Journal of
Medicinal Plants Research

  • Abbreviation: J. Med. Plants Res.
  • Language: English
  • ISSN: 1996-0875
  • DOI: 10.5897/JMPR
  • Start Year: 2007
  • Published Articles: 3761

JMPR Articles

Effects of hydromethanol hypocotyls extract of Borassus aethiopum on sperm and gonadal indices of male Wistar rats

November 2021

Infertility resulting from sperm dysfunction is a serious health problem leading to psychological, economic, and medical implications worldwide. Borassus aethiopum is a plant that has been used as an aphrodisiac. This study evaluated the effect of hydromethanol hypocotyls extracts of B. aethiopum on the sperm and gonadal indices of male Wistar rats. The extract was prepared and administered orally at doses of (250, 500...

Author(s): Mansur A. Ramalan, Adamu B. Shuaibu and Abdullahi H. Yaro  

Preliminary screening of the antimicrobial activity of nine medicinal plant species from Burkina Faso

November 2021

Infectious diseases, including skin infections, have always been treated by plants and other natural products since ancient times. This study investigated the antimicrobial activity of nine medicinal plant species from Gonsé Forest and Bangreweogo Park, Burkina Faso on seven microbial strains involved in skin infections. Sixty-eight organic and aqueous extracts from leaves, stem and root barks of the nine plants...

Author(s): Ollo Youl, Sibidou Yougbaré, Palpouguini Lompo, Boubacar Yaro, Christian Marc Tahita, Halidou Tinto, Adama Hilou and Maminata Traoré/Coulibaly  

Studies of the anti-hyperglycemic and antioxidant activities of the extract of aerial yam (Dioscorea bulbifera)

October 2021

This study investigated the anti-hyperglycemic and antioxidant activities of methanol extract of Dioscorea bulbifera with a view to studying the possibility of utilizing the yam in the management of hyperglycemia. Methanol extracts of the peels (MEPL), fresh (MEFL), and the whole tuber (MEWT) were prepared, phytochemically screened and assayed for α-amylase. Hyperglycemia was induced in rats using intraperitoneal...

Author(s): Kelechi Nkechinyere Akinyele, Beatrice Oluyomi Emma-Okon, Adeniyi Oluwadare Fajobi, Adetoun Elizabeth Morakinyo and Oluboade Oluokun Oyedapo  

Phytochemical, elemental and functional group analyses of herbal material and extracts of Cassia sieberiana used in herbal drug formulation

October 2021

Cassia sieberiana is used traditionally for the treatment of several ailments. The lack of knowledge in the levels of essential mineral contents and heavy metal constituents of C. sieberiana normally collected from various sites for preparation of herbal products can pose serious health risks to consumers. The elemental contents (Ca, Mg, K, Na, Cl, Hg, Pb, As, Ni, Cd, Cu, Fe, Mn, Zn, N, S and C) of a mixture of the stem...

Author(s): Mary-Ann Archer, Micheal Odoi Kyene , Doris Kumadoh , Genevieve Naana Yeboah , Frederick Ayertey , Susana Oteng Mintah , Henry Brews-Daniels , Tonny Asafo Agyei , Alfred Ampomah Appiah and Peter Atta-Adjei Jnr  

SARS Cov-2 Structure, biology, immunology and clinical course: Exploring the value of traditional medicine in limiting COVID-19 individual risk and disease outcomes

October 2021

Since the onset of COVID-19 in early 2020, various approaches have been adopted worldwide by various state health authorities containing the ravaging pandemic. Tanzania adopted additional approach based on Tanzanian Traditional Medicines. This review aimed to explore the suitability of this local approach based on evaluation of the virus biology, pathogenesis and immunology in relation to the traditional medicines,...

Author(s): Erasto V. Mbugi, Joseph Otieno, Ted Mselle, Sauli E. John, Ruth Boniface, Florence Urio, Baraka S. Mkumbe, Samson Hilonga and Germana H. Leyna  

Comparative study of wild chamomile plants from the north-west of Morocco: Bioactive components and total antioxidant activity

October 2021

Morocco presents numerous plants due its localization between the Mediterranean Sea and Atlantic Ocean and the variability of its mountainous terrain, with a rich range of medicinal plants. Cladanthus mixtus (L.) Oberpr. & Vogt and Matricaria chamomilla L., two Asteraceae (Compositae) from Beni Hassane region in north-western Morocco are both used in traditional medicine for the treatment of different ailments. The...

Author(s): Amina EL MIHYAOUI, María Emilia Candela CASTILLO, Antonio CANO, Josefa HERNANDEZ-RUIZ, Ahmed LAMARTI and Marino Bañon ARNAO  

Comparing checkerboard, isobologram and CCD methods for drug combination: A case study of ciprofloxacin and plant extracts on Escherichia coli and Shigella

October 2021

To investigate the interactive antimicrobial activity of conventional antibiotics, namely ciprofloxacin and Mangifera indica bark ethanol extract, Psidium guajava leaves essential oil against two Gram-negative bacteria using checkerboard, isobologram, and central composite design (CCD) methods. The checkerboard method was used for the determination of the fractional inhibitory concentration index (FICI) value needed for...

Author(s): Gislaine Aurelie KEMEGNE, Sylvain Leroy SADO KAMDEM, Maximilienne Ascension NYEGUE, Chantal MENUT and François-Xavier ETOA  

Protective effect of commercial extracts of oregano (Lippia graveolens) against cardiac ischemia-reperfusion damage

October 2021

Cardiac ischemia includes severe damage to heart muscle tissue due to decreased or cessation of blood flow, which involves failure to supply nutrients and oxygenation to heart cells. Causes can include blockages due to fat and cholesterol deposits. These damages include cell apoptosis, calcium and sodium concentration imbalance, loss of contraction force, and formation of reactive oxygen species. In the present work,...

Author(s): Gabriela Pérez Flores, Jose David Torres Tirado, Ramiro Martínez Acosta, Jorge Alejandro Chávez Aguirre, María Guadalupe Nieto Pescador, Maribel Cervantes Flores, Ashley Stephanie Herrera Godina and Eduardo Lozano Guzmán  

Ethnobotanical survey on medicinal plants traditionally used for treatment of intestinal parasitosis of animals and humans in Northern Benin

October 2021

Parasitic nematodes of the gastrointestinal (GI) tract remain a major threat to both human beings and livestock. The aim of this study was to document medicinal plants used in the management of intestinal parasitosis in the small ruminants and humans. Information relating to the different plants used in the treatment of human intestinal parasitosis and small ruminants was collected through an ethnobotanical survey...

Author(s): Lissette Houedenou DEGLA, Pascal Abiodoun OLOUNLADE,   Latifou LAGNIKA, Sabbas ATTINDEHOU, Abdou Madjid Olatoundé AMOUSSA, Christian Cocou DANSOU, Basile Saka Boni KONMY, Erick Virgile Bertrand AZANDO, and Sylvie Mawulé HOUNZANGBE-ADOTE  

Therapeutic applications of Caryocar brasiliense: Systematic review

September 2021

The interest and search for natural active principles with therapeutic properties from plants are growing, given their potential for use by the cosmetic and pharmaceutical industries. Thus, the objective of this review was to carry out a systematic analysis of scientific productions that have explored some therapeutic potential of Caryocar brasiliense. The methodology of the preferred reporting items was adopted for...

Author(s): Fábio Fernandes Bruno Filho, Wanessa Ferreira Ataíde, Mônica Rodrigues Ferreira Machado, Ariel Eurides Stella, Liliane Nebo, Sandra Aparecida Benite-Ribeiro, Frederico Augusto Guimarães Guilherme and Andréia Vitor Couto do Amaral

Effect of n-hexane extract of baobab (Adansonia digitata) fruit on biochemical parameters of l-ng-nitro arginine methyl ester induced hypertension in rats

September 2021

L-NG-Nitro arginine methyl ester (L-NAME) was used to induce hypertension in this experiment and the intervention plant extract was Adansonia digitata fruit. A total of 30 rats were used for this research and divided into 6 groups of 5 animals each. Group 1 was control (water and feed ad libidum), group 2 (L-NAME), group 3 (ramipril 10 mg/kg), group 4 (A. digitata 200 mg/kg), group 5 (A. digitata 400 mg/kg) and group 6...

Author(s): Ediale Joshua Richard, Innocent Abi and Olasupo Stephen Adeniyi

Piper multinodum C.DC. (Piperaceae) essential oils chemical variation and biological activity against Mycobacterium tuberculosis

September 2021

Piper multinodum C.DC. belongs to the Piperaceae family, and is known as “Jaborandi-manso”. This species has no reported botanical, chemical, pharmacological and/or toxicological scientific studies, and has restricted occurrence in degraded Brazilian biomes. The Piper genus is known to be aromatic, the essential oils (EO) obtained from different organs have demonstrated significant biological activities, and...

Author(s): Ygor Jessé Ramos,, Claudete Costa-Oliveira, Irene Candido Fonseca, Diego da Silva Marcelino, Marlon Heggdorne-Araujo, Elena B. Lassounskaia, Michelle F. Muzitano, George A. Queiroz, Elsie F. Guimarães and Davyson de Lima Moreira,

Chemical investigation, toxic potential and acetylcholinesterase inhibitory effect of Parkia platycephala leaf and seed extracts

September 2021

The present work evaluated the inhibitor potential of acetylcholinesterase, the preliminary toxicity and determination of active components of different leaf and seed extracts of Parkia platycephala. All extracts were obtained through hot extraction in a closed system (Soxhlet). To obtain the leaf and seed hexanic, methanolic, and ethanolic extracts (LHE, LME, LEE, and SHE, SME, and SEE), sequential extraction was...

Author(s): Rachel de Moura Nunes Fernandes, Maria Angelica Melo Rodrigues, Juliane Farinelli Panontin, Daniela Ribeiro Alves, Selene Maia Morais, Ilsamar Mendes Soares  and Elisandra Scapin..

Composition and antioxidant potential of leaf and stem essential oils from Nigerian Indigofera spicata Forssk

September 2021

The chemical compositions and antioxidant evaluation of the essential oils (EOs) obtained by hydrodistillation from the leaf and stem of Indigofera spicata Forssk (Fabaceae) grown in Nigeria have been studied. The EOs were analyzed using gas chromatography coupled with mass spectrometry (GC-MS) and the antioxidant potential was determined using 2,2-diphenyl-1-picrylhydrazyl (DPPH) free radical scavenging ability method....

Author(s): Temitope Adewumi Adeleye, Clement Odunayo Ajiboye, Emmanuel Onah Ojah, Toyin Patrick Okesanjo and Dorcas Olufunke Moronkola

Comparative studies of antioxidant and anti-inflammatory potentials of ethanolic leaf extract of Sorghum bicolor and Zea mays

August 2021

This study was designed to investigate the anti-inflammatory and anti-oxidant potentials of leaf extracts of Zea mays (maize) and Sorghum bicolor (sorghum) with a view of utilizing them as herbal tea on the management and treatment of oxidant and inflammatory disorders. The powdered plant materials: (Z. mays, (30 g), S. bicolor (30 g), mixture (15 g of Z. mays + 15 g of S. bicolor) were soaked separately in 80% (v/v)...

Author(s): Morakinyo Adetoun Elizabeth, Salawudeen Hammed Opeyemi and Oyedapo Oluokun Oluboade

Traditional Chinese medicine Zizhu ointment alleviates inflammatory activity during wound healing in diabetic rats

August 2021

Diabetic ulcers are a severe complication in patients with diabetes that often lead to amputation. The etiology of diabetes-induced wound healing impairment is multi-faceted. Persistent inflammation and deficient tissue regeneration have been suggested to impair wound healing in diabetes patients. Although new therapeutic approaches have been developed, many chronic wound treatments remain unsatisfactory, and more...

Author(s): Qiang Han, Liang Qin, Xiao Yang, Renyan Huang, Xiaoming Hu, Wenhui Li and Guobin Liu

Chemical characterization and toxicological analyses of hydroalcoholic extracts from the stem and leaves of mangabeira (Hancornia speciosa Gomes) as a guide for the development of green cosmetics

August 2021

The increasing interest in green cosmetics has a major influence on the cosmetics market, whether due to the incorporation of the functionalities of the extracts, or the substitution of synthetic ingredients with natural ones. Yet, the natural substances found in those products must be evaluated for their chemical characterization and toxicity. This study determined the chemical profile and assessed the toxicity of stem...

Author(s): Juliane Farinelli Panontin, Rafaela Pereira Neres, Rachel de Moura Nunes Fernandes, Elisandra Scapin, and Carla Simone Seibert

Assessment of minimum growth conditions for in vitro conservation of Passiflora edulis Sims

August 2021

Passiflora edulis Sims, besides having economic and social importance, is included in the medicinal plant list that is considered of interest by the Unified Health System (Sistema Único de Saúde – SUS). Due to its high nutritional value, this species is widely used in food, cosmetics and pharmaceutical industries. It also contains carotenoids, as well as passiflorine and maracugine, which have...

Author(s): Manuella Silva Oliveira Souza, Eldo Ciano da Silva, Gabriella Silva Oliveira Souza Ciano, Claudia Cecilia Blaszkowski de Jacobi, Josemário Santana Bonsucesso, Weliton Antonio Bastos de Almeida and Mariane de Jesus da Silva de Carvalho

Effects of Boswellia serrata, Zingiber officinale and Ginkgo biloba extracts in combination on memory impairment in mice

July 2021

Cognitive decline induced by oxidative brain damage is the critical pathological hallmark of Alzheimer’s disease. Studies have shown that individual administration of Boswellia serrata Roxb (BS), Zingiber officinale Roscoe (ZO) and Ginkgo biloba L. (GB) extracts improved memory and learning through a different mechanism of actions. This study aims to compare the individual effects of each extract with their...

Author(s): Arsalan Moradian, Masoud Sadeghi Dinani, Ali Hosseini Sharifabad and Mohammad Rabbani

Analysis by GC (Ir), GC/MS and mosquito repellent effect of essential oils against Anopheles gambiae: Case of stem bark of Sterculia tragacantha Lindl (Sterculiaceae) from Côte d'Ivoire

July 2021

The objectives of this study were to determine the chemical composition and to evaluate the mosquito repellent property of essential oils extracted from the bark of the stem of Sterculia tragacantha Lindl on Anopheles gambiae, vector of malaria. The essential oil of the stem bark of S. tragacantha Lindl is extracted by hydrodistillation and their chemical compositions were identified by GC (Ir) and GC-MS. This oil has...

Author(s): Sahi Zlankeuhon Jerome, Boua Boua Benson, Ouattara Allassane Foungoye, Mamyrbekova-Bekro Janat Akhanovna and Bekro Yves-Alain

Study of seasonality and location effects on the chemical composition of essential oils from Eugenia uniflora leaves

July 2021

The essential oils of Eugenia uniflora leave possess several biological activities but a great variability in their chemical composition is observed. In the present study, gas chromatography and mass spectrometry were applied to examine the essential oil from leaves of four different specimens over the seasons of the year, two of which are located in a habitat of a Brazilian metropolis, and the other two in a natural...

Author(s): Gonçalves Adilson Júnior, Eutimio G. Fernández Núñez, Renata O. Santos, Bryna T. Haraki Otaviano, Rosely L. Imbernon, Fabiana C. Pioker, Marcelo J. Pena Ferreira and Miriam Sannomiya

Metabolic profile of wistar rats after consumption of flour prepared with grains and fruits

July 2021

The occurrence of chronic and degenerative diseases, such as obesity, diabetes, cardiovascular disease (CVD), and cancer is increasing sharply. In the last years, there has been an increase in interest in the consumption of foods with functional properties that are related to weight loss and disease prevention. For these reasons, this study aimed to evaluate the effects of flour prepared with grains and fruits on the...

Author(s): Barbara Bucalem, Barbara Geraldo Amaro, Bruna Gomes Prado, Julia Novacki, Sandra Maria Barbalho, Élen Landgraf Guiguer, Maricelma da Silva Soares de Souza, Manuela dos Santos Bueno, Adriano Cressoni Araújo and Patrícia Cincotto dos Santos Bueno,

Pachyrhizus spp. seed extracts control the Sclerotium rolfsii Sacc. mycelial growth

July 2021

The present paper aimed to characterize the bioactivity being exerted on Sclerotium rolfsii Sacc. in vitro by seed aqueous extracts from 64 yam bean (Pachyrhizus spp.) genotypes as well as their maceration times (0, 48 and 72 h). Three experiments were carried out following a completely randomized design with 64 treatments (potato-dextrose-agar PDA+extracts) with two controls (PDA with no extract and PDA+Cabrio® Top...

Author(s): Rodrigo Gonçalves de Lima, César Augusto Ticona-Benavente, Danilo Fernandes da Silva Filho, Leandro Sousa e Silva , Rândrea Grazziella Verçosa Guimarães  and Rogerio Eiji Hanada

In-vivo anti-inflammatory activity of different parts of Adansonia Digitata

June 2021

The aim of the study is to investigate the anti-inflammatory property of the different parts of Adansonia digitata (Malvaceae) extracts. A. digitata is an important medicinal plant to West Africa including Ghana. The plant is used effectively in folk medicine to treat inflammatory diseases such as joint disorders, asthma, toothache and painful swelling. Carrageenan-induced pedal oedema in 7-day old chicks was was the...

Author(s): Anna Kwarley Quartey, Isaac Ayensu, Emmanuel Orman, Nana Ama Mireku-Gyimah, Yakubu Jibira and Phoebe Esinam Goku  

Evaluation of leaf extracts of Artemisia afra Jacq. ex Willd. and Leucosidea sericea Eckl. & Zeyh. for genotoxicity and the modulation of EMS-induced genotoxicity

June 2021

A battery of short-term in vitro assays for apoptosis and/or cell cycle arrest, cytotoxicity, genotoxicity and antigenotoxicity are used to screen and establish the efficacy of medicinal plants. This study evaluated three concentrations (0.1, 0.2 or 0.4 mg/ml) of methanolic leaf extracts of Artemisia afra and Leucosidea sericea and their individual mixtures with Ethyl methanesulfonate (EMS) (0.15 mg/ml) for induction of...

Author(s): Asita Okorie A., Sibusisiwe Magama and Lengala Nthabiseng M.  

Anti-bacterial activity of secondary metabolites from Chrysanthemum cinerariaefolium

June 2021

This study evaluated antibacterial activity of Chrysanthemum cinerariaefolium (pyrethrum) flower dichloromethane crude extract, fractions and isolated compounds; pyrethrin II, jasmolin I and cinerolone against methicillin-resistant Staphylococcus aureus (MRSA), Pseudomonas aeruginosa, Staphylococcus aureus and Shigella sonnei. The isolated compounds were obtained by carrying out column chromatography on dichloromethane...

Author(s): Caroline J. Kosgei, Festus Tolo, Josphat C. Matasyoh, Meshack Obonyo, Peter Mwitari, Lucia Keter, Richard Korir and Beatrice Irungu  

Indigenous knowledge of plant uses by the community of Batiaghata, Khulna, Bangladesh

June 2021

Southwestern region of Bangladesh is very rich in floral diversity, and their diversified uses. An extensive survey was conducted to investigate ethnobotanical applications of botanical species by the community of Khulna, Bangladesh. We focused on plants and community relationships, identify the most important species used, determine the relative importance of the species surveyed and calculated the Fidelity level (FI)...

Author(s): Tama Ray, Sharif Hasan Limon, Sajjad Hossain Tuhin and Arifa Sharmin  

Phytochemical properties and antimicrobial activity of Buchholzia coriacea and Psychotria microphylla leaf extracts on bacterial pathogens isolated from aquatic environments in Nigeria

June 2021

The use of medicinal plants as alternative therapy for the treatment of microbial infections is significant in the maintenance of good health, especially in developing countries. The aim of this study was to determine the phytochemical composition and antimicrobial activity of Buchholzia coriacea and Psychotria microphylla leaf extracts on bacteria isolated from aquatic environments in Nigeria. Exactly 736 water samples...

Author(s): Ude I. U., Moses I. B., Okoronkwo C., Ovia K., Okafor C., Chukwunwejim C. R., Okata-Nwali O. D., Iroha C. S., Akuma S., Peter I. U., Uzoeto H. O., Ngwu J. N., Onuorah A. L., John-Onwe B. N. and Iroha I. R.  

In vivo study of antiplasmodium and histological activity of Garcinia kola and Aloe vera extracts against falciparum malaria

May 2021

This study focuses on testing the efficacy of herbal remedy used in many homes within the South-Eastern part of Nigeria to treat malaria and also the histopathological effect of the remedy on albino rats. Twenty rats were procured and distributed with five rats to one group. Group 1 received Garcinia kola and Aloe vera extracts, Group 2 received only G. kola extract, Group 3 is negative control and Group 4 is positive...

Author(s): Onyinyechi Cecilia Amobi-Alor, Adanna Cynthia Eze, Chineye Lucy Ugwute, Nneka Mariam Unachukwu, Chika Udeh, Simeon Okolo, Chidimma Claribel Chikezie, Kelechi Mbah-Omeje and Felix Chukwuebuka Onyia  

New naphthalene derivative isolated from Diaporthe sp. host to Syzygium cordatum Hochst.ex Krauss plant

May 2021

Fungal endophytes are regarded as inexhaustible sources of pharmaceuticals and agrochemicals with profound antibacterial, anticancer or antifungal activities. Diaporthe sp., an endophytic fungus residing in medicinal plant S. cordatum, showed a good antagonism against bacterial pathogens of beans; Pseudomonas syringae pv phaseolicola (Psp) and Xanthomonas axonopodis pv phaseoli (Xap), with zones of inhibitions of 14.00...

Author(s): Towett Kipngetich Erick, Joyce Jepkorir Kiplimo and Josphat Matasyoh  

Berberis vulgaris aqueous extract prevention of carbon tetrachloride induced hepatotoxicity and lipopolysaccharides/paracetamol induced hepatitis in rats

May 2021

The aim of this study was to evaluate the effect of Berberis vulgaris water extract (BWE) against CCl4-induced hepatotoxicity and LPS/PCM induced- hepatic inflammation in the experimental animal models. CCl4 (100 ug/kg, oral) administration for 28 days as well as the co-administration of LPS (250 ug/kg bw) and PCM (2 g/kg bw) for 28 days resulted in massive elevation in serum and hepatic prooxidants and inflammatory...

Author(s): Mohamed Ahmed Moustafa, Doaa Ahmed Ghareeb, Maha A. El-Demellawy, and Mohamed Mahmoud Elsayed  

Bioactive profile of mandacaru fruits and cytotoxicity against the L929 cell line

May 2021

Mandacaru (Cereus jamacaru DC. Subsp. Jamacaru) is native to the Brazilian Caatinga and is part of the Cactaceae family. Mandacaru fruits are attractive in taste and flavour, although they are not widely commercialised. However, there is limited scientific literature on the composition of this fruit. Therefore, the present work was aimed at analysing the physicochemical composition, as well as in vitro antioxidant...

Author(s): Jamiles Francisca dos Santos, Jenisson Linike Costa Gonçalves, Raphael Amancio de Jesus, Paulo Cesar de Lima Nogueira, Ricardo Scher, Antonio Martins de Oliveira Júnior and Jane de Jesus da Silveira Moreira,  

Polyphenols quantification and antioxidant activity of methanolic and aqueous extracts from eight medicinal plants used to manage avian diseases in Burkina Faso

May 2021

The present study aimed to quantify the polyphenols and evaluate the antioxidant activity of methanolic and aqueous extracts from eight medicinal plants used by the poultry farmers to manage avian diseases in Burkina Faso. Total phenolics and total flavonoids were quantified using Folin-Ciocalteu and AlCl3 reagents, respectively. The antioxidant activity was evaluated using three methods:...

Author(s): Windmi Kagambega, Roland Nâg-Tiéro Meda,Benjamin Kouliga Koama ,, Anne-Flora Drabo, Hadidjatou Belem, Der Dabire, Jacques Kabore, Amadou Traore and  George Anicet Ouédraogo  

Farmers’ awareness and ethno-veterinary practices regarding porcine cysticercosis in the province of Boulkiemde, Burkina Faso

April 2021

Porcine cysticercosis is a major public health issue in Burkina Faso. This study investigated farmers’ awareness and ethno-veterinary practices regarding this disease in Boulkiemde province, Burkina Faso. A survey was done with 132 randomly selected pig farmers in 10 villages of two municipalities of Boulkiemde province, using a semi-structured questionnaire. The majority of interviewed farmers (54%) were from the...

Author(s): Laibané Dieudonné Dahourou, Almamy Konaté, Arnaud Stéphane Rayangnéwendé Tapsoba, Bénéwendé Aristide Kaboré, Adama Kabore, Hamidou Hamadou Tamboura and Amadou Traoré  

Antibacterial effects of the organic crude extracts of freshwater algae of Sulaymaniyah, Kurdistan Region, Iraq

April 2021

In the recent past, the importance of freshwater algae has grown enormously due to their antibiotic activity against certain species of bacteria known for several disease states like endocarditis, external otitis, skin rash, etc. Also, there is a growing concern among the immunocompromised individuals that they may be susceptible to antibiotics and anti-fungal resistant infections resulting in increased fatality rates....

Author(s): Noel Vinay Thomas, Dlzar Dlshad Ghafour, A Salomy Monica Diyya, Rawa Raouf Ismail, and Lanya Karwan Jalal     

Seasonal impacts on antifungal activity and chemical composition of extracts from medicinal plants Turraea holstii and Clausena anisata

April 2021

Curative dependence on season of harvest for medicinal plants is an alleged claim by traditional health practitioners. This study aimed to verify these claims by investigating antifungal activity and chemical profiles of two traditionally used medicinal plant species: Turraea holstii and Clausena anisata harvested in the rainy and dry seasons, with a view of establishing appropriate the season for optimal activity. The...

Author(s): Francis Machumi, Ester Innocent and Pius Yanda  

Anti-hyperglycemic effects of Stemonocoleus micranthus (Fabaceae) stem bark on alloxan-induced hyperglycemic rats

April 2021

This study evaluated the anti-hyperglycemic potential of Stemonocoleus micranthus Harms. (Fabaceae) stem bark. Three models used in this study were: normoglycemic animal model, oral glucose tolerance test (OGTT) and alloxan-induced hyperglycemic model for acute and prolonged administration. Five (5) groups of rats (n=5) were used for all models; group 1 served as the control (received 2 ml/kg of distilled water; p.o.),...

Author(s): Florence N. Mbaoji, Collins A. Onyeto, Okechukwu O. Ndu, Bonaventure C. Obi and Akachukwu M. Onwuka  

Antioxidant effect of Hymenaea courbaril L (Jatobá) sap on the healing of wounds on mice

April 2021

The use of natural products with curative action is a common cultural practice in the Brazilian Amazon, but little explored scientifically. The effect of Hymenaea courbaril L sap extract and its contribution to wound healing in mice was evaluated. The antioxidant potential of the extract was studied using the radical 1,1-diphenyl-2-picrilhidrazil and 2,2'-azino-bis (3-ethyl benzothiazoline-6-sulfonic) acid radical,...

Author(s): Ruth Silva Lima da Costa, David Smangoszevski Martins, Laan Diego Carvalho Peixoto, Bárbara Janaína Paula da Silva, Larissa Barbosa Borges, Emerson Silva Lima,  Hector Henrique Ferreira Koolen, Dionatas Ulises de Oliveira Meneguetti,  Ana Flávia Marçal Pessoa and Romeu Paulo Martins Silva  

Antiurolithiatic activity of selected plants extracts against calcium oxalate crystals

April 2021

The present study was designed to evaluate the antiurolithiatic activity of selected plants extracts (Achyranthes aspera, Lawsonia inermis, Ficus benghalensis, Raphnus sativus and Macrotyloma uniflorum). The methanol extract of selected plants was analysed for in-vitro antiurolithiatic activity using nucleation, aggregation and growth assay of calcium oxalate (CaOX) monohydrate crystals. The nucleation, aggregation and...

Author(s): Sushant Aryal, Puspa Kuwar and Chhitij Thapa  

Chambá (Justicia pectoralis) syrup for the treatment of cough and respiratory symptoms: A randomized clinical trial

March 2021

Cough is a common pediatric complaint, resulting in frequent doctor’s office or hospital visits. In Brazil, the leaves of chambá (Justicia pectoralis) have been used extensively in herbal preparations for the treatment of many respiratory problems such as cough, bronchitis, and asthma. Thus, this study aimed to assess the effectiveness of chambá syrup for the treatment of cough and respiratory...

Author(s): Wilcare de Medeiros Cordeiro Nascimento, Francisco Plácido Nogueira Arcanjo, Mary Anne Medeiros Bandeira, Bruna Linhares Prado, Maria Ester Frota Fernandes, Elayne Cristina Oliveira Brito, Bianca Frota Monte, Aristides Avilo do Nascimento, Antonio Flávio Queiroz de Oliveira, Leandro Cordeiro Portela and Cecília Costa Arcanjo  

Chemical and organic fertilizer: The effect on apiin production by Petroselinum crispum var. neapolitanum Danert

March 2021

Parsley (Petroselinum crispum var. neapolitanum Danert) is a vegetable species with potential for pharmaceutical use because it contains apiin, a flavonoid that stands out for having biological activities, such as antioxidant. The aim of this study is to evaluate the influence of chemical or organic fertilizers on the nitrogen metabolism and production of flavonoids in parsley at different stages of development, aiming...

Author(s): Mylena Firmiano de Andrade, Luiziene Soares Alves, Bruna Cristina Borges Machado, Marco Andre Alves de Souza, Rosane Nora Castro, Douglas Siqueira de Almeida Chaves and André Marques dos Santos  

Toxicological evaluation of Zanthoxylum zanthoxyloides (Lam) Zepernick & Timler root bark used as biopesticide and medicine

February 2021

Toxicological studies were carried out to investigate the effect of consumption of Zanthoxylum zanthoxyloides root bark widely used in traditional medical practices and as protectant of stored cereal products in Nigeria, using albino rats. Serum, kidney and liver were tested for oxidation stress and tissue damage markers; aspartate amino transferase (AST), alanine amino transferase (ALT), urea, bilirubin and creatinine...

Author(s): Mohammed Gbate, Olufemi Michael Ashamo and Akinwande Lawrence Kayode  

Plants for veterinary use in the Montaña Palentina region (Palencia, Spain)

February 2021

Profound social changes that have occurred in recent decades in rural society have led to the abandonment of ethno veterinary practices and knowledge, traditionally used to treat and prevent animal diseases. The main objective of this ethno botanical work is to document the traditional veterinary uses of plants in the Montaña Palentina region (Palencia, Spain). The data obtained has been compiled through 139...

Author(s): Juan Cruz Pascual and Baudilio Herrero  

Aphrodisiac activity of ethanol extract and fractions of Fadogia cienkowskii Shweinf. Rubiaceae roots in albino rats

February 2021

Fadogia cienkowskii is a shrub whose roots are used in many communities of Northern Nigeria to improve sexual performance; however, there is no scientific study to verify this claim. This study determined the effect of 70% ethanol extract of F. cienkowskii roots and its fractions (ethyl acetate, n-butanol, and residual ethanol) on mating behaviour (mounting, intromission and ejaculation) and serum testosterone...

Author(s): Jurbe Gofwan Gotep, Sunday Yakubu Sabo, Sunday Makama, Mary Ogonnaya Uguru and Francis Kanayo Okwuasaba  

Occurrence of calcium oxalate crystals in some wild plants used in traditional medicine in Saudi Arabia

February 2021

Plants are widely used in traditional medicine, but could be detrimental to patients, due to the presence of some harmful substances such as calcium oxalate (CaOx) C2CaO4 crystals. The presence, morphology and distribution of CaOx crystals were investigated in 60 wild, herbal plant species from the Al Qussim Region, Saudi Arabia. This was done via light microscopy of transverse sections of stems and leaves using light...

Author(s): Mohamed El-Zaidy and Abdulaziz A. Alsahli  

Qualitative and quantitative phytochemical profiling of crude fractions of Pechuel-Loeschea leubnitziae leaves

February 2021

Pechuel-Loeschea leubnitziae is a predominant medicinal plant in Namibia. It is traditionally utilized in treatment of gastrointestinal issues, sexually transmitted infections and common cold. Despite its therapeutic potential, the phytochemicals profile and compounds compositions are yet to be scientifically validated. This study was conducted to determine the spectrum and total phytochemical constituents present in P....

Author(s): Mariah Ndilimeke Muhongo, Mourine Kangogo and Christine Bii  

Ethnobotanical study of selected medicinal plants used for the treatment of respiratory diseases in Southern Brazil

January 2021

This survey explored the ethnobotanical uses of selected medicinal plants; Adiantum raddianum C. Presl. (Pteridaceae), Lippia alba (Mill.) N. E. Brown (Verbenaceae) and Coronopus didymus (L.) Sm. (Brassicaceae) used for respiratory diseases in Southern Santa Catarina (Brazil). This is timely as the incidence of respiratory disease is increasing in this state. Information was obtained through both interviews using a...

Author(s): Marília Schutz Borges, Michele Darós Freitas, Paula da Silva Cardoso, Vanilde Citadini- Zanette, Silvia Dal Bó and Patrícia de Aguiar Amaral  

Development and validation of a new method to quantify vitexin-2''-O-rhamnoside on Passiflora L. extracts

January 2021

The genus Passiflora L. is the most representative of the Passifloraceae family and includes about 500 species. The aim of this work was to analyze three different passion fruit species in relation to vitexin-2´´-O-rhamnoside content by high-performance liquid chromatography coupled to a diode-array ultaviolet detector. Samples were prepared by water infusion (10% w/v), dried by lyophilization, and stored in...

Author(s): Lorenna C. da Rosa, Monica R. P. Siqueira, Francisco J. R. Paumgartten, Georgia Pacheco, Elisabeth A. Mansur de Oliveira and Davyson de L. Moreira,  

Chemical composition and antibacterial activity against Escherichia coli of extracts of a common household plant

January 2021

Plants have long been a source for a wide variety of compounds with medicinal properties; of significant interest are plant antimicrobial compounds. Given the continual increase in bacterial resistance, it is imperative that new antimicrobial compounds need to be discovered. The purpose of this study was to screen some common household plants for antibacterial activity, specifically against Escherichia coli. Leaves of...

Author(s): Maria K. Kozar, Joanna G. Kondylis, Katerina A. Drouvalakis and Leland G. Kozar  

Ethnomedical survey of plants used for the management of HIV and AIDS-related conditions in Mbulu District, Tanzania

January 2021

The aim of this Study was to document medicinal plants used in the management of HIV and AIDS-related conditions in Mbulu District. An ethnomedical survey was conducted using a semi-structured questionnaire. The main HIV and AIDS-related conditions considered during this study were; cough, frequent fevers, diarrhea, weight loss, oral thrush, genital warts, candidiasis, abscesses, skin rashes, shingles and venereal...

Author(s): Alphonce Ignace Marealle, Mainen Moshi, Ester Innocent, Michael Qwarse and Kerstin Andrae-Marobela  

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