Journal of
Medicinal Plants Research

  • Abbreviation: J. Med. Plants Res.
  • Language: English
  • ISSN: 1996-0875
  • DOI: 10.5897/JMPR
  • Start Year: 2007
  • Published Articles: 3840

JMPR Articles

Development of in vitro protocol for large-scale clonal propagation of Capparis erythrocarpos for the herbal medicine industry and conservation

November 2024

The increased use of Capparis erythrocarpos for treating rheumatoid arthritis and as an appetite stimulant has necessitated the establishment of efficient in vitro propagation protocols for large-scale production of seedlings to ensure its sustainable use in the herbal medicine industry and conservation of the species. In this study, mechanical scarification and priming of seeds with sulfuric and GA3 induced only...

Author(s): Wilfred Elegba, Elaine Azu, James O. Frimpong, Tonny Asafo-Adjei, Peter Atta-Adjei Jnr, Yaw Appau, Seyiram Kumordzie, Kwame Asare and Kenneth E. Danso  

In vitro toxicity, anti-inflammatory and antioxidant activities of ethanolic root extracts of Tanzanian Hydnora abyssinica A. Br. (Aristolochiaceae)

October 2024

Injuries and the effects of diseases, including various types of cancer, are among the sources of inflammation, pain, and discomfort for patients. Hydnora abyssinica, claimed by traditional practitioners in the Eastern Same district to manage inflammation, may contain ingredients with anti-inflammatory activity. This study aimed to evaluate the toxicity and determine the anti-inflammatory and antioxidant activities of...

Author(s): Daniel Z. Matata, Fidelice M. S. Mafumiko, Francis E. Kway, Ernest Prosper, Hussein Yasin, Adam MbugI, Colleen Mrina, Leah Kalinga, Maximilian Mtweve, Jorance Kivuyo, Msafiri Mwasyeba and Hussein Mtenda  

Assessment of the bioavailability of a natural supplement (Storg-HIMmax) against cyclophosphamide-induced immunosuppression models and its effect on in vivo immunomodulation and in vitro antioxidant capacity

August 2024

Bioavailability is an important concept when evaluating natural products for their bioactivities. Therefore, the demand for foods that improve immunity has increased recently. The use of herbal medicine as immunomodulators is so common that it just requires hard scientific evidence to support its effectiveness. In this study, bioavailability, immunomodulatory, and in vitro antioxidant activity of "Storg-HIM...

Author(s): Firoz Hirehal Hussain Mirza and Sadashiva Channangihalli Thimmegowda  

Wound healing effects of Commiphora swynnertonii resin formulations using rat as model animal

July 2024

Commiphora swynnertonii (Burceraceae) is commonly used for the treatment of various ailments, including arthritis, wounds, and skin conditions. In this study, the effects of various formulations of the tree resin on wound healing were evaluated in rats through skin contracture and histological changes. Body weights were also monitored during the experiments. Tree resins were prepared at 0, 2.5, 5, 10, 15, and 30% v/v...

Author(s): James Richard Mushi,  Benigni Alfred Temba, Shaban Mshamu, Robert Arsen Max and Gaymary George Bakari  

Phytochemical profile and quality control of complex herbal mixtures used to prepare slimming drinks, commercialized in Salvador-Bahia, Brazil

May 2024

Traditional herbal products with multiple associated plant species and weight loss claims are widely consumed. The inadequacy of these resources to health standards, the lack of supervision, and the analytical obstacles involved in their investigation are challenges and reasons for this research. In this sense, this study aimed to characterize the profiles: Phytochemical, physical, physicochemical, and microbiological,...

Author(s): Ferdinando Lucas Góis, Danilo Moreira Vilas Boas, Gislane Oliveira Ribeiro, Gildeon Silva Marques, Luciano Morais Lião, Mariângela Vieira Lopes Silva, Ademir Evangelista do Vale and Erika Maria de Oliveira Ribeiro  

Pollen extracts from the Soconusco region: Chemical profile and effect against methicillin-resistant Staphylococcus aureus

May 2024

Pollen has been widely known to have beneficial properties for humans, including fighting harmful microorganisms. On the other hand, bacterial resistance is an obvious global problem that has increased over the years. For this reason, the study of the antimicrobial properties of substances such as pollen could play an important role in this area. The present work focused on evaluating the antimocrobial effect of pollen...

Author(s): Eduardo Lozano Guzmán, Luis Ángel Morán Núñez, Maribel Cervantes Flores, Adolfo Padilla Mendiola, María Guadalupe Nieto Pescador, Gerardo Alfonso Anguiano Vega, Víctor Jesús Albores Flores, Alfonso López García and Julieta Grajales Conesa  

Antioxidant, urobactericidal, and antibiotic modulating activity of a parasitic medicinal plant: Cuscuta reflexa Roxb.

May 2024

The therapeutic potential of age-old Indian herbal remedies needs immediate scientific validation against urogenital problems. This study investigates the antibacterial efficacy of the methanolic extract of Cuscuta reflexa Roxb. stem through multiple diffusion techniques and the zones of inhibition (ZOIs) are expressed in millimeters. The minimum inhibitory concentration (MIC) is found to be 1.25 mg/mL against...

Author(s): S. Rani Tripathy, N. Susmita Pradhan and Sarita Das

In vitro cytotoxic activity of forage peanut (Arachis pintoi Krapov. & W.C. Greg.) oil against leukemic and tumor cell lines

April 2024

Arachis pintoi Krapov. and W.C. Greg. is widely used as forage and displays high seed productivity. Its seed oil contains high levels of phytosterols, mainly β-sitosterol, which has been associated with several biological properties, including cytotoxic activity against different types of cancer. In this study, we investigated the cytotoxic activity of its seed oil against five cancer cell lines using the MTT...

Author(s): Isabela Brandão de Sousa, Girlaine Pereira da Silva, Renata de Oliveira Garcia, Eduardo Fonseca, Katia Costa de Carvalho Sabino, Graça Justo, Georgia Pacheco and Elisabeth Mansur  

Productivity and picroside contents of Picrorhiza kurroa Royle ex Benth. cultivated at multi-locations in Uttarakhand, India

March 2024

Cultivation is cost effective for conservation and sustainable supply of rare and high value medicinal plants. Assessment of productivity and quality testing validates cultivation and improves trade prospective. Picrorhiza kurroa is a recently domesticated Himalayan medicinal herb. Despite, specific habitat preference above 3000 m in natural habitats, P. kurroa is cultivated successfully below 3000 m under diverse...

Author(s): Chandra P. Kuniyal and Rakesh Bisht  

Phytochemical screening and biological activities of Copaifera langsdorffii Desf. (Fabaceae) organic extracts

March 2024

This study explores the therapeutic potential of Copaifera langsdorffii Desf. (Fabaceae), commonly known as Copaíba, a legume renowned for its oleoresin extraction. The organic extracts from Copaíba's leaves, stem bark, and wood, using n-hexane, ethyl acetate and methanol were investigated for their antimicrobial, antioxidant and anti-inflammatory activities. In vitro assessments included determining...

Author(s): Caio Cézar Oliveira de Lucena, Camila Joyce Alves da Silva, Raudiney Frankilin Vasconcelos Mendes, Kêsia Xisto da Fonseca Ribeiro de Sena, Teresinha Gonçalves da Silva and Rafael Matos Ximenes

Comprehensive evaluation of antiacne properties: HPLC analysis of crude extract from Aloe buettneri leaves against Cutibacterium acnes-induced acne

January 2024

The hydroethanolic extract of Aloe buettneri was assessed for its anti-acne activity in a Cutibacterium acnes-induced acne model in rats as part of this study. Conventional therapies for acne often entail serious side effects. Total phenols, quantified using the Folin-Ciocalteu method, were found to be at a concentration of 16 ± 0.3 mg GAE/g, while total flavonoids, determined using the aluminum chloride method,...

Author(s): Affo Dermane, Bignoate Kombate, Kossi Metowogo and Kwashie Eklu-Gadegbeku

Antimicrobial activities of the extract of shea tree (Vitellaria paradoxa Gaertn. F.) leaf and bark on some selected clinical pathogens

December 2023

The use of plants and plant products in the treatment of various ailments has been with humanity since the dawn of time and the potentials of these plants are so enormous that the continuous search for their hidden treasures is more crucial because of the rise in antibiotic resistance. This study was designed to determine the antimicrobial activities of the shea tree (Vitellaria paradoxa) extracts against some selected...

Author(s): Lawrence Adelani Adetunde , Oliver Awo and Abdul-Wahab Mbelayim Imoro

Effects of different nitrogen forms and concentration combinations on American ginseng seedling growth

December 2023

This study investigated the impact of various nitrogen forms on American ginseng (Panax quinquefolius) seedling growth. Thirteen treatments of inorganic and organic nitrogen combinations were tested in the first year and growth indicators were measured. In the second year, treatments with significant growth promotion effects were further verified. The results showed improved growth of American ginseng seedlings when the...

Author(s): Nan Zou, Chongwei Li, Guozhong Chen, Wanxin Huang, Ping Zhu, Yuping Hou and Xinfu Bai  

Phytochemical compounds present in COVI-MXG herbal preparation inhibits RNA-Dependent RNA polymerase from SARS-CoV-2: A molecular docking study

December 2023

Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) has been identified as the agent responsible for COVID-19 pandemic. Currently, no therapeutic agents have proven effective in combating the virus. Managing the infection is mainly palliative in nature, involving infection prevention strategies and supportive therapy anchored on drugs that practitioners have had previous usage experience. Previously exploited...

Author(s): Olanike Catherine Poyi, Kakjing D. Falang and Jacob A. Kolawole  

Qualitative, quantitative composition and evaluation of the antioxidant activity of polar extracts of stem bark of Hexalobus crispiflorus A. Rich (Annonaceae family): Central African species

December 2023

Hexalobus crispiflorus A. Rich., synonym Hexalobus grandiflorus Benth, is a plant in the Central African pharmacopoeia, widely used in the treatment of skin diseases and diabetes. The present study is a contribution to the qualitative and quantitative analysis and evaluation of the antioxidant activity of this plant. Preliminary phytochemical tests carried out on the different crude extracts of H. crispiflorus revealed...

Author(s): Ngaïssona Paul, Worowounga Xavier, Issa-Madongo Mathurin, Komokoïna-Yamadjiyo Arthur Stanislas, Namkona Frédéric Armel, Koane Jean Noël, and Syssa-Magalé Jean-Laurent

Genipa americana fruit ethanolic extract in the control of environmental infecting agents

November 2023

The choice of substances that are not harmful to man and the environment is a priority in the production of sanitizing products. The aim of this study was to evaluate the disinfectant action and biofilm biomass reduction of the ethanolic extract of Genipa americana fruit. The extract disinfectant efficacy was assessed by modified Kelsey-Sykes, solid surface, and use-dilution methods. Also, the ability of the extract to...

Author(s): Paloma Ohana Sousa Abreu, Eanes Pereira De Souza, Luiza Eduarda Costa Silva, Mariana Ely Araujo Oliveira, Fernando Faustino De Oliveira, Rosilene Aparecida De Oliveira, Sandra Rocha Gadelha, Camila Pacheco Silveira Martins Da Mata, Raynah Neves da Hora, Luciana Debortoli de Carvalho and Aline Oliveira da Conceicao  

Ethnobotanical studies in Iran’s rangelands

November 2023

Iran’s rich plant biodiversity includes over 8,400 species, of which more than 2,300 possess medicinal properties. The research community comprised scientific documents on ethnobotany published between 2010 and 2022. Keywords related to ethnobotany, rangeland, and Iran were searched in the databases of scientific journals. All articles were downloaded and read. The collected data were analyzed using Excel. This...

Author(s): Amirreza Heirany and Mahdi Kolahi  

Phytochemicals properties of Carica papaya Linn seeds’ essential oil and their antifungal and antibacterial activities

November 2023

Carica papaya seeds have been used as traditional medicine. This study aims to determine the phytochemicals of papaya seeds essential oils their antimicrobial properties. Polyphenolic content and antioxidant properties were determined with standard methods. GC-MS was used to analyze chemical compounds. Antimicrobial properties were performed using agar diffusion method. MICs, MBCs and MFCs were established based on...

Author(s): OUEDRAOGO Assétou, NIKIEMA Philippe Augustin, YAMEOGO Gérard Josias, SOURABIE Pane Bernadette, BASSAVE Belinda Ramata Hafouo, KONATE Soumaïla, NIKIEMA Marguerite Edith, NIKIEMA Oueogo, GOUMBRI Wendinmi Bertrand Florent and BARRO Nicolas  

Medicinal plants diversity at King Salman Bin Abdulaziz Royal Natural Reserve in Saudi Arabia and their conservation management

November 2023

King Salman Bin Abdulaziz Royal Natural Reserve (KSRNR) is the largest protected area in the Middle East. This literature review study considered the primary survey on the native medicinal plant diversity at KSRNR in the Kingdom of Saudi Arabia (KSA). KSRNR flora, until now, has about 260 plant species, representing about 12% of the KSA flora. Information was gathered through an extensive literature survey, which...

Author(s): Hatem A. Shabana, Tamer Khafaga, Hamdan Al-Hassan and Shaykah Alqahtani  

Determination of tetrahydrocannabinol and cannabidiol contents in Cannabis sativa L. samples in Togo using gas chromatography-mass spectrometry

October 2023

Cannabis sativa L. is a widely used recreational drug in Togo, especially among young people. However, little is known about its chemical composition in Sub-Saharan Africa, and specifically in Togo. This study aimed to determine the levels of phytocannabinoids, specifically Δ9-tetrahydrocannabinol (THC) and cannabidiol (CBD), in cannabis samples collected from various towns in Togo using gas chromatography coupled...

Author(s): Kodjo Eloh, Komi Alfa, Oudjaniyobi Simalou, Sabrina Chris Janiba SANVEE , Marie-France Bakaï, Hèzouwè Kagnou and Pierluigi Caboni  

Effect of Canarium schweinfurthii leaf and pulp extracts on blood glucose levels in oral glucose load - induced hyperglycemia in Wistar albino rats

September 2023

Canarium schweinfurthii is a common medicinal plant used as food and medicine in communities of central Uganda. Local communities and herbalists commonly used it in the management of diabetes mellitus type 2 with limited information on its effectiveness.  Study assessed the hypoglycemic effect of C. schweinfurthii aqueous and total crude leaf and pulp extracts on blood glucose levels in Wistar albino rats. An...

Author(s): Kyewalabye J. C., Kasolo J. N., Lugaajju A., Kirenga B., Batte C., Lubega A. and G. S. Bbosa  

Comprehensive liquid chromatography-mass spectrometry-based metabolomic analysis of Moringa oleifera seeds

September 2023

Moringa oleifera seeds which are less explored and nutriment-rich have attracted scientific interest as the seed kernels contain numerous bioactive components with a variety of traditional uses. Besides its medicinal uses, Moringa oleifera biodiesel has shown remarkable potentiality in conducing to the decrease of greenhouse gases and guaranteeing sustainable supply of energy. In this study, the comprehensive analysis...

Author(s): Famurewa Oluwayemisi Juliannah, Istifanus Yarkasuwa Chindo and Auwal Adamu Mahmoud  

Chemical characterization of bottlebrush leaves found in NISLT premises, Samonda, Ibadan, Nigeria.

August 2023

This study investigated the chemical composition of Bottlebrush leaves for its ascribed mythical medicinal uses. Bottlebrush leaves were collected from the Nigerian institute of science laboratory technology premises in Ibadan, Nigeria. Proximate analyses, phytochemical screening, elemental analysis and antioxidant analysis were carried out on the leaves extract. This study has provided a scientific justification that...

Author(s): Murtala M., Imohiosen, J. J., Idenyi E. O., Aribo T. O., Gbadegesin Y. E., David B. and Ikokoh, P. P. A.  

Pre-sowing treatments to improve seed germination and seedling growth of Commiphora swynnertonii (Burrt.) and Synadenium glaucescens (Pax.)

July 2023

Medicinal and pesticidal plant propagation is hampered by poor seed germination due to seed dormancy. This study aimed to enhance seed germination and seedling growth using various pre-sowing treatments. A triplicated two-factor experiment in a Randomized Complete Block design was used. Soaking in water at 25°C for 24 h (T1), soaking in 60°C hot water for 10 min (T2), 10 ppm Potassium nitrate (KNO3) treatment...

Author(s): Madege Richard Raphael, Babu Saidi, Mabiki Faith Philemon, Hosea Mtui and Abdul Kudra  

Inhibition and dissolution of calcium oxalate crystals and kidney stones by the extract of Kalanchoe pinnata

June 2023

Kalanchoe pinnata leaves are used in South Asia as a natural kidney stone treatment. In vitro studies were conducted in supersaturated and artificial urine solutions to evaluate the antiurolithic properties of K. pinnata leaf extract on calcium oxalate monohydrate (COM) and surgically extracted kidney stones. Key organic acids present in the plant extract were also examined in artificial urine to investigate inhibition...

Author(s): Samantha Ranaweera, Shanika Weerasinghe, Fatema Tarannum and Keisha B. Walters  

Anti-inflammatory effect of chaya extracts fractions

June 2023

Patients with Type 2 diabetes often experience chronic inflammation due to the overexpression of NF-kB-regulated pro-inflammatory proteins, such as TNF-alpha, IL-6 and IL-1. Chaya (Cnidoscolus aconitifolius) extracts have been reported to decrease this expression, but fractions of these extracts have not been studied. The present work focused on determining the anti-inflammatory effect of fractions of aqueous extracts...

Author(s): Eduardo Lozano Guzmán, Ashley Stephanie Herrera Godina, Maribel Cervantes Flores, María Guadalupe Nieto Pescador, Adolfo Padilla Mendiola and Ángel Antonio Vértiz Hernández

Evaluation of catechin, lupeol, and betulinic acid as markers for the chromatographic quality Control of Albizia coriaria raw materials; an experimental study

May 2023

Albizia coriaria stembark is among the most common raw materials used to manufacture herbal products in Uganda. While the plant material is sourced from the wild, there are neither monographs nor chemical analytical methods for its standardisation. In addition, good cultivation, harvesting, and manufacturing practices are not mandatory. This leads to inconsistent quality of raw materials and products. This work...

Author(s): Bruhan Kaggwa, Edson Ireeta Munanura, Henry Kyeyune, Godwin Anywar, Hedmon Okella, Clement Olusoji Ajayi, Raphael Wangalwa, John Mulangwa, Crispin Duncan Sesaazi, Lynn K. Bagoloire, Casim Umba Tolo, Pakoyo Fadhiru Kamba and Patrick Engeu Ogwang

Palyno-morphological assessment of Asteraceae taxa grown in Qarshi Botanical garden at Qarshi Industries (Pvt.) Ltd by using LM and SEM, Pakistan

May 2023

The present study covers the micro-morphological characteristics of 32 taxa of Asteraceae family from Qarshi Botanical Garden at Qarshi Industries (Pvt.) Ltd., Hattar Haripur, Pakistan. The morpho-palynological characters studied were size, shape, polar and equatorial diameter and their exine ornamentation using light microscopy (LM) and scanning electron microscopy (SEM) for its taxonomic significance. In the present...

Author(s): Siraj Khan,, Sohail Anwer,, Muhammad Rashid,, Majid Iqbal, and Shabeer Ahmad,    

Citrullus lanatus plant response to irrigation water magnetized in sandy soil

May 2023

In this study, the productivity of the red watermelon (Citrullus lanatus) crop in arid regions with saline water is examined in relation to the effects of magnetic treatment of irrigation water. The greenhouse experiments compared two treatments (magnetic treatment of irrigation water) and (no magnetic treatment of irrigation water). Magnetic treatment device delta water with a power of 14500 gausses (1.45 T) that was...

Author(s): Djilani GHEMAM AMARA, Hacene LAOUEDJ, Ahmed Elkhalifa CHEMSA, Khaled KHERRAZ, Said TOUATI, Zeïd ALIA, TOUATIHAMAD larouaci, Ahmed IBEDand Hamza BOUGRINAT  

HPLC determination of polyphenols of the flowers of Digitalis lamarckii, Xeranthemum annuum, Epilobium hirsutum and Silene compacta from Bolu (Turkey)

May 2023

There have been a growing interest since decades in the medicinal plants in terms of preventive health care and treatment of various diseases. On the other hand, polyphenolic compounds present in medicinal plants are known to have antioxidant potency. In the current work, the quantitative HPLC analysis of the flowers of four plants grown in Bolu-Turkey, Silene compacta, Digitalis lamarckii, Xeranthemum annuum L., and...

Author(s): Nedime Dürüst, Yasar Dürüst, Nursel Ikinci, Seray Banko, Emir Zafer Hosgün and Berrin Bozan

Sedative and hypnotic effects of the compatibility of Schisandra chinensis and Polygala tenuifolia on insomnia mice

May 2023

The objective of this study is to study the sedative and hypnotic effects of the compatibility of Schisandra chinensis (SC) and Polygala tenuifolia (PT) on insomnia mice and its mechanisms. The 160 SPF KM mice were divided into 8 groups with 20 each group (10 female and 10 male mice), including control, model, estazolam, SC, PT, SC-PT 1:1, SC-PT 1:2, and SC-PT 2:1 group. Insomnia mice model was established with...

Author(s): Haifeng Sun, Han Wang, Na Li and Hongyu Yang  

Phytochemical screening, anti-inflammatory and immunomodulatory activities of Acanthospermum hispidum and Croton zambesicus collected in the Republic of Benin

April 2023

This study aims to characterize chemical groups of metabolites in extracts of Acanthospermum hispidum and Croton zambesicus, and to evaluate their anti-inflammatory activities and their immunomodulatory effect on two pro-inflammatory cytokines (TNFα and IL6). The phytochemical screening was done on the powders of both plants by staining and precipitation reactions. Anti-inflammatory activity was performed in vivo...

Author(s): Paulin Kpodji, Gatien Lokossou, Victorien Dougnon, Phénix Assogba, Alidehou Jerrold Agbankpé, Esther Déguénon, Gérardo Agbaka, Expédit Yéhouénou, Tatiana Hountohotègbè, Jean-Robert Klotoé, Kévin Sintondji and Lamine Baba-Moussa

Amazonian andiroba oil (Carapa guianensis Aubl.) minimizes the formation of postoperative adhesions in the uterus and ovaries of sheep

March 2023

Postoperative adhesions (POA) are postsurgical fibrinolytic connections that can cause complications, and alternative materials have drawn attention to their prevention. The aim of this study is to evaluate the effect of andiroba oil in preventing POA in the uterus and ovaries of sheep. Sixteen female Santa Inês adult sheep were randomly divided into two groups, a control group (CCG) with eight of them submitted...

Author(s): Francisco Monteiro, Adriana Barbosa, Gabriela Santos, Daniella Bezerra, Luisa Borges, Luciana Siqueira, Kayan Rossy, Rodrigo Albuquerque, Thiago Cardoso, Carolina João and Pedro Paulo Teixeira  

Effects of millet on calcium oxalate crystal growth and dissolution

March 2023

The influence of aqueous extract of millet on the crystallization and the dissolution of calcium oxalate (CaOx) crystals were investigated in detail under supersaturated and artificial urinary circumstances in order to understand the effect of the water-soluble components of millet on CaOx kidney stones in humans. To investigate the inhibition effect, different volumes of millet extract were added separately to the...

Author(s): Samantha A. Ranaweera, Vindya U. Liyanagamage and Mark G. White  

In vivo hypotensive activity on the albino’s rat and in vitro antioxidant activities of aqueous extract from Guibourtia tessmannii (Harms) J. Leonard (Cesalpiniaceae) stem barks

March 2023

In Central Africa, stem bark from Guibourtia tessmannii is used in traditional pharmacopeia for the treatment of hypertension. The aim of this study was to scientifically verify the traditional use in the treatment of metabolic pathologies such as arterial hypertension and evaluated its pharmacological potential. Phytochemical tests were evaluated by standard method of laboratory. Antioxidant activities were determined...

Author(s): Noreen Orianna Koumba Madingou, Patrice Soulounganga, Jean Alban Ondh-Obame, Gontran Nsi, Alain Souza, Aristide Traoré and Alfred Sababenedyo Traoré  

Phytochemical screening and gas chromatography-mass spectrometry analysis of Euphorbia ingens organic root extract

March 2023

Euphorbia ingens is a woody, succulent tree with ethnomedicinal applications; however, its chemical constituents are not well documented. This study determined the phytochemical profile of Euphorbia ingens dichloromethane-methanol root bark extract. Following sample collection and preparation, extraction was done using the cold percolation technique. This was followed by qualitative phytochemical screening and gas...

Author(s): Innocent Oluwaseun Okpako, Florence A. Ng’ong’a, Mutinda C. Kyama and Sospeter N. Njeru  

Evaluation of antibiotic efficacy of Ocimum gratissimum L. essential oil against Staphylococcus aureus and Pseudomonas aeruginosa

February 2023

Ocimum gratissimum essential oil (EOGT) has been evaluated for its antibacterial efficacy, and its combinational therapy with antibiotics may enhance the therapeutic efficiency against infection-causing bacteria. Herein, we evaluated the chemical composition of EOGT and its antibiotic efficacy against Staphylococcus aureus and Pseudomonas aeruginosa. GC-MS and GC-FID analyzed EOGT. The antibiotic efficacy was determined...

Author(s): Leonardo de Paiva Belo, Flávia Costa de Moraes, Celia Hitomi Yamamoto and Orlando Vieira de Sousa

In-vitro assessment of antibacterial effects of combined crude extracts of S. glaucescens and C. swynnertonii with antibiotics

February 2023

Currently, there is an upsurge of bacterial resistance in single-drug treatment regimens. This has stimulated a growing interest in research and development of new antibacterial agents containing several ingredients as one of the means to combat bacterial resistance. Herb-antibiotic combination therapy is one of the reported effective treatment regimens to combat antimicrobial resistance. This study was aimed to assess...

Author(s): Mary George Ochollah, Faith Philemon Mabiki, Lughano Jeremy Moses Kusiluka, Robinson Hammerthon Mdegela and John Elmerdahl Olsen  

Traditional knowledge of plants used against upper respiratory tract affections in the Littoral Region of Cameroon

February 2023

Traditional medicine is used by people as an alternative to orthodox drugs to treat respiratory infections. The aim of this research was to document traditional recipes used in the treatment of upper respiratory tract infections such as pharyngitis, cold, and sinusitis in peri-urban and rural areas of the Littoral Region of Cameroon. Ethnobotanical surveys were carried out using semi-structured interview model in French...

Author(s): Ngotta Biyon Jacques Bruno, Doumbe Makembe Lea Clémence, Nnanga Jeanne Flore, Mvogo Ottou Patrice Brice, Nguimfack Dongmo Jasmine and Ndongo Din  

Pachyrhizus toxicity: Genetic variability of mature and immature seeds and its effects on Sclerotium rolfsii and Ralstonia solanacearum

January 2023

Pachyrhizus seeds-induced toxicity is very well-known to have developed in humans, fishes, insects, and some micro-organisms. Yet, there is a paucity of studies addressing it in their germplasm, as well as its effects on some phytopathogens. This work aimed to assess the Pachyrhizus genetic variability on toxicity and to determine Pachyrhizus extract toxicity on Sclerotium rolfsii and Ralstonia solanacearum in vitro. In...

Author(s): Thiago MP e Silva, Rândrea GV Guimarães, Anne KB Martins, Danilo F Silva Filho and César A. Ticona-Benavente  

Bioprospecting of the antifungal activity of Patchouli essential oil (Pogostemon cablin Benth) against strains of the genus Candida

January 2023

The incidence of infections caused by Candida has increased worldwide and these strains are becoming resistant to their respective drugs, requiring the search for new drugs with greater efficacy and safety. Natural products are an alternative means of treatment. The essential oil (EO) stands out among these products, due to some biological activities relevant to human health, including antibiotic and antifungal...

Author(s): Da Cunha S. M. D., Alves C. A., Ribeiro L. S. M., Macedo M. A., Da Silva A. L. S., Cunha F. N., De Lima B. V. S. L., Silva D. F., Lima E. O. and De Oliveira Filho  

Valuation study on the extracts of Ilex guayusa Loes. as an antioxidant and anti-aging raw material

January 2023

Ilex guayusa Loes. is a medicinal plant used by people of the Ecuadorian Amazon for treating various diseases and for its stimulating properties. In recent years, several studies have shown this plant to possess a high concentration of phenolic compounds and a high antioxidant potential, allowing it to be used as an ingredient for cosmetic formulations. This research confirms the presence of phenolic compounds between...

Author(s): Paco Noriega, Christian Larenas, Alba Nadal, Ricardo Fonseca, Mishell Silva, Lissette Calderón and Tatiana Mosquera,  

Medicinal plants for the treatment of malaria and typhoid diseases

January 2023

The review concentrated on current literature on medicinal plants for the treatment of malaria and typhoid related diseases, highlighting information about their ethnobotany. The entire plants reviewed showed strong activities, establishing their different traditional applications and capability to control or eliminate malaria and typhoid diseases. Malaria and typhoid diseases are the most problematic public health...

Author(s): Olusola, L. F., Baba, J. and Muhammad, I. L  

Antiedematogenic activity of Petiveria alliacea L. in bothropic poisoning

December 2022

The biodiversity of the Brazilian biomes inspires interest in research about the biological activities of the molecules present in the flora. In this line, Petiveria alliacea a common plant species in the savanna of Tocantins, reported in the treatment for snakebites, was studied to analyze the phytochemical profile and evaluate the activity on the edema caused by Bothrops moojeni snake venom. A qualitative...

Author(s): Marcio Trevisan, Patricia Siqueira de Melo Rodrigues, Antônio Ítalo dos Santos Nunes, Milena Dos Santos Falcão, Hemilly Cirqueira Martins, Elisandra Scapin, Marcio Galdino Dos Santos and Carla Simone Seibert  

Determination of total phenolic and flavonoid content, antioxidant and cytotoxic activity of the methanol extract of Acacia nilotica pods

December 2022

Acacia nilotica is a medicinal plant used in Niger republic for the treatment of gastrointestinal diseases. The aim of this study was to investigate total phenolic and flavonoid content, antioxidant and cytotoxic activity of the A. nilotica pods collected from Niger republic. The phytochemical contents were examined by colorimetric methods. Antioxidant activity of the methanol extract was screened using DPPH, ABTS and...

Author(s): Maman Manzo Lawaly, Khalid Ikhiri and Liu Yu  

Phytochemical study and anti-radical activity of extracts from the oil seeds of Desbordesia glaucescens (Engl.)Tiegh. from Gabon

November 2022

The report focused on the extraction of oilseeds of Desbordesia glaucescens (Engl.) Tiegh. from Gabon as well as on the phytochemical study and evaluation of the anti-free radical activity of the extracts obtained. The extraction was carried out by cold maceration with solvents of increasing polarities: hexane, tricholroethylene, acetone, ethanol and distilled water. The anti-free radical activity was measured by...

Author(s): Medza M’Ella Darina Livia, N’Negue ép Mezui-Mbeng Marie Andrée, Edou Engonga Prosper, Mengome Line Edwige, Engone Obiang Nestor, Aboughe-Angone Sophie

Ethnobotanical survey and phytochemical screening of aqueous extracts from Detarium microcarpum Guill. & Perr in Mali

October 2022

Detarium microcarpum Guill. & Perr is a tree which belongs to Caesalpiniacea family and can reach up 10 m of height, with a horizontal root system. It is confined to the arid regions of West and Central Africa, where it mainly occurs in savannah. The aim of this work is to collate information on the use of Detarium microcarpum in folk medicine by traditional health practitioners and herbalists. Moreover, a...

Author(s): N. Dembele, A. A. Somboro, M. Badiaga, S. Cisse, M. Cisse, I. Togola, P. Nick and N. Traore

Aqueous extracts of Lentinula edodes, Pleurotus pulmonarius, and Pleurotus sajor-caju: Antifungal activity and inhibition of exoenzyme production by Candida albicans

October 2022

This study was aimed at evaluating the effects of aqueous extracts of Lentinula edodes (SHI), Pleurotus pulmonarius (PUL), and Pleurotus sajor-caju (PSC) on the growth of eight yeast species and the exo-enzyme production by Candida species after exposure to the extracts, which were prepared with the cold extraction methodology and tested against yeasts by the broth microdilution method. Proteinase and phospholipase were...

Author(s): Morgana Lüdtke Azevedo, Carolina Lambretch Gonçalves, Alessandro Menna Alves, Caroline Neugebauer Wille, Adriana Etges, Patrícia da Silva Nascente, and Rafael Guerra Lund,  

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