinal plants and its products remain the best therapeutic agents for the management of diseases and infections that affect the health of man. Owing to the recorded ethnomedicinal potentials of Tithonia diversifolia (Hemsl.) A. Gray, this study was aimed at investigating the gas chromatography combined with mass spectrometry (GC-MS) and Fourier transform infrared (FT-IR) spectral analyses of methanolic extract of...

Author(s): Okereke Stanley C., Arunsi Uche O, Nosiri Chidi I and Nwadike Constance

May 2017

Ethnobotanical survey on distribution of medicinal plants in the genus Arisaema in ruins of fortresses used in medieval Japan

Members of the genus Arisaema (Araceae) are perennial understory herbs that were traditionally used in medieval Japan in the treatment of flesh wounds resulting from warfare to prevent tetanus. This study aimed to elucidate the distribution of Arisaema in the ruins of fortresses dating from the medieval period in Japan. Two hypotheses were tested: that Arisaema are commonly found in the ruins of fortresses in central...

Author(s): Eiji Tanesaka

May 2017

Biological and antioxidant activity of Gunnera tinctoria (Nalca)

The endemic Chilean edible plant Gunnera tinctoria (Nalca) is highly appreciated in the south of Chile by the small farmers. Nevertheless, no background exists about his secondary metabolites. In the present study, in the leaf from G. tinctoria was investigated the content of bioactive compounds like coumaric acid, ascorbic acid and total phenols; the antioxidant capacity was evaluated by...

Author(s): Pedro Zamorano, Benjamín Rojano, Marcela Morales, Haroldo Magariños, Patricio Godoy and Ociel Muñoz

May 2017

Optimization of enzyme assisted extraction of polysaccharides from Poria cocos

Water-soluble polysaccharide was isolated from Poria cocus by enzyme-assisted method using orthogonal methodology. By single factor test and orthogonal group, the extraction conditions of water-soluble polysaccharide were investigated, such as liquid-solid ratio, temperature, time and pH. The optimum conditions for single factor were as follows Enzyme concentration (%), Extraction temperature oC, Extraction time/h,...

Author(s): Ashfaque A. Khaskheli, Shahzor G. Khaskheli, Ying Liu, Saghir A. Sheikh, Yan-Feng Wang, Aijaz H. Soomro, Xiaojiu Tian, Mamoun A. Homaida and Wen Huang

April 2017

Secondary metabolites from endophytic fungus from Lippia sidoides Cham.

Lippia sidoides Cham. (Verbenaceae) is a species native to the Brazilian northeast, widely used in popular medicine. Its leaves were used for the isolation of endophytic fungi and extraction of metabolites. Among them, three were selected according to fungitoxicity tests against the maize phytopathogenic fungus, Curvularia lunata (Wakker). However, the objective of this study was to identify the role of L. sidoides...

Author(s): Talita Pereira de Souza Ferreira, Gil Rodrigues dos Santos, Ilsamar Mendes Soares, Sergio Donizeti Ascêncio, Tarso da Costa Alvim, Chrystian de Assis Siqueira and Raimundo Wagner de Souza Aguiar

April 2017

Ethnobotanical study of ethnoveterinary plants in Kelem Wollega Zone, Oromia Region, Ethiopia

Questionnaire based cross sectional study design was conducted from November 2015 to April 2016 in Dale Sadi district area, Kellem Wollega Zone of Oromia regional state of Ethiopia, to identify potential medicinal plants used for treatment of the livestock ailments. In this study 50 species of medicinal plant species were identified which were categorized under 32 different families. Among the medicinal plants 45(90%)...

Author(s): Tolera Fufa Feyissa, Moa Melaku shigut, Tilahun Bekele Hailemariam, Tena Regassa and Nebiyu Kassa Kergano

April 2017

HPLC-UV fingerprint profile and bioactivity of Citrus aurantium var. deliciosa fruits: peel and seeds on certain plant-parasitic nematodes

A potential approach to valorize citrus peel (P) in addition to seed (S), which remain wastes of the juice abstraction manufacturing, is to custom them as accepted bionematicides. However, information on the limonoids as well aspolyphenolics contents of the peel and seeds of Citrus aurantium var. deliciosa were limited. In the present study, methanolic extracts of the peel and seeds of C. aurantium were analyzed using...

Author(s): Sabah Hussein El- Gayed, Abeer M. El Sayed,  and Ahlam M. Al-Ghonaimy, AbdelWahab Samia M.

April 2017

Specialization in ethnomedicinal plant knowledge among herbalists in the forest region of Rivercess County, Liberia

The ethnomedicinal uses of plants reported by 22 herbalists in the Rivercess County of Liberia show a rich knowledge of medicinal plant usage for both common and less common health problems. We set out with the objectives of documenting the ethnomedicinal plant knowledge and assessing gender differences in the use of the plants by male and female herbalists. Through semi-structured interviews conducted with herbalists,...

Author(s): Aiah Lebbie, François Kouamé and Edouard Kouassi

April 2017

Chemical composition, antiacetylcholinesterase inhibition and toxicity activities of essential oil from Hyptis dilatata (Lamiaceae) flowers

The content and chemical composition of the essential oil may vary in certain species according to the climatic period. The aim of this study was to evaluate the influence of seasonality on the chemical composition of the essential oil from Hyptis dilatata flowers, to perform biological activities such as antimicrobial, inhibition of acetylcholinesterase enzyme and to evaluate the toxicity of the essential oil using for...

Author(s): Sirley Pereira Almeida, Diana Maruja Sangama Mozombite, Antonio Alves de Melo Filho, Andreina G. de Andrade Laranjeira, Ana Cristina Gonçalves Reis de Melo, Regildo M. G. Martins, Jacqueline A. Takahashi, Vany P. Ferraz, Otoniel Ribeiro Duarte and Wanderli Pedro Tadei

April 2017

Antimicrobial activity of Annona crassiflora Mart. against Candida albicans

This study evaluated the antimicrobial activity of the ethanol extract of Annona crassiflora Mart., against the fungus, Candida albicans present in the oral microbiota. The tests showed that the fractions of ethanol extract of the root bark and wood root of A. crassiflora showed a positive result. Of the strains studied, three showed sensitivity to 12 fractions and sub-fractions of A. crassiflora (66%). In the strains...

Author(s): Amaro de Mendonça Cavalcante,  Karlos Antonio Lisboa  Ribeiro Junior, Eulália Camelo Pessoa de Azevedo Ximenes, Zenaldo Porfirio Silva, José Ivo Limeira dos Reis and Antonio Euzebio Goulart de Santana

April 2017

Insecticidal activity of Azadirachta indica A. Juss. extracts on Aleurocanthus woglumi Ashby (Hemiptera: Aleyrodidae)

The use of natural products with insecticidal action is a control method compatible with integrated pest management, since it reduces the impacts caused to human health and the environment. This study aimed to assess the effect of Azadirachta indica A. Juss. (Meliaceae) leaf and seed aqueous extracts, on citrus blackfly (Aleurocanthus woglumi Ashby). Citrus x latifolia Tanaka ex Q. Jiménez leaves infested with...

Author(s): Kleydejany Lima de Lemos, Raimunda Nonata Santos de Lemos, Fabíola Rodrigues Medeiros, Ester Azevedo da Silva, Mário Luiz Ribeiro Mesquita and José Ribamar Gusmão Araujo

March 2017

Ethnobotanical study of Arruda quilombo community in the State of Ceará, Brazil

The aim of the present study was to investigate the use and storage of medicinal plants in the Arruda quilombo community in the state of Ceará, Brazil. Semi-structured interviews were conducted for the determination of traditional knowledge. The qualitative-quantitative collective subject discourse method was used for the data analysis, focusing the discussion on six categories. The Chi-square test with a 5%...

Author(s): Gilmara Matias de Sousa, George Pimentel Fernandes, Marta Regina Kerntopf, Roseli Barbosa, Izabel Cristina Santiago Lemos, Dailon de Araújo Alves and Dayanne Rakelly de Oliveira

March 2017

Anti-inflammatory activity and modulate oxidative stress of Bucida buceras in lipopolysaccharide-stimulated RAW 264.7 macrophages and Carrageenan-induced acute paw edema in rats

Since oxidative stress is an important mediator that lead or maintain inflammatory processes, the aim of this work is to evaluate the effects of Bucida buceras on inflammatory response in lipopolysaccharide (LPS)-stimulated RAW 264.7 cells and anti-inflammatory effect and redox biomarkers in carrageenan-induced paw edema in rats. B. buceras also known as “black-olive“ belongs to the Combretaceae family and...

Author(s): Simon B. Iloki Assanga, Lidianys M. Lewis Luján, Armida A. Gil-Salido, Claudia L. Lara Espinoza, Daniela Fernandez Angulo, Jose L. Rubio-Pino and René Betancourt Riera

March 2017

Oxidative stabilization of palm olein with isoespintanol (2-isopropyl-3,6-dimethoxy-5-methylphenol) isolated from Oxandra cf xylopioides

Antioxidants are used to retard oxidative processes and improve the sensory and nutraceutical quality of cooking oils. Isoespintanol, a monophenol isolated from Oxandra cf. xylopioides, has shown a greater free radical scavenger ability than thymol (biosynthetic analog).  Isoespintanol antioxidant capacity was evaluated and compared to butylated hydroxytoluene (BHT). Cytotoxicity, thermal stability and effect on...

Author(s): Karol Zapata, Juan P. Arias, Farid B. Cortés, Camilo L. Alarcon, Diego L. Durango Restrepo and Benjamín A. Rojano

March 2017

Effects of Commiphora swynnertonii on weight and plasma cholesterol levels in Rattus rattus

Experimental studies that aimed to determine the effects of crude aqueous resin extracts of the Commiphora swynnertonii on plasma cholesterol levels and weight changes were carried out in rats (Rattus rattus). A total of 24 experimental rats divided into four groups with equal sample size (n=6) were used. Group one (G1) served as negative control that received 0.5ml of distilled water (0 mg/kg) orally. Groups 2 (G2), 3...

Author(s): Mdegela, R. H., Bakari, G. G., Simon, S. and Mosha, T. E. C.

March 2017

Pharmacological potential of Palicourea rigida kunth: A possible participation of flavonoid compounds

Palicourea rigida Kunth (Rubiaceae), also called “bate-caixa” or “douradão”, has been used as antihypertensive, antiulcerogenic, anti-inflammatory and analgesic by traditional communities. Pharmacological potential of the ethanol extract from P. rigida (EEPR) and two quercetin derivatives were investigated. Using the high performance liquid chromatography (HPLC) assay, EEPR was analyzed....

Author(s): Muiara Aparecida Moraes, Bruna Celeida Silva Santos, Rodrigo Luiz Fabri, Elita Scio, Maria Silvana Alves, Célia Hitomi Yamamoto, Mírian Pereira Rodarte, Glauciemar Del-Vechio-Vieira, Ana Lúcia dos Santos de Matos Araújo, Aílson da Luz André de Araújo and Orlando Vieira de Sousa

March 2017

In vitro cytotoxic potential of Yacon (Smallanthus sonchifolius) against HT-29, MCF-7 and HDFn cell lines

Yacon (Smallanthus sonchifolius) tubers and leaves have been used widely as foodstuff and as remedy for urinary ailments, muscle pain, hyperlipidemia and diabetes mellitus. Recent studies have investigated on isolating active components for their anti-cancer potential against melanoma, cervical cancer and colon cancer.  In this study, the cytotoxicity potential of hexane, methanol and DCM extracts of yacon leaves...

Author(s): Rachelle P. Mendoza, Warren S. Vidar and Glenn G. Oyong

March 2017

Ethnobotanical study of medicinal plants used by agro pastoralist Somali people for the management of human ailments in Jeldesa Cluster, Dire Dawa Administration, Eastern Ethiopia

Ethnobotanical study of medicinal plants in selected kebeles of Jeldesa cluster, Dire Dawa Administration, eastern Ethiopia was carried out with the aim of assessing and documenting the indigenous knowledge of medicinal plants used in the communities and preserves it to be used by the next generations. Ethnobotanical data collection was carried out from September 2015 to March 2016. Three study sites (kebeles) were...

Author(s): Shimels Ayalew, Atinafu Kebede, Akalu Mesfin and Getachew Mulualem

March 2017

Volatile constituents of Distichochlamys citrea M. F. Newman and Distichochlamys orlowii K. Larsen & M. F. Newman (Zingiberaceae) from Vietnam

The characterization of chemical constituents of hydrodistilled essential oils from the rhizomes of Distichochlamys citrea M.F. Newman and Distichochlamys orlowii Larsen & M.F. Newman collected from Pù Mát National Park, Nghệ An Province, Vietnam, was performed by means of gas chromatography-flame ionization detector (GC-FID) and gas chromatography-mass spectrometry (GC-MS) techniques. The main...

Author(s): Le Thi Huong, Dao T. M. Chau, Nguyen V. Hung, Do N. Dai and Isiaka A. Ogunwande

February 2017

Effects of lemon balm (Melissa officinalis) on behavioral deficits and memory impairment of rats surviving sepsis

Sepsis has become one of the most frequent causes of mortality in intensive care centres. So far, there is no effective pharmacotherapy that can prevent or improve the neurological consequences and enhance survival. The goal of this study is to investigate the neuroprotective effect of lemon balm (Melissa officinalis) on behavioural dysfunctions produced in sepsis-surviving rats. Adult male rats were subjected to caecal...

Author(s): João Eudes Filho, Dâmaris Silveira, Aluízio Carlos Soares, Fabiana Pirani Carneiro, Melissa Sousa de Assis, Franco Batista Leite, Niraldo Paulino, Greice Maria Souza, Mônica Valero da Silva, Stéphanie Marchiori, Karla Amaral, Nadyelle Targino de Melo, Vania Moraes Ferreira

February 2017

Medicinal plants and herbalist preferences around Bwindi Impenetrable National Park

Many people in Uganda, particularly in the rural areas depend on herbal medicine for health care. Although, medicinal plants are collected from different habitats, most of them are collected from the wild. Claims indicate that men use more forest products than women; and that women prefer younger vegetation succession stages as compared to those preferred by men for harvesting medicinal plants. However, there was no...

Author(s): Medius Kyoshabire, Esther Katuura, Anthony B. Cunningham and Robert Hoeft

February 2017

Anthelmintic activity of Artemisia annua in sheep-model

Artemisia annua L. is a well-known source of artemisinin, an antimalarial drug. This compound has been used in traditional medicine to treat malaria for many years. The anthelmintic property of A. annua has also been attributed to artemisinin, hence the belief that artemisinin could be useful as an alternative anthelmintic to control Haemonchus contortus in livestock. The present study focused on evaluating the...

Author(s): Ives Charlie da Silva, Pedro Melillo de Magalhães, Ilza Maria de Oliveira Sousa, Mary Ann Foglio, Eduardo Leonardecz, Sérgio Novita Esteves and Ana Carolina de Souza Chagas

February 2017

Mangiferin content, carotenoids, tannins and oxygen radical absorbance capacity (ORAC) values of six mango (Mangifera indica) cultivars from the Colombian Caribbean

Mango is one of the tropical fruits of greater production and consumption in the world, and a rich source of bioactive compounds, with various functional properties such as antioxidant activity. In Colombia, mango’s market is very broad and diverse. However, there are very few studies that determined the content of bioactive secondary metabolites. The objective of this study was to evaluated the content of...

Author(s): Marcela Morales, Santiago Zapata, Tania R. Jaimes, Stephania Rosales, Andrés F. Alzate, Maria Elena Maldonado, Pedro Zamorano and Benjamín A. Rojano

February 2017

Effect of the extract of Hypericum perforatum on neurodevelopment of regions related to pain control and convulsion

Hypericum perforatum (HP) is well-known by the population of the world as herb with antidepressant effect. Its various components, such as hypericin and hyperforin, provide many other effects for this plant, for example, antinociceptive and anticonvulsant. The aim of this work was to determine whether HP administration during pregnancy can cause changes in neurodevelopment related to pain control and seizures in rats...

Author(s): Leandro Véspoli Campos, Martha de Oliveira Guerra, Vera Maria Peters and Rita de Cássia da Silveira e Sá

February 2017

Response of Rheum australe L. (rhubarb), (Polygonaceae) an endangered medicinal plant species of Kashmir Himalaya, to organic-inorganic fertilization and its impact on the active component Rhein

Many medicinal plant species, including Rheum australe L. (rhubarb), are being exploited from the wild source at an alarming rate. This has resulted in the loss of biodiversity of the species. Roots of R. australe have been used in traditional medicine for years for treating various kinds of diseases. The species has been ruthlessly harvested from the wild source and has become endangered. Consequently, preventing the...

Author(s): H. Bano, M. A. A. Siddique, R. C. Gupta, M. Ashraf Bhat and S. A. Mir

February 2017

Protective effect of eucalyptus oil on pulmonary destruction and inflammation in chronic obstructive pulmonary disease (COPD) in rats

Eucalyptus oil (EO), an essential oil isolated from Eucalyptus leaves, was examined for its effect on lipopolysaccharide (LPS) and Klebsiella pneumoniae-induced COPD in rats. The COPD model was induced by instilling intratracheally with LPS and K. pneumoniae. The test compound, EO (30, 100 and 300 mg/kg), prednisone acetate (10 mg/kg) or vehicle was instilled intragastrically after three weeks exposure to LPS and K....

Author(s): Lin Wang, Jianbo Sun, Wanzhong Li, Yanna Lv, Weiwei Shi, Gang Wang and Chunzhen Zhao

February 2017

Laxative properties of aqueous and methanolic extracts of mature stem bark of Neoboutonia velutina Prain (Euphorbiaceae) in rats

Neoboutonia velutina. Prain is a plant used in Cameroonian ethnomedicine for the treatment of digestive disorders such as constipation. This study was conducted to evaluate the laxative properties of aqueous and methanolic extracts of N. velutina in rats. The laxative properties as mentioned by the consulted traditional healer were firstly determined, through an evaluation of fecal emission outset, number of wet...

Author(s): Gilbert Ateufack, Francine Kengne Nono, William Nana Yousseu, Herve Tchoumbou Tadjoua, Rostand Breuil Feudjio Dongmo and Albert Kamanyi

February 2017

Bioactive rich extracts from Terminalia ferdinandiana by enzyme-assisted extraction: A simple food safe extraction method

A food grade compatible enzyme assisted extraction (EAE) technique for extracting bioactive compounds from freeze-dried Kakadu plum puree was evaluated. To optimise the extraction, a central composite rotatable design (CCRD) was conducted and effects of solvent concentration, enzyme concentration and time of reaction on extracted levels of free ellagic acid (fEA), ascorbic acid (AA) and total phenolic content (TPC) were...

Author(s): Mridusmita Chaliha, David Williams, David Edwards, Sharon Pun, Heather Smyth and Yasmina Sultanbawa

January 2017

In vitro studies of larvicidal effects of some plant extracts against Anopheles gambiae larvae (Diptera: Culicidae)

Larvicidal effects of plant extracts against larvae of Anopheles gambiae were studied in the malaria entomology laboratory at Mendefera. The aim of the study was to evaluate ethanol and hot water extracts from leaves of seven different plants, viz., Azadirachta indica, Eucalyptus globulus, Tagetes minuta, Datura stramonium, Lantana camara, Ricinus communis and Jatropha curcas, as natural larvicides against third instar...

Author(s): Ghebriel Okbatinsae and Adugna Haile

January 2017

New insights of Nettle (Urtica urens): Antioxidant and antimicrobial activities

Urtica urens is classified into the sub family of Rosales, belonging to the Urticaceae family. Their well-established beneficial properties to human health were mainly related to their phenolic content. Nettle extracts showed that an antioxidant and antimicrobial potentials. Among the different nettle extracts methanol extract (EMO) has the highest phenolic content (86.5±1.36 mg EGA/g DM) and lowest value was...

Author(s): Lobna Maaroufi, M. Sazzad Hossain, Wiem Tahri and Ahmed Landoulsi

January 2017

The genus Eupatorium L. (Asteraceae): A review of their antimicrobial activity

In recent years, the number of infectious diseases linked to the occurrence of bacterial and fungal resistance has increased, leading to extensive search for new drugs to treat these infections. Species of the Asteraceae family and the genus Eupatorium, have high biological potential and are used in folk medicine to treat various diseases. This review article presents the main phytochemical and biological...

Author(s): Antonio Carlos Nogueira Sobrinho, Selene Maia de Morais, Elnatan Bezerra de Souza and Raquel Oliveira dos Santos Fontenelle

January 2017

Hypoglycaemic effect of fractions and crude methanolic leaf extract of Phyllanthus fraternus in streptozotocin - induced diabetic and normal rats

Treatments of diabetes with available agents come with one or more side effects, hence, the need for continual search of alternative treatment agents from medicinal plants. This study was designed to analyse qualitatively and quantitatively some phytochemicals in methanolic extract in Phyllanthus fraternus and evaluate their hypoglycaemic activity in both diabetic and normal rats. Sixty-six rats were used of which...

Author(s): Nadro, M. S. and Elkanah, G.

January 2017

Chemical composition, antioxidant and topical anti-inflammatory activities of Croton cordiifolius Baill. (Euphorbiaceae)

Croton cordiifolius is widely used in Brazilian Caatinga folk medicine to treat general inflammation, pain, and gastrointestinal disturbances. Currently, its medicinal properties are not well understood, owing to the absence of chemical and pharmacological studies. The aims of this work were to analyze the chemical composition of C. cordiifolius stem bark and evaluate its in vitro antioxidant and in vivo...

Author(s): Iasmine Andreza Basilio dos Santos Alves, Simone Maria dos Santos, Raudiney Frankilin Vasconcelos Mendes, José Welinton da Silva, Maria de Fátima Rodrigues, Bárbara de Azevedo Ramos, Márcia Vanusa da Silva, Maria Tereza dos Santos Correia, Fernanda das Chagas Angelo Mendes Tenório, Roberta Jeane Bezerra Jorge, René Duarte Martins, Julianna Ferreira Cavalcanti de Albuquerque and Rafael Matos Ximenes, Karina Perrelli Randau

January 2017

Induction of biochemical active constituents of Jojoba (Simmondsia chinensis (Link) Schneider) callus affected by hormones

The present study aimed to identify some metabolites products obtained from different jojoba callus tissue extracts using gas chromatography/mass spectrometry analysis (GC-MS). It is known that Jojoba, a medicinal and oil-yielding, has multi-purpose uses. In addition, it produces toxins, fatty acids, phenolic compounds and other secondary metabolites from callus identified using GC-MS. Despite the direct effect of 2,4-D...

Author(s): Mohei El-Din Solliman, Wael F. Shehata, Heba Allah A. Mohasseb, Mohammed I. Aldaej, Abdullatif A. Al-Khateeb, Solliman A. Al-Khateeb, Adel E. A. Hegazy  and  Hesham M. Abdel-Moneim

January 2017

Comparative physicochemical, phytochemical and acute toxicity studies of two Ocimum species in Western Uganda

Ocimum gratissimum and Ocimum suave are species belonging to the Lamiaceae family; they have been domesticated and are widely grown in gardens in Western Uganda for its claimed beneficial effect in ethnomedical practice. This study was aimed at comparative evaluation of the physicochemical, phytochemical and acute toxicity potentials of their leaves. Dried leaves of O. gratissimum and O. suave were subjected to...

Author(s): Abayomi M. Ajayi, Annet Naluwuge, Peter Buyinza and Ivan Luswata

January 2017

Chemical profiling and chemical standardization of Vitex negundo using 13C NMR

Chemical profiling and standardization of the defatted methanol extract of the leaves of Vitex negundo L. were carried out using 13C nuclear magnetic resonance (NMR) analysis followed by chemometric analysis of the chemical shift data. Chemical profile was obtained using a k-means cluster profile and chemical standardization which was achieved using a multivariate control chart. The V. negundo samples were made up of...

Author(s): Lolita G. Lagurin, John Daniel J. Magsalin, Anthony R. Zosa and Fabian M. Dayrit

December 2016

Chemical composition and antifungal activity of essential oil and fractions extracted from the leaves of Laurus nobilis L. cultivated in Southern Brazil

Laurus nobilis L., popularly known as laurel, is a tree belonging to the Lauraceae family, native to Asia. It has long been used in traditional medicine to treat rheumatic disorders, and as a gastric stimulant. The aim of this study was to characterize the chemical composition of essential oils (EO) and fractions from laurel by column chromatography, and to evaluate their antifungal activity. The EO of L. nobilis leaves...

Author(s): Carla M. M. Fernandez-Andrade, Maurício F. da Rosa,  Édela Boufleuer, Fabiana Borges Padilha Ferreira, Camila Cristina Iwanaga, José E. Gonçalves, Diógenes A. G. Cortez, Cleide Viviane Buzanello Martins, Giani Andrea Linde, Márcia R. Simões, Viviane S. Lobo and Zilda C. Gazim

December 2016

Flavonoids as photoprotective agents: A systematic review

There is a growing need for research of photoprotective molecules from natural sources. Flavonoids have shown significant absorption in ultraviolet A (UVA), ultraviolet B (UVB) region, due to their chemical structure with conjugated double bonds, and may be used as ingredients in cosmetics formulations for skin protection. This systematic review reports what has been researched over the past decade on flavonoid and...

Author(s): José Marcos Teixeira de Alencar Filho, Pedrita Alves Sampaio, Emanuella Chiara Valença Pereira, Raimundo Gonçalves de Oliveira Júnior, Fabrício Souza Silva, Jackson Roberto Guedes da Silva Almeida, Larissa Araújo Rolim, Xirley Pereira Nunes, and Edigênia Cavalcante da Cruz Araújo,

December 2016

Polyphenols derived from four indigenous Indian fruits for cancer chemoprevention and chemotherapy

Cancer is one of the major causes of death worldwide, including developing and underdeveloped nations. Mortality and morbidity data suggest that incidences are higher than those of the cardiovascular diseases. High cost and occurrence of numerous side and adverse effects associated with conventional anticancer regimes has necessitated shifting the focus towards the practice of traditional alternative and complementary...

Author(s): Sutapa Biswas Majee, Vansh Khattry, Vaibhav Agarwal and Gopa Roy Biswas

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