Journal of
Medicinal Plants Research

  • Abbreviation: J. Med. Plants Res.
  • Language: English
  • ISSN: 1996-0875
  • DOI: 10.5897/JMPR
  • Start Year: 2007
  • Published Articles: 3702

JMPR Articles

Angelica gigas Nakai extract ameliorates the effects of cyclophosphamide on immunological and hematopoietic dysfunction in mice

May 2014

The objective of this study was to develop a treatment for immune and hematopoietic system dysfunction in cancer patients. We induced immunosuppression and hematopoietic dysfunction in mice by injection of cyclophosphamide (CPA) and treated the animals with Korean angelica extract (Angelica gigas Nakai), an oriental medicine. Mice were injected with CPA on days 1 and 3 and were orally administered the indicated...

Author(s): Kap Joo Park, Byung Chul Lee, Jae Seok Lee and Myung Hwan Cho

Diversity among 20 accession of three germplasm of the medicinal plant, Ocimum (O. gratissimum, O. sanctum and O. basilicum, Lamiaceae)

May 2014

Ocimum spp, popularly known as Tulsi, has great commercial (food and perfumery industries) and medicinal importance due to antispasmodic, stomachicum, carminative, antimalarial and febrifuge properties. The aroma and flavor in Ocimum spp. is distinct due to the predominant aroma compound eugenol, camphor, citral etc. We used molecular techniques to assess the genetic variability and relatedness of 20 accessions of three...

Author(s): Shanthy Sundaram, Shalini Purwar, Santosh Kumar Singh and Priyanka Dwivedi

Antioxidant capacity of essential oils extracted from Lippia sidoides, Ageratum fastigiatum, Ocotea odorifera, Mikania glauca and their major components

April 2014

Essential oils are biologically important and a large number of studies to evaluate their antioxidant activities have been performed. The aim of this work was to evaluate the antioxidant capacity of the essential oils of Lippia sidoides, Ageratum fastigiatu, Ocotea odorifera, Mikania glauca and their major components, using different assays. The essential oil of L. sidoides exhibited the highest antioxidant capacity,...

Author(s): Luiz Gustavo de Lima Guimarães, Maria das Graças Cardoso, Juliana Andrade, Maria Luisa Teixeira, Marcos de Souza Gomes and Samísia Maria Fernandes Machado

Management of indigenous medicinal plants in Nigeria using phenological information

April 2014

Available information on medicinal plants indicates habitat loss and has heightened the need for more proactive conservation strategies. Conservation efforts in this direction resulted in an eco-pharmacological survey in the West African sub-region by three countries (Nigeria, Ghana and Republic of Benin) to assess frequently used medicinal plants. The result of the socio-economic study based on utilization pattern...

Author(s): Oni, P. I., Jimoh, S. O. and Adebisi, L. A.

In vitro anti-arthritic and thrombolytic activities of methanolic extract of Protium serratum leaves

April 2014

The present study was engineered to find out the anti-arthritic and thrombolytic activity of methanolic extract of Protium serratum by using in vitro method. Methanolic extract of P. serratum was assessed with the inhibition of protein denaturation model which was used to evaluate anti-arthritic potential and this extract assessed with human blood to evaluate thrombolytic effect. The extract showed remarkable...

Author(s): Mohammed Aktar Sayeed, Mohammad Mamun Ur Rashid, Mohammad Fazlul Kabir, Rashedul Alam, Md. Saiful Islam, Rana Dhar and A. T. M Yusuf

A review on pathophysiology of ischemic-reperfusion injury of heart and ameliorating role of flavonoids and polyphenols

April 2014

Ischemia-reperfusion (IR) syndrome is defined as injury caused by the restoration of coronary flow after a period of ischemia. The pathophysiology of ischemia-reperfusion injury involves cellular effect of ischemia, reactive oxygen species and inflammatory cascade. Flavonoids and polyphenols possess unique antioxidant properties and other protective activities which are beneficial for ischemia-reperfusion injury. It is...

Author(s): Jiban Debnath and L. K. Nath

Effect of six environmental variables on five Bupleurum species distribution in Guandi, Wutai, Xiaowutai and Dongling mountains

April 2014

Effects of environmental factors on the spatial distribution of five Bupleurum genera were investigated. Eighty seven samples in total in four mountains were collected; 158, 116, 130 and 128 plant species were recorded in Guandi, Wutai, Xiao Wutai and Dongling mountains, respectively. This study has been focused on five particular species (Bupleurum bicaule Helm, Bupleurum scorzonerifolium Willdenow, Bupleurum sibiricum...

Author(s): L. Nyobe, J. T. Zhang, Q. D. Zhang, S. G. Tian, L. H. Fan and S. T. Huang

Cytotoxic and cytogenetic effects of Convolvulus arvensis extracts on rhabdomyosarcoma (RD) tumor cell line in vitro

April 2014

The present study was designed to investigate the cytotoxicity of (aqueous and methanol) crude extracts of the leaves, stems and roots extracts as well as proteoglycan and glycoside fraction I (FI) of Convolvulus arvensis against human Rhabdomyosarcoma (RD) tumor cell line in vitro. The effect of glycoside FI fraction on mitotic index (MI) of RD cell line was investigated as well. The optical density (OD) of cell growth...

Author(s): Asaad Abdulwahed Bader AL-Asady, Dhamia Kasem Suker and Kawthar Kalaf Hassan

Medicinal plant parts and practices used by communities around the Miombo woodlands of Urumwa, Tanzania

April 2014

A study to document medicinal plants parts and practices in relation to sustainable use was performed in communities around the Miombo woodland of Urumwa in Tanzania. Data collection was based on semi-structured interviews and discussion with key stakeholders. G-tests were used to ascertain differences in medicinal plants practices between women and men. Roots were the commonly used parts for medicine followed by barks....

Author(s): Suzana Augustino, John B. Hall, Fortunatus B. S. Makonda and Romanus C. Ishengoma

Haematological parameters and serum testosterone of West African dwarf rams treated with aqueous extract of Cnidoscolus aconitifolius (Chaya)

April 2014

The effect of Cnidoscolus aconitifolius (Chaya) plant extract on the haematological and serum testosterone of West African dwarf (WAD) breeding rams was carried out. The plant has been used traditionally for both medicinal and non-medicinal purposes. Eight West African dwarf rams were used in this study. The experiment spanned through 14 weeks. The weight of the animals was between 20 to 25 kg and the age between 18 to...

Author(s): M. O. Oyeyemi and Ajani O. S.  

In vitro biological screening and chemical constituents of Euphorbia perbracteata Gage

April 2014

To assess the in vitro biological activity and chemical constituents of Euphorbia perbracteata using different polar solvents, the phytochemical constituents were screened and total phenols, antioxidants, flavonoids content, 2,2-diphenyl-1-picrylhydrazyl (DPPH) free radical scavenging activity and IC50 values were calculated. Antimicrobial assay was carried out by using disc diffusion method and minimum inhibitory...

Author(s): Naidu Sarojini Devi, Yerukala Padma and Rudraraju Reddi Venkata Raju

The first flavonoid isolated from Bromelia laciniosa (Bromeliaceae)

April 2014

Bromelia laciniosa is a native species of the Caatinga biome, popularly known as “macambira” and “macambira de porco”. This paper describes the isolation and structural characterization of the first chemical constituent isolated from the leaves of B. laciniosa, an unprecedented flavonoid in the Bromeliaceae family. The structure was established as 5,7-dihydroxy-3,3',4'-trimethoxyflavone...

Author(s): Raimundo G. de Oliveira-Júnior, Ana P. de Oliveira, Amanda L. Guimarães, Edigênia C. C. Araújo, Raimundo Braz-Filho, Dag O. Øvstedal, Torgils Fossen and Jackson R. G. S. Almeida

Polyphenol derivatives from bioactive butanol phase of the Tunisian narrow-leaved asphodel (Asphodelus tenuifolius Cav., Asphodelaceae)

April 2014

Dichloromethane, ethyl acetate and butanol phases of the organic extract obtained from Asphodelus tenuifolius Cav., a plant growing spontaneously in Tunisia were assessed for antifungal and antibacterial effects using disc diffusion and dilution methods, respectively. The butanol phase exhibited significant antifungal activity against Candida albicans, Candida parapsilosis and Candida krusei and a considerable level of...

Author(s): Khaled Faidi, Saoussen Hammami, Abdelkader Ben Salem, Ridha El Mokni, Mariem Garrab, Maha Mastouri, Mohamed Gorcii, Melika Trabelsi Ayedi, Orazio Taglialatela-Scafati and Zine Mighri

Effect of adenine sulphate on in vitro mass propagation of Stevia rebaudiana Bertoni

April 2014

Stevia rebaudiana, a medicinal plant normally used as a natural herbal sweetener, has documented properties of antimicrobial, antihypertensive and anti-hyperglycemic and hence a boon to diabetic people. An efficient protocol has been developed for the in vitro plant regeneration established from nodal explants of stevia. Best shoot proliferation was observed when nodal explants were inoculated on Murashige and Skoog...

Author(s): Mohd. Kamran Khan, Pragati Misra, Taru Sharma, P. K. Shukla and P. W. Ramteke

Aqueous leaves extract of Artemisia campestris inhibition of the scorpion venom induced hypertension

April 2014

The boiled leaves of Artemisia campestris (Asteraceae) was used as a folk-medicine against ophidian and scorpion envenoming in rural and nomad populations, but its bona fide mechanisms are still unknown. In this report, the effect of the aqueous dry leaves’ extract of this plant on hemodynamic variations induced by Buthus occitanus tunetanus venom was assayed in pregnant and non pregnant rats. Our results showed...

Author(s): Ben Nasr Hamed, Hammami T. Serria, Mahmoudi Lobna and Zeghal Khaled

Acceleration of wound healing activity by Polygonatum odoratum leaf extract in rats

April 2014

Polygonatum odoratum is an important herbal medicine that is used in folk medicine for the treatment of various elements and its components are reported to have various biological effects. This study was conducted to evaluate the effects of topical application of ethanol leaf extract of this plant on the rate of wound healing closure and histology of healed wound. Four groups of male Sprague Dawley rats, all were...

Author(s): Fathi Farag Mughrabi, Harita Hashim, Mahmood A. A., Suzy S. M., Salmah I., Zahra A. A. and KamaL K.

Clinical response of broilers placed on varying levels of aqueous Cassia alata leaf extract

March 2014

This study examined the clinical response of 120 Anak broiler birds to inclusion of Cassia alata aqueous extract at different levels in their water (0, 5, 10 and 15 ml/L). The birds were allotted to four treatments of 10 birds each with three replicates. They were fed ad libitum and data were collected on haematological and serum parameters (packed cell volume, haemoglobin concentration, red blood cell count, white...

Author(s): Amao E. A., Adeoti T. M, Ayandele B and Jimoh A. R.

In vitro antifungal and antioxidant activities of two Benin medicinal plants

March 2014

Casuarina equisetifolia (L.) (Casuarinaceae) and Oxalis corniculata (L.) (Oxalidaceae), two medicinal plants used in Bénin were screened for their antifungal activity against six strains of the genus Aspergillus (Aspergillus fumigatus, Aspergillus flavus, Aspergillus terreus, Aspergillus parasiticus, Aspergillus ochraceus and Aspergillus nidulans). The antioxidant activity and phytochemical constituents were also...

Author(s): Latifou Lagnika, Abdou Madjid O. Amoussa, Semiatou A. Oketokoun, Yann Adjovi and Ambaliou Sanni

Essential oil composition and biomass productivity of Moroccan endemic Thymus satureioides Coss. & Ball. growing in the Agoundis Valley

March 2014

Thymus satureioides Coss. & Ball. (Th. satureioides) is an endemic thyme of Morocco. Thirty two samples of wild T. satureioides were collected from High Atlas Mountains (Valley of Agoundis). The essential oils (EO) isolated by hydrodistillation from the aerial parts were analysed by gas chromatography-mass spectrometry (GC-MS). The yield of EO ranged from 0.2 to 2.3%. Twenty six components, representing more than...

Author(s): Laila Zenasni, Khadija Bakhy, Fatima Gaboun, Rachid Mousadak, Abdelaziz Benjouad, and Chaouki Al Faiz

Phytochemistry and pharmacology of the genus Macaranga: A review

March 2014

The genus Macaranga Thou. (Euphorbiaceae) comprises of about 300 species that are native mainly to the tropics of Africa, Asia, Australia and the Pacific regions. Plants of this genus have a long history of use in traditional medicine to treat cuts, swellings, boils, bruises and sores. Phytochemical work on this genus has reported over 190 secondary metabolites being isolated mainly from the leave extracts of different...

Author(s): Joseph J. Magadula

Antioxidant and antibacterial activity of callus and adventitious root extracts from Rumex vesicarius L.

March 2014

The present work has been carried out for the in vitro production of biologically active constituents from Rumex vesicarius L. cultures. Calli and adventitious roots were tested for their antioxidant and antibacterial activities. Results of preliminary phytochemical screening revealed that cultures were rich in flavonoids, alkaloids, tannins, carbohydrates and/or glycosides, coumarins and cardiac glycosides. Sterols...

Author(s): El-Bakry A. A., Mostafa H. A. M. and Alam Eman A.

Effects of a commercial mixture of herbal essential oils and vitamins (Provital®) and an organic acid (Totacid®) on performance and economical efficiency in broilers: A field study

March 2014

A farm study was carried out to evaluate the inclusion of a commercially available blend of herbal essential oils (Provital) and an organic acid (Totacid) on productive performance and economical efficiency of broiler chickens. A total of 31,800 day old straight run broiler chickens (Ross 308) were allocated to three experimental treatments in three houses (10,600 birds per each) in a commercial farm for 50 days....

Author(s): G. H. Sadeghi, M. Janfadah and S. Moslehi

Biomass and essential oil production from menthe is influenced by compost and lime

March 2014

As a product of secondary metabolism, essential oils may exhibit variation in their composition according to mode of plant cultivation. The application of organic manure has been considered one of the key factors for increasing biomass and essential oil production in most of medicinal plants, as it provides nutrients and increases their uptake. This study aimed to evaluate the influence of organic fertilizer and lime...

Author(s): Patricia Alves Casaes Alves, Eduardo Gross, Larissa Corrêa do Bomfim Costa, Verônica Cordeiro Silva, Fábio Mathias Corrêa and Rosilene Aparecida de Oliveira

Behavioural assessment of Mikania micrantha Kunth roots in Wistar albino rats

March 2014

The present study was designed to evaluate the adaptogenic activity of methanolic and aqueous extract of roots of Mikania micrantha kunth in Wistar albino rats using different experimental models such as anoxia stress tolerance, swimming endurance and immobilisation stress. The plant was subjected to preliminary phytochemical screening. The parameters like anoxia stress tolerance and swimming endurance time were...

Author(s): Sibi P. Ittiyavirah and Sajid K.P.

Antimicrobial potential and bioactive constituents from aerial parts of Vitis setosa Wall.

March 2014

Plants still represent untapped sources of novel compounds with potential therapeutic effects. Hence, the present investigation was carried out to study the in vitro evaluation of antimicrobial potential and to assess the bioactive constituents of the aerial parts of Vitis setosa Wall. The powdered aerial material was extracted with different solvents and examined for antimicrobial activity against Escherichia coli,...

Author(s): Rajagopal Gobalakrishnan, Periyasamy Manikandan, Rameshbabu Bhuvaneswari

In vitro killing rate of Euphorbia heterophylla and Pterocarpus lucens extracts minimum bactericidal concentration (MBC) on some clinical bacterial isolates

March 2014

In vitro antibacterial activity of methanol and ethanol leaf extracts of Euphorbia heterophylla and Pterocarpus lucens were investigated against six bacterial clinical isolates using the tube dilution and agar diffusion methods. Salmonella typhi was the most susceptible to methanol leaf extracts of E. heterophylla with a zone of inhibition ranging from 16 to 24 mm for 12.5 to 100 mg/ml concentration. This was followed...

Author(s): S. A. Adegoke, L. O. Ogundipe and D. A. Agada

Antimicrobial activity and phytochemical screening of various parts of Ixora coccinea

March 2014

Ixora coccinea L. (Rubiaceae) has been used traditionally for a variety of ailments and also cultivated for ornamental purposes. The present study investigated antimicrobial activity of methanolic extracts of various parts of I. coccinea and determined the chemical groups of the active constituents. Antimicrobial activity was assessed using agar disc diffusion, microdilution and thin layer chromatography (TLC)...

Author(s): Mani Maran Marimuthu, Claira Arul Aruldass, Uma Mageswary Sandrasagaran, Suriyati Mohamad, Surash Ramanathan, Sharif Mahsufi Mansor and Vikneswaran Murugaiyah

Anti-depression effect of Chimonanthus salicifolicus essential oil in chronic stressed rats

March 2014

The aim of this study was to investigate the interventional effect of the Chimonanthus salicifolicus essential oil on murine chronic stress-induced anxiety. Rats model of uncertainty empty bottle was established to induce anxiety. The exploratory change, grooming and attack behaviors were observed. After 7 days training period followed by continuous 14 days’ stimulation, rats serum level of glucose (GLU), total...

Author(s): Xueli Zhou ,Yang Yu, Zhou Cheng, Shan Li, Yunguo Zhu and Xiaoling Yang

Assessment of the antimicrobial activity of aqueous and ethanolic extracts of Piper guineense leaves

March 2014

The antimicrobial activity of aqueous and ethanolic extracts of leaves of Piper guineense was determined on some bacteria and fungi, namely, Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, Bacillus subtilis, Candida albicans and Saccharomyces cerevisiae, using agar well diffusion method and minimum inhibitory concentration (MIC). The ethanolic extract was found to show more activity than the aqueous...

Author(s): Anyanwu C. U. and Nwosu G. C.

New cultivation approaches of Artemisia annua L. for a sustainable production of the antimalarial drug artemisinin

March 2014

Artemisia annua L. is an important medicinal plant from which artemisinin was extracted to treat malaria effectively. Artemisinin is isolated from the aerial part of the A. annua harvesting from the wild is causing loss of genetic diversity and habitat destruction. The use of controlled environments can overcome cultivation difficulties and could be a means to manipulate phenotypic variation in bioactive compounds and...

Author(s): Nadali Babaeian Jelodar, Arvind Bhatt, Kamaruzaman Mohamed and Chan Lai Keng

High temperature stress decreases root iridoid glycosides biosynthesis of Scrophularia ningpoensis during florescence

March 2014

Radix Scrophulariaceae is an herbal medicine used as antipyretic and antibacterial. The objective of this study was to investigate the effect of high temperature stress on the secondary metabolites of Scrophularia ningpoensis Hemsl (S. ningpoensis). Potted S. ningpoensis plants of three ecotypes in florescence were subjected to high temperature stress for 15 days. Results showed that under high temperature stress,...

Author(s): Z. S. Liang, Y. Y. An and H. Y. Liu

Medicinal characteristics of Smyrnium cordifolium Boiss. plant extract in rats

March 2014

The most common sleep disorder is insomnia and about 35% of all people suffer from this disturbance. A trend in using herbal medications for this disorder is increasing globally. Current study aimed to investigate the hypnotic characteristics of Smyrnium cordifolium Boiss (SCB) plant extract. From an experimental study, 96 healthy male Wistar rats were equally divided into 12 groups. For hypnotic evaluations, a negative...

Author(s): Naser Abbasi, Elham Mohammadyari, Khairollah Asadollahi, MasoumehTahmasebi, Abangah Ghobad, Morovat Taherikalani

Effect of methyl jasmonate on isoflavonoid accumulation and antioxidant enzymes in Pueraria mirifica cell suspension culture

March 2014

The effect of methyl jasmonate (MJ) on the isoflavonoid accumulation and activities of three antioxidant enzymes (superoxide dismutase, catalase and glutathione peroxidase) were studied in Pueraria mirifica cell suspension culture after MJ elicitation for up to 6 days. Treatment with MJ at a concentration of 1.0 µg/ml induced the highest isoflavonoid contents at the first day after elicitation, when compared to...

Author(s): Tanatorn Saisavoey, Nuttha Thongchul, Polkit Sangvanich and Aphichart Karnchanatat

The influence of extraction solvents on the anticancer activities of Palestinian medicinal plants

March 2014

Palestine has a rich and prestigious heritage of herbal medicines. To investigate the impact of variable extraction techniques on the cytotoxic effects of medicinal plant extracts, 5 well-known medicinal plants from Palestine were extracted with 90% ethanol, 80% methanol, acetone, coconut water, apple vinegar, grape vinegar or 5% acetic acid. The resulting 35 extracts were screened for cytotoxic activities against three...

Author(s): Jawad Alzeer, Balayeshwanth R. Vummidi, Rami Arafeh, Waleed Rimawi, Hatem Saleem and Nathan W. Luedtke

Byrsonima intermedia preparations inhibits trypsin and chymotrypsin activities from Aedes aegypti larval gut

March 2014

This work describes the larvicidal activity of the ethanolic crude extract (EEB) as well as the hexanic (FH), chloroform (FCL), ethyl acetate (FAE) and remaining (FR) fractions obtained from Byrsonima intermedia leaves and bark against Aedes aegypti. Hexanic and remaining fractions from the leaves demonstrated larvicide activity against A. aegypti larvae on the 3rd stage, with LC50 values of 250 and 125 μg/ml-1,...

Author(s): Cristiane Bezerra da Silva, Katlin Suellen Rech, Fernanda Maria Marins Ocampos, Luciane Dalarmi, Vanessa Cristina Godoy Jasinski, Josiane de Fátima Gaspari Dias, Sandra Maria Warumbi Zanin, Vitor Alberto Kerber, Juliana Danna Kulik, Gislene Mari Fujiwara, Maislian de Oliveira, Obdúlio Gomes Miguel and Marilis Dallarmi Miguel

Phytochemical investigation and antioxidant activity of extracts of Lecythis pisonis Camb.

February 2014

Phytochemical investigation of the ethanol extract of leaves, twigs and fruit shell of Lecythis pisonis Camb. revealed the presence of squalene, a- e b-amyrin, lupeol, 3b-friedelinol, ursolic and oleanolic acids, (E)-phytol, sitosterol, stigmasterol, campesterol, quercetin-3-O-rutinoside and kaempferol-3-O-rustinoside. Structural elucidation was achieved using ultra violet (UV), nuclear magnetic resonance (NMR), and...

Author(s): Éverton Leandro de França Ferreira, Thamires Silva Mascarenhas, Jocélia Pereira de Carvalho Oliveira, Mariana Helena Chaves, Bruno Quirino Araújo and Alberto José Cavalheiro

Altered sex expression by plant growth regulators: An overview in medicinal vegetable bitter gourd (Momordica charantia L.)

February 2014

Bitter gourd is one of the popular vegetables for its medicinal values. It is monoecious cucurbitaceous plants which have imbalance sex ratio of male-female flowers that causes lower fruit yield. Different research works on cucurbits like bitter gourd and other related crops in respect of plant growth regulators, plant nutrients, and priming practices have been conducted in different parts of the world. Literatures...

Author(s): MA Baset Mia, MS Islam and ZH Shamsuddin

Assessment of the medicinal uses of plant species found on termitaria in the Pendjari biosphere reserve in Benin

February 2014

Medicinal plants are important in the life of African populations and there is nowadays an increasing need to gathering information related to them. In order to highlight the importance of termitaria to local populations, we investigated within the Pendjari Biosphere reserve the medicinal uses made from plant species found in association with them. We laid out plots in fields and fallows surrounding the Pendjari...

Author(s): H. O. Dossou-Yovo, F. G. Vodouhe and B. Sinsin

Hypotensive activity, toxicology and histopathology of different extracts of Berberis vulgaris

February 2014

A number of plants have been used widely in the traditional system of medicine or Tibb-e-Unani (Unani medicine) in the management of many diseases but these mostly, have not been investigated for their described effects. In this study, the hypotensive, toxicology and histological activities were studied in normotensive albino rats at different doses of ethanolic extract of root pulp (BRE) and aqueous extract of root...

Author(s): Aisha Azmat and Muhammad Ahmed

Antimicrobial activity of the leaf extract and fractions of Lupinus arboreus

February 2014

The antimicrobial effect of the leaf extract and fractions of Lupinus arboreus was investigated. The crude methanol extract (CME) of the dried leaves obtained by 48 h cold maceration was fractionated into n-hexane fraction (HEF), ethyl acetate fraction (EAF), and methanol fraction (MEF); and evaluated using modified agar-well diffusion method. The results showed that the extract and fractions at varying concentrations,...

Author(s): Ohadoma S. C., Nnatuanya I., Amazu L. U. and Okolo C. E.

Antioxidant and anticancer activities of Moringa oleifera leaves

February 2014

Moringa oleifera leaves extracted with methanol and dichloromethane were screened for antioxidant activity. The in vitro cancer antiproliferative and chemopreventive properties were also investigated. Radical scavenging assays with 1, 1-diphenyl-2-picrylhydrazyl (DPPH) and 2,2´-azino-bis 3-ethylbenzothiazoline-6-sulfonic acid (ABTS) were used to determine the antioxidant activity. The antiproliferative assay was...

Author(s): Suphachai Charoensin

An anatomical study of medicinal species Ajuga orientalis L. (Lamiaceae) from Turkey

February 2014

Ajuga orientalis (Lamiaceae), with a wide distribution area in Turkey, is a traditionally used medicine in the treatment of some skin diseases in Anatolia. The aim of this study was to determine the anatomical characteristics of the root, stem, leaf, petiole, calyx and corolla of  medicinal species of A. orientalis in cross sections. As a result of the study, it was found out that the pith rays of the root composed...

Author(s): İlkay ÖZTÜRK ÇALI

Antibacterial and cytotoxic antibacterial potential of ethanol extract and fractions from Aristolochia galeata Mart. ex Zucc

February 2014

The aim of this investigation was to evaluate the phytochemical, antibacterial and cytotoxic activities of ethanol extract and hexane, dichlorometane, ethyl acetate and hydroethanolic fractions from Aristolochia galeata’s rhizomes. The minimum inhibitory concentration (MIC) and minimum lethal concentration (MLC) were evaluated by the broth microdilution assay to investigate the antibacterial activity of various...

Author(s): Álan Alex Aleixo, Vidyleison Neves Camargos, Ana Cláudia dos Santos Pereira Andrade, Karina Marjorie Silva Herrera, Rosy Iara Maciel de Azambuja Ribeiro, Kamilla Monteiro dos Santos, Juliana Teixeira de Magalhães, José Carlos Magalhães, Luciana Alves Rodrigues dos Santos Lima and Jaqueline Maria Siqueira Ferreira

Phytochemical and in vitro anti-bacterial properties of Hibiscus sabdariffa L (Roselle) juice

February 2014

The anti-bacterial properties of aqueous and ethanol extracts of the calyces of Hibiscus sabdariffa on five bacteria genera, namely, Escherichia coli, Staphylococcus aureus, Salmonella typhi, Shigella  dysenteriae and Streptococcus mutans were evaluated using agar well and disc diffusion methods. Six bioactive compounds were identified from phytochemical analysis of the juice extract of H. sabdariffa. Analysis...

Author(s): Alaga T. O., Edema M. O., Atayese A. O., Bankole M.O.

Evaluation of whitening efficacy and safety of the water extract from bamboo shavings

February 2014

This aim of this study was to evaluate the whitening efficacy of the water extract from bamboo shavings (WEBS) in malignant melanoma cells (B-16) of mice. The safety of WEBS was evaluated by the acute oral toxicity test, the repeated skin irritation test and the acute eye irritation test was also evaluated. WEBS showed strong inhibitory effects against the activity of tyrosinase in B-16 cells in a dose dependent manner,...

Author(s): Zhang Jianyou, Gong Jinyan, Lu Baiyi, Wu Xiaoqin and Zhang Ying

Influence of oil content and yield of Foeniculum vulgare Mill. cv. Soroksary seeds by adapting different plant densities

February 2014

In this experiment, the effect of different plant densities on the oil content and yield of Foeniculum vulgare Mill. Cv. Soroksary seeds was studied at the Faculty of Agricultural Sciences and Engineering, Karaj, Iran (Latitude 35° 47´ N and Longitude 50° 59´ E) in 2008. Different spacing studied were 10, 15, 20, 25, and 30 cm and the distance between rows in all treatments was 40 cm using a complete...

Author(s): Jalal Khorshidi, Seyed Fazel Mirahmadi, Mohammad Fakhr Tabatabaei, Reza Omidbaigi and Fatemeh Sefidkon

Phytochemical analysis and biological activity of a precipitate from Pavetta crassipes

February 2014

Precipitate obtained from the aqueous extract of a Pavetta crassipes K. Schum (Rubiaceae) was analyzed for biological activity and phytochemical makeup. Phytochemical studies of the precipitate showed the presence of flavonoids. Antimicrobial studies showed that the precipitate inhibited the growths of Corynebacterium ulcerans, Escherichia coli and Pseudomonas aeruginosa at 6.25 mg/ml with corresponding minimum...

Author(s): Bello Isaac Asusheyi, Ndukwe George Iloegbulam and Audu Oladimeji Tokumbo

Recovery effect of Zingiber officinale on testis tissue after treatment with gentamicin in rats

February 2014

Ginger rhizome (Zingiber officinale R., family: Zingiberaceae) is used medicinally and as a culinary spice. Gentamicin is synthetic antibacterial agent antibiotic with a very broad spectrum against microbial pathogens, especially the gram-negative. The aim of this study was to investigate the recovery effect of ginger on testis after treatment with gentamicin in rats. The forty male Wistar rats were selected and...

Author(s): A. Zahedi and A. Khaki⊃

Effects of Huanglian Jiedu Decoction (HLJDD) on fever induced by lipopolysaccharide and inflammation induced by carrageenan

February 2014

This study aimed to investigate the antifebrile and anti-inflammatory effect of Huanglian Jiedu Decoction (HLJDD). The rabbits received intravenous injection of lipopolysaccharide (LPS) after orally administered with HLJDD and the rectal temperatures of rabbits were monitored. The concentrations of interleukin-1 beta (IL-1β) and tumor necrosis factor alpha (TNF-α) in serum were assayed using rabbit IL-1β...

Author(s): Ran Li, Lilong Jia, Xiu Dong, Juncai Liu and Haibo Li

Comparative genetic and chemical profiling performed on Alstonia scholaris in China and its implications to standardization of Traditional Chinese Medicine

February 2014

Validity of traditional Chinese medicine (TCM) is oppugned very often because of the bugs of quality, effectiveness, and repeatability. Standardization of TCMs is one way to make a change. How to realize standardization of TCMs and with what measures to shape the quality control system, is provoking much debate in the TCM field. Genetic and chemical profiling were comparatively performed on Alstonia scholaris in China...

Author(s): Zhaoyang Zhang, Xiaodong Luo, and Sheng Li

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