Journal of
Medicinal Plants Research

  • Abbreviation: J. Med. Plants Res.
  • Language: English
  • ISSN: 1996-0875
  • DOI: 10.5897/JMPR
  • Start Year: 2007
  • Published Articles: 3804

JMPR Articles

In vivo hypotensive activity on the albino’s rat and in vitro antioxidant activities of aqueous extract from Guibourtia tessmannii (Harms) J. Leonard (Cesalpiniaceae) stem barks

March 2023

In Central Africa, stem bark from Guibourtia tessmannii is used in traditional pharmacopeia for the treatment of hypertension. The aim of this study was to scientifically verify the traditional use in the treatment of metabolic pathologies such as arterial hypertension and evaluated its pharmacological potential. Phytochemical tests were evaluated by standard method of laboratory. Antioxidant activities were determined...

Author(s): Noreen Orianna Koumba Madingou, Patrice Soulounganga, Jean Alban Ondh-Obame, Gontran Nsi, Alain Souza, Aristide Traoré and Alfred Sababenedyo Traoré  

Effects of millet on calcium oxalate crystal growth and dissolution

March 2023

The influence of aqueous extract of millet on the crystallization and the dissolution of calcium oxalate (CaOx) crystals were investigated in detail under supersaturated and artificial urinary circumstances in order to understand the effect of the water-soluble components of millet on CaOx kidney stones in humans. To investigate the inhibition effect, different volumes of millet extract were added separately to the...

Author(s): Samantha A. Ranaweera, Vindya U. Liyanagamage and Mark G. White  

Traditional knowledge of plants used against upper respiratory tract affections in the Littoral Region of Cameroon

February 2023

Traditional medicine is used by people as an alternative to orthodox drugs to treat respiratory infections. The aim of this research was to document traditional recipes used in the treatment of upper respiratory tract infections such as pharyngitis, cold, and sinusitis in peri-urban and rural areas of the Littoral Region of Cameroon. Ethnobotanical surveys were carried out using semi-structured interview model in French...

Author(s): Ngotta Biyon Jacques Bruno, Doumbe Makembe Lea Clémence, Nnanga Jeanne Flore, Mvogo Ottou Patrice Brice, Nguimfack Dongmo Jasmine and Ndongo Din  

Evaluation of antibiotic efficacy of Ocimum gratissimum L. essential oil against Staphylococcus aureus and Pseudomonas aeruginosa

February 2023

Ocimum gratissimum essential oil (EOGT) has been evaluated for its antibacterial efficacy, and its combinational therapy with antibiotics may enhance the therapeutic efficiency against infection-causing bacteria. Herein, we evaluated the chemical composition of EOGT and its antibiotic efficacy against Staphylococcus aureus and Pseudomonas aeruginosa. GC-MS and GC-FID analyzed EOGT. The antibiotic efficacy was determined...

Author(s): Leonardo de Paiva Belo, Flávia Costa de Moraes, Celia Hitomi Yamamoto and Orlando Vieira de Sousa

In-vitro assessment of antibacterial effects of combined crude extracts of S. glaucescens and C. swynnertonii with antibiotics

February 2023

Currently, there is an upsurge of bacterial resistance in single-drug treatment regimens. This has stimulated a growing interest in research and development of new antibacterial agents containing several ingredients as one of the means to combat bacterial resistance. Herb-antibiotic combination therapy is one of the reported effective treatment regimens to combat antimicrobial resistance. This study was aimed to assess...

Author(s): Mary George Ochollah, Faith Philemon Mabiki, Lughano Jeremy Moses Kusiluka, Robinson Hammerthon Mdegela and John Elmerdahl Olsen  

Pachyrhizus toxicity: Genetic variability of mature and immature seeds and its effects on Sclerotium rolfsii and Ralstonia solanacearum

January 2023

Pachyrhizus seeds-induced toxicity is very well-known to have developed in humans, fishes, insects, and some micro-organisms. Yet, there is a paucity of studies addressing it in their germplasm, as well as its effects on some phytopathogens. This work aimed to assess the Pachyrhizus genetic variability on toxicity and to determine Pachyrhizus extract toxicity on Sclerotium rolfsii and Ralstonia solanacearum in vitro. In...

Author(s): Thiago MP e Silva, Rândrea GV Guimarães, Anne KB Martins, Danilo F Silva Filho and César A. Ticona-Benavente  

Medicinal plants for the treatment of malaria and typhoid diseases

January 2023

The review concentrated on current literature on medicinal plants for the treatment of malaria and typhoid related diseases, highlighting information about their ethnobotany. The entire plants reviewed showed strong activities, establishing their different traditional applications and capability to control or eliminate malaria and typhoid diseases. Malaria and typhoid diseases are the most problematic public health...

Author(s): Olusola, L. F., Baba, J. and Muhammad, I. L  

Bioprospecting of the antifungal activity of Patchouli essential oil (Pogostemon cablin Benth) against strains of the genus Candida

January 2023

The incidence of infections caused by Candida has increased worldwide and these strains are becoming resistant to their respective drugs, requiring the search for new drugs with greater efficacy and safety. Natural products are an alternative means of treatment. The essential oil (EO) stands out among these products, due to some biological activities relevant to human health, including antibiotic and antifungal...

Author(s): Da Cunha S. M. D., Alves C. A., Ribeiro L. S. M., Macedo M. A., Da Silva A. L. S., Cunha F. N., De Lima B. V. S. L., Silva D. F., Lima E. O. and De Oliveira Filho  

Valuation study on the extracts of Ilex guayusa Loes. as an antioxidant and anti-aging raw material

January 2023

Ilex guayusa Loes. is a medicinal plant used by people of the Ecuadorian Amazon for treating various diseases and for its stimulating properties. In recent years, several studies have shown this plant to possess a high concentration of phenolic compounds and a high antioxidant potential, allowing it to be used as an ingredient for cosmetic formulations. This research confirms the presence of phenolic compounds between...

Author(s): Paco Noriega, Christian Larenas, Alba Nadal, Ricardo Fonseca, Mishell Silva, Lissette Calderón and Tatiana Mosquera,  

Determination of total phenolic and flavonoid content, antioxidant and cytotoxic activity of the methanol extract of Acacia nilotica pods

December 2022

Acacia nilotica is a medicinal plant used in Niger republic for the treatment of gastrointestinal diseases. The aim of this study was to investigate total phenolic and flavonoid content, antioxidant and cytotoxic activity of the A. nilotica pods collected from Niger republic. The phytochemical contents were examined by colorimetric methods. Antioxidant activity of the methanol extract was screened using DPPH, ABTS and...

Author(s): Maman Manzo Lawaly, Khalid Ikhiri and Liu Yu  

Antiedematogenic activity of Petiveria alliacea L. in bothropic poisoning

December 2022

The biodiversity of the Brazilian biomes inspires interest in research about the biological activities of the molecules present in the flora. In this line, Petiveria alliacea a common plant species in the savanna of Tocantins, reported in the treatment for snakebites, was studied to analyze the phytochemical profile and evaluate the activity on the edema caused by Bothrops moojeni snake venom. A qualitative...

Author(s): Marcio Trevisan, Patricia Siqueira de Melo Rodrigues, Antônio Ítalo dos Santos Nunes, Milena Dos Santos Falcão, Hemilly Cirqueira Martins, Elisandra Scapin, Marcio Galdino Dos Santos and Carla Simone Seibert  

Phytochemical study and anti-radical activity of extracts from the oil seeds of Desbordesia glaucescens (Engl.)Tiegh. from Gabon

November 2022

The report focused on the extraction of oilseeds of Desbordesia glaucescens (Engl.) Tiegh. from Gabon as well as on the phytochemical study and evaluation of the anti-free radical activity of the extracts obtained. The extraction was carried out by cold maceration with solvents of increasing polarities: hexane, tricholroethylene, acetone, ethanol and distilled water. The anti-free radical activity was measured by...

Author(s): Medza M’Ella Darina Livia, N’Negue ép Mezui-Mbeng Marie Andrée, Edou Engonga Prosper, Mengome Line Edwige, Engone Obiang Nestor, Aboughe-Angone Sophie

Ethnobotanical study, phytochemical composition and in vitro antioxidant activity of the methanol extracts of thirty-two medicinal plants from Southern Nigeria

October 2022

The prevalent disease conditions globally, the detrimental effects, and the resistance of microorganisms to synthetic drugs are really worrisome. Measures to checkmate these situations include researches on the role of medicinal plants in health care delivery. This study is aimed at assessing the antioxidant activities of some medicinal plants normally used for the treatment of various ailments in southern Nigeria and...

Author(s): Ibanga O. Isaac,, Usoro M. Etesin, Elijah J. Nya, Emmanuel J. Ukpong, Ufikairom G. Isotuk and Udo J. Ibok  

Ethnobotanical survey and phytochemical screening of aqueous extracts from Detarium microcarpum Guill. & Perr in Mali

October 2022

Detarium microcarpum Guill. & Perr is a tree which belongs to Caesalpiniacea family and can reach up 10 m of height, with a horizontal root system. It is confined to the arid regions of West and Central Africa, where it mainly occurs in savannah. The aim of this work is to collate information on the use of Detarium microcarpum in folk medicine by traditional health practitioners and herbalists. Moreover, a...

Author(s): N. Dembele, A. A. Somboro, M. Badiaga, S. Cisse, M. Cisse, I. Togola, P. Nick and N. Traore

Aqueous extracts of Lentinula edodes, Pleurotus pulmonarius, and Pleurotus sajor-caju: Antifungal activity and inhibition of exoenzyme production by Candida albicans

October 2022

This study was aimed at evaluating the effects of aqueous extracts of Lentinula edodes (SHI), Pleurotus pulmonarius (PUL), and Pleurotus sajor-caju (PSC) on the growth of eight yeast species and the exo-enzyme production by Candida species after exposure to the extracts, which were prepared with the cold extraction methodology and tested against yeasts by the broth microdilution method. Proteinase and phospholipase were...

Author(s): Morgana Lüdtke Azevedo, Carolina Lambretch Gonçalves, Alessandro Menna Alves, Caroline Neugebauer Wille, Adriana Etges, Patrícia da Silva Nascente, and Rafael Guerra Lund,  

Ethnopharmacological investigation on Msindzano, a beauty mask used by Comorian women: What plants for what mixtures, for what applications?

September 2022

Although extensively used by Comorian women, limited information exists on Msindzano beauty masks. Thus an ethnopharmacological survey was conducted on two islands of the Comoros archipelago: Ndzuani and Ngazidja. An open-ended, semi-structured questionnaire was employed for data collection on the different plants used for Msindzano preparation, their different mixtures and their different applications. A total of 348...

Author(s): Said Hassane Soidrou, Radjab Youssouf, Azali Ahamada Himidi, Ahmed Msahazi and Abdellah Farah  

Piper rivinoides Kunth: A medicinal plant that preserves bioactive chemical substances in its essential oil throughout the seasons

August 2022

The chemical composition and seasonal variation of essential oils (EO) extracted from the aerial parts of the traditional medicinal plant Piper rivinoides were analyzed using gas chromatography (GC) coupled with mass spectrometry (MS) and GC coupled with flame ionization detector (GC-FID) technique, respectively. The wild plants were collected from two different sites in the Atlantic Forest. The analysis allowed us to...

Author(s): Jéssica Sales Felisberto, Ygor Jessé Ramos,, George Azevedo de Queiroz,  Elsie Franklin Guimarães, André Mesquita Marques and Davyson de Lima Moreira,  

Ethno botanical study of medicinal plants used by Baka people in the treatment of erectile dysfunction

August 2022

Erectile dysfunction is a disease that is increasingly affecting men. The study examined the traditional use of medicinal plants in the treatment of erectile dysfunction among the Baka people in the eastern region of Cameroon. The study took place over interspersed periods from January 2018 to January 2021 in 9 villages. Forty-four people were interviewed via a questionnaire. One hundred and fifty-nine citations and 71...

Author(s): Natacha NANA AFIONG, Jean Lagarde BETTI, Pascal BILLONG FILS, Armand NDEDY BILE, Farick Oumar NJIMBAM, Stéphanie TIENTCHEU WOMENI, Patrice MVOGO OTTOU and Evariste FONGNZOSSIE FEDOUNG  

Medicinal plants and onychomycosis: potential and evidence of antifungal activity - an integrative review of the literature

July 2022

Onychomycosis is a fungal infection of the nails, also known as nail mycosis and Tinea unguium, which affects 6.9 to 23.2% of the general population. It is most commonly found in people aged 60 years and older. Onychomycosis is caused by dermatophyte fungi, non-dermatophyte filamentous fungi and yeast. Treatment includes topical or oral antifungal drugs. The use of other auxiliary, alternative and/or complementary...

Author(s): Bruna Lima Perissato and Reginaldo dos Santos Pedroso  

Tracking antibacterial components of Pteris multifida Poir and its antibacterial mechanism

June 2022

Pteris multifida is an effective Chinese herb for treating dysentery caused by Escherichia coli. It might be a good veterinary antibiotic alternative. In this study, we optimized the extraction condition based on the antibacterial activity of crude extracts from P. multifida, tracked its antibacterial components, and investigated their antibacterial activity, as well as its antibacterial mechanism. The results revealed...

Author(s): Zhong Wang#, LiQi Wang#, JingJing Qian, PingYao Nan and XiaoYing Wang  

Phytochemical composition and in vitro antileishmanial activity of Bidens pilosa, Tithonia diversifolia and Sonchus oleraceus extracts

June 2022

Leishmaniasis is the second-largest parasitic killer in the world (after malaria). Currently, there are no effective vaccines or therapeutic interventions thus creating a gap for new alternative remedies in the management of the disease. Medicinal plants offer this attractive option as antileishmanial agents since they are relatively safe, locally available and affordable. The study assessed antileishmanial activity of...

Author(s): Thomas O. Momanyi, Josphat C. Matasyoh, Stephen M. Karori and Johnstone M. Ingonga  

In vivo antimalarial activity, safety and phytochemical screening of Canthium multiflorum (Schumach. &Thonn.) Hiern (Rubiaceae)

June 2022

Canthium multiflorum (Thonn.) Hiern (Rubiaceae) is a popular herb used by traditional healers in western Burkina Faso. C. multiflorum leaves are widely used in decoction to treat malaria. The present study aims to evaluate its in vivo potential against malaria parasites in mice. The antimalarial activity of the organic and aqueous extracts of C. multiflorum leaves was evaluated on Plasmodium berghei Anka in NMRI mice...

Author(s): KOAMA Benjamin Kouliga, YERBANGA Rakiswendé Serge, DA Ollo, YOUGBARE Sibidou, NATAMA Hamtandi Magloire, OUEDRAOGO Georges Anicet, OUEDRAOGO Jean Bosco, and TRAORE/COULIBALY Maminata  

Medicinal plants of the African traditional pharmacopoeia in the management of bovine trypanosomosis: A review

June 2022

Traditional medicine has remained the most affordable and readily available source of treatment for primary care in poor African communities. Despite the increasingly common practices of traditional medicine to treat animal diseases, this rich endogenous knowledge is not sufficiently documented. The objective of this review is to synthesize information on ethnoveterinary practices to treat bovine trypanosomiasis in...

Author(s): C. Iwaka,, E. V. B. Azando, F. C. C. Hountondji, H. S.S. Worogo, E. Y. Attakpa, P. A. Olounlade, and M. S. Hounzangbe-Adote

Medicinal plants in oral health and the intergenerational transfer of knowledge: Resilience to cocoa culture in southern Bahia

May 2022

Ethnobotanical surveys have proved plant usage in the treatment of oral diseases; however, in areas where cocoa farming influenced socioeconomic reality there is a lack of information about preservation of traditional knowledge related to oral conditions treatment. Family Health Strategy (FHS) users and community experts were interviewed with socioeconomic characteristics and ethnobotanical information being obtained...

Author(s): Bolívar de Oliveira Landi, Carlos Eduardo Dias Igídio, Brenda di Pace Lucena, Marcelo Inácio Ferreira Ferraz, Gabriel Bastos Teixeira and Aline Oliveira da Conceição  

Anti-quorum sensing potential of Ageratum conyzoides L. (Asteraceae) extracts from Burkina Faso

May 2022

Pseudomonas aeruginosa causes infections in humans, particularly immune-compromised patients with cystic fibrosis, severe burns, and HIV, resulting in high morbidity and mortality. The pathogenic bacteria, P. aeruginosa, produces virulence factors regulated by the mechanism called quorum sensing system. The aim of this study was to assess the anti-quorum sensing activity of Ageratum conyzoides extracts. Chloroform...

Author(s): Eli Compaoré, Vincent Ouédraogo, Moussa Compaoré, Ablassé Rouamba, and Martin Kiendrebeogo

Ethnobotanical and ethno-pharmacological approach to ichthyotoxic plants of Gabon

May 2022

This ethnobotanical and ethno-pharmacological study was conducted to know the plants used in fishing practices and to show their importance in traditional medicine in Gabon. For this study, 100 questionnaires were administered to individuals in the fishing and traditional medical domains. 701 plants belonging to 16 different floristic families, including Fabaceae (41%), Rubiaceae (13%), and Rutaceae (15%) were commonly...

Author(s): Ulrich Gauthier Mayombo Mouele, Christiane Atteke Nkoulembene, Bertrand Kokolo, Silas Lendzele Sevidzem and Ibrahim  

Herbal medicine development and compliance to regulatory guidelines in Imo State Nigeria

April 2022

Herbal medicine is an important age-long resource for healthcare. The aim of this study was to determine the development of herbal medicine in relation to compliance to regulatory guidelines and product development in pursuance of the integration of herbal medicine into the healthcare system in Nigeria. Using Imo State as a case study, a cross-sectional investigation was conducted among the Traditional Medicine...

Author(s): Adigwe P. Obi, Builders F. Philip, Ibekwe, N. Nneka and Onavbavba Godspower  

Antioxidant and antihyperlipidemic activities of unique nicotinyl polysaccharide from the green seaweed Ulva pertusa

April 2022

Nicotinyl derivative of polysaccharide (NU) from the green seaweed Ulva pertusa (Chlorophyta) has unique structure and strong antioxidant activity in vitro. In the present study, in vivo antioxidant and antihyperlipidemic activities were tested in the livers of hyperlipidemic mice. Activity levels of superoxide dismutase, glutathione peroxidase (GSH-PX), catalase, and malondialdehyde were observed. At the 500 mg/kg...

Author(s): Yuzhou Wan, Xintao Chang, Lin Liu, Shaopeng Wang, Huimin Qi and Fang Yan  

In vitro antiproliferative potential of crude extracts from Carica papaya L. (Caricaceae) black seeds against prostate cancer cell lines'

April 2022

Black seeds from papaya plants are utilized as traditional medicine in African and Asian cultures to improve the functioning of the male reproductive system and management of prostate cancer. This study analyzed the phytochemical composition, antiproliferative activity and cytotoxicity of Carica papaya black seeds against the prostate cancer cells and Vero cells. Phytochemical screening was performed by standard...

Author(s): Benson Mcheza Kateihwa, Hulda Swai, Jeremiah Waweru Gathirwa and Elingarami Sauli  

Phytochemical analysis and safety evaluation of ethanol roots extract of Erythrina sacleuxii hua in Wistar albino rats

April 2022

Erythrina sacleuxii, one of five Erythrina species found in Kenya, is a stiffly multi-branched deciduous tree reported to have antiplasmodial, antifungal, anti-bacterial and anti-cancer activities. This study aimed at evaluating acute and sub-acute oral toxicity of E. sacleuxii roots ethanolic extract. Phytochemical analysis was conducted on Fourier transform infrared spectroscopy and Gas Chromatography-Mass...

Author(s): Mwanasiti O. Mwakumanya, Florence A. Ng’ong’a, Mutinda C. Kyama and Esther N. Maina  

Analgesic, anti-inflammatory and oxytocic activities of Dracaena steudneri Engl. stem bark aqueous extract in Wistar rats

April 2022

Dracaena steudneri Engl. (Dracaenaceae) is a medicinal plant that is used in labour by traditional birth attendants to induce labour, relieve pain and treat various diseases; albeit no documentation. This study determined the analgesic, anti-inflammatory and oxytocic effects of the D. steudneri stem bark aqueous extract. D. steudneri stem bark was collected, authenticated, oven-dried at 45ºC for 48 h, pulverized...

Author(s): Mercy Gladys Tenywa, Amon Ganafa Agaba, Clement Olusoji Ajayi, Casim Umba Tolo and Esther Katuura  

Antibiotic potential of a crude ethanol extract from Asplenium serratum L. fern leaves

March 2022

Asplenium serratum L. (Aspleniaceae) is a terrestrial, epiphytic or humicole fern used as traditional medicine in different countries to treat infection. As such, this study aimed to assess the antibacterial potential of a crude ethanol extract from A. serratum leaves against multidrug-resistant bacteria from a hospital setting. Fern leaves were dried and ground using 96° Gay Lussac ethanol, with the extract...

Author(s): Marcelo Guerra Santos, Sâmella Schuindt Leal, Fábio Aguiar-Alves and Leandro Rocha  

Acute toxicity, analgesic, and smooth muscle relaxant effects of the aqueous root extract of Asparagus racemosus from Kenya

March 2022

The plant Asparagus racemosus is used traditionally in Kenya for a variety of medicinal purposes including in the management of pain, asthma, and premature labour. However, a dearth of empirical studies means that there is limited information on the acute toxicity and pharmacological effects to support these uses by the local variety of the plant. The aim of this study was, therefore, to evaluate the acute toxicity,...

Author(s): Godfrey Mayoka, Peggoty Mutai, Faith Okalebo and Daniel Juma  

Brown macroalgae: Promising sources of bioactive products against human herpesviruses

March 2022

Marine brown macroalgae have stood out as important sources of new bioactive products, such as antimicrobial, anticoagulant, anti-inflammatory and antiviral drugs. This study aimed to review the literature on the applications of products derived from brown macroalgae as antiviral agents against human herpesviruses. To date, species of seven distinct orders of brown algae have been studied for this purpose, such as...

Author(s): Maria Leonisa Sanchez Nuñez, Vitor Won-Held Rabelo, Izabel Christina Nunes de Palmer Paixão and Valéria Laneuville Teixeira,  

Flavonoid content and antioxidant potential of leaf extracts of Passiflora setacea cv BRS Pérola do Cerrado, a new wild passion fruit cultivar

February 2022

Passiflora setacea D.C. is a wild species native to the Brazilian Cerrado, with agronomic and medicinal potentials. The cultivar BRS Pérola do Cerrado is the first registered and protected cultivar of a wild Passiflora and has become an alternative to the passion fruit market due to its desirable characteristics for food, ornamental and pharmaceutic industries. Since plant tissue culture techniques are considered...

Author(s): Raphaela Santos-Tierno, Renata Garcia, Eduardo Fonseca, Fábio Faleiro, Davyson Moreira, Georgia Pacheco and Elisabeth Mansur  

Antioxidant and DNA damage protective activities of selected endophytic actinobacteria isolated from Harpagophytum procumbens: A Kalahari desert-adapted plant

February 2022

Given that synthetic antioxidants are currently in use and have been demonstrated to have known negative side effects, it is important to look for natural antioxidant sources. Endophytic actinobacteria, especially those associated with medicinal plants, are one understudied source. The goal of this study was to investigate whether the secondary metabolites of endophytic actinobacteria isolated from Harpagophytum...

Author(s): Magdalena Elizabeth Lang, Timothy Sibanda, Stefan Louw and Jean Damascène Uzabakiriho  

Antibacterial, antiquorum sensing, antibiofilm activities and chemical profiling of selected South African medicinal plants against multi-drug resistant bacteria

February 2022

South African indigenous plants have been predominantly studied for their antibacterial abilities, overlooking their antipathogenic and antivirulence (also known as antiquorum sensing) potential. Hence, this study explored the selected medicinal plants as possible agents capable of interfering with bacterial growth, quorum sensing and biofilm formation and identified their respective bioactive compounds. Ten medicinal...

Author(s): Itumeleng Tsebang Baloyi, Idowu Jesulayomi Adeosun, Abdullahi Ahmed Yusuf and Sekelwa Cosa  

Antiplasmodial activity and phenolic composition of Brazilian Salix humboldtiana Willd. extract and fractions

February 2022

Salix humboldtiana Willd. (Salicaceae) colonizes Brazilian riverine forests and, besides other congeneric species, is traditionally used to treat fever. In folk medicine, it is even used as a Quinine substitute to treat malaria fever. Although its occurrence worldwide was largely reduced between 2000-2015, in Brazil, the case numbers induced by Plasmodium falciparum have increased. Thus, new tools and strategies are...

Author(s): Ianna Dias Ribeiro Silva, Uêbem Fernandes Ramos, Luciana Esquerdo Cerqueira, Andressa Santa Brígida da Silva, Geraldo Alves Damasceno Junior, Carlos Alexandre Carollo, Ivanildes dos Santos Bastos, Patrícia Puccinelli Orlandi, Heike Markus-Michalczyk and Wagner Luiz Ramos Barbosa  

Evaluation of the anxiolytic effects of acute administration of Passiflora alata extract in wistar rats submitted to swimming

February 2022

Anxiety is present in several psychiatric disorders, and pharmacological treatment has limitations. Therefore, there is a search for new therapeutic approaches. This study aimed to evaluate the anxiolytic effect of acute administration of the dry extract of Passiflora alata (P. alata) leaves in male Wistar rats submitted to swimming. The animals were randomly divided into four groups (n = 8) (G1 to G4). G2 to G4 were...

Author(s): Airton José Mendes, Annik Ianara de Souza Greco, Renan Santiago Pereira, Wilson Roberto Malfará, Maricelma da Silva Soares de Souza, Sandra Maria Barbalho,, Elen Landgraf Guiguer, and Adriano Cressoni Araujo,  

Ethnobotanical survey of medicinal plants utilized by forest edge communities in southern Sierra Leone

January 2022

A total of 128 medicinal plant species belonging to 71 genera and 46 families were identified and used to treat 42 human ailments. Euphorbiaceae was the leading family with 14 species, followed by Rubiaceae and Leg-Caesalpiniaceae with 12 and 8 species, respectively. Seven species (Coffea stenophylla, Garcinia afzelii, Mitragyna stipulosa, Irvingia gabonensis, Milicia regia, Nauclea diderrichii and Nesogordonia...

Author(s): Jonathan Johnny, Aiah Lebbie and Richard Wadsworth  

Noni essential oil associated with adjuvants in the production of phytoalexins and in the control of soybean anthracnosis

January 2022

Amongst the most important agricultural products in Brazil, the soybean stands out, mainly as an export good. One of the end-of-cycle diseases, Anthracnose, caused by the fungus Colletotrichum truncatum (Schwein.) leads to severe damage to grain quality and yield. The use of natural products as a substitute for conventional pesticides for plant diseases control is an alternative found to reduce food contamination and...

Author(s): Natália Pinto e Nosé, Mateus Sunti Dalcin, Bruna Letícia Dias, Rodrigo Solci Toloy, Dalmarcia Souza Carlos Mourão, Marcos Giongo, Alex Cangussu, Sabrina Helena da Cruz Araújo and Gil Rodrigues dos Santos  

Bioactive small-molecule constituents of Lao plants

December 2021

Laos has a rich plant diversity, and medicinal plants are used extensively in Lao traditional medicine for the treatment of a variety of human diseases. However, only a relatively small number of these plants have been investigated for their major components with potential antitumor, anti-infective, and other types of bioactivities. These species include Asparagus cochinchinensis, Diospyros quaesita, Gongronema...

Author(s): Yulin Ren, Bethany G. Elkington, Joshua M. Henkin, Kongmany Sydara, A. Douglas Kinghorn and Djaja D. Soejarto,  

Optimized flow cytometric protocol and genome size estimation of Sabah snake grass (Clinacanthus nutans)

December 2021

Clinacanthus nutans is an economically important medicinal plant that can be found grown in many countries in the Asian region. Useful medicine properties such as anti-cancer, anti-bacteria, and anti-viral, backed by its high content of phytochemical compounds such vitexin, isovitexin, stigmasterol and lupeol has increased the demand for C. nutans in the market. Extensive work had been carried out on its content and...

Author(s): Vidhyaini Kandaiah, Nallammai Singaram and Kodi Isparan Kandasamy  

Preliminary screening of the antimicrobial activity of nine medicinal plant species from Burkina Faso

November 2021

Infectious diseases, including skin infections, have always been treated by plants and other natural products since ancient times. This study investigated the antimicrobial activity of nine medicinal plant species from Gonsé Forest and Bangreweogo Park, Burkina Faso on seven microbial strains involved in skin infections. Sixty-eight organic and aqueous extracts from leaves, stem and root barks of the nine plants...

Author(s): Ollo Youl, Sibidou Yougbaré, Palpouguini Lompo, Boubacar Yaro, Christian Marc Tahita, Halidou Tinto, Adama Hilou and Maminata Traoré/Coulibaly  

Effects of hydromethanol hypocotyls extract of Borassus aethiopum on sperm and gonadal indices of male Wistar rats

November 2021

Infertility resulting from sperm dysfunction is a serious health problem leading to psychological, economic, and medical implications worldwide. Borassus aethiopum is a plant that has been used as an aphrodisiac. This study evaluated the effect of hydromethanol hypocotyls extracts of B. aethiopum on the sperm and gonadal indices of male Wistar rats. The extract was prepared and administered orally at doses of (250, 500...

Author(s): Mansur A. Ramalan, Adamu B. Shuaibu and Abdullahi H. Yaro  

Ethnobotanical survey on medicinal plants traditionally used for treatment of intestinal parasitosis of animals and humans in Northern Benin

October 2021

Parasitic nematodes of the gastrointestinal (GI) tract remain a major threat to both human beings and livestock. The aim of this study was to document medicinal plants used in the management of intestinal parasitosis in the small ruminants and humans. Information relating to the different plants used in the treatment of human intestinal parasitosis and small ruminants was collected through an ethnobotanical survey...

Author(s): Lissette Houedenou DEGLA, Pascal Abiodoun OLOUNLADE,   Latifou LAGNIKA, Sabbas ATTINDEHOU, Abdou Madjid Olatoundé AMOUSSA, Christian Cocou DANSOU, Basile Saka Boni KONMY, Erick Virgile Bertrand AZANDO, and Sylvie Mawulé HOUNZANGBE-ADOTE  

Phytochemical, elemental and functional group analyses of herbal material and extracts of Cassia sieberiana used in herbal drug formulation

October 2021

Cassia sieberiana is used traditionally for the treatment of several ailments. The lack of knowledge in the levels of essential mineral contents and heavy metal constituents of C. sieberiana normally collected from various sites for preparation of herbal products can pose serious health risks to consumers. The elemental contents (Ca, Mg, K, Na, Cl, Hg, Pb, As, Ni, Cd, Cu, Fe, Mn, Zn, N, S and C) of a mixture of the stem...

Author(s): Mary-Ann Archer, Micheal Odoi Kyene , Doris Kumadoh , Genevieve Naana Yeboah , Frederick Ayertey , Susana Oteng Mintah , Henry Brews-Daniels , Tonny Asafo Agyei , Alfred Ampomah Appiah and Peter Atta-Adjei Jnr  

Comparing checkerboard, isobologram and CCD methods for drug combination: A case study of ciprofloxacin and plant extracts on Escherichia coli and Shigella

October 2021

To investigate the interactive antimicrobial activity of conventional antibiotics, namely ciprofloxacin and Mangifera indica bark ethanol extract, Psidium guajava leaves essential oil against two Gram-negative bacteria using checkerboard, isobologram, and central composite design (CCD) methods. The checkerboard method was used for the determination of the fractional inhibitory concentration index (FICI) value needed for...

Author(s): Gislaine Aurelie KEMEGNE, Sylvain Leroy SADO KAMDEM, Maximilienne Ascension NYEGUE, Chantal MENUT and François-Xavier ETOA  

Protective effect of commercial extracts of oregano (Lippia graveolens) against cardiac ischemia-reperfusion damage

October 2021

Cardiac ischemia includes severe damage to heart muscle tissue due to decreased or cessation of blood flow, which involves failure to supply nutrients and oxygenation to heart cells. Causes can include blockages due to fat and cholesterol deposits. These damages include cell apoptosis, calcium and sodium concentration imbalance, loss of contraction force, and formation of reactive oxygen species. In the present work,...

Author(s): Gabriela Pérez Flores, Jose David Torres Tirado, Ramiro Martínez Acosta, Jorge Alejandro Chávez Aguirre, María Guadalupe Nieto Pescador, Maribel Cervantes Flores, Ashley Stephanie Herrera Godina and Eduardo Lozano Guzmán  

SARS Cov-2 Structure, biology, immunology and clinical course: Exploring the value of traditional medicine in limiting COVID-19 individual risk and disease outcomes

October 2021

Since the onset of COVID-19 in early 2020, various approaches have been adopted worldwide by various state health authorities containing the ravaging pandemic. Tanzania adopted additional approach based on Tanzanian Traditional Medicines. This review aimed to explore the suitability of this local approach based on evaluation of the virus biology, pathogenesis and immunology in relation to the traditional medicines,...

Author(s): Erasto V. Mbugi, Joseph Otieno, Ted Mselle, Sauli E. John, Ruth Boniface, Florence Urio, Baraka S. Mkumbe, Samson Hilonga and Germana H. Leyna  

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