Pollen extracts from the Soconusco region: Chemical profile and effect against methicillin-resistant Staphylococcus aureus
May 2024
Pollen has been widely known to have beneficial properties for humans, including fighting harmful microorganisms. On the other hand, bacterial resistance is an obvious global problem that has increased over the years. For this reason, the study of the antimicrobial properties of substances such as pollen could play an important role in this area. The present work focused on evaluating the antimocrobial effect of pollen...
In vitro cytotoxic activity of forage peanut (Arachis pintoi Krapov. & W.C. Greg.) oil against leukemic and tumor cell lines
April 2024
Arachis pintoi Krapov. and W.C. Greg. is widely used as forage and displays high seed productivity. Its seed oil contains high levels of phytosterols, mainly β-sitosterol, which has been associated with several biological properties, including cytotoxic activity against different types of cancer. In this study, we investigated the cytotoxic activity of its seed oil against five cancer cell lines using the MTT...
Productivity and picroside contents of Picrorhiza kurroa Royle ex Benth. cultivated at multi-locations in Uttarakhand, India
March 2024
Cultivation is cost effective for conservation and sustainable supply of rare and high value medicinal plants. Assessment of productivity and quality testing validates cultivation and improves trade prospective. Picrorhiza kurroa is a recently domesticated Himalayan medicinal herb. Despite, specific habitat preference above 3000 m in natural habitats, P. kurroa is cultivated successfully below 3000 m under diverse...
Phytochemical screening and biological activities of Copaifera langsdorffii Desf. (Fabaceae) organic extracts
March 2024
This study explores the therapeutic potential of Copaifera langsdorffii Desf. (Fabaceae), commonly known as Copaíba, a legume renowned for its oleoresin extraction. The organic extracts from Copaíba's leaves, stem bark, and wood, using n-hexane, ethyl acetate and methanol were investigated for their antimicrobial, antioxidant and anti-inflammatory activities. In vitro assessments included determining...
Comprehensive evaluation of antiacne properties: HPLC analysis of crude extract from Aloe buettneri leaves against Cutibacterium acnes-induced acne
January 2024
The hydroethanolic extract of Aloe buettneri was assessed for its anti-acne activity in a Cutibacterium acnes-induced acne model in rats as part of this study. Conventional therapies for acne often entail serious side effects. Total phenols, quantified using the Folin-Ciocalteu method, were found to be at a concentration of 16 ± 0.3 mg GAE/g, while total flavonoids, determined using the aluminum chloride method,...
Phytochemical compounds present in COVI-MXG herbal preparation inhibits RNA-Dependent RNA polymerase from SARS-CoV-2: A molecular docking study
December 2023
Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) has been identified as the agent responsible for COVID-19 pandemic. Currently, no therapeutic agents have proven effective in combating the virus. Managing the infection is mainly palliative in nature, involving infection prevention strategies and supportive therapy anchored on drugs that practitioners have had previous usage experience. Previously exploited...
Effects of different nitrogen forms and concentration combinations on American ginseng seedling growth
December 2023
This study investigated the impact of various nitrogen forms on American ginseng (Panax quinquefolius) seedling growth. Thirteen treatments of inorganic and organic nitrogen combinations were tested in the first year and growth indicators were measured. In the second year, treatments with significant growth promotion effects were further verified. The results showed improved growth of American ginseng seedlings when the...
Antimicrobial activities of the extract of shea tree (Vitellaria paradoxa Gaertn. F.) leaf and bark on some selected clinical pathogens
December 2023
The use of plants and plant products in the treatment of various ailments has been with humanity since the dawn of time and the potentials of these plants are so enormous that the continuous search for their hidden treasures is more crucial because of the rise in antibiotic resistance. This study was designed to determine the antimicrobial activities of the shea tree (Vitellaria paradoxa) extracts against some selected...
Qualitative, quantitative composition and evaluation of the antioxidant activity of polar extracts of stem bark of Hexalobus crispiflorus A. Rich (Annonaceae family): Central African species
December 2023
Hexalobus crispiflorus A. Rich., synonym Hexalobus grandiflorus Benth, is a plant in the Central African pharmacopoeia, widely used in the treatment of skin diseases and diabetes. The present study is a contribution to the qualitative and quantitative analysis and evaluation of the antioxidant activity of this plant. Preliminary phytochemical tests carried out on the different crude extracts of H. crispiflorus revealed...
Medicinal plants diversity at King Salman Bin Abdulaziz Royal Natural Reserve in Saudi Arabia and their conservation management
November 2023
King Salman Bin Abdulaziz Royal Natural Reserve (KSRNR) is the largest protected area in the Middle East. This literature review study considered the primary survey on the native medicinal plant diversity at KSRNR in the Kingdom of Saudi Arabia (KSA). KSRNR flora, until now, has about 260 plant species, representing about 12% of the KSA flora. Information was gathered through an extensive literature survey, which...
Ethnobotanical studies in Iran’s rangelands
November 2023
Iran’s rich plant biodiversity includes over 8,400 species, of which more than 2,300 possess medicinal properties. The research community comprised scientific documents on ethnobotany published between 2010 and 2022. Keywords related to ethnobotany, rangeland, and Iran were searched in the databases of scientific journals. All articles were downloaded and read. The collected data were analyzed using Excel. This...
Phytochemicals properties of Carica papaya Linn seeds’ essential oil and their antifungal and antibacterial activities
November 2023
Carica papaya seeds have been used as traditional medicine. This study aims to determine the phytochemicals of papaya seeds essential oils their antimicrobial properties. Polyphenolic content and antioxidant properties were determined with standard methods. GC-MS was used to analyze chemical compounds. Antimicrobial properties were performed using agar diffusion method. MICs, MBCs and MFCs were established based on...
Genipa americana fruit ethanolic extract in the control of environmental infecting agents
November 2023
The choice of substances that are not harmful to man and the environment is a priority in the production of sanitizing products. The aim of this study was to evaluate the disinfectant action and biofilm biomass reduction of the ethanolic extract of Genipa americana fruit. The extract disinfectant efficacy was assessed by modified Kelsey-Sykes, solid surface, and use-dilution methods. Also, the ability of the extract to...
Determination of tetrahydrocannabinol and cannabidiol contents in Cannabis sativa L. samples in Togo using gas chromatography-mass spectrometry
October 2023
Cannabis sativa L. is a widely used recreational drug in Togo, especially among young people. However, little is known about its chemical composition in Sub-Saharan Africa, and specifically in Togo. This study aimed to determine the levels of phytocannabinoids, specifically Δ9-tetrahydrocannabinol (THC) and cannabidiol (CBD), in cannabis samples collected from various towns in Togo using gas chromatography coupled...
Effect of Canarium schweinfurthii leaf and pulp extracts on blood glucose levels in oral glucose load - induced hyperglycemia in Wistar albino rats
September 2023
Canarium schweinfurthii is a common medicinal plant used as food and medicine in communities of central Uganda. Local communities and herbalists commonly used it in the management of diabetes mellitus type 2 with limited information on its effectiveness. Study assessed the hypoglycemic effect of C. schweinfurthii aqueous and total crude leaf and pulp extracts on blood glucose levels in Wistar albino rats. An...
Comprehensive liquid chromatography-mass spectrometry-based metabolomic analysis of Moringa oleifera seeds
September 2023
Moringa oleifera seeds which are less explored and nutriment-rich have attracted scientific interest as the seed kernels contain numerous bioactive components with a variety of traditional uses. Besides its medicinal uses, Moringa oleifera biodiesel has shown remarkable potentiality in conducing to the decrease of greenhouse gases and guaranteeing sustainable supply of energy. In this study, the comprehensive analysis...
Chemical characterization of bottlebrush leaves found in NISLT premises, Samonda, Ibadan, Nigeria.
August 2023
This study investigated the chemical composition of Bottlebrush leaves for its ascribed mythical medicinal uses. Bottlebrush leaves were collected from the Nigerian institute of science laboratory technology premises in Ibadan, Nigeria. Proximate analyses, phytochemical screening, elemental analysis and antioxidant analysis were carried out on the leaves extract. This study has provided a scientific justification that...
Pre-sowing treatments to improve seed germination and seedling growth of Commiphora swynnertonii (Burrt.) and Synadenium glaucescens (Pax.)
July 2023
Medicinal and pesticidal plant propagation is hampered by poor seed germination due to seed dormancy. This study aimed to enhance seed germination and seedling growth using various pre-sowing treatments. A triplicated two-factor experiment in a Randomized Complete Block design was used. Soaking in water at 25°C for 24 h (T1), soaking in 60°C hot water for 10 min (T2), 10 ppm Potassium nitrate (KNO3) treatment...
Anti-inflammatory effect of chaya extracts fractions
June 2023
Patients with Type 2 diabetes often experience chronic inflammation due to the overexpression of NF-kB-regulated pro-inflammatory proteins, such as TNF-alpha, IL-6 and IL-1. Chaya (Cnidoscolus aconitifolius) extracts have been reported to decrease this expression, but fractions of these extracts have not been studied. The present work focused on determining the anti-inflammatory effect of fractions of aqueous extracts...
Inhibition and dissolution of calcium oxalate crystals and kidney stones by the extract of Kalanchoe pinnata
June 2023
Kalanchoe pinnata leaves are used in South Asia as a natural kidney stone treatment. In vitro studies were conducted in supersaturated and artificial urine solutions to evaluate the antiurolithic properties of K. pinnata leaf extract on calcium oxalate monohydrate (COM) and surgically extracted kidney stones. Key organic acids present in the plant extract were also examined in artificial urine to investigate inhibition...
Evaluation of catechin, lupeol, and betulinic acid as markers for the chromatographic quality Control of Albizia coriaria raw materials; an experimental study
May 2023
Albizia coriaria stembark is among the most common raw materials used to manufacture herbal products in Uganda. While the plant material is sourced from the wild, there are neither monographs nor chemical analytical methods for its standardisation. In addition, good cultivation, harvesting, and manufacturing practices are not mandatory. This leads to inconsistent quality of raw materials and products. This work...
Citrullus lanatus plant response to irrigation water magnetized in sandy soil
May 2023
In this study, the productivity of the red watermelon (Citrullus lanatus) crop in arid regions with saline water is examined in relation to the effects of magnetic treatment of irrigation water. The greenhouse experiments compared two treatments (magnetic treatment of irrigation water) and (no magnetic treatment of irrigation water). Magnetic treatment device delta water with a power of 14500 gausses (1.45 T) that was...
Sedative and hypnotic effects of the compatibility of Schisandra chinensis and Polygala tenuifolia on insomnia mice
May 2023
The objective of this study is to study the sedative and hypnotic effects of the compatibility of Schisandra chinensis (SC) and Polygala tenuifolia (PT) on insomnia mice and its mechanisms. The 160 SPF KM mice were divided into 8 groups with 20 each group (10 female and 10 male mice), including control, model, estazolam, SC, PT, SC-PT 1:1, SC-PT 1:2, and SC-PT 2:1 group. Insomnia mice model was established with...
Palyno-morphological assessment of Asteraceae taxa grown in Qarshi Botanical garden at Qarshi Industries (Pvt.) Ltd by using LM and SEM, Pakistan
May 2023
The present study covers the micro-morphological characteristics of 32 taxa of Asteraceae family from Qarshi Botanical Garden at Qarshi Industries (Pvt.) Ltd., Hattar Haripur, Pakistan. The morpho-palynological characters studied were size, shape, polar and equatorial diameter and their exine ornamentation using light microscopy (LM) and scanning electron microscopy (SEM) for its taxonomic significance. In the present...
HPLC determination of polyphenols of the flowers of Digitalis lamarckii, Xeranthemum annuum, Epilobium hirsutum and Silene compacta from Bolu (Turkey)
May 2023
There have been a growing interest since decades in the medicinal plants in terms of preventive health care and treatment of various diseases. On the other hand, polyphenolic compounds present in medicinal plants are known to have antioxidant potency. In the current work, the quantitative HPLC analysis of the flowers of four plants grown in Bolu-Turkey, Silene compacta, Digitalis lamarckii, Xeranthemum annuum L., and...
Phytochemical screening, anti-inflammatory and immunomodulatory activities of Acanthospermum hispidum and Croton zambesicus collected in the Republic of Benin
April 2023
This study aims to characterize chemical groups of metabolites in extracts of Acanthospermum hispidum and Croton zambesicus, and to evaluate their anti-inflammatory activities and their immunomodulatory effect on two pro-inflammatory cytokines (TNFα and IL6). The phytochemical screening was done on the powders of both plants by staining and precipitation reactions. Anti-inflammatory activity was performed in vivo...
Effects of millet on calcium oxalate crystal growth and dissolution
March 2023
The influence of aqueous extract of millet on the crystallization and the dissolution of calcium oxalate (CaOx) crystals were investigated in detail under supersaturated and artificial urinary circumstances in order to understand the effect of the water-soluble components of millet on CaOx kidney stones in humans. To investigate the inhibition effect, different volumes of millet extract were added separately to the...
Amazonian andiroba oil (Carapa guianensis Aubl.) minimizes the formation of postoperative adhesions in the uterus and ovaries of sheep
March 2023
Postoperative adhesions (POA) are postsurgical fibrinolytic connections that can cause complications, and alternative materials have drawn attention to their prevention. The aim of this study is to evaluate the effect of andiroba oil in preventing POA in the uterus and ovaries of sheep. Sixteen female Santa Inês adult sheep were randomly divided into two groups, a control group (CCG) with eight of them submitted...
In vivo hypotensive activity on the albino’s rat and in vitro antioxidant activities of aqueous extract from Guibourtia tessmannii (Harms) J. Leonard (Cesalpiniaceae) stem barks
March 2023
In Central Africa, stem bark from Guibourtia tessmannii is used in traditional pharmacopeia for the treatment of hypertension. The aim of this study was to scientifically verify the traditional use in the treatment of metabolic pathologies such as arterial hypertension and evaluated its pharmacological potential. Phytochemical tests were evaluated by standard method of laboratory. Antioxidant activities were determined...
Phytochemical screening and gas chromatography-mass spectrometry analysis of Euphorbia ingens organic root extract
March 2023
Euphorbia ingens is a woody, succulent tree with ethnomedicinal applications; however, its chemical constituents are not well documented. This study determined the phytochemical profile of Euphorbia ingens dichloromethane-methanol root bark extract. Following sample collection and preparation, extraction was done using the cold percolation technique. This was followed by qualitative phytochemical screening and gas...
Traditional knowledge of plants used against upper respiratory tract affections in the Littoral Region of Cameroon
February 2023
Traditional medicine is used by people as an alternative to orthodox drugs to treat respiratory infections. The aim of this research was to document traditional recipes used in the treatment of upper respiratory tract infections such as pharyngitis, cold, and sinusitis in peri-urban and rural areas of the Littoral Region of Cameroon. Ethnobotanical surveys were carried out using semi-structured interview model in French...
Evaluation of antibiotic efficacy of Ocimum gratissimum L. essential oil against Staphylococcus aureus and Pseudomonas aeruginosa
February 2023
Ocimum gratissimum essential oil (EOGT) has been evaluated for its antibacterial efficacy, and its combinational therapy with antibiotics may enhance the therapeutic efficiency against infection-causing bacteria. Herein, we evaluated the chemical composition of EOGT and its antibiotic efficacy against Staphylococcus aureus and Pseudomonas aeruginosa. GC-MS and GC-FID analyzed EOGT. The antibiotic efficacy was determined...
In-vitro assessment of antibacterial effects of combined crude extracts of S. glaucescens and C. swynnertonii with antibiotics
February 2023
Currently, there is an upsurge of bacterial resistance in single-drug treatment regimens. This has stimulated a growing interest in research and development of new antibacterial agents containing several ingredients as one of the means to combat bacterial resistance. Herb-antibiotic combination therapy is one of the reported effective treatment regimens to combat antimicrobial resistance. This study was aimed to assess...
Medicinal plants for the treatment of malaria and typhoid diseases
January 2023
The review concentrated on current literature on medicinal plants for the treatment of malaria and typhoid related diseases, highlighting information about their ethnobotany. The entire plants reviewed showed strong activities, establishing their different traditional applications and capability to control or eliminate malaria and typhoid diseases. Malaria and typhoid diseases are the most problematic public health...
Pachyrhizus toxicity: Genetic variability of mature and immature seeds and its effects on Sclerotium rolfsii and Ralstonia solanacearum
January 2023
Pachyrhizus seeds-induced toxicity is very well-known to have developed in humans, fishes, insects, and some micro-organisms. Yet, there is a paucity of studies addressing it in their germplasm, as well as its effects on some phytopathogens. This work aimed to assess the Pachyrhizus genetic variability on toxicity and to determine Pachyrhizus extract toxicity on Sclerotium rolfsii and Ralstonia solanacearum in vitro. In...
Bioprospecting of the antifungal activity of Patchouli essential oil (Pogostemon cablin Benth) against strains of the genus Candida
January 2023
The incidence of infections caused by Candida has increased worldwide and these strains are becoming resistant to their respective drugs, requiring the search for new drugs with greater efficacy and safety. Natural products are an alternative means of treatment. The essential oil (EO) stands out among these products, due to some biological activities relevant to human health, including antibiotic and antifungal...
Valuation study on the extracts of Ilex guayusa Loes. as an antioxidant and anti-aging raw material
January 2023
Ilex guayusa Loes. is a medicinal plant used by people of the Ecuadorian Amazon for treating various diseases and for its stimulating properties. In recent years, several studies have shown this plant to possess a high concentration of phenolic compounds and a high antioxidant potential, allowing it to be used as an ingredient for cosmetic formulations. This research confirms the presence of phenolic compounds between...
Determination of total phenolic and flavonoid content, antioxidant and cytotoxic activity of the methanol extract of Acacia nilotica pods
December 2022
Acacia nilotica is a medicinal plant used in Niger republic for the treatment of gastrointestinal diseases. The aim of this study was to investigate total phenolic and flavonoid content, antioxidant and cytotoxic activity of the A. nilotica pods collected from Niger republic. The phytochemical contents were examined by colorimetric methods. Antioxidant activity of the methanol extract was screened using DPPH, ABTS and...
Antiedematogenic activity of Petiveria alliacea L. in bothropic poisoning
December 2022
The biodiversity of the Brazilian biomes inspires interest in research about the biological activities of the molecules present in the flora. In this line, Petiveria alliacea a common plant species in the savanna of Tocantins, reported in the treatment for snakebites, was studied to analyze the phytochemical profile and evaluate the activity on the edema caused by Bothrops moojeni snake venom. A qualitative...
Phytochemical study and anti-radical activity of extracts from the oil seeds of Desbordesia glaucescens (Engl.)Tiegh. from Gabon
November 2022
The report focused on the extraction of oilseeds of Desbordesia glaucescens (Engl.) Tiegh. from Gabon as well as on the phytochemical study and evaluation of the anti-free radical activity of the extracts obtained. The extraction was carried out by cold maceration with solvents of increasing polarities: hexane, tricholroethylene, acetone, ethanol and distilled water. The anti-free radical activity was measured by...
Ethnobotanical study, phytochemical composition and in vitro antioxidant activity of the methanol extracts of thirty-two medicinal plants from Southern Nigeria
October 2022
The prevalent disease conditions globally, the detrimental effects, and the resistance of microorganisms to synthetic drugs are really worrisome. Measures to checkmate these situations include researches on the role of medicinal plants in health care delivery. This study is aimed at assessing the antioxidant activities of some medicinal plants normally used for the treatment of various ailments in southern Nigeria and...
Aqueous extracts of Lentinula edodes, Pleurotus pulmonarius, and Pleurotus sajor-caju: Antifungal activity and inhibition of exoenzyme production by Candida albicans
October 2022
This study was aimed at evaluating the effects of aqueous extracts of Lentinula edodes (SHI), Pleurotus pulmonarius (PUL), and Pleurotus sajor-caju (PSC) on the growth of eight yeast species and the exo-enzyme production by Candida species after exposure to the extracts, which were prepared with the cold extraction methodology and tested against yeasts by the broth microdilution method. Proteinase and phospholipase were...
Ethnobotanical survey and phytochemical screening of aqueous extracts from Detarium microcarpum Guill. & Perr in Mali
October 2022
Detarium microcarpum Guill. & Perr is a tree which belongs to Caesalpiniacea family and can reach up 10 m of height, with a horizontal root system. It is confined to the arid regions of West and Central Africa, where it mainly occurs in savannah. The aim of this work is to collate information on the use of Detarium microcarpum in folk medicine by traditional health practitioners and herbalists. Moreover, a...
Ethnopharmacological investigation on Msindzano, a beauty mask used by Comorian women: What plants for what mixtures, for what applications?
September 2022
Although extensively used by Comorian women, limited information exists on Msindzano beauty masks. Thus an ethnopharmacological survey was conducted on two islands of the Comoros archipelago: Ndzuani and Ngazidja. An open-ended, semi-structured questionnaire was employed for data collection on the different plants used for Msindzano preparation, their different mixtures and their different applications. A total of 348...
Piper rivinoides Kunth: A medicinal plant that preserves bioactive chemical substances in its essential oil throughout the seasons
August 2022
The chemical composition and seasonal variation of essential oils (EO) extracted from the aerial parts of the traditional medicinal plant Piper rivinoides were analyzed using gas chromatography (GC) coupled with mass spectrometry (MS) and GC coupled with flame ionization detector (GC-FID) technique, respectively. The wild plants were collected from two different sites in the Atlantic Forest. The analysis allowed us to...
Ethno botanical study of medicinal plants used by Baka people in the treatment of erectile dysfunction
August 2022
Erectile dysfunction is a disease that is increasingly affecting men. The study examined the traditional use of medicinal plants in the treatment of erectile dysfunction among the Baka people in the eastern region of Cameroon. The study took place over interspersed periods from January 2018 to January 2021 in 9 villages. Forty-four people were interviewed via a questionnaire. One hundred and fifty-nine citations and 71...
Medicinal plants and onychomycosis: potential and evidence of antifungal activity - an integrative review of the literature
July 2022
Onychomycosis is a fungal infection of the nails, also known as nail mycosis and Tinea unguium, which affects 6.9 to 23.2% of the general population. It is most commonly found in people aged 60 years and older. Onychomycosis is caused by dermatophyte fungi, non-dermatophyte filamentous fungi and yeast. Treatment includes topical or oral antifungal drugs. The use of other auxiliary, alternative and/or complementary...
Tracking antibacterial components of Pteris multifida Poir and its antibacterial mechanism
June 2022
Pteris multifida is an effective Chinese herb for treating dysentery caused by Escherichia coli. It might be a good veterinary antibiotic alternative. In this study, we optimized the extraction condition based on the antibacterial activity of crude extracts from P. multifida, tracked its antibacterial components, and investigated their antibacterial activity, as well as its antibacterial mechanism. The results revealed...
Phytochemical composition and in vitro antileishmanial activity of Bidens pilosa, Tithonia diversifolia and Sonchus oleraceus extracts
June 2022
Leishmaniasis is the second-largest parasitic killer in the world (after malaria). Currently, there are no effective vaccines or therapeutic interventions thus creating a gap for new alternative remedies in the management of the disease. Medicinal plants offer this attractive option as antileishmanial agents since they are relatively safe, locally available and affordable. The study assessed antileishmanial activity of...
Medicinal plants of the African traditional pharmacopoeia in the management of bovine trypanosomosis: A review
June 2022
Traditional medicine has remained the most affordable and readily available source of treatment for primary care in poor African communities. Despite the increasingly common practices of traditional medicine to treat animal diseases, this rich endogenous knowledge is not sufficiently documented. The objective of this review is to synthesize information on ethnoveterinary practices to treat bovine trypanosomiasis in...
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