Journal of
Medicinal Plants Research

  • Abbreviation: J. Med. Plants Res.
  • Language: English
  • ISSN: 1996-0875
  • DOI: 10.5897/JMPR
  • Start Year: 2007
  • Published Articles: 3785

JMPR Articles

Tracking antibacterial components of Pteris multifida Poir and its antibacterial mechanism

June 2022

Pteris multifida is an effective Chinese herb for treating dysentery caused by Escherichia coli. It might be a good veterinary antibiotic alternative. In this study, we optimized the extraction condition based on the antibacterial activity of crude extracts from P. multifida, tracked its antibacterial components, and investigated their antibacterial activity, as well as its antibacterial mechanism. The results revealed...

Author(s): Zhong Wang#, LiQi Wang#, JingJing Qian, PingYao Nan and XiaoYing Wang  

In vivo antimalarial activity, safety and phytochemical screening of Canthium multiflorum (Schumach. &Thonn.) Hiern (Rubiaceae)

June 2022

Canthium multiflorum (Thonn.) Hiern (Rubiaceae) is a popular herb used by traditional healers in western Burkina Faso. C. multiflorum leaves are widely used in decoction to treat malaria. The present study aims to evaluate its in vivo potential against malaria parasites in mice. The antimalarial activity of the organic and aqueous extracts of C. multiflorum leaves was evaluated on Plasmodium berghei Anka in NMRI mice...

Author(s): KOAMA Benjamin Kouliga, YERBANGA Rakiswendé Serge, DA Ollo, YOUGBARE Sibidou, NATAMA Hamtandi Magloire, OUEDRAOGO Georges Anicet, OUEDRAOGO Jean Bosco, and TRAORE/COULIBALY Maminata  

Phytochemical composition and in vitro antileishmanial activity of Bidens pilosa, Tithonia diversifolia and Sonchus oleraceus extracts

June 2022

Leishmaniasis is the second-largest parasitic killer in the world (after malaria). Currently, there are no effective vaccines or therapeutic interventions thus creating a gap for new alternative remedies in the management of the disease. Medicinal plants offer this attractive option as antileishmanial agents since they are relatively safe, locally available and affordable. The study assessed antileishmanial activity of...

Author(s): Thomas O. Momanyi, Josphat C. Matasyoh, Stephen M. Karori and Johnstone M. Ingonga  

Medicinal plants of the African traditional pharmacopoeia in the management of bovine trypanosomosis: A review

June 2022

Traditional medicine has remained the most affordable and readily available source of treatment for primary care in poor African communities. Despite the increasingly common practices of traditional medicine to treat animal diseases, this rich endogenous knowledge is not sufficiently documented. The objective of this review is to synthesize information on ethnoveterinary practices to treat bovine trypanosomiasis in...

Author(s): C. Iwaka,, E. V. B. Azando, F. C. C. Hountondji, H. S.S. Worogo, E. Y. Attakpa, P. A. Olounlade, and M. S. Hounzangbe-Adote

Ethnobotanical and ethno-pharmacological approach to ichthyotoxic plants of Gabon

May 2022

This ethnobotanical and ethno-pharmacological study was conducted to know the plants used in fishing practices and to show their importance in traditional medicine in Gabon. For this study, 100 questionnaires were administered to individuals in the fishing and traditional medical domains. 701 plants belonging to 16 different floristic families, including Fabaceae (41%), Rubiaceae (13%), and Rutaceae (15%) were commonly...

Author(s): Ulrich Gauthier Mayombo Mouele, Christiane Atteke Nkoulembene, Bertrand Kokolo, Silas Lendzele Sevidzem and Ibrahim  

Anti-quorum sensing potential of Ageratum conyzoides L. (Asteraceae) extracts from Burkina Faso

May 2022

Pseudomonas aeruginosa causes infections in humans, particularly immune-compromised patients with cystic fibrosis, severe burns, and HIV, resulting in high morbidity and mortality. The pathogenic bacteria, P. aeruginosa, produces virulence factors regulated by the mechanism called quorum sensing system. The aim of this study was to assess the anti-quorum sensing activity of Ageratum conyzoides extracts. Chloroform...

Author(s): Eli Compaoré, Vincent Ouédraogo, Moussa Compaoré, Ablassé Rouamba, and Martin Kiendrebeogo

Medicinal plants in oral health and the intergenerational transfer of knowledge: Resilience to cocoa culture in southern Bahia

May 2022

Ethnobotanical surveys have proved plant usage in the treatment of oral diseases; however, in areas where cocoa farming influenced socioeconomic reality there is a lack of information about preservation of traditional knowledge related to oral conditions treatment. Family Health Strategy (FHS) users and community experts were interviewed with socioeconomic characteristics and ethnobotanical information being obtained...

Author(s): Bolívar de Oliveira Landi, Carlos Eduardo Dias Igídio, Brenda di Pace Lucena, Marcelo Inácio Ferreira Ferraz, Gabriel Bastos Teixeira and Aline Oliveira da Conceição  

Phytochemical analysis and safety evaluation of ethanol roots extract of Erythrina sacleuxii hua in Wistar albino rats

April 2022

Erythrina sacleuxii, one of five Erythrina species found in Kenya, is a stiffly multi-branched deciduous tree reported to have antiplasmodial, antifungal, anti-bacterial and anti-cancer activities. This study aimed at evaluating acute and sub-acute oral toxicity of E. sacleuxii roots ethanolic extract. Phytochemical analysis was conducted on Fourier transform infrared spectroscopy and Gas Chromatography-Mass...

Author(s): Mwanasiti O. Mwakumanya, Florence A. Ng’ong’a, Mutinda C. Kyama and Esther N. Maina  

Antioxidant and antihyperlipidemic activities of unique nicotinyl polysaccharide from the green seaweed Ulva pertusa

April 2022

Nicotinyl derivative of polysaccharide (NU) from the green seaweed Ulva pertusa (Chlorophyta) has unique structure and strong antioxidant activity in vitro. In the present study, in vivo antioxidant and antihyperlipidemic activities were tested in the livers of hyperlipidemic mice. Activity levels of superoxide dismutase, glutathione peroxidase (GSH-PX), catalase, and malondialdehyde were observed. At the 500 mg/kg...

Author(s): Yuzhou Wan, Xintao Chang, Lin Liu, Shaopeng Wang, Huimin Qi and Fang Yan  

In vitro antiproliferative potential of crude extracts from Carica papaya L. (Caricaceae) black seeds against prostate cancer cell lines'

April 2022

Black seeds from papaya plants are utilized as traditional medicine in African and Asian cultures to improve the functioning of the male reproductive system and management of prostate cancer. This study analyzed the phytochemical composition, antiproliferative activity and cytotoxicity of Carica papaya black seeds against the prostate cancer cells and Vero cells. Phytochemical screening was performed by standard...

Author(s): Benson Mcheza Kateihwa, Hulda Swai, Jeremiah Waweru Gathirwa and Elingarami Sauli  

Herbal medicine development and compliance to regulatory guidelines in Imo State Nigeria

April 2022

Herbal medicine is an important age-long resource for healthcare. The aim of this study was to determine the development of herbal medicine in relation to compliance to regulatory guidelines and product development in pursuance of the integration of herbal medicine into the healthcare system in Nigeria. Using Imo State as a case study, a cross-sectional investigation was conducted among the Traditional Medicine...

Author(s): Adigwe P. Obi, Builders F. Philip, Ibekwe, N. Nneka and Onavbavba Godspower  

Analgesic, anti-inflammatory and oxytocic activities of Dracaena steudneri Engl. stem bark aqueous extract in Wistar rats

April 2022

Dracaena steudneri Engl. (Dracaenaceae) is a medicinal plant that is used in labour by traditional birth attendants to induce labour, relieve pain and treat various diseases; albeit no documentation. This study determined the analgesic, anti-inflammatory and oxytocic effects of the D. steudneri stem bark aqueous extract. D. steudneri stem bark was collected, authenticated, oven-dried at 45ºC for 48 h, pulverized...

Author(s): Mercy Gladys Tenywa, Amon Ganafa Agaba, Clement Olusoji Ajayi, Casim Umba Tolo and Esther Katuura  

Brown macroalgae: Promising sources of bioactive products against human herpesviruses

March 2022

Marine brown macroalgae have stood out as important sources of new bioactive products, such as antimicrobial, anticoagulant, anti-inflammatory and antiviral drugs. This study aimed to review the literature on the applications of products derived from brown macroalgae as antiviral agents against human herpesviruses. To date, species of seven distinct orders of brown algae have been studied for this purpose, such as...

Author(s): Maria Leonisa Sanchez Nuñez, Vitor Won-Held Rabelo, Izabel Christina Nunes de Palmer Paixão and Valéria Laneuville Teixeira,  

Antibiotic potential of a crude ethanol extract from Asplenium serratum L. fern leaves

March 2022

Asplenium serratum L. (Aspleniaceae) is a terrestrial, epiphytic or humicole fern used as traditional medicine in different countries to treat infection. As such, this study aimed to assess the antibacterial potential of a crude ethanol extract from A. serratum leaves against multidrug-resistant bacteria from a hospital setting. Fern leaves were dried and ground using 96° Gay Lussac ethanol, with the extract...

Author(s): Marcelo Guerra Santos, Sâmella Schuindt Leal, Fábio Aguiar-Alves and Leandro Rocha  

Acute toxicity, analgesic, and smooth muscle relaxant effects of the aqueous root extract of Asparagus racemosus from Kenya

March 2022

The plant Asparagus racemosus is used traditionally in Kenya for a variety of medicinal purposes including in the management of pain, asthma, and premature labour. However, a dearth of empirical studies means that there is limited information on the acute toxicity and pharmacological effects to support these uses by the local variety of the plant. The aim of this study was, therefore, to evaluate the acute toxicity,...

Author(s): Godfrey Mayoka, Peggoty Mutai, Faith Okalebo and Daniel Juma  

Antiplasmodial activity and phenolic composition of Brazilian Salix humboldtiana Willd. extract and fractions

February 2022

Salix humboldtiana Willd. (Salicaceae) colonizes Brazilian riverine forests and, besides other congeneric species, is traditionally used to treat fever. In folk medicine, it is even used as a Quinine substitute to treat malaria fever. Although its occurrence worldwide was largely reduced between 2000-2015, in Brazil, the case numbers induced by Plasmodium falciparum have increased. Thus, new tools and strategies are...

Author(s): Ianna Dias Ribeiro Silva, Uêbem Fernandes Ramos, Luciana Esquerdo Cerqueira, Andressa Santa Brígida da Silva, Geraldo Alves Damasceno Junior, Carlos Alexandre Carollo, Ivanildes dos Santos Bastos, Patrícia Puccinelli Orlandi, Heike Markus-Michalczyk and Wagner Luiz Ramos Barbosa  

Evaluation of the anxiolytic effects of acute administration of Passiflora alata extract in wistar rats submitted to swimming

February 2022

Anxiety is present in several psychiatric disorders, and pharmacological treatment has limitations. Therefore, there is a search for new therapeutic approaches. This study aimed to evaluate the anxiolytic effect of acute administration of the dry extract of Passiflora alata (P. alata) leaves in male Wistar rats submitted to swimming. The animals were randomly divided into four groups (n = 8) (G1 to G4). G2 to G4 were...

Author(s): Airton José Mendes, Annik Ianara de Souza Greco, Renan Santiago Pereira, Wilson Roberto Malfará, Maricelma da Silva Soares de Souza, Sandra Maria Barbalho,, Elen Landgraf Guiguer, and Adriano Cressoni Araujo,  

Flavonoid content and antioxidant potential of leaf extracts of Passiflora setacea cv BRS Pérola do Cerrado, a new wild passion fruit cultivar

February 2022

Passiflora setacea D.C. is a wild species native to the Brazilian Cerrado, with agronomic and medicinal potentials. The cultivar BRS Pérola do Cerrado is the first registered and protected cultivar of a wild Passiflora and has become an alternative to the passion fruit market due to its desirable characteristics for food, ornamental and pharmaceutic industries. Since plant tissue culture techniques are considered...

Author(s): Raphaela Santos-Tierno, Renata Garcia, Eduardo Fonseca, Fábio Faleiro, Davyson Moreira, Georgia Pacheco and Elisabeth Mansur  

Antibacterial, antiquorum sensing, antibiofilm activities and chemical profiling of selected South African medicinal plants against multi-drug resistant bacteria

February 2022

South African indigenous plants have been predominantly studied for their antibacterial abilities, overlooking their antipathogenic and antivirulence (also known as antiquorum sensing) potential. Hence, this study explored the selected medicinal plants as possible agents capable of interfering with bacterial growth, quorum sensing and biofilm formation and identified their respective bioactive compounds. Ten medicinal...

Author(s): Itumeleng Tsebang Baloyi, Idowu Jesulayomi Adeosun, Abdullahi Ahmed Yusuf and Sekelwa Cosa  

Antioxidant and DNA damage protective activities of selected endophytic actinobacteria isolated from Harpagophytum procumbens: A Kalahari desert-adapted plant

February 2022

Given that synthetic antioxidants are currently in use and have been demonstrated to have known negative side effects, it is important to look for natural antioxidant sources. Endophytic actinobacteria, especially those associated with medicinal plants, are one understudied source. The goal of this study was to investigate whether the secondary metabolites of endophytic actinobacteria isolated from Harpagophytum...

Author(s): Magdalena Elizabeth Lang, Timothy Sibanda, Stefan Louw and Jean Damascène Uzabakiriho  

Noni essential oil associated with adjuvants in the production of phytoalexins and in the control of soybean anthracnosis

January 2022

Amongst the most important agricultural products in Brazil, the soybean stands out, mainly as an export good. One of the end-of-cycle diseases, Anthracnose, caused by the fungus Colletotrichum truncatum (Schwein.) leads to severe damage to grain quality and yield. The use of natural products as a substitute for conventional pesticides for plant diseases control is an alternative found to reduce food contamination and...

Author(s): Natália Pinto e Nosé, Mateus Sunti Dalcin, Bruna Letícia Dias, Rodrigo Solci Toloy, Dalmarcia Souza Carlos Mourão, Marcos Giongo, Alex Cangussu, Sabrina Helena da Cruz Araújo and Gil Rodrigues dos Santos  

Ethnobotanical survey of medicinal plants utilized by forest edge communities in southern Sierra Leone

January 2022

A total of 128 medicinal plant species belonging to 71 genera and 46 families were identified and used to treat 42 human ailments. Euphorbiaceae was the leading family with 14 species, followed by Rubiaceae and Leg-Caesalpiniaceae with 12 and 8 species, respectively. Seven species (Coffea stenophylla, Garcinia afzelii, Mitragyna stipulosa, Irvingia gabonensis, Milicia regia, Nauclea diderrichii and Nesogordonia...

Author(s): Jonathan Johnny, Aiah Lebbie and Richard Wadsworth  

Bioactive small-molecule constituents of Lao plants

December 2021

Laos has a rich plant diversity, and medicinal plants are used extensively in Lao traditional medicine for the treatment of a variety of human diseases. However, only a relatively small number of these plants have been investigated for their major components with potential antitumor, anti-infective, and other types of bioactivities. These species include Asparagus cochinchinensis, Diospyros quaesita, Gongronema...

Author(s): Yulin Ren, Bethany G. Elkington, Joshua M. Henkin, Kongmany Sydara, A. Douglas Kinghorn and Djaja D. Soejarto,  

Optimized flow cytometric protocol and genome size estimation of Sabah snake grass (Clinacanthus nutans)

December 2021

Clinacanthus nutans is an economically important medicinal plant that can be found grown in many countries in the Asian region. Useful medicine properties such as anti-cancer, anti-bacteria, and anti-viral, backed by its high content of phytochemical compounds such vitexin, isovitexin, stigmasterol and lupeol has increased the demand for C. nutans in the market. Extensive work had been carried out on its content and...

Author(s): Vidhyaini Kandaiah, Nallammai Singaram and Kodi Isparan Kandasamy  

Effects of hydromethanol hypocotyls extract of Borassus aethiopum on sperm and gonadal indices of male Wistar rats

November 2021

Infertility resulting from sperm dysfunction is a serious health problem leading to psychological, economic, and medical implications worldwide. Borassus aethiopum is a plant that has been used as an aphrodisiac. This study evaluated the effect of hydromethanol hypocotyls extracts of B. aethiopum on the sperm and gonadal indices of male Wistar rats. The extract was prepared and administered orally at doses of (250, 500...

Author(s): Mansur A. Ramalan, Adamu B. Shuaibu and Abdullahi H. Yaro  

Preliminary screening of the antimicrobial activity of nine medicinal plant species from Burkina Faso

November 2021

Infectious diseases, including skin infections, have always been treated by plants and other natural products since ancient times. This study investigated the antimicrobial activity of nine medicinal plant species from Gonsé Forest and Bangreweogo Park, Burkina Faso on seven microbial strains involved in skin infections. Sixty-eight organic and aqueous extracts from leaves, stem and root barks of the nine plants...

Author(s): Ollo Youl, Sibidou Yougbaré, Palpouguini Lompo, Boubacar Yaro, Christian Marc Tahita, Halidou Tinto, Adama Hilou and Maminata Traoré/Coulibaly  

Comparing checkerboard, isobologram and CCD methods for drug combination: A case study of ciprofloxacin and plant extracts on Escherichia coli and Shigella

October 2021

To investigate the interactive antimicrobial activity of conventional antibiotics, namely ciprofloxacin and Mangifera indica bark ethanol extract, Psidium guajava leaves essential oil against two Gram-negative bacteria using checkerboard, isobologram, and central composite design (CCD) methods. The checkerboard method was used for the determination of the fractional inhibitory concentration index (FICI) value needed for...

Author(s): Gislaine Aurelie KEMEGNE, Sylvain Leroy SADO KAMDEM, Maximilienne Ascension NYEGUE, Chantal MENUT and François-Xavier ETOA  

Protective effect of commercial extracts of oregano (Lippia graveolens) against cardiac ischemia-reperfusion damage

October 2021

Cardiac ischemia includes severe damage to heart muscle tissue due to decreased or cessation of blood flow, which involves failure to supply nutrients and oxygenation to heart cells. Causes can include blockages due to fat and cholesterol deposits. These damages include cell apoptosis, calcium and sodium concentration imbalance, loss of contraction force, and formation of reactive oxygen species. In the present work,...

Author(s): Gabriela Pérez Flores, Jose David Torres Tirado, Ramiro Martínez Acosta, Jorge Alejandro Chávez Aguirre, María Guadalupe Nieto Pescador, Maribel Cervantes Flores, Ashley Stephanie Herrera Godina and Eduardo Lozano Guzmán  

Ethnobotanical survey on medicinal plants traditionally used for treatment of intestinal parasitosis of animals and humans in Northern Benin

October 2021

Parasitic nematodes of the gastrointestinal (GI) tract remain a major threat to both human beings and livestock. The aim of this study was to document medicinal plants used in the management of intestinal parasitosis in the small ruminants and humans. Information relating to the different plants used in the treatment of human intestinal parasitosis and small ruminants was collected through an ethnobotanical survey...

Author(s): Lissette Houedenou DEGLA, Pascal Abiodoun OLOUNLADE,   Latifou LAGNIKA, Sabbas ATTINDEHOU, Abdou Madjid Olatoundé AMOUSSA, Christian Cocou DANSOU, Basile Saka Boni KONMY, Erick Virgile Bertrand AZANDO, and Sylvie Mawulé HOUNZANGBE-ADOTE  

SARS Cov-2 Structure, biology, immunology and clinical course: Exploring the value of traditional medicine in limiting COVID-19 individual risk and disease outcomes

October 2021

Since the onset of COVID-19 in early 2020, various approaches have been adopted worldwide by various state health authorities containing the ravaging pandemic. Tanzania adopted additional approach based on Tanzanian Traditional Medicines. This review aimed to explore the suitability of this local approach based on evaluation of the virus biology, pathogenesis and immunology in relation to the traditional medicines,...

Author(s): Erasto V. Mbugi, Joseph Otieno, Ted Mselle, Sauli E. John, Ruth Boniface, Florence Urio, Baraka S. Mkumbe, Samson Hilonga and Germana H. Leyna  

Comparative study of wild chamomile plants from the north-west of Morocco: Bioactive components and total antioxidant activity

October 2021

Morocco presents numerous plants due its localization between the Mediterranean Sea and Atlantic Ocean and the variability of its mountainous terrain, with a rich range of medicinal plants. Cladanthus mixtus (L.) Oberpr. & Vogt and Matricaria chamomilla L., two Asteraceae (Compositae) from Beni Hassane region in north-western Morocco are both used in traditional medicine for the treatment of different ailments. The...

Author(s): Amina EL MIHYAOUI, María Emilia Candela CASTILLO, Antonio CANO, Josefa HERNANDEZ-RUIZ, Ahmed LAMARTI and Marino Bañon ARNAO  

Studies of the anti-hyperglycemic and antioxidant activities of the extract of aerial yam (Dioscorea bulbifera)

October 2021

This study investigated the anti-hyperglycemic and antioxidant activities of methanol extract of Dioscorea bulbifera with a view to studying the possibility of utilizing the yam in the management of hyperglycemia. Methanol extracts of the peels (MEPL), fresh (MEFL), and the whole tuber (MEWT) were prepared, phytochemically screened and assayed for α-amylase. Hyperglycemia was induced in rats using intraperitoneal...

Author(s): Kelechi Nkechinyere Akinyele, Beatrice Oluyomi Emma-Okon, Adeniyi Oluwadare Fajobi, Adetoun Elizabeth Morakinyo and Oluboade Oluokun Oyedapo  

Phytochemical, elemental and functional group analyses of herbal material and extracts of Cassia sieberiana used in herbal drug formulation

October 2021

Cassia sieberiana is used traditionally for the treatment of several ailments. The lack of knowledge in the levels of essential mineral contents and heavy metal constituents of C. sieberiana normally collected from various sites for preparation of herbal products can pose serious health risks to consumers. The elemental contents (Ca, Mg, K, Na, Cl, Hg, Pb, As, Ni, Cd, Cu, Fe, Mn, Zn, N, S and C) of a mixture of the stem...

Author(s): Mary-Ann Archer, Micheal Odoi Kyene , Doris Kumadoh , Genevieve Naana Yeboah , Frederick Ayertey , Susana Oteng Mintah , Henry Brews-Daniels , Tonny Asafo Agyei , Alfred Ampomah Appiah and Peter Atta-Adjei Jnr  

Piper multinodum C.DC. (Piperaceae) essential oils chemical variation and biological activity against Mycobacterium tuberculosis

September 2021

Piper multinodum C.DC. belongs to the Piperaceae family, and is known as “Jaborandi-manso”. This species has no reported botanical, chemical, pharmacological and/or toxicological scientific studies, and has restricted occurrence in degraded Brazilian biomes. The Piper genus is known to be aromatic, the essential oils (EO) obtained from different organs have demonstrated significant biological activities, and...

Author(s): Ygor Jessé Ramos,, Claudete Costa-Oliveira, Irene Candido Fonseca, Diego da Silva Marcelino, Marlon Heggdorne-Araujo, Elena B. Lassounskaia, Michelle F. Muzitano, George A. Queiroz, Elsie F. Guimarães and Davyson de Lima Moreira,

Therapeutic applications of Caryocar brasiliense: Systematic review

September 2021

The interest and search for natural active principles with therapeutic properties from plants are growing, given their potential for use by the cosmetic and pharmaceutical industries. Thus, the objective of this review was to carry out a systematic analysis of scientific productions that have explored some therapeutic potential of Caryocar brasiliense. The methodology of the preferred reporting items was adopted for...

Author(s): Fábio Fernandes Bruno Filho, Wanessa Ferreira Ataíde, Mônica Rodrigues Ferreira Machado, Ariel Eurides Stella, Liliane Nebo, Sandra Aparecida Benite-Ribeiro, Frederico Augusto Guimarães Guilherme and Andréia Vitor Couto do Amaral

Chemical investigation, toxic potential and acetylcholinesterase inhibitory effect of Parkia platycephala leaf and seed extracts

September 2021

The present work evaluated the inhibitor potential of acetylcholinesterase, the preliminary toxicity and determination of active components of different leaf and seed extracts of Parkia platycephala. All extracts were obtained through hot extraction in a closed system (Soxhlet). To obtain the leaf and seed hexanic, methanolic, and ethanolic extracts (LHE, LME, LEE, and SHE, SME, and SEE), sequential extraction was...

Author(s): Rachel de Moura Nunes Fernandes, Maria Angelica Melo Rodrigues, Juliane Farinelli Panontin, Daniela Ribeiro Alves, Selene Maia Morais, Ilsamar Mendes Soares  and Elisandra Scapin..

Effect of n-hexane extract of baobab (Adansonia digitata) fruit on biochemical parameters of l-ng-nitro arginine methyl ester induced hypertension in rats

September 2021

L-NG-Nitro arginine methyl ester (L-NAME) was used to induce hypertension in this experiment and the intervention plant extract was Adansonia digitata fruit. A total of 30 rats were used for this research and divided into 6 groups of 5 animals each. Group 1 was control (water and feed ad libidum), group 2 (L-NAME), group 3 (ramipril 10 mg/kg), group 4 (A. digitata 200 mg/kg), group 5 (A. digitata 400 mg/kg) and group 6...

Author(s): Ediale Joshua Richard, Innocent Abi and Olasupo Stephen Adeniyi

Composition and antioxidant potential of leaf and stem essential oils from Nigerian Indigofera spicata Forssk

September 2021

The chemical compositions and antioxidant evaluation of the essential oils (EOs) obtained by hydrodistillation from the leaf and stem of Indigofera spicata Forssk (Fabaceae) grown in Nigeria have been studied. The EOs were analyzed using gas chromatography coupled with mass spectrometry (GC-MS) and the antioxidant potential was determined using 2,2-diphenyl-1-picrylhydrazyl (DPPH) free radical scavenging ability method....

Author(s): Temitope Adewumi Adeleye, Clement Odunayo Ajiboye, Emmanuel Onah Ojah, Toyin Patrick Okesanjo and Dorcas Olufunke Moronkola

Assessment of minimum growth conditions for in vitro conservation of Passiflora edulis Sims

August 2021

Passiflora edulis Sims, besides having economic and social importance, is included in the medicinal plant list that is considered of interest by the Unified Health System (Sistema Único de Saúde – SUS). Due to its high nutritional value, this species is widely used in food, cosmetics and pharmaceutical industries. It also contains carotenoids, as well as passiflorine and maracugine, which have...

Author(s): Manuella Silva Oliveira Souza, Eldo Ciano da Silva, Gabriella Silva Oliveira Souza Ciano, Claudia Cecilia Blaszkowski de Jacobi, Josemário Santana Bonsucesso, Weliton Antonio Bastos de Almeida and Mariane de Jesus da Silva de Carvalho

Chemical characterization and toxicological analyses of hydroalcoholic extracts from the stem and leaves of mangabeira (Hancornia speciosa Gomes) as a guide for the development of green cosmetics

August 2021

The increasing interest in green cosmetics has a major influence on the cosmetics market, whether due to the incorporation of the functionalities of the extracts, or the substitution of synthetic ingredients with natural ones. Yet, the natural substances found in those products must be evaluated for their chemical characterization and toxicity. This study determined the chemical profile and assessed the toxicity of stem...

Author(s): Juliane Farinelli Panontin, Rafaela Pereira Neres, Rachel de Moura Nunes Fernandes, Elisandra Scapin, and Carla Simone Seibert

Traditional Chinese medicine Zizhu ointment alleviates inflammatory activity during wound healing in diabetic rats

August 2021

Diabetic ulcers are a severe complication in patients with diabetes that often lead to amputation. The etiology of diabetes-induced wound healing impairment is multi-faceted. Persistent inflammation and deficient tissue regeneration have been suggested to impair wound healing in diabetes patients. Although new therapeutic approaches have been developed, many chronic wound treatments remain unsatisfactory, and more...

Author(s): Qiang Han, Liang Qin, Xiao Yang, Renyan Huang, Xiaoming Hu, Wenhui Li and Guobin Liu

Comparative studies of antioxidant and anti-inflammatory potentials of ethanolic leaf extract of Sorghum bicolor and Zea mays

August 2021

This study was designed to investigate the anti-inflammatory and anti-oxidant potentials of leaf extracts of Zea mays (maize) and Sorghum bicolor (sorghum) with a view of utilizing them as herbal tea on the management and treatment of oxidant and inflammatory disorders. The powdered plant materials: (Z. mays, (30 g), S. bicolor (30 g), mixture (15 g of Z. mays + 15 g of S. bicolor) were soaked separately in 80% (v/v)...

Author(s): Morakinyo Adetoun Elizabeth, Salawudeen Hammed Opeyemi and Oyedapo Oluokun Oluboade

Pachyrhizus spp. seed extracts control the Sclerotium rolfsii Sacc. mycelial growth

July 2021

The present paper aimed to characterize the bioactivity being exerted on Sclerotium rolfsii Sacc. in vitro by seed aqueous extracts from 64 yam bean (Pachyrhizus spp.) genotypes as well as their maceration times (0, 48 and 72 h). Three experiments were carried out following a completely randomized design with 64 treatments (potato-dextrose-agar PDA+extracts) with two controls (PDA with no extract and PDA+Cabrio® Top...

Author(s): Rodrigo Gonçalves de Lima, César Augusto Ticona-Benavente, Danilo Fernandes da Silva Filho, Leandro Sousa e Silva , Rândrea Grazziella Verçosa Guimarães  and Rogerio Eiji Hanada

Study of seasonality and location effects on the chemical composition of essential oils from Eugenia uniflora leaves

July 2021

The essential oils of Eugenia uniflora leave possess several biological activities but a great variability in their chemical composition is observed. In the present study, gas chromatography and mass spectrometry were applied to examine the essential oil from leaves of four different specimens over the seasons of the year, two of which are located in a habitat of a Brazilian metropolis, and the other two in a natural...

Author(s): Gonçalves Adilson Júnior, Eutimio G. Fernández Núñez, Renata O. Santos, Bryna T. Haraki Otaviano, Rosely L. Imbernon, Fabiana C. Pioker, Marcelo J. Pena Ferreira and Miriam Sannomiya

Metabolic profile of wistar rats after consumption of flour prepared with grains and fruits

July 2021

The occurrence of chronic and degenerative diseases, such as obesity, diabetes, cardiovascular disease (CVD), and cancer is increasing sharply. In the last years, there has been an increase in interest in the consumption of foods with functional properties that are related to weight loss and disease prevention. For these reasons, this study aimed to evaluate the effects of flour prepared with grains and fruits on the...

Author(s): Barbara Bucalem, Barbara Geraldo Amaro, Bruna Gomes Prado, Julia Novacki, Sandra Maria Barbalho, Élen Landgraf Guiguer, Maricelma da Silva Soares de Souza, Manuela dos Santos Bueno, Adriano Cressoni Araújo and Patrícia Cincotto dos Santos Bueno,

Analysis by GC (Ir), GC/MS and mosquito repellent effect of essential oils against Anopheles gambiae: Case of stem bark of Sterculia tragacantha Lindl (Sterculiaceae) from Côte d'Ivoire

July 2021

The objectives of this study were to determine the chemical composition and to evaluate the mosquito repellent property of essential oils extracted from the bark of the stem of Sterculia tragacantha Lindl on Anopheles gambiae, vector of malaria. The essential oil of the stem bark of S. tragacantha Lindl is extracted by hydrodistillation and their chemical compositions were identified by GC (Ir) and GC-MS. This oil has...

Author(s): Sahi Zlankeuhon Jerome, Boua Boua Benson, Ouattara Allassane Foungoye, Mamyrbekova-Bekro Janat Akhanovna and Bekro Yves-Alain

Effects of Boswellia serrata, Zingiber officinale and Ginkgo biloba extracts in combination on memory impairment in mice

July 2021

Cognitive decline induced by oxidative brain damage is the critical pathological hallmark of Alzheimer’s disease. Studies have shown that individual administration of Boswellia serrata Roxb (BS), Zingiber officinale Roscoe (ZO) and Ginkgo biloba L. (GB) extracts improved memory and learning through a different mechanism of actions. This study aims to compare the individual effects of each extract with their...

Author(s): Arsalan Moradian, Masoud Sadeghi Dinani, Ali Hosseini Sharifabad and Mohammad Rabbani

In-vivo anti-inflammatory activity of different parts of Adansonia Digitata

June 2021

The aim of the study is to investigate the anti-inflammatory property of the different parts of Adansonia digitata (Malvaceae) extracts. A. digitata is an important medicinal plant to West Africa including Ghana. The plant is used effectively in folk medicine to treat inflammatory diseases such as joint disorders, asthma, toothache and painful swelling. Carrageenan-induced pedal oedema in 7-day old chicks was was the...

Author(s): Anna Kwarley Quartey, Isaac Ayensu, Emmanuel Orman, Nana Ama Mireku-Gyimah, Yakubu Jibira and Phoebe Esinam Goku  

Phytochemical properties and antimicrobial activity of Buchholzia coriacea and Psychotria microphylla leaf extracts on bacterial pathogens isolated from aquatic environments in Nigeria

June 2021

The use of medicinal plants as alternative therapy for the treatment of microbial infections is significant in the maintenance of good health, especially in developing countries. The aim of this study was to determine the phytochemical composition and antimicrobial activity of Buchholzia coriacea and Psychotria microphylla leaf extracts on bacteria isolated from aquatic environments in Nigeria. Exactly 736 water samples...

Author(s): Ude I. U., Moses I. B., Okoronkwo C., Ovia K., Okafor C., Chukwunwejim C. R., Okata-Nwali O. D., Iroha C. S., Akuma S., Peter I. U., Uzoeto H. O., Ngwu J. N., Onuorah A. L., John-Onwe B. N. and Iroha I. R.  

Anti-bacterial activity of secondary metabolites from Chrysanthemum cinerariaefolium

June 2021

This study evaluated antibacterial activity of Chrysanthemum cinerariaefolium (pyrethrum) flower dichloromethane crude extract, fractions and isolated compounds; pyrethrin II, jasmolin I and cinerolone against methicillin-resistant Staphylococcus aureus (MRSA), Pseudomonas aeruginosa, Staphylococcus aureus and Shigella sonnei. The isolated compounds were obtained by carrying out column chromatography on dichloromethane...

Author(s): Caroline J. Kosgei, Festus Tolo, Josphat C. Matasyoh, Meshack Obonyo, Peter Mwitari, Lucia Keter, Richard Korir and Beatrice Irungu  

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